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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TFAP2B

Z-value: 0.97

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Transcription factors associated with TFAP2B

Gene Symbol Gene ID Gene Info
TFAP2B
ENSG00000008196.8 transcription factor AP-2 beta

Activity profile of TFAP2B motif

Sorted Z-values of TFAP2B motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_108424738 0.62 ENST00000334077.3
TAL2
T-cell acute lymphocytic leukemia 2
chr7_-_100065686 0.52 ENST00000423266.1
ENST00000456330.1
TSC22D4
TSC22 domain family, member 4
chr17_+_47448102 0.52 ENST00000576461.1
RP11-81K2.1
Uncharacterized protein
chr2_+_232575168 0.52 ENST00000440384.1
PTMA
prothymosin, alpha
chr19_-_18717627 0.47 ENST00000392386.3
CRLF1
cytokine receptor-like factor 1
chr9_-_34523027 0.39 ENST00000399775.2
ENHO
energy homeostasis associated
chr4_+_8271471 0.37 ENST00000307358.2
ENST00000382512.3
HTRA3
HtrA serine peptidase 3
chr11_+_73000449 0.36 ENST00000535931.1
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr19_+_50338234 0.35 ENST00000593767.1
MED25
mediator complex subunit 25
chr17_+_27052892 0.33 ENST00000579671.1
ENST00000579060.1
NEK8
NIMA-related kinase 8
chr11_+_63974135 0.33 ENST00000544997.1
ENST00000345728.5
ENST00000279227.5
FERMT3
fermitin family member 3
chr11_+_62379194 0.33 ENST00000525801.1
ENST00000534093.1
ROM1
retinal outer segment membrane protein 1
chr15_+_23810853 0.33 ENST00000568252.1
MKRN3
makorin ring finger protein 3
chr17_-_17399701 0.30 ENST00000225688.3
ENST00000579152.1
RASD1
RAS, dexamethasone-induced 1
chrX_-_154033686 0.30 ENST00000453245.1
ENST00000428488.1
ENST00000369531.1
MPP1
membrane protein, palmitoylated 1, 55kDa
chr1_+_46269248 0.29 ENST00000361297.2
ENST00000372009.2
MAST2
microtubule associated serine/threonine kinase 2
chr2_+_74741569 0.29 ENST00000233638.7
TLX2
T-cell leukemia homeobox 2
chr6_+_30294186 0.29 ENST00000458516.1
TRIM39
tripartite motif containing 39
chr7_-_86849836 0.28 ENST00000455575.1
TMEM243
transmembrane protein 243, mitochondrial
chr1_-_21948906 0.28 ENST00000374761.2
ENST00000599760.1
RAP1GAP
RAP1 GTPase activating protein
chrX_+_53449805 0.28 ENST00000414955.2
RIBC1
RIB43A domain with coiled-coils 1
chr6_+_43139037 0.28 ENST00000265354.4
SRF
serum response factor (c-fos serum response element-binding transcription factor)
chr1_+_160370344 0.27 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr12_-_89746264 0.27 ENST00000548755.1
DUSP6
dual specificity phosphatase 6
chr13_-_107187462 0.27 ENST00000245323.4
EFNB2
ephrin-B2
chr19_-_42724261 0.25 ENST00000595337.1
DEDD2
death effector domain containing 2
chr5_+_148521046 0.25 ENST00000326685.7
ENST00000356541.3
ENST00000309868.7
ABLIM3
actin binding LIM protein family, member 3
chr5_+_177540444 0.25 ENST00000274605.5
N4BP3
NEDD4 binding protein 3
chr19_+_10541462 0.25 ENST00000293683.5
PDE4A
phosphodiesterase 4A, cAMP-specific
chr4_+_1723197 0.25 ENST00000485989.2
ENST00000313288.4
TACC3
transforming, acidic coiled-coil containing protein 3
chr16_+_24857309 0.25 ENST00000565769.1
ENST00000449109.2
ENST00000424767.2
ENST00000545376.1
ENST00000569520.1
SLC5A11
solute carrier family 5 (sodium/inositol cotransporter), member 11
chr3_+_158450143 0.24 ENST00000491804.1
MFSD1
major facilitator superfamily domain containing 1
chr19_+_1354930 0.24 ENST00000591337.1
MUM1
melanoma associated antigen (mutated) 1
chr11_-_64660916 0.24 ENST00000413053.1
MIR194-2
microRNA 194-2
chr17_+_36508826 0.24 ENST00000580660.1
SOCS7
suppressor of cytokine signaling 7
chr16_-_88772761 0.24 ENST00000567844.1
ENST00000312838.4
RNF166
ring finger protein 166
chr9_-_131534188 0.23 ENST00000414921.1
ZER1
zyg-11 related, cell cycle regulator
chr17_-_17726907 0.23 ENST00000423161.3
SREBF1
sterol regulatory element binding transcription factor 1
chr6_-_35888858 0.23 ENST00000507909.1
SRPK1
SRSF protein kinase 1
chr17_+_12692774 0.23 ENST00000379672.5
ENST00000340825.3
ARHGAP44
Rho GTPase activating protein 44
chr6_-_34664612 0.23 ENST00000374023.3
ENST00000374026.3
C6orf106
chromosome 6 open reading frame 106
chr1_+_154377669 0.22 ENST00000368485.3
ENST00000344086.4
IL6R
interleukin 6 receptor
chr19_+_38397839 0.22 ENST00000222345.6
SIPA1L3
signal-induced proliferation-associated 1 like 3
chr10_-_135238076 0.22 ENST00000414069.2
SPRN
shadow of prion protein homolog (zebrafish)
chr16_+_57126428 0.22 ENST00000290776.8
CPNE2
copine II
chr20_+_44746939 0.22 ENST00000372276.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr4_-_190948409 0.22 ENST00000504750.1
ENST00000378763.1
FRG2
FSHD region gene 2
chrX_+_53449887 0.22 ENST00000375327.3
RIBC1
RIB43A domain with coiled-coils 1
chr22_+_31199037 0.22 ENST00000424224.1
OSBP2
oxysterol binding protein 2
chr22_-_39639021 0.22 ENST00000455790.1
PDGFB
platelet-derived growth factor beta polypeptide
chr17_-_8093471 0.22 ENST00000389017.4
C17orf59
chromosome 17 open reading frame 59
chr17_-_48133054 0.21 ENST00000499842.1
RP11-1094H24.4
RP11-1094H24.4
chr16_+_24857552 0.21 ENST00000568579.1
ENST00000567758.1
ENST00000569071.1
ENST00000539472.1
SLC5A11
solute carrier family 5 (sodium/inositol cotransporter), member 11
chr19_-_1650666 0.21 ENST00000588136.1
TCF3
transcription factor 3
chr2_-_135476552 0.21 ENST00000281924.6
TMEM163
transmembrane protein 163
chr11_+_64002292 0.21 ENST00000426086.2
VEGFB
vascular endothelial growth factor B
chr5_-_176730733 0.21 ENST00000504395.1
RAB24
RAB24, member RAS oncogene family
chr11_+_64001962 0.21 ENST00000309422.2
VEGFB
vascular endothelial growth factor B
chr17_+_79953310 0.21 ENST00000582355.2
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr16_-_31085514 0.21 ENST00000300849.4
ZNF668
zinc finger protein 668
chr12_+_53693466 0.20 ENST00000267103.5
ENST00000548632.1
C12orf10
chromosome 12 open reading frame 10
chrX_+_53449839 0.20 ENST00000457095.1
RIBC1
RIB43A domain with coiled-coils 1
chr12_+_49212261 0.20 ENST00000547818.1
ENST00000547392.1
CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr1_-_1677358 0.20 ENST00000355439.2
ENST00000400924.1
ENST00000246421.4
SLC35E2
solute carrier family 35, member E2
chr20_+_60174827 0.20 ENST00000543233.1
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr8_-_143867946 0.20 ENST00000301263.4
LY6D
lymphocyte antigen 6 complex, locus D
chr14_+_23340822 0.20 ENST00000359591.4
LRP10
low density lipoprotein receptor-related protein 10
chr19_+_19144384 0.20 ENST00000392335.2
ENST00000535612.1
ENST00000537263.1
ENST00000540707.1
ENST00000541725.1
ENST00000269932.6
ENST00000546344.1
ENST00000540792.1
ENST00000536098.1
ENST00000541898.1
ENST00000543877.1
ARMC6
armadillo repeat containing 6
chr12_+_110011571 0.19 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
MVK
mevalonate kinase
chr17_+_12693001 0.19 ENST00000262444.9
ARHGAP44
Rho GTPase activating protein 44
chr3_-_183145765 0.19 ENST00000473233.1
MCF2L2
MCF.2 cell line derived transforming sequence-like 2
chr1_+_155006300 0.19 ENST00000295542.1
ENST00000392480.1
ENST00000423025.2
ENST00000368419.2
DCST1
DC-STAMP domain containing 1
chr19_-_19144243 0.19 ENST00000594445.1
ENST00000452918.2
ENST00000600377.1
ENST00000337018.6
SUGP2
SURP and G patch domain containing 2
chr1_+_45792541 0.19 ENST00000334815.3
HPDL
4-hydroxyphenylpyruvate dioxygenase-like
chr16_+_30907927 0.19 ENST00000279804.2
ENST00000395019.3
CTF1
cardiotrophin 1
chr5_-_176981417 0.19 ENST00000514747.1
ENST00000443375.2
ENST00000329540.5
FAM193B
family with sequence similarity 193, member B
chr19_+_14544099 0.19 ENST00000242783.6
ENST00000586557.1
ENST00000590097.1
PKN1
protein kinase N1
chr9_+_116917807 0.19 ENST00000356083.3
COL27A1
collagen, type XXVII, alpha 1
chr19_-_19774473 0.18 ENST00000357324.6
ATP13A1
ATPase type 13A1
chr2_-_220408430 0.18 ENST00000243776.6
CHPF
chondroitin polymerizing factor
chr6_+_43112037 0.18 ENST00000473339.1
PTK7
protein tyrosine kinase 7
chr1_-_156399184 0.18 ENST00000368243.1
ENST00000357975.4
ENST00000310027.5
ENST00000400991.2
C1orf61
chromosome 1 open reading frame 61
chr3_-_10052849 0.18 ENST00000437616.1
ENST00000429065.2
AC022007.5
AC022007.5
chr8_+_22462532 0.18 ENST00000389279.3
CCAR2
cell cycle and apoptosis regulator 2
chr7_-_27213893 0.18 ENST00000283921.4
HOXA10
homeobox A10
chr19_-_39832563 0.18 ENST00000599274.1
CTC-246B18.10
CTC-246B18.10
chr19_+_13229126 0.18 ENST00000292431.4
NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr12_+_6493406 0.18 ENST00000543190.1
LTBR
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr20_-_49639631 0.17 ENST00000424171.1
ENST00000439216.1
ENST00000371571.4
KCNG1
potassium voltage-gated channel, subfamily G, member 1
chr17_-_41856305 0.17 ENST00000397937.2
ENST00000226004.3
DUSP3
dual specificity phosphatase 3
chr21_+_44394742 0.17 ENST00000432907.2
PKNOX1
PBX/knotted 1 homeobox 1
chr6_+_33378738 0.17 ENST00000374512.3
ENST00000374516.3
PHF1
PHD finger protein 1
chr2_-_128408105 0.17 ENST00000409254.1
LIMS2
LIM and senescent cell antigen-like domains 2
chr22_+_50781723 0.17 ENST00000359139.3
ENST00000395741.3
ENST00000395744.3
PPP6R2
protein phosphatase 6, regulatory subunit 2
chr3_+_138068051 0.17 ENST00000474559.1
MRAS
muscle RAS oncogene homolog
chr17_+_4901199 0.17 ENST00000320785.5
ENST00000574165.1
KIF1C
kinesin family member 1C
chr8_+_22462145 0.17 ENST00000308511.4
ENST00000523801.1
ENST00000521301.1
CCAR2
cell cycle and apoptosis regulator 2
chr16_+_57126482 0.17 ENST00000537605.1
ENST00000535318.2
CPNE2
copine II
chr16_-_66959429 0.17 ENST00000420652.1
ENST00000299759.6
RRAD
Ras-related associated with diabetes
chr7_-_150864635 0.17 ENST00000297537.4
GBX1
gastrulation brain homeobox 1
chr14_+_65171099 0.17 ENST00000247226.7
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr6_-_30654977 0.17 ENST00000399199.3
PPP1R18
protein phosphatase 1, regulatory subunit 18
chr17_-_72869086 0.16 ENST00000581530.1
ENST00000420580.2
ENST00000455107.2
ENST00000413947.2
ENST00000581219.1
ENST00000582944.1
FDXR
ferredoxin reductase
chr12_+_49212514 0.16 ENST00000301050.2
ENST00000548279.1
ENST00000547230.1
CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr17_-_72869140 0.16 ENST00000583917.1
ENST00000293195.5
ENST00000442102.2
FDXR
ferredoxin reductase
chr16_+_88772866 0.16 ENST00000453996.2
ENST00000312060.5
ENST00000378384.3
ENST00000567949.1
ENST00000564921.1
CTU2
cytosolic thiouridylase subunit 2 homolog (S. pombe)
chr17_-_4463856 0.16 ENST00000574584.1
ENST00000381550.3
ENST00000301395.3
GGT6
gamma-glutamyltransferase 6
chr22_-_51017084 0.16 ENST00000360719.2
ENST00000457250.1
ENST00000440709.1
CPT1B
carnitine palmitoyltransferase 1B (muscle)
chr16_+_67465016 0.16 ENST00000326152.5
HSD11B2
hydroxysteroid (11-beta) dehydrogenase 2
chr2_-_191399073 0.16 ENST00000421038.1
TMEM194B
transmembrane protein 194B
chr11_+_10326612 0.16 ENST00000534464.1
ENST00000530439.1
ENST00000524948.1
ENST00000528655.1
ENST00000526492.1
ENST00000525063.1
ADM
adrenomedullin
chr1_-_44497118 0.16 ENST00000537678.1
ENST00000466926.1
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr19_-_37329254 0.16 ENST00000356725.4
ZNF790
zinc finger protein 790
chr5_+_148521136 0.16 ENST00000506113.1
ABLIM3
actin binding LIM protein family, member 3
chr16_-_67970990 0.16 ENST00000358514.4
PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr8_+_21906433 0.16 ENST00000522148.1
DMTN
dematin actin binding protein
chr1_-_25291475 0.16 ENST00000338888.3
ENST00000399916.1
RUNX3
runt-related transcription factor 3
chr14_+_65171315 0.16 ENST00000394691.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr17_+_1627834 0.16 ENST00000419248.1
ENST00000418841.1
WDR81
WD repeat domain 81
chr14_-_94254821 0.16 ENST00000393140.1
PRIMA1
proline rich membrane anchor 1
chr12_-_123380610 0.16 ENST00000535765.1
VPS37B
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr19_+_42724423 0.16 ENST00000301215.3
ENST00000597945.1
ZNF526
zinc finger protein 526
chr16_+_30960375 0.16 ENST00000318663.4
ENST00000566237.1
ENST00000562699.1
ORAI3
ORAI calcium release-activated calcium modulator 3
chr5_+_148521381 0.16 ENST00000504238.1
ABLIM3
actin binding LIM protein family, member 3
chr15_+_85144217 0.16 ENST00000540936.1
ENST00000448803.2
ENST00000546275.1
ENST00000546148.1
ENST00000442073.3
ENST00000334141.3
ENST00000358472.3
ENST00000502939.2
ENST00000379358.3
ENST00000327179.6
ZSCAN2
zinc finger and SCAN domain containing 2
chr12_+_6493319 0.15 ENST00000536876.1
LTBR
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr5_-_176730676 0.15 ENST00000393611.2
ENST00000303251.6
ENST00000303270.6
RAB24
RAB24, member RAS oncogene family
chr5_+_149737202 0.15 ENST00000451292.1
ENST00000377797.3
ENST00000445265.2
ENST00000323668.7
ENST00000439160.2
ENST00000394269.3
ENST00000427724.2
ENST00000504761.2
ENST00000513346.1
ENST00000515516.1
TCOF1
Treacher Collins-Franceschetti syndrome 1
chr17_+_4613918 0.15 ENST00000574954.1
ENST00000346341.2
ENST00000572457.1
ENST00000381488.6
ENST00000412477.3
ENST00000571428.1
ENST00000575877.1
ARRB2
arrestin, beta 2
chr1_+_221054584 0.15 ENST00000549319.1
HLX
H2.0-like homeobox
chr5_-_157002775 0.15 ENST00000257527.4
ADAM19
ADAM metallopeptidase domain 19
chr21_+_17566643 0.15 ENST00000419952.1
ENST00000445461.2
LINC00478
long intergenic non-protein coding RNA 478
chr9_-_131534160 0.15 ENST00000291900.2
ZER1
zyg-11 related, cell cycle regulator
chr5_+_149980622 0.15 ENST00000394243.1
SYNPO
synaptopodin
chr11_+_65082289 0.15 ENST00000279249.2
CDC42EP2
CDC42 effector protein (Rho GTPase binding) 2
chr22_-_29663690 0.15 ENST00000406335.1
RHBDD3
rhomboid domain containing 3
chr19_-_16738984 0.15 ENST00000600060.1
ENST00000263390.3
MED26
mediator complex subunit 26
chr8_+_38758845 0.15 ENST00000519640.1
PLEKHA2
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
chr17_-_78450398 0.15 ENST00000306773.4
NPTX1
neuronal pentraxin I
chr7_-_25219667 0.15 ENST00000444434.1
C7orf31
chromosome 7 open reading frame 31
chr11_+_117198545 0.14 ENST00000533153.1
ENST00000278935.3
ENST00000525416.1
CEP164
centrosomal protein 164kDa
chr20_-_44937124 0.14 ENST00000537909.1
CDH22
cadherin 22, type 2
chr16_+_30772913 0.14 ENST00000563909.1
RNF40
ring finger protein 40, E3 ubiquitin protein ligase
chr14_+_102786063 0.14 ENST00000442396.2
ENST00000262236.5
ZNF839
zinc finger protein 839
chr22_-_36424458 0.14 ENST00000438146.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr19_+_37742773 0.14 ENST00000438770.2
ENST00000591116.1
ENST00000592712.1
AC012309.5
AC012309.5
chr1_+_221054411 0.14 ENST00000427693.1
HLX
H2.0-like homeobox
chr3_+_75713481 0.14 ENST00000308062.3
ENST00000464571.1
FRG2C
FSHD region gene 2 family, member C
chr3_+_39424828 0.14 ENST00000273158.4
ENST00000431510.1
SLC25A38
solute carrier family 25, member 38
chr17_+_46985823 0.14 ENST00000508468.2
UBE2Z
ubiquitin-conjugating enzyme E2Z
chr5_+_172068232 0.14 ENST00000520919.1
ENST00000522853.1
ENST00000369800.5
NEURL1B
neuralized E3 ubiquitin protein ligase 1B
chr19_+_42387228 0.14 ENST00000354532.3
ENST00000599846.1
ENST00000347545.4
ARHGEF1
Rho guanine nucleotide exchange factor (GEF) 1
chr1_-_11741155 0.14 ENST00000445656.1
ENST00000376669.5
ENST00000456915.1
ENST00000376692.4
MAD2L2
MAD2 mitotic arrest deficient-like 2 (yeast)
chr20_-_56285595 0.14 ENST00000395816.3
ENST00000347215.4
PMEPA1
prostate transmembrane protein, androgen induced 1
chr3_-_50360165 0.14 ENST00000428028.1
HYAL2
hyaluronoglucosaminidase 2
chr14_+_24458123 0.14 ENST00000545240.1
ENST00000382755.4
DHRS4L2
dehydrogenase/reductase (SDR family) member 4 like 2
chr19_+_7459998 0.14 ENST00000319670.9
ENST00000599752.1
ARHGEF18
Rho/Rac guanine nucleotide exchange factor (GEF) 18
chr17_-_36906058 0.14 ENST00000580830.1
PCGF2
polycomb group ring finger 2
chr1_-_23886285 0.14 ENST00000374561.5
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr6_-_31763276 0.14 ENST00000440048.1
VARS
valyl-tRNA synthetase
chr22_-_31742218 0.14 ENST00000266269.5
ENST00000405309.3
ENST00000351933.4
PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr16_-_30381580 0.14 ENST00000409939.3
TBC1D10B
TBC1 domain family, member 10B
chr17_-_42767092 0.14 ENST00000588687.1
CCDC43
coiled-coil domain containing 43
chr17_-_73874654 0.14 ENST00000254816.2
TRIM47
tripartite motif containing 47
chr14_+_23341513 0.14 ENST00000546834.1
LRP10
low density lipoprotein receptor-related protein 10
chr1_+_9299895 0.14 ENST00000602477.1
H6PD
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr2_-_43453734 0.13 ENST00000282388.3
ZFP36L2
ZFP36 ring finger protein-like 2
chr8_-_8751068 0.13 ENST00000276282.6
MFHAS1
malignant fibrous histiocytoma amplified sequence 1
chr17_+_36858694 0.13 ENST00000563897.1
CTB-58E17.1
CTB-58E17.1
chr8_-_145018905 0.13 ENST00000398774.2
PLEC
plectin
chr5_+_148521454 0.13 ENST00000508983.1
ABLIM3
actin binding LIM protein family, member 3
chr10_+_103825080 0.13 ENST00000299238.5
HPS6
Hermansky-Pudlak syndrome 6
chr16_-_28503080 0.13 ENST00000565316.1
ENST00000565778.1
ENST00000357857.9
ENST00000568558.1
ENST00000357806.7
CLN3
ceroid-lipofuscinosis, neuronal 3
chr1_+_26437631 0.13 ENST00000444713.1
PDIK1L
PDLIM1 interacting kinase 1 like
chr1_-_40782938 0.13 ENST00000372736.3
ENST00000372748.3
COL9A2
collagen, type IX, alpha 2
chr18_-_21242833 0.13 ENST00000586087.1
ENST00000592179.1
ANKRD29
ankyrin repeat domain 29
chr13_+_52158610 0.13 ENST00000298125.5
WDFY2
WD repeat and FYVE domain containing 2
chr22_+_31892373 0.13 ENST00000443011.1
ENST00000400289.1
ENST00000444859.1
ENST00000400288.2
SFI1
Sfi1 homolog, spindle assembly associated (yeast)
chr20_+_44746885 0.13 ENST00000372285.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr5_+_176730769 0.13 ENST00000303204.4
ENST00000503216.1
PRELID1
PRELI domain containing 1
chr6_+_33378517 0.13 ENST00000428274.1
PHF1
PHD finger protein 1
chr5_+_141016969 0.13 ENST00000518856.1
RELL2
RELT-like 2
chr4_-_2010562 0.13 ENST00000411649.1
ENST00000542778.1
ENST00000411638.2
ENST00000431323.1
NELFA
negative elongation factor complex member A
chr8_-_21988558 0.13 ENST00000312841.8
HR
hair growth associated
chr1_+_156084461 0.13 ENST00000347559.2
ENST00000361308.4
ENST00000368300.4
ENST00000368299.3
LMNA
lamin A/C
chr22_-_38484922 0.13 ENST00000428572.1
BAIAP2L2
BAI1-associated protein 2-like 2
chr7_+_101460882 0.13 ENST00000292535.7
ENST00000549414.2
ENST00000550008.2
ENST00000546411.2
ENST00000556210.1
CUX1
cut-like homeobox 1
chr11_-_6502534 0.13 ENST00000254584.2
ENST00000525235.1
ENST00000445086.2
ARFIP2
ADP-ribosylation factor interacting protein 2
chr7_+_75932863 0.13 ENST00000429938.1
HSPB1
heat shock 27kDa protein 1
chr14_+_102430855 0.13 ENST00000360184.4
DYNC1H1
dynein, cytoplasmic 1, heavy chain 1
chr17_+_18163848 0.13 ENST00000323019.4
ENST00000578174.1
ENST00000395704.4
ENST00000395703.4
ENST00000578621.1
ENST00000579341.1
MIEF2
mitochondrial elongation factor 2
chr10_+_104154229 0.13 ENST00000428099.1
ENST00000369966.3
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr16_+_2255841 0.12 ENST00000301725.7
MLST8
MTOR associated protein, LST8 homolog (S. cerevisiae)
chr12_-_52585765 0.12 ENST00000313234.5
ENST00000394815.2
KRT80
keratin 80
chr15_+_96873921 0.12 ENST00000394166.3
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr8_-_144655141 0.12 ENST00000398882.3
MROH6
maestro heat-like repeat family member 6
chr22_-_46933067 0.12 ENST00000262738.3
ENST00000395964.1
CELSR1
cadherin, EGF LAG seven-pass G-type receptor 1
chr8_+_142138711 0.12 ENST00000518347.1
ENST00000262585.2
ENST00000424248.1
ENST00000519811.1
ENST00000520986.1
ENST00000523058.1
DENND3
DENN/MADD domain containing 3
chr1_+_11994715 0.12 ENST00000449038.1
ENST00000376369.3
ENST00000429000.2
ENST00000196061.4
PLOD1
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
chr2_-_132249955 0.12 ENST00000309451.6
MZT2A
mitotic spindle organizing protein 2A

Network of associatons between targets according to the STRING database.

First level regulatory network of TFAP2B

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 0.6 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.5 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.3 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.1 0.3 GO:0060532 bronchus cartilage development(GO:0060532) lung smooth muscle development(GO:0061145)
0.1 0.3 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 0.3 GO:2001178 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.1 0.2 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.1 0.5 GO:0015798 myo-inositol transport(GO:0015798)
0.1 0.2 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.3 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 0.2 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.1 0.5 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.2 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.2 GO:0090677 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.1 0.2 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.6 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.3 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.4 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.1 GO:0019732 antifungal humoral response(GO:0019732)
0.0 0.3 GO:0033590 response to cobalamin(GO:0033590) response to erythropoietin(GO:0036017) cellular response to erythropoietin(GO:0036018)
0.0 0.3 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.3 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.2 GO:0072312 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.0 0.2 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.0 0.1 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.2 GO:0019087 transformation of host cell by virus(GO:0019087) renal water absorption(GO:0070295)
0.0 0.7 GO:0021794 thalamus development(GO:0021794)
0.0 0.2 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.2 GO:0019230 proprioception(GO:0019230)
0.0 0.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.1 GO:0071879 UDP-glucose catabolic process(GO:0006258) positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.0 0.1 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.1 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.1 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.2 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.2 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.3 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.1 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.3 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.1 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.1 GO:0003335 corneocyte development(GO:0003335)
0.0 0.4 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.1 GO:0034059 response to anoxia(GO:0034059)
0.0 0.2 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.2 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.2 GO:0002326 B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.2 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.1 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.0 0.2 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.0 0.1 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.2 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.4 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.2 GO:0035634 response to stilbenoid(GO:0035634)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.4 GO:1901978 positive regulation of cell cycle checkpoint(GO:1901978)
0.0 0.4 GO:0035330 regulation of hippo signaling(GO:0035330)
0.0 0.1 GO:1901911 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.1 GO:0014734 skeletal muscle hypertrophy(GO:0014734) regulation of skeletal muscle hypertrophy(GO:1904204)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.1 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.3 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.1 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 0.1 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.0 GO:0035106 operant conditioning(GO:0035106)
0.0 0.1 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.3 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.2 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.0 GO:0070384 Harderian gland development(GO:0070384)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.1 GO:0039019 pronephric nephron development(GO:0039019)
0.0 0.0 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.0 GO:0035283 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.2 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.1 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.0 0.4 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.0 0.2 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.1 GO:2001166 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.1 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.0 GO:0010716 negative regulation of extracellular matrix disassembly(GO:0010716)
0.0 0.1 GO:0070141 response to UV-A(GO:0070141)
0.0 0.0 GO:2000630 positive regulation of miRNA metabolic process(GO:2000630)
0.0 0.1 GO:0060313 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.0 0.0 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205)
0.0 0.0 GO:0007418 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938) notochord regression(GO:0060032)
0.0 0.1 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.0 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.0 0.0 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.1 GO:0015816 glycine transport(GO:0015816)
0.0 0.1 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.1 GO:0044856 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.0 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535) regulation of positive thymic T cell selection(GO:1902232)
0.0 0.1 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.0 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.1 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.1 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.3 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.2 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0044609 DBIRD complex(GO:0044609)
0.1 0.3 GO:0097543 ciliary inversin compartment(GO:0097543)
0.1 0.5 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 0.3 GO:0060187 cell pole(GO:0060187)
0.1 0.2 GO:0005608 laminin-3 complex(GO:0005608)
0.0 0.1 GO:0097444 spine apparatus(GO:0097444)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.4 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.2 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0019867 outer membrane(GO:0019867)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.3 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0004324 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.1 0.3 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.4 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.2 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 0.3 GO:0010736 serum response element binding(GO:0010736)
0.1 0.3 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.2 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.5 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.5 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.2 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.0 0.1 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981) ciliary neurotrophic factor binding(GO:0070119)
0.0 0.2 GO:0033906 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.0 0.1 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.0 0.2 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.0 0.4 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.1 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.1 GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.0 0.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.6 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.3 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822) inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.1 GO:0052848 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.1 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.2 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.2 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.8 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.6 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.0 GO:0004803 transposase activity(GO:0004803)
0.0 0.0 GO:0038131 neuregulin receptor activity(GO:0038131)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.8 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.4 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling