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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TP63

Z-value: 1.05

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Transcription factors associated with TP63

Gene Symbol Gene ID Gene Info
TP63
ENSG00000073282.8 tumor protein p63

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TP63hg19_v2_chr3_+_189349162_189349305-0.768.1e-02Click!

Activity profile of TP63 motif

Sorted Z-values of TP63 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_95873257 0.79 ENST00000425953.1
AC092835.2
AC092835.2
chr1_-_46089718 0.78 ENST00000421127.2
ENST00000343901.2
ENST00000528266.1
CCDC17
coiled-coil domain containing 17
chr20_+_34679725 0.55 ENST00000432589.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr22_-_38577782 0.51 ENST00000430886.1
ENST00000332509.3
ENST00000447598.2
ENST00000435484.1
ENST00000402064.1
ENST00000436218.1
PLA2G6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr14_+_24779340 0.47 ENST00000533293.1
ENST00000543919.1
LTB4R2
leukotriene B4 receptor 2
chr16_+_57653854 0.46 ENST00000568908.1
ENST00000568909.1
ENST00000566778.1
ENST00000561988.1
GPR56
G protein-coupled receptor 56
chr16_-_67224002 0.46 ENST00000563889.1
ENST00000564418.1
ENST00000545725.2
ENST00000314586.6
EXOC3L1
exocyst complex component 3-like 1
chr16_+_32264645 0.45 ENST00000569631.1
ENST00000354614.3
TP53TG3D
TP53 target 3D
chr16_+_57653989 0.44 ENST00000567835.1
ENST00000569372.1
ENST00000563548.1
ENST00000562003.1
GPR56
G protein-coupled receptor 56
chr12_-_15114603 0.43 ENST00000228945.4
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr4_+_8321882 0.40 ENST00000509453.1
ENST00000503186.1
RP11-774O3.2
RP11-774O3.1
RP11-774O3.2
RP11-774O3.1
chr17_+_38337491 0.34 ENST00000538981.1
RAPGEFL1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr7_+_100466433 0.34 ENST00000429658.1
TRIP6
thyroid hormone receptor interactor 6
chr19_+_42364313 0.33 ENST00000601492.1
ENST00000600467.1
ENST00000221975.2
RPS19
ribosomal protein S19
chr7_+_75024903 0.32 ENST00000323819.3
ENST00000430211.1
TRIM73
tripartite motif containing 73
chr19_-_53426700 0.31 ENST00000596623.1
ZNF888
zinc finger protein 888
chr8_-_23021533 0.30 ENST00000312584.3
TNFRSF10D
tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
chr9_-_132383055 0.29 ENST00000372478.4
C9orf50
chromosome 9 open reading frame 50
chr1_-_3528034 0.29 ENST00000356575.4
MEGF6
multiple EGF-like-domains 6
chr17_+_1646130 0.29 ENST00000453066.1
ENST00000324015.3
ENST00000450523.2
ENST00000453723.1
ENST00000382061.4
SERPINF2
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr19_-_3500635 0.28 ENST00000250937.3
DOHH
deoxyhypusine hydroxylase/monooxygenase
chr17_-_14140166 0.28 ENST00000420162.2
ENST00000431716.2
CDRT15
CMT1A duplicated region transcript 15
chr20_-_43280361 0.27 ENST00000372874.4
ADA
adenosine deaminase
chr19_-_10420459 0.27 ENST00000403352.1
ENST00000403903.3
ZGLP1
zinc finger, GATA-like protein 1
chr7_-_110174754 0.26 ENST00000435466.1
AC003088.1
AC003088.1
chr4_+_2794750 0.25 ENST00000452765.2
ENST00000389838.2
SH3BP2
SH3-domain binding protein 2
chr19_+_42364460 0.25 ENST00000593863.1
RPS19
ribosomal protein S19
chr11_+_64073699 0.25 ENST00000405666.1
ENST00000468670.1
ESRRA
estrogen-related receptor alpha
chr19_+_19779589 0.25 ENST00000541458.1
ZNF101
zinc finger protein 101
chr7_+_140396946 0.24 ENST00000476470.1
ENST00000471136.1
NDUFB2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chr15_-_89456593 0.24 ENST00000558029.1
ENST00000539437.1
ENST00000542878.1
ENST00000268151.7
ENST00000566497.1
MFGE8
milk fat globule-EGF factor 8 protein
chr2_+_11752379 0.24 ENST00000396123.1
GREB1
growth regulation by estrogen in breast cancer 1
chr7_+_140396756 0.24 ENST00000460088.1
ENST00000472695.1
NDUFB2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chr15_+_74466744 0.23 ENST00000560862.1
ENST00000395118.1
ISLR
immunoglobulin superfamily containing leucine-rich repeat
chr20_+_57264187 0.23 ENST00000525967.1
ENST00000525817.1
NPEPL1
aminopeptidase-like 1
chr14_+_39703112 0.23 ENST00000555143.1
ENST00000280082.3
MIA2
melanoma inhibitory activity 2
chr5_-_64920115 0.23 ENST00000381018.3
ENST00000274327.7
TRIM23
tripartite motif containing 23
chr11_-_77899634 0.23 ENST00000526208.1
ENST00000529350.1
ENST00000530018.1
ENST00000528776.1
KCTD21
potassium channel tetramerization domain containing 21
chr11_-_1330834 0.22 ENST00000525159.1
ENST00000317204.6
ENST00000542915.1
ENST00000527938.1
ENST00000530541.1
ENST00000263646.7
TOLLIP
toll interacting protein
chr15_+_69365272 0.22 ENST00000559914.1
ENST00000558369.1
LINC00277
long intergenic non-protein coding RNA 277
chr1_+_42619070 0.22 ENST00000372581.1
GUCA2B
guanylate cyclase activator 2B (uroguanylin)
chr15_-_90233866 0.22 ENST00000561257.1
PEX11A
peroxisomal biogenesis factor 11 alpha
chr19_-_47734448 0.22 ENST00000439096.2
BBC3
BCL2 binding component 3
chr12_+_116955659 0.22 ENST00000552992.1
RP11-148B3.1
RP11-148B3.1
chr16_+_57653625 0.22 ENST00000567553.1
ENST00000565314.1
GPR56
G protein-coupled receptor 56
chr19_-_4717835 0.21 ENST00000599248.1
DPP9
dipeptidyl-peptidase 9
chr7_+_102389434 0.21 ENST00000409231.3
ENST00000418198.1
FAM185A
family with sequence similarity 185, member A
chr22_+_40573921 0.21 ENST00000454349.2
ENST00000335727.9
TNRC6B
trinucleotide repeat containing 6B
chr16_+_57653596 0.21 ENST00000568791.1
ENST00000570044.1
GPR56
G protein-coupled receptor 56
chr7_-_72439997 0.20 ENST00000285805.3
TRIM74
tripartite motif containing 74
chr1_-_3447967 0.20 ENST00000294599.4
MEGF6
multiple EGF-like-domains 6
chr6_+_31691121 0.20 ENST00000480039.1
ENST00000375810.4
ENST00000375805.2
ENST00000375809.3
ENST00000375804.2
ENST00000375814.3
ENST00000375806.2
C6orf25
chromosome 6 open reading frame 25
chr15_-_89456630 0.20 ENST00000268150.8
MFGE8
milk fat globule-EGF factor 8 protein
chr21_+_44313375 0.19 ENST00000354250.2
ENST00000340344.4
NDUFV3
NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa
chr20_+_816695 0.19 ENST00000246100.3
FAM110A
family with sequence similarity 110, member A
chr6_+_10747986 0.19 ENST00000379542.5
TMEM14B
transmembrane protein 14B
chr6_-_152957944 0.19 ENST00000423061.1
SYNE1
spectrin repeat containing, nuclear envelope 1
chr17_+_20483037 0.19 ENST00000399044.1
CDRT15L2
CMT1A duplicated region transcript 15-like 2
chr20_-_43280325 0.19 ENST00000537820.1
ADA
adenosine deaminase
chr22_+_38302285 0.19 ENST00000215957.6
MICALL1
MICAL-like 1
chr9_-_116159635 0.19 ENST00000452726.1
ALAD
aminolevulinate dehydratase
chr11_+_47608198 0.19 ENST00000356737.2
ENST00000538490.1
FAM180B
family with sequence similarity 180, member B
chr5_+_132009675 0.18 ENST00000231449.2
ENST00000350025.2
IL4
interleukin 4
chr6_-_111804905 0.18 ENST00000358835.3
ENST00000435970.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr6_+_134758827 0.18 ENST00000431422.1
LINC01010
long intergenic non-protein coding RNA 1010
chr7_+_72742178 0.18 ENST00000442793.1
ENST00000413573.2
ENST00000252037.4
FKBP6
FK506 binding protein 6, 36kDa
chr5_+_27472371 0.18 ENST00000512067.1
ENST00000510165.1
ENST00000505775.1
ENST00000514844.1
ENST00000503107.1
LINC01021
long intergenic non-protein coding RNA 1021
chr11_-_65686586 0.18 ENST00000438576.2
C11orf68
chromosome 11 open reading frame 68
chr9_+_134065519 0.18 ENST00000531600.1
NUP214
nucleoporin 214kDa
chr14_+_24779376 0.18 ENST00000530080.1
LTB4R2
leukotriene B4 receptor 2
chr4_+_186317133 0.18 ENST00000507753.1
ANKRD37
ankyrin repeat domain 37
chr16_+_1832902 0.18 ENST00000262302.9
ENST00000563136.1
ENST00000565987.1
ENST00000543305.1
ENST00000568287.1
ENST00000565134.1
NUBP2
nucleotide binding protein 2
chr17_+_42015654 0.18 ENST00000565120.1
RP11-527L4.2
Uncharacterized protein
chr5_-_42811986 0.18 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr9_+_134065506 0.18 ENST00000483497.2
NUP214
nucleoporin 214kDa
chr10_+_5726764 0.17 ENST00000328090.5
ENST00000496681.1
FAM208B
family with sequence similarity 208, member B
chr11_-_65686496 0.17 ENST00000449692.3
C11orf68
chromosome 11 open reading frame 68
chr11_+_832804 0.17 ENST00000397420.3
ENST00000525718.1
CD151
CD151 molecule (Raph blood group)
chr11_-_10920714 0.17 ENST00000533941.1
CTD-2003C8.2
CTD-2003C8.2
chr19_+_46498704 0.17 ENST00000595358.1
ENST00000594672.1
ENST00000536603.1
CCDC61
coiled-coil domain containing 61
chr10_-_88729200 0.17 ENST00000474994.2
MMRN2
multimerin 2
chrX_+_2670066 0.17 ENST00000381174.5
ENST00000419513.2
ENST00000426774.1
XG
Xg blood group
chr7_-_100287071 0.17 ENST00000275732.5
GIGYF1
GRB10 interacting GYF protein 1
chr18_+_61144160 0.17 ENST00000489441.1
ENST00000424602.1
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr11_-_111782696 0.16 ENST00000227251.3
ENST00000526180.1
CRYAB
crystallin, alpha B
chr3_+_184081137 0.16 ENST00000443489.1
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr7_+_140396465 0.16 ENST00000476279.1
ENST00000247866.4
ENST00000461457.1
ENST00000465506.1
ENST00000204307.5
ENST00000464566.1
NDUFB2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chr12_+_108956355 0.16 ENST00000535729.1
ENST00000431221.2
ENST00000547005.1
ENST00000311893.9
ENST00000392807.4
ENST00000338291.4
ENST00000539593.1
ISCU
iron-sulfur cluster assembly enzyme
chr19_-_11639931 0.16 ENST00000592312.1
ENST00000590480.1
ENST00000585318.1
ENST00000252440.7
ENST00000417981.2
ENST00000270517.7
ECSIT
ECSIT signalling integrator
chr17_-_72855989 0.16 ENST00000293190.5
GRIN2C
glutamate receptor, ionotropic, N-methyl D-aspartate 2C
chr19_+_8483272 0.16 ENST00000602117.1
MARCH2
membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
chr1_-_228603694 0.16 ENST00000366697.2
TRIM17
tripartite motif containing 17
chr3_-_9994021 0.16 ENST00000411976.2
ENST00000412055.1
PRRT3
proline-rich transmembrane protein 3
chr12_+_119616447 0.16 ENST00000281938.2
HSPB8
heat shock 22kDa protein 8
chr10_+_99344071 0.16 ENST00000370647.4
ENST00000370646.4
HOGA1
4-hydroxy-2-oxoglutarate aldolase 1
chr21_-_47613673 0.15 ENST00000594486.1
AP001468.1
Protein LOC101060037
chr9_-_136605042 0.15 ENST00000371872.4
ENST00000298628.5
ENST00000422262.2
SARDH
sarcosine dehydrogenase
chr11_-_36310958 0.15 ENST00000532705.1
ENST00000263401.5
ENST00000452374.2
COMMD9
COMM domain containing 9
chr19_+_49497121 0.15 ENST00000413176.2
RUVBL2
RuvB-like AAA ATPase 2
chr11_+_67776012 0.15 ENST00000539229.1
ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr3_-_123168551 0.14 ENST00000462833.1
ADCY5
adenylate cyclase 5
chr1_+_20959943 0.14 ENST00000321556.4
PINK1
PTEN induced putative kinase 1
chr19_-_6057282 0.14 ENST00000592281.1
RFX2
regulatory factor X, 2 (influences HLA class II expression)
chr5_+_6766004 0.14 ENST00000506093.1
RP11-332J15.3
RP11-332J15.3
chr5_+_179247759 0.14 ENST00000389805.4
ENST00000504627.1
ENST00000402874.3
ENST00000510187.1
SQSTM1
sequestosome 1
chr2_+_217524323 0.14 ENST00000456764.1
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr19_-_46288917 0.14 ENST00000537879.1
ENST00000596586.1
ENST00000595946.1
DMWD
AC011530.4
dystrophia myotonica, WD repeat containing
Uncharacterized protein
chrX_+_153029633 0.14 ENST00000538966.1
ENST00000361971.5
ENST00000538776.1
ENST00000538543.1
PLXNB3
plexin B3
chr17_-_76824975 0.14 ENST00000586066.2
USP36
ubiquitin specific peptidase 36
chr22_-_36925124 0.13 ENST00000457241.1
EIF3D
eukaryotic translation initiation factor 3, subunit D
chr19_-_47288162 0.13 ENST00000594991.1
SLC1A5
solute carrier family 1 (neutral amino acid transporter), member 5
chr5_-_156390230 0.13 ENST00000407087.3
ENST00000274532.2
TIMD4
T-cell immunoglobulin and mucin domain containing 4
chr22_-_38577731 0.13 ENST00000335539.3
PLA2G6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr2_+_112813134 0.13 ENST00000452614.1
TMEM87B
transmembrane protein 87B
chr11_-_133822111 0.13 ENST00000526663.1
IGSF9B
immunoglobulin superfamily, member 9B
chr17_+_79859985 0.13 ENST00000333383.7
NPB
neuropeptide B
chr8_+_22853345 0.13 ENST00000522948.1
RHOBTB2
Rho-related BTB domain containing 2
chr11_+_393428 0.13 ENST00000533249.1
ENST00000527442.1
PKP3
plakophilin 3
chrX_-_153602991 0.13 ENST00000369850.3
ENST00000422373.1
FLNA
filamin A, alpha
chr8_+_22960426 0.13 ENST00000540813.1
TNFRSF10C
tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
chr11_+_61891445 0.13 ENST00000394818.3
ENST00000533896.1
ENST00000278849.4
INCENP
inner centromere protein antigens 135/155kDa
chr11_+_65122216 0.13 ENST00000309880.5
TIGD3
tigger transposable element derived 3
chr8_+_145218673 0.13 ENST00000326134.5
MROH1
maestro heat-like repeat family member 1
chr11_-_104972158 0.13 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
CASP1
CARD16
CARD17
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chrX_-_45710920 0.13 ENST00000456532.1
RP5-1158E12.3
RP5-1158E12.3
chr12_-_88974236 0.12 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KITLG
KIT ligand
chr3_-_149510553 0.12 ENST00000462519.2
ENST00000446160.1
ENST00000383050.3
ANKUB1
ankyrin repeat and ubiquitin domain containing 1
chr19_-_18366182 0.12 ENST00000355502.3
PDE4C
phosphodiesterase 4C, cAMP-specific
chr17_+_75450075 0.12 ENST00000592951.1
SEPT9
septin 9
chr17_-_28661065 0.12 ENST00000328886.4
ENST00000538566.2
TMIGD1
transmembrane and immunoglobulin domain containing 1
chr17_+_75450146 0.12 ENST00000585929.1
ENST00000590917.1
SEPT9
septin 9
chr19_+_507299 0.12 ENST00000359315.5
TPGS1
tubulin polyglutamylase complex subunit 1
chr4_+_72204755 0.12 ENST00000512686.1
ENST00000340595.3
SLC4A4
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
chr16_-_32687431 0.12 ENST00000398680.3
ENST00000569420.1
TP53TG3
TP53 target 3
chr17_+_8191815 0.12 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
RANGRF
RAN guanine nucleotide release factor
chr4_-_87374330 0.12 ENST00000511328.1
ENST00000503911.1
MAPK10
mitogen-activated protein kinase 10
chr7_-_72742085 0.11 ENST00000333149.2
TRIM50
tripartite motif containing 50
chr19_-_15235906 0.11 ENST00000600984.1
ILVBL
ilvB (bacterial acetolactate synthase)-like
chr6_+_10748019 0.11 ENST00000543878.1
ENST00000461342.1
ENST00000475942.1
ENST00000379530.3
ENST00000473276.1
ENST00000481240.1
ENST00000467317.1
SYCP2L
TMEM14B
synaptonemal complex protein 2-like
transmembrane protein 14B
chr16_-_30006922 0.11 ENST00000564026.1
HIRIP3
HIRA interacting protein 3
chr4_+_3388057 0.11 ENST00000538395.1
RGS12
regulator of G-protein signaling 12
chr12_+_120031264 0.11 ENST00000426426.1
TMEM233
transmembrane protein 233
chr19_+_12305824 0.11 ENST00000415793.1
ENST00000440004.1
ENST00000426044.1
CTD-2666L21.1
CTD-2666L21.1
chr1_-_19229014 0.11 ENST00000538839.1
ENST00000290597.5
ALDH4A1
aldehyde dehydrogenase 4 family, member A1
chr3_-_191000172 0.11 ENST00000427544.2
UTS2B
urotensin 2B
chr11_-_64889252 0.11 ENST00000525297.1
ENST00000529259.1
FAU
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
chr20_+_35234223 0.11 ENST00000342422.3
C20orf24
chromosome 20 open reading frame 24
chr1_+_203256898 0.11 ENST00000433008.1
RP11-134P9.3
RP11-134P9.3
chr19_-_10613421 0.11 ENST00000393623.2
KEAP1
kelch-like ECH-associated protein 1
chr4_-_47916613 0.11 ENST00000381538.3
ENST00000329043.3
NFXL1
nuclear transcription factor, X-box binding-like 1
chr6_-_10747802 0.11 ENST00000606522.1
ENST00000606652.1
RP11-421M1.8
RP11-421M1.8
chr2_+_71127699 0.11 ENST00000234392.2
VAX2
ventral anterior homeobox 2
chr22_+_39493207 0.11 ENST00000348946.4
ENST00000442487.3
ENST00000421988.2
APOBEC3H
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H
chr22_+_45714301 0.11 ENST00000427777.1
FAM118A
family with sequence similarity 118, member A
chr19_+_4007644 0.10 ENST00000262971.2
PIAS4
protein inhibitor of activated STAT, 4
chr19_+_19779686 0.10 ENST00000415784.2
ZNF101
zinc finger protein 101
chr1_-_19229248 0.10 ENST00000375341.3
ALDH4A1
aldehyde dehydrogenase 4 family, member A1
chr10_-_101190202 0.10 ENST00000543866.1
ENST00000370508.5
GOT1
glutamic-oxaloacetic transaminase 1, soluble
chr1_+_153747746 0.10 ENST00000368661.3
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr11_+_46366918 0.10 ENST00000528615.1
ENST00000395574.3
DGKZ
diacylglycerol kinase, zeta
chr15_-_72767490 0.10 ENST00000565181.1
RP11-1007O24.3
RP11-1007O24.3
chr7_-_99869799 0.10 ENST00000436886.2
GATS
GATS, stromal antigen 3 opposite strand
chr2_-_216003127 0.10 ENST00000412081.1
ENST00000272895.7
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr2_-_31361543 0.10 ENST00000349752.5
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr6_+_32939964 0.10 ENST00000607833.1
BRD2
bromodomain containing 2
chr2_-_112614424 0.10 ENST00000427997.1
ANAPC1
anaphase promoting complex subunit 1
chr11_+_76493294 0.10 ENST00000533752.1
TSKU
tsukushi, small leucine rich proteoglycan
chr3_-_57113281 0.10 ENST00000468466.1
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr13_+_23755054 0.10 ENST00000218867.3
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr12_-_126467906 0.10 ENST00000507313.1
ENST00000545784.1
LINC00939
long intergenic non-protein coding RNA 939
chr1_+_15764931 0.10 ENST00000375949.4
ENST00000375943.2
CTRC
chymotrypsin C (caldecrin)
chr16_-_70729496 0.10 ENST00000567648.1
VAC14
Vac14 homolog (S. cerevisiae)
chr3_+_70048881 0.10 ENST00000483525.1
RP11-460N16.1
RP11-460N16.1
chr19_+_56459198 0.10 ENST00000291971.3
ENST00000590542.1
NLRP8
NLR family, pyrin domain containing 8
chr17_+_75450099 0.10 ENST00000586433.1
SEPT9
septin 9
chr6_+_106546808 0.09 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr1_+_17906970 0.09 ENST00000375415.1
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr4_-_40516560 0.09 ENST00000513473.1
RBM47
RNA binding motif protein 47
chr21_+_43823983 0.09 ENST00000291535.6
ENST00000450356.1
ENST00000319294.6
ENST00000398367.1
UBASH3A
ubiquitin associated and SH3 domain containing A
chr15_+_40532723 0.09 ENST00000558878.1
ENST00000558183.1
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr14_-_98444438 0.09 ENST00000512901.2
C14orf64
chromosome 14 open reading frame 64
chr14_-_94595993 0.09 ENST00000238609.3
IFI27L2
interferon, alpha-inducible protein 27-like 2
chr19_-_11688260 0.09 ENST00000590832.1
ACP5
acid phosphatase 5, tartrate resistant
chr12_+_49687425 0.09 ENST00000257860.4
PRPH
peripherin
chr17_+_49230897 0.09 ENST00000393196.3
ENST00000336097.3
ENST00000480143.1
ENST00000511355.1
ENST00000013034.3
ENST00000393198.3
ENST00000608447.1
ENST00000393193.2
ENST00000376392.6
ENST00000555572.1
NME1
NME1-NME2
NME2
NME/NM23 nucleoside diphosphate kinase 1
NME1-NME2 readthrough
NME/NM23 nucleoside diphosphate kinase 2
chr1_-_114447620 0.09 ENST00000369569.1
ENST00000432415.1
ENST00000369571.2
AP4B1
adaptor-related protein complex 4, beta 1 subunit
chr3_+_132316081 0.09 ENST00000249887.2
ACKR4
atypical chemokine receptor 4
chr15_-_55700522 0.09 ENST00000564092.1
ENST00000310958.6
CCPG1
cell cycle progression 1
chr2_-_45162783 0.09 ENST00000432125.2
RP11-89K21.1
RP11-89K21.1
chr10_+_75532028 0.09 ENST00000372841.3
ENST00000394790.1
FUT11
fucosyltransferase 11 (alpha (1,3) fucosyltransferase)
chr1_-_153588334 0.09 ENST00000476873.1
S100A14
S100 calcium binding protein A14
chr9_+_124088860 0.09 ENST00000373806.1
GSN
gelsolin
chr11_-_64889529 0.09 ENST00000531743.1
ENST00000527548.1
ENST00000526555.1
ENST00000279259.3
FAU
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
chr20_-_23669590 0.08 ENST00000217423.3
CST4
cystatin S
chr17_-_26695013 0.08 ENST00000555059.2
CTB-96E2.2
Homeobox protein SEBOX
chr3_-_167813672 0.08 ENST00000470487.1
GOLIM4
golgi integral membrane protein 4
chr11_+_46366799 0.08 ENST00000532868.2
DGKZ
diacylglycerol kinase, zeta
chr11_+_64950801 0.08 ENST00000526468.1
CAPN1
calpain 1, (mu/I) large subunit
chr2_-_31361362 0.08 ENST00000430167.1
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr1_+_154300217 0.08 ENST00000368489.3
ATP8B2
ATPase, aminophospholipid transporter, class I, type 8B, member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of TP63

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.2 0.5 GO:0046103 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.1 0.6 GO:0060266 positive regulation of respiratory burst involved in inflammatory response(GO:0060265) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 0.6 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.1 0.2 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.1 0.4 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.1 0.3 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.3 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 0.4 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.2 GO:0033058 directional locomotion(GO:0033058)
0.1 0.1 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
0.1 0.2 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.0 0.1 GO:1903383 neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.0 0.2 GO:0071284 cellular response to lead ion(GO:0071284)
0.0 0.2 GO:0071288 cellular response to mercury ion(GO:0071288) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.3 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.1 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.0 0.1 GO:0071733 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 0.3 GO:0044375 peroxisome membrane biogenesis(GO:0016557) regulation of peroxisome size(GO:0044375)
0.0 0.1 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.1 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.0 0.0 GO:0051604 protein maturation(GO:0051604)
0.0 0.2 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.0 0.4 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 0.1 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.5 GO:0051601 exocyst localization(GO:0051601)
0.0 0.3 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:0072684 mitochondrial tRNA 3'-trailer cleavage, endonucleolytic(GO:0072684)
0.0 0.1 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.0 0.1 GO:0045799 positive regulation of chromatin assembly or disassembly(GO:0045799)
0.0 0.2 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.1 GO:1902512 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.0 0.1 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.0 0.1 GO:0070383 DNA cytosine deamination(GO:0070383)
0.0 0.0 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.0 0.1 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.1 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.1 GO:0086028 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.4 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.0 GO:0021650 vestibulocochlear nerve morphogenesis(GO:0021648) vestibulocochlear nerve formation(GO:0021650)
0.0 0.1 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.0 0.2 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.1 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.0 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.4 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.1 0.2 GO:0031523 Myb complex(GO:0031523)
0.0 0.1 GO:0044753 amphisome(GO:0044753)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.1 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 0.3 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0097413 Lewy body(GO:0097413)
0.0 0.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.0 GO:0035101 FACT complex(GO:0035101)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.0 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.0 0.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.2 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.0 GO:0032127 dense core granule membrane(GO:0032127) microvesicle(GO:1990742)
0.0 0.5 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0031105 septin complex(GO:0031105)
0.0 0.8 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0004974 leukotriene B4 receptor activity(GO:0001632) leukotriene receptor activity(GO:0004974)
0.1 0.5 GO:0045569 TRAIL binding(GO:0045569)
0.1 0.3 GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
0.1 0.2 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.1 0.2 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 0.3 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.2 GO:1904854 proteasome core complex binding(GO:1904854)
0.1 0.2 GO:0008480 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.0 0.6 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.5 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.1 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.0 0.2 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.1 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.0 0.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0004673 protein histidine kinase activity(GO:0004673)
0.0 0.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.8 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.0 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.6 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex