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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SOX11

Z-value: 0.47

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Transcription factors associated with SOX11

Gene Symbol Gene ID Gene Info
ENSG00000176887.5 SRY-box transcription factor 11

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX11hg19_v2_chr2_+_5832799_58327990.691.3e-01Click!

Activity profile of SOX11 motif

Sorted Z-values of SOX11 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_86534822 0.38 ENST00000445770.2
Uncharacterized protein
chr6_-_116381918 0.30 ENST00000606080.1
fyn-related kinase
chr8_-_25281747 0.28 ENST00000421054.2
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr6_-_32977345 0.26 ENST00000450833.2
ENST00000374813.1
ENST00000229829.5
major histocompatibility complex, class II, DO alpha
chr2_+_138722028 0.22 ENST00000280096.5
histamine N-methyltransferase
chr4_+_110749143 0.21 ENST00000317735.4
retinal pigment epithelium-derived rhodopsin homolog
chr1_-_219615984 0.19 ENST00000420762.1
RP11-95P13.1
chr4_-_90759440 0.18 ENST00000336904.3
synuclein, alpha (non A4 component of amyloid precursor)
chrX_-_109590174 0.18 ENST00000372054.1
guanine nucleotide binding protein (G protein), gamma 5 pseudogene 2
chr5_+_175085033 0.16 ENST00000377291.2
histamine receptor H2
chr6_-_88001706 0.16 ENST00000369576.2
gap junction protein, beta 7, 25kDa
chr4_+_71019903 0.16 ENST00000344526.5
chromosome 4 open reading frame 40
chr7_+_66800928 0.15 ENST00000430244.1
RP11-166O4.5
chr6_+_26183958 0.15 ENST00000356530.3
histone cluster 1, H2be
chr2_+_179318295 0.15 ENST00000442710.1
deafness, autosomal recessive 59
chr2_-_178128149 0.15 ENST00000423513.1
nuclear factor, erythroid 2-like 2
chr10_-_25305011 0.15 ENST00000331161.4
ENST00000376363.1
enkurin, TRPC channel interacting protein
chr17_+_47448102 0.14 ENST00000576461.1
Uncharacterized protein
chr20_+_32250079 0.14 ENST00000375222.3
chromosome 20 open reading frame 144
chr7_-_56118981 0.14 ENST00000419984.2
ENST00000413218.1
ENST00000424596.1
phosphoserine phosphatase
chrX_+_23928500 0.14 ENST00000435707.1
chromosome X open reading frame 58
chr18_+_22040593 0.14 ENST00000256906.4
histamine receptor H4
chr4_+_169013666 0.14 ENST00000359299.3
annexin A10
chr6_-_56492816 0.13 ENST00000522360.1
dystonin
chr12_+_70574088 0.13 ENST00000552324.1
RP11-320P7.2
chr5_+_140248518 0.13 ENST00000398640.2
protocadherin alpha 11
chr8_+_55466915 0.12 ENST00000522711.2
RP11-53M11.3
chr20_-_5426380 0.12 ENST00000609252.1
ENST00000422352.1
long intergenic non-protein coding RNA 658
chr2_-_225266802 0.12 ENST00000243806.2
family with sequence similarity 124B
chr4_+_183065793 0.12 ENST00000512480.1
teneurin transmembrane protein 3
chrY_+_14958970 0.12 ENST00000453031.1
ubiquitin specific peptidase 9, Y-linked
chr13_-_30424821 0.11 ENST00000380680.4
ubiquitin-like 3
chr13_-_45048386 0.11 ENST00000472477.1
TSC22 domain family, member 1
chr12_-_122240792 0.10 ENST00000545885.1
ENST00000542933.1
ENST00000428029.2
ENST00000541694.1
ENST00000536662.1
ENST00000535643.1
ENST00000541657.1
AC084018.1
ras homolog family member F (in filopodia)
chr5_+_71403280 0.09 ENST00000511641.2
microtubule-associated protein 1B
chr6_-_30585009 0.09 ENST00000376511.2
protein phosphatase 1, regulatory subunit 10
chr16_+_67261008 0.09 ENST00000304800.9
ENST00000563953.1
ENST00000565201.1
transmembrane protein 208
chr20_-_30539773 0.09 ENST00000202017.4
p53 and DNA-damage regulated 1
chrX_-_132231123 0.09 ENST00000511190.1
ubiquitin specific peptidase 26
chr21_+_43619796 0.08 ENST00000398457.2
ATP-binding cassette, sub-family G (WHITE), member 1
chr9_+_27109133 0.08 ENST00000519097.1
ENST00000380036.4
TEK tyrosine kinase, endothelial
chr4_+_159727222 0.08 ENST00000512986.1
folliculin interacting protein 2
chrX_+_135388147 0.08 ENST00000394141.1
G protein-coupled receptor 112
chrX_+_107288197 0.08 ENST00000415430.3
V-set and immunoglobulin domain containing 1
chr6_+_159071015 0.08 ENST00000360448.3
synaptotagmin-like 3
chr1_+_146373546 0.08 ENST00000446760.2
neuroblastoma breakpoint family, member 12
chr17_-_6524159 0.07 ENST00000589033.1
KIAA0753
chr10_-_90611566 0.07 ENST00000371930.4
ankyrin repeat domain 22
chr11_-_64684672 0.07 ENST00000377264.3
ENST00000421419.2
autophagy related 2A
chr15_+_69857515 0.07 ENST00000559477.1
RP11-279F6.1
chr11_+_92085262 0.07 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT atypical cadherin 3
chrX_+_107288239 0.07 ENST00000217957.5
V-set and immunoglobulin domain containing 1
chr10_-_95241951 0.07 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
myoferlin
chr7_-_82792215 0.07 ENST00000333891.9
ENST00000423517.2
piccolo presynaptic cytomatrix protein
chr8_+_9413410 0.06 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr10_-_5446786 0.06 ENST00000479328.1
ENST00000380419.3
tubulin, alpha-like 3
chr2_+_207804278 0.06 ENST00000272852.3
carboxypeptidase O
chr10_-_95242044 0.06 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
myoferlin
chr15_-_37392086 0.06 ENST00000561208.1
Meis homeobox 2
chr1_+_214776516 0.06 ENST00000366955.3
centromere protein F, 350/400kDa
chr3_+_69812701 0.06 ENST00000472437.1
microphthalmia-associated transcription factor
chr8_-_13134045 0.06 ENST00000512044.2
deleted in liver cancer 1
chr10_-_25304889 0.06 ENST00000483339.2
enkurin, TRPC channel interacting protein
chr15_-_79383102 0.05 ENST00000558480.2
ENST00000419573.3
Ras protein-specific guanine nucleotide-releasing factor 1
chr5_+_108083517 0.05 ENST00000281092.4
ENST00000536402.1
fer (fps/fes related) tyrosine kinase
chr8_-_37707356 0.05 ENST00000520601.1
ENST00000521170.1
ENST00000220659.6
BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
chr7_-_112635675 0.05 ENST00000447785.1
ENST00000451962.1
AC018464.3
chr11_+_12399071 0.05 ENST00000539723.1
ENST00000550549.1
parvin, alpha
chr2_-_73869508 0.05 ENST00000272425.3
N-acetyltransferase 8 (GCN5-related, putative)
chr19_+_50094866 0.05 ENST00000418929.2
proline rich 12
chr1_+_149239529 0.05 ENST00000457216.2
RP11-403I13.4
chr17_+_6347729 0.05 ENST00000572447.1
family with sequence similarity 64, member A
chr19_-_5680499 0.05 ENST00000587589.1
chromosome 19 open reading frame 70
chr15_+_99433570 0.05 ENST00000558898.1
insulin-like growth factor 1 receptor
chr6_+_30585486 0.05 ENST00000259873.4
ENST00000506373.2
mitochondrial ribosomal protein S18B
chrX_+_27826107 0.05 ENST00000356790.2
melanoma antigen family B, 10
chr12_+_56075330 0.05 ENST00000394252.3
methyltransferase like 7B
chr15_-_99791413 0.04 ENST00000394129.2
ENST00000558663.1
ENST00000394135.3
ENST00000561365.1
ENST00000560279.1
tetratricopeptide repeat domain 23
chr2_-_225266711 0.04 ENST00000389874.3
family with sequence similarity 124B
chr3_-_57678772 0.04 ENST00000311128.5
DENN/MADD domain containing 6A
chr8_-_54752406 0.04 ENST00000520188.1
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr22_+_24407776 0.04 ENST00000405822.2
calcineurin binding protein 1
chr20_-_32308028 0.04 ENST00000409299.3
ENST00000217398.3
ENST00000344022.3
peroxisomal membrane protein 4, 24kDa
chr9_+_22646189 0.04 ENST00000436786.1
RP11-399D6.2
chr3_-_47950745 0.04 ENST00000429422.1
microtubule-associated protein 4
chr4_+_141294628 0.04 ENST00000512749.1
ENST00000608372.1
ENST00000506597.1
ENST00000394201.4
ENST00000510586.1
short coiled-coil protein
chr12_-_122879969 0.04 ENST00000540304.1
CAP-GLY domain containing linker protein 1
chr2_+_109237717 0.04 ENST00000409441.1
LIM and senescent cell antigen-like domains 1
chr2_-_37501692 0.04 ENST00000443977.1
protein kinase D3
chr5_+_173472607 0.04 ENST00000303177.3
ENST00000519867.1
Neuron-specific protein family member 2
chr4_-_105416039 0.04 ENST00000394767.2
CXXC finger protein 4
chr11_+_4664650 0.04 ENST00000396952.5
olfactory receptor, family 51, subfamily E, member 1
chr12_+_60058458 0.03 ENST00000548610.1
solute carrier family 16 (monocarboxylate transporter), member 7
chr6_-_133055815 0.03 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
vanin 3
chr10_+_86184676 0.03 ENST00000543283.1
coiled-coil serine-rich protein 2
chr9_-_21142144 0.03 ENST00000380229.2
interferon, omega 1
chr12_-_772901 0.03 ENST00000305108.4
ninjurin 2
chr17_+_6347761 0.03 ENST00000250056.8
ENST00000571373.1
ENST00000570337.2
ENST00000572595.2
ENST00000576056.1
family with sequence similarity 64, member A
chr12_+_32655048 0.03 ENST00000427716.2
ENST00000266482.3
FYVE, RhoGEF and PH domain containing 4
chr2_+_27799389 0.03 ENST00000408964.2
chromosome 2 open reading frame 16
chr1_+_65730385 0.03 ENST00000263441.7
ENST00000395325.3
DnaJ (Hsp40) homolog, subfamily C, member 6
chr4_+_72204755 0.03 ENST00000512686.1
ENST00000340595.3
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
chr17_-_10017864 0.03 ENST00000323816.4
growth arrest-specific 7
chr2_-_71222466 0.03 ENST00000606025.1
Uncharacterized protein
chr5_+_148521454 0.03 ENST00000508983.1
actin binding LIM protein family, member 3
chr5_+_172571445 0.03 ENST00000231668.9
ENST00000351486.5
ENST00000352523.6
ENST00000393770.4
BCL2/adenovirus E1B 19kDa interacting protein 1
chr7_-_35013217 0.03 ENST00000446375.1
dpy-19-like 1 (C. elegans)
chr4_-_71532207 0.03 ENST00000543780.1
ENST00000391614.3
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr18_+_46065393 0.03 ENST00000256413.3
CBP80/20-dependent translation initiation factor
chr17_+_38474489 0.03 ENST00000394089.2
ENST00000425707.3
retinoic acid receptor, alpha
chrX_-_100548045 0.03 ENST00000372907.3
ENST00000372905.2
TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
chr1_+_149754227 0.03 ENST00000444948.1
ENST00000369168.4
Fc fragment of IgG, high affinity Ia, receptor (CD64)
chr17_+_67590125 0.03 ENST00000591334.1
AC003051.1
chrX_+_24483338 0.03 ENST00000379162.4
ENST00000441463.2
pyruvate dehydrogenase kinase, isozyme 3
chr14_+_96949319 0.03 ENST00000554706.1
adenylate kinase 7
chr18_-_67614645 0.03 ENST00000577287.1
CD226 molecule
chr3_-_18466026 0.02 ENST00000417717.2
SATB homeobox 1
chr19_-_14911023 0.02 ENST00000248073.2
olfactory receptor, family 7, subfamily C, member 1
chr5_+_179159813 0.02 ENST00000292599.3
mastermind-like 1 (Drosophila)
chr13_-_99630233 0.02 ENST00000376460.1
ENST00000442173.1
dedicator of cytokinesis 9
chr4_-_22444733 0.02 ENST00000508133.1
G protein-coupled receptor 125
chr5_-_115872124 0.02 ENST00000515009.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr6_+_131958436 0.02 ENST00000357639.3
ENST00000543135.1
ENST00000427148.2
ENST00000358229.5
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr18_+_46065483 0.02 ENST00000382998.4
CBP80/20-dependent translation initiation factor
chr4_-_73434498 0.02 ENST00000286657.4
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr15_+_80733570 0.02 ENST00000533983.1
ENST00000527771.1
ENST00000525103.1
aryl-hydrocarbon receptor nuclear translocator 2
chrX_-_13835147 0.02 ENST00000493677.1
ENST00000355135.2
glycoprotein M6B
chr3_+_112930387 0.02 ENST00000485230.1
BOC cell adhesion associated, oncogene regulated
chr21_+_17792672 0.02 ENST00000602620.1
long intergenic non-protein coding RNA 478
chr2_-_176046391 0.02 ENST00000392541.3
ENST00000409194.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr5_+_140207536 0.02 ENST00000529310.1
ENST00000527624.1
protocadherin alpha 6
chr16_+_67381263 0.01 ENST00000541146.1
ENST00000563189.1
ENST00000290940.7
leucine rich repeat containing 36
chr4_+_95972822 0.01 ENST00000509540.1
ENST00000440890.2
bone morphogenetic protein receptor, type IB
chr19_+_51774540 0.01 ENST00000600813.1
CTD-3187F8.11
chr5_+_53813536 0.01 ENST00000343017.6
ENST00000381410.4
ENST00000326277.3
sorting nexin 18
chr9_+_12775011 0.01 ENST00000319264.3
leucine rich adaptor protein 1-like
chr6_-_49712123 0.01 ENST00000263045.4
cysteine-rich secretory protein 3
chr10_-_127505167 0.01 ENST00000368786.1
uroporphyrinogen III synthase
chr3_+_113616317 0.01 ENST00000440446.2
ENST00000488680.1
GRAM domain containing 1C
chr9_+_71986182 0.01 ENST00000303068.7
family with sequence similarity 189, member A2
chr9_-_95166841 0.01 ENST00000262551.4
osteoglycin
chr1_+_198608146 0.01 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
protein tyrosine phosphatase, receptor type, C
chr5_+_140753444 0.01 ENST00000517434.1
protocadherin gamma subfamily A, 6
chr2_+_102928009 0.01 ENST00000404917.2
ENST00000447231.1
interleukin 1 receptor-like 1
chr7_-_143579973 0.01 ENST00000460532.1
ENST00000491908.1
family with sequence similarity 115, member A
chr5_-_115872142 0.01 ENST00000510263.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr2_+_102927962 0.01 ENST00000233954.1
ENST00000393393.3
ENST00000410040.1
interleukin 1 receptor-like 1
interleukin 18 receptor 1
chr12_-_15865844 0.01 ENST00000543612.1
epidermal growth factor receptor pathway substrate 8
chr8_-_623547 0.01 ENST00000522893.1
glutamate-rich 1
chr6_+_53883708 0.01 ENST00000514921.1
ENST00000274897.5
ENST00000370877.2
muscular LMNA-interacting protein
chr3_+_101504200 0.01 ENST00000422132.1
neurexophilin and PC-esterase domain family, member 3
chr1_+_154193643 0.01 ENST00000456325.1
ubiquitin associated protein 2-like
chr2_-_178128199 0.01 ENST00000449627.1
nuclear factor, erythroid 2-like 2
chr14_-_36789865 0.01 ENST00000416007.4
MAP3K12 binding inhibitory protein 1
chr2_-_145275828 0.01 ENST00000392861.2
ENST00000409211.1
zinc finger E-box binding homeobox 2
chr13_+_76413852 0.01 ENST00000533809.2
LIM domain 7
chr5_+_81601166 0.01 ENST00000439350.1
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr5_+_148521381 0.01 ENST00000504238.1
actin binding LIM protein family, member 3
chr14_-_92198403 0.00 ENST00000553329.1
ENST00000256343.3
catsper channel auxiliary subunit beta
chr6_-_136610911 0.00 ENST00000530767.1
ENST00000527759.1
ENST00000527536.1
ENST00000529826.1
ENST00000531224.1
ENST00000353331.4
BCL2-associated transcription factor 1
chr17_-_72772462 0.00 ENST00000582870.1
ENST00000581136.1
ENST00000357814.3
ENST00000579218.1
ENST00000583476.1
ENST00000580301.1
ENST00000583757.1
ENST00000582524.1
N-acetyltransferase 9 (GCN5-related, putative)
chr6_-_36515177 0.00 ENST00000229812.7
serine/threonine kinase 38
chr11_-_118047376 0.00 ENST00000278947.5
sodium channel, voltage-gated, type II, beta subunit
chr17_-_47786375 0.00 ENST00000511657.1
solute carrier family 35, member B1
chr17_-_79895097 0.00 ENST00000402252.2
ENST00000583564.1
ENST00000585244.1
ENST00000337943.5
ENST00000579698.1
pyrroline-5-carboxylate reductase 1
chr2_+_42104692 0.00 ENST00000398796.2
ENST00000442214.1
AC104654.1
chr1_-_150669604 0.00 ENST00000427665.1
ENST00000540514.1
golgi phosphoprotein 3-like
chr2_+_105050794 0.00 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
long intergenic non-protein coding RNA 1102
chrX_-_7895755 0.00 ENST00000444736.1
ENST00000537427.1
ENST00000442940.1
patatin-like phospholipase domain containing 4
chr17_-_79895154 0.00 ENST00000405481.4
ENST00000585215.1
ENST00000577624.1
ENST00000403172.4
pyrroline-5-carboxylate reductase 1
chr1_-_115292591 0.00 ENST00000438362.2
cold shock domain containing E1, RNA-binding

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX11

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.1 0.3 GO:1990637 response to prolactin(GO:1990637) regulation of ovarian follicle development(GO:2000354)
0.0 0.2 GO:0051622 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.1 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.0 0.2 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.1 GO:1901377 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.1 GO:0050904 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) diapedesis(GO:0050904)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.0 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.1 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.3 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.0 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.0 GO:0005132 type I interferon receptor binding(GO:0005132)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.2 REACTOME OPSINS Genes involved in Opsins