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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PRDM14

Z-value: 0.42

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Transcription factors associated with PRDM14

Gene Symbol Gene ID Gene Info
ENSG00000147596.3 PR/SET domain 14

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PRDM14hg19_v2_chr8_-_70983506_709835620.266.2e-01Click!

Activity profile of PRDM14 motif

Sorted Z-values of PRDM14 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_46692457 0.38 ENST00000468443.1
homeobox B8
chr4_+_141677577 0.32 ENST00000609937.1
RP11-102N12.3
chr5_-_108063949 0.23 ENST00000606054.1
long intergenic non-protein coding RNA 1023
chr11_+_62475130 0.23 ENST00000294117.5
guanine nucleotide binding protein (G protein), gamma 3
chr8_+_101349823 0.23 ENST00000519566.1
KB-1991G8.1
chr17_-_46691990 0.18 ENST00000576562.1
homeobox B8
chr12_-_56326402 0.16 ENST00000547925.1
within bgcn homolog (Drosophila)
chr17_-_46692287 0.16 ENST00000239144.4
homeobox B8
chr1_-_155006224 0.14 ENST00000368424.3
DC-STAMP domain containing 2
chr1_-_155006254 0.13 ENST00000295536.5
DC-STAMP domain containing 2
chr13_-_34250861 0.11 ENST00000445227.1
ENST00000454681.2
RP11-141M1.3
chr15_+_69850521 0.10 ENST00000558781.1
RP11-279F6.1
chr3_-_134092561 0.09 ENST00000510560.1
ENST00000504234.1
ENST00000515172.1
angiomotin like 2
chr17_+_39994032 0.09 ENST00000293303.4
ENST00000438813.1
kelch-like family member 10
chr6_+_133561725 0.09 ENST00000452339.2
eyes absent homolog 4 (Drosophila)
chr4_-_10459009 0.08 ENST00000507515.1
zinc finger protein 518B
chr19_+_38880252 0.08 ENST00000586301.1
sprouty-related, EVH1 domain containing 3
chr15_-_45694380 0.08 ENST00000561148.1
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr11_-_46615498 0.08 ENST00000533727.1
ENST00000534300.1
ENST00000528950.1
ENST00000526606.1
autophagy/beclin-1 regulator 1
chr9_+_132099158 0.08 ENST00000444125.1
RP11-65J3.1
chr1_-_42384343 0.07 ENST00000372584.1
human immunodeficiency virus type I enhancer binding protein 3
chr17_-_17485731 0.07 ENST00000395783.1
phosphatidylethanolamine N-methyltransferase
chr5_+_32710736 0.07 ENST00000415685.2
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr2_-_145277882 0.07 ENST00000465070.1
ENST00000444559.1
zinc finger E-box binding homeobox 2
chr17_+_75450099 0.07 ENST00000586433.1
septin 9
chr11_-_62439727 0.06 ENST00000528862.1
chromosome 11 open reading frame 48
chr19_+_3572758 0.06 ENST00000416526.1
high mobility group 20B
chr12_-_49351228 0.05 ENST00000541959.1
ENST00000447318.2
ADP-ribosylation factor 3
chr5_-_135528822 0.05 ENST00000607574.1
AC009014.3
chr17_+_75450075 0.05 ENST00000592951.1
septin 9
chr1_+_156052354 0.05 ENST00000368301.2
lamin A/C
chr1_+_39796810 0.05 ENST00000289893.4
microtubule-actin crosslinking factor 1
chr10_+_12171636 0.05 ENST00000379051.1
ENST00000379033.3
ENST00000441368.1
ENST00000298428.9
ENST00000304267.8
Sec61 alpha 2 subunit (S. cerevisiae)
chr12_-_49351148 0.04 ENST00000398092.4
ENST00000539611.1
ADP-ribosylation factor 3
ADP-ribosylation factor 3
chr11_-_65625014 0.04 ENST00000534784.1
cofilin 1 (non-muscle)
chr19_+_49838653 0.04 ENST00000598095.1
ENST00000426897.2
ENST00000323906.4
ENST00000535669.2
ENST00000597602.1
ENST00000595660.1
CD37 molecule
chr1_+_27114589 0.04 ENST00000431541.1
ENST00000449950.2
ENST00000374145.1
phosphatidylinositol glycan anchor biosynthesis, class V
chr14_-_21492251 0.04 ENST00000554398.1
NDRG family member 2
chr16_-_55866997 0.04 ENST00000360526.3
ENST00000361503.4
carboxylesterase 1
chr11_-_65624415 0.03 ENST00000524553.1
ENST00000527344.1
cofilin 1 (non-muscle)
chr1_+_109102652 0.03 ENST00000370035.3
ENST00000405454.1
family with sequence similarity 102, member B
chr17_+_41924536 0.03 ENST00000317310.4
CD300 molecule-like family member g
chr1_+_36621174 0.03 ENST00000429533.2
MAP7 domain containing 1
chr12_-_49351303 0.03 ENST00000256682.4
ADP-ribosylation factor 3
chr17_+_36873677 0.03 ENST00000471200.1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr19_+_39109735 0.03 ENST00000593149.1
ENST00000248342.4
ENST00000538434.1
ENST00000588934.1
ENST00000545173.2
ENST00000589307.1
ENST00000586513.1
ENST00000591409.1
ENST00000592558.1
eukaryotic translation initiation factor 3, subunit K
chr6_-_109777128 0.03 ENST00000358807.3
ENST00000358577.3
microtubule associated monooxygenase, calponin and LIM domain containing 1
chr17_+_75450146 0.02 ENST00000585929.1
ENST00000590917.1
septin 9
chr17_-_17726907 0.02 ENST00000423161.3
sterol regulatory element binding transcription factor 1
chrX_+_15525426 0.02 ENST00000342014.6
BMX non-receptor tyrosine kinase
chr19_-_49314269 0.02 ENST00000545387.2
ENST00000316273.6
ENST00000402551.1
ENST00000598162.1
ENST00000599246.1
branched chain amino-acid transaminase 2, mitochondrial
chrX_+_51636629 0.02 ENST00000375722.1
ENST00000326587.7
ENST00000375695.2
melanoma antigen family D, 1
chr17_-_19651654 0.02 ENST00000395555.3
aldehyde dehydrogenase 3 family, member A1
chr19_-_49314169 0.02 ENST00000597011.1
ENST00000601681.1
branched chain amino-acid transaminase 2, mitochondrial
chr3_+_155838337 0.02 ENST00000490337.1
ENST00000389636.5
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr12_+_3600356 0.02 ENST00000382622.3
protein arginine methyltransferase 8
chr5_-_16936340 0.02 ENST00000507288.1
ENST00000513610.1
myosin X
chr17_-_2117600 0.02 ENST00000572369.1
SMG6 nonsense mediated mRNA decay factor
chr20_-_3154162 0.02 ENST00000360342.3
Homo sapiens leucine zipper, putative tumor suppressor family member 3 (LZTS3), mRNA.
chr9_+_132597722 0.02 ENST00000372429.3
ENST00000315480.4
ENST00000358355.1
ubiquitin specific peptidase 20
chr12_+_121647868 0.02 ENST00000359949.7
ENST00000541532.1
ENST00000543171.1
ENST00000538701.1
purinergic receptor P2X, ligand-gated ion channel, 4
chr17_-_19651668 0.02 ENST00000494157.2
ENST00000225740.6
aldehyde dehydrogenase 3 family, member A1
chr7_-_124405681 0.02 ENST00000303921.2
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr2_-_208030295 0.01 ENST00000458272.1
Kruppel-like factor 7 (ubiquitous)
chr4_+_4861385 0.01 ENST00000382723.4
msh homeobox 1
chr14_+_89290965 0.01 ENST00000345383.5
ENST00000536576.1
ENST00000346301.4
ENST00000338104.6
ENST00000354441.6
ENST00000380656.2
ENST00000556651.1
ENST00000554686.1
tetratricopeptide repeat domain 8
chr12_-_124456598 0.01 ENST00000539761.1
ENST00000539551.1
coiled-coil domain containing 92
chr19_-_5624057 0.01 ENST00000590262.1
scaffold attachment factor B2
chr6_+_43140095 0.01 ENST00000457278.2
serum response factor (c-fos serum response element-binding transcription factor)
chr12_+_121647962 0.01 ENST00000542067.1
purinergic receptor P2X, ligand-gated ion channel, 4
chr1_+_65730385 0.01 ENST00000263441.7
ENST00000395325.3
DnaJ (Hsp40) homolog, subfamily C, member 6
chr3_+_10289707 0.01 ENST00000287652.4
TatD DNase domain containing 2
chr1_+_27668505 0.01 ENST00000318074.5
synaptotagmin-like 1
chr3_-_47517302 0.01 ENST00000441517.2
ENST00000545718.1
SREBF chaperone
chr17_-_73775839 0.01 ENST00000592643.1
ENST00000591890.1
ENST00000587171.1
ENST00000254810.4
ENST00000589599.1
H3 histone, family 3B (H3.3B)
chr1_+_36621529 0.01 ENST00000316156.4
MAP7 domain containing 1
chr12_-_52967600 0.00 ENST00000549343.1
ENST00000305620.2
keratin 74
chr1_-_27216729 0.00 ENST00000431781.2
ENST00000374135.4
GPN-loop GTPase 2
chr1_+_153963227 0.00 ENST00000368567.4
ENST00000392558.4
ribosomal protein S27
chr19_-_6279932 0.00 ENST00000252674.7
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr3_+_37035263 0.00 ENST00000458205.2
ENST00000539477.1
mutL homolog 1
chr3_-_114477962 0.00 ENST00000471418.1
zinc finger and BTB domain containing 20

Network of associatons between targets according to the STRING database.

First level regulatory network of PRDM14

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.1 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.1 GO:0006601 creatine biosynthetic process(GO:0006601)
0.0 0.0 GO:0006550 isoleucine catabolic process(GO:0006550)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.1 GO:2000769 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0015068 amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.0 0.1 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.2 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)