Project

A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

Navigation
Downloads

Results for STAT1_STAT3_BCL6

Z-value: 0.97

Motif logo

Transcription factors associated with STAT1_STAT3_BCL6

Gene Symbol Gene ID Gene Info
ENSG00000115415.14 signal transducer and activator of transcription 1
ENSG00000168610.10 signal transducer and activator of transcription 3
ENSG00000113916.13 BCL6 transcription repressor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BCL6hg19_v2_chr3_-_187455680_187455732-0.532.8e-01Click!
STAT3hg19_v2_chr17_-_40540586_40540600-0.335.2e-01Click!
STAT1hg19_v2_chr2_-_191878874_1918789760.157.8e-01Click!

Activity profile of STAT1_STAT3_BCL6 motif

Sorted Z-values of STAT1_STAT3_BCL6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_50649192 1.94 ENST00000443053.2
ENST00000348721.3
cytokine inducible SH2-containing protein
chr17_-_46692457 1.81 ENST00000468443.1
homeobox B8
chr19_-_4717835 0.97 ENST00000599248.1
dipeptidyl-peptidase 9
chr3_-_52864680 0.76 ENST00000406595.1
ENST00000485816.1
ENST00000434759.3
ENST00000346281.5
ENST00000266041.4
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr16_-_67517716 0.68 ENST00000290953.2
agouti related protein homolog (mouse)
chr6_+_26104104 0.67 ENST00000377803.2
histone cluster 1, H4c
chr2_+_9778872 0.65 ENST00000478468.1
RP11-521D12.1
chr17_+_2264983 0.62 ENST00000574650.1
small G protein signaling modulator 2
chr12_-_42878101 0.61 ENST00000552108.1
prickle homolog 1 (Drosophila)
chr3_-_145940214 0.56 ENST00000481701.1
phospholipid scramblase 4
chr17_-_79917645 0.56 ENST00000477214.1
notum pectinacetylesterase homolog (Drosophila)
chr9_-_134151915 0.56 ENST00000372271.3
family with sequence similarity 78, member A
chr9_-_117880477 0.51 ENST00000534839.1
ENST00000340094.3
ENST00000535648.1
ENST00000346706.3
ENST00000345230.3
ENST00000350763.4
tenascin C
chr5_-_38845812 0.45 ENST00000513480.1
ENST00000512519.1
CTD-2127H9.1
chr11_+_111412271 0.41 ENST00000528102.1
layilin
chr3_+_112930946 0.40 ENST00000462425.1
BOC cell adhesion associated, oncogene regulated
chr2_+_17935119 0.38 ENST00000317402.7
GEN1 Holliday junction 5' flap endonuclease
chr12_-_48213735 0.37 ENST00000417902.1
ENST00000417107.1
histone deacetylase 7
chr19_+_57106624 0.37 ENST00000599599.1
zinc finger protein 71
chr17_+_76356516 0.36 ENST00000592569.1
RP11-806H10.4
chr19_+_35225060 0.35 ENST00000599244.1
ENST00000392232.3
zinc finger protein 181
chr19_+_15783879 0.34 ENST00000551607.1
cytochrome P450, family 4, subfamily F, polypeptide 12
chr10_+_35484793 0.34 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
cAMP responsive element modulator
chr13_-_34250861 0.34 ENST00000445227.1
ENST00000454681.2
RP11-141M1.3
chr22_-_39637135 0.33 ENST00000440375.1
platelet-derived growth factor beta polypeptide
chr16_+_14396121 0.32 ENST00000570945.1
RP11-65J21.3
chr12_+_56414851 0.32 ENST00000547167.1
IKAROS family zinc finger 4 (Eos)
chr19_+_35168633 0.32 ENST00000505365.2
zinc finger protein 302
chr12_-_7245018 0.31 ENST00000543835.1
ENST00000535233.2
complement component 1, r subcomponent
chr6_+_131571535 0.31 ENST00000474850.2
A kinase (PRKA) anchor protein 7
chr1_+_155006300 0.30 ENST00000295542.1
ENST00000392480.1
ENST00000423025.2
ENST00000368419.2
DC-STAMP domain containing 1
chr10_+_72194585 0.29 ENST00000420338.2
Uncharacterized protein
chr6_+_84222220 0.29 ENST00000369700.3
protease, serine, 35
chr2_+_87754989 0.29 ENST00000409898.2
ENST00000419680.2
ENST00000414584.1
ENST00000455131.1
long intergenic non-protein coding RNA 152
chr6_-_18264706 0.28 ENST00000244776.7
ENST00000503715.1
DEK oncogene
chr2_+_87755054 0.28 ENST00000423846.1
long intergenic non-protein coding RNA 152
chr19_-_56904799 0.28 ENST00000589895.1
ENST00000589143.1
ENST00000301310.4
ENST00000586929.1
zinc finger protein 582
chr12_-_133050726 0.28 ENST00000595994.1
mucin 8
chr16_+_30934376 0.27 ENST00000562798.1
ENST00000471231.2
F-box and leucine-rich repeat protein 19
chr1_+_16083098 0.27 ENST00000496928.2
ENST00000508310.1
filamin binding LIM protein 1
chr16_+_48657361 0.27 ENST00000565072.1
RP11-42I10.1
chr19_+_10197463 0.26 ENST00000590378.1
ENST00000397881.3
chromosome 19 open reading frame 66
chr3_+_122399697 0.26 ENST00000494811.1
poly (ADP-ribose) polymerase family, member 14
chr12_+_56325231 0.25 ENST00000549368.1
diacylglycerol kinase, alpha 80kDa
chr6_+_292253 0.25 ENST00000603453.1
ENST00000605315.1
ENST00000603881.1
dual specificity phosphatase 22
chr12_-_7244469 0.25 ENST00000538050.1
ENST00000536053.2
complement component 1, r subcomponent
chr12_+_56324933 0.24 ENST00000549629.1
ENST00000555218.1
diacylglycerol kinase, alpha 80kDa
chr8_-_102803163 0.24 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
neurocalcin delta
chr4_-_155511887 0.24 ENST00000302053.3
ENST00000403106.3
fibrinogen alpha chain
chr3_-_148939598 0.24 ENST00000455472.3
ceruloplasmin (ferroxidase)
chr22_-_31536480 0.23 ENST00000215885.3
phospholipase A2, group III
chrX_+_106045891 0.23 ENST00000357242.5
ENST00000310452.2
ENST00000481617.2
ENST00000276175.3
TBC1 domain family, member 8B (with GRAM domain)
chr5_-_111092930 0.23 ENST00000257435.7
neuronal regeneration related protein
chr1_+_59250815 0.23 ENST00000544621.1
ENST00000419531.2
long intergenic non-protein coding RNA 1135
chr6_+_159290917 0.23 ENST00000367072.1
chromosome 6 open reading frame 99
chr19_+_35168567 0.23 ENST00000457781.2
ENST00000505163.1
ENST00000505242.1
ENST00000423823.2
ENST00000507959.1
ENST00000446502.2
zinc finger protein 302
chr12_+_56414795 0.23 ENST00000431367.2
IKAROS family zinc finger 4 (Eos)
chr12_-_11175219 0.22 ENST00000390673.2
taste receptor, type 2, member 19
chr4_+_86396321 0.21 ENST00000503995.1
Rho GTPase activating protein 24
chr16_-_74734672 0.21 ENST00000306247.7
ENST00000575686.1
mixed lineage kinase domain-like
chr9_+_70971815 0.21 ENST00000396392.1
ENST00000396396.1
phosphoglucomutase 5
chr12_-_10007448 0.21 ENST00000538152.1
C-type lectin domain family 2, member B
chr1_+_26759295 0.21 ENST00000430232.1
dehydrodolichyl diphosphate synthase
chr6_-_45544507 0.21 ENST00000563807.1
RP1-166H4.2
chr3_-_4793274 0.20 ENST00000414938.1
eosinophil granule ontogeny transcript (non-protein coding)
chr11_+_71710648 0.20 ENST00000260049.5
interleukin 18 binding protein
chr19_-_10613862 0.20 ENST00000592055.1
kelch-like ECH-associated protein 1
chr19_-_10613361 0.19 ENST00000591039.1
ENST00000591419.1
kelch-like ECH-associated protein 1
chr16_+_72088376 0.19 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
haptoglobin
haptoglobin-related protein
chr11_+_71710973 0.19 ENST00000393707.4
interleukin 18 binding protein
chr12_-_42877726 0.18 ENST00000548696.1
prickle homolog 1 (Drosophila)
chr2_-_204398141 0.18 ENST00000428637.1
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr16_-_90096309 0.18 ENST00000408886.2
chromosome 16 open reading frame 3
chr21_-_34915123 0.18 ENST00000438059.1
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chr10_+_6625733 0.18 ENST00000607982.1
ENST00000608526.1
PRKCQ antisense RNA 1
chr10_+_81065975 0.18 ENST00000446377.2
zinc finger, MIZ-type containing 1
chr2_-_17935059 0.18 ENST00000448223.2
ENST00000381272.4
ENST00000351948.4
structural maintenance of chromosomes 6
chr19_-_44405941 0.18 ENST00000587128.1
RP11-15A1.3
chr8_-_82645082 0.18 ENST00000523361.1
zinc finger, AN1-type domain 1
chr8_-_42358742 0.17 ENST00000517366.1
solute carrier family 20 (phosphate transporter), member 2
chr5_+_40841410 0.17 ENST00000381677.3
caspase recruitment domain family, member 6
chr1_+_40997233 0.17 ENST00000372699.3
ENST00000372697.3
ENST00000372696.3
zinc finger protein 684
chr15_+_71185148 0.17 ENST00000443425.2
ENST00000560755.1
leucine rich repeat containing 49
chr10_-_99771079 0.17 ENST00000309155.3
cartilage acidic protein 1
chr19_-_4540486 0.17 ENST00000306390.6
leucine-rich alpha-2-glycoprotein 1
chr19_+_10381769 0.17 ENST00000423829.2
ENST00000588645.1
intercellular adhesion molecule 1
chr17_-_34207295 0.17 ENST00000463941.1
ENST00000293272.3
chemokine (C-C motif) ligand 5
chr9_-_117853297 0.17 ENST00000542877.1
ENST00000537320.1
ENST00000341037.4
tenascin C
chr20_-_18774614 0.17 ENST00000412553.1
long intergenic non-protein coding RNA 652
chr2_-_165630264 0.17 ENST00000452626.1
cordon-bleu WH2 repeat protein-like 1
chr12_+_58138664 0.17 ENST00000257910.3
tetraspanin 31
chr1_+_42619070 0.16 ENST00000372581.1
guanylate cyclase activator 2B (uroguanylin)
chr19_+_56905024 0.16 ENST00000591172.1
ENST00000589888.1
ENST00000587979.1
ENST00000585659.1
ENST00000593109.1
ZNF582 antisense RNA 1 (head to head)
chr17_-_78428487 0.16 ENST00000562672.2
CTD-2526A2.2
chr17_+_42385927 0.16 ENST00000426726.3
ENST00000590941.1
ENST00000225441.7
RUN domain containing 3A
chr6_+_31730773 0.16 ENST00000415669.2
ENST00000425424.1
suppressor APC domain containing 1
chr11_-_62609281 0.16 ENST00000525239.1
ENST00000538098.2
WD repeat domain 74
chr6_+_63921399 0.16 ENST00000356170.3
FK506 binding protein 1C
chr6_+_32821924 0.16 ENST00000374859.2
ENST00000453265.2
proteasome (prosome, macropain) subunit, beta type, 9
chr3_+_136537911 0.15 ENST00000393079.3
solute carrier family 35, member G2
chr7_-_54826869 0.15 ENST00000450622.1
Sec61 gamma subunit
chr17_+_74729060 0.15 ENST00000587459.1
Uncharacterized protein
chr21_+_34602377 0.15 ENST00000342101.3
ENST00000413881.1
ENST00000443073.1
interferon (alpha, beta and omega) receptor 2
chr22_-_37640456 0.15 ENST00000405484.1
ENST00000441619.1
ENST00000406508.1
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr5_-_140013241 0.15 ENST00000519715.1
CD14 molecule
chr6_+_44126545 0.15 ENST00000532171.1
ENST00000398776.1
ENST00000542245.1
calpain 11
chr14_-_38036271 0.15 ENST00000556024.1
RP11-356O9.2
chr3_+_62304712 0.15 ENST00000494481.1
chromosome 3 open reading frame 14
chr17_+_19030782 0.15 ENST00000344415.4
ENST00000577213.1
GRB2-related adaptor protein-like
chr14_-_50506589 0.14 ENST00000553914.2
RP11-58E21.3
chr1_-_2706236 0.14 ENST00000401095.3
ENST00000574621.2
tetratricopeptide repeat domain 34
chr19_-_11688260 0.14 ENST00000590832.1
acid phosphatase 5, tartrate resistant
chr3_+_45430105 0.14 ENST00000430399.1
leucyl-tRNA synthetase 2, mitochondrial
chr17_-_42994283 0.13 ENST00000593179.1
glial fibrillary acidic protein
chr3_-_160117035 0.13 ENST00000489004.1
ENST00000496589.1
intraflagellar transport 80 homolog (Chlamydomonas)
chr11_-_65363259 0.13 ENST00000342202.4
potassium channel, subfamily K, member 7
chr14_+_24407940 0.13 ENST00000354854.1
DHRS4-AS1
chr22_-_39636914 0.13 ENST00000381551.4
platelet-derived growth factor beta polypeptide
chr3_+_62304648 0.13 ENST00000462069.1
ENST00000232519.5
ENST00000465142.1
chromosome 3 open reading frame 14
chrX_-_20237059 0.13 ENST00000457145.1
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr19_+_40503013 0.13 ENST00000595225.1
zinc finger protein 546
chr17_-_26697304 0.13 ENST00000536498.1
vitronectin
chr10_-_6622201 0.13 ENST00000539722.1
ENST00000397176.2
protein kinase C, theta
chr6_+_44194762 0.13 ENST00000371708.1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr19_+_40502938 0.12 ENST00000599504.1
ENST00000596894.1
ENST00000601138.1
ENST00000600094.1
ENST00000347077.4
zinc finger protein 546
chr2_-_96926313 0.12 ENST00000435268.1
transmembrane protein 127
chr11_-_82997013 0.12 ENST00000529073.1
ENST00000529611.1
coiled-coil domain containing 90B
chr14_-_92414294 0.12 ENST00000554468.1
fibulin 5
chr6_+_292051 0.12 ENST00000344450.5
dual specificity phosphatase 22
chr1_-_153521597 0.12 ENST00000368712.1
S100 calcium binding protein A3
chr7_-_54826920 0.12 ENST00000395535.3
ENST00000352861.4
Sec61 gamma subunit
chr3_-_93692681 0.12 ENST00000348974.4
protein S (alpha)
chr14_+_45605157 0.12 ENST00000542564.2
Fanconi anemia, complementation group M
chr17_-_19265855 0.12 ENST00000440841.1
ENST00000395615.1
ENST00000461069.2
B9 protein domain 1
chr8_-_7320974 0.12 ENST00000528943.1
ENST00000359758.5
ENST00000361111.2
ENST00000398462.2
ENST00000297498.2
ENST00000317900.5
sperm associated antigen 11B
chr12_-_11184006 0.12 ENST00000390675.2
taste receptor, type 2, member 31
chr16_-_20338748 0.12 ENST00000575582.1
ENST00000341642.5
ENST00000381362.4
ENST00000572347.1
ENST00000572478.1
ENST00000302555.5
glycoprotein 2 (zymogen granule membrane)
chr5_+_169758393 0.12 ENST00000521471.1
ENST00000518357.1
ENST00000436248.3
CTB-114C7.3
chr14_+_45605127 0.12 ENST00000556036.1
ENST00000267430.5
Fanconi anemia, complementation group M
chr5_-_145214893 0.12 ENST00000394450.2
PRELI domain containing 2
chr10_+_129785536 0.11 ENST00000419012.2
protein tyrosine phosphatase, receptor type, E
chr4_+_86396265 0.11 ENST00000395184.1
Rho GTPase activating protein 24
chr4_+_41937131 0.11 ENST00000504986.1
ENST00000508448.1
ENST00000513702.1
ENST00000325094.5
transmembrane protein 33
chr9_+_136287444 0.11 ENST00000355699.2
ENST00000356589.2
ENST00000371911.3
ADAM metallopeptidase with thrombospondin type 1 motif, 13
chr3_+_45067659 0.11 ENST00000296130.4
C-type lectin domain family 3, member B
chr1_+_6845384 0.11 ENST00000303635.7
calmodulin binding transcription activator 1
chr6_+_139349903 0.11 ENST00000461027.1
ABRA C-terminal like
chr14_+_88471468 0.11 ENST00000267549.3
G protein-coupled receptor 65
chr2_-_17935027 0.11 ENST00000446852.1
structural maintenance of chromosomes 6
chr22_-_31503490 0.11 ENST00000400299.2
Selenoprotein M
chr3_+_156799587 0.11 ENST00000469196.1
RP11-6F2.5
chr19_-_1155118 0.11 ENST00000590998.1
strawberry notch homolog 2 (Drosophila)
chr21_+_34602680 0.11 ENST00000447980.1
interferon (alpha, beta and omega) receptor 2
chr5_-_111093406 0.11 ENST00000379671.3
neuronal regeneration related protein
chr19_-_15590306 0.11 ENST00000292609.4
peptidoglycan recognition protein 2
chr12_+_56618102 0.11 ENST00000267023.4
ENST00000380198.2
ENST00000341463.5
nucleic acid binding protein 2
chr11_+_73000449 0.11 ENST00000535931.1
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr14_-_81408031 0.11 ENST00000216517.6
centrosomal protein 128kDa
chr6_-_18265050 0.11 ENST00000397239.3
DEK oncogene
chr22_-_41258074 0.11 ENST00000307221.4
DnaJ (Hsp40) homolog, subfamily B, member 7
chr5_-_67730240 0.11 ENST00000507733.1
CTC-537E7.3
chr11_-_82997420 0.11 ENST00000455220.2
ENST00000529689.1
coiled-coil domain containing 90B
chr2_-_99797473 0.11 ENST00000409107.1
ENST00000289359.2
MIT, microtubule interacting and transport, domain containing 1
chr19_-_16606988 0.11 ENST00000269881.3
calreticulin 3
chr17_-_41132088 0.11 ENST00000591916.1
ENST00000451885.2
ENST00000454303.1
prostaglandin E synthase 3 (cytosolic)-like
PTGES3L-AARSD1 readthrough
chr3_-_160117301 0.11 ENST00000326448.7
ENST00000498409.1
ENST00000475677.1
ENST00000478536.1
intraflagellar transport 80 homolog (Chlamydomonas)
chr17_+_77021702 0.11 ENST00000392445.2
ENST00000354124.3
C1q and tumor necrosis factor related protein 1
chr16_-_66907139 0.11 ENST00000561579.2
NEDD8 activating enzyme E1 subunit 1
chr19_-_55672037 0.10 ENST00000588076.1
dynein, axonemal, assembly factor 3
chr6_-_110012380 0.10 ENST00000424296.2
ENST00000341338.6
ENST00000368948.2
ENST00000285397.5
adenylate kinase 9
chr11_-_8290263 0.10 ENST00000428101.2
LIM domain only 1 (rhombotin 1)
chr4_+_40194609 0.10 ENST00000508513.1
ras homolog family member H
chr5_-_22853429 0.10 ENST00000504376.2
cadherin 12, type 2 (N-cadherin 2)
chr14_-_81408063 0.10 ENST00000557411.1
centrosomal protein 128kDa
chr14_+_56127960 0.10 ENST00000553624.1
kinectin 1 (kinesin receptor)
chr4_+_3344141 0.10 ENST00000306648.7
regulator of G-protein signaling 12
chr6_-_127840048 0.10 ENST00000467753.1
SOGA family member 3
chr8_+_7705398 0.10 ENST00000400125.2
ENST00000434307.2
ENST00000326558.5
ENST00000351436.4
ENST00000528033.1
sperm associated antigen 11A
chr2_-_172967621 0.10 ENST00000234198.4
ENST00000466293.2
distal-less homeobox 2
chr18_-_67629015 0.10 ENST00000579496.1
CD226 molecule
chr19_-_44405623 0.10 ENST00000591815.1
RP11-15A1.3
chr13_+_74805561 0.10 ENST00000419499.1
long intergenic non-protein coding RNA 402
chr8_+_27629459 0.10 ENST00000523566.1
establishment of sister chromatid cohesion N-acetyltransferase 2
chr12_+_53443963 0.10 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
tensin like C1 domain containing phosphatase (tensin 2)
chr19_+_10196981 0.10 ENST00000591813.1
chromosome 19 open reading frame 66
chr1_-_161208013 0.10 ENST00000515452.1
ENST00000367983.4
nuclear receptor subfamily 1, group I, member 3
chr1_+_153631130 0.10 ENST00000368685.5
SNAP-associated protein
chr2_-_99797390 0.10 ENST00000422537.2
MIT, microtubule interacting and transport, domain containing 1
chr19_-_7167989 0.10 ENST00000600492.1
insulin receptor
chr4_-_1657135 0.10 ENST00000489029.1
family with sequence similarity 53, member A
chr2_-_106013207 0.10 ENST00000447958.1
four and a half LIM domains 2
chr11_-_82997371 0.10 ENST00000525503.1
coiled-coil domain containing 90B
chr14_-_24553834 0.10 ENST00000397002.2
neural retina leucine zipper
chr7_+_155755248 0.10 ENST00000377722.2
Uncharacterized protein
chr15_+_75335604 0.10 ENST00000563393.1
phosphopantothenoylcysteine decarboxylase
chr3_+_118905564 0.10 ENST00000460625.1
uroplakin 1B
chr19_+_18530184 0.10 ENST00000601357.2
single stranded DNA binding protein 4
chr5_+_93954039 0.09 ENST00000265140.5
ankyrin repeat domain 32
chrX_-_138914394 0.09 ENST00000327569.3
ENST00000361648.2
ENST00000370543.1
ENST00000359686.2
ATPase, class VI, type 11C
chr22_-_50970919 0.09 ENST00000329363.4
ENST00000437588.1
outer dense fiber of sperm tails 3B

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT1_STAT3_BCL6

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:1990697 protein depalmitoleylation(GO:1990697)
0.2 0.7 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.2 0.6 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.1 0.7 GO:2000691 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.1 0.4 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.1 0.3 GO:0003095 pressure natriuresis(GO:0003095)
0.1 0.5 GO:0072255 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.1 0.7 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 1.8 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 0.2 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.2 GO:0061570 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.1 0.2 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 0.2 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.0 0.1 GO:1902824 positive regulation of late endosome to lysosome transport(GO:1902824)
0.0 2.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.1 GO:2000909 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.1 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.1 GO:0032826 natural killer cell differentiation involved in immune response(GO:0002325) regulation of natural killer cell differentiation involved in immune response(GO:0032826)
0.0 0.2 GO:0071727 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.1 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.1 GO:0035712 T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
0.0 0.1 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 0.3 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.2 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.0 0.1 GO:0006429 leucyl-tRNA aminoacylation(GO:0006429)
0.0 0.1 GO:2000852 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.0 0.2 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
0.0 0.6 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0015864 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.0 0.1 GO:1990535 neuron projection maintenance(GO:1990535)
0.0 0.1 GO:0045872 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.4 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.2 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.0 0.4 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.0 0.3 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.1 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.1 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.4 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 0.1 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.1 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.0 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.0 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.4 GO:1900115 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.0 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.0 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.1 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.3 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.0 GO:0030070 insulin processing(GO:0030070)
0.0 0.2 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.8 GO:0006953 acute-phase response(GO:0006953)
0.0 0.0 GO:0061461 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.0 0.0 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.2 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.0 GO:0001807 regulation of type IV hypersensitivity(GO:0001807)
0.0 0.1 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0 0.2 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.0 GO:0032242 regulation of nucleoside transport(GO:0032242)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.0 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.1 GO:0070092 glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.3 GO:0006825 copper ion transport(GO:0006825)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 0.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.9 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.3 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.1 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.2 GO:0071953 elastic fiber(GO:0071953)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.0 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.2 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.0 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.0 0.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 1.4 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.1 0.4 GO:0042007 interleukin-18 binding(GO:0042007)
0.1 0.3 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.1 0.2 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.1 0.7 GO:0045545 syndecan binding(GO:0045545)
0.1 0.3 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 0.3 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.1 0.2 GO:0030492 hemoglobin binding(GO:0030492)
0.1 0.2 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.1 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0004905 type I interferon receptor activity(GO:0004905)
0.0 0.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.0 0.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.0 0.6 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0004823 leucine-tRNA ligase activity(GO:0004823)
0.0 0.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0043337 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.2 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.0 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.1 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 2.2 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 1.0 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.1 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.1 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.5 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.2 PID IL4 2PATHWAY IL4-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.0 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.2 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1