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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TFEC_MITF_ARNTL_BHLHE41

Z-value: 1.26

Motif logo

Transcription factors associated with TFEC_MITF_ARNTL_BHLHE41

Gene Symbol Gene ID Gene Info
ENSG00000105967.11 transcription factor EC
ENSG00000187098.10 melanocyte inducing transcription factor
ENSG00000133794.13 aryl hydrocarbon receptor nuclear translocator like
ENSG00000123095.5 basic helix-loop-helix family member e41

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ARNTLhg19_v2_chr11_+_13299186_13299432-0.834.2e-02Click!
TFEChg19_v2_chr7_-_115670792_1156707980.824.5e-02Click!
MITFhg19_v2_chr3_+_69812877_69812962-0.701.2e-01Click!
BHLHE41hg19_v2_chr12_-_26278030_26278060-0.266.2e-01Click!

Activity profile of TFEC_MITF_ARNTL_BHLHE41 motif

Sorted Z-values of TFEC_MITF_ARNTL_BHLHE41 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_62223320 1.61 ENST00000580828.1
ENST00000582965.1
small nucleolar RNA, H/ACA box 76
chr11_+_67159416 1.46 ENST00000307980.2
ENST00000544620.1
RAD9 homolog A (S. pombe)
chr17_-_6915646 1.33 ENST00000574377.1
ENST00000399541.2
ENST00000399540.2
ENST00000575727.1
ENST00000573939.1
Uncharacterized protein
chr19_-_10764509 1.23 ENST00000591501.1
ILF3 antisense RNA 1 (head to head)
chr12_+_112451222 1.09 ENST00000552052.1
endoplasmic reticulum protein 29
chr1_+_3816936 1.05 ENST00000413332.1
ENST00000442673.1
ENST00000439488.1
long intergenic non-protein coding RNA 1134
chr10_-_46089939 1.05 ENST00000453980.3
membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
chr6_-_109703663 1.01 ENST00000368961.5
CD164 molecule, sialomucin
chr5_+_150827143 0.90 ENST00000243389.3
ENST00000517945.1
ENST00000521925.1
solute carrier family 36 (proton/amino acid symporter), member 1
chr8_+_103876528 0.86 ENST00000522939.1
ENST00000524007.1
HCG15011, isoform CRA_a; Protein LOC100996457
chr9_-_37576333 0.84 ENST00000541607.1
F-box protein 10
chr2_+_220042933 0.84 ENST00000430297.2
family with sequence similarity 134, member A
chr7_+_99070527 0.81 ENST00000379724.3
zinc finger protein 789
chr6_-_109703634 0.81 ENST00000324953.5
ENST00000310786.4
ENST00000275080.7
ENST00000413644.2
CD164 molecule, sialomucin
chr19_+_40854363 0.79 ENST00000599685.1
ENST00000392032.2
phospholipase D family, member 3
chr16_-_28503327 0.78 ENST00000535392.1
ENST00000395653.4
ceroid-lipofuscinosis, neuronal 3
chr16_+_2570340 0.74 ENST00000568263.1
ENST00000293971.6
ENST00000302956.4
ENST00000413459.3
ENST00000566706.1
ENST00000569879.1
amidohydrolase domain containing 2
chr17_-_7137857 0.73 ENST00000005340.5
dishevelled segment polarity protein 2
chr2_-_220042825 0.72 ENST00000409789.1
cyclin Pas1/PHO80 domain containing 1
chr5_+_133706865 0.72 ENST00000265339.2
ubiquitin-conjugating enzyme E2B
chr18_+_9136758 0.72 ENST00000383440.2
ENST00000262126.4
ENST00000577992.1
ankyrin repeat domain 12
chr14_-_54955721 0.67 ENST00000554908.1
glia maturation factor, beta
chr1_+_44440575 0.66 ENST00000532642.1
ENST00000236067.4
ENST00000471859.2
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr11_+_18344106 0.65 ENST00000534641.1
ENST00000525831.1
ENST00000265963.4
general transcription factor IIH, polypeptide 1, 62kDa
chr4_-_113627966 0.64 ENST00000505632.1
RP11-148B6.2
chr16_-_28503080 0.63 ENST00000565316.1
ENST00000565778.1
ENST00000357857.9
ENST00000568558.1
ENST00000357806.7
ceroid-lipofuscinosis, neuronal 3
chr12_+_123849462 0.62 ENST00000543072.1
hsa-mir-8072
chr5_-_150138246 0.61 ENST00000518015.1
dynactin 4 (p62)
chr16_-_67514982 0.60 ENST00000565835.1
ENST00000540149.1
ENST00000290949.3
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr1_-_21995794 0.60 ENST00000542643.2
ENST00000374765.4
ENST00000317967.7
RAP1 GTPase activating protein
chr12_-_58146128 0.59 ENST00000551800.1
ENST00000549606.1
ENST00000257904.6
cyclin-dependent kinase 4
chr14_-_20929624 0.59 ENST00000398020.4
ENST00000250489.4
transmembrane protein 55B
chr16_-_58718638 0.57 ENST00000562397.1
ENST00000564010.1
ENST00000570214.1
ENST00000563196.1
solute carrier family 38, member 7
chr12_-_121972556 0.56 ENST00000545022.1
lysine (K)-specific demethylase 2B
chr11_+_59522837 0.56 ENST00000437946.2
syntaxin 3
chr1_+_11866207 0.56 ENST00000312413.6
ENST00000346436.6
chloride channel, voltage-sensitive 6
chr19_+_1275917 0.55 ENST00000469144.1
chromosome 19 open reading frame 24
chr22_-_50699972 0.55 ENST00000395778.3
mitogen-activated protein kinase 12
chr15_-_72668805 0.55 ENST00000268097.5
hexosaminidase A (alpha polypeptide)
chr12_+_56109810 0.54 ENST00000550412.1
ENST00000257899.2
ENST00000548925.1
ENST00000549147.1
Uncharacterized protein
biogenesis of lysosomal organelles complex-1, subunit 1
chr12_-_58146048 0.54 ENST00000547281.1
ENST00000546489.1
ENST00000552388.1
ENST00000540325.1
ENST00000312990.6
cyclin-dependent kinase 4
chr11_-_85780086 0.53 ENST00000532317.1
ENST00000528256.1
ENST00000526033.1
phosphatidylinositol binding clathrin assembly protein
chr19_+_49458107 0.53 ENST00000539787.1
ENST00000345358.7
ENST00000391871.3
ENST00000415969.2
ENST00000354470.3
ENST00000506183.1
ENST00000293288.8
BCL2-associated X protein
chr2_-_47572105 0.52 ENST00000419035.1
ENST00000448713.1
ENST00000450550.1
ENST00000413185.2
AC073283.4
chr2_-_172967621 0.52 ENST00000234198.4
ENST00000466293.2
distal-less homeobox 2
chr2_+_223916862 0.51 ENST00000604125.1
potassium voltage-gated channel, Isk-related family, member 4
chr9_-_90589586 0.51 ENST00000325303.8
ENST00000375883.3
cyclin-dependent kinase 20
chr16_-_1525016 0.50 ENST00000262318.8
ENST00000448525.1
chloride channel, voltage-sensitive 7
chr19_+_7587491 0.50 ENST00000264079.6
mucolipin 1
chr19_-_11688260 0.50 ENST00000590832.1
acid phosphatase 5, tartrate resistant
chr22_-_38577782 0.50 ENST00000430886.1
ENST00000332509.3
ENST00000447598.2
ENST00000435484.1
ENST00000402064.1
ENST00000436218.1
phospholipase A2, group VI (cytosolic, calcium-independent)
chr15_+_44084040 0.50 ENST00000249786.4
small EDRK-rich factor 2
chr16_+_28985542 0.49 ENST00000567771.1
ENST00000568388.1
spinster homolog 1 (Drosophila)
chr6_+_151773583 0.49 ENST00000545879.1
chromosome 6 open reading frame 211
chr3_-_126076264 0.48 ENST00000296233.3
Kruppel-like factor 15
chr22_+_31002990 0.48 ENST00000423350.1
transcobalamin II
chr7_+_116593536 0.48 ENST00000417919.1
suppression of tumorigenicity 7
chr12_+_54426637 0.47 ENST00000312492.2
homeobox C5
chr16_+_28986085 0.47 ENST00000565975.1
ENST00000311008.11
ENST00000323081.8
ENST00000334536.8
spinster homolog 1 (Drosophila)
chr16_-_58718611 0.45 ENST00000564100.1
ENST00000570101.1
solute carrier family 38, member 7
chr8_-_95274536 0.45 ENST00000297596.2
ENST00000396194.2
GTP binding protein overexpressed in skeletal muscle
chr14_-_68283291 0.45 ENST00000555452.1
ENST00000347230.4
zinc finger, FYVE domain containing 26
chr1_+_11866270 0.44 ENST00000376497.3
ENST00000376487.3
ENST00000376496.3
chloride channel, voltage-sensitive 6
chr1_+_10093188 0.43 ENST00000377153.1
ubiquitination factor E4B
chr14_-_92572894 0.43 ENST00000532032.1
ENST00000506466.1
ENST00000555381.1
ENST00000557311.1
ENST00000554592.1
ENST00000554672.1
ENST00000553491.1
ENST00000556220.1
ENST00000502250.1
ENST00000503767.1
ENST00000393287.5
ENST00000340660.6
ENST00000545170.1
ENST00000429774.2
ataxin 3
chr16_+_31044812 0.43 ENST00000313843.3
syntaxin 4
chrX_+_100878079 0.42 ENST00000471229.2
armadillo repeat containing, X-linked 3
chr4_+_76439649 0.42 ENST00000507557.1
THAP domain containing 6
chr19_+_41305330 0.42 ENST00000593972.1
egl-9 family hypoxia-inducible factor 2
chr11_-_71814276 0.42 ENST00000538404.1
ENST00000535107.1
ENST00000545249.1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr2_-_220083671 0.42 ENST00000439002.2
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr11_-_36310958 0.42 ENST00000532705.1
ENST00000263401.5
ENST00000452374.2
COMM domain containing 9
chr22_+_31003133 0.41 ENST00000405742.3
transcobalamin II
chr11_-_61560254 0.40 ENST00000543510.1
transmembrane protein 258
chr5_-_110074603 0.39 ENST00000515278.2
transmembrane protein 232
chr2_+_176981307 0.39 ENST00000249501.4
homeobox D10
chr21_-_46492927 0.39 ENST00000599569.1
Uncharacterized protein
chr6_-_163834852 0.39 ENST00000604200.1
colon adenocarcinoma hypermethylated (non-protein coding)
chr15_+_44084503 0.39 ENST00000409960.2
ENST00000409646.1
ENST00000594896.1
ENST00000339624.5
ENST00000409291.1
ENST00000402131.1
ENST00000403425.1
ENST00000430901.1
small EDRK-rich factor 2
chr6_+_131571535 0.39 ENST00000474850.2
A kinase (PRKA) anchor protein 7
chr16_-_5083589 0.39 ENST00000563578.1
ENST00000562346.2
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr6_+_36562132 0.39 ENST00000373715.6
ENST00000339436.7
serine/arginine-rich splicing factor 3
chr13_+_113951607 0.39 ENST00000397181.3
lysosomal-associated membrane protein 1
chr2_+_228190066 0.38 ENST00000436237.1
ENST00000443428.2
ENST00000418961.1
mitochondrial fission factor
chr2_+_232575168 0.38 ENST00000440384.1
prothymosin, alpha
chr7_+_4815238 0.38 ENST00000348624.4
ENST00000401897.1
adaptor-related protein complex 5, zeta 1 subunit
chr9_-_37576226 0.38 ENST00000432825.2
F-box protein 10
chr11_-_61560053 0.38 ENST00000537328.1
transmembrane protein 258
chr3_-_170626376 0.38 ENST00000487522.1
ENST00000474417.1
eukaryotic translation initiation factor 5A2
chr11_+_118938485 0.37 ENST00000300793.6
vacuolar protein sorting 11 homolog (S. cerevisiae)
chr19_-_40854417 0.37 ENST00000582006.1
ENST00000582783.1
chromosome 19 open reading frame 47
chr22_-_39637135 0.37 ENST00000440375.1
platelet-derived growth factor beta polypeptide
chr9_-_90589402 0.37 ENST00000375871.4
ENST00000605159.1
ENST00000336654.5
cyclin-dependent kinase 20
chr15_+_45879964 0.36 ENST00000565409.1
ENST00000564765.1
biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
chr1_-_183538319 0.36 ENST00000420553.1
ENST00000419402.1
neutrophil cytosolic factor 2
chr17_-_47841485 0.36 ENST00000506156.1
ENST00000240364.2
family with sequence similarity 117, member A
chr1_-_155211017 0.35 ENST00000536770.1
ENST00000368373.3
glucosidase, beta, acid
chr12_+_113796347 0.35 ENST00000545182.2
ENST00000280800.3
phospholipase B domain containing 2
chr6_-_33385870 0.35 ENST00000488034.1
cutA divalent cation tolerance homolog (E. coli)
chr17_+_46970178 0.35 ENST00000393366.2
ENST00000506855.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr1_-_68962744 0.34 ENST00000525124.1
DEP domain containing 1
chr15_-_72668185 0.34 ENST00000457859.2
ENST00000566304.1
ENST00000567159.1
ENST00000429918.2
hexosaminidase A (alpha polypeptide)
chr17_+_42015654 0.34 ENST00000565120.1
Uncharacterized protein
chr2_+_74212073 0.34 ENST00000441217.1
AC073046.25
chr19_+_8386371 0.34 ENST00000600659.2
ribosomal protein S28
chr6_-_33385902 0.34 ENST00000374500.5
cutA divalent cation tolerance homolog (E. coli)
chr6_-_109703600 0.34 ENST00000512821.1
CD164 molecule, sialomucin
chr19_-_5680499 0.34 ENST00000587589.1
chromosome 19 open reading frame 70
chr17_-_48450534 0.34 ENST00000503633.1
ENST00000442592.3
ENST00000225969.4
mitochondrial ribosomal protein L27
chr21_-_36421401 0.33 ENST00000486278.2
runt-related transcription factor 1
chr5_-_132299313 0.33 ENST00000265343.5
AF4/FMR2 family, member 4
chr17_-_42200996 0.33 ENST00000587135.1
ENST00000225983.6
ENST00000393622.2
ENST00000588703.1
histone deacetylase 5
chr6_+_139349903 0.33 ENST00000461027.1
ABRA C-terminal like
chr8_+_71581565 0.33 ENST00000408926.3
ENST00000520030.1
XK, Kell blood group complex subunit-related family, member 9
chr1_+_26758849 0.33 ENST00000533087.1
ENST00000531312.1
ENST00000525165.1
ENST00000525326.1
ENST00000525546.1
ENST00000436153.2
ENST00000530781.1
dehydrodolichyl diphosphate synthase
chr6_+_87865262 0.32 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
zinc finger protein 292
chr7_+_916183 0.32 ENST00000265857.3
golgi to ER traffic protein 4 homolog (S. cerevisiae)
chr17_-_58469591 0.32 ENST00000589335.1
ubiquitin specific peptidase 32
chr12_-_76953349 0.32 ENST00000551927.1
oxysterol binding protein-like 8
chr6_-_33385854 0.32 ENST00000488478.1
cutA divalent cation tolerance homolog (E. coli)
chr3_-_20227619 0.32 ENST00000425061.1
ENST00000443724.1
ENST00000421451.1
ENST00000452020.1
ENST00000417364.1
ENST00000306698.2
ENST00000419233.2
ENST00000263753.4
ENST00000383774.1
ENST00000437051.1
ENST00000412868.1
ENST00000429446.3
ENST00000442720.1
shugoshin-like 1 (S. pombe)
chr17_-_8059638 0.32 ENST00000584202.1
ENST00000354903.5
ENST00000577253.1
period circadian clock 1
chr2_-_220083692 0.32 ENST00000265316.3
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr19_+_10764937 0.31 ENST00000449870.1
ENST00000318511.3
ENST00000420083.1
interleukin enhancer binding factor 3, 90kDa
chr16_+_29127282 0.31 ENST00000562902.1
RP11-426C22.5
chr5_+_176730769 0.31 ENST00000303204.4
ENST00000503216.1
PRELI domain containing 1
chr19_+_11546440 0.31 ENST00000589126.1
ENST00000588269.1
ENST00000587509.1
ENST00000592741.1
ENST00000593101.1
ENST00000587327.1
protein kinase C substrate 80K-H
chr1_-_155211065 0.31 ENST00000427500.3
glucosidase, beta, acid
chr19_-_8386238 0.31 ENST00000301457.2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
chr12_+_6644443 0.31 ENST00000396858.1
glyceraldehyde-3-phosphate dehydrogenase
chr16_+_84002234 0.31 ENST00000305202.4
N-terminal EF-hand calcium binding protein 2
chr12_+_56110315 0.31 ENST00000548556.1
biogenesis of lysosomal organelles complex-1, subunit 1
chr4_+_76439095 0.31 ENST00000506261.1
THAP domain containing 6
chr15_-_83316254 0.30 ENST00000567678.1
ENST00000450751.2
cytoplasmic polyadenylation element binding protein 1
chr22_-_38577731 0.30 ENST00000335539.3
phospholipase A2, group VI (cytosolic, calcium-independent)
chr11_-_2906979 0.30 ENST00000380725.1
ENST00000313407.6
ENST00000430149.2
ENST00000440480.2
ENST00000414822.3
cyclin-dependent kinase inhibitor 1C (p57, Kip2)
chr22_-_42342692 0.30 ENST00000404067.1
ENST00000402338.1
centromere protein M
chr16_+_5121814 0.30 ENST00000262374.5
ENST00000586840.1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr11_-_71814422 0.30 ENST00000278671.5
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr1_+_150229554 0.30 ENST00000369111.4
carbonic anhydrase XIV
chr16_+_31044413 0.30 ENST00000394998.1
syntaxin 4
chr19_+_11546153 0.29 ENST00000591946.1
ENST00000252455.2
ENST00000412601.1
protein kinase C substrate 80K-H
chr1_-_183604794 0.29 ENST00000367534.1
ENST00000359856.6
ENST00000294742.6
actin related protein 2/3 complex, subunit 5, 16kDa
chr15_-_83315874 0.29 ENST00000569257.1
cytoplasmic polyadenylation element binding protein 1
chr20_+_44520009 0.29 ENST00000607482.1
ENST00000372459.2
cathepsin A
chr19_+_35810164 0.29 ENST00000598537.1
CD22 molecule
chr22_+_40573921 0.29 ENST00000454349.2
ENST00000335727.9
trinucleotide repeat containing 6B
chr16_-_5083917 0.29 ENST00000312251.3
ENST00000381955.3
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr7_+_99775366 0.29 ENST00000394018.2
ENST00000416412.1
stromal antigen 3
chrX_+_55744166 0.28 ENST00000374941.4
ENST00000414239.1
Ras-related GTP binding B
chr7_+_99070464 0.28 ENST00000331410.5
ENST00000483089.1
ENST00000448667.1
ENST00000493485.1
zinc finger protein 789
chr12_-_76953453 0.28 ENST00000549570.1
oxysterol binding protein-like 8
chr8_-_145688231 0.28 ENST00000530374.1
cysteine/histidine-rich 1
chr22_-_39268192 0.28 ENST00000216083.6
chromobox homolog 6
chr19_+_10812108 0.28 ENST00000250237.5
ENST00000592254.1
queuine tRNA-ribosyltransferase 1
chr12_+_54332535 0.27 ENST00000243056.3
homeobox C13
chr17_+_45401308 0.27 ENST00000331493.2
ENST00000519772.1
ENST00000517484.1
EF-hand calcium binding domain 13
chr15_+_75628419 0.27 ENST00000567377.1
ENST00000562789.1
ENST00000568301.1
COMM domain containing 4
chr2_+_85981008 0.27 ENST00000306279.3
atonal homolog 8 (Drosophila)
chr19_+_10765003 0.27 ENST00000407004.3
ENST00000589998.1
ENST00000589600.1
interleukin enhancer binding factor 3, 90kDa
chr17_-_7137582 0.27 ENST00000575756.1
ENST00000575458.1
dishevelled segment polarity protein 2
chr11_+_64001962 0.27 ENST00000309422.2
vascular endothelial growth factor B
chr11_+_327171 0.27 ENST00000534483.1
ENST00000524824.1
ENST00000531076.1
RP11-326C3.12
chr7_-_127032114 0.27 ENST00000436992.1
zinc finger protein 800
chr6_-_84937314 0.26 ENST00000257766.4
ENST00000403245.3
KIAA1009
chr19_-_15236470 0.26 ENST00000533747.1
ENST00000598709.1
ENST00000534378.1
ilvB (bacterial acetolactate synthase)-like
chr8_+_67039131 0.26 ENST00000315962.4
ENST00000353317.5
tripartite motif containing 55
chr8_+_109455830 0.26 ENST00000524143.1
ER membrane protein complex subunit 2
chr14_+_102414651 0.26 ENST00000607414.1
RP11-1017G21.5
chr19_+_8740061 0.26 ENST00000593792.1
CTD-2586B10.1
chrX_+_72783026 0.26 ENST00000373504.6
ENST00000373502.5
cysteine-rich hydrophobic domain 1
chr22_-_39636914 0.26 ENST00000381551.4
platelet-derived growth factor beta polypeptide
chr14_-_20922960 0.26 ENST00000553640.1
ENST00000488532.2
O-sialoglycoprotein endopeptidase
chrX_+_101380642 0.26 ENST00000372780.1
ENST00000329035.2
transcription elongation factor A (SII)-like 2
chr7_-_92465868 0.26 ENST00000424848.2
cyclin-dependent kinase 6
chr19_+_40854559 0.25 ENST00000598962.1
ENST00000409419.1
ENST00000409587.1
ENST00000602131.1
ENST00000409735.4
ENST00000600948.1
ENST00000356508.5
ENST00000596682.1
ENST00000594908.1
phospholipase D family, member 3
chr14_-_81687197 0.25 ENST00000553612.1
general transcription factor IIA, 1, 19/37kDa
chr17_-_48450265 0.25 ENST00000507088.1
mitochondrial ribosomal protein L27
chrX_+_102883620 0.25 ENST00000372626.3
transcription elongation factor A (SII)-like 1
chr13_+_36920569 0.25 ENST00000379848.2
SPG20 opposite strand
chr5_-_175964366 0.25 ENST00000274811.4
ring finger protein 44
chr17_-_39341594 0.25 ENST00000398472.1
keratin associated protein 4-1
chr19_+_7587555 0.25 ENST00000601003.1
mucolipin 1
chr19_+_50031547 0.24 ENST00000597801.1
reticulocalbin 3, EF-hand calcium binding domain
chr19_-_15236562 0.24 ENST00000263383.3
ilvB (bacterial acetolactate synthase)-like
chr22_-_39096981 0.24 ENST00000427389.1
Josephin domain containing 1
chr19_-_11545920 0.24 ENST00000356392.4
ENST00000591179.1
coiled-coil domain containing 151
chr2_-_26569611 0.24 ENST00000541401.1
ENST00000433584.1
ENST00000333478.6
G protein-coupled receptor 113
chr5_-_1799965 0.24 ENST00000508987.1
mitochondrial ribosomal protein L36
chr10_+_22610124 0.24 ENST00000376663.3
BMI1 polycomb ring finger oncogene
chr19_-_5720248 0.24 ENST00000360614.3
lon peptidase 1, mitochondrial
chrX_-_45629661 0.24 ENST00000602507.1
ENST00000602461.1
RP6-99M1.2
chrX_+_146993648 0.24 ENST00000370470.1
fragile X mental retardation 1
chr3_+_49044765 0.24 ENST00000429900.2
WD repeat domain 6
chr15_-_50978965 0.24 ENST00000560955.1
ENST00000313478.7
transient receptor potential cation channel, subfamily M, member 7
chr19_+_11546093 0.23 ENST00000591462.1
protein kinase C substrate 80K-H
chr22_+_31002779 0.23 ENST00000215838.3
transcobalamin II
chr9_+_34646624 0.23 ENST00000450095.2
ENST00000556278.1
galactose-1-phosphate uridylyltransferase
Uncharacterized protein
chr1_+_221051699 0.23 ENST00000366903.6
H2.0-like homeobox
chr17_-_42200958 0.23 ENST00000336057.5
histone deacetylase 5

Network of associatons between targets according to the STRING database.

First level regulatory network of TFEC_MITF_ARNTL_BHLHE41

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.3 0.8 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.3 1.0 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.2 0.7 GO:0043311 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) regulation of eosinophil activation(GO:1902566) positive regulation of eosinophil activation(GO:1902568)
0.2 0.7 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.2 1.7 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.2 1.1 GO:0043335 protein unfolding(GO:0043335)
0.2 1.9 GO:0015808 L-alanine transport(GO:0015808)
0.2 0.6 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.2 0.5 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.2 0.7 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.2 0.5 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.2 0.7 GO:1901804 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.2 1.0 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.2 0.3 GO:1904378 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.2 0.6 GO:1905174 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.2 0.5 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.1 0.4 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.1 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 0.5 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.1 1.3 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.9 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 0.3 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.1 0.3 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.6 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 0.8 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.1 0.2 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.1 0.5 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 0.2 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.1 0.3 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168) regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 0.1 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.1 0.2 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.1 0.2 GO:1902559 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.1 1.0 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 1.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.1 0.7 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.1 0.5 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.1 0.5 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.9 GO:0060155 platelet dense granule organization(GO:0060155)
0.1 0.2 GO:1903567 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 0.6 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.2 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.7 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.7 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.2 GO:0006043 glucosamine catabolic process(GO:0006043)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.1 GO:1900075 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.0 0.7 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.2 GO:2000506 negative regulation of energy homeostasis(GO:2000506)
0.0 0.9 GO:0015886 heme transport(GO:0015886)
0.0 0.5 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.4 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.2 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.4 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.1 GO:1903056 regulation of melanosome organization(GO:1903056)
0.0 0.8 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.2 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.0 0.3 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.4 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 1.7 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.1 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.1 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.1 GO:0061433 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.0 0.0 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.2 GO:0034036 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.0 0.1 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232)
0.0 0.9 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:2000537 regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.0 0.1 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.3 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.2 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.1 GO:1904925 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0 0.4 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.5 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.4 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.0 2.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.2 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.1 GO:1904482 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.0 0.7 GO:0007097 nuclear migration(GO:0007097)
0.0 0.1 GO:1905123 regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123)
0.0 0.2 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.3 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.0 0.1 GO:0002572 pro-T cell differentiation(GO:0002572) regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.0 0.3 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.2 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.0 0.3 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.1 GO:0006147 guanine catabolic process(GO:0006147)
0.0 0.2 GO:0021546 rhombomere development(GO:0021546)
0.0 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.1 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.1 GO:0090301 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 1.0 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.2 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.0 0.2 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.1 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 0.2 GO:0010259 multicellular organism aging(GO:0010259)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.6 GO:0033572 transferrin transport(GO:0033572)
0.0 0.7 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.0 0.1 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.8 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.4 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.2 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.1 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.0 GO:0050787 detoxification of mercury ion(GO:0050787)
0.0 0.3 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.6 GO:2000615 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051) regulation of histone H3-K9 acetylation(GO:2000615)
0.0 0.0 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.3 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.0 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.9 GO:1904031 positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.4 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.5 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.2 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.2 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.4 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.0 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.0 0.1 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.0 0.1 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.1 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.1 GO:0006788 heme oxidation(GO:0006788) negative regulation of mast cell cytokine production(GO:0032764)
0.0 0.0 GO:0015883 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.0 0.3 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.0 0.0 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.0 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0072093 ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.0 0.1 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.2 GO:0007379 segment specification(GO:0007379)
0.0 0.4 GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.0 GO:0019516 lactate oxidation(GO:0019516)
0.0 0.1 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.0 0.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.1 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 0.5 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112)
0.0 0.0 GO:0034759 regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759)
0.0 0.1 GO:2000683 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) regulation of cellular response to X-ray(GO:2000683) positive regulation of cellular response to X-ray(GO:2000685)
0.0 0.2 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 0.1 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0071486 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.0 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.0 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.1 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0 0.0 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.7 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.1 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.3 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 0.4 GO:0045730 respiratory burst(GO:0045730)
0.0 0.2 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.0 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.0 0.1 GO:0071400 cellular response to oleic acid(GO:0071400)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.5 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.1 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.2 GO:0021554 optic nerve development(GO:0021554)
0.0 0.1 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0 0.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 0.4 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.2 0.5 GO:1902737 dendritic filopodium(GO:1902737)
0.1 1.3 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.6 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 0.7 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.9 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.6 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.6 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 0.8 GO:0032010 phagolysosome(GO:0032010)
0.1 0.8 GO:0033503 HULC complex(GO:0033503)
0.1 0.5 GO:0097452 GAIT complex(GO:0097452)
0.1 0.9 GO:0071986 Ragulator complex(GO:0071986)
0.1 0.2 GO:0035101 FACT complex(GO:0035101)
0.1 0.4 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.1 0.3 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 0.7 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.7 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.7 GO:0005869 dynactin complex(GO:0005869)
0.0 0.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.4 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.3 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
0.0 0.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.3 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.5 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.3 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.1 GO:0019034 viral replication complex(GO:0019034)
0.0 1.1 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.1 GO:0001534 radial spoke(GO:0001534)
0.0 0.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.2 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.2 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279) symmetric synapse(GO:0032280)
0.0 0.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 11.6 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.3 GO:0000243 commitment complex(GO:0000243)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0090661 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.3 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 1.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.2 GO:0031982 vesicle(GO:0031982)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.0 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.0 0.1 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 1.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0036338 viral envelope(GO:0019031) viral membrane(GO:0036338)
0.0 0.1 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.0 0.0 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.0 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.1 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.5 GO:0051233 spindle midzone(GO:0051233)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.2 0.7 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.2 1.5 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.2 1.9 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.2 1.2 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.2 0.7 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.2 0.5 GO:0070362 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.2 0.8 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.7 GO:0004348 glucosylceramidase activity(GO:0004348)
0.1 0.5 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.1 1.3 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.9 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 1.0 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.3 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.2 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.1 0.3 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.3 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 1.0 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 0.8 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 0.2 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1 0.2 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.5 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.6 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 0.2 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.1 0.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.3 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.6 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.1 0.2 GO:0016250 N-sulfoglucosamine sulfohydrolase activity(GO:0016250) hydrolase activity, acting on acid sulfur-nitrogen bonds(GO:0016826)
0.1 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.6 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.3 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 1.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.2 GO:0004461 lactose synthase activity(GO:0004461)
0.1 0.8 GO:0015929 hexosaminidase activity(GO:0015929)
0.1 0.2 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.3 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.7 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.8 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.8 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.3 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.5 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.3 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.0 1.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.5 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.6 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 1.0 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.2 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0031177 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) S-acetyltransferase activity(GO:0016418) phosphopantetheine binding(GO:0031177)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.1 GO:0072545 tyrosine binding(GO:0072545)
0.0 0.1 GO:0008892 guanine deaminase activity(GO:0008892)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.2 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.0 0.9 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.2 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.4 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.2 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.0 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.0 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.0 0.0 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.5 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.0 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.0 GO:0032093 SAM domain binding(GO:0032093)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.6 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.0 GO:0004458 D-lactate dehydrogenase (cytochrome) activity(GO:0004458) oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor(GO:0016898)
0.0 0.2 GO:0005542 folic acid binding(GO:0005542)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.0 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.1 GO:0035501 MH1 domain binding(GO:0035501)
0.0 0.1 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.1 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.2 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.0 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.0 0.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.4 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.1 GO:1990446 U1 snRNP binding(GO:1990446)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.0 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.1 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.6 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.4 PID ATR PATHWAY ATR signaling pathway
0.0 0.8 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.5 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 1.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.8 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.8 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.7 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.6 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.4 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.5 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.7 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.8 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.8 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.0 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 1.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.1 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.6 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 1.3 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis