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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SPIB

Z-value: 0.91

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Transcription factors associated with SPIB

Gene Symbol Gene ID Gene Info
SPIB
ENSG00000269404.2 Spi-B transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SPIBhg19_v2_chr19_+_50922187_509222150.404.3e-01Click!

Activity profile of SPIB motif

Sorted Z-values of SPIB motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_112016414 0.76 ENST00000343534.5
ENST00000369718.3
C1orf162
chromosome 1 open reading frame 162
chrX_-_47489244 0.72 ENST00000469388.1
ENST00000396992.3
ENST00000377005.2
CFP
complement factor properdin
chr15_-_33360342 0.59 ENST00000558197.1
FMN1
formin 1
chr19_+_42381337 0.42 ENST00000597454.1
ENST00000444740.2
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr9_+_2017063 0.38 ENST00000457226.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr3_-_180397256 0.38 ENST00000442201.2
CCDC39
coiled-coil domain containing 39
chr8_+_121457642 0.36 ENST00000305949.1
MTBP
Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa
chr8_+_74903580 0.36 ENST00000284818.2
ENST00000518893.1
LY96
lymphocyte antigen 96
chr2_-_43019698 0.32 ENST00000431905.1
ENST00000294973.6
HAAO
3-hydroxyanthranilate 3,4-dioxygenase
chr12_-_15114492 0.32 ENST00000541546.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr6_+_26251835 0.31 ENST00000356350.2
HIST1H2BH
histone cluster 1, H2bh
chr8_+_125860939 0.30 ENST00000525292.1
ENST00000528090.1
LINC00964
long intergenic non-protein coding RNA 964
chr6_-_56708459 0.30 ENST00000370788.2
DST
dystonin
chr8_-_25281747 0.30 ENST00000421054.2
GNRH1
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr16_-_4850471 0.30 ENST00000592019.1
ENST00000586153.1
ROGDI
rogdi homolog (Drosophila)
chr22_-_37880543 0.29 ENST00000442496.1
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr1_+_120839412 0.29 ENST00000355228.4
FAM72B
family with sequence similarity 72, member B
chr15_+_91427691 0.29 ENST00000559355.1
ENST00000394302.1
FES
feline sarcoma oncogene
chr2_+_138722028 0.29 ENST00000280096.5
HNMT
histamine N-methyltransferase
chr19_+_35940486 0.28 ENST00000246549.2
FFAR2
free fatty acid receptor 2
chr3_-_176914191 0.28 ENST00000437738.1
ENST00000424913.1
ENST00000443315.1
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chrX_+_24167828 0.27 ENST00000379188.3
ENST00000419690.1
ENST00000379177.1
ENST00000304543.5
ZFX
zinc finger protein, X-linked
chr15_+_91427642 0.27 ENST00000328850.3
ENST00000414248.2
FES
feline sarcoma oncogene
chr1_+_173991633 0.26 ENST00000424181.1
RP11-160H22.3
RP11-160H22.3
chr1_+_209941827 0.26 ENST00000367023.1
TRAF3IP3
TRAF3 interacting protein 3
chr11_-_1606513 0.26 ENST00000382171.2
KRTAP5-1
keratin associated protein 5-1
chr20_+_20033158 0.26 ENST00000340348.6
ENST00000377309.2
ENST00000389656.3
ENST00000377306.1
ENST00000245957.5
ENST00000377303.2
ENST00000475466.1
C20orf26
chromosome 20 open reading frame 26
chr6_-_56707943 0.26 ENST00000370769.4
ENST00000421834.2
ENST00000312431.6
ENST00000361203.3
ENST00000523817.1
DST
dystonin
chr9_-_95640218 0.26 ENST00000395506.3
ENST00000375495.3
ENST00000332591.6
ZNF484
zinc finger protein 484
chr15_-_65809581 0.25 ENST00000341861.5
DPP8
dipeptidyl-peptidase 8
chr3_+_184530173 0.25 ENST00000453056.1
VPS8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr1_-_45956868 0.24 ENST00000451835.2
TESK2
testis-specific kinase 2
chr17_+_32597232 0.24 ENST00000378569.2
ENST00000200307.4
ENST00000394627.1
ENST00000394630.3
CCL7
chemokine (C-C motif) ligand 7
chr8_+_27632083 0.24 ENST00000519637.1
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr5_-_158757895 0.23 ENST00000231228.2
IL12B
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
chr15_-_33360085 0.23 ENST00000334528.9
FMN1
formin 1
chr17_-_27467418 0.23 ENST00000528564.1
MYO18A
myosin XVIIIA
chr3_+_16926441 0.23 ENST00000418129.2
ENST00000396755.2
PLCL2
phospholipase C-like 2
chr11_-_64512273 0.23 ENST00000377497.3
ENST00000377487.1
ENST00000430645.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr2_+_196440692 0.23 ENST00000458054.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr8_+_125985531 0.22 ENST00000319286.5
ZNF572
zinc finger protein 572
chr19_+_35939154 0.21 ENST00000599180.2
FFAR2
free fatty acid receptor 2
chrX_+_123094672 0.21 ENST00000354548.5
ENST00000458700.1
STAG2
stromal antigen 2
chr5_-_10249990 0.21 ENST00000511437.1
ENST00000280330.8
ENST00000510047.1
FAM173B
family with sequence similarity 173, member B
chrX_+_123094369 0.21 ENST00000455404.1
ENST00000218089.9
STAG2
stromal antigen 2
chr21_-_32716556 0.20 ENST00000455508.1
TIAM1
T-cell lymphoma invasion and metastasis 1
chr15_-_65809625 0.20 ENST00000560436.1
DPP8
dipeptidyl-peptidase 8
chr8_-_74206133 0.20 ENST00000352983.2
RPL7
ribosomal protein L7
chr3_-_143567262 0.20 ENST00000474151.1
ENST00000316549.6
SLC9A9
solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
chr2_-_188419200 0.20 ENST00000233156.3
ENST00000426055.1
ENST00000453013.1
ENST00000417013.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr2_+_102758210 0.20 ENST00000450319.1
IL1R1
interleukin 1 receptor, type I
chr17_+_65374075 0.19 ENST00000581322.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr7_+_23637118 0.19 ENST00000448353.1
CCDC126
coiled-coil domain containing 126
chr7_-_150038704 0.19 ENST00000466675.1
ENST00000482669.1
ENST00000467793.1
ENST00000223271.3
RARRES2
retinoic acid receptor responder (tazarotene induced) 2
chr12_-_53901266 0.19 ENST00000609999.1
ENST00000267017.3
NPFF
neuropeptide FF-amide peptide precursor
chr8_-_121457332 0.19 ENST00000518918.1
MRPL13
mitochondrial ribosomal protein L13
chr4_-_146859787 0.19 ENST00000508784.1
ZNF827
zinc finger protein 827
chr9_-_14693417 0.18 ENST00000380916.4
ZDHHC21
zinc finger, DHHC-type containing 21
chr1_-_222886526 0.18 ENST00000541237.1
AIDA
axin interactor, dorsalization associated
chr3_-_114035026 0.18 ENST00000570269.1
RP11-553L6.5
RP11-553L6.5
chrX_+_24167746 0.18 ENST00000428571.1
ENST00000539115.1
ZFX
zinc finger protein, X-linked
chr14_+_102228123 0.18 ENST00000422945.2
ENST00000554442.1
ENST00000556260.2
ENST00000328724.5
ENST00000557268.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr2_-_64751227 0.18 ENST00000561559.1
RP11-568N6.1
RP11-568N6.1
chr8_-_121457608 0.18 ENST00000306185.3
MRPL13
mitochondrial ribosomal protein L13
chr19_+_10959043 0.17 ENST00000397820.4
C19orf38
chromosome 19 open reading frame 38
chr14_+_96968802 0.17 ENST00000556619.1
ENST00000392990.2
PAPOLA
poly(A) polymerase alpha
chr5_+_102455968 0.17 ENST00000358359.3
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr12_+_50355647 0.17 ENST00000293599.6
AQP5
aquaporin 5
chr1_+_90287480 0.17 ENST00000394593.3
LRRC8D
leucine rich repeat containing 8 family, member D
chr22_+_17082732 0.17 ENST00000558085.2
ENST00000592918.1
ENST00000400593.2
ENST00000592107.1
ENST00000426585.1
ENST00000591299.1
TPTEP1
transmembrane phosphatase with tensin homology pseudogene 1
chr13_-_95364389 0.17 ENST00000376945.2
SOX21
SRY (sex determining region Y)-box 21
chr14_+_96968707 0.17 ENST00000216277.8
ENST00000557320.1
ENST00000557471.1
PAPOLA
poly(A) polymerase alpha
chr4_-_47916543 0.17 ENST00000507489.1
NFXL1
nuclear transcription factor, X-box binding-like 1
chr3_+_23847394 0.16 ENST00000306627.3
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chr20_-_20033052 0.16 ENST00000536226.1
CRNKL1
crooked neck pre-mRNA splicing factor 1
chr1_-_179851611 0.16 ENST00000610272.1
RP11-533E19.7
RP11-533E19.7
chr4_+_190861941 0.16 ENST00000226798.4
FRG1
FSHD region gene 1
chr6_+_31553978 0.16 ENST00000376096.1
ENST00000376099.1
ENST00000376110.3
LST1
leukocyte specific transcript 1
chr8_-_74205851 0.16 ENST00000396467.1
RPL7
ribosomal protein L7
chr8_-_6420759 0.16 ENST00000523120.1
ANGPT2
angiopoietin 2
chr2_-_74405929 0.16 ENST00000396049.4
MOB1A
MOB kinase activator 1A
chr10_-_14596140 0.15 ENST00000496330.1
FAM107B
family with sequence similarity 107, member B
chr2_-_188419078 0.15 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr3_+_23847432 0.15 ENST00000346855.3
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chr10_+_114135952 0.15 ENST00000356116.1
ENST00000433418.1
ENST00000354273.4
ACSL5
acyl-CoA synthetase long-chain family member 5
chr9_+_104296163 0.15 ENST00000374819.2
ENST00000479306.1
RNF20
ring finger protein 20, E3 ubiquitin protein ligase
chr15_-_83224682 0.15 ENST00000562833.1
RP11-152F13.10
RP11-152F13.10
chr6_+_31554826 0.15 ENST00000376089.2
ENST00000396112.2
LST1
leukocyte specific transcript 1
chr12_-_15114603 0.15 ENST00000228945.4
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr1_+_167298281 0.15 ENST00000367862.5
POU2F1
POU class 2 homeobox 1
chr17_-_29641104 0.15 ENST00000577894.1
ENST00000330927.4
EVI2B
ecotropic viral integration site 2B
chr11_-_8680383 0.15 ENST00000299550.6
TRIM66
tripartite motif containing 66
chr15_+_86098670 0.15 ENST00000558811.1
AKAP13
A kinase (PRKA) anchor protein 13
chr4_+_190861993 0.15 ENST00000524583.1
ENST00000531991.2
FRG1
FSHD region gene 1
chr1_+_104068312 0.15 ENST00000524631.1
ENST00000531883.1
ENST00000533099.1
ENST00000527062.1
RNPC3
RNA-binding region (RNP1, RRM) containing 3
chr4_-_140005341 0.14 ENST00000379549.2
ENST00000512627.1
ELF2
E74-like factor 2 (ets domain transcription factor)
chr4_-_47916613 0.14 ENST00000381538.3
ENST00000329043.3
NFXL1
nuclear transcription factor, X-box binding-like 1
chr14_+_32546145 0.14 ENST00000556611.1
ENST00000539826.2
ARHGAP5
Rho GTPase activating protein 5
chr14_+_74417192 0.14 ENST00000554320.1
COQ6
coenzyme Q6 monooxygenase
chr1_+_66796401 0.14 ENST00000528771.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr19_+_49838653 0.14 ENST00000598095.1
ENST00000426897.2
ENST00000323906.4
ENST00000535669.2
ENST00000597602.1
ENST00000595660.1
CD37
CD37 molecule
chr5_-_64858944 0.14 ENST00000508421.1
ENST00000510693.1
ENST00000514814.1
ENST00000515497.1
ENST00000396679.1
CENPK
centromere protein K
chr5_-_58335281 0.14 ENST00000358923.6
PDE4D
phosphodiesterase 4D, cAMP-specific
chr8_-_95449155 0.14 ENST00000481490.2
FSBP
fibrinogen silencer binding protein
chr1_-_45956822 0.14 ENST00000372086.3
ENST00000341771.6
TESK2
testis-specific kinase 2
chr7_+_86781778 0.14 ENST00000432937.2
DMTF1
cyclin D binding myb-like transcription factor 1
chr3_-_16554881 0.14 ENST00000451036.1
RFTN1
raftlin, lipid raft linker 1
chr10_-_74856608 0.14 ENST00000307116.2
ENST00000373008.2
ENST00000412021.2
ENST00000394890.2
ENST00000263556.3
ENST00000440381.1
P4HA1
prolyl 4-hydroxylase, alpha polypeptide I
chr19_-_48867171 0.14 ENST00000377431.2
ENST00000436660.2
ENST00000541566.1
TMEM143
transmembrane protein 143
chr13_+_108922228 0.13 ENST00000542136.1
TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr14_-_80678512 0.13 ENST00000553968.1
DIO2
deiodinase, iodothyronine, type II
chr7_-_37488777 0.13 ENST00000445322.1
ENST00000448602.1
ELMO1
engulfment and cell motility 1
chr16_+_31213206 0.13 ENST00000561916.2
C16orf98
chromosome 16 open reading frame 98
chr15_+_91427726 0.13 ENST00000452243.1
FES
feline sarcoma oncogene
chr10_-_65028817 0.13 ENST00000542921.1
JMJD1C
jumonji domain containing 1C
chr4_-_10686475 0.13 ENST00000226951.6
CLNK
cytokine-dependent hematopoietic cell linker
chr2_+_64751433 0.13 ENST00000238856.4
ENST00000422803.1
ENST00000238855.7
AFTPH
aftiphilin
chr3_+_239652 0.13 ENST00000435603.1
CHL1
cell adhesion molecule L1-like
chr14_-_67826486 0.13 ENST00000555431.1
ENST00000554236.1
ENST00000555474.1
ATP6V1D
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
chr15_-_65810042 0.13 ENST00000321147.6
DPP8
dipeptidyl-peptidase 8
chr1_+_222886694 0.13 ENST00000426638.1
ENST00000537020.1
ENST00000539697.1
BROX
BRO1 domain and CAAX motif containing
chr4_-_103266626 0.12 ENST00000356736.4
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr5_+_118668846 0.12 ENST00000513374.1
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr3_+_4535155 0.12 ENST00000544951.1
ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
chr20_+_5931275 0.12 ENST00000378896.3
ENST00000378883.1
MCM8
minichromosome maintenance complex component 8
chr14_+_45431379 0.12 ENST00000361577.3
ENST00000361462.2
ENST00000382233.2
FAM179B
family with sequence similarity 179, member B
chr1_+_205473720 0.12 ENST00000429964.2
ENST00000506784.1
ENST00000360066.2
CDK18
cyclin-dependent kinase 18
chr20_+_5931497 0.12 ENST00000378886.2
ENST00000265187.4
MCM8
minichromosome maintenance complex component 8
chr7_-_37382360 0.12 ENST00000455119.1
ELMO1
engulfment and cell motility 1
chr11_-_47400032 0.12 ENST00000533968.1
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr6_-_49430886 0.12 ENST00000274813.3
MUT
methylmalonyl CoA mutase
chr5_+_64859066 0.12 ENST00000261308.5
ENST00000535264.1
ENST00000538977.1
PPWD1
peptidylprolyl isomerase domain and WD repeat containing 1
chr8_-_125551278 0.12 ENST00000519232.1
ENST00000523888.1
ENST00000522810.1
ENST00000519548.1
ENST00000517678.1
ENST00000605953.1
ENST00000276692.6
TATDN1
TatD DNase domain containing 1
chr6_+_142468383 0.12 ENST00000367621.1
ENST00000452973.2
VTA1
vesicle (multivesicular body) trafficking 1
chr5_-_66492562 0.12 ENST00000256447.4
CD180
CD180 molecule
chr17_+_28443799 0.12 ENST00000584423.1
ENST00000247026.5
NSRP1
nuclear speckle splicing regulatory protein 1
chr12_-_122240792 0.12 ENST00000545885.1
ENST00000542933.1
ENST00000428029.2
ENST00000541694.1
ENST00000536662.1
ENST00000535643.1
ENST00000541657.1
AC084018.1
RHOF
AC084018.1
ras homolog family member F (in filopodia)
chr15_-_66084621 0.11 ENST00000564674.1
DENND4A
DENN/MADD domain containing 4A
chr20_-_5931051 0.11 ENST00000453074.2
TRMT6
tRNA methyltransferase 6 homolog (S. cerevisiae)
chr7_-_19157248 0.11 ENST00000242261.5
TWIST1
twist family bHLH transcription factor 1
chr1_-_54879140 0.11 ENST00000525990.1
SSBP3
single stranded DNA binding protein 3
chr13_+_36050881 0.11 ENST00000537702.1
NBEA
neurobeachin
chr1_-_43282906 0.11 ENST00000372521.4
CCDC23
coiled-coil domain containing 23
chr17_+_7461781 0.11 ENST00000349228.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr9_-_34397800 0.11 ENST00000297623.2
C9orf24
chromosome 9 open reading frame 24
chr11_-_10920838 0.11 ENST00000503469.2
CTD-2003C8.2
CTD-2003C8.2
chr17_-_72619869 0.11 ENST00000392619.1
ENST00000426295.2
CD300E
CD300e molecule
chr1_-_17380630 0.11 ENST00000375499.3
SDHB
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr17_+_7462031 0.11 ENST00000380535.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr5_-_140013241 0.11 ENST00000519715.1
CD14
CD14 molecule
chr10_+_7830125 0.11 ENST00000335698.4
ENST00000541227.1
ATP5C1
ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
chr2_+_102758271 0.11 ENST00000428279.1
IL1R1
interleukin 1 receptor, type I
chr11_-_64512803 0.11 ENST00000377489.1
ENST00000354024.3
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr6_-_139308777 0.11 ENST00000529597.1
ENST00000415951.2
ENST00000367663.4
ENST00000409812.2
REPS1
RALBP1 associated Eps domain containing 1
chr6_+_49431073 0.11 ENST00000335783.3
CENPQ
centromere protein Q
chr5_-_39270725 0.11 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB
FYN binding protein
chr2_-_180871780 0.11 ENST00000410053.3
ENST00000295749.6
ENST00000404136.2
CWC22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr1_+_151129103 0.11 ENST00000368910.3
TNFAIP8L2
tumor necrosis factor, alpha-induced protein 8-like 2
chr5_-_140013224 0.10 ENST00000498971.2
CD14
CD14 molecule
chr17_+_7461613 0.10 ENST00000438470.1
ENST00000436057.1
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr6_-_110012380 0.10 ENST00000424296.2
ENST00000341338.6
ENST00000368948.2
ENST00000285397.5
AK9
adenylate kinase 9
chr9_+_215158 0.10 ENST00000479404.1
DOCK8
dedicator of cytokinesis 8
chr12_+_32638897 0.10 ENST00000531134.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr7_+_23636992 0.10 ENST00000307471.3
ENST00000409765.1
CCDC126
coiled-coil domain containing 126
chr19_-_15344243 0.10 ENST00000602233.1
EPHX3
epoxide hydrolase 3
chr6_+_22221010 0.10 ENST00000567753.1
RP11-524C21.2
RP11-524C21.2
chr17_-_4642429 0.10 ENST00000573123.1
CXCL16
chemokine (C-X-C motif) ligand 16
chr11_-_64570624 0.10 ENST00000439069.1
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
chr6_-_47009996 0.10 ENST00000371243.2
GPR110
G protein-coupled receptor 110
chr3_-_155462808 0.10 ENST00000460012.1
PLCH1
phospholipase C, eta 1
chr9_+_104296243 0.10 ENST00000466817.1
RNF20
ring finger protein 20, E3 ubiquitin protein ligase
chr8_-_131028869 0.10 ENST00000518283.1
ENST00000519110.1
FAM49B
family with sequence similarity 49, member B
chr22_+_20905269 0.10 ENST00000457322.1
MED15
mediator complex subunit 15
chr10_-_7829909 0.10 ENST00000379562.4
ENST00000543003.1
ENST00000535925.1
KIN
KIN, antigenic determinant of recA protein homolog (mouse)
chr3_-_178984759 0.10 ENST00000349697.2
ENST00000497599.1
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr14_+_102276209 0.10 ENST00000445439.3
ENST00000334743.5
ENST00000557095.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr3_-_176914238 0.10 ENST00000430069.1
ENST00000428970.1
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr1_-_175161890 0.10 ENST00000545251.2
ENST00000423313.1
KIAA0040
KIAA0040
chr18_-_32924372 0.10 ENST00000261332.6
ENST00000399061.3
ZNF24
zinc finger protein 24
chr2_-_174830430 0.10 ENST00000310015.6
ENST00000455789.2
SP3
Sp3 transcription factor
chr7_-_135662056 0.10 ENST00000393085.3
ENST00000435723.1
MTPN
myotrophin
chr12_-_110939870 0.10 ENST00000447578.2
ENST00000546588.1
ENST00000360579.7
ENST00000549970.1
ENST00000549578.1
VPS29
vacuolar protein sorting 29 homolog (S. cerevisiae)
chr10_+_7830092 0.09 ENST00000356708.7
ATP5C1
ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
chr1_-_31230650 0.09 ENST00000294507.3
LAPTM5
lysosomal protein transmembrane 5
chr3_+_184529948 0.09 ENST00000436792.2
ENST00000446204.2
ENST00000422105.1
VPS8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chrX_+_11777671 0.09 ENST00000380693.3
ENST00000380692.2
MSL3
male-specific lethal 3 homolog (Drosophila)
chr8_-_77912431 0.09 ENST00000357039.4
ENST00000522527.1
PEX2
peroxisomal biogenesis factor 2
chr19_+_51728316 0.09 ENST00000436584.2
ENST00000421133.2
ENST00000391796.3
ENST00000262262.4
CD33
CD33 molecule
chr8_+_104426942 0.09 ENST00000297579.5
DCAF13
DDB1 and CUL4 associated factor 13
chr14_+_102276132 0.09 ENST00000350249.3
ENST00000557621.1
ENST00000556946.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr1_+_161551101 0.09 ENST00000367962.4
ENST00000367960.5
ENST00000403078.3
ENST00000428605.2
FCGR2B
Fc fragment of IgG, low affinity IIb, receptor (CD32)
chr15_+_50716576 0.09 ENST00000560297.1
ENST00000307179.4
ENST00000396444.3
ENST00000433963.1
ENST00000425032.3
USP8
ubiquitin specific peptidase 8
chr15_+_77287715 0.09 ENST00000559161.1
PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chr3_+_184529929 0.09 ENST00000287546.4
ENST00000437079.3
VPS8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr7_+_139529085 0.09 ENST00000539806.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr19_-_3479086 0.09 ENST00000587847.1
C19orf77
chromosome 19 open reading frame 77
chrX_+_24072833 0.09 ENST00000253039.4
EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr3_-_179169330 0.09 ENST00000232564.3
GNB4
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr8_+_27632047 0.09 ENST00000397418.2
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr16_-_19725899 0.09 ENST00000567367.1
KNOP1
lysine-rich nucleolar protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of SPIB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232)
0.1 0.8 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 0.3 GO:1990637 response to prolactin(GO:1990637) regulation of ovarian follicle development(GO:2000354)
0.1 0.7 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 0.5 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.3 GO:0044026 DNA hypermethylation(GO:0044026) hypermethylation of CpG island(GO:0044027)
0.1 0.3 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 0.2 GO:0019732 antifungal humoral response(GO:0019732)
0.1 0.3 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.4 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.1 0.2 GO:0061570 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.1 0.1 GO:0002605 negative regulation of dendritic cell antigen processing and presentation(GO:0002605)
0.1 0.2 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 0.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.3 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.0 0.3 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.2 GO:0070253 somatostatin secretion(GO:0070253)
0.0 0.2 GO:2000330 positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.0 0.3 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.2 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.0 0.3 GO:0071727 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.0 0.4 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.2 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.2 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.1 GO:2000276 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 0.1 GO:0097065 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.0 0.6 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.2 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.3 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.8 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.0 0.2 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.0 0.4 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.2 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0 0.4 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0002636 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.0 0.1 GO:0061485 memory T cell proliferation(GO:0061485)
0.0 0.4 GO:0060613 fat pad development(GO:0060613)
0.0 0.1 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.1 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.3 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.0 GO:0090427 activation of meiosis(GO:0090427)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0043375 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.0 0.3 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.5 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.0 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.1 GO:0052056 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.1 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.1 GO:0071226 response to molecule of fungal origin(GO:0002238) cellular response to molecule of fungal origin(GO:0071226)
0.0 0.1 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0 0.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.0 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.0 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.0 0.1 GO:1904879 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.0 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.2 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.0 0.2 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.0 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.0 0.1 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0031673 H zone(GO:0031673)
0.1 0.5 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.2 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.4 GO:0033263 CORVET complex(GO:0033263)
0.0 0.2 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.3 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.3 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.3 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.3 GO:0033503 HULC complex(GO:0033503)
0.0 0.1 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.3 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0031906 late endosome lumen(GO:0031906)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.3 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 0.3 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.1 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.2 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.0 0.3 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.3 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.2 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.1 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.1 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.2 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.6 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling