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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TBX15_MGA

Z-value: 1.49

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Transcription factors associated with TBX15_MGA

Gene Symbol Gene ID Gene Info
TBX15
ENSG00000092607.9 T-box transcription factor 15
MGA
ENSG00000174197.12 MAX dimerization protein MGA

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX15hg19_v2_chr1_-_119532127_1195321790.721.1e-01Click!
MGAhg19_v2_chr15_+_41952591_41952672-0.305.7e-01Click!

Activity profile of TBX15_MGA motif

Sorted Z-values of TBX15_MGA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_11907829 2.06 ENST00000376480.3
NPPA
natriuretic peptide A
chr3_+_167453493 2.01 ENST00000295777.5
ENST00000472747.2
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr11_+_18477369 1.96 ENST00000396213.3
ENST00000280706.2
LDHAL6A
lactate dehydrogenase A-like 6A
chr2_+_228678550 1.65 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr8_-_145060593 1.64 ENST00000313059.5
ENST00000524918.1
ENST00000313028.7
ENST00000525773.1
PARP10
poly (ADP-ribose) polymerase family, member 10
chr7_-_120497178 1.61 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
TSPAN12
tetraspanin 12
chr11_-_615570 1.53 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
IRF7
interferon regulatory factor 7
chr13_-_48575376 1.40 ENST00000434484.1
SUCLA2
succinate-CoA ligase, ADP-forming, beta subunit
chr19_-_10213335 1.21 ENST00000592641.1
ENST00000253109.4
ANGPTL6
angiopoietin-like 6
chr9_+_96717821 1.17 ENST00000454594.1
RP11-231K24.2
RP11-231K24.2
chr13_-_48575401 1.04 ENST00000433022.1
ENST00000544100.1
SUCLA2
succinate-CoA ligase, ADP-forming, beta subunit
chr14_+_51026844 1.02 ENST00000554886.1
ATL1
atlastin GTPase 1
chr21_+_30502806 0.92 ENST00000399928.1
ENST00000399926.1
MAP3K7CL
MAP3K7 C-terminal like
chr8_-_99954788 0.91 ENST00000523601.1
STK3
serine/threonine kinase 3
chr3_+_167453026 0.90 ENST00000472941.1
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr14_+_95078714 0.89 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr7_-_81635106 0.88 ENST00000443883.1
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr2_+_62933001 0.86 ENST00000263991.5
ENST00000354487.3
EHBP1
EH domain binding protein 1
chr9_+_139847347 0.84 ENST00000371632.3
LCN12
lipocalin 12
chr2_+_62932779 0.84 ENST00000427809.1
ENST00000405482.1
ENST00000431489.1
EHBP1
EH domain binding protein 1
chr14_+_51026926 0.77 ENST00000557735.1
ATL1
atlastin GTPase 1
chr1_+_155911480 0.73 ENST00000368318.3
RXFP4
relaxin/insulin-like family peptide receptor 4
chr5_-_114515734 0.73 ENST00000514154.1
ENST00000282369.3
TRIM36
tripartite motif containing 36
chrM_+_10464 0.69 ENST00000361335.1
MT-ND4L
mitochondrially encoded NADH dehydrogenase 4L
chr3_-_120170052 0.68 ENST00000295633.3
FSTL1
follistatin-like 1
chr4_+_26578293 0.68 ENST00000512840.1
TBC1D19
TBC1 domain family, member 19
chr8_-_99955042 0.66 ENST00000519420.1
STK3
serine/threonine kinase 3
chr5_-_49737184 0.65 ENST00000508934.1
ENST00000303221.5
EMB
embigin
chr13_-_48575443 0.64 ENST00000378654.3
SUCLA2
succinate-CoA ligase, ADP-forming, beta subunit
chrX_+_16804544 0.64 ENST00000380122.5
ENST00000398155.4
TXLNG
taxilin gamma
chr14_-_45603657 0.64 ENST00000396062.3
FKBP3
FK506 binding protein 3, 25kDa
chr3_+_107364769 0.64 ENST00000449271.1
ENST00000425868.1
ENST00000449213.1
BBX
bobby sox homolog (Drosophila)
chr12_+_104324112 0.63 ENST00000299767.5
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr14_+_75746781 0.62 ENST00000555347.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr2_-_39664405 0.62 ENST00000341681.5
ENST00000263881.3
MAP4K3
mitogen-activated protein kinase kinase kinase kinase 3
chr6_-_30815936 0.61 ENST00000442852.1
XXbac-BPG27H4.8
XXbac-BPG27H4.8
chr12_-_90024360 0.60 ENST00000393164.2
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr7_+_107220660 0.60 ENST00000465919.1
ENST00000445771.2
ENST00000479917.1
ENST00000421217.1
ENST00000457837.1
BCAP29
B-cell receptor-associated protein 29
chr19_-_46526304 0.60 ENST00000008938.4
PGLYRP1
peptidoglycan recognition protein 1
chr18_-_45457478 0.59 ENST00000402690.2
ENST00000356825.4
SMAD2
SMAD family member 2
chr4_+_140222609 0.59 ENST00000296543.5
ENST00000398947.1
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr11_+_107643129 0.58 ENST00000447610.1
AP001024.2
Uncharacterized protein
chr1_+_172502244 0.57 ENST00000610051.1
SUCO
SUN domain containing ossification factor
chr11_+_46402482 0.56 ENST00000441869.1
MDK
midkine (neurite growth-promoting factor 2)
chr3_+_142315225 0.55 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
PLS1
plastin 1
chrM_+_8366 0.55 ENST00000361851.1
MT-ATP8
mitochondrially encoded ATP synthase 8
chr11_+_46402297 0.55 ENST00000405308.2
MDK
midkine (neurite growth-promoting factor 2)
chr11_-_85430204 0.54 ENST00000389958.3
ENST00000527794.1
SYTL2
synaptotagmin-like 2
chr2_-_74776586 0.54 ENST00000420535.1
LOXL3
lysyl oxidase-like 3
chr10_+_94451574 0.53 ENST00000492654.2
HHEX
hematopoietically expressed homeobox
chr1_+_172502336 0.53 ENST00000263688.3
SUCO
SUN domain containing ossification factor
chr1_+_150254936 0.52 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
C1orf51
chromosome 1 open reading frame 51
chr12_+_56473939 0.52 ENST00000450146.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr1_+_93544821 0.51 ENST00000370303.4
MTF2
metal response element binding transcription factor 2
chr11_+_111749650 0.51 ENST00000528125.1
C11orf1
chromosome 11 open reading frame 1
chr1_+_26737253 0.51 ENST00000326279.6
LIN28A
lin-28 homolog A (C. elegans)
chr12_+_52431016 0.51 ENST00000553200.1
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr11_-_85779971 0.51 ENST00000393346.3
PICALM
phosphatidylinositol binding clathrin assembly protein
chr14_+_51026743 0.51 ENST00000358385.6
ENST00000357032.3
ENST00000354525.4
ATL1
atlastin GTPase 1
chrM_+_10758 0.51 ENST00000361381.2
MT-ND4
mitochondrially encoded NADH dehydrogenase 4
chr3_-_167452614 0.51 ENST00000392750.2
ENST00000464360.1
ENST00000492139.1
ENST00000471885.1
ENST00000470131.1
PDCD10
programmed cell death 10
chr10_-_16563870 0.48 ENST00000298943.3
C1QL3
complement component 1, q subcomponent-like 3
chr14_+_90864504 0.48 ENST00000544280.2
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr2_-_145090035 0.48 ENST00000542155.1
ENST00000241391.5
ENST00000463875.2
GTDC1
glycosyltransferase-like domain containing 1
chr5_+_74807581 0.47 ENST00000241436.4
ENST00000352007.5
POLK
polymerase (DNA directed) kappa
chr5_+_74807886 0.47 ENST00000514296.1
POLK
polymerase (DNA directed) kappa
chr1_+_35734616 0.47 ENST00000441447.1
ZMYM4
zinc finger, MYM-type 4
chr15_-_34502278 0.46 ENST00000559515.1
ENST00000256544.3
ENST00000560108.1
ENST00000559462.1
KATNBL1
katanin p80 subunit B-like 1
chr2_+_154728426 0.46 ENST00000392825.3
ENST00000434213.1
GALNT13
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13)
chr12_-_111180644 0.46 ENST00000551676.1
ENST00000550991.1
ENST00000335007.5
ENST00000340766.5
PPP1CC
protein phosphatase 1, catalytic subunit, gamma isozyme
chr1_-_27701307 0.45 ENST00000270879.4
ENST00000354982.2
FCN3
ficolin (collagen/fibrinogen domain containing) 3
chr3_+_142315294 0.45 ENST00000464320.1
PLS1
plastin 1
chr4_+_183065793 0.45 ENST00000512480.1
TENM3
teneurin transmembrane protein 3
chr9_+_17134980 0.45 ENST00000380647.3
CNTLN
centlein, centrosomal protein
chr8_-_109260897 0.44 ENST00000521297.1
ENST00000519030.1
ENST00000521440.1
ENST00000518345.1
ENST00000519627.1
ENST00000220849.5
EIF3E
eukaryotic translation initiation factor 3, subunit E
chr16_-_69418553 0.44 ENST00000569542.2
TERF2
telomeric repeat binding factor 2
chr3_+_107364683 0.44 ENST00000413213.1
BBX
bobby sox homolog (Drosophila)
chr7_+_133261209 0.43 ENST00000545148.1
EXOC4
exocyst complex component 4
chr6_+_53794780 0.41 ENST00000505762.1
ENST00000511369.1
ENST00000431554.2
MLIP
RP11-411K7.1
muscular LMNA-interacting protein
RP11-411K7.1
chrX_+_123095546 0.41 ENST00000371157.3
ENST00000371145.3
ENST00000371144.3
STAG2
stromal antigen 2
chr11_-_85430088 0.41 ENST00000533057.1
ENST00000533892.1
SYTL2
synaptotagmin-like 2
chr3_-_167452703 0.41 ENST00000497056.2
ENST00000473645.2
PDCD10
programmed cell death 10
chr11_+_73358690 0.40 ENST00000545798.1
ENST00000539157.1
ENST00000546251.1
ENST00000535582.1
ENST00000538227.1
ENST00000543524.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr22_-_41215291 0.40 ENST00000542412.1
ENST00000544408.1
SLC25A17
solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
chr17_+_9066252 0.39 ENST00000436734.1
NTN1
netrin 1
chr11_+_10772847 0.39 ENST00000524523.1
CTR9
CTR9, Paf1/RNA polymerase II complex component
chr6_+_108616243 0.39 ENST00000421954.1
LACE1
lactation elevated 1
chr5_-_124080203 0.39 ENST00000504926.1
ZNF608
zinc finger protein 608
chr17_-_40833858 0.39 ENST00000332438.4
CCR10
chemokine (C-C motif) receptor 10
chr1_-_115124257 0.39 ENST00000369541.3
BCAS2
breast carcinoma amplified sequence 2
chr1_+_93544791 0.39 ENST00000545708.1
ENST00000540243.1
ENST00000370298.4
MTF2
metal response element binding transcription factor 2
chr4_+_66536248 0.39 ENST00000514260.1
ENST00000507117.1
RP11-807H7.1
RP11-807H7.1
chr2_+_61108650 0.38 ENST00000295025.8
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr17_-_7120498 0.38 ENST00000485100.1
DLG4
discs, large homolog 4 (Drosophila)
chr13_-_52027134 0.38 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr11_+_117947724 0.37 ENST00000534111.1
TMPRSS4
transmembrane protease, serine 4
chr9_+_131452239 0.37 ENST00000372688.4
ENST00000372686.5
SET
SET nuclear oncogene
chr11_+_19138670 0.36 ENST00000446113.2
ENST00000399351.3
ZDHHC13
zinc finger, DHHC-type containing 13
chr16_-_69418649 0.36 ENST00000566257.1
TERF2
telomeric repeat binding factor 2
chr12_-_95942563 0.36 ENST00000549639.1
ENST00000551837.1
USP44
ubiquitin specific peptidase 44
chr2_+_29033682 0.36 ENST00000379579.4
ENST00000334056.5
ENST00000449210.1
SPDYA
speedy/RINGO cell cycle regulator family member A
chr9_-_128003606 0.34 ENST00000324460.6
HSPA5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr1_+_27113963 0.34 ENST00000430292.1
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr3_-_49722523 0.34 ENST00000448220.1
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr3_+_38206975 0.33 ENST00000446845.1
ENST00000311806.3
OXSR1
oxidative stress responsive 1
chr18_-_45457192 0.33 ENST00000586514.1
ENST00000591214.1
ENST00000589877.1
SMAD2
SMAD family member 2
chr17_+_30771279 0.33 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr4_+_111397216 0.32 ENST00000265162.5
ENPEP
glutamyl aminopeptidase (aminopeptidase A)
chr12_-_122711968 0.32 ENST00000485724.1
DIABLO
diablo, IAP-binding mitochondrial protein
chr3_-_167452298 0.32 ENST00000475915.2
ENST00000462725.2
ENST00000461494.1
PDCD10
programmed cell death 10
chr3_-_167452262 0.32 ENST00000487947.2
PDCD10
programmed cell death 10
chrM_+_8527 0.32 ENST00000361899.2
MT-ATP6
mitochondrially encoded ATP synthase 6
chr9_+_17135016 0.32 ENST00000425824.1
ENST00000262360.5
ENST00000380641.4
CNTLN
centlein, centrosomal protein
chr17_+_57970469 0.32 ENST00000443572.2
ENST00000406116.3
ENST00000225577.4
ENST00000393021.3
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr11_-_125932685 0.32 ENST00000527967.1
CDON
cell adhesion associated, oncogene regulated
chr15_+_63481668 0.32 ENST00000321437.4
ENST00000559006.1
ENST00000448330.2
RAB8B
RAB8B, member RAS oncogene family
chr5_+_68788594 0.32 ENST00000396442.2
ENST00000380766.2
OCLN
occludin
chr20_+_43343517 0.32 ENST00000372865.4
WISP2
WNT1 inducible signaling pathway protein 2
chr2_-_61697862 0.31 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr21_-_27107198 0.31 ENST00000400094.1
ATP5J
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr6_-_84937314 0.31 ENST00000257766.4
ENST00000403245.3
KIAA1009
KIAA1009
chr1_+_199996702 0.31 ENST00000367362.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr15_+_89922345 0.30 ENST00000558982.1
LINC00925
long intergenic non-protein coding RNA 925
chr6_+_30908747 0.30 ENST00000462446.1
ENST00000304311.2
DPCR1
diffuse panbronchiolitis critical region 1
chr17_+_76311791 0.30 ENST00000586321.1
AC061992.2
AC061992.2
chr8_-_17270809 0.30 ENST00000180173.5
ENST00000521857.1
MTMR7
myotubularin related protein 7
chr6_-_130536774 0.29 ENST00000532763.1
SAMD3
sterile alpha motif domain containing 3
chr20_-_1165319 0.29 ENST00000429036.1
TMEM74B
transmembrane protein 74B
chr7_-_150675372 0.29 ENST00000262186.5
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr12_-_76462713 0.29 ENST00000552056.1
NAP1L1
nucleosome assembly protein 1-like 1
chr11_+_6260298 0.29 ENST00000379936.2
CNGA4
cyclic nucleotide gated channel alpha 4
chr20_-_44516256 0.29 ENST00000372519.3
SPATA25
spermatogenesis associated 25
chr12_+_95612006 0.29 ENST00000551311.1
ENST00000546445.1
VEZT
vezatin, adherens junctions transmembrane protein
chr1_-_28969517 0.29 ENST00000263974.4
ENST00000373824.4
TAF12
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
chr21_-_27107344 0.29 ENST00000457143.2
ATP5J
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr8_+_103563792 0.28 ENST00000285402.3
ODF1
outer dense fiber of sperm tails 1
chr9_-_37384431 0.28 ENST00000452923.1
RP11-397D12.4
RP11-397D12.4
chr1_-_113257905 0.28 ENST00000464951.1
PPM1J
protein phosphatase, Mg2+/Mn2+ dependent, 1J
chr13_+_76378357 0.28 ENST00000489941.2
ENST00000525373.1
LMO7
LIM domain 7
chr7_+_141438393 0.28 ENST00000484178.1
ENST00000473783.1
ENST00000481508.1
SSBP1
single-stranded DNA binding protein 1, mitochondrial
chr9_-_75567962 0.27 ENST00000297785.3
ENST00000376939.1
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr2_+_43864387 0.27 ENST00000282406.4
PLEKHH2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr1_+_26737292 0.27 ENST00000254231.4
LIN28A
lin-28 homolog A (C. elegans)
chr9_+_75766652 0.27 ENST00000257497.6
ANXA1
annexin A1
chr13_+_76378305 0.27 ENST00000526371.1
ENST00000526528.1
LMO7
LIM domain 7
chr12_-_123560608 0.27 ENST00000541244.1
PITPNM2
phosphatidylinositol transfer protein, membrane-associated 2
chr10_+_98592674 0.27 ENST00000356016.3
ENST00000371097.4
LCOR
ligand dependent nuclear receptor corepressor
chr19_-_44405941 0.27 ENST00000587128.1
RP11-15A1.3
RP11-15A1.3
chr20_+_44657845 0.27 ENST00000243964.3
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr15_-_33180439 0.27 ENST00000559610.1
FMN1
formin 1
chr2_-_160472952 0.27 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr14_-_55658323 0.27 ENST00000554067.1
ENST00000247191.2
DLGAP5
discs, large (Drosophila) homolog-associated protein 5
chr19_+_46002868 0.27 ENST00000396735.2
PPM1N
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr12_+_58148842 0.27 ENST00000266643.5
MARCH9
membrane-associated ring finger (C3HC4) 9
chr2_+_169312725 0.26 ENST00000392687.4
CERS6
ceramide synthase 6
chr17_-_7120525 0.26 ENST00000447163.1
ENST00000399506.2
ENST00000302955.6
DLG4
discs, large homolog 4 (Drosophila)
chr2_+_102758751 0.26 ENST00000442590.1
IL1R1
interleukin 1 receptor, type I
chr1_-_113258090 0.26 ENST00000309276.6
PPM1J
protein phosphatase, Mg2+/Mn2+ dependent, 1J
chr21_-_46962379 0.25 ENST00000311124.4
ENST00000380010.4
SLC19A1
solute carrier family 19 (folate transporter), member 1
chr17_+_57784997 0.25 ENST00000537567.1
ENST00000539763.1
ENST00000587945.1
ENST00000536180.1
ENST00000589823.2
ENST00000592106.1
ENST00000591315.1
ENST00000545362.1
VMP1
vacuole membrane protein 1
chr20_+_2517253 0.25 ENST00000358864.1
TMC2
transmembrane channel-like 2
chr14_-_98444386 0.25 ENST00000556462.1
ENST00000556138.1
C14orf64
chromosome 14 open reading frame 64
chr2_-_37544209 0.25 ENST00000234179.2
PRKD3
protein kinase D3
chr10_+_95256356 0.25 ENST00000371485.3
CEP55
centrosomal protein 55kDa
chr19_-_45748628 0.25 ENST00000590022.1
AC006126.4
AC006126.4
chr5_+_154320623 0.24 ENST00000523037.1
ENST00000265229.8
ENST00000439747.3
ENST00000522038.1
MRPL22
mitochondrial ribosomal protein L22
chr1_-_25256368 0.24 ENST00000308873.6
RUNX3
runt-related transcription factor 3
chr3_+_160117418 0.24 ENST00000465903.1
ENST00000485645.1
ENST00000360111.2
ENST00000472991.1
ENST00000467468.1
ENST00000469762.1
ENST00000489573.1
ENST00000462787.1
ENST00000490207.1
ENST00000485867.1
SMC4
structural maintenance of chromosomes 4
chrX_-_99891796 0.24 ENST00000373020.4
TSPAN6
tetraspanin 6
chr2_-_160473114 0.24 ENST00000392783.2
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr12_-_13529594 0.24 ENST00000539026.1
C12orf36
chromosome 12 open reading frame 36
chr1_+_199996733 0.24 ENST00000236914.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chrM_+_9207 0.24 ENST00000362079.2
MT-CO3
mitochondrially encoded cytochrome c oxidase III
chr9_-_73029540 0.24 ENST00000377126.2
KLF9
Kruppel-like factor 9
chr14_-_55658252 0.24 ENST00000395425.2
DLGAP5
discs, large (Drosophila) homolog-associated protein 5
chr1_+_8378140 0.23 ENST00000377479.2
SLC45A1
solute carrier family 45, member 1
chr10_-_105238997 0.23 ENST00000369783.4
CALHM3
calcium homeostasis modulator 3
chr14_+_45553296 0.23 ENST00000355765.6
ENST00000553605.1
PRPF39
pre-mRNA processing factor 39
chr17_-_39203519 0.23 ENST00000542137.1
ENST00000391419.3
KRTAP2-1
keratin associated protein 2-1
chr11_-_85430163 0.23 ENST00000529581.1
ENST00000533577.1
SYTL2
synaptotagmin-like 2
chr11_+_73358594 0.23 ENST00000227214.6
ENST00000398494.4
ENST00000543085.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chrX_+_123094672 0.23 ENST00000354548.5
ENST00000458700.1
STAG2
stromal antigen 2
chr8_+_22019168 0.23 ENST00000318561.3
ENST00000521315.1
ENST00000437090.2
ENST00000520605.1
ENST00000522109.1
ENST00000524255.1
ENST00000523296.1
ENST00000518615.1
SFTPC
surfactant protein C
chr19_-_51054299 0.23 ENST00000599957.1
LRRC4B
leucine rich repeat containing 4B
chr7_-_6523688 0.23 ENST00000490996.1
KDELR2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr10_-_74856608 0.23 ENST00000307116.2
ENST00000373008.2
ENST00000412021.2
ENST00000394890.2
ENST00000263556.3
ENST00000440381.1
P4HA1
prolyl 4-hydroxylase, alpha polypeptide I
chrX_+_123095155 0.23 ENST00000371160.1
ENST00000435103.1
STAG2
stromal antigen 2
chrX_+_21958814 0.23 ENST00000379404.1
ENST00000415881.2
SMS
spermine synthase
chr2_+_99953816 0.22 ENST00000289371.6
EIF5B
eukaryotic translation initiation factor 5B
chr5_+_56469843 0.22 ENST00000514387.2
GPBP1
GC-rich promoter binding protein 1
chr9_+_131451480 0.22 ENST00000322030.8
SET
SET nuclear oncogene
chr10_+_111765562 0.22 ENST00000360162.3
ADD3
adducin 3 (gamma)
chr11_+_111749942 0.22 ENST00000260276.3
C11orf1
chromosome 11 open reading frame 1
chr9_-_74979420 0.22 ENST00000343431.2
ENST00000376956.3
ZFAND5
zinc finger, AN1-type domain 5
chr8_-_124253576 0.22 ENST00000276704.4
C8orf76
chromosome 8 open reading frame 76
chr21_-_16374688 0.22 ENST00000411932.1
NRIP1
nuclear receptor interacting protein 1
chr2_+_172864490 0.22 ENST00000315796.4
METAP1D
methionyl aminopeptidase type 1D (mitochondrial)
chr7_-_99527243 0.22 ENST00000312891.2
GJC3
gap junction protein, gamma 3, 30.2kDa
chr2_+_61108771 0.22 ENST00000394479.3
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr7_+_27282319 0.22 ENST00000222761.3
EVX1
even-skipped homeobox 1

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX15_MGA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.5 1.6 GO:0042222 interleukin-1 biosynthetic process(GO:0042222) regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.5 1.5 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.4 2.1 GO:1902304 positive regulation of potassium ion export(GO:1902304)
0.3 1.6 GO:0010847 regulation of chromatin assembly(GO:0010847) protein auto-ADP-ribosylation(GO:0070213)
0.3 1.6 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.3 1.6 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.2 0.6 GO:0031247 actin rod assembly(GO:0031247)
0.2 0.8 GO:0032207 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.2 0.6 GO:0032826 natural killer cell differentiation involved in immune response(GO:0002325) regulation of natural killer cell differentiation involved in immune response(GO:0032826)
0.2 1.1 GO:0030421 defecation(GO:0030421)
0.2 0.9 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.2 0.5 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
0.2 1.1 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.6 GO:0036292 DNA rewinding(GO:0036292)
0.1 0.4 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.1 0.4 GO:0040040 thermosensory behavior(GO:0040040)
0.1 0.9 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.2 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.1 0.3 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.9 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.1 0.6 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.1 0.5 GO:2000329 peptidyl-lysine oxidation(GO:0018057) negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.1 0.3 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 0.4 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.4 GO:2001162 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.1 0.6 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.1 1.4 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 0.8 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.5 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.5 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 0.2 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 0.7 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.5 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 0.5 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 0.6 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.1 0.6 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.1 0.2 GO:2000987 cell communication by chemical coupling(GO:0010643) positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.1 0.9 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.6 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.3 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.1 0.3 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.1 0.7 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.2 GO:0043132 coenzyme A transport(GO:0015880) coenzyme A transmembrane transport(GO:0035349) NAD transport(GO:0043132) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.1 0.4 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.2 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.1 0.5 GO:0071287 cellular response to manganese ion(GO:0071287)
0.1 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.2 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.3 GO:0044254 angiotensin catabolic process in blood(GO:0002005) multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266)
0.1 0.2 GO:0061289 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.1 0.4 GO:1903288 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 1.7 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 1.6 GO:0010842 retina layer formation(GO:0010842)
0.0 0.4 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.0 0.2 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.5 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.2 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.2 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.1 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.0 0.1 GO:0021834 chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:1905069 allantois development(GO:1905069)
0.0 0.7 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.2 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:0060981 cell migration involved in coronary angiogenesis(GO:0060981)
0.0 0.2 GO:0051414 response to cortisol(GO:0051414)
0.0 0.3 GO:0072093 ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.0 1.1 GO:0044253 positive regulation of collagen metabolic process(GO:0010714) positive regulation of collagen biosynthetic process(GO:0032967) positive regulation of multicellular organismal metabolic process(GO:0044253)
0.0 0.9 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.7 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.2 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.3 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.5 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.2 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.4 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.1 GO:0046110 xanthine metabolic process(GO:0046110)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.5 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.2 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.1 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.0 GO:1904204 skeletal muscle hypertrophy(GO:0014734) regulation of skeletal muscle hypertrophy(GO:1904204)
0.0 3.5 GO:0007422 peripheral nervous system development(GO:0007422)
0.0 0.9 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.2 GO:0050955 thermoception(GO:0050955)
0.0 0.3 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.0 GO:0035284 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.3 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.2 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.1 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.0 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.2 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.6 GO:0016180 snRNA processing(GO:0016180)
0.0 0.1 GO:0032571 response to vitamin K(GO:0032571)
0.0 0.2 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.3 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.0 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.4 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.1 GO:1903433 regulation of constitutive secretory pathway(GO:1903433)
0.0 0.5 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.6 GO:0035067 negative regulation of histone acetylation(GO:0035067)
0.0 0.1 GO:0021633 optic nerve structural organization(GO:0021633)
0.0 1.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.2 GO:0070673 response to interleukin-18(GO:0070673)
0.0 0.3 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.2 GO:0050807 regulation of synapse organization(GO:0050807)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.3 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.1 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.2 GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532)
0.0 1.4 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.8 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.1 GO:0061087 regulation of histone H3-K27 methylation(GO:0061085) positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.1 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.1 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.1 GO:0032252 secretory granule localization(GO:0032252)
0.0 0.1 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.0 0.3 GO:0097264 self proteolysis(GO:0097264)
0.0 0.4 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.2 GO:0015884 folic acid transport(GO:0015884)
0.0 0.0 GO:0003273 cell migration involved in endocardial cushion formation(GO:0003273)
0.0 0.1 GO:0050821 protein stabilization(GO:0050821)
0.0 0.1 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.1 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.0 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 0.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.1 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.4 GO:0003016 respiratory system process(GO:0003016)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.8 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.1 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.1 GO:0045023 G0 to G1 transition(GO:0045023)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.6 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.1 0.9 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 1.0 GO:1990357 terminal web(GO:1990357)
0.1 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.5 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.4 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 1.7 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.1 0.6 GO:0031415 NatA complex(GO:0031415)
0.1 0.6 GO:0035976 AP1 complex(GO:0035976)
0.1 0.5 GO:0031501 mannosyltransferase complex(GO:0031501)
0.1 0.7 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 0.8 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.2 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) astrocyte end-foot(GO:0097450) glial limiting end-foot(GO:0097451)
0.1 0.2 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.4 GO:1902560 GMP reductase complex(GO:1902560)
0.1 0.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.2 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.1 2.0 GO:0042629 mast cell granule(GO:0042629)
0.0 0.4 GO:0032584 growth cone membrane(GO:0032584)
0.0 1.0 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.4 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.6 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0051286 cell tip(GO:0051286)
0.0 0.0 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.4 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 1.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.5 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.0 GO:0035101 FACT complex(GO:0035101)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.3 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.1 GO:0033010 paranodal junction(GO:0033010)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.2 GO:0000796 condensin complex(GO:0000796)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124) STAGA complex(GO:0030914)
0.0 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 1.1 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.3 GO:0090543 Flemming body(GO:0090543)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.5 GO:0000421 autophagosome membrane(GO:0000421)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.5 1.6 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.3 0.9 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.2 2.0 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.2 0.5 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.2 0.6 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.7 GO:0004966 galanin receptor activity(GO:0004966)
0.1 0.4 GO:0016768 spermine synthase activity(GO:0016768)
0.1 0.6 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 2.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.6 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.6 GO:0046790 virion binding(GO:0046790)
0.1 0.2 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.1 0.4 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.3 GO:0008518 reduced folate carrier activity(GO:0008518)
0.1 0.2 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 0.8 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 0.5 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 1.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.4 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 0.8 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.2 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.9 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 1.8 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.5 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.5 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.4 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.4 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 1.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.4 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0005046 KDEL sequence binding(GO:0005046)
0.0 0.1 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
0.0 0.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.3 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.9 GO:0034061 DNA polymerase activity(GO:0034061)
0.0 0.3 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.2 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.2 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.0 1.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.6 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 2.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.4 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.1 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.1 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 0.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.0 GO:0071633 dihydroceramidase activity(GO:0071633)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.2 GO:0036122 BMP binding(GO:0036122)
0.0 0.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.2 GO:0005542 folic acid binding(GO:0005542)
0.0 0.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.1 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.0 0.0 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936) coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.5 GO:0005521 lamin binding(GO:0005521)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 1.5 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.2 GO:0016594 glycine binding(GO:0016594)
0.0 0.9 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.0 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 3.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.9 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.1 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.1 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 1.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.2 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.9 PID ATM PATHWAY ATM pathway
0.0 0.6 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.7 PID AURORA B PATHWAY Aurora B signaling
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.1 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 3.1 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 1.0 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 2.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 2.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.8 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 1.1 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.4 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.8 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.4 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.1 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0 0.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly