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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SPI1

Z-value: 0.54

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Transcription factors associated with SPI1

Gene Symbol Gene ID Gene Info
SPI1
ENSG00000066336.7 Spi-1 proto-oncogene

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SPI1hg19_v2_chr11_-_47400062_474000770.295.7e-01Click!

Activity profile of SPI1 motif

Sorted Z-values of SPI1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_235098935 0.39 ENST00000423175.1
RP11-443B7.1
RP11-443B7.1
chr2_+_161993412 0.36 ENST00000259075.2
ENST00000432002.1
TANK
TRAF family member-associated NFKB activator
chr2_+_169658928 0.35 ENST00000317647.7
ENST00000445023.2
NOSTRIN
nitric oxide synthase trafficking
chr2_+_169659121 0.34 ENST00000397206.2
ENST00000397209.2
ENST00000421711.2
NOSTRIN
nitric oxide synthase trafficking
chr12_-_118796971 0.33 ENST00000542902.1
TAOK3
TAO kinase 3
chr1_-_114429997 0.33 ENST00000471267.1
ENST00000393320.3
BCL2L15
BCL2-like 15
chr2_+_228678550 0.28 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr1_-_197744763 0.28 ENST00000422998.1
DENND1B
DENN/MADD domain containing 1B
chr11_+_34642656 0.28 ENST00000257831.3
ENST00000450654.2
EHF
ets homologous factor
chr4_-_184580304 0.27 ENST00000510968.1
ENST00000512740.1
ENST00000327570.9
RWDD4
RWD domain containing 4
chr7_+_157129738 0.26 ENST00000437030.1
DNAJB6
DnaJ (Hsp40) homolog, subfamily B, member 6
chr1_-_101360331 0.26 ENST00000416479.1
ENST00000370113.3
EXTL2
exostosin-like glycosyltransferase 2
chr8_+_124194752 0.25 ENST00000318462.6
FAM83A
family with sequence similarity 83, member A
chr4_-_155533787 0.25 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
FGG
fibrinogen gamma chain
chr11_-_64764435 0.25 ENST00000534177.1
ENST00000301887.4
BATF2
basic leucine zipper transcription factor, ATF-like 2
chr10_+_94590910 0.25 ENST00000371547.4
EXOC6
exocyst complex component 6
chr2_+_161993465 0.25 ENST00000457476.1
TANK
TRAF family member-associated NFKB activator
chr1_+_205682497 0.24 ENST00000598338.1
AC119673.1
AC119673.1
chr17_+_38171681 0.24 ENST00000225474.2
ENST00000331769.2
ENST00000394148.3
ENST00000577675.1
CSF3
colony stimulating factor 3 (granulocyte)
chr9_-_115249484 0.22 ENST00000457681.1
C9orf147
chromosome 9 open reading frame 147
chr12_+_44152740 0.22 ENST00000440781.2
ENST00000431837.1
ENST00000550616.1
ENST00000448290.2
ENST00000551736.1
IRAK4
interleukin-1 receptor-associated kinase 4
chr15_-_64386120 0.22 ENST00000300030.3
FAM96A
family with sequence similarity 96, member A
chr2_+_231280954 0.22 ENST00000409824.1
ENST00000409341.1
ENST00000409112.1
ENST00000340126.4
ENST00000341950.4
SP100
SP100 nuclear antigen
chr5_-_39270725 0.21 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB
FYN binding protein
chr8_+_110551925 0.21 ENST00000395785.2
EBAG9
estrogen receptor binding site associated, antigen, 9
chr10_-_126849626 0.21 ENST00000530884.1
CTBP2
C-terminal binding protein 2
chr15_-_80263506 0.21 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr15_-_64385981 0.20 ENST00000557835.1
ENST00000380290.3
ENST00000559950.1
FAM96A
family with sequence similarity 96, member A
chr14_-_105071083 0.20 ENST00000415614.2
TMEM179
transmembrane protein 179
chr7_-_75241096 0.20 ENST00000420909.1
HIP1
huntingtin interacting protein 1
chr6_+_31895467 0.20 ENST00000556679.1
ENST00000456570.1
CFB
CFB
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr16_+_28914680 0.20 ENST00000564112.1
ATP2A1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr4_-_156298087 0.20 ENST00000311277.4
MAP9
microtubule-associated protein 9
chr14_-_35344093 0.20 ENST00000382422.2
BAZ1A
bromodomain adjacent to zinc finger domain, 1A
chr17_+_28443819 0.19 ENST00000479218.2
NSRP1
nuclear speckle splicing regulatory protein 1
chr16_-_30125177 0.19 ENST00000406256.3
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr6_+_31543334 0.19 ENST00000449264.2
TNF
tumor necrosis factor
chr11_-_85780853 0.19 ENST00000531930.1
ENST00000528398.1
PICALM
phosphatidylinositol binding clathrin assembly protein
chrX_-_131352152 0.19 ENST00000342983.2
RAP2C
RAP2C, member of RAS oncogene family
chr3_-_180397256 0.19 ENST00000442201.2
CCDC39
coiled-coil domain containing 39
chr10_-_32217717 0.19 ENST00000396144.4
ENST00000375245.4
ENST00000344936.2
ENST00000375250.5
ARHGAP12
Rho GTPase activating protein 12
chr4_-_156297949 0.19 ENST00000515654.1
MAP9
microtubule-associated protein 9
chr2_+_231280908 0.18 ENST00000427101.2
ENST00000432979.1
SP100
SP100 nuclear antigen
chr9_+_103204553 0.18 ENST00000502978.1
ENST00000334943.6
MSANTD3-TMEFF1
TMEFF1
MSANTD3-TMEFF1 readthrough
transmembrane protein with EGF-like and two follistatin-like domains 1
chr2_-_203103185 0.18 ENST00000409205.1
SUMO1
small ubiquitin-like modifier 1
chr4_-_54424366 0.18 ENST00000306888.2
LNX1
ligand of numb-protein X 1, E3 ubiquitin protein ligase
chr6_+_144980954 0.18 ENST00000367525.3
UTRN
utrophin
chr8_+_74903580 0.17 ENST00000284818.2
ENST00000518893.1
LY96
lymphocyte antigen 96
chr15_-_55489097 0.17 ENST00000260443.4
RSL24D1
ribosomal L24 domain containing 1
chr5_+_159895275 0.17 ENST00000517927.1
MIR146A
microRNA 146a
chr12_-_44200146 0.17 ENST00000395510.2
ENST00000325127.4
TWF1
twinfilin actin-binding protein 1
chr9_-_117568365 0.17 ENST00000374045.4
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chr6_+_139349903 0.17 ENST00000461027.1
ABRACL
ABRA C-terminal like
chr2_-_153574480 0.17 ENST00000410080.1
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr4_-_156297919 0.17 ENST00000450097.1
MAP9
microtubule-associated protein 9
chr4_-_184580353 0.17 ENST00000326397.5
RWDD4
RWD domain containing 4
chr15_-_55488817 0.17 ENST00000569386.1
RSL24D1
ribosomal L24 domain containing 1
chr4_+_184580420 0.17 ENST00000334690.6
ENST00000357207.4
TRAPPC11
trafficking protein particle complex 11
chr1_+_186798073 0.16 ENST00000367466.3
ENST00000442353.2
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr15_+_66161792 0.16 ENST00000564910.1
ENST00000261890.2
RAB11A
RAB11A, member RAS oncogene family
chr1_+_66796401 0.16 ENST00000528771.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr2_-_88355241 0.16 ENST00000347055.3
KRCC1
lysine-rich coiled-coil 1
chrX_-_48823165 0.16 ENST00000419374.1
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr21_-_27107198 0.16 ENST00000400094.1
ATP5J
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr8_+_121457642 0.16 ENST00000305949.1
MTBP
Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa
chr3_+_32726774 0.16 ENST00000538368.1
CNOT10
CCR4-NOT transcription complex, subunit 10
chr12_+_86268065 0.16 ENST00000551529.1
ENST00000256010.6
NTS
neurotensin
chr12_-_76461249 0.16 ENST00000551524.1
NAP1L1
nucleosome assembly protein 1-like 1
chr16_-_85969774 0.16 ENST00000598933.1
RP11-542M13.3
RP11-542M13.3
chr21_-_27107344 0.15 ENST00000457143.2
ATP5J
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr21_+_35107346 0.15 ENST00000456489.1
ITSN1
intersectin 1 (SH3 domain protein)
chr20_+_5731027 0.15 ENST00000378979.4
ENST00000303142.6
C20orf196
chromosome 20 open reading frame 196
chr17_+_62503147 0.15 ENST00000553412.1
CEP95
centrosomal protein 95kDa
chr1_-_150738261 0.15 ENST00000448301.2
ENST00000368985.3
CTSS
cathepsin S
chr14_-_24616426 0.15 ENST00000216802.5
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr3_-_72897545 0.15 ENST00000325599.8
SHQ1
SHQ1, H/ACA ribonucleoprotein assembly factor
chr15_-_33360342 0.15 ENST00000558197.1
FMN1
formin 1
chr16_+_53133070 0.15 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr2_+_37571845 0.15 ENST00000537448.1
QPCT
glutaminyl-peptide cyclotransferase
chr1_-_109618566 0.15 ENST00000338366.5
TAF13
TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
chr11_-_10822029 0.15 ENST00000528839.1
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr16_+_67063262 0.15 ENST00000565389.1
CBFB
core-binding factor, beta subunit
chr6_+_31895480 0.14 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
C2
CFB
complement component 2
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr4_-_77819002 0.14 ENST00000334306.2
SOWAHB
sosondowah ankyrin repeat domain family member B
chr16_-_67260901 0.14 ENST00000341546.3
ENST00000409509.1
ENST00000433915.1
ENST00000454102.2
LRRC29
AC040160.1
leucine rich repeat containing 29
Uncharacterized protein; cDNA FLJ57407, weakly similar to Mus musculus leucine rich repeat containing 29 (Lrrc29), mRNA
chr1_-_101360205 0.14 ENST00000450240.1
EXTL2
exostosin-like glycosyltransferase 2
chr5_-_58652788 0.14 ENST00000405755.2
PDE4D
phosphodiesterase 4D, cAMP-specific
chr7_-_37382360 0.14 ENST00000455119.1
ELMO1
engulfment and cell motility 1
chr1_-_110933663 0.14 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
SLC16A4
solute carrier family 16, member 4
chr8_-_28347737 0.14 ENST00000517673.1
ENST00000518734.1
ENST00000346498.2
ENST00000380254.2
FBXO16
F-box protein 16
chr7_+_77167376 0.14 ENST00000435495.2
PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr7_+_77167343 0.14 ENST00000433369.2
ENST00000415482.2
PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr12_+_52306113 0.14 ENST00000547400.1
ENST00000550683.1
ENST00000419526.2
ACVRL1
activin A receptor type II-like 1
chr2_-_148778323 0.14 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
ORC4
origin recognition complex, subunit 4
chr6_+_31553978 0.14 ENST00000376096.1
ENST00000376099.1
ENST00000376110.3
LST1
leukocyte specific transcript 1
chr5_-_171433548 0.14 ENST00000517395.1
FBXW11
F-box and WD repeat domain containing 11
chr1_+_209859510 0.14 ENST00000367028.2
ENST00000261465.1
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr14_-_35099377 0.14 ENST00000362031.4
SNX6
sorting nexin 6
chr6_-_155635583 0.13 ENST00000367166.4
TFB1M
transcription factor B1, mitochondrial
chr15_+_66161871 0.13 ENST00000569896.1
RAB11A
RAB11A, member RAS oncogene family
chr5_+_68530697 0.13 ENST00000256443.3
ENST00000514676.1
CDK7
cyclin-dependent kinase 7
chr12_-_44200052 0.13 ENST00000548315.1
ENST00000552521.1
ENST00000546662.1
ENST00000548403.1
ENST00000546506.1
TWF1
twinfilin actin-binding protein 1
chr3_-_167452262 0.13 ENST00000487947.2
PDCD10
programmed cell death 10
chrX_-_20284733 0.13 ENST00000438357.1
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr6_+_31554826 0.13 ENST00000376089.2
ENST00000396112.2
LST1
leukocyte specific transcript 1
chr15_+_66161802 0.13 ENST00000566233.1
ENST00000565075.1
ENST00000435304.2
RAB11A
RAB11A, member RAS oncogene family
chr15_-_59981479 0.13 ENST00000607373.1
BNIP2
BCL2/adenovirus E1B 19kDa interacting protein 2
chr1_-_110933611 0.13 ENST00000472422.2
ENST00000437429.2
SLC16A4
solute carrier family 16, member 4
chr2_+_177134201 0.13 ENST00000452865.1
MTX2
metaxin 2
chr3_+_113465866 0.13 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
ATP6V1A
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr4_-_156298028 0.13 ENST00000433024.1
ENST00000379248.2
MAP9
microtubule-associated protein 9
chr8_-_121457332 0.13 ENST00000518918.1
MRPL13
mitochondrial ribosomal protein L13
chr17_+_28443799 0.13 ENST00000584423.1
ENST00000247026.5
NSRP1
nuclear speckle splicing regulatory protein 1
chr7_+_86781778 0.13 ENST00000432937.2
DMTF1
cyclin D binding myb-like transcription factor 1
chr8_+_107630340 0.13 ENST00000497705.1
OXR1
oxidation resistance 1
chr17_+_32582293 0.13 ENST00000580907.1
ENST00000225831.4
CCL2
chemokine (C-C motif) ligand 2
chr14_+_23025534 0.13 ENST00000557595.1
AE000662.92
Uncharacterized protein
chr2_-_145275109 0.13 ENST00000431672.2
ZEB2
zinc finger E-box binding homeobox 2
chr15_+_77713222 0.13 ENST00000558176.1
HMG20A
high mobility group 20A
chr1_-_101360374 0.13 ENST00000535414.1
EXTL2
exostosin-like glycosyltransferase 2
chr5_+_35856951 0.13 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
IL7R
interleukin 7 receptor
chr1_-_235098861 0.12 ENST00000458044.1
RP11-443B7.1
RP11-443B7.1
chr6_-_108279369 0.12 ENST00000369002.4
SEC63
SEC63 homolog (S. cerevisiae)
chr8_+_82066514 0.12 ENST00000519412.1
ENST00000521953.1
RP11-1149M10.2
RP11-1149M10.2
chr1_+_66797687 0.12 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr11_+_102188224 0.12 ENST00000263464.3
BIRC3
baculoviral IAP repeat containing 3
chr11_+_76813886 0.12 ENST00000529803.1
OMP
olfactory marker protein
chr7_-_32338917 0.12 ENST00000396193.1
PDE1C
phosphodiesterase 1C, calmodulin-dependent 70kDa
chr17_+_28256874 0.12 ENST00000541045.1
ENST00000536908.2
EFCAB5
EF-hand calcium binding domain 5
chr1_+_172502336 0.12 ENST00000263688.3
SUCO
SUN domain containing ossification factor
chr1_-_159880159 0.12 ENST00000599780.1
AL590560.1
HCG1995379; Uncharacterized protein
chr2_+_158733088 0.12 ENST00000605860.1
UPP2
uridine phosphorylase 2
chr16_-_56485257 0.12 ENST00000300291.5
NUDT21
nudix (nucleoside diphosphate linked moiety X)-type motif 21
chr8_+_110552337 0.12 ENST00000337573.5
EBAG9
estrogen receptor binding site associated, antigen, 9
chr9_+_134001455 0.12 ENST00000531584.1
NUP214
nucleoporin 214kDa
chr5_-_87564620 0.12 ENST00000506536.1
ENST00000512429.1
ENST00000514135.1
ENST00000296595.6
ENST00000509387.1
TMEM161B
transmembrane protein 161B
chr15_+_63889577 0.12 ENST00000534939.1
ENST00000539570.3
FBXL22
F-box and leucine-rich repeat protein 22
chr11_+_102188272 0.12 ENST00000532808.1
BIRC3
baculoviral IAP repeat containing 3
chr11_+_111749650 0.12 ENST00000528125.1
C11orf1
chromosome 11 open reading frame 1
chr3_-_143567262 0.12 ENST00000474151.1
ENST00000316549.6
SLC9A9
solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
chr14_+_102276209 0.12 ENST00000445439.3
ENST00000334743.5
ENST00000557095.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr20_+_21283941 0.12 ENST00000377191.3
ENST00000430571.2
XRN2
5'-3' exoribonuclease 2
chr2_+_173955327 0.12 ENST00000422149.1
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr11_-_31832685 0.12 ENST00000438681.1
PAX6
paired box 6
chr3_-_120170052 0.12 ENST00000295633.3
FSTL1
follistatin-like 1
chr16_-_67597789 0.12 ENST00000605277.1
CTD-2012K14.6
CTD-2012K14.6
chr21_+_33671264 0.12 ENST00000339944.4
MRAP
melanocortin 2 receptor accessory protein
chr4_-_140005443 0.12 ENST00000510408.1
ENST00000420916.2
ENST00000358635.3
ELF2
E74-like factor 2 (ets domain transcription factor)
chr2_-_235405168 0.12 ENST00000339728.3
ARL4C
ADP-ribosylation factor-like 4C
chr17_+_62503073 0.12 ENST00000580188.1
ENST00000581056.1
CEP95
centrosomal protein 95kDa
chr17_+_38171614 0.12 ENST00000583218.1
ENST00000394149.3
CSF3
colony stimulating factor 3 (granulocyte)
chr21_-_27107283 0.12 ENST00000284971.3
ENST00000400099.1
ATP5J
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr17_-_62503015 0.12 ENST00000581806.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr8_-_101965559 0.12 ENST00000353245.3
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr3_-_149051194 0.12 ENST00000470080.1
TM4SF18
transmembrane 4 L six family member 18
chr5_-_180552304 0.12 ENST00000329365.2
OR2V1
olfactory receptor, family 2, subfamily V, member 1
chr8_+_86089619 0.12 ENST00000256117.5
ENST00000416274.2
E2F5
E2F transcription factor 5, p130-binding
chr3_-_167452703 0.11 ENST00000497056.2
ENST00000473645.2
PDCD10
programmed cell death 10
chr11_-_27528301 0.11 ENST00000524596.1
ENST00000278193.2
LIN7C
lin-7 homolog C (C. elegans)
chr3_+_136649311 0.11 ENST00000469404.1
ENST00000467911.1
NCK1
NCK adaptor protein 1
chr17_-_4710288 0.11 ENST00000571067.1
RP11-81A22.5
RP11-81A22.5
chr11_+_65407331 0.11 ENST00000527525.1
SIPA1
signal-induced proliferation-associated 1
chr7_-_127032363 0.11 ENST00000393312.1
ZNF800
zinc finger protein 800
chr14_-_35099315 0.11 ENST00000396526.3
ENST00000396534.3
ENST00000355110.5
ENST00000557265.1
SNX6
sorting nexin 6
chr4_-_140005341 0.11 ENST00000379549.2
ENST00000512627.1
ELF2
E74-like factor 2 (ets domain transcription factor)
chrX_-_134049233 0.11 ENST00000370779.4
MOSPD1
motile sperm domain containing 1
chr1_+_172502244 0.11 ENST00000610051.1
SUCO
SUN domain containing ossification factor
chr21_+_27107672 0.11 ENST00000400075.3
GABPA
GA binding protein transcription factor, alpha subunit 60kDa
chr7_+_99971129 0.11 ENST00000394000.2
ENST00000350573.2
PILRA
paired immunoglobin-like type 2 receptor alpha
chr2_-_153573887 0.11 ENST00000493468.2
ENST00000545856.1
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr4_+_95174445 0.11 ENST00000509418.1
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr2_-_10830093 0.11 ENST00000381685.5
ENST00000345985.3
ENST00000542668.1
ENST00000538384.1
NOL10
nucleolar protein 10
chrM_+_7586 0.11 ENST00000361739.1
MT-CO2
mitochondrially encoded cytochrome c oxidase II
chr8_+_124194875 0.11 ENST00000522648.1
ENST00000276699.6
FAM83A
family with sequence similarity 83, member A
chr11_+_6260298 0.11 ENST00000379936.2
CNGA4
cyclic nucleotide gated channel alpha 4
chr1_+_224301787 0.11 ENST00000366862.5
ENST00000424254.2
FBXO28
F-box protein 28
chr1_+_145439306 0.11 ENST00000425134.1
TXNIP
thioredoxin interacting protein
chr2_-_174828892 0.11 ENST00000418194.2
SP3
Sp3 transcription factor
chr17_+_47287749 0.11 ENST00000419580.2
ABI3
ABI family, member 3
chrX_-_118739835 0.11 ENST00000542113.1
ENST00000304449.5
NKRF
NFKB repressing factor
chr9_-_88969303 0.11 ENST00000277141.6
ENST00000375963.3
ZCCHC6
zinc finger, CCHC domain containing 6
chr9_+_2017063 0.11 ENST00000457226.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr9_-_88969339 0.11 ENST00000375960.2
ENST00000375961.2
ZCCHC6
zinc finger, CCHC domain containing 6
chr2_+_44502597 0.11 ENST00000260649.6
ENST00000409387.1
SLC3A1
solute carrier family 3 (amino acid transporter heavy chain), member 1
chr2_-_203103281 0.11 ENST00000392244.3
ENST00000409181.1
ENST00000409712.1
ENST00000409498.2
ENST00000409368.1
ENST00000392245.1
ENST00000392246.2
SUMO1
small ubiquitin-like modifier 1
chr7_+_86781677 0.11 ENST00000331242.7
ENST00000394702.3
ENST00000413276.2
ENST00000446796.2
ENST00000411766.2
ENST00000420131.1
ENST00000414630.2
ENST00000453049.1
ENST00000428819.1
ENST00000448598.1
ENST00000449088.3
ENST00000430405.3
DMTF1
cyclin D binding myb-like transcription factor 1
chr10_+_64893039 0.10 ENST00000277746.6
ENST00000435510.2
NRBF2
nuclear receptor binding factor 2
chr19_+_50003781 0.10 ENST00000602157.1
hsa-mir-150
hsa-mir-150
chr6_+_142468383 0.10 ENST00000367621.1
ENST00000452973.2
VTA1
vesicle (multivesicular body) trafficking 1
chr18_+_61445007 0.10 ENST00000447428.1
ENST00000546027.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr2_+_29117509 0.10 ENST00000407426.3
WDR43
WD repeat domain 43
chr6_-_6007200 0.10 ENST00000244766.2
NRN1
neuritin 1
chr3_-_167452614 0.10 ENST00000392750.2
ENST00000464360.1
ENST00000492139.1
ENST00000471885.1
ENST00000470131.1
PDCD10
programmed cell death 10
chr2_+_121010413 0.10 ENST00000404963.3
RALB
v-ral simian leukemia viral oncogene homolog B
chr2_+_152214098 0.10 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chrX_-_47489244 0.10 ENST00000469388.1
ENST00000396992.3
ENST00000377005.2
CFP
complement factor properdin
chr10_+_76970762 0.10 ENST00000447677.1
VDAC2
voltage-dependent anion channel 2
chr12_+_21679220 0.10 ENST00000256969.2
C12orf39
chromosome 12 open reading frame 39
chr3_-_149051444 0.10 ENST00000296059.2
TM4SF18
transmembrane 4 L six family member 18
chr14_-_50999307 0.10 ENST00000013125.4
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5

Network of associatons between targets according to the STRING database.

First level regulatory network of SPI1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.1 0.3 GO:0042222 interleukin-1 biosynthetic process(GO:0042222) regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.1 0.2 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.1 0.6 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.4 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 0.3 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 0.2 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.1 0.4 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.1 0.2 GO:1904833 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) positive regulation of translational initiation by iron(GO:0045994) positive regulation of superoxide dismutase activity(GO:1901671) positive regulation of removal of superoxide radicals(GO:1904833)
0.1 0.7 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.1 0.2 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.4 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.0 0.2 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.5 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0031446 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.0 0.2 GO:0044027 DNA hypermethylation(GO:0044026) hypermethylation of CpG island(GO:0044027)
0.0 0.4 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.0 0.0 GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.0 0.2 GO:0001928 regulation of exocyst assembly(GO:0001928) regulation of exocyst localization(GO:0060178)
0.0 0.1 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.0 0.1 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.0 0.4 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.0 0.0 GO:0032460 negative regulation of protein oligomerization(GO:0032460)
0.0 0.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.1 GO:0070668 regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.0 0.2 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.1 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.2 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.1 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.5 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.2 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.4 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.2 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.2 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.2 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.1 GO:0097694 establishment of RNA localization to telomere(GO:0097694) establishment of macromolecular complex localization to telomere(GO:0097695)
0.0 0.2 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.1 GO:0035983 response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.0 0.2 GO:0072425 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.2 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.1 GO:0046108 uridine metabolic process(GO:0046108)
0.0 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.1 GO:0002349 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 0.1 GO:1900244 synaptic vesicle recycling via endosome(GO:0036466) positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle recycling(GO:1903423) positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076) positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.2 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.3 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.2 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.0 0.1 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.0 GO:0032097 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0 0.1 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0 0.2 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.1 GO:0090070 regulation of ribosome biogenesis(GO:0090069) positive regulation of ribosome biogenesis(GO:0090070) regulation of rRNA processing(GO:2000232) positive regulation of rRNA processing(GO:2000234)
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.0 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.1 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.1 GO:0023035 CD40 signaling pathway(GO:0023035)
0.0 0.0 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0 0.1 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.0 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.1 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.1 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.0 0.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.1 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.1 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.0 0.1 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.1 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.0 GO:0042704 detection of oxygen(GO:0003032) uterine wall breakdown(GO:0042704)
0.0 0.2 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.0 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.0 0.0 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.1 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.2 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.0 GO:2000437 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.0 0.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.0 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.3 GO:2000587 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 0.0 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.2 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.0 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.2 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.2 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.3 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.0 0.0 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.1 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.0 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.0 0.0 GO:1902304 phosphatidylserine exposure on blood platelet(GO:0097045) positive regulation of potassium ion export(GO:1902304)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0035811 negative regulation of urine volume(GO:0035811)
0.0 0.0 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:0021603 cranial nerve formation(GO:0021603)
0.0 0.0 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.0 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0 0.3 GO:0010544 negative regulation of platelet activation(GO:0010544)
0.0 0.3 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.1 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.1 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.0 0.8 GO:0050999 regulation of nitric-oxide synthase activity(GO:0050999)
0.0 0.0 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 0.2 GO:0008623 CHRAC(GO:0008623)
0.1 0.3 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.1 0.2 GO:0070985 TFIIK complex(GO:0070985)
0.0 0.3 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.2 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.6 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.2 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.4 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.2 GO:0097422 tubular endosome(GO:0097422)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.1 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.1 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.1 GO:0005849 mRNA cleavage factor complex(GO:0005849)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.1 0.3 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.1 0.2 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.1 0.6 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.2 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 0.1 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.2 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 0.3 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.3 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.1 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.0 0.1 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.0 0.3 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.2 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.1 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.2 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.2 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.2 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.0 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.8 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 0.0 GO:0005365 myo-inositol transmembrane transporter activity(GO:0005365)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.0 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.0 GO:0019961 interferon binding(GO:0019961)
0.0 0.4 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 0.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.0 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.0 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.2 GO:0071837 HMG box domain binding(GO:0071837)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.4 ST G ALPHA S PATHWAY G alpha s Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.0 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.3 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.4 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.7 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.0 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage