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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for RXRG

Z-value: 2.17

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Transcription factors associated with RXRG

Gene Symbol Gene ID Gene Info
RXRG
ENSG00000143171.8 retinoid X receptor gamma

Activity profile of RXRG motif

Sorted Z-values of RXRG motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_74212073 2.35 ENST00000441217.1
AC073046.25
AC073046.25
chr2_+_105471969 1.41 ENST00000361360.2
POU3F3
POU class 3 homeobox 3
chr15_+_41221536 1.40 ENST00000249749.5
DLL4
delta-like 4 (Drosophila)
chr6_-_34664612 1.19 ENST00000374023.3
ENST00000374026.3
C6orf106
chromosome 6 open reading frame 106
chr1_+_202317855 1.17 ENST00000356764.2
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr1_-_183538319 1.10 ENST00000420553.1
ENST00000419402.1
NCF2
neutrophil cytosolic factor 2
chr19_-_1174226 1.06 ENST00000587024.1
ENST00000361757.3
SBNO2
strawberry notch homolog 2 (Drosophila)
chr4_-_90758227 1.03 ENST00000506691.1
ENST00000394986.1
ENST00000506244.1
ENST00000394989.2
ENST00000394991.3
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr17_+_7211280 1.02 ENST00000419711.2
ENST00000571955.1
ENST00000573714.1
EIF5A
eukaryotic translation initiation factor 5A
chrX_-_16888276 1.01 ENST00000493145.1
RBBP7
retinoblastoma binding protein 7
chr7_-_35734176 1.00 ENST00000413517.1
ENST00000438224.1
HERPUD2
HERPUD family member 2
chr2_+_242913327 0.96 ENST00000426962.1
AC093642.3
AC093642.3
chr17_+_3627185 0.96 ENST00000325418.4
GSG2
germ cell associated 2 (haspin)
chr16_+_71660052 0.94 ENST00000567566.1
MARVELD3
MARVEL domain containing 3
chr6_+_35227449 0.93 ENST00000373953.3
ENST00000440666.2
ENST00000339411.5
ZNF76
zinc finger protein 76
chr11_-_47447970 0.90 ENST00000298852.3
ENST00000530912.1
PSMC3
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr19_+_6361841 0.90 ENST00000596605.1
CLPP
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr17_-_72889697 0.90 ENST00000310226.6
FADS6
fatty acid desaturase 6
chr17_+_47074758 0.90 ENST00000290341.3
IGF2BP1
insulin-like growth factor 2 mRNA binding protein 1
chr9_-_131534188 0.87 ENST00000414921.1
ZER1
zyg-11 related, cell cycle regulator
chr12_+_57998400 0.87 ENST00000548804.1
ENST00000550596.1
ENST00000551835.1
ENST00000549583.1
DTX3
deltex homolog 3 (Drosophila)
chr19_+_52873166 0.87 ENST00000424032.2
ENST00000600321.1
ENST00000344085.5
ENST00000597976.1
ENST00000422689.2
ZNF880
zinc finger protein 880
chr17_+_59477233 0.87 ENST00000240328.3
TBX2
T-box 2
chr12_-_120806960 0.86 ENST00000257552.2
MSI1
musashi RNA-binding protein 1
chr17_-_43568062 0.83 ENST00000421073.2
ENST00000584420.1
ENST00000589780.1
ENST00000430334.3
PLEKHM1
pleckstrin homology domain containing, family M (with RUN domain) member 1
chr6_-_32122106 0.83 ENST00000428778.1
PRRT1
proline-rich transmembrane protein 1
chr11_+_65122216 0.82 ENST00000309880.5
TIGD3
tigger transposable element derived 3
chr3_+_14989076 0.82 ENST00000413118.1
ENST00000425241.1
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr16_+_70207686 0.81 ENST00000541793.2
ENST00000314151.8
ENST00000565806.1
ENST00000569347.2
ENST00000536907.2
CLEC18C
C-type lectin domain family 18, member C
chr17_+_47075023 0.81 ENST00000431824.2
IGF2BP1
insulin-like growth factor 2 mRNA binding protein 1
chr11_-_47447767 0.80 ENST00000530651.1
ENST00000524447.2
ENST00000531051.2
ENST00000526993.1
ENST00000602866.1
PSMC3
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr1_+_202317815 0.79 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr14_+_38065052 0.79 ENST00000556845.1
TTC6
tetratricopeptide repeat domain 6
chr11_-_65430251 0.79 ENST00000534283.1
ENST00000527749.1
ENST00000533187.1
ENST00000525693.1
ENST00000534558.1
ENST00000532879.1
ENST00000532999.1
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr19_+_50354430 0.78 ENST00000599732.1
PTOV1
prostate tumor overexpressed 1
chr17_-_73844722 0.78 ENST00000586257.1
WBP2
WW domain binding protein 2
chr22_-_29784519 0.78 ENST00000357586.2
ENST00000356015.2
ENST00000432560.2
ENST00000317368.7
AP1B1
adaptor-related protein complex 1, beta 1 subunit
chr12_-_98897617 0.78 ENST00000501499.1
RP11-181C3.1
Uncharacterized protein
chr10_-_81203972 0.78 ENST00000372333.3
ZCCHC24
zinc finger, CCHC domain containing 24
chr17_+_36584662 0.77 ENST00000431231.2
ENST00000437668.3
ARHGAP23
Rho GTPase activating protein 23
chr11_-_65429891 0.77 ENST00000527874.1
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr1_+_109642799 0.76 ENST00000602755.1
SCARNA2
small Cajal body-specific RNA 2
chr19_-_14117074 0.76 ENST00000588885.1
ENST00000254325.4
RFX1
regulatory factor X, 1 (influences HLA class II expression)
chr17_+_7210898 0.75 ENST00000572815.1
EIF5A
eukaryotic translation initiation factor 5A
chr22_-_30234218 0.75 ENST00000307790.3
ENST00000542393.1
ENST00000397771.2
ASCC2
activating signal cointegrator 1 complex subunit 2
chr6_+_24495185 0.74 ENST00000348925.2
ALDH5A1
aldehyde dehydrogenase 5 family, member A1
chr22_-_43567750 0.73 ENST00000494035.1
TTLL12
tubulin tyrosine ligase-like family, member 12
chr19_-_6424283 0.72 ENST00000595258.1
ENST00000595548.1
KHSRP
KH-type splicing regulatory protein
chr17_-_31404 0.72 ENST00000343572.7
DOC2B
double C2-like domains, beta
chr14_+_59100774 0.72 ENST00000556859.1
ENST00000421793.1
DACT1
dishevelled-binding antagonist of beta-catenin 1
chrX_-_30327495 0.72 ENST00000453287.1
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr2_-_121624973 0.71 ENST00000603720.1
RP11-297J22.1
RP11-297J22.1
chr1_+_1243947 0.71 ENST00000379031.5
PUSL1
pseudouridylate synthase-like 1
chr19_-_14228541 0.71 ENST00000590853.1
ENST00000308677.4
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr10_-_17496222 0.71 ENST00000377602.4
ST8SIA6
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr19_+_50354462 0.70 ENST00000601675.1
PTOV1
prostate tumor overexpressed 1
chr7_-_767249 0.70 ENST00000403562.1
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr22_-_29663954 0.69 ENST00000216085.7
RHBDD3
rhomboid domain containing 3
chr15_+_76352178 0.69 ENST00000388942.3
C15orf27
chromosome 15 open reading frame 27
chr16_+_67700673 0.69 ENST00000403458.4
ENST00000602365.1
C16orf86
chromosome 16 open reading frame 86
chr6_+_43737939 0.68 ENST00000372067.3
VEGFA
vascular endothelial growth factor A
chr3_+_52454971 0.68 ENST00000465863.1
PHF7
PHD finger protein 7
chr19_+_9251052 0.68 ENST00000247956.6
ENST00000360385.3
ZNF317
zinc finger protein 317
chr11_-_1587166 0.68 ENST00000331588.4
DUSP8
dual specificity phosphatase 8
chr12_+_117176113 0.67 ENST00000319176.7
RNFT2
ring finger protein, transmembrane 2
chr11_-_62439727 0.67 ENST00000528862.1
C11orf48
chromosome 11 open reading frame 48
chr19_-_6279932 0.67 ENST00000252674.7
MLLT1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr17_+_7211656 0.66 ENST00000416016.2
EIF5A
eukaryotic translation initiation factor 5A
chr19_+_7587555 0.66 ENST00000601003.1
MCOLN1
mucolipin 1
chr5_+_170846640 0.65 ENST00000274625.5
FGF18
fibroblast growth factor 18
chr19_-_10047219 0.64 ENST00000264833.4
OLFM2
olfactomedin 2
chrX_-_70474377 0.64 ENST00000373978.1
ENST00000373981.1
ZMYM3
zinc finger, MYM-type 3
chr20_+_42295745 0.63 ENST00000396863.4
ENST00000217026.4
MYBL2
v-myb avian myeloblastosis viral oncogene homolog-like 2
chrX_-_49042778 0.63 ENST00000538114.1
ENST00000376310.3
ENST00000376317.3
ENST00000417014.1
PRICKLE3
prickle homolog 3 (Drosophila)
chr3_-_50329990 0.62 ENST00000417626.2
IFRD2
interferon-related developmental regulator 2
chr19_+_50354393 0.61 ENST00000391842.1
PTOV1
prostate tumor overexpressed 1
chr11_+_65383227 0.61 ENST00000355703.3
PCNXL3
pecanex-like 3 (Drosophila)
chr2_+_27301435 0.60 ENST00000380320.4
EMILIN1
elastin microfibril interfacer 1
chr3_-_50329835 0.60 ENST00000429673.2
IFRD2
interferon-related developmental regulator 2
chr19_+_18303992 0.60 ENST00000599612.2
MPV17L2
MPV17 mitochondrial membrane protein-like 2
chr6_+_43738444 0.59 ENST00000324450.6
ENST00000417285.2
ENST00000413642.3
ENST00000372055.4
ENST00000482630.2
ENST00000425836.2
ENST00000372064.4
ENST00000372077.4
ENST00000519767.1
VEGFA
vascular endothelial growth factor A
chr1_-_153919128 0.59 ENST00000361217.4
DENND4B
DENN/MADD domain containing 4B
chrX_+_48687283 0.59 ENST00000338270.1
ERAS
ES cell expressed Ras
chr17_+_33307503 0.59 ENST00000378526.4
ENST00000585941.1
ENST00000262327.5
ENST00000592690.1
ENST00000585740.1
LIG3
ligase III, DNA, ATP-dependent
chr19_+_12780512 0.58 ENST00000242796.4
WDR83
WD repeat domain 83
chr11_+_327171 0.58 ENST00000534483.1
ENST00000524824.1
ENST00000531076.1
RP11-326C3.12
RP11-326C3.12
chr11_+_46722368 0.58 ENST00000311764.2
ZNF408
zinc finger protein 408
chr12_-_56223363 0.58 ENST00000546957.1
DNAJC14
DnaJ (Hsp40) homolog, subfamily C, member 14
chr19_-_50432711 0.58 ENST00000597723.1
ENST00000599788.1
ENST00000596217.1
ENST00000593652.1
ENST00000599567.1
ENST00000600935.1
ENST00000596011.1
ENST00000596022.1
ENST00000597295.1
NUP62
IL4I1
nucleoporin 62kDa
interleukin 4 induced 1
chrX_-_47509994 0.58 ENST00000343894.4
ELK1
ELK1, member of ETS oncogene family
chrX_+_153672468 0.58 ENST00000393600.3
FAM50A
family with sequence similarity 50, member A
chr9_-_110251836 0.58 ENST00000374672.4
KLF4
Kruppel-like factor 4 (gut)
chr17_-_7832753 0.56 ENST00000303790.2
KCNAB3
potassium voltage-gated channel, shaker-related subfamily, beta member 3
chr16_+_20912114 0.56 ENST00000567954.1
LYRM1
LYR motif containing 1
chr16_-_23724518 0.56 ENST00000457008.2
ERN2
endoplasmic reticulum to nucleus signaling 2
chr19_-_4124079 0.56 ENST00000394867.4
ENST00000262948.5
MAP2K2
mitogen-activated protein kinase kinase 2
chr3_-_125655882 0.55 ENST00000340333.3
ALG1L
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase-like
chr9_-_140009130 0.55 ENST00000497375.1
ENST00000371579.2
DPP7
dipeptidyl-peptidase 7
chr11_-_65430554 0.55 ENST00000308639.9
ENST00000406246.3
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr4_+_184826418 0.55 ENST00000308497.4
ENST00000438269.1
STOX2
storkhead box 2
chr2_-_228028829 0.55 ENST00000396625.3
ENST00000329662.7
COL4A4
collagen, type IV, alpha 4
chr10_+_88718397 0.55 ENST00000372017.3
SNCG
synuclein, gamma (breast cancer-specific protein 1)
chr19_-_50432654 0.54 ENST00000596680.1
ENST00000594673.1
ENST00000597029.1
NUP62
nucleoporin 62kDa
chr1_-_154946792 0.54 ENST00000412170.1
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr22_-_29663690 0.54 ENST00000406335.1
RHBDD3
rhomboid domain containing 3
chr22_+_30821732 0.54 ENST00000355143.4
MTFP1
mitochondrial fission process 1
chr17_-_79829190 0.54 ENST00000581876.1
ENST00000584461.1
ENST00000583868.1
ENST00000400721.4
ENST00000269321.7
ARHGDIA
Rho GDP dissociation inhibitor (GDI) alpha
chr7_+_143078652 0.54 ENST00000354434.4
ENST00000449423.2
ZYX
zyxin
chr22_+_19705928 0.54 ENST00000383045.3
ENST00000438754.2
SEPT5
septin 5
chr22_+_19701985 0.53 ENST00000455784.2
ENST00000406395.1
SEPT5
septin 5
chr22_-_20104700 0.53 ENST00000439169.2
ENST00000445045.1
ENST00000404751.3
ENST00000252136.7
ENST00000403707.3
TRMT2A
tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr17_-_27278304 0.53 ENST00000577226.1
PHF12
PHD finger protein 12
chr17_-_38256973 0.53 ENST00000246672.3
NR1D1
nuclear receptor subfamily 1, group D, member 1
chr19_-_39390350 0.53 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
SIRT2
sirtuin 2
chr8_-_145331153 0.53 ENST00000377412.4
KM-PA-2
KM-PA-2 protein; Uncharacterized protein
chr6_+_42018614 0.52 ENST00000465926.1
ENST00000482432.1
TAF8
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
chr19_+_18451439 0.52 ENST00000597431.2
PGPEP1
pyroglutamyl-peptidase I
chr3_-_46735155 0.52 ENST00000318962.4
ALS2CL
ALS2 C-terminal like
chr19_-_44097188 0.52 ENST00000594374.1
L34079.2
L34079.2
chr19_-_39390440 0.52 ENST00000249396.7
ENST00000414941.1
ENST00000392081.2
SIRT2
sirtuin 2
chr19_+_49535169 0.52 ENST00000474913.1
ENST00000359342.6
CGB2
chorionic gonadotropin, beta polypeptide 2
chr17_-_27277615 0.51 ENST00000583747.1
ENST00000584236.1
PHF12
PHD finger protein 12
chr19_+_50353944 0.51 ENST00000594151.1
ENST00000600603.1
ENST00000601638.1
ENST00000221557.9
PTOV1
prostate tumor overexpressed 1
chr18_+_56530692 0.51 ENST00000588601.1
ZNF532
zinc finger protein 532
chr11_-_46722117 0.51 ENST00000311956.4
ARHGAP1
Rho GTPase activating protein 1
chr19_+_50887585 0.51 ENST00000440232.2
ENST00000601098.1
ENST00000599857.1
ENST00000593887.1
POLD1
polymerase (DNA directed), delta 1, catalytic subunit
chr11_-_62380199 0.51 ENST00000419857.1
ENST00000394773.2
EML3
echinoderm microtubule associated protein like 3
chr1_-_6761855 0.50 ENST00000426784.1
ENST00000377573.5
ENST00000377577.5
ENST00000294401.7
DNAJC11
DnaJ (Hsp40) homolog, subfamily C, member 11
chr1_+_7844312 0.50 ENST00000377541.1
PER3
period circadian clock 3
chr2_-_45165994 0.50 ENST00000444871.2
RP11-89K21.1
RP11-89K21.1
chr1_-_41487383 0.50 ENST00000302946.8
ENST00000372613.2
ENST00000439569.2
ENST00000397197.2
SLFNL1
schlafen-like 1
chr15_-_40574787 0.50 ENST00000434396.1
ANKRD63
ankyrin repeat domain 63
chr11_+_66036004 0.50 ENST00000311481.6
ENST00000527397.1
RAB1B
RAB1B, member RAS oncogene family
chr12_-_48214345 0.50 ENST00000433685.1
ENST00000447463.1
ENST00000427332.2
HDAC7
histone deacetylase 7
chr17_+_36905613 0.50 ENST00000539023.1
CTB-58E17.5
Uncharacterized protein; cDNA FLJ52623
chr4_+_159690218 0.49 ENST00000264433.6
FNIP2
folliculin interacting protein 2
chr2_+_27593389 0.49 ENST00000233575.2
ENST00000543024.1
ENST00000537606.1
SNX17
sorting nexin 17
chr1_-_161015663 0.49 ENST00000534633.1
USF1
upstream transcription factor 1
chr17_+_7210921 0.49 ENST00000573542.1
EIF5A
eukaryotic translation initiation factor 5A
chrX_+_48911090 0.49 ENST00000597275.1
CCDC120
coiled-coil domain containing 120
chr1_-_212873267 0.49 ENST00000243440.1
BATF3
basic leucine zipper transcription factor, ATF-like 3
chr12_-_6579833 0.49 ENST00000396308.3
VAMP1
vesicle-associated membrane protein 1 (synaptobrevin 1)
chr22_-_32058166 0.49 ENST00000435900.1
ENST00000336566.4
PISD
phosphatidylserine decarboxylase
chr19_+_7968728 0.49 ENST00000397981.3
ENST00000545011.1
ENST00000397983.3
ENST00000397979.3
MAP2K7
mitogen-activated protein kinase kinase 7
chr19_+_6361795 0.49 ENST00000596149.1
CLPP
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr3_-_121467983 0.48 ENST00000472475.1
GOLGB1
golgin B1
chr2_-_220117867 0.48 ENST00000456818.1
ENST00000447205.1
TUBA4A
tubulin, alpha 4a
chr3_-_197463590 0.48 ENST00000296343.5
ENST00000389665.5
ENST00000449205.1
KIAA0226
KIAA0226
chr17_+_7748233 0.48 ENST00000570632.1
KDM6B
lysine (K)-specific demethylase 6B
chr7_-_99717463 0.48 ENST00000437822.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr16_-_70719925 0.48 ENST00000338779.6
MTSS1L
metastasis suppressor 1-like
chr19_+_6361754 0.48 ENST00000597326.1
CLPP
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr19_+_36203830 0.48 ENST00000262630.3
ZBTB32
zinc finger and BTB domain containing 32
chr6_+_42018251 0.48 ENST00000372978.3
ENST00000494547.1
ENST00000456846.2
ENST00000372982.4
ENST00000472818.1
ENST00000372977.3
TAF8
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
chr19_+_54705025 0.48 ENST00000441429.1
RPS9
ribosomal protein S9
chr19_+_35759824 0.48 ENST00000343550.5
USF2
upstream transcription factor 2, c-fos interacting
chr12_-_71003568 0.48 ENST00000547715.1
ENST00000451516.2
ENST00000538708.1
ENST00000550857.1
ENST00000261266.5
PTPRB
protein tyrosine phosphatase, receptor type, B
chr2_+_237476419 0.48 ENST00000447924.1
ACKR3
atypical chemokine receptor 3
chr20_-_2821271 0.47 ENST00000448755.1
ENST00000360652.2
PCED1A
PC-esterase domain containing 1A
chr20_-_4055812 0.47 ENST00000379526.1
RP11-352D3.2
Uncharacterized protein
chr5_-_132112921 0.47 ENST00000378721.4
ENST00000378701.1
SEPT8
septin 8
chr2_-_242255117 0.47 ENST00000420451.1
ENST00000417540.1
ENST00000310931.4
HDLBP
high density lipoprotein binding protein
chr16_+_29985503 0.47 ENST00000543033.1
ENST00000279394.3
TAOK2
TAO kinase 2
chr22_+_38093005 0.47 ENST00000406386.3
TRIOBP
TRIO and F-actin binding protein
chr7_-_766879 0.47 ENST00000537384.1
ENST00000417852.1
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr17_+_42264322 0.46 ENST00000446571.3
ENST00000357984.3
ENST00000538716.2
TMUB2
transmembrane and ubiquitin-like domain containing 2
chr1_-_154946825 0.46 ENST00000368453.4
ENST00000368450.1
ENST00000366442.2
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr17_+_79373540 0.46 ENST00000307745.7
RP11-1055B8.7
BAH and coiled-coil domain-containing protein 1
chr11_-_45939565 0.46 ENST00000525192.1
ENST00000378750.5
PEX16
peroxisomal biogenesis factor 16
chr7_+_143079000 0.46 ENST00000392910.2
ZYX
zyxin
chr19_-_1021113 0.46 ENST00000333175.5
ENST00000356663.3
TMEM259
transmembrane protein 259
chr3_-_119379427 0.45 ENST00000264231.3
ENST00000468801.1
ENST00000538678.1
POPDC2
popeye domain containing 2
chr1_-_156460391 0.45 ENST00000360595.3
MEF2D
myocyte enhancer factor 2D
chr19_-_50432782 0.45 ENST00000413454.1
ENST00000596437.1
ENST00000341114.3
ENST00000595948.1
NUP62
IL4I1
nucleoporin 62kDa
interleukin 4 induced 1
chr1_-_51810778 0.45 ENST00000413473.2
ENST00000401051.3
ENST00000527205.1
TTC39A
tetratricopeptide repeat domain 39A
chr7_+_99717230 0.44 ENST00000262932.3
CNPY4
canopy FGF signaling regulator 4
chr10_-_135382876 0.44 ENST00000432597.2
ENST00000541506.1
SYCE1
SPRN
synaptonemal complex central element protein 1
shadow of prion protein homolog (zebrafish)
chr16_+_1401924 0.44 ENST00000204679.4
ENST00000529110.1
GNPTG
N-acetylglucosamine-1-phosphate transferase, gamma subunit
chr7_-_35734607 0.44 ENST00000427455.1
HERPUD2
HERPUD family member 2
chr11_-_46940074 0.44 ENST00000378623.1
ENST00000534404.1
LRP4
low density lipoprotein receptor-related protein 4
chr9_-_123342415 0.44 ENST00000349780.4
ENST00000360190.4
ENST00000360822.3
ENST00000359309.3
CDK5RAP2
CDK5 regulatory subunit associated protein 2
chr19_+_50432400 0.44 ENST00000423777.2
ENST00000600336.1
ENST00000597227.1
ATF5
activating transcription factor 5
chr19_+_4402659 0.44 ENST00000301280.5
ENST00000585854.1
CHAF1A
chromatin assembly factor 1, subunit A (p150)
chrX_-_47509887 0.43 ENST00000247161.3
ENST00000592066.1
ENST00000376983.3
ELK1
ELK1, member of ETS oncogene family
chr17_+_37793318 0.43 ENST00000336308.5
STARD3
StAR-related lipid transfer (START) domain containing 3
chr1_+_155146318 0.43 ENST00000368385.4
ENST00000545012.1
ENST00000392451.2
ENST00000368383.3
ENST00000368382.1
ENST00000334634.4
TRIM46
tripartite motif containing 46
chr3_-_52486841 0.43 ENST00000496590.1
TNNC1
troponin C type 1 (slow)
chr1_+_230202936 0.43 ENST00000366672.4
GALNT2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
chr11_+_72281681 0.43 ENST00000450804.3
RP11-169D4.1
RP11-169D4.1
chr17_-_1531635 0.43 ENST00000571650.1
SLC43A2
solute carrier family 43 (amino acid system L transporter), member 2
chr1_+_78245466 0.43 ENST00000477627.2
FAM73A
family with sequence similarity 73, member A
chr17_-_73511504 0.42 ENST00000581870.1
CASKIN2
CASK interacting protein 2
chr1_+_160321120 0.42 ENST00000424754.1
NCSTN
nicastrin
chr1_+_23037323 0.42 ENST00000544305.1
ENST00000374630.3
ENST00000400191.3
ENST00000374632.3
EPHB2
EPH receptor B2
chr12_-_56652111 0.42 ENST00000267116.7
ANKRD52
ankyrin repeat domain 52
chr17_+_2240775 0.42 ENST00000268989.3
ENST00000426855.2
SGSM2
small G protein signaling modulator 2
chr12_-_57634475 0.42 ENST00000393825.1
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr21_-_46707793 0.42 ENST00000331343.7
ENST00000349485.5
POFUT2
protein O-fucosyltransferase 2
chr5_+_133861790 0.42 ENST00000395003.1
PHF15
jade family PHD finger 2
chr19_+_4304685 0.42 ENST00000601006.1
FSD1
fibronectin type III and SPRY domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of RXRG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.5 1.5 GO:0070446 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.4 1.3 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.4 3.3 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.4 1.4 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.3 1.0 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.3 0.9 GO:1901207 regulation of heart looping(GO:1901207)
0.3 1.6 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.3 1.6 GO:0032954 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.3 0.8 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.2 1.7 GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.2 0.2 GO:1900200 mesenchymal cell apoptotic process involved in metanephros development(GO:1900200) regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900211) negative regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900212)
0.2 1.4 GO:0072069 ascending thin limb development(GO:0072021) DCT cell differentiation(GO:0072069) metanephric ascending thin limb development(GO:0072218) metanephric DCT cell differentiation(GO:0072240)
0.2 1.4 GO:1903588 regulation of neural retina development(GO:0061074) negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.2 1.1 GO:2000470 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.2 0.4 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.2 1.0 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.2 0.8 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.2 0.7 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.2 0.5 GO:0060086 circadian temperature homeostasis(GO:0060086)
0.2 0.5 GO:0031448 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.2 0.5 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.2 1.6 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.2 0.8 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.2 0.9 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.2 1.2 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.1 0.4 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 0.7 GO:1901536 negative regulation of DNA demethylation(GO:1901536)
0.1 0.6 GO:2000342 regulation of muscle hyperplasia(GO:0014738) negative regulation of muscle hyperplasia(GO:0014740) negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1 0.1 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.1 0.6 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.1 0.4 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.1 0.4 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.1 0.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.5 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 0.7 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.1 0.4 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.1 0.6 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.1 0.3 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.1 0.4 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.1 0.6 GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.1 0.3 GO:0060927 Purkinje myocyte differentiation(GO:0003168) cardiac pacemaker cell fate commitment(GO:0060927) atrioventricular node cell fate commitment(GO:0060929)
0.1 0.8 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.1 0.4 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.1 0.3 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.3 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.1 0.7 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.1 0.4 GO:0042351 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.1 0.3 GO:0071879 UDP-glucose catabolic process(GO:0006258) positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1 0.6 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.1 0.4 GO:0051413 response to cortisone(GO:0051413)
0.1 0.7 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.5 GO:1903911 positive regulation of postsynaptic membrane organization(GO:1901628) positive regulation of receptor clustering(GO:1903911)
0.1 0.4 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 1.0 GO:0035897 proteolysis in other organism(GO:0035897)
0.1 0.4 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.5 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.4 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.1 0.3 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.1 0.7 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 0.3 GO:1904815 negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.1 1.1 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.1 0.3 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 0.3 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.1 1.0 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.9 GO:1902414 protein localization to cell junction(GO:1902414)
0.1 0.5 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.1 0.3 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.1 0.8 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.1 0.2 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.3 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1 0.5 GO:0030047 actin modification(GO:0030047)
0.1 0.5 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1 0.2 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.1 0.2 GO:0099558 maintenance of synapse structure(GO:0099558)
0.1 0.6 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.3 GO:0002432 granuloma formation(GO:0002432)
0.1 1.0 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.1 0.2 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.1 0.4 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1 0.5 GO:0060992 response to fungicide(GO:0060992)
0.1 0.2 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.1 0.3 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.1 0.2 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.1 0.7 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 0.3 GO:0006601 creatine biosynthetic process(GO:0006601)
0.1 0.2 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.1 0.4 GO:0097473 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 0.2 GO:0032242 regulation of nucleoside transport(GO:0032242)
0.1 1.4 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.3 GO:0060161 positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.1 0.6 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 1.0 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 1.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.7 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.1 0.3 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.1 0.6 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 0.3 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.1 0.2 GO:1904116 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.1 0.2 GO:0033058 directional locomotion(GO:0033058)
0.1 0.3 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 0.2 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.0 0.1 GO:1902822 cleavage furrow ingression(GO:0036090) regulation of late endosome to lysosome transport(GO:1902822) positive regulation of late endosome to lysosome transport(GO:1902824)
0.0 0.4 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.0 0.2 GO:0044571 [2Fe-2S] cluster assembly(GO:0044571)
0.0 0.4 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.3 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.2 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.4 GO:0099612 protein localization to axon(GO:0099612)
0.0 0.7 GO:0030238 male sex determination(GO:0030238)
0.0 0.5 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.3 GO:1901216 positive regulation of neuron death(GO:1901216)
0.0 1.0 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.5 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.5 GO:0006570 tyrosine metabolic process(GO:0006570)
0.0 0.4 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.0 0.7 GO:0014029 neural crest formation(GO:0014029)
0.0 0.2 GO:0071503 response to heparin(GO:0071503)
0.0 0.4 GO:0009227 UDP-N-acetylglucosamine catabolic process(GO:0006049) nucleotide-sugar catabolic process(GO:0009227)
0.0 0.3 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.2 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.7 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.7 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.4 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.1 GO:1903450 regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452)
0.0 0.5 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
0.0 0.5 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.1 GO:0000494 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.0 0.4 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.3 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.3 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.4 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.3 GO:1904526 regulation of microtubule binding(GO:1904526)
0.0 0.6 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.3 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.4 GO:0035608 protein deglutamylation(GO:0035608)
0.0 0.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.4 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.2 GO:1902045 negative regulation of Fas signaling pathway(GO:1902045)
0.0 0.2 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0 1.1 GO:0045730 respiratory burst(GO:0045730)
0.0 0.1 GO:0070318 response to anoxia(GO:0034059) positive regulation of G0 to G1 transition(GO:0070318)
0.0 0.5 GO:0007512 adult heart development(GO:0007512)
0.0 0.4 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.8 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.3 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.2 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.2 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.7 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.3 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.2 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.2 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0 1.6 GO:0033572 transferrin transport(GO:0033572)
0.0 0.2 GO:1900024 regulation of substrate adhesion-dependent cell spreading(GO:1900024) positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.3 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.4 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.3 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 0.2 GO:0072402 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0 0.5 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.3 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.4 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.3 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.1 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.2 GO:0031047 gene silencing by RNA(GO:0031047)
0.0 0.4 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.3 GO:0007416 synapse assembly(GO:0007416)
0.0 0.1 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.0 0.1 GO:0032796 uropod organization(GO:0032796)
0.0 0.8 GO:0030728 ovulation(GO:0030728)
0.0 0.2 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.7 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.1 GO:0061056 sclerotome development(GO:0061056)
0.0 1.0 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.1 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.4 GO:0016573 histone acetylation(GO:0016573) internal peptidyl-lysine acetylation(GO:0018393)
0.0 0.3 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.1 GO:0033037 polysaccharide localization(GO:0033037)
0.0 0.1 GO:0035617 stress granule disassembly(GO:0035617)
0.0 0.1 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.5 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.2 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.4 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.3 GO:1900825 regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.0 0.4 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.0 0.4 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.4 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.2 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.3 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.3 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.4 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.4 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:0021794 thalamus development(GO:0021794)
0.0 0.4 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.1 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.0 0.2 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.6 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.1 GO:0098712 L-glutamate import across plasma membrane(GO:0098712)
0.0 0.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.5 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.3 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.2 GO:0031274 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.3 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 0.2 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.2 GO:0022900 electron transport chain(GO:0022900)
0.0 0.2 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 1.0 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.5 GO:0030220 platelet formation(GO:0030220)
0.0 0.2 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.4 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.4 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.3 GO:1903020 positive regulation of glycoprotein metabolic process(GO:1903020)
0.0 0.7 GO:0032402 melanosome transport(GO:0032402)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.5 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.3 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.1 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.4 GO:0043586 tongue development(GO:0043586)
0.0 0.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.2 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.0 0.0 GO:0046984 regulation of hemoglobin biosynthetic process(GO:0046984)
0.0 0.3 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.1 GO:0015862 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.0 0.5 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.8 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.6 GO:0001893 maternal placenta development(GO:0001893)
0.0 0.2 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.5 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.2 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.0 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.0 0.2 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.3 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.3 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.1 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.1 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.0 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.4 GO:0032011 ARF protein signal transduction(GO:0032011)
0.0 0.5 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.2 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.4 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.2 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.0 0.1 GO:0036100 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.4 2.2 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.3 4.4 GO:0005642 annulate lamellae(GO:0005642)
0.3 0.3 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.2 0.7 GO:0044306 neuron projection terminus(GO:0044306)
0.2 0.6 GO:0031523 Myb complex(GO:0031523)
0.1 0.8 GO:0000801 central element(GO:0000801)
0.1 0.5 GO:0043293 apoptosome(GO:0043293)
0.1 1.7 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.0 GO:0070435 Shc-EGFR complex(GO:0070435)
0.1 1.5 GO:0072687 meiotic spindle(GO:0072687)
0.1 0.6 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 1.1 GO:0032010 phagolysosome(GO:0032010)
0.1 0.4 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.4 GO:0044301 climbing fiber(GO:0044301)
0.1 0.2 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.1 0.9 GO:0016589 NURF complex(GO:0016589)
0.1 0.3 GO:0043257 laminin-8 complex(GO:0043257)
0.1 1.3 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 0.9 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 1.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.3 GO:0045160 myosin I complex(GO:0045160)
0.1 0.3 GO:1990742 microvesicle(GO:1990742)
0.1 0.4 GO:1990769 proximal neuron projection(GO:1990769)
0.1 0.4 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.6 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 1.0 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.5 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.7 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.2 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 0.5 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.5 GO:0001739 sex chromatin(GO:0001739)
0.0 0.2 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.5 GO:0097443 sorting endosome(GO:0097443)
0.0 0.5 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.7 GO:0005869 dynactin complex(GO:0005869)
0.0 0.8 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.6 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.4 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.1 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.6 GO:0016600 flotillin complex(GO:0016600)
0.0 0.4 GO:0005638 lamin filament(GO:0005638)
0.0 0.3 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.4 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.4 GO:0016342 catenin complex(GO:0016342)
0.0 1.7 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.2 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.2 GO:0097513 myosin II filament(GO:0097513)
0.0 0.2 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 1.1 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.7 GO:0016460 myosin II complex(GO:0016460)
0.0 0.5 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 1.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 1.0 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0097635 Atg12-Atg5-Atg16 complex(GO:0034274) extrinsic component of autophagosome membrane(GO:0097635)
0.0 2.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.2 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279) symmetric synapse(GO:0032280)
0.0 0.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.4 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.4 GO:0030897 HOPS complex(GO:0030897)
0.0 1.4 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.8 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.3 GO:0090543 Flemming body(GO:0090543)
0.0 0.5 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.3 GO:0097433 dense body(GO:0097433)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.5 GO:0031201 SNARE complex(GO:0031201)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.9 GO:0005844 polysome(GO:0005844)
0.0 0.2 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.5 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 1.5 GO:0031672 A band(GO:0031672)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.1 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.1 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 0.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.2 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.2 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 1.1 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 2.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.2 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.6 GO:0008305 integrin complex(GO:0008305)
0.0 1.5 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.1 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 1.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.7 GO:0043679 axon terminus(GO:0043679)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0034709 methylosome(GO:0034709)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.3 1.0 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.2 2.6 GO:0071532 ankyrin repeat binding(GO:0071532)
0.2 0.9 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.2 1.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.2 1.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.2 0.6 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.2 1.6 GO:1990932 5.8S rRNA binding(GO:1990932)
0.2 0.6 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.2 1.0 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.2 0.5 GO:0004730 pseudouridylate synthase activity(GO:0004730)
0.2 3.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.2 1.7 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.4 GO:0061714 folic acid receptor activity(GO:0061714)
0.1 0.6 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 1.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.4 GO:0004326 tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841)
0.1 1.0 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 0.4 GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617)
0.1 1.0 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 0.4 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.4 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.3 GO:0090541 MIT domain binding(GO:0090541)
0.1 0.7 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 0.3 GO:0080101 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.1 0.6 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.7 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.7 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.2 GO:0036033 mediator complex binding(GO:0036033)
0.1 0.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.4 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 1.0 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.7 GO:0070097 delta-catenin binding(GO:0070097)
0.1 1.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.3 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.2 GO:0070984 SET domain binding(GO:0070984)
0.1 0.2 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 0.4 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.1 0.4 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.1 0.2 GO:0052830 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.1 0.3 GO:0010736 serum response element binding(GO:0010736)
0.1 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.4 GO:0031013 troponin I binding(GO:0031013)
0.1 1.1 GO:0016176 superoxide-generating NADPH oxidase activity(GO:0016175) superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.5 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 1.4 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.4 GO:0016936 galactoside binding(GO:0016936)
0.1 2.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.2 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 0.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.4 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.1 1.5 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 1.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 1.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.3 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.5 GO:0016494 C-X-C chemokine receptor activity(GO:0016494) C-X-C chemokine binding(GO:0019958)
0.0 1.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.7 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.4 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0004560 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.0 0.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.4 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.0 0.4 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.1 GO:0036009 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.2 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 1.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.5 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.5 GO:0045159 myosin II binding(GO:0045159)
0.0 0.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.4 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 1.0 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.2 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.5 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.3 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 1.7 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.4 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.2 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.0 0.3 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 1.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.3 GO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679)
0.0 0.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.4 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.3 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.2 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.6 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.7 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 1.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.4 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.5 GO:0048185 activin binding(GO:0048185)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.3 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.8 GO:0005123 death receptor binding(GO:0005123)
0.0 0.4 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.6 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.7 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 0.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.3 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.6 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.2 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.3 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0097258 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 1.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.5 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.8 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0050659 chondroitin 4-sulfotransferase activity(GO:0047756) N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.0 0.6 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 1.0 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.9 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0016866 intramolecular transferase activity(GO:0016866)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.0 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.6 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.3 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.3 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.9 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 1.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.0 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 2.0 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.6 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 1.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.5 PID IGF1 PATHWAY IGF1 pathway
0.0 0.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.7 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.4 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 1.9 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.1 PID ATM PATHWAY ATM pathway
0.0 0.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.5 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.2 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.8 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.6 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.5 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 2.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.7 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.6 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.3 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.3 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.6 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.2 1.4 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.1 2.5 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 1.1 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 3.5 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 1.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 1.2 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.9 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.5 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.6 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 1.6 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 1.0 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 1.9 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 1.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 1.1 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 1.0 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 2.3 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 2.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.9 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.6 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.9 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.3 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 1.0 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 1.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.7 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.4 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.1 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.4 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.6 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.9 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.6 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.7 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.7 REACTOME IL 3 5 AND GM CSF SIGNALING Genes involved in Interleukin-3, 5 and GM-CSF signaling