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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TGIF1

Z-value: 0.80

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Transcription factors associated with TGIF1

Gene Symbol Gene ID Gene Info
TGIF1
ENSG00000177426.16 TGFB induced factor homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TGIF1hg19_v2_chr18_+_3449695_3449712-0.777.4e-02Click!

Activity profile of TGIF1 motif

Sorted Z-values of TGIF1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_25348186 0.57 ENST00000555711.1
ENST00000556885.1
ENST00000554266.1
ENST00000556351.1
ENST00000556927.1
ENST00000556402.1
ENST00000553788.1
LYRM5
LYR motif containing 5
chr6_+_80714332 0.53 ENST00000502580.1
ENST00000511260.1
TTK
TTK protein kinase
chr8_+_71485681 0.48 ENST00000391684.1
AC120194.1
AC120194.1
chr8_+_72755367 0.48 ENST00000537896.1
RP11-383H13.1
Protein LOC100132891; cDNA FLJ53548
chr20_-_31124186 0.44 ENST00000375678.3
C20orf112
chromosome 20 open reading frame 112
chr1_-_65533390 0.38 ENST00000448344.1
RP4-535B20.1
RP4-535B20.1
chr6_+_131521120 0.38 ENST00000537868.1
AKAP7
A kinase (PRKA) anchor protein 7
chr1_+_95616933 0.37 ENST00000604203.1
RP11-57H12.6
TMEM56-RWDD3 readthrough
chr5_-_66942617 0.37 ENST00000507298.1
RP11-83M16.5
RP11-83M16.5
chr6_+_80714318 0.37 ENST00000369798.2
TTK
TTK protein kinase
chr12_+_25348139 0.35 ENST00000557540.2
ENST00000381356.4
LYRM5
LYR motif containing 5
chr2_+_37311588 0.34 ENST00000409774.1
ENST00000608836.1
GPATCH11
G patch domain containing 11
chr18_-_54318353 0.31 ENST00000590954.1
ENST00000540155.1
TXNL1
thioredoxin-like 1
chr1_-_193075180 0.31 ENST00000367440.3
GLRX2
glutaredoxin 2
chr6_-_97731019 0.28 ENST00000275053.4
MMS22L
MMS22-like, DNA repair protein
chr17_-_66287350 0.26 ENST00000580666.1
ENST00000583477.1
SLC16A6
solute carrier family 16, member 6
chr14_+_31494672 0.26 ENST00000542754.2
ENST00000313566.6
AP4S1
adaptor-related protein complex 4, sigma 1 subunit
chr10_+_94608245 0.25 ENST00000443748.2
ENST00000260762.6
EXOC6
exocyst complex component 6
chr2_+_37311645 0.25 ENST00000281932.5
GPATCH11
G patch domain containing 11
chr7_+_95401877 0.25 ENST00000524053.1
ENST00000324972.6
ENST00000537881.1
ENST00000437599.1
ENST00000359388.4
ENST00000413338.1
DYNC1I1
dynein, cytoplasmic 1, intermediate chain 1
chr10_+_98592674 0.24 ENST00000356016.3
ENST00000371097.4
LCOR
ligand dependent nuclear receptor corepressor
chr4_-_175443943 0.24 ENST00000296522.6
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr2_+_118846008 0.24 ENST00000245787.4
INSIG2
insulin induced gene 2
chr2_-_179914760 0.23 ENST00000420890.2
ENST00000409284.1
ENST00000443758.1
ENST00000446116.1
CCDC141
coiled-coil domain containing 141
chr22_+_17082732 0.23 ENST00000558085.2
ENST00000592918.1
ENST00000400593.2
ENST00000592107.1
ENST00000426585.1
ENST00000591299.1
TPTEP1
transmembrane phosphatase with tensin homology pseudogene 1
chr3_+_122920847 0.23 ENST00000466519.1
ENST00000480631.1
ENST00000491366.1
ENST00000487572.1
SEC22A
SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
chr1_-_220608023 0.23 ENST00000416839.2
AC096644.1
Uncharacterized protein
chr3_-_101232019 0.23 ENST00000394095.2
ENST00000394091.1
ENST00000394094.2
ENST00000358203.3
ENST00000348610.3
ENST00000314261.7
SENP7
SUMO1/sentrin specific peptidase 7
chr1_+_150039877 0.22 ENST00000419023.1
VPS45
vacuolar protein sorting 45 homolog (S. cerevisiae)
chr3_+_112280857 0.22 ENST00000492406.1
ENST00000468642.1
SLC35A5
solute carrier family 35, member A5
chr12_+_62654155 0.22 ENST00000312635.6
ENST00000393654.3
ENST00000549237.1
USP15
ubiquitin specific peptidase 15
chr7_-_97501469 0.22 ENST00000414884.1
ENST00000442734.1
ASNS
asparagine synthetase (glutamine-hydrolyzing)
chr15_-_81195510 0.22 ENST00000561295.1
RP11-351M8.1
Uncharacterized protein
chr10_-_75255668 0.22 ENST00000545874.1
PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr12_+_86268065 0.22 ENST00000551529.1
ENST00000256010.6
NTS
neurotensin
chr4_-_83483094 0.21 ENST00000508701.1
ENST00000454948.3
TMEM150C
transmembrane protein 150C
chr11_-_8954491 0.21 ENST00000526227.1
ENST00000525780.1
ENST00000326053.5
C11orf16
chromosome 11 open reading frame 16
chr6_-_18249971 0.21 ENST00000507591.1
DEK
DEK oncogene
chr14_+_21492331 0.20 ENST00000533984.1
ENST00000532213.2
AL161668.5
AL161668.5
chr2_+_58134756 0.20 ENST00000435505.2
ENST00000417641.2
VRK2
vaccinia related kinase 2
chr12_-_25348007 0.20 ENST00000354189.5
ENST00000545133.1
ENST00000554347.1
ENST00000395987.3
ENST00000320267.9
ENST00000395990.2
ENST00000537577.1
CASC1
cancer susceptibility candidate 1
chr3_-_142166796 0.20 ENST00000392981.2
XRN1
5'-3' exoribonuclease 1
chr9_-_80645520 0.20 ENST00000411677.1
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr7_+_66800928 0.20 ENST00000430244.1
RP11-166O4.5
RP11-166O4.5
chr17_+_74734052 0.19 ENST00000590514.1
MFSD11
major facilitator superfamily domain containing 11
chr17_-_66287257 0.19 ENST00000327268.4
SLC16A6
solute carrier family 16, member 6
chr12_-_76461249 0.18 ENST00000551524.1
NAP1L1
nucleosome assembly protein 1-like 1
chr3_+_63897605 0.18 ENST00000487717.1
ATXN7
ataxin 7
chr3_-_142166904 0.18 ENST00000264951.4
XRN1
5'-3' exoribonuclease 1
chr5_+_157170703 0.17 ENST00000286307.5
LSM11
LSM11, U7 small nuclear RNA associated
chr2_+_29353520 0.17 ENST00000438819.1
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr19_-_36643329 0.17 ENST00000589154.1
COX7A1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr3_-_142166846 0.17 ENST00000463916.1
ENST00000544157.1
XRN1
5'-3' exoribonuclease 1
chr1_-_241799232 0.17 ENST00000366553.1
CHML
choroideremia-like (Rab escort protein 2)
chr9_-_100459639 0.17 ENST00000375128.4
XPA
xeroderma pigmentosum, complementation group A
chr7_-_50628745 0.16 ENST00000380984.4
ENST00000357936.5
ENST00000426377.1
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr5_-_94620239 0.16 ENST00000515393.1
MCTP1
multiple C2 domains, transmembrane 1
chr8_-_128960591 0.16 ENST00000539634.1
TMEM75
transmembrane protein 75
chr11_-_111781554 0.16 ENST00000526167.1
ENST00000528961.1
CRYAB
crystallin, alpha B
chr14_+_90864504 0.16 ENST00000544280.2
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr1_+_231114795 0.16 ENST00000310256.2
ENST00000366658.2
ENST00000450711.1
ENST00000435927.1
ARV1
ARV1 homolog (S. cerevisiae)
chr3_-_52719912 0.16 ENST00000420148.1
PBRM1
polybromo 1
chr9_+_125273081 0.16 ENST00000335302.5
OR1J2
olfactory receptor, family 1, subfamily J, member 2
chr4_-_16228120 0.16 ENST00000405303.2
TAPT1
transmembrane anterior posterior transformation 1
chr6_-_79787902 0.16 ENST00000275034.4
PHIP
pleckstrin homology domain interacting protein
chr1_-_150669500 0.16 ENST00000271732.3
GOLPH3L
golgi phosphoprotein 3-like
chr3_+_122920767 0.16 ENST00000492595.1
ENST00000473494.2
ENST00000481965.2
SEC22A
SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
chr5_+_139505520 0.16 ENST00000333305.3
IGIP
IgA-inducing protein
chr5_+_72143988 0.15 ENST00000506351.2
TNPO1
transportin 1
chr4_+_55095428 0.15 ENST00000508170.1
ENST00000512143.1
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr6_+_155334780 0.15 ENST00000538270.1
ENST00000535231.1
TIAM2
T-cell lymphoma invasion and metastasis 2
chr6_+_119215308 0.15 ENST00000229595.5
ASF1A
anti-silencing function 1A histone chaperone
chr18_-_54305658 0.15 ENST00000586262.1
ENST00000217515.6
TXNL1
thioredoxin-like 1
chrX_+_155110956 0.15 ENST00000286448.6
ENST00000262640.6
ENST00000460621.1
VAMP7
vesicle-associated membrane protein 7
chr3_-_57530051 0.15 ENST00000311202.6
ENST00000351747.2
ENST00000495027.1
ENST00000389536.4
DNAH12
dynein, axonemal, heavy chain 12
chr3_+_169491171 0.14 ENST00000356716.4
MYNN
myoneurin
chr8_+_99076750 0.14 ENST00000545282.1
C8orf47
chromosome 8 open reading frame 47
chr3_-_52719888 0.14 ENST00000458294.1
PBRM1
polybromo 1
chr19_-_38085633 0.14 ENST00000593133.1
ENST00000590751.1
ENST00000358744.3
ENST00000328550.2
ENST00000451802.2
ZNF571
zinc finger protein 571
chr12_+_19593515 0.14 ENST00000360995.4
AEBP2
AE binding protein 2
chr4_-_89205879 0.14 ENST00000608933.1
ENST00000315194.4
ENST00000514204.1
PPM1K
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr21_+_25801041 0.14 ENST00000453784.2
ENST00000423581.1
AP000476.1
AP000476.1
chr17_-_39341594 0.14 ENST00000398472.1
KRTAP4-1
keratin associated protein 4-1
chr5_+_40841410 0.14 ENST00000381677.3
CARD6
caspase recruitment domain family, member 6
chr3_+_160473343 0.14 ENST00000497343.1
PPM1L
protein phosphatase, Mg2+/Mn2+ dependent, 1L
chr13_+_41885341 0.14 ENST00000379406.3
ENST00000379367.3
ENST00000403412.3
NAA16
N(alpha)-acetyltransferase 16, NatA auxiliary subunit
chr12_+_40618873 0.14 ENST00000298910.7
LRRK2
leucine-rich repeat kinase 2
chr2_+_223916862 0.14 ENST00000604125.1
KCNE4
potassium voltage-gated channel, Isk-related family, member 4
chr18_-_73967160 0.14 ENST00000579714.1
RP11-94B19.7
RP11-94B19.7
chr10_+_94352956 0.14 ENST00000260731.3
KIF11
kinesin family member 11
chr2_-_201936302 0.14 ENST00000453765.1
ENST00000452799.1
ENST00000446678.1
ENST00000418596.3
FAM126B
family with sequence similarity 126, member B
chr4_+_52709229 0.13 ENST00000334635.5
ENST00000381441.3
ENST00000381437.4
DCUN1D4
DCN1, defective in cullin neddylation 1, domain containing 4
chrX_+_133930798 0.13 ENST00000414371.2
FAM122C
family with sequence similarity 122C
chr7_-_156685841 0.13 ENST00000354505.4
ENST00000540390.1
LMBR1
limb development membrane protein 1
chr2_-_201729284 0.13 ENST00000434813.2
CLK1
CDC-like kinase 1
chr4_-_105416039 0.13 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr3_-_185641681 0.13 ENST00000259043.7
TRA2B
transformer 2 beta homolog (Drosophila)
chr16_+_2880254 0.13 ENST00000570670.1
ZG16B
zymogen granule protein 16B
chr13_-_96329048 0.13 ENST00000606011.1
ENST00000499499.2
DNAJC3-AS1
DNAJC3 antisense RNA 1 (head to head)
chr11_+_60552797 0.13 ENST00000308287.1
MS4A10
membrane-spanning 4-domains, subfamily A, member 10
chr15_+_93426514 0.13 ENST00000556722.1
CHD2
chromodomain helicase DNA binding protein 2
chr8_+_38244638 0.12 ENST00000526356.1
LETM2
leucine zipper-EF-hand containing transmembrane protein 2
chrX_-_134429952 0.12 ENST00000370764.1
ZNF75D
zinc finger protein 75D
chr1_-_204436344 0.12 ENST00000367184.2
PIK3C2B
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr1_+_150039787 0.12 ENST00000535106.1
VPS45
vacuolar protein sorting 45 homolog (S. cerevisiae)
chr15_-_70994612 0.12 ENST00000558758.1
ENST00000379983.2
ENST00000560441.1
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr4_+_146402843 0.12 ENST00000514831.1
SMAD1
SMAD family member 1
chrX_+_67718863 0.12 ENST00000374622.2
YIPF6
Yip1 domain family, member 6
chr6_-_127663543 0.12 ENST00000531582.1
ECHDC1
enoyl CoA hydratase domain containing 1
chr1_+_6615241 0.12 ENST00000333172.6
ENST00000328191.4
ENST00000351136.3
TAS1R1
taste receptor, type 1, member 1
chr11_-_111781454 0.12 ENST00000533280.1
CRYAB
crystallin, alpha B
chr4_-_16228083 0.12 ENST00000399920.3
TAPT1
transmembrane anterior posterior transformation 1
chr8_-_67090825 0.12 ENST00000276571.3
CRH
corticotropin releasing hormone
chr13_+_96329381 0.12 ENST00000602402.1
ENST00000376795.6
DNAJC3
DnaJ (Hsp40) homolog, subfamily C, member 3
chr14_+_73563735 0.12 ENST00000532192.1
RBM25
RNA binding motif protein 25
chr1_-_220445757 0.11 ENST00000358951.2
RAB3GAP2
RAB3 GTPase activating protein subunit 2 (non-catalytic)
chr3_+_186692745 0.11 ENST00000438590.1
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr1_-_33168336 0.11 ENST00000373484.3
SYNC
syncoilin, intermediate filament protein
chr8_+_31497271 0.11 ENST00000520407.1
NRG1
neuregulin 1
chr1_+_111889212 0.11 ENST00000369737.4
PIFO
primary cilia formation
chr5_+_141348598 0.11 ENST00000394520.2
ENST00000347642.3
RNF14
ring finger protein 14
chr1_+_228395755 0.11 ENST00000284548.11
ENST00000570156.2
ENST00000422127.1
ENST00000366707.4
ENST00000366709.4
OBSCN
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr10_+_60028818 0.11 ENST00000333926.5
CISD1
CDGSH iron sulfur domain 1
chr15_+_42841008 0.11 ENST00000260372.3
ENST00000568876.1
ENST00000568846.2
ENST00000562398.1
HAUS2
HAUS augmin-like complex, subunit 2
chr15_-_66084621 0.11 ENST00000564674.1
DENND4A
DENN/MADD domain containing 4A
chr10_+_99349450 0.11 ENST00000370640.3
C10orf62
chromosome 10 open reading frame 62
chr13_+_78109804 0.11 ENST00000535157.1
SCEL
sciellin
chr13_+_33160553 0.11 ENST00000315596.10
PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr3_+_188817891 0.11 ENST00000412373.1
TPRG1
tumor protein p63 regulated 1
chr7_-_94285472 0.11 ENST00000437425.2
ENST00000447873.1
ENST00000415788.2
SGCE
sarcoglycan, epsilon
chr2_-_201729393 0.11 ENST00000321356.4
CLK1
CDC-like kinase 1
chr1_+_161691353 0.11 ENST00000367948.2
FCRLB
Fc receptor-like B
chr15_+_75335604 0.10 ENST00000563393.1
PPCDC
phosphopantothenoylcysteine decarboxylase
chr9_-_35812236 0.10 ENST00000340291.2
SPAG8
sperm associated antigen 8
chr3_-_3221358 0.10 ENST00000424814.1
ENST00000450014.1
ENST00000231948.4
ENST00000432408.2
CRBN
cereblon
chr17_-_57232596 0.10 ENST00000581068.1
ENST00000330137.7
SKA2
spindle and kinetochore associated complex subunit 2
chr17_-_57232525 0.10 ENST00000583380.1
ENST00000580541.1
ENST00000578105.1
ENST00000437036.2
SKA2
spindle and kinetochore associated complex subunit 2
chr2_-_228579305 0.10 ENST00000456524.1
SLC19A3
solute carrier family 19 (thiamine transporter), member 3
chr5_+_32788945 0.10 ENST00000326958.1
AC026703.1
AC026703.1
chr7_+_23637118 0.10 ENST00000448353.1
CCDC126
coiled-coil domain containing 126
chr9_+_17134980 0.10 ENST00000380647.3
CNTLN
centlein, centrosomal protein
chrM_+_5824 0.10 ENST00000361624.2
MT-CO1
mitochondrially encoded cytochrome c oxidase I
chr16_+_50776021 0.10 ENST00000566679.2
ENST00000564634.1
ENST00000398568.2
CYLD
cylindromatosis (turban tumor syndrome)
chr1_-_150979333 0.10 ENST00000312210.5
FAM63A
family with sequence similarity 63, member A
chr10_-_124768300 0.10 ENST00000368886.5
IKZF5
IKAROS family zinc finger 5 (Pegasus)
chr12_+_62654119 0.10 ENST00000353364.3
ENST00000549523.1
ENST00000280377.5
USP15
ubiquitin specific peptidase 15
chr12_-_4647606 0.09 ENST00000261250.3
ENST00000541014.1
ENST00000545746.1
ENST00000542080.1
C12orf4
chromosome 12 open reading frame 4
chr9_+_17135016 0.09 ENST00000425824.1
ENST00000262360.5
ENST00000380641.4
CNTLN
centlein, centrosomal protein
chr4_+_186990298 0.09 ENST00000296795.3
ENST00000513189.1
TLR3
toll-like receptor 3
chr2_+_27505260 0.09 ENST00000380075.2
ENST00000296098.4
TRIM54
tripartite motif containing 54
chr4_-_175443788 0.09 ENST00000541923.1
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr3_-_123168551 0.09 ENST00000462833.1
ADCY5
adenylate cyclase 5
chr8_+_26240414 0.09 ENST00000380629.2
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr6_+_109416684 0.09 ENST00000521522.1
ENST00000524064.1
ENST00000522608.1
ENST00000521503.1
ENST00000519407.1
ENST00000519095.1
ENST00000368968.2
ENST00000522490.1
ENST00000523209.1
ENST00000368970.2
ENST00000520883.1
ENST00000523787.1
CEP57L1
centrosomal protein 57kDa-like 1
chr16_+_53088885 0.09 ENST00000566029.1
ENST00000447540.1
CHD9
chromodomain helicase DNA binding protein 9
chr17_-_34122596 0.09 ENST00000250144.8
MMP28
matrix metallopeptidase 28
chr20_-_50418972 0.09 ENST00000395997.3
SALL4
spalt-like transcription factor 4
chr14_+_31494841 0.09 ENST00000556232.1
ENST00000216366.4
ENST00000334725.4
ENST00000554609.1
ENST00000554345.1
AP4S1
adaptor-related protein complex 4, sigma 1 subunit
chr2_-_71454185 0.09 ENST00000244221.8
PAIP2B
poly(A) binding protein interacting protein 2B
chr5_+_133984462 0.09 ENST00000398844.2
ENST00000322887.4
SEC24A
SEC24 family member A
chr1_+_22379179 0.09 ENST00000315554.8
ENST00000421089.2
CDC42
cell division cycle 42
chr1_+_240177627 0.09 ENST00000447095.1
FMN2
formin 2
chr7_-_94285402 0.09 ENST00000428696.2
ENST00000445866.2
SGCE
sarcoglycan, epsilon
chr8_+_94929077 0.09 ENST00000297598.4
ENST00000520614.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr1_+_100111580 0.09 ENST00000605497.1
PALMD
palmdelphin
chr7_-_94285511 0.09 ENST00000265735.7
SGCE
sarcoglycan, epsilon
chr6_+_17600576 0.09 ENST00000259963.3
FAM8A1
family with sequence similarity 8, member A1
chr8_+_38243721 0.09 ENST00000527334.1
LETM2
leucine zipper-EF-hand containing transmembrane protein 2
chr6_+_83777374 0.08 ENST00000349129.2
ENST00000237163.5
ENST00000536812.1
DOPEY1
dopey family member 1
chr1_-_247275719 0.08 ENST00000408893.2
C1orf229
chromosome 1 open reading frame 229
chr7_-_100493482 0.08 ENST00000411582.1
ENST00000419336.2
ENST00000241069.5
ENST00000302913.4
ACHE
acetylcholinesterase (Yt blood group)
chr5_-_159797627 0.08 ENST00000393975.3
C1QTNF2
C1q and tumor necrosis factor related protein 2
chr3_-_180707466 0.08 ENST00000491873.1
ENST00000486355.1
ENST00000382564.2
DNAJC19
DnaJ (Hsp40) homolog, subfamily C, member 19
chr10_-_21806759 0.08 ENST00000444772.3
SKIDA1
SKI/DACH domain containing 1
chr1_+_186798073 0.08 ENST00000367466.3
ENST00000442353.2
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr10_+_24528108 0.08 ENST00000438429.1
KIAA1217
KIAA1217
chr14_-_65569244 0.08 ENST00000557277.1
ENST00000556892.1
MAX
MYC associated factor X
chr13_-_48575376 0.08 ENST00000434484.1
SUCLA2
succinate-CoA ligase, ADP-forming, beta subunit
chr3_+_156807663 0.08 ENST00000467995.1
ENST00000474477.1
ENST00000471719.1
LINC00881
long intergenic non-protein coding RNA 881
chr15_-_66084428 0.08 ENST00000443035.3
ENST00000431932.2
DENND4A
DENN/MADD domain containing 4A
chr11_-_111781610 0.08 ENST00000525823.1
CRYAB
crystallin, alpha B
chr16_+_31366455 0.08 ENST00000268296.4
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr13_+_50589390 0.08 ENST00000360473.4
ENST00000312942.1
KCNRG
potassium channel regulator
chr12_+_49687425 0.08 ENST00000257860.4
PRPH
peripherin
chr3_+_69788576 0.08 ENST00000352241.4
ENST00000448226.2
MITF
microphthalmia-associated transcription factor
chr14_-_24732368 0.08 ENST00000544573.1
TGM1
transglutaminase 1
chr6_+_24775153 0.08 ENST00000356509.3
ENST00000230056.3
GMNN
geminin, DNA replication inhibitor
chr1_-_247335269 0.08 ENST00000543802.2
ENST00000491356.1
ENST00000472531.1
ENST00000340684.6
ZNF124
zinc finger protein 124
chr4_+_128886584 0.08 ENST00000513371.1
C4orf29
chromosome 4 open reading frame 29
chr12_-_109027643 0.08 ENST00000388962.3
ENST00000550948.1
SELPLG
selectin P ligand
chr14_-_24732403 0.08 ENST00000206765.6
TGM1
transglutaminase 1
chr2_-_73460334 0.08 ENST00000258083.2
PRADC1
protease-associated domain containing 1
chr22_+_41347363 0.08 ENST00000216225.8
RBX1
ring-box 1, E3 ubiquitin protein ligase
chr1_+_166808692 0.08 ENST00000367876.4
POGK
pogo transposable element with KRAB domain
chr12_+_59989918 0.08 ENST00000547379.1
ENST00000549465.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr17_+_61571746 0.08 ENST00000579409.1
ACE
angiotensin I converting enzyme
chr12_+_40618764 0.08 ENST00000343742.2
LRRK2
leucine-rich repeat kinase 2
chr1_+_111888890 0.08 ENST00000369738.4
PIFO
primary cilia formation
chr12_-_39837192 0.07 ENST00000361961.3
ENST00000395670.3
KIF21A
kinesin family member 21A
chr5_-_130868688 0.07 ENST00000504575.1
ENST00000513227.1
RAPGEF6
Rap guanine nucleotide exchange factor (GEF) 6

Network of associatons between targets according to the STRING database.

First level regulatory network of TGIF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0044771 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 0.5 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.1 0.4 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.2 GO:1902823 negative regulation of late endosome to lysosome transport(GO:1902823) regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.1 0.2 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) isoquinoline alkaloid metabolic process(GO:0033076)
0.0 0.2 GO:0042322 negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
0.0 0.1 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.0 0.4 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.1 GO:1903371 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.2 GO:0070981 L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
0.0 0.4 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.1 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.3 GO:0042262 DNA protection(GO:0042262)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.0 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.0 0.1 GO:0002636 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.0 0.1 GO:0034343 microglial cell activation involved in immune response(GO:0002282) type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.3 GO:1903012 positive regulation of bone development(GO:1903012)
0.0 0.2 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0 0.1 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.0 0.1 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.0 0.1 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.2 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0036309 protein localization to M-band(GO:0036309)
0.0 0.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.2 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.1 GO:0070417 cellular response to cold(GO:0070417)
0.0 0.2 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.1 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.1 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.0 0.1 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.0 GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.0 0.0 GO:0008052 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
0.0 0.1 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0090135 positive regulation of synapse structural plasticity(GO:0051835) actin filament branching(GO:0090135)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.0 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) beta-alanine metabolic process(GO:0019482) thymine metabolic process(GO:0019859) uracil metabolic process(GO:0019860)
0.0 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.1 GO:0045213 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129) neurotransmitter receptor metabolic process(GO:0045213)
0.0 0.1 GO:0050777 negative regulation of immune response(GO:0050777)
0.0 0.2 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.2 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0 0.3 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0 0.2 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0035101 FACT complex(GO:0035101)
0.1 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.2 GO:0044753 amphisome(GO:0044753)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.4 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.2 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1 0.3 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.1 0.2 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.1 0.5 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.2 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.3 GO:0030613 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.0 0.5 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.1 GO:0005018 platelet-derived growth factor alpha-receptor activity(GO:0005018)
0.0 0.2 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.0 0.1 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.0 0.1 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.1 GO:0038131 neuregulin receptor activity(GO:0038131)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.1 GO:0031768 growth hormone-releasing hormone activity(GO:0016608) ghrelin receptor binding(GO:0031768)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.3 GO:0031432 titin binding(GO:0031432)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.1 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor