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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TCF21

Z-value: 0.97

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Transcription factors associated with TCF21

Gene Symbol Gene ID Gene Info
TCF21
ENSG00000118526.6 transcription factor 21

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TCF21hg19_v2_chr6_+_134210243_1342102760.286.0e-01Click!

Activity profile of TCF21 motif

Sorted Z-values of TCF21 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_615570 2.09 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
IRF7
interferon regulatory factor 7
chr1_+_79115503 1.51 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44
interferon-induced protein 44
chr11_-_615942 1.23 ENST00000397562.3
ENST00000330243.5
ENST00000397570.1
ENST00000397574.2
IRF7
interferon regulatory factor 7
chr11_+_117103333 0.83 ENST00000534428.1
RNF214
ring finger protein 214
chr2_+_231280954 0.79 ENST00000409824.1
ENST00000409341.1
ENST00000409112.1
ENST00000340126.4
ENST00000341950.4
SP100
SP100 nuclear antigen
chr2_+_231280908 0.71 ENST00000427101.2
ENST00000432979.1
SP100
SP100 nuclear antigen
chr1_+_92414952 0.56 ENST00000449584.1
ENST00000427104.1
ENST00000355011.3
ENST00000448194.1
ENST00000426141.1
ENST00000450792.1
ENST00000548992.1
ENST00000552654.1
ENST00000457265.1
BRDT
bromodomain, testis-specific
chr3_+_167453493 0.53 ENST00000295777.5
ENST00000472747.2
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr6_-_41673552 0.48 ENST00000419574.1
ENST00000445214.1
TFEB
transcription factor EB
chr2_-_7005785 0.46 ENST00000256722.5
ENST00000404168.1
ENST00000458098.1
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr13_+_41635617 0.42 ENST00000542082.1
WBP4
WW domain binding protein 4
chr1_+_172422026 0.41 ENST00000367725.4
C1orf105
chromosome 1 open reading frame 105
chr17_+_71228793 0.40 ENST00000426147.2
C17orf80
chromosome 17 open reading frame 80
chr17_+_71229346 0.40 ENST00000535032.2
ENST00000582793.1
C17orf80
chromosome 17 open reading frame 80
chr8_-_99837856 0.40 ENST00000518165.1
ENST00000419617.2
STK3
serine/threonine kinase 3
chr17_-_62499334 0.39 ENST00000579996.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr11_+_117103441 0.37 ENST00000531287.1
ENST00000531452.1
RNF214
ring finger protein 214
chr10_+_52499682 0.37 ENST00000185907.9
ENST00000374006.1
ASAH2B
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2B
chr22_-_22863466 0.37 ENST00000406426.1
ENST00000360412.2
ZNF280B
zinc finger protein 280B
chr20_-_23402028 0.37 ENST00000398425.3
ENST00000432543.2
ENST00000377026.4
NAPB
N-ethylmaleimide-sensitive factor attachment protein, beta
chrM_+_7586 0.37 ENST00000361739.1
MT-CO2
mitochondrially encoded cytochrome c oxidase II
chr2_+_149402009 0.37 ENST00000457184.1
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr2_+_86116396 0.36 ENST00000455121.3
AC105053.4
AC105053.4
chr8_-_71519889 0.36 ENST00000521425.1
TRAM1
translocation associated membrane protein 1
chr19_-_33716750 0.34 ENST00000253188.4
SLC7A10
solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10
chr2_+_44001172 0.34 ENST00000260605.8
ENST00000406852.3
ENST00000443170.3
ENST00000398823.2
ENST00000605786.1
DYNC2LI1
dynein, cytoplasmic 2, light intermediate chain 1
chr12_-_50677255 0.33 ENST00000551691.1
ENST00000394943.3
ENST00000341247.4
LIMA1
LIM domain and actin binding 1
chr13_-_20767037 0.33 ENST00000382848.4
GJB2
gap junction protein, beta 2, 26kDa
chr10_-_105238997 0.32 ENST00000369783.4
CALHM3
calcium homeostasis modulator 3
chr2_-_17981462 0.31 ENST00000402989.1
ENST00000428868.1
SMC6
structural maintenance of chromosomes 6
chr3_-_81792780 0.31 ENST00000489715.1
GBE1
glucan (1,4-alpha-), branching enzyme 1
chr11_+_74862100 0.31 ENST00000532236.1
ENST00000531756.1
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chr2_+_38177575 0.31 ENST00000407257.1
ENST00000417700.2
ENST00000234195.3
ENST00000442857.1
RMDN2
regulator of microtubule dynamics 2
chr9_-_123812542 0.31 ENST00000223642.1
C5
complement component 5
chr17_+_68165657 0.31 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr11_-_10920714 0.30 ENST00000533941.1
CTD-2003C8.2
CTD-2003C8.2
chr17_-_7193711 0.30 ENST00000571464.1
YBX2
Y box binding protein 2
chr3_+_167453026 0.29 ENST00000472941.1
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr17_+_11924129 0.29 ENST00000353533.5
ENST00000415385.3
MAP2K4
mitogen-activated protein kinase kinase 4
chr17_+_71228740 0.29 ENST00000268942.8
ENST00000359042.2
C17orf80
chromosome 17 open reading frame 80
chr20_-_52790055 0.29 ENST00000395955.3
CYP24A1
cytochrome P450, family 24, subfamily A, polypeptide 1
chr15_+_65337708 0.29 ENST00000334287.2
SLC51B
solute carrier family 51, beta subunit
chr21_+_37692481 0.27 ENST00000400485.1
MORC3
MORC family CW-type zinc finger 3
chr11_-_10920838 0.27 ENST00000503469.2
CTD-2003C8.2
CTD-2003C8.2
chrX_+_17755696 0.27 ENST00000419185.1
SCML1
sex comb on midleg-like 1 (Drosophila)
chr5_+_170288856 0.26 ENST00000523189.1
RANBP17
RAN binding protein 17
chr17_+_34848049 0.26 ENST00000588902.1
ENST00000591067.1
ZNHIT3
zinc finger, HIT-type containing 3
chr1_-_63782888 0.26 ENST00000436475.2
LINC00466
long intergenic non-protein coding RNA 466
chr19_+_1452188 0.25 ENST00000587149.1
APC2
adenomatosis polyposis coli 2
chr18_+_3247779 0.25 ENST00000578611.1
ENST00000583449.1
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr9_-_3469181 0.25 ENST00000366116.2
AL365202.1
Uncharacterized protein
chr5_-_102455801 0.24 ENST00000508629.1
ENST00000399004.2
GIN1
gypsy retrotransposon integrase 1
chr1_-_150669604 0.24 ENST00000427665.1
ENST00000540514.1
GOLPH3L
golgi phosphoprotein 3-like
chr18_+_158513 0.24 ENST00000400266.3
ENST00000580410.1
ENST00000383589.2
ENST00000261601.7
USP14
ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
chr11_+_74862032 0.24 ENST00000289575.5
ENST00000341411.4
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chr15_+_63796779 0.23 ENST00000561442.1
ENST00000560070.1
ENST00000540797.1
ENST00000380324.3
ENST00000268049.7
ENST00000536001.1
ENST00000539772.1
USP3
ubiquitin specific peptidase 3
chr12_+_104458235 0.23 ENST00000229330.4
HCFC2
host cell factor C2
chr2_-_122494487 0.23 ENST00000451734.1
ENST00000285814.4
MKI67IP
nucleolar protein interacting with the FHA domain of MKI67
chr10_+_94594351 0.23 ENST00000371552.4
EXOC6
exocyst complex component 6
chr8_+_33342268 0.22 ENST00000360128.6
MAK16
MAK16 homolog (S. cerevisiae)
chr9_+_6758109 0.22 ENST00000536108.1
KDM4C
lysine (K)-specific demethylase 4C
chr17_+_38083977 0.22 ENST00000578802.1
ENST00000578478.1
ENST00000582263.1
RP11-387H17.4
RP11-387H17.4
chr6_-_30080876 0.21 ENST00000376734.3
TRIM31
tripartite motif containing 31
chr21_+_30673091 0.21 ENST00000447177.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr11_+_74862140 0.21 ENST00000525650.1
ENST00000454962.2
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chr3_+_169684553 0.21 ENST00000337002.4
ENST00000480708.1
SEC62
SEC62 homolog (S. cerevisiae)
chr17_-_191188 0.21 ENST00000575634.1
RPH3AL
rabphilin 3A-like (without C2 domains)
chr10_-_7661623 0.20 ENST00000298441.6
ITIH5
inter-alpha-trypsin inhibitor heavy chain family, member 5
chr2_+_171627597 0.20 ENST00000429172.1
ENST00000426475.1
AC007405.6
AC007405.6
chr12_+_56473628 0.20 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr14_-_53258180 0.20 ENST00000554230.1
GNPNAT1
glucosamine-phosphate N-acetyltransferase 1
chr13_-_50510434 0.19 ENST00000361840.3
SPRYD7
SPRY domain containing 7
chr13_-_50510622 0.19 ENST00000378195.2
SPRYD7
SPRY domain containing 7
chr3_+_122296465 0.19 ENST00000483793.1
PARP15
poly (ADP-ribose) polymerase family, member 15
chr8_-_82633476 0.19 ENST00000518419.1
ENST00000517588.1
ENST00000521895.1
ENST00000520076.1
ENST00000519523.1
ENST00000522520.1
ENST00000521287.1
ENST00000523096.1
ENST00000220669.5
ENST00000517450.1
ZFAND1
zinc finger, AN1-type domain 1
chr1_-_114429997 0.19 ENST00000471267.1
ENST00000393320.3
BCL2L15
BCL2-like 15
chr3_-_176915215 0.19 ENST00000457928.2
ENST00000422442.1
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr11_-_14913765 0.19 ENST00000334636.5
CYP2R1
cytochrome P450, family 2, subfamily R, polypeptide 1
chr14_-_23288930 0.19 ENST00000554517.1
ENST00000285850.7
ENST00000397529.2
ENST00000555702.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr17_+_39421591 0.19 ENST00000391355.1
KRTAP9-6
keratin associated protein 9-6
chr9_+_6758024 0.19 ENST00000442236.2
KDM4C
lysine (K)-specific demethylase 4C
chr14_-_50154921 0.19 ENST00000553805.2
ENST00000554396.1
ENST00000216367.5
ENST00000539565.2
POLE2
polymerase (DNA directed), epsilon 2, accessory subunit
chr1_+_78354297 0.18 ENST00000334785.7
NEXN
nexilin (F actin binding protein)
chr3_+_179065474 0.18 ENST00000471841.1
ENST00000280653.7
MFN1
mitofusin 1
chr8_-_19540266 0.18 ENST00000311540.4
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr8_-_55014415 0.18 ENST00000522007.1
ENST00000521898.1
ENST00000518546.1
ENST00000316963.3
LYPLA1
lysophospholipase I
chr1_-_150849208 0.18 ENST00000358595.5
ARNT
aryl hydrocarbon receptor nuclear translocator
chr17_-_39183452 0.18 ENST00000361883.5
KRTAP1-5
keratin associated protein 1-5
chr20_-_1165319 0.18 ENST00000429036.1
TMEM74B
transmembrane protein 74B
chr2_+_113321939 0.18 ENST00000458012.2
POLR1B
polymerase (RNA) I polypeptide B, 128kDa
chr3_+_183948161 0.18 ENST00000426955.2
VWA5B2
von Willebrand factor A domain containing 5B2
chr15_+_57998821 0.18 ENST00000299638.3
POLR2M
polymerase (RNA) II (DNA directed) polypeptide M
chr15_-_99548775 0.18 ENST00000378919.6
PGPEP1L
pyroglutamyl-peptidase I-like
chr12_+_72233487 0.18 ENST00000482439.2
ENST00000550746.1
ENST00000491063.1
ENST00000319106.8
ENST00000485960.2
ENST00000393309.3
TBC1D15
TBC1 domain family, member 15
chr6_+_31554962 0.18 ENST00000376092.3
ENST00000376086.3
ENST00000303757.8
ENST00000376093.2
ENST00000376102.3
LST1
leukocyte specific transcript 1
chr6_+_44355257 0.17 ENST00000371477.3
CDC5L
cell division cycle 5-like
chrX_-_108868390 0.17 ENST00000372101.2
KCNE1L
KCNE1-like
chr8_-_19540086 0.17 ENST00000332246.6
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr2_+_33701707 0.17 ENST00000425210.1
ENST00000444784.1
ENST00000423159.1
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr1_-_6550625 0.17 ENST00000377725.1
ENST00000340850.5
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr2_+_192110199 0.17 ENST00000304164.4
MYO1B
myosin IB
chr5_+_68513557 0.17 ENST00000256441.4
MRPS36
mitochondrial ribosomal protein S36
chr11_-_64512469 0.17 ENST00000377485.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr15_+_57998923 0.17 ENST00000380557.4
POLR2M
polymerase (RNA) II (DNA directed) polypeptide M
chr10_-_51130715 0.17 ENST00000402038.3
PARG
poly (ADP-ribose) glycohydrolase
chr5_-_58571935 0.16 ENST00000503258.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr3_-_182833863 0.16 ENST00000492597.1
MCCC1
methylcrotonoyl-CoA carboxylase 1 (alpha)
chr15_+_89787180 0.16 ENST00000300027.8
ENST00000310775.7
ENST00000567891.1
ENST00000564920.1
ENST00000565255.1
ENST00000567996.1
ENST00000451393.2
ENST00000563250.1
FANCI
Fanconi anemia, complementation group I
chr16_+_55522536 0.16 ENST00000570283.1
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr12_-_52845910 0.16 ENST00000252252.3
KRT6B
keratin 6B
chr12_-_68845417 0.16 ENST00000542875.1
RP11-81H14.2
RP11-81H14.2
chr17_+_4487294 0.16 ENST00000338859.4
SMTNL2
smoothelin-like 2
chr14_+_31091511 0.16 ENST00000544052.2
ENST00000421551.3
ENST00000541123.1
ENST00000557076.1
ENST00000553693.1
ENST00000396629.2
SCFD1
sec1 family domain containing 1
chr4_+_95972822 0.16 ENST00000509540.1
ENST00000440890.2
BMPR1B
bone morphogenetic protein receptor, type IB
chr12_+_50355647 0.16 ENST00000293599.6
AQP5
aquaporin 5
chr9_-_100954910 0.16 ENST00000375077.4
CORO2A
coronin, actin binding protein, 2A
chr12_+_16500599 0.16 ENST00000535309.1
ENST00000540056.1
ENST00000396209.1
ENST00000540126.1
MGST1
microsomal glutathione S-transferase 1
chr16_-_9030515 0.15 ENST00000535863.1
ENST00000381886.4
USP7
ubiquitin specific peptidase 7 (herpes virus-associated)
chr17_-_7081435 0.15 ENST00000380920.4
ASGR1
asialoglycoprotein receptor 1
chr1_-_39339777 0.15 ENST00000397572.2
MYCBP
MYC binding protein
chr2_-_158345341 0.15 ENST00000435117.1
CYTIP
cytohesin 1 interacting protein
chr2_+_68384976 0.15 ENST00000263657.2
PNO1
partner of NOB1 homolog (S. cerevisiae)
chr6_-_13711773 0.14 ENST00000011619.3
RANBP9
RAN binding protein 9
chr6_+_143772060 0.14 ENST00000367591.4
PEX3
peroxisomal biogenesis factor 3
chr12_+_16500571 0.14 ENST00000543076.1
ENST00000396210.3
MGST1
microsomal glutathione S-transferase 1
chr6_-_27835357 0.14 ENST00000331442.3
HIST1H1B
histone cluster 1, H1b
chr5_-_142784101 0.14 ENST00000503201.1
ENST00000502892.1
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr10_+_17686221 0.14 ENST00000540523.1
STAM
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr10_-_12084770 0.14 ENST00000357604.5
UPF2
UPF2 regulator of nonsense transcripts homolog (yeast)
chr19_-_45826125 0.14 ENST00000221476.3
CKM
creatine kinase, muscle
chr2_-_190627481 0.14 ENST00000264151.5
ENST00000520350.1
ENST00000521630.1
ENST00000517895.1
OSGEPL1
O-sialoglycoprotein endopeptidase-like 1
chr20_-_23030296 0.14 ENST00000377103.2
THBD
thrombomodulin
chr7_+_99102573 0.14 ENST00000394170.2
ZKSCAN5
zinc finger with KRAB and SCAN domains 5
chr9_-_130541017 0.14 ENST00000314830.8
SH2D3C
SH2 domain containing 3C
chr14_+_69658194 0.14 ENST00000409018.3
ENST00000409014.1
ENST00000409675.1
EXD2
exonuclease 3'-5' domain containing 2
chr8_-_30013748 0.13 ENST00000607315.1
RP11-51J9.5
RP11-51J9.5
chr7_+_87563557 0.13 ENST00000439864.1
ENST00000412441.1
ENST00000398201.4
ENST00000265727.7
ENST00000315984.7
ENST00000398209.3
ADAM22
ADAM metallopeptidase domain 22
chr5_+_49962772 0.13 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr12_+_8850471 0.13 ENST00000535829.1
ENST00000357529.3
RIMKLB
ribosomal modification protein rimK-like family member B
chr3_-_10332416 0.13 ENST00000450603.1
ENST00000449554.2
GHRL
ghrelin/obestatin prepropeptide
chr4_-_89152474 0.13 ENST00000515655.1
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr13_+_37574678 0.13 ENST00000389704.3
EXOSC8
exosome component 8
chr6_-_31648150 0.13 ENST00000375858.3
ENST00000383237.4
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr3_+_145782358 0.13 ENST00000422482.1
AC107021.1
HCG1786590; PRO2533; Uncharacterized protein
chr6_+_116832789 0.13 ENST00000368599.3
FAM26E
family with sequence similarity 26, member E
chr2_-_224702270 0.13 ENST00000396654.2
ENST00000396653.2
ENST00000423110.1
ENST00000443700.1
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr19_-_50400212 0.13 ENST00000391826.2
IL4I1
interleukin 4 induced 1
chr2_+_33701286 0.13 ENST00000403687.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chrX_-_16887963 0.13 ENST00000380084.4
RBBP7
retinoblastoma binding protein 7
chr20_-_1165117 0.13 ENST00000381894.3
TMEM74B
transmembrane protein 74B
chr10_-_46641003 0.13 ENST00000395721.2
ENST00000374218.2
ENST00000395725.3
ENST00000374346.3
ENST00000417004.1
PTPN20A
protein tyrosine phosphatase, non-receptor type 20A
chr12_-_105352080 0.13 ENST00000433540.1
SLC41A2
solute carrier family 41 (magnesium transporter), member 2
chr4_-_123843597 0.13 ENST00000510735.1
ENST00000304430.5
NUDT6
nudix (nucleoside diphosphate linked moiety X)-type motif 6
chr2_-_191115229 0.12 ENST00000409820.2
ENST00000410045.1
HIBCH
3-hydroxyisobutyryl-CoA hydrolase
chr12_+_9142131 0.12 ENST00000356986.3
ENST00000266551.4
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr7_+_66205712 0.12 ENST00000451741.2
ENST00000442563.1
ENST00000450873.2
ENST00000284957.5
KCTD7
RABGEF1
potassium channel tetramerization domain containing 7
RAB guanine nucleotide exchange factor (GEF) 1
chr14_-_45431091 0.12 ENST00000579157.1
ENST00000396128.4
ENST00000556500.1
KLHL28
kelch-like family member 28
chr8_-_123706338 0.12 ENST00000521608.1
RP11-973F15.1
long intergenic non-protein coding RNA 1151
chr9_+_6757634 0.12 ENST00000543771.1
ENST00000401787.3
ENST00000381306.3
ENST00000381309.3
KDM4C
lysine (K)-specific demethylase 4C
chr1_+_25757376 0.12 ENST00000399766.3
ENST00000399763.3
ENST00000374343.4
TMEM57
transmembrane protein 57
chr3_-_54962100 0.12 ENST00000273286.5
LRTM1
leucine-rich repeats and transmembrane domains 1
chr11_-_88070920 0.12 ENST00000524463.1
ENST00000227266.5
CTSC
cathepsin C
chr2_+_234602305 0.12 ENST00000406651.1
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr11_-_82997420 0.12 ENST00000455220.2
ENST00000529689.1
CCDC90B
coiled-coil domain containing 90B
chr3_+_197677379 0.12 ENST00000442341.1
RPL35A
ribosomal protein L35a
chr12_+_14572070 0.12 ENST00000545769.1
ENST00000428217.2
ENST00000396279.2
ENST00000542514.1
ENST00000536279.1
ATF7IP
activating transcription factor 7 interacting protein
chr16_+_5009250 0.12 ENST00000587469.1
SEC14L5
SEC14-like 5 (S. cerevisiae)
chr14_+_58666824 0.12 ENST00000254286.4
ACTR10
actin-related protein 10 homolog (S. cerevisiae)
chr10_+_60094735 0.11 ENST00000373910.4
UBE2D1
ubiquitin-conjugating enzyme E2D 1
chr16_-_832926 0.11 ENST00000293892.3
MSLNL
mesothelin-like
chr6_-_72130472 0.11 ENST00000426635.2
LINC00472
long intergenic non-protein coding RNA 472
chr4_+_186347388 0.11 ENST00000511138.1
ENST00000511581.1
C4orf47
chromosome 4 open reading frame 47
chr21_-_38362497 0.11 ENST00000427746.1
ENST00000336648.4
HLCS
holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
chr8_+_38089198 0.11 ENST00000528358.1
ENST00000529642.1
ENST00000532222.1
ENST00000520272.2
DDHD2
DDHD domain containing 2
chr3_+_49059038 0.11 ENST00000451378.2
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr6_+_150070857 0.11 ENST00000544496.1
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr15_+_75487984 0.11 ENST00000563905.1
C15orf39
chromosome 15 open reading frame 39
chr11_+_125496619 0.11 ENST00000532669.1
ENST00000278916.3
CHEK1
checkpoint kinase 1
chr17_+_19314505 0.11 ENST00000461366.1
RNF112
ring finger protein 112
chr19_-_4559814 0.11 ENST00000586582.1
SEMA6B
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr5_-_98262240 0.11 ENST00000284049.3
CHD1
chromodomain helicase DNA binding protein 1
chr17_-_26989136 0.11 ENST00000247020.4
SDF2
stromal cell-derived factor 2
chr7_+_12726623 0.10 ENST00000439721.1
ARL4A
ADP-ribosylation factor-like 4A
chrX_+_9880412 0.10 ENST00000418909.2
SHROOM2
shroom family member 2
chr6_+_150070831 0.10 ENST00000367380.5
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr7_-_25164868 0.10 ENST00000409409.1
ENST00000409764.1
ENST00000413447.1
CYCS
cytochrome c, somatic
chr3_+_113666748 0.10 ENST00000330212.3
ENST00000498275.1
ZDHHC23
zinc finger, DHHC-type containing 23
chr16_-_3422283 0.10 ENST00000399974.3
MTRNR2L4
MT-RNR2-like 4
chr19_+_57999101 0.10 ENST00000347466.6
ENST00000523138.1
ENST00000415379.2
ENST00000521754.1
ENST00000221735.7
ENST00000518999.1
ENST00000521137.1
ZNF419
zinc finger protein 419
chr6_+_31555045 0.10 ENST00000396101.3
ENST00000490742.1
LST1
leukocyte specific transcript 1
chr14_+_67999999 0.10 ENST00000329153.5
PLEKHH1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr4_-_140223670 0.10 ENST00000394228.1
ENST00000539387.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr3_+_49058444 0.10 ENST00000326925.6
ENST00000395458.2
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr7_-_48068643 0.10 ENST00000453192.2
SUN3
Sad1 and UNC84 domain containing 3
chr7_-_132766800 0.10 ENST00000542753.1
ENST00000448878.1
CHCHD3
coiled-coil-helix-coiled-coil-helix domain containing 3
chr5_+_130506629 0.10 ENST00000510516.1
ENST00000507584.1
LYRM7
LYR motif containing 7
chr1_-_150849174 0.10 ENST00000515192.1
ARNT
aryl hydrocarbon receptor nuclear translocator
chr6_+_17102489 0.09 ENST00000536551.1
STMND1
stathmin domain containing 1
chr22_-_50964558 0.09 ENST00000535425.1
ENST00000439934.1
SCO2
SCO2 cytochrome c oxidase assembly protein
chr11_-_31531121 0.09 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF21

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.2 1.5 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.2 0.6 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.1 0.5 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.1 0.3 GO:0051685 maintenance of ER location(GO:0051685)
0.1 0.3 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.3 GO:0009386 translational attenuation(GO:0009386)
0.1 0.4 GO:0044752 response to human chorionic gonadotropin(GO:0044752)
0.1 0.3 GO:0042369 vitamin D catabolic process(GO:0042369)
0.1 0.3 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.1 0.4 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.3 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 0.3 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.1 0.3 GO:2000672 cellular response to sorbitol(GO:0072709) negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.3 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.1 GO:0008057 eye pigment granule organization(GO:0008057)
0.0 0.5 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.2 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.1 GO:1904344 positive regulation of growth rate(GO:0040010) regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) gastric mucosal blood circulation(GO:1990768)
0.0 0.4 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.2 GO:1990637 response to prolactin(GO:1990637)
0.0 0.3 GO:0042940 D-amino acid transport(GO:0042940)
0.0 0.1 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.0 0.4 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.1 GO:0038109 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0 0.2 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.1 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.0 GO:0098904 regulation of AV node cell action potential(GO:0098904)
0.0 0.2 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.2 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.1 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.0 0.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.3 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.2 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.3 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.0 0.3 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.0 0.4 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0097195 pilomotor reflex(GO:0097195)
0.0 0.1 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.2 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.0 0.3 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.2 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.1 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.0 0.3 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.1 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.0 GO:1900195 positive regulation of oocyte maturation(GO:1900195)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.0 0.4 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0009726 detection of endogenous stimulus(GO:0009726)
0.0 0.1 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.0 0.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.0 0.1 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.0 0.0 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.0 0.1 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.0 GO:0033967 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.2 GO:0060613 fat pad development(GO:0060613)
0.0 0.3 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0048749 compound eye development(GO:0048749)
0.0 0.2 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.1 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.0 0.0 GO:0070295 renal water absorption(GO:0070295)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.0 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.1 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.1 GO:0045047 protein targeting to ER(GO:0045047)
0.0 0.0 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.1 GO:0035932 mineralocorticoid secretion(GO:0035931) aldosterone secretion(GO:0035932) regulation of mineralocorticoid secretion(GO:2000855) positive regulation of mineralocorticoid secretion(GO:2000857) regulation of aldosterone secretion(GO:2000858) positive regulation of aldosterone secretion(GO:2000860)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.3 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.3 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.2 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.1 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.3 GO:0097449 astrocyte projection(GO:0097449)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.0 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.0 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.5 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.0 GO:0005602 complement component C1 complex(GO:0005602)
0.0 0.2 GO:0070938 contractile ring(GO:0070938)
0.0 0.3 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:0034678 smooth muscle contractile fiber(GO:0030485) integrin alpha8-beta1 complex(GO:0034678)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.5 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 0.3 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 0.4 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.2 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.1 0.3 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.1 0.3 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1 0.4 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 0.1 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.1 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.0 0.1 GO:0016608 growth hormone-releasing hormone activity(GO:0016608) ghrelin receptor binding(GO:0031768)
0.0 0.2 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.4 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.1 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.0 0.1 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.8 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.0 0.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 3.2 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.2 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.3 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.3 GO:0043295 glutathione binding(GO:0043295)
0.0 0.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.0 GO:0036009 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.0 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.1 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.0 GO:0047860 diiodophenylpyruvate reductase activity(GO:0047860)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.0 GO:0090541 MIT domain binding(GO:0090541)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.9 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.8 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.1 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling