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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for STAT4

Z-value: 0.76

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Transcription factors associated with STAT4

Gene Symbol Gene ID Gene Info
STAT4
ENSG00000138378.13 signal transducer and activator of transcription 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
STAT4hg19_v2_chr2_-_192015697_1920157430.891.8e-02Click!

Activity profile of STAT4 motif

Sorted Z-values of STAT4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_127039075 1.44 ENST00000514853.2
CTC-228N24.1
CTC-228N24.1
chr19_+_35225121 0.90 ENST00000595708.1
ENST00000593781.1
ZNF181
zinc finger protein 181
chr11_+_12302492 0.72 ENST00000533534.1
MICALCL
MICAL C-terminal like
chr4_+_169575875 0.63 ENST00000503457.1
PALLD
palladin, cytoskeletal associated protein
chr19_+_44331555 0.63 ENST00000590950.1
ZNF283
zinc finger protein 283
chr3_-_196242233 0.59 ENST00000397537.2
SMCO1
single-pass membrane protein with coiled-coil domains 1
chr19_-_59084647 0.56 ENST00000594234.1
ENST00000596039.1
MZF1
myeloid zinc finger 1
chr11_-_111636772 0.50 ENST00000531373.1
PPP2R1B
protein phosphatase 2, regulatory subunit A, beta
chr12_+_133656995 0.49 ENST00000356456.5
ZNF140
zinc finger protein 140
chr7_+_55980331 0.49 ENST00000429591.2
ZNF713
zinc finger protein 713
chr3_+_111260980 0.49 ENST00000438817.2
CD96
CD96 molecule
chrX_+_107288239 0.48 ENST00000217957.5
VSIG1
V-set and immunoglobulin domain containing 1
chrX_+_107288197 0.46 ENST00000415430.3
VSIG1
V-set and immunoglobulin domain containing 1
chr19_-_51875894 0.46 ENST00000600427.1
ENST00000595217.1
ENST00000221978.5
NKG7
natural killer cell group 7 sequence
chr19_+_44617511 0.46 ENST00000262894.6
ENST00000588926.1
ENST00000592780.1
ZNF225
zinc finger protein 225
chr5_-_111093081 0.43 ENST00000453526.2
ENST00000509427.1
NREP
neuronal regeneration related protein
chr16_+_66600294 0.42 ENST00000535705.1
ENST00000332695.7
ENST00000336328.6
ENST00000528324.1
ENST00000531885.1
ENST00000529506.1
ENST00000457188.2
ENST00000533666.1
ENST00000533953.1
ENST00000379500.2
ENST00000328020.6
CMTM1
CKLF-like MARVEL transmembrane domain containing 1
chr13_-_30160925 0.41 ENST00000450494.1
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr2_+_234294585 0.38 ENST00000447484.1
DGKD
diacylglycerol kinase, delta 130kDa
chr3_+_50649302 0.38 ENST00000446044.1
MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr16_-_1660662 0.37 ENST00000569646.1
IFT140
intraflagellar transport 140 homolog (Chlamydomonas)
chr19_-_56904799 0.36 ENST00000589895.1
ENST00000589143.1
ENST00000301310.4
ENST00000586929.1
ZNF582
zinc finger protein 582
chr1_-_161279749 0.36 ENST00000533357.1
ENST00000360451.6
ENST00000336559.4
MPZ
myelin protein zero
chr4_-_140477353 0.36 ENST00000406354.1
ENST00000506866.2
SETD7
SET domain containing (lysine methyltransferase) 7
chr16_+_85932760 0.35 ENST00000565552.1
IRF8
interferon regulatory factor 8
chr12_+_113587558 0.34 ENST00000335621.6
CCDC42B
coiled-coil domain containing 42B
chr6_+_35995552 0.32 ENST00000468133.1
MAPK14
mitogen-activated protein kinase 14
chr19_+_35168547 0.32 ENST00000502743.1
ENST00000509528.1
ENST00000506901.1
ZNF302
zinc finger protein 302
chr11_+_65657875 0.31 ENST00000312579.2
CCDC85B
coiled-coil domain containing 85B
chr17_-_46682321 0.31 ENST00000225648.3
ENST00000484302.2
HOXB6
homeobox B6
chr10_-_95241951 0.31 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
MYOF
myoferlin
chr20_+_5731083 0.30 ENST00000445603.1
ENST00000442185.1
C20orf196
chromosome 20 open reading frame 196
chr1_+_149754227 0.29 ENST00000444948.1
ENST00000369168.4
FCGR1A
Fc fragment of IgG, high affinity Ia, receptor (CD64)
chr1_-_161337662 0.29 ENST00000367974.1
C1orf192
chromosome 1 open reading frame 192
chr10_+_6625605 0.29 ENST00000414894.1
ENST00000449648.1
PRKCQ-AS1
PRKCQ antisense RNA 1
chr14_-_100841794 0.29 ENST00000556295.1
ENST00000554820.1
WARS
tryptophanyl-tRNA synthetase
chr4_-_76957214 0.29 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr11_+_117070904 0.29 ENST00000529792.1
TAGLN
transgelin
chr1_+_155146318 0.28 ENST00000368385.4
ENST00000545012.1
ENST00000392451.2
ENST00000368383.3
ENST00000368382.1
ENST00000334634.4
TRIM46
tripartite motif containing 46
chr1_-_226065330 0.27 ENST00000436966.1
TMEM63A
transmembrane protein 63A
chr3_+_15469058 0.27 ENST00000432764.2
EAF1
ELL associated factor 1
chr14_-_100841930 0.26 ENST00000555031.1
ENST00000553395.1
ENST00000553545.1
ENST00000344102.5
ENST00000556338.1
ENST00000392882.2
ENST00000553934.1
WARS
tryptophanyl-tRNA synthetase
chr10_-_95242044 0.26 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
MYOF
myoferlin
chr5_+_667759 0.26 ENST00000594226.1
AC026740.1
Uncharacterized protein
chr14_-_100841670 0.26 ENST00000557297.1
ENST00000555813.1
ENST00000557135.1
ENST00000556698.1
ENST00000554509.1
ENST00000555410.1
WARS
tryptophanyl-tRNA synthetase
chr20_+_9049742 0.26 ENST00000437503.1
PLCB4
phospholipase C, beta 4
chr3_-_187455680 0.25 ENST00000438077.1
BCL6
B-cell CLL/lymphoma 6
chr17_-_42994283 0.25 ENST00000593179.1
GFAP
glial fibrillary acidic protein
chr12_+_26164645 0.25 ENST00000542004.1
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr1_+_17906970 0.25 ENST00000375415.1
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr18_+_20714525 0.24 ENST00000400473.2
CABLES1
Cdk5 and Abl enzyme substrate 1
chr3_+_45429998 0.23 ENST00000265537.3
ENST00000415258.1
ENST00000431023.1
ENST00000414984.1
LARS2
leucyl-tRNA synthetase 2, mitochondrial
chrX_-_63005405 0.23 ENST00000374878.1
ENST00000437457.2
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr8_+_38586068 0.22 ENST00000443286.2
ENST00000520340.1
ENST00000518415.1
TACC1
transforming, acidic coiled-coil containing protein 1
chr19_+_50145328 0.22 ENST00000360565.3
SCAF1
SR-related CTD-associated factor 1
chr17_+_41132564 0.22 ENST00000361677.1
ENST00000589705.1
RUNDC1
RUN domain containing 1
chr11_+_6411670 0.21 ENST00000530395.1
ENST00000527275.1
SMPD1
sphingomyelin phosphodiesterase 1, acid lysosomal
chr1_+_202431859 0.21 ENST00000391959.3
ENST00000367270.4
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr17_-_27038063 0.21 ENST00000439862.3
PROCA1
protein interacting with cyclin A1
chr3_+_171561127 0.21 ENST00000334567.5
ENST00000450693.1
TMEM212
transmembrane protein 212
chr11_+_20044375 0.21 ENST00000525322.1
ENST00000530408.1
NAV2
neuron navigator 2
chr11_+_20044096 0.21 ENST00000533917.1
NAV2
neuron navigator 2
chr6_-_116833500 0.21 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr4_-_140477910 0.20 ENST00000404104.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr14_-_20881579 0.20 ENST00000556935.1
ENST00000262715.5
ENST00000556549.1
TEP1
telomerase-associated protein 1
chr16_-_67260901 0.20 ENST00000341546.3
ENST00000409509.1
ENST00000433915.1
ENST00000454102.2
LRRC29
AC040160.1
leucine rich repeat containing 29
Uncharacterized protein; cDNA FLJ57407, weakly similar to Mus musculus leucine rich repeat containing 29 (Lrrc29), mRNA
chr7_-_41740181 0.20 ENST00000442711.1
INHBA
inhibin, beta A
chr9_-_85882145 0.20 ENST00000328788.1
FRMD3
FERM domain containing 3
chr3_-_155461515 0.20 ENST00000399242.2
AC104472.1
CDNA FLJ26134 fis, clone TMS03713; Uncharacterized protein
chr6_-_32821599 0.20 ENST00000354258.4
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr5_+_137203465 0.19 ENST00000239926.4
MYOT
myotilin
chr15_+_67458357 0.19 ENST00000537194.2
SMAD3
SMAD family member 3
chr19_+_42746927 0.19 ENST00000378108.1
AC006486.1
AC006486.1
chr2_+_175352114 0.19 ENST00000444196.1
ENST00000417038.1
ENST00000606406.1
AC010894.3
AC010894.3
chr17_-_77924627 0.18 ENST00000572862.1
ENST00000573782.1
ENST00000574427.1
ENST00000570373.1
ENST00000340848.7
ENST00000576768.1
TBC1D16
TBC1 domain family, member 16
chr2_-_190044480 0.18 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr3_-_126327398 0.18 ENST00000383572.2
TXNRD3NB
thioredoxin reductase 3 neighbor
chr5_+_140261703 0.18 ENST00000409494.1
ENST00000289272.2
PCDHA13
protocadherin alpha 13
chr4_-_187476721 0.17 ENST00000307161.5
MTNR1A
melatonin receptor 1A
chr6_+_108977520 0.17 ENST00000540898.1
FOXO3
forkhead box O3
chr5_+_140753444 0.17 ENST00000517434.1
PCDHGA6
protocadherin gamma subfamily A, 6
chr2_+_177502438 0.17 ENST00000443670.1
AC017048.4
long intergenic non-protein coding RNA 1117
chr1_-_144994840 0.16 ENST00000369351.3
ENST00000369349.3
PDE4DIP
phosphodiesterase 4D interacting protein
chr5_+_137203541 0.16 ENST00000421631.2
MYOT
myotilin
chr1_-_8000872 0.16 ENST00000377507.3
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr5_-_151066514 0.16 ENST00000538026.1
ENST00000522348.1
ENST00000521569.1
SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr5_+_40909354 0.16 ENST00000313164.9
C7
complement component 7
chr10_+_104404644 0.16 ENST00000462202.2
TRIM8
tripartite motif containing 8
chr9_-_134585221 0.15 ENST00000372190.3
ENST00000427994.1
RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr15_-_75660919 0.15 ENST00000569482.1
ENST00000565683.1
ENST00000561615.1
ENST00000563622.1
ENST00000568374.1
ENST00000566256.1
ENST00000267978.5
MAN2C1
mannosidase, alpha, class 2C, member 1
chr15_+_63340858 0.15 ENST00000560615.1
TPM1
tropomyosin 1 (alpha)
chr12_-_49245936 0.15 ENST00000308025.3
DDX23
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
chr1_+_9299895 0.14 ENST00000602477.1
H6PD
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr5_+_137203557 0.14 ENST00000515645.1
MYOT
myotilin
chr19_-_39881669 0.13 ENST00000221266.7
PAF1
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr22_+_24551765 0.13 ENST00000337989.7
CABIN1
calcineurin binding protein 1
chr20_-_62738524 0.13 ENST00000369768.1
NPBWR2
neuropeptides B/W receptor 2
chr19_+_57106647 0.13 ENST00000328070.6
ZNF71
zinc finger protein 71
chr10_+_115312825 0.13 ENST00000537906.1
ENST00000541666.1
HABP2
hyaluronan binding protein 2
chr3_+_155838337 0.13 ENST00000490337.1
ENST00000389636.5
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr1_-_231005310 0.12 ENST00000470540.1
C1orf198
chromosome 1 open reading frame 198
chr15_+_63340734 0.12 ENST00000560959.1
TPM1
tropomyosin 1 (alpha)
chr16_+_67261008 0.12 ENST00000304800.9
ENST00000563953.1
ENST00000565201.1
TMEM208
transmembrane protein 208
chr15_+_63340775 0.12 ENST00000559281.1
ENST00000317516.7
TPM1
tropomyosin 1 (alpha)
chr15_+_45021183 0.12 ENST00000559390.1
TRIM69
tripartite motif containing 69
chr8_-_123139423 0.12 ENST00000523792.1
RP11-398G24.2
RP11-398G24.2
chr17_-_41132410 0.12 ENST00000409446.3
ENST00000453594.1
ENST00000409399.1
ENST00000421990.2
PTGES3L
PTGES3L-AARSD1
prostaglandin E synthase 3 (cytosolic)-like
PTGES3L-AARSD1 readthrough
chr16_+_4674814 0.12 ENST00000415496.1
ENST00000587747.1
ENST00000399577.5
ENST00000588994.1
ENST00000586183.1
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr19_-_39881777 0.12 ENST00000595564.1
ENST00000221265.3
PAF1
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr8_-_95274536 0.11 ENST00000297596.2
ENST00000396194.2
GEM
GTP binding protein overexpressed in skeletal muscle
chr2_+_234826016 0.11 ENST00000324695.4
ENST00000433712.2
TRPM8
transient receptor potential cation channel, subfamily M, member 8
chr20_+_42136308 0.11 ENST00000434666.1
ENST00000427442.2
ENST00000439769.1
ENST00000418998.1
L3MBTL1
l(3)mbt-like 1 (Drosophila)
chr10_+_102790980 0.11 ENST00000393459.1
ENST00000224807.5
SFXN3
sideroflexin 3
chr5_+_73109339 0.11 ENST00000296799.4
ARHGEF28
Rho guanine nucleotide exchange factor (GEF) 28
chr11_-_118436707 0.11 ENST00000264020.2
ENST00000264021.3
IFT46
intraflagellar transport 46 homolog (Chlamydomonas)
chr3_-_137851220 0.11 ENST00000236709.3
A4GNT
alpha-1,4-N-acetylglucosaminyltransferase
chr11_+_73003824 0.11 ENST00000538328.1
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr15_-_60690932 0.10 ENST00000559818.1
ANXA2
annexin A2
chr10_-_116444371 0.10 ENST00000533213.2
ENST00000369252.4
ABLIM1
actin binding LIM protein 1
chr22_-_50699701 0.10 ENST00000395780.1
MAPK12
mitogen-activated protein kinase 12
chr20_+_39657454 0.10 ENST00000361337.2
TOP1
topoisomerase (DNA) I
chr19_+_17448348 0.10 ENST00000324894.8
ENST00000358792.7
ENST00000600625.1
GTPBP3
GTP binding protein 3 (mitochondrial)
chr6_+_31540056 0.10 ENST00000418386.2
LTA
lymphotoxin alpha
chr17_-_38210644 0.10 ENST00000394128.2
ENST00000394127.2
ENST00000356271.3
ENST00000535071.2
ENST00000580885.1
ENST00000543759.2
ENST00000537674.2
ENST00000580517.1
ENST00000578161.1
MED24
mediator complex subunit 24
chr6_-_56716686 0.10 ENST00000520645.1
DST
dystonin
chrX_+_54834159 0.10 ENST00000375053.2
ENST00000347546.4
ENST00000375062.4
MAGED2
melanoma antigen family D, 2
chr12_-_49245916 0.09 ENST00000552512.1
ENST00000551468.1
DDX23
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
chr12_-_122658746 0.09 ENST00000377035.1
IL31
interleukin 31
chr14_+_23235886 0.09 ENST00000604262.1
ENST00000431881.2
ENST00000412791.1
ENST00000358043.5
OXA1L
oxidase (cytochrome c) assembly 1-like
chr19_-_7812446 0.09 ENST00000394173.4
ENST00000301357.8
CD209
CD209 molecule
chr17_+_7358889 0.09 ENST00000575379.1
CHRNB1
cholinergic receptor, nicotinic, beta 1 (muscle)
chr16_+_4674787 0.09 ENST00000262370.7
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr1_-_9811600 0.09 ENST00000435891.1
CLSTN1
calsyntenin 1
chr14_+_55034599 0.09 ENST00000392067.3
ENST00000357634.3
SAMD4A
sterile alpha motif domain containing 4A
chr6_-_25874440 0.09 ENST00000361703.6
ENST00000397060.4
SLC17A3
solute carrier family 17 (organic anion transporter), member 3
chr4_-_140477928 0.08 ENST00000274031.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr8_-_110660975 0.08 ENST00000528045.1
SYBU
syntabulin (syntaxin-interacting)
chr16_+_58283814 0.08 ENST00000443128.2
ENST00000219299.4
CCDC113
coiled-coil domain containing 113
chr19_+_44669280 0.08 ENST00000590089.1
ENST00000454662.2
ZNF226
zinc finger protein 226
chr6_+_167525277 0.08 ENST00000400926.2
CCR6
chemokine (C-C motif) receptor 6
chr9_-_34628104 0.08 ENST00000378909.2
ARID3C
AT rich interactive domain 3C (BRIGHT-like)
chr3_-_183735651 0.08 ENST00000427120.2
ENST00000392579.2
ENST00000382494.2
ENST00000446941.2
ABCC5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr14_-_21924209 0.07 ENST00000557364.1
CHD8
chromodomain helicase DNA binding protein 8
chr2_+_68962014 0.07 ENST00000467265.1
ARHGAP25
Rho GTPase activating protein 25
chrX_+_114874727 0.07 ENST00000543070.1
PLS3
plastin 3
chrX_-_70474910 0.07 ENST00000373988.1
ENST00000373998.1
ZMYM3
zinc finger, MYM-type 3
chr5_-_121413974 0.07 ENST00000231004.4
LOX
lysyl oxidase
chr1_+_153651078 0.07 ENST00000368680.3
NPR1
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)
chr19_-_50529193 0.07 ENST00000596445.1
ENST00000599538.1
VRK3
vaccinia related kinase 3
chr16_+_19467772 0.07 ENST00000219821.5
ENST00000561503.1
ENST00000564959.1
TMC5
transmembrane channel-like 5
chr14_+_20811766 0.07 ENST00000250416.5
ENST00000527915.1
PARP2
poly (ADP-ribose) polymerase 2
chr3_-_71114066 0.07 ENST00000485326.2
FOXP1
forkhead box P1
chr1_-_33502528 0.07 ENST00000354858.6
AK2
adenylate kinase 2
chr1_-_33502441 0.07 ENST00000548033.1
ENST00000487289.1
ENST00000373449.2
ENST00000480134.1
ENST00000467905.1
AK2
adenylate kinase 2
chr11_+_128563652 0.06 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr6_-_49712091 0.06 ENST00000371159.4
CRISP3
cysteine-rich secretory protein 3
chr9_-_116837249 0.06 ENST00000466610.2
AMBP
alpha-1-microglobulin/bikunin precursor
chr8_-_27468717 0.06 ENST00000520796.1
ENST00000520491.1
CLU
clusterin
chr19_-_7812397 0.06 ENST00000593660.1
ENST00000354397.6
ENST00000593821.1
ENST00000602261.1
ENST00000315591.8
ENST00000394161.5
ENST00000204801.8
ENST00000601256.1
ENST00000601951.1
ENST00000315599.7
CD209
CD209 molecule
chr5_-_16509101 0.06 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chr3_-_57678772 0.06 ENST00000311128.5
DENND6A
DENN/MADD domain containing 6A
chr8_-_27468842 0.06 ENST00000523500.1
CLU
clusterin
chr11_+_64216546 0.06 ENST00000316124.2
AP003774.4
HCG1652096, isoform CRA_a; Uncharacterized protein; cDNA FLJ37045 fis, clone BRACE2012185
chr3_+_159570722 0.06 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr1_-_144994909 0.06 ENST00000369347.4
ENST00000369354.3
PDE4DIP
phosphodiesterase 4D interacting protein
chr4_-_83933999 0.06 ENST00000510557.1
LIN54
lin-54 homolog (C. elegans)
chrX_+_149861836 0.06 ENST00000542156.1
ENST00000370390.3
ENST00000490316.2
ENST00000445323.2
ENST00000544228.1
ENST00000451863.2
MTMR1
myotubularin related protein 1
chr19_-_58864848 0.05 ENST00000263100.3
A1BG
alpha-1-B glycoprotein
chr5_+_140227048 0.05 ENST00000532602.1
PCDHA9
protocadherin alpha 9
chr14_-_21270561 0.05 ENST00000412779.2
RNASE1
ribonuclease, RNase A family, 1 (pancreatic)
chr1_+_233086326 0.05 ENST00000366628.5
ENST00000366627.4
NTPCR
nucleoside-triphosphatase, cancer-related
chr1_-_211752073 0.05 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr4_+_41258786 0.05 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr14_-_80678512 0.05 ENST00000553968.1
DIO2
deiodinase, iodothyronine, type II
chr15_+_64680003 0.05 ENST00000261884.3
TRIP4
thyroid hormone receptor interactor 4
chr3_+_187871060 0.05 ENST00000448637.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr19_+_39881951 0.05 ENST00000315588.5
ENST00000594368.1
ENST00000599213.2
ENST00000596297.1
MED29
mediator complex subunit 29
chr5_+_34685805 0.05 ENST00000508315.1
RAI14
retinoic acid induced 14
chr9_-_95166884 0.05 ENST00000375561.5
OGN
osteoglycin
chr2_+_68961934 0.05 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chr12_-_11139511 0.05 ENST00000506868.1
TAS2R50
taste receptor, type 2, member 50
chr16_-_67260691 0.05 ENST00000447579.1
ENST00000393992.1
ENST00000424285.1
LRRC29
leucine rich repeat containing 29
chr1_+_9242221 0.05 ENST00000412639.2
RP3-510D11.2
RP3-510D11.2
chr10_-_126847276 0.05 ENST00000531469.1
CTBP2
C-terminal binding protein 2
chr17_-_3417062 0.04 ENST00000570318.1
ENST00000541913.1
SPATA22
spermatogenesis associated 22
chr14_+_35591020 0.04 ENST00000603611.1
KIAA0391
KIAA0391
chr5_-_140013224 0.04 ENST00000498971.2
CD14
CD14 molecule
chr15_-_100882191 0.04 ENST00000268070.4
ADAMTS17
ADAM metallopeptidase with thrombospondin type 1 motif, 17
chr19_-_10613862 0.04 ENST00000592055.1
KEAP1
kelch-like ECH-associated protein 1
chr5_-_127674883 0.04 ENST00000507835.1
FBN2
fibrillin 2
chr2_-_177502254 0.04 ENST00000339037.3
AC017048.3
long intergenic non-protein coding RNA 1116
chr14_+_69658480 0.04 ENST00000409949.1
ENST00000409242.1
ENST00000312994.5
ENST00000413191.1
EXD2
exonuclease 3'-5' domain containing 2
chr6_-_49712072 0.04 ENST00000423399.2
CRISP3
cysteine-rich secretory protein 3
chr14_-_21490653 0.04 ENST00000449431.2
NDRG2
NDRG family member 2
chr14_+_20811722 0.04 ENST00000429687.3
PARP2
poly (ADP-ribose) polymerase 2
chr7_-_115670804 0.04 ENST00000320239.7
TFEC
transcription factor EC
chr19_+_50529212 0.04 ENST00000270617.3
ENST00000445728.3
ENST00000601364.1
ZNF473
zinc finger protein 473
chr6_-_49712123 0.03 ENST00000263045.4
CRISP3
cysteine-rich secretory protein 3
chr17_+_5323492 0.03 ENST00000405578.4
ENST00000574003.1
RPAIN
RPA interacting protein
chr12_+_58138800 0.03 ENST00000547992.1
ENST00000552816.1
ENST00000547472.1
TSPAN31
tetraspanin 31

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.1 0.8 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.2 GO:0006429 leucyl-tRNA aminoacylation(GO:0006429)
0.1 0.2 GO:0046968 peptide antigen transport(GO:0046968)
0.1 0.3 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.1 0.2 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1 0.2 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.2 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.1 0.2 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.4 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.2 GO:0046967 cytosol to ER transport(GO:0046967)
0.0 0.4 GO:0021564 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564)
0.0 0.4 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.6 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.6 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.9 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.2 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.3 GO:0099612 protein localization to axon(GO:0099612)
0.0 0.1 GO:0052360 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.3 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.2 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.2 GO:0023021 termination of signal transduction(GO:0023021)
0.0 0.2 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.0 0.4 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.1 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.1 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.6 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.4 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.5 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.4 GO:0044146 negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.1 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.4 GO:0098743 cell aggregation(GO:0098743)
0.0 0.4 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.2 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.1 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.1 GO:0015747 urate transport(GO:0015747)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 0.2 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.3 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.2 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.4 GO:0032059 muscle thin filament tropomyosin(GO:0005862) bleb(GO:0032059)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.4 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.1 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.3 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.2 GO:0004823 leucine-tRNA ligase activity(GO:0004823)
0.0 0.1 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.0 0.4 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.1 GO:0032093 SAM domain binding(GO:0032093)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.2 GO:0046979 TAP2 binding(GO:0046979)
0.0 0.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.3 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 1.1 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.5 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.2 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0015562 urate transmembrane transporter activity(GO:0015143) efflux transmembrane transporter activity(GO:0015562) salt transmembrane transporter activity(GO:1901702)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.5 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL