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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TLX2

Z-value: 1.45

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Transcription factors associated with TLX2

Gene Symbol Gene ID Gene Info
TLX2
ENSG00000115297.9 T cell leukemia homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TLX2hg19_v2_chr2_+_74741569_74741620-0.621.9e-01Click!

Activity profile of TLX2 motif

Sorted Z-values of TLX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_948803 2.15 ENST00000379389.4
ISG15
ISG15 ubiquitin-like modifier
chr20_+_52824367 1.18 ENST00000371419.2
PFDN4
prefoldin subunit 4
chr3_-_122283079 1.16 ENST00000471785.1
ENST00000466126.1
PARP9
poly (ADP-ribose) polymerase family, member 9
chr3_-_122283100 1.13 ENST00000492382.1
ENST00000462315.1
PARP9
poly (ADP-ribose) polymerase family, member 9
chr12_-_89918982 1.12 ENST00000549504.1
POC1B
POC1 centriolar protein B
chr1_-_1850697 1.11 ENST00000378598.4
ENST00000416272.1
ENST00000310991.3
TMEM52
transmembrane protein 52
chr1_-_92764523 1.09 ENST00000370360.3
ENST00000534881.1
GLMN
glomulin, FKBP associated protein
chr7_-_120497178 1.00 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
TSPAN12
tetraspanin 12
chr9_-_80645520 0.92 ENST00000411677.1
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr7_+_130794878 0.91 ENST00000416992.2
MKLN1
muskelin 1, intracellular mediator containing kelch motifs
chr13_+_60971427 0.91 ENST00000535286.1
ENST00000377881.2
TDRD3
tudor domain containing 3
chr7_+_89783689 0.90 ENST00000297205.2
STEAP1
six transmembrane epithelial antigen of the prostate 1
chr1_-_74663825 0.83 ENST00000370911.3
ENST00000370909.2
ENST00000354431.4
LRRIQ3
leucine-rich repeats and IQ motif containing 3
chr15_+_82555169 0.83 ENST00000565432.1
ENST00000427381.2
FAM154B
family with sequence similarity 154, member B
chr1_+_74663994 0.79 ENST00000472069.1
FPGT
fucose-1-phosphate guanylyltransferase
chr14_-_54955721 0.78 ENST00000554908.1
GMFB
glia maturation factor, beta
chr15_-_34502278 0.77 ENST00000559515.1
ENST00000256544.3
ENST00000560108.1
ENST00000559462.1
KATNBL1
katanin p80 subunit B-like 1
chr7_-_33080506 0.76 ENST00000381626.2
ENST00000409467.1
ENST00000449201.1
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr15_+_82555125 0.74 ENST00000566205.1
ENST00000339465.5
ENST00000569120.1
ENST00000566861.1
FAM154B
family with sequence similarity 154, member B
chrX_-_45629661 0.72 ENST00000602507.1
ENST00000602461.1
RP6-99M1.2
RP6-99M1.2
chr15_-_34502197 0.70 ENST00000557877.1
KATNBL1
katanin p80 subunit B-like 1
chr13_+_60971080 0.70 ENST00000377894.2
TDRD3
tudor domain containing 3
chr3_-_149051194 0.67 ENST00000470080.1
TM4SF18
transmembrane 4 L six family member 18
chr3_+_122283064 0.65 ENST00000296161.4
DTX3L
deltex 3-like (Drosophila)
chr3_-_182880541 0.62 ENST00000470251.1
ENST00000265598.3
LAMP3
lysosomal-associated membrane protein 3
chr12_+_41221975 0.62 ENST00000552913.1
CNTN1
contactin 1
chr2_+_187371440 0.61 ENST00000445547.1
ZC3H15
zinc finger CCCH-type containing 15
chr6_+_24775641 0.59 ENST00000378054.2
ENST00000476555.1
GMNN
geminin, DNA replication inhibitor
chr5_+_40841410 0.59 ENST00000381677.3
CARD6
caspase recruitment domain family, member 6
chr6_+_111303218 0.57 ENST00000441448.2
RPF2
ribosome production factor 2 homolog (S. cerevisiae)
chr5_-_102455801 0.57 ENST00000508629.1
ENST00000399004.2
GIN1
gypsy retrotransposon integrase 1
chr4_-_105416039 0.57 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr3_-_107809816 0.57 ENST00000361309.5
ENST00000355354.7
CD47
CD47 molecule
chr3_-_149051444 0.56 ENST00000296059.2
TM4SF18
transmembrane 4 L six family member 18
chr14_-_54955376 0.56 ENST00000553333.1
GMFB
glia maturation factor, beta
chr8_-_55014336 0.54 ENST00000343231.6
LYPLA1
lysophospholipase I
chr4_-_147443043 0.54 ENST00000394059.4
ENST00000502607.1
ENST00000335472.7
ENST00000432059.2
ENST00000394062.3
SLC10A7
solute carrier family 10, member 7
chr5_+_102455968 0.53 ENST00000358359.3
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr21_+_30671189 0.53 ENST00000286800.3
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr8_-_91657740 0.52 ENST00000422900.1
TMEM64
transmembrane protein 64
chrX_-_73511908 0.52 ENST00000455395.1
FTX
FTX transcript, XIST regulator (non-protein coding)
chr10_+_35416223 0.52 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM
cAMP responsive element modulator
chr12_-_27091183 0.51 ENST00000544548.1
ENST00000261191.7
ENST00000537336.1
ASUN
asunder spermatogenesis regulator
chr7_+_130794846 0.51 ENST00000421797.2
MKLN1
muskelin 1, intracellular mediator containing kelch motifs
chr11_-_102323740 0.51 ENST00000398136.2
TMEM123
transmembrane protein 123
chr13_-_88323514 0.51 ENST00000441617.1
MIR4500HG
MIR4500 host gene (non-protein coding)
chr20_+_2795626 0.51 ENST00000603872.1
ENST00000380589.4
C20orf141
chromosome 20 open reading frame 141
chr5_+_131409476 0.50 ENST00000296871.2
CSF2
colony stimulating factor 2 (granulocyte-macrophage)
chr21_+_30671690 0.50 ENST00000399921.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr8_+_86376081 0.50 ENST00000285379.5
CA2
carbonic anhydrase II
chr2_+_169659121 0.50 ENST00000397206.2
ENST00000397209.2
ENST00000421711.2
NOSTRIN
nitric oxide synthase trafficking
chr1_+_153330322 0.50 ENST00000368738.3
S100A9
S100 calcium binding protein A9
chr20_-_13765526 0.50 ENST00000202816.1
ESF1
ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
chr1_-_222885770 0.50 ENST00000355727.2
ENST00000340020.6
AIDA
axin interactor, dorsalization associated
chr4_+_140222609 0.49 ENST00000296543.5
ENST00000398947.1
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr12_-_90024360 0.49 ENST00000393164.2
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr21_-_16437126 0.49 ENST00000318948.4
NRIP1
nuclear receptor interacting protein 1
chr6_-_46620522 0.49 ENST00000275016.2
CYP39A1
cytochrome P450, family 39, subfamily A, polypeptide 1
chr10_+_35416090 0.49 ENST00000354759.3
CREM
cAMP responsive element modulator
chr6_-_6007200 0.49 ENST00000244766.2
NRN1
neuritin 1
chr4_-_147442817 0.48 ENST00000507030.1
SLC10A7
solute carrier family 10, member 7
chr11_-_22851367 0.48 ENST00000354193.4
SVIP
small VCP/p97-interacting protein
chr8_+_38758737 0.48 ENST00000521746.1
ENST00000420274.1
PLEKHA2
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
chr4_-_68411275 0.48 ENST00000273853.6
CENPC
centromere protein C
chr9_+_139847347 0.47 ENST00000371632.3
LCN12
lipocalin 12
chr2_+_160568978 0.47 ENST00000409175.1
ENST00000539065.1
ENST00000259050.4
ENST00000421037.1
MARCH7
membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
chr12_-_99038732 0.47 ENST00000393042.3
ENST00000420861.1
ENST00000299157.4
ENST00000342502.2
IKBIP
IKBKB interacting protein
chr10_-_27529779 0.47 ENST00000426079.1
ACBD5
acyl-CoA binding domain containing 5
chr12_+_9144626 0.46 ENST00000543895.1
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr1_+_222886694 0.46 ENST00000426638.1
ENST00000537020.1
ENST00000539697.1
BROX
BRO1 domain and CAAX motif containing
chrX_-_77395186 0.46 ENST00000341864.5
TAF9B
TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
chr7_-_22539771 0.45 ENST00000406890.2
ENST00000424363.1
STEAP1B
STEAP family member 1B
chr11_-_102323489 0.45 ENST00000361236.3
TMEM123
transmembrane protein 123
chr6_-_138428613 0.45 ENST00000421351.3
PERP
PERP, TP53 apoptosis effector
chr9_-_125675576 0.45 ENST00000373659.3
ZBTB6
zinc finger and BTB domain containing 6
chr11_-_93474645 0.44 ENST00000532455.1
TAF1D
TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
chr8_+_74903580 0.44 ENST00000284818.2
ENST00000518893.1
LY96
lymphocyte antigen 96
chr1_+_231114795 0.44 ENST00000310256.2
ENST00000366658.2
ENST00000450711.1
ENST00000435927.1
ARV1
ARV1 homolog (S. cerevisiae)
chr11_-_34937858 0.44 ENST00000278359.5
APIP
APAF1 interacting protein
chr12_-_89919220 0.44 ENST00000549035.1
ENST00000393179.4
POC1B
POC1 centriolar protein B
chr4_+_17812525 0.44 ENST00000251496.2
NCAPG
non-SMC condensin I complex, subunit G
chr4_+_39046615 0.43 ENST00000261425.3
ENST00000508137.2
KLHL5
kelch-like family member 5
chr9_-_80646374 0.43 ENST00000286548.4
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr4_-_165305086 0.43 ENST00000507270.1
ENST00000514618.1
ENST00000503008.1
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr2_-_224702201 0.42 ENST00000446015.2
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr8_-_27630102 0.42 ENST00000356537.4
ENST00000522915.1
ENST00000539095.1
CCDC25
coiled-coil domain containing 25
chr1_-_222886526 0.42 ENST00000541237.1
AIDA
axin interactor, dorsalization associated
chr5_+_93954358 0.42 ENST00000504099.1
ANKRD32
ankyrin repeat domain 32
chrX_+_49644470 0.41 ENST00000508866.2
USP27X
ubiquitin specific peptidase 27, X-linked
chr20_+_2795609 0.41 ENST00000554164.1
ENST00000380593.4
TMEM239
TMEM239
transmembrane protein 239
CDNA FLJ26142 fis, clone TST04526; Transmembrane protein 239; Uncharacterized protein
chr9_+_86595626 0.41 ENST00000445877.1
ENST00000325875.3
RMI1
RecQ mediated genome instability 1
chr1_+_222885884 0.41 ENST00000340934.5
BROX
BRO1 domain and CAAX motif containing
chrX_-_151999269 0.40 ENST00000370277.3
CETN2
centrin, EF-hand protein, 2
chr20_+_5731027 0.40 ENST00000378979.4
ENST00000303142.6
C20orf196
chromosome 20 open reading frame 196
chr1_+_31769836 0.40 ENST00000344147.5
ENST00000373714.1
ENST00000546109.1
ENST00000422613.2
ZCCHC17
zinc finger, CCHC domain containing 17
chr8_-_128231299 0.40 ENST00000500112.1
CCAT1
colon cancer associated transcript 1 (non-protein coding)
chr12_-_50677255 0.39 ENST00000551691.1
ENST00000394943.3
ENST00000341247.4
LIMA1
LIM domain and actin binding 1
chr1_-_108231101 0.39 ENST00000544443.1
ENST00000415432.2
VAV3
vav 3 guanine nucleotide exchange factor
chr7_+_106809406 0.39 ENST00000468410.1
ENST00000478930.1
ENST00000464009.1
ENST00000222574.4
HBP1
HMG-box transcription factor 1
chr1_+_16083098 0.38 ENST00000496928.2
ENST00000508310.1
FBLIM1
filamin binding LIM protein 1
chr2_-_224702270 0.38 ENST00000396654.2
ENST00000396653.2
ENST00000423110.1
ENST00000443700.1
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr17_-_4889508 0.38 ENST00000574606.2
CAMTA2
calmodulin binding transcription activator 2
chr11_-_34938039 0.38 ENST00000395787.3
APIP
APAF1 interacting protein
chr1_+_199996733 0.38 ENST00000236914.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr13_-_103426081 0.38 ENST00000376022.1
ENST00000376021.4
TEX30
testis expressed 30
chr3_-_179322436 0.38 ENST00000392659.2
ENST00000476781.1
MRPL47
mitochondrial ribosomal protein L47
chr7_+_77469439 0.37 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
PHTF2
putative homeodomain transcription factor 2
chr5_+_94982558 0.37 ENST00000311364.4
ENST00000458310.1
RFESD
Rieske (Fe-S) domain containing
chr1_-_235324772 0.37 ENST00000408888.3
RBM34
RNA binding motif protein 34
chr5_-_135290651 0.36 ENST00000522943.1
ENST00000514447.2
LECT2
leukocyte cell-derived chemotaxin 2
chr2_+_172544294 0.36 ENST00000358002.6
ENST00000435234.1
ENST00000443458.1
ENST00000412370.1
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr8_-_55014415 0.36 ENST00000522007.1
ENST00000521898.1
ENST00000518546.1
ENST00000316963.3
LYPLA1
lysophospholipase I
chr20_-_1373682 0.36 ENST00000381724.3
FKBP1A
FK506 binding protein 1A, 12kDa
chr11_+_124543694 0.36 ENST00000227135.2
ENST00000532692.1
SPA17
sperm autoantigenic protein 17
chr20_+_56884752 0.36 ENST00000244040.3
RAB22A
RAB22A, member RAS oncogene family
chr3_-_64253655 0.36 ENST00000498162.1
PRICKLE2
prickle homolog 2 (Drosophila)
chr13_-_88323218 0.35 ENST00000436290.2
ENST00000453832.2
ENST00000606590.1
MIR4500HG
MIR4500 host gene (non-protein coding)
chr3_-_113160334 0.35 ENST00000393845.2
ENST00000295868.2
WDR52
WD repeat domain 52
chr3_-_179322416 0.35 ENST00000259038.2
MRPL47
mitochondrial ribosomal protein L47
chr12_-_89918522 0.35 ENST00000529983.2
GALNT4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
chr13_-_103426112 0.35 ENST00000376032.4
ENST00000376029.3
TEX30
testis expressed 30
chr3_+_148847371 0.34 ENST00000296051.2
ENST00000460120.1
HPS3
Hermansky-Pudlak syndrome 3
chr11_-_85780853 0.34 ENST00000531930.1
ENST00000528398.1
PICALM
phosphatidylinositol binding clathrin assembly protein
chr15_-_71055769 0.34 ENST00000539319.1
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr1_+_24286287 0.34 ENST00000334351.7
ENST00000374468.1
PNRC2
proline-rich nuclear receptor coactivator 2
chr9_+_72873837 0.34 ENST00000361138.5
SMC5
structural maintenance of chromosomes 5
chr7_+_99971129 0.34 ENST00000394000.2
ENST00000350573.2
PILRA
paired immunoglobin-like type 2 receptor alpha
chr9_+_35673853 0.34 ENST00000378357.4
CA9
carbonic anhydrase IX
chr3_+_108308559 0.34 ENST00000486815.1
DZIP3
DAZ interacting zinc finger protein 3
chr10_+_76871229 0.34 ENST00000372690.3
SAMD8
sterile alpha motif domain containing 8
chr10_+_111765562 0.34 ENST00000360162.3
ADD3
adducin 3 (gamma)
chr18_+_29078131 0.33 ENST00000585206.1
DSG2
desmoglein 2
chrX_-_38186811 0.33 ENST00000318842.7
RPGR
retinitis pigmentosa GTPase regulator
chr7_+_73275483 0.33 ENST00000320531.2
WBSCR28
Williams-Beuren syndrome chromosome region 28
chr2_+_231921574 0.33 ENST00000308696.6
ENST00000373635.4
ENST00000440838.1
ENST00000409643.1
PSMD1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr14_+_54863739 0.32 ENST00000541304.1
CDKN3
cyclin-dependent kinase inhibitor 3
chr19_-_44388116 0.32 ENST00000587539.1
ZNF404
zinc finger protein 404
chr19_+_840963 0.32 ENST00000234347.5
PRTN3
proteinase 3
chr14_-_36789783 0.32 ENST00000605579.1
ENST00000604336.1
ENST00000359527.7
ENST00000603139.1
ENST00000318473.7
MBIP
MAP3K12 binding inhibitory protein 1
chr5_+_93954039 0.32 ENST00000265140.5
ANKRD32
ankyrin repeat domain 32
chr18_+_29077990 0.32 ENST00000261590.8
DSG2
desmoglein 2
chr1_+_199996702 0.32 ENST00000367362.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr21_-_16437255 0.32 ENST00000400199.1
ENST00000400202.1
NRIP1
nuclear receptor interacting protein 1
chr12_+_32687221 0.32 ENST00000525053.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr2_-_190445499 0.32 ENST00000261024.2
SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr9_-_88896977 0.31 ENST00000311534.6
ISCA1
iron-sulfur cluster assembly 1
chr10_-_115933942 0.31 ENST00000369285.3
ENST00000369287.3
ENST00000369286.1
C10orf118
chromosome 10 open reading frame 118
chr6_-_127664683 0.31 ENST00000528402.1
ENST00000454591.2
ECHDC1
enoyl CoA hydratase domain containing 1
chr1_+_74663896 0.31 ENST00000370898.3
ENST00000467578.2
ENST00000370894.5
ENST00000482102.2
ENST00000609362.1
ENST00000534056.1
ENST00000557284.2
ENST00000370899.3
ENST00000370895.1
ENST00000534632.1
ENST00000370893.1
ENST00000370891.2
FPGT
FPGT-TNNI3K
TNNI3K
fucose-1-phosphate guanylyltransferase
FPGT-TNNI3K readthrough
TNNI3 interacting kinase
chr2_+_192543694 0.31 ENST00000435931.1
NABP1
nucleic acid binding protein 1
chr12_+_104324112 0.31 ENST00000299767.5
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr1_-_115124257 0.31 ENST00000369541.3
BCAS2
breast carcinoma amplified sequence 2
chr10_-_52008313 0.30 ENST00000329428.6
ENST00000395526.4
ENST00000447815.1
ASAH2
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
chr8_-_55014018 0.30 ENST00000521352.1
LYPLA1
lysophospholipase I
chr12_+_50794891 0.30 ENST00000517559.1
LARP4
La ribonucleoprotein domain family, member 4
chr1_+_92764522 0.30 ENST00000610020.1
RPAP2
RNA polymerase II associated protein 2
chr4_+_41937131 0.30 ENST00000504986.1
ENST00000508448.1
ENST00000513702.1
ENST00000325094.5
TMEM33
transmembrane protein 33
chr6_+_21666633 0.30 ENST00000606851.1
CASC15
cancer susceptibility candidate 15 (non-protein coding)
chr15_-_27018175 0.30 ENST00000311550.5
GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr20_-_14318248 0.30 ENST00000378053.3
ENST00000341420.4
FLRT3
fibronectin leucine rich transmembrane protein 3
chr10_+_76871353 0.29 ENST00000542569.1
SAMD8
sterile alpha motif domain containing 8
chr2_+_102927962 0.29 ENST00000233954.1
ENST00000393393.3
ENST00000410040.1
IL1RL1
IL18R1
interleukin 1 receptor-like 1
interleukin 18 receptor 1
chr5_-_180229791 0.29 ENST00000504671.1
ENST00000507384.1
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr22_+_50925213 0.29 ENST00000395733.3
ENST00000216075.6
ENST00000395732.3
MIOX
myo-inositol oxygenase
chr16_+_66400533 0.29 ENST00000341529.3
CDH5
cadherin 5, type 2 (vascular endothelium)
chr3_+_48507621 0.29 ENST00000456089.1
TREX1
three prime repair exonuclease 1
chr3_-_143567262 0.29 ENST00000474151.1
ENST00000316549.6
SLC9A9
solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
chr3_+_108308845 0.29 ENST00000479138.1
DZIP3
DAZ interacting zinc finger protein 3
chr19_-_22034809 0.29 ENST00000594012.1
ENST00000595461.1
ENST00000596899.1
ZNF43
zinc finger protein 43
chr1_+_53480598 0.29 ENST00000430330.2
ENST00000408941.3
ENST00000478274.2
ENST00000484100.1
ENST00000435345.2
ENST00000488965.1
SCP2
sterol carrier protein 2
chr2_+_172544182 0.29 ENST00000409197.1
ENST00000456808.1
ENST00000409317.1
ENST00000409773.1
ENST00000411953.1
ENST00000409453.1
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr15_+_42694573 0.29 ENST00000397200.4
ENST00000569827.1
CAPN3
calpain 3, (p94)
chr9_+_100395891 0.29 ENST00000375147.3
NCBP1
nuclear cap binding protein subunit 1, 80kDa
chr6_-_127664736 0.29 ENST00000368291.2
ENST00000309620.9
ENST00000454859.3
ECHDC1
enoyl CoA hydratase domain containing 1
chr8_-_105601134 0.28 ENST00000276654.5
ENST00000424843.2
LRP12
low density lipoprotein receptor-related protein 12
chr9_-_125693757 0.28 ENST00000373656.3
ZBTB26
zinc finger and BTB domain containing 26
chr18_+_56531584 0.28 ENST00000590287.1
ZNF532
zinc finger protein 532
chr3_-_43663519 0.28 ENST00000427171.1
ENST00000292246.3
ANO10
anoctamin 10
chr3_+_142315294 0.28 ENST00000464320.1
PLS1
plastin 1
chr1_+_35734562 0.28 ENST00000314607.6
ENST00000373297.2
ZMYM4
zinc finger, MYM-type 4
chr1_+_207494853 0.28 ENST00000367064.3
ENST00000367063.2
ENST00000391921.4
ENST00000367067.4
ENST00000314754.8
ENST00000367065.5
ENST00000391920.4
ENST00000367062.4
ENST00000343420.6
CD55
CD55 molecule, decay accelerating factor for complement (Cromer blood group)
chr3_-_128212016 0.28 ENST00000498200.1
ENST00000341105.2
GATA2
GATA binding protein 2
chrX_+_152783131 0.28 ENST00000349466.2
ENST00000370186.1
ATP2B3
ATPase, Ca++ transporting, plasma membrane 3
chr6_-_127664475 0.28 ENST00000474289.2
ENST00000534442.1
ENST00000368289.2
ENST00000525745.1
ENST00000430841.2
ECHDC1
enoyl CoA hydratase domain containing 1
chr12_-_95611149 0.28 ENST00000549499.1
ENST00000343958.4
ENST00000546711.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr12_+_31079652 0.27 ENST00000546076.1
ENST00000535215.1
ENST00000544427.1
ENST00000261177.9
TSPAN11
tetraspanin 11
chr19_-_37019136 0.27 ENST00000592282.1
ZNF260
zinc finger protein 260
chr5_-_133968459 0.27 ENST00000505758.1
ENST00000439578.1
ENST00000502286.1
SAR1B
SAR1 homolog B (S. cerevisiae)
chr5_+_102455853 0.27 ENST00000515845.1
ENST00000321521.9
ENST00000507921.1
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr10_-_60027642 0.26 ENST00000373935.3
IPMK
inositol polyphosphate multikinase
chr16_-_71598823 0.26 ENST00000566202.1
ZNF19
zinc finger protein 19
chr15_+_93426514 0.26 ENST00000556722.1
CHD2
chromodomain helicase DNA binding protein 2
chr10_-_73975657 0.26 ENST00000394919.1
ENST00000526751.1
ASCC1
activating signal cointegrator 1 complex subunit 1
chr17_+_42925270 0.26 ENST00000253410.2
ENST00000587021.1
HIGD1B
HIG1 hypoxia inducible domain family, member 1B
chr16_-_15982440 0.26 ENST00000575938.1
ENST00000573396.1
ENST00000573968.1
ENST00000575744.1
ENST00000573429.1
ENST00000255759.6
ENST00000575073.1
FOPNL
FGFR1OP N-terminal like
chr17_-_40134339 0.26 ENST00000587727.1
DNAJC7
DnaJ (Hsp40) homolog, subfamily C, member 7
chr14_-_23762777 0.26 ENST00000431326.2
HOMEZ
homeobox and leucine zipper encoding
chr12_+_50794730 0.26 ENST00000523389.1
ENST00000518561.1
ENST00000347328.5
ENST00000550260.1
LARP4
La ribonucleoprotein domain family, member 4
chr1_+_33005020 0.25 ENST00000373510.4
ENST00000316459.4
ZBTB8A
zinc finger and BTB domain containing 8A
chr17_+_15604513 0.25 ENST00000481540.1
ZNF286A
Homo sapiens zinc finger protein 286A (ZNF286A), transcript variant 6, mRNA.

Network of associatons between targets according to the STRING database.

First level regulatory network of TLX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0001543 ovarian follicle rupture(GO:0001543)
0.2 2.3 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.2 1.0 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.2 2.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.2 1.4 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.2 0.5 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.2 0.5 GO:0042938 dipeptide transport(GO:0042938)
0.2 1.3 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.2 0.5 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.2 0.5 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1 0.6 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.1 0.1 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.1 0.7 GO:0003165 Purkinje myocyte development(GO:0003165)
0.1 0.5 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 0.4 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.1 1.2 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 0.3 GO:1903414 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.1 1.4 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.5 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1 0.7 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.3 GO:0031247 actin rod assembly(GO:0031247)
0.1 1.2 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.5 GO:1903061 regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061)
0.1 0.4 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.1 0.3 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.1 0.8 GO:0070269 pyroptosis(GO:0070269)
0.1 0.4 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 0.8 GO:1990034 calcium ion export from cell(GO:1990034)
0.1 0.6 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.1 1.1 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.1 0.6 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.3 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.1 0.4 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.3 GO:0016598 protein arginylation(GO:0016598)
0.1 0.5 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.2 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040)
0.1 0.6 GO:0030242 pexophagy(GO:0030242)
0.1 0.1 GO:0090027 negative regulation of monocyte chemotaxis(GO:0090027)
0.1 0.3 GO:0034093 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.1 0.2 GO:0034727 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521)
0.1 0.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 1.0 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.5 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.9 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.1 0.2 GO:1990927 calcium ion regulated lysosome exocytosis(GO:1990927)
0.1 0.2 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.1 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 0.6 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.9 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.2 GO:0031081 nuclear pore distribution(GO:0031081) nuclear pore localization(GO:0051664)
0.0 0.2 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.3 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.2 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.3 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.0 0.6 GO:1902570 protein localization to nucleolus(GO:1902570)
0.0 0.3 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.0 0.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.2 GO:1903722 regulation of centriole elongation(GO:1903722)
0.0 0.2 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 1.0 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.6 GO:0015074 DNA integration(GO:0015074)
0.0 0.3 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.2 GO:0097501 stress response to metal ion(GO:0097501)
0.0 0.1 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.0 0.3 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.9 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.2 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.6 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.2 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.3 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.5 GO:0002934 desmosome organization(GO:0002934)
0.0 0.3 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 0.2 GO:0032252 secretory granule localization(GO:0032252)
0.0 0.5 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.6 GO:0008228 opsonization(GO:0008228)
0.0 1.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.0 0.1 GO:2001162 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.0 0.3 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.5 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.2 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.0 0.5 GO:0002643 regulation of tolerance induction(GO:0002643)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.3 GO:1905216 positive regulation of RNA binding(GO:1905216)
0.0 0.0 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.0 0.1 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.0 0.3 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.0 0.1 GO:0018277 protein deamination(GO:0018277)
0.0 0.2 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.3 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.1 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.0 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.6 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 1.6 GO:0001895 retina homeostasis(GO:0001895)
0.0 0.0 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 1.2 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 1.2 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.2 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.3 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0061591 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.7 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.0 0.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.5 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.0 0.1 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.2 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:1904469 positive regulation of tumor necrosis factor secretion(GO:1904469)
0.0 0.0 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.0 0.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.1 GO:0016048 detection of temperature stimulus(GO:0016048) sensory perception of temperature stimulus(GO:0050951)
0.0 0.2 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.2 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0003350 pulmonary myocardium development(GO:0003350)
0.0 0.1 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.4 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0 0.4 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.3 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.1 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.2 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.5 GO:0010390 histone monoubiquitination(GO:0010390)
0.0 0.4 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
0.0 0.1 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.4 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.3 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.1 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 0.6 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.3 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.1 GO:0045714 regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
0.0 0.2 GO:0015871 choline transport(GO:0015871)
0.0 0.4 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362) termination of RNA polymerase I transcription(GO:0006363)
0.0 0.8 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.0 GO:0010193 response to ozone(GO:0010193)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 0.4 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.1 1.2 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.3 GO:0034515 proteasome storage granule(GO:0034515)
0.1 0.3 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.4 GO:0071942 XPC complex(GO:0071942)
0.1 0.6 GO:0070876 SOSS complex(GO:0070876)
0.1 0.3 GO:0005846 nuclear cap binding complex(GO:0005846)
0.1 1.1 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462) Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.5 GO:0031415 NatA complex(GO:0031415)
0.1 1.3 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.1 0.3 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.4 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.3 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.4 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.3 GO:1990357 terminal web(GO:1990357)
0.0 0.3 GO:0000796 condensin complex(GO:0000796)
0.0 0.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.4 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 1.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.5 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 1.2 GO:0030057 desmosome(GO:0030057)
0.0 1.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.3 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.5 GO:0000124 SAGA complex(GO:0000124)
0.0 0.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.3 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 1.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 1.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.3 GO:0044447 axoneme part(GO:0044447)
0.0 0.2 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 1.5 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.1 GO:0016013 syntrophin complex(GO:0016013)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.2 1.4 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.2 1.4 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.2 0.6 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.2 2.2 GO:0031386 protein tag(GO:0031386)
0.2 1.1 GO:0070568 guanylyltransferase activity(GO:0070568)
0.2 0.8 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.1 0.6 GO:0047860 diiodophenylpyruvate reductase activity(GO:0047860)
0.1 0.4 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.1 0.3 GO:0097689 iron channel activity(GO:0097689)
0.1 0.4 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.1 0.3 GO:0070538 oleic acid binding(GO:0070538)
0.1 1.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.6 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 1.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.5 GO:0004064 arylesterase activity(GO:0004064)
0.1 0.5 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 2.3 GO:0070403 NAD+ binding(GO:0070403)
0.1 0.6 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.3 GO:0004057 arginyltransferase activity(GO:0004057)
0.1 1.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.2 GO:0019778 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.1 0.3 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.1 0.7 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 0.2 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.1 1.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 1.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.2 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.1 0.6 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 1.1 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.8 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.4 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.2 GO:0052723 inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) inositol hexakisphosphate kinase activity(GO:0000828) inositol heptakisphosphate kinase activity(GO:0000829) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.3 GO:0055103 ligase regulator activity(GO:0055103)
0.0 0.1 GO:0002113 interleukin-33 binding(GO:0002113)
0.0 0.5 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.4 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.2 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.3 GO:0046790 virion binding(GO:0046790)
0.0 0.9 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.3 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.2 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.4 GO:0032407 MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407)
0.0 0.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.3 GO:0022821 potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821)
0.0 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.2 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.8 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.5 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 1.0 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.4 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.1 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.0 0.2 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.1 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 0.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.6 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.7 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.3 GO:0008199 ferric iron binding(GO:0008199)
0.0 1.7 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.3 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.3 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 0.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.8 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.8 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.0 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.3 GO:0001671 ATPase activator activity(GO:0001671)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 2.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.4 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.3 PID S1P S1P2 PATHWAY S1P2 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.8 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.4 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 1.4 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.6 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 2.2 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.8 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.2 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.8 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.3 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.5 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions