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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SOX7

Z-value: 0.74

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Transcription factors associated with SOX7

Gene Symbol Gene ID Gene Info
SOX7
ENSG00000171056.6 SRY-box transcription factor 7
SOX7
ENSG00000258724.1 SRY-box transcription factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX7hg19_v2_chr8_-_10588010_10588030-0.621.9e-01Click!

Activity profile of SOX7 motif

Sorted Z-values of SOX7 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_34144411 0.52 ENST00000382375.4
ENST00000453404.1
ENST00000382378.1
ENST00000477513.1
C21orf49
chromosome 21 open reading frame 49
chr14_+_101361107 0.43 ENST00000553584.1
ENST00000554852.1
MEG8
maternally expressed 8 (non-protein coding)
chr15_+_59439899 0.39 ENST00000599727.1
C15ORF31
C15ORF31
chr2_-_152118276 0.38 ENST00000409092.1
RBM43
RNA binding motif protein 43
chr6_+_168434678 0.29 ENST00000496008.1
KIF25
kinesin family member 25
chr19_-_21950332 0.27 ENST00000598026.1
ZNF100
zinc finger protein 100
chr1_+_10509971 0.25 ENST00000320498.4
CORT
cortistatin
chr16_+_22518495 0.25 ENST00000541154.1
NPIPB5
nuclear pore complex interacting protein family, member B5
chr12_-_57443886 0.23 ENST00000300119.3
MYO1A
myosin IA
chr19_-_38916839 0.23 ENST00000433821.2
ENST00000426920.2
ENST00000587753.1
ENST00000454404.2
ENST00000293062.9
RASGRP4
RAS guanyl releasing protein 4
chr19_-_5784610 0.21 ENST00000390672.2
ENST00000419421.2
PRR22
proline rich 22
chr10_-_71169031 0.20 ENST00000373307.1
TACR2
tachykinin receptor 2
chr17_-_28661065 0.19 ENST00000328886.4
ENST00000538566.2
TMIGD1
transmembrane and immunoglobulin domain containing 1
chr8_+_74271144 0.16 ENST00000519134.1
ENST00000518355.1
RP11-434I12.3
RP11-434I12.3
chr6_-_111804905 0.16 ENST00000358835.3
ENST00000435970.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr5_-_95158644 0.16 ENST00000237858.6
GLRX
glutaredoxin (thioltransferase)
chr15_+_75639372 0.15 ENST00000566313.1
ENST00000568059.1
ENST00000568881.1
NEIL1
nei endonuclease VIII-like 1 (E. coli)
chr17_-_39623681 0.14 ENST00000225899.3
KRT32
keratin 32
chrY_+_14813160 0.14 ENST00000338981.3
USP9Y
ubiquitin specific peptidase 9, Y-linked
chr10_+_5005445 0.13 ENST00000380872.4
AKR1C1
aldo-keto reductase family 1, member C1
chr1_+_100598742 0.13 ENST00000370139.1
TRMT13
tRNA methyltransferase 13 homolog (S. cerevisiae)
chr9_-_70465758 0.13 ENST00000489273.1
CBWD5
COBW domain containing 5
chr11_+_3011093 0.12 ENST00000332881.2
AC131971.1
HCG1782999; PRO0943; Uncharacterized protein
chr19_+_42349092 0.12 ENST00000269945.3
ENST00000596258.1
DMRTC2
DMRT-like family C2
chr10_-_17243579 0.11 ENST00000525762.1
ENST00000412821.3
ENST00000351358.4
ENST00000377766.5
ENST00000358282.7
ENST00000488990.1
ENST00000377799.3
TRDMT1
tRNA aspartic acid methyltransferase 1
chr4_-_47983519 0.10 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
CNGA1
cyclic nucleotide gated channel alpha 1
chr2_-_190445499 0.10 ENST00000261024.2
SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr10_+_24738355 0.10 ENST00000307544.6
KIAA1217
KIAA1217
chr1_-_43751230 0.10 ENST00000523677.1
C1orf210
chromosome 1 open reading frame 210
chr6_+_42531798 0.10 ENST00000372903.2
ENST00000372899.1
ENST00000372901.1
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr5_-_95158375 0.10 ENST00000512469.2
ENST00000379979.4
ENST00000505427.1
ENST00000508780.1
GLRX
glutaredoxin (thioltransferase)
chr18_+_32820990 0.09 ENST00000601719.1
ENST00000591206.1
ENST00000330501.7
ENST00000261333.6
ENST00000355632.4
ENST00000585800.1
ZNF397
zinc finger protein 397
chr19_+_37837218 0.09 ENST00000591134.1
HKR1
HKR1, GLI-Kruppel zinc finger family member
chr1_-_89738458 0.09 ENST00000443807.1
GBP5
guanylate binding protein 5
chr6_+_150690028 0.08 ENST00000229447.5
ENST00000344419.3
IYD
iodotyrosine deiodinase
chr12_-_57328187 0.08 ENST00000293502.1
SDR9C7
short chain dehydrogenase/reductase family 9C, member 7
chr1_+_156698743 0.08 ENST00000524343.1
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr3_+_107318157 0.08 ENST00000406780.1
BBX
bobby sox homolog (Drosophila)
chr10_+_122610687 0.07 ENST00000263461.6
WDR11
WD repeat domain 11
chr1_+_158901329 0.07 ENST00000368140.1
ENST00000368138.3
ENST00000392254.2
ENST00000392252.3
ENST00000368135.4
PYHIN1
pyrin and HIN domain family, member 1
chr12_-_56693758 0.07 ENST00000547298.1
ENST00000551936.1
ENST00000551253.1
ENST00000551473.1
CS
citrate synthase
chr16_+_28303804 0.07 ENST00000341901.4
SBK1
SH3 domain binding kinase 1
chr14_+_50291993 0.07 ENST00000595378.1
AL627171.2
HCG1786899; PRO2610; Uncharacterized protein
chr1_+_223101757 0.07 ENST00000284476.6
DISP1
dispatched homolog 1 (Drosophila)
chr16_-_28303360 0.07 ENST00000501520.1
RP11-57A19.2
RP11-57A19.2
chr9_+_105757590 0.07 ENST00000374798.3
ENST00000487798.1
CYLC2
cylicin, basic protein of sperm head cytoskeleton 2
chr1_+_100598691 0.06 ENST00000370143.1
ENST00000370141.2
TRMT13
tRNA methyltransferase 13 homolog (S. cerevisiae)
chr19_-_38916822 0.06 ENST00000586305.1
RASGRP4
RAS guanyl releasing protein 4
chr2_+_179317994 0.06 ENST00000375129.4
DFNB59
deafness, autosomal recessive 59
chr10_-_12084770 0.05 ENST00000357604.5
UPF2
UPF2 regulator of nonsense transcripts homolog (yeast)
chr6_+_131894284 0.05 ENST00000368087.3
ENST00000356962.2
ARG1
arginase 1
chr1_+_156698708 0.05 ENST00000519086.1
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr10_-_61495760 0.05 ENST00000395347.1
SLC16A9
solute carrier family 16, member 9
chr5_-_176778803 0.04 ENST00000303127.7
LMAN2
lectin, mannose-binding 2
chr14_-_31856397 0.03 ENST00000538864.2
ENST00000550366.1
HEATR5A
HEAT repeat containing 5A
chr5_+_175511859 0.03 ENST00000503724.2
ENST00000253490.4
FAM153B
family with sequence similarity 153, member B
chr10_-_5046042 0.03 ENST00000421196.3
ENST00000455190.1
AKR1C2
aldo-keto reductase family 1, member C2
chr7_-_143966381 0.03 ENST00000487179.1
CTAGE8
CTAGE family, member 8
chr16_-_21442874 0.02 ENST00000534903.1
NPIPB3
nuclear pore complex interacting protein family, member B3
chr13_-_37633567 0.02 ENST00000464744.1
SUPT20H
suppressor of Ty 20 homolog (S. cerevisiae)
chr3_-_161089289 0.02 ENST00000497137.1
SPTSSB
serine palmitoyltransferase, small subunit B
chr8_+_77593448 0.02 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr7_-_33148975 0.02 ENST00000297157.3
RP9
retinitis pigmentosa 9 (autosomal dominant)
chr1_-_54303934 0.01 ENST00000537333.1
NDC1
NDC1 transmembrane nucleoporin
chr12_+_64173583 0.01 ENST00000261234.6
TMEM5
transmembrane protein 5
chr10_+_96162242 0.01 ENST00000225235.4
TBC1D12
TBC1 domain family, member 12
chr8_-_82359662 0.01 ENST00000519260.1
ENST00000256103.2
PMP2
peripheral myelin protein 2
chrX_+_69353284 0.01 ENST00000342206.6
ENST00000356413.4
IGBP1
immunoglobulin (CD79A) binding protein 1
chr2_-_88285309 0.01 ENST00000420840.2
RGPD2
RANBP2-like and GRIP domain containing 2
chr8_+_12803176 0.00 ENST00000524591.2
KIAA1456
KIAA1456
chr2_+_87144738 0.00 ENST00000559485.1
RGPD1
RANBP2-like and GRIP domain containing 1
chr9_-_37592561 0.00 ENST00000544379.1
ENST00000377773.5
ENST00000401811.3
ENST00000321301.6
TOMM5
translocase of outer mitochondrial membrane 5 homolog (yeast)
chr11_+_7618413 0.00 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.1 0.2 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685)
0.0 0.1 GO:0060345 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.0 0.1 GO:1900111 positive regulation of histone H3-K9 dimethylation(GO:1900111)
0.0 0.1 GO:0072616 interleukin-18 secretion(GO:0072616)
0.0 0.2 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.3 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.2 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.1 GO:0090467 L-arginine import(GO:0043091) arginine import(GO:0090467)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0097689 iron channel activity(GO:0097689)
0.0 0.1 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.0 0.1 GO:0004108 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.3 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)