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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TFAP4_MSC

Z-value: 1.12

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Transcription factors associated with TFAP4_MSC

Gene Symbol Gene ID Gene Info
TFAP4
ENSG00000090447.7 transcription factor AP-4
MSC
ENSG00000178860.8 musculin

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFAP4hg19_v2_chr16_-_4323015_4323076-0.305.6e-01Click!
MSChg19_v2_chr8_-_72756667_727567360.305.7e-01Click!

Activity profile of TFAP4_MSC motif

Sorted Z-values of TFAP4_MSC motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_68845417 1.39 ENST00000542875.1
RP11-81H14.2
RP11-81H14.2
chr2_+_33701684 1.00 ENST00000442390.1
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr2_-_42160486 0.94 ENST00000427054.1
AC104654.2
AC104654.2
chr15_-_40401062 0.69 ENST00000354670.4
ENST00000559701.1
ENST00000557870.1
ENST00000558774.1
BMF
Bcl2 modifying factor
chr16_-_21289627 0.68 ENST00000396023.2
ENST00000415987.2
CRYM
crystallin, mu
chr8_-_123706338 0.55 ENST00000521608.1
RP11-973F15.1
long intergenic non-protein coding RNA 1151
chr14_-_91282821 0.47 ENST00000553948.1
TTC7B
tetratricopeptide repeat domain 7B
chr2_+_233404429 0.47 ENST00000389494.3
ENST00000389492.3
CHRNG
cholinergic receptor, nicotinic, gamma (muscle)
chr3_-_178790057 0.46 ENST00000311417.2
ZMAT3
zinc finger, matrin-type 3
chr3_-_178789220 0.45 ENST00000414084.1
ZMAT3
zinc finger, matrin-type 3
chr14_+_104710541 0.45 ENST00000419115.1
C14orf144
chromosome 14 open reading frame 144
chr10_+_1102303 0.43 ENST00000381329.1
WDR37
WD repeat domain 37
chr8_-_95961578 0.42 ENST00000448464.2
ENST00000342697.4
TP53INP1
tumor protein p53 inducible nuclear protein 1
chr5_+_148960931 0.41 ENST00000333677.6
ARHGEF37
Rho guanine nucleotide exchange factor (GEF) 37
chr2_+_33701707 0.40 ENST00000425210.1
ENST00000444784.1
ENST00000423159.1
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr15_+_75487984 0.37 ENST00000563905.1
C15orf39
chromosome 15 open reading frame 39
chrX_-_30326445 0.36 ENST00000378963.1
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr20_+_33292507 0.33 ENST00000414082.1
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr12_+_57828521 0.32 ENST00000309668.2
INHBC
inhibin, beta C
chr20_+_34679725 0.32 ENST00000432589.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr10_+_80027105 0.32 ENST00000461034.1
ENST00000476909.1
ENST00000459633.1
LINC00595
long intergenic non-protein coding RNA 595
chr3_-_52869205 0.31 ENST00000446157.2
MUSTN1
musculoskeletal, embryonic nuclear protein 1
chr12_+_69201923 0.31 ENST00000462284.1
ENST00000258149.5
ENST00000356290.4
ENST00000540827.1
ENST00000428863.2
ENST00000393412.3
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
chr16_-_31105870 0.31 ENST00000394971.3
VKORC1
vitamin K epoxide reductase complex, subunit 1
chr4_-_153303658 0.30 ENST00000296555.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr9_+_102584128 0.29 ENST00000338488.4
ENST00000395097.2
NR4A3
nuclear receptor subfamily 4, group A, member 3
chr4_+_37892682 0.29 ENST00000508802.1
ENST00000261439.4
ENST00000402522.1
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr8_+_87111059 0.28 ENST00000285393.3
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr3_+_69134124 0.28 ENST00000478935.1
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr1_+_153600869 0.27 ENST00000292169.1
ENST00000368696.3
ENST00000436839.1
S100A1
S100 calcium binding protein A1
chr8_-_145016692 0.27 ENST00000357649.2
PLEC
plectin
chr17_+_7461849 0.27 ENST00000338784.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr17_-_27467418 0.26 ENST00000528564.1
MYO18A
myosin XVIIIA
chr1_+_203256898 0.25 ENST00000433008.1
RP11-134P9.3
RP11-134P9.3
chr5_-_173173171 0.25 ENST00000517733.1
ENST00000518902.1
CTB-43E15.3
CTB-43E15.3
chr12_-_86650077 0.25 ENST00000552808.2
ENST00000547225.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr1_+_212738676 0.25 ENST00000366981.4
ENST00000366987.2
ATF3
activating transcription factor 3
chr2_+_95537248 0.24 ENST00000427593.2
TEKT4
tektin 4
chr11_+_33061336 0.24 ENST00000602733.1
TCP11L1
t-complex 11, testis-specific-like 1
chr17_+_45286387 0.24 ENST00000572316.1
ENST00000354968.1
ENST00000576874.1
ENST00000536623.2
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr1_-_206945830 0.24 ENST00000423557.1
IL10
interleukin 10
chr8_+_9413410 0.23 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr2_-_73460334 0.23 ENST00000258083.2
PRADC1
protease-associated domain containing 1
chr16_+_2570340 0.23 ENST00000568263.1
ENST00000293971.6
ENST00000302956.4
ENST00000413459.3
ENST00000566706.1
ENST00000569879.1
AMDHD2
amidohydrolase domain containing 2
chr20_-_39317868 0.22 ENST00000373313.2
MAFB
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr3_-_52486841 0.22 ENST00000496590.1
TNNC1
troponin C type 1 (slow)
chr15_-_67439270 0.22 ENST00000558463.1
RP11-342M21.2
Uncharacterized protein
chr1_+_178482262 0.22 ENST00000367641.3
ENST00000367639.1
TEX35
testis expressed 35
chr21_+_17791648 0.22 ENST00000602892.1
ENST00000418813.2
ENST00000435697.1
LINC00478
long intergenic non-protein coding RNA 478
chr2_+_11752379 0.22 ENST00000396123.1
GREB1
growth regulation by estrogen in breast cancer 1
chr17_+_65040678 0.21 ENST00000226021.3
CACNG1
calcium channel, voltage-dependent, gamma subunit 1
chr17_+_76037081 0.21 ENST00000588549.1
TNRC6C
trinucleotide repeat containing 6C
chr15_-_52944231 0.21 ENST00000546305.2
FAM214A
family with sequence similarity 214, member A
chr19_+_36249044 0.20 ENST00000444637.2
ENST00000396908.4
ENST00000544099.1
C19orf55
chromosome 19 open reading frame 55
chr20_-_31124186 0.20 ENST00000375678.3
C20orf112
chromosome 20 open reading frame 112
chr19_-_56663250 0.20 ENST00000376271.1
AC024580.1
Uncharacterized protein
chr12_-_133464118 0.19 ENST00000540963.1
CHFR
checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
chr2_+_177001685 0.19 ENST00000432796.2
HOXD3
homeobox D3
chr22_-_37882395 0.19 ENST00000416983.3
ENST00000424765.2
ENST00000356998.3
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr8_-_42396185 0.18 ENST00000518717.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr4_-_164534657 0.18 ENST00000339875.5
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr8_-_144679264 0.18 ENST00000531953.1
ENST00000526133.1
EEF1D
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr2_+_37311588 0.18 ENST00000409774.1
ENST00000608836.1
GPATCH11
G patch domain containing 11
chr6_-_133055815 0.18 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
VNN3
vanin 3
chr1_-_161168834 0.18 ENST00000367995.3
ENST00000367996.5
ADAMTS4
ADAM metallopeptidase with thrombospondin type 1 motif, 4
chr2_-_179914760 0.18 ENST00000420890.2
ENST00000409284.1
ENST00000443758.1
ENST00000446116.1
CCDC141
coiled-coil domain containing 141
chr4_+_39408470 0.18 ENST00000257408.4
KLB
klotho beta
chr2_+_27505260 0.18 ENST00000380075.2
ENST00000296098.4
TRIM54
tripartite motif containing 54
chr7_+_134832808 0.18 ENST00000275767.3
TMEM140
transmembrane protein 140
chrY_+_14774265 0.18 ENST00000457658.1
ENST00000440408.1
ENST00000543097.1
TTTY15
testis-specific transcript, Y-linked 15 (non-protein coding)
chr1_-_9129735 0.17 ENST00000377424.4
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chrX_+_15756382 0.17 ENST00000318636.3
CA5B
carbonic anhydrase VB, mitochondrial
chr12_-_70093111 0.17 ENST00000548658.1
ENST00000476098.1
ENST00000331471.4
ENST00000393365.1
BEST3
bestrophin 3
chr12_-_54121212 0.17 ENST00000548263.1
ENST00000430117.2
ENST00000550804.1
ENST00000549173.1
ENST00000551900.1
ENST00000546619.1
ENST00000548177.1
ENST00000549349.1
CALCOCO1
calcium binding and coiled-coil domain 1
chr17_+_34901353 0.17 ENST00000593016.1
GGNBP2
gametogenetin binding protein 2
chr15_+_49715293 0.17 ENST00000267843.4
ENST00000560270.1
FGF7
fibroblast growth factor 7
chr17_+_39346139 0.17 ENST00000398470.1
ENST00000318329.5
KRTAP9-1
keratin associated protein 9-1
chr4_+_48492269 0.17 ENST00000327939.4
ZAR1
zygote arrest 1
chr3_-_52860850 0.17 ENST00000441637.2
ITIH4
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr14_-_73493784 0.17 ENST00000553891.1
ZFYVE1
zinc finger, FYVE domain containing 1
chr17_-_41132010 0.16 ENST00000409103.1
ENST00000360221.4
PTGES3L-AARSD1
PTGES3L-AARSD1 readthrough
chr15_+_67547113 0.16 ENST00000512104.1
ENST00000358767.3
ENST00000546225.1
IQCH
IQ motif containing H
chr1_+_14075903 0.16 ENST00000343137.4
ENST00000503842.1
ENST00000407521.3
ENST00000505823.1
PRDM2
PR domain containing 2, with ZNF domain
chr11_-_62457371 0.16 ENST00000317449.4
LRRN4CL
LRRN4 C-terminal like
chr15_+_41186637 0.16 ENST00000558474.1
VPS18
vacuolar protein sorting 18 homolog (S. cerevisiae)
chr21_+_17791838 0.16 ENST00000453910.1
LINC00478
long intergenic non-protein coding RNA 478
chr2_+_37311645 0.16 ENST00000281932.5
GPATCH11
G patch domain containing 11
chr20_-_56195449 0.16 ENST00000541799.1
ZBP1
Z-DNA binding protein 1
chr11_-_117747327 0.16 ENST00000584230.1
ENST00000527429.1
ENST00000584394.1
ENST00000532984.1
FXYD6
FXYD6-FXYD2
FXYD domain containing ion transport regulator 6
FXYD6-FXYD2 readthrough
chr2_-_225811747 0.16 ENST00000409592.3
DOCK10
dedicator of cytokinesis 10
chr12_-_76879852 0.16 ENST00000548341.1
OSBPL8
oxysterol binding protein-like 8
chr2_-_42180940 0.16 ENST00000378711.2
C2orf91
chromosome 2 open reading frame 91
chr12_-_56122426 0.16 ENST00000551173.1
CD63
CD63 molecule
chr6_+_41021027 0.15 ENST00000244669.2
APOBEC2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
chr4_-_15661474 0.15 ENST00000509314.1
ENST00000503196.1
FBXL5
F-box and leucine-rich repeat protein 5
chr7_+_48128854 0.15 ENST00000436673.1
ENST00000429491.2
UPP1
uridine phosphorylase 1
chr16_+_12059091 0.15 ENST00000562385.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr4_+_159727272 0.15 ENST00000379346.3
FNIP2
folliculin interacting protein 2
chr6_-_133055896 0.15 ENST00000367927.5
ENST00000425515.2
ENST00000207771.3
ENST00000392393.3
ENST00000450865.2
ENST00000392394.2
VNN3
vanin 3
chr2_+_85981008 0.15 ENST00000306279.3
ATOH8
atonal homolog 8 (Drosophila)
chr1_-_219615984 0.15 ENST00000420762.1
RP11-95P13.1
RP11-95P13.1
chr14_-_73493825 0.15 ENST00000318876.5
ENST00000556143.1
ZFYVE1
zinc finger, FYVE domain containing 1
chr22_+_17082732 0.15 ENST00000558085.2
ENST00000592918.1
ENST00000400593.2
ENST00000592107.1
ENST00000426585.1
ENST00000591299.1
TPTEP1
transmembrane phosphatase with tensin homology pseudogene 1
chr13_-_41635512 0.15 ENST00000405737.2
ELF1
E74-like factor 1 (ets domain transcription factor)
chr6_+_3259148 0.15 ENST00000419065.2
ENST00000473000.2
ENST00000451246.2
ENST00000454610.2
PSMG4
proteasome (prosome, macropain) assembly chaperone 4
chr14_+_23067166 0.15 ENST00000216327.6
ENST00000542041.1
ABHD4
abhydrolase domain containing 4
chr6_-_131211534 0.15 ENST00000456097.2
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr22_+_31002779 0.14 ENST00000215838.3
TCN2
transcobalamin II
chr22_+_31003133 0.14 ENST00000405742.3
TCN2
transcobalamin II
chr16_-_30102547 0.14 ENST00000279386.2
TBX6
T-box 6
chr10_-_69991865 0.14 ENST00000373673.3
ATOH7
atonal homolog 7 (Drosophila)
chr4_-_23735183 0.14 ENST00000507666.1
RP11-380P13.2
RP11-380P13.2
chr11_+_124933191 0.14 ENST00000532000.1
ENST00000308074.4
SLC37A2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr3_-_52868931 0.14 ENST00000486659.1
MUSTN1
musculoskeletal, embryonic nuclear protein 1
chr20_+_33292068 0.14 ENST00000374810.3
ENST00000374809.2
ENST00000451665.1
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr2_-_69870747 0.14 ENST00000409068.1
AAK1
AP2 associated kinase 1
chr11_+_6411636 0.14 ENST00000299397.3
ENST00000356761.2
ENST00000342245.4
SMPD1
sphingomyelin phosphodiesterase 1, acid lysosomal
chr16_-_79634595 0.14 ENST00000326043.4
ENST00000393350.1
MAF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr17_-_8093471 0.14 ENST00000389017.4
C17orf59
chromosome 17 open reading frame 59
chr3_-_151176497 0.14 ENST00000282466.3
IGSF10
immunoglobulin superfamily, member 10
chr2_-_70409953 0.13 ENST00000419381.1
C2orf42
chromosome 2 open reading frame 42
chr7_+_48128816 0.13 ENST00000395564.4
UPP1
uridine phosphorylase 1
chr17_-_7493390 0.13 ENST00000538513.2
ENST00000570788.1
ENST00000250055.2
SOX15
SRY (sex determining region Y)-box 15
chr5_-_172755056 0.13 ENST00000520648.1
STC2
stanniocalcin 2
chr11_+_6411670 0.13 ENST00000530395.1
ENST00000527275.1
SMPD1
sphingomyelin phosphodiesterase 1, acid lysosomal
chr17_-_48133054 0.13 ENST00000499842.1
RP11-1094H24.4
RP11-1094H24.4
chr1_-_42384343 0.13 ENST00000372584.1
HIVEP3
human immunodeficiency virus type I enhancer binding protein 3
chr22_-_21580582 0.13 ENST00000424627.1
GGT2
gamma-glutamyltransferase 2
chr1_+_12042015 0.13 ENST00000412236.1
MFN2
mitofusin 2
chr8_-_135522425 0.12 ENST00000521673.1
ZFAT
zinc finger and AT hook domain containing
chr6_+_155334780 0.12 ENST00000538270.1
ENST00000535231.1
TIAM2
T-cell lymphoma invasion and metastasis 2
chr9_+_125796806 0.12 ENST00000373642.1
GPR21
G protein-coupled receptor 21
chr10_-_100206642 0.12 ENST00000361490.4
ENST00000338546.5
ENST00000325103.6
HPS1
Hermansky-Pudlak syndrome 1
chr2_-_176866978 0.12 ENST00000392540.2
ENST00000409660.1
ENST00000544803.1
ENST00000272748.4
KIAA1715
KIAA1715
chr8_+_71581565 0.12 ENST00000408926.3
ENST00000520030.1
XKR9
XK, Kell blood group complex subunit-related family, member 9
chr1_-_161014731 0.12 ENST00000368020.1
USF1
upstream transcription factor 1
chr8_+_107738240 0.12 ENST00000449762.2
ENST00000297447.6
OXR1
oxidation resistance 1
chr4_-_46391367 0.12 ENST00000503806.1
ENST00000356504.1
ENST00000514090.1
ENST00000506961.1
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr10_-_106240032 0.12 ENST00000447860.1
RP11-127O4.3
RP11-127O4.3
chr17_+_1627834 0.12 ENST00000419248.1
ENST00000418841.1
WDR81
WD repeat domain 81
chr11_+_71259466 0.12 ENST00000528743.2
KRTAP5-9
keratin associated protein 5-9
chr11_-_624926 0.12 ENST00000526077.1
ENST00000534311.1
ENST00000531088.1
ENST00000397542.2
CDHR5
cadherin-related family member 5
chr14_-_67826538 0.12 ENST00000553687.1
ATP6V1D
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
chr17_+_7341586 0.11 ENST00000575235.1
FGF11
fibroblast growth factor 11
chr19_+_18699599 0.11 ENST00000450195.2
C19orf60
chromosome 19 open reading frame 60
chr14_+_103388976 0.11 ENST00000299155.5
AMN
amnion associated transmembrane protein
chr7_+_48128316 0.11 ENST00000341253.4
UPP1
uridine phosphorylase 1
chr11_+_124932986 0.11 ENST00000407458.1
ENST00000298280.5
SLC37A2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr5_+_95066823 0.11 ENST00000506817.1
ENST00000379982.3
RHOBTB3
Rho-related BTB domain containing 3
chr3_-_194119083 0.11 ENST00000401815.1
GP5
glycoprotein V (platelet)
chr6_+_155470243 0.11 ENST00000456877.2
ENST00000528391.2
TIAM2
T-cell lymphoma invasion and metastasis 2
chr21_+_30672433 0.11 ENST00000451655.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr1_-_116926718 0.11 ENST00000598661.1
AL136376.1
Uncharacterized protein
chr16_-_67427389 0.11 ENST00000562206.1
ENST00000290942.5
ENST00000393957.2
TPPP3
tubulin polymerization-promoting protein family member 3
chr1_-_33647267 0.11 ENST00000291416.5
TRIM62
tripartite motif containing 62
chr19_+_7587555 0.11 ENST00000601003.1
MCOLN1
mucolipin 1
chr20_-_56195525 0.11 ENST00000371173.3
ENST00000395822.3
ENST00000340462.4
ENST00000343535.4
ZBP1
Z-DNA binding protein 1
chr12_-_54121261 0.11 ENST00000549784.1
ENST00000262059.4
CALCOCO1
calcium binding and coiled-coil domain 1
chr22_+_38071615 0.11 ENST00000215909.5
LGALS1
lectin, galactoside-binding, soluble, 1
chr19_+_57874835 0.11 ENST00000543226.1
ENST00000596755.1
ENST00000282282.3
ENST00000597658.1
TRAPPC2P1
ZNF547
AC003002.4
trafficking protein particle complex 2 pseudogene 1
zinc finger protein 547
Uncharacterized protein
chr7_+_99699179 0.11 ENST00000438383.1
ENST00000429084.1
ENST00000359593.4
ENST00000439416.1
AP4M1
adaptor-related protein complex 4, mu 1 subunit
chr22_-_30814469 0.11 ENST00000598426.1
KIAA1658
KIAA1658
chr17_+_42248063 0.11 ENST00000293414.1
ASB16
ankyrin repeat and SOCS box containing 16
chr17_-_54893250 0.11 ENST00000397862.2
C17orf67
chromosome 17 open reading frame 67
chr2_-_61245363 0.11 ENST00000316752.6
PUS10
pseudouridylate synthase 10
chr22_+_30792980 0.11 ENST00000403484.1
ENST00000405717.3
ENST00000402592.3
SEC14L2
SEC14-like 2 (S. cerevisiae)
chr10_+_22605374 0.11 ENST00000448361.1
COMMD3
COMM domain containing 3
chr6_-_26250835 0.11 ENST00000446824.2
HIST1H3F
histone cluster 1, H3f
chr4_+_78079570 0.11 ENST00000509972.1
CCNG2
cyclin G2
chr1_+_223101757 0.11 ENST00000284476.6
DISP1
dispatched homolog 1 (Drosophila)
chr14_+_53019993 0.10 ENST00000542169.2
ENST00000555622.1
GPR137C
G protein-coupled receptor 137C
chr10_+_1102721 0.10 ENST00000263150.4
WDR37
WD repeat domain 37
chr20_-_50418947 0.10 ENST00000371539.3
SALL4
spalt-like transcription factor 4
chr20_+_44098385 0.10 ENST00000217425.5
ENST00000339946.3
WFDC2
WAP four-disulfide core domain 2
chr7_+_18535893 0.10 ENST00000432645.2
ENST00000441542.2
HDAC9
histone deacetylase 9
chr16_-_18908196 0.10 ENST00000565324.1
ENST00000561947.1
SMG1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr8_-_27941380 0.10 ENST00000413272.2
ENST00000341513.6
NUGGC
nuclear GTPase, germinal center associated
chr4_+_165878100 0.10 ENST00000513876.2
FAM218A
family with sequence similarity 218, member A
chr17_+_6347729 0.10 ENST00000572447.1
FAM64A
family with sequence similarity 64, member A
chr3_+_159570722 0.10 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr11_+_20044096 0.10 ENST00000533917.1
NAV2
neuron navigator 2
chr8_+_86351056 0.10 ENST00000285381.2
CA3
carbonic anhydrase III, muscle specific
chr11_-_62323702 0.10 ENST00000530285.1
AHNAK
AHNAK nucleoprotein
chr19_-_8642289 0.10 ENST00000596675.1
ENST00000338257.8
MYO1F
myosin IF
chr8_+_81398444 0.10 ENST00000455036.3
ENST00000426744.2
ZBTB10
zinc finger and BTB domain containing 10
chr2_-_37311445 0.10 ENST00000233099.5
ENST00000354531.2
HEATR5B
HEAT repeat containing 5B
chr11_+_61722629 0.10 ENST00000526988.1
BEST1
bestrophin 1
chr19_+_50191921 0.10 ENST00000420022.3
ADM5
adrenomedullin 5 (putative)
chr14_-_53019211 0.10 ENST00000557374.1
ENST00000281741.4
TXNDC16
thioredoxin domain containing 16
chr5_-_95158644 0.10 ENST00000237858.6
GLRX
glutaredoxin (thioltransferase)
chr11_+_124932955 0.10 ENST00000403796.2
SLC37A2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr1_-_153931052 0.10 ENST00000368630.3
ENST00000368633.1
CRTC2
CREB regulated transcription coactivator 2
chr8_-_67579418 0.09 ENST00000310421.4
VCPIP1
valosin containing protein (p97)/p47 complex interacting protein 1
chr1_-_150669500 0.09 ENST00000271732.3
GOLPH3L
golgi phosphoprotein 3-like
chr17_-_21156578 0.09 ENST00000399011.2
ENST00000468196.1
C17orf103
chromosome 17 open reading frame 103
chr7_+_99699280 0.09 ENST00000421755.1
AP4M1
adaptor-related protein complex 4, mu 1 subunit
chr16_+_66914264 0.09 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
PDP2
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr16_-_67514982 0.09 ENST00000565835.1
ENST00000540149.1
ENST00000290949.3
ATP6V0D1
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr4_+_8183793 0.09 ENST00000509119.1
SH3TC1
SH3 domain and tetratricopeptide repeats 1
chr15_+_75628232 0.09 ENST00000267935.8
ENST00000567195.1
COMMD4
COMM domain containing 4

Network of associatons between targets according to the STRING database.

First level regulatory network of TFAP4_MSC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.1 0.5 GO:0006218 uridine catabolic process(GO:0006218)
0.1 0.3 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.1 0.3 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.1 0.2 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.2 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.1 0.2 GO:0021571 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.3 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 0.3 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.2 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 0.7 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.6 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.2 GO:0002086 diaphragm contraction(GO:0002086)
0.0 0.1 GO:0048627 myoblast development(GO:0048627)
0.0 0.2 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.2 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.0 0.0 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:0016999 antibiotic metabolic process(GO:0016999)
0.0 0.2 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.3 GO:0023021 termination of signal transduction(GO:0023021)
0.0 0.2 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.3 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.3 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 0.4 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.1 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.0 0.4 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.4 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.7 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.1 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 0.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.2 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.1 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.2 GO:0098704 fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.1 GO:0090677 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.0 0.2 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.3 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.0 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.0 0.1 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.3 GO:0030238 male sex determination(GO:0030238)
0.0 0.1 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.0 0.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0002317 plasma cell differentiation(GO:0002317) response to isolation stress(GO:0035900)
0.0 0.1 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.3 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.0 0.1 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.1 GO:0019086 late viral transcription(GO:0019086)
0.0 0.1 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.2 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.1 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.0 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.0 GO:2000573 positive regulation of DNA biosynthetic process(GO:2000573)
0.0 0.1 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.1 GO:0006788 heme oxidation(GO:0006788) negative regulation of mast cell cytokine production(GO:0032764)
0.0 0.0 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.0 0.6 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.0 GO:0031662 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.0 0.1 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.0 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.1 GO:1903285 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.0 0.1 GO:1904970 brush border assembly(GO:1904970)
0.0 0.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.2 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.1 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.0 GO:0043324 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.1 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.1 GO:1903401 L-lysine transmembrane transport(GO:1903401)
0.0 0.1 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115)
0.0 0.0 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.1 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.1 GO:0038183 bile acid signaling pathway(GO:0038183)
0.0 0.2 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.4 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.1 GO:0021554 optic nerve development(GO:0021554)
0.0 0.1 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.3 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 0.5 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 1.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.1 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.4 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.2 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 0.4 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.2 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.0 GO:0072534 perineuronal net(GO:0072534)
0.0 0.3 GO:0042599 lamellar body(GO:0042599)
0.0 0.2 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 1.2 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.1 0.3 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.1 0.5 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.1 0.4 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.1 0.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.2 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.1 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.4 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0030395 lactose binding(GO:0030395)
0.0 1.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0052594 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.2 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.3 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.2 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.1 GO:0070984 SET domain binding(GO:0070984)
0.0 0.1 GO:0072545 tyrosine binding(GO:0072545)
0.0 0.1 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.4 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.4 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.5 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.5 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.3 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)