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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ZFHX3

Z-value: 0.47

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Transcription factors associated with ZFHX3

Gene Symbol Gene ID Gene Info
ZFHX3
ENSG00000140836.10 zinc finger homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZFHX3hg19_v2_chr16_-_73082274_730822740.453.7e-01Click!

Activity profile of ZFHX3 motif

Sorted Z-values of ZFHX3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_61151306 0.35 ENST00000580068.1
ENST00000580466.1
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr5_+_140625147 0.25 ENST00000231173.3
PCDHB15
protocadherin beta 15
chr12_-_91546926 0.23 ENST00000550758.1
DCN
decorin
chr11_-_58378759 0.22 ENST00000601906.1
AP001350.1
Uncharacterized protein
chr2_-_87248975 0.18 ENST00000409310.2
ENST00000355705.3
PLGLB1
plasminogen-like B1
chr15_+_76352178 0.16 ENST00000388942.3
C15orf27
chromosome 15 open reading frame 27
chr12_-_2944184 0.16 ENST00000337508.4
NRIP2
nuclear receptor interacting protein 2
chr12_+_65996599 0.12 ENST00000539116.1
ENST00000541391.1
RP11-221N13.3
RP11-221N13.3
chr11_+_57559005 0.12 ENST00000534647.1
CTNND1
catenin (cadherin-associated protein), delta 1
chr14_+_39703112 0.11 ENST00000555143.1
ENST00000280082.3
MIA2
melanoma inhibitory activity 2
chr10_-_75226166 0.11 ENST00000544628.1
PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr20_+_42187608 0.10 ENST00000373100.1
SGK2
serum/glucocorticoid regulated kinase 2
chr16_-_14109841 0.10 ENST00000576797.1
ENST00000575424.1
CTD-2135D7.5
CTD-2135D7.5
chr22_-_30970498 0.10 ENST00000431313.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chrM_-_14670 0.10 ENST00000361681.2
MT-ND6
mitochondrially encoded NADH dehydrogenase 6
chrM_+_9207 0.10 ENST00000362079.2
MT-CO3
mitochondrially encoded cytochrome c oxidase III
chr11_-_61687739 0.09 ENST00000531922.1
ENST00000301773.5
RAB3IL1
RAB3A interacting protein (rabin3)-like 1
chr17_+_4692230 0.09 ENST00000331264.7
GLTPD2
glycolipid transfer protein domain containing 2
chr22_-_30722912 0.09 ENST00000215790.7
TBC1D10A
TBC1 domain family, member 10A
chr4_+_3443614 0.09 ENST00000382774.3
ENST00000511533.1
HGFAC
HGF activator
chr16_-_69385681 0.09 ENST00000288025.3
TMED6
transmembrane emp24 protein transport domain containing 6
chr14_+_95027772 0.09 ENST00000555095.1
ENST00000298841.5
ENST00000554220.1
ENST00000553780.1
SERPINA4
SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr11_-_559377 0.08 ENST00000486629.1
C11orf35
chromosome 11 open reading frame 35
chr4_-_69111401 0.08 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr16_-_75284758 0.08 ENST00000561970.1
BCAR1
breast cancer anti-estrogen resistance 1
chrM_+_10053 0.08 ENST00000361227.2
MT-ND3
mitochondrially encoded NADH dehydrogenase 3
chrM_+_10464 0.07 ENST00000361335.1
MT-ND4L
mitochondrially encoded NADH dehydrogenase 4L
chr3_-_114477787 0.07 ENST00000464560.1
ZBTB20
zinc finger and BTB domain containing 20
chr1_-_168464875 0.07 ENST00000422253.1
RP5-968D22.3
RP5-968D22.3
chr6_-_116447283 0.06 ENST00000452729.1
ENST00000243222.4
COL10A1
collagen, type X, alpha 1
chrM_+_8527 0.06 ENST00000361899.2
MT-ATP6
mitochondrially encoded ATP synthase 6
chr12_-_11184006 0.06 ENST00000390675.2
TAS2R31
taste receptor, type 2, member 31
chrX_-_110655306 0.06 ENST00000371993.2
DCX
doublecortin
chr12_+_59989918 0.06 ENST00000547379.1
ENST00000549465.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr17_-_60142609 0.06 ENST00000397786.2
MED13
mediator complex subunit 13
chr6_+_161123270 0.05 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
PLG
plasminogen
chr14_-_104408645 0.05 ENST00000557640.1
RD3L
retinal degeneration 3-like
chr7_+_100026406 0.05 ENST00000414441.1
MEPCE
methylphosphate capping enzyme
chr6_+_126070726 0.05 ENST00000368364.3
HEY2
hes-related family bHLH transcription factor with YRPW motif 2
chr19_+_926000 0.05 ENST00000263620.3
ARID3A
AT rich interactive domain 3A (BRIGHT-like)
chr11_+_6220376 0.05 ENST00000311352.2
OR52W1
olfactory receptor, family 52, subfamily W, member 1
chr2_+_190541153 0.05 ENST00000313581.4
ENST00000438402.2
ENST00000431575.2
ENST00000281412.6
ANKAR
ankyrin and armadillo repeat containing
chr16_+_87636474 0.05 ENST00000284262.2
JPH3
junctophilin 3
chr12_+_54410664 0.05 ENST00000303406.4
HOXC4
homeobox C4
chr1_-_153585539 0.04 ENST00000368706.4
S100A16
S100 calcium binding protein A16
chrY_-_20935572 0.04 ENST00000382852.1
ENST00000344884.4
ENST00000304790.3
HSFY2
heat shock transcription factor, Y linked 2
chr9_-_95298314 0.04 ENST00000344604.5
ENST00000375540.1
ECM2
extracellular matrix protein 2, female organ and adipocyte specific
chr5_+_60933634 0.04 ENST00000505642.1
C5orf64
chromosome 5 open reading frame 64
chr7_-_7575477 0.04 ENST00000399429.3
COL28A1
collagen, type XXVIII, alpha 1
chr19_+_54466179 0.04 ENST00000270458.2
CACNG8
calcium channel, voltage-dependent, gamma subunit 8
chr12_+_53835383 0.04 ENST00000429243.2
PRR13
proline rich 13
chr5_-_115890554 0.04 ENST00000509665.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr12_+_53835425 0.04 ENST00000549924.1
PRR13
proline rich 13
chr1_-_160549235 0.04 ENST00000368054.3
ENST00000368048.3
ENST00000311224.4
ENST00000368051.3
ENST00000534968.1
CD84
CD84 molecule
chr22_-_30970560 0.03 ENST00000402369.1
ENST00000406361.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chrY_+_20708557 0.03 ENST00000307393.2
ENST00000309834.4
ENST00000382856.2
HSFY1
heat shock transcription factor, Y-linked 1
chr6_+_25754927 0.03 ENST00000377905.4
ENST00000439485.2
SLC17A4
solute carrier family 17, member 4
chr8_-_145754428 0.03 ENST00000527462.1
ENST00000313465.5
ENST00000524821.1
C8orf82
chromosome 8 open reading frame 82
chr19_-_46234119 0.03 ENST00000317683.3
FBXO46
F-box protein 46
chr7_+_150725510 0.03 ENST00000461373.1
ENST00000358849.4
ENST00000297504.6
ENST00000542328.1
ENST00000498578.1
ENST00000356058.4
ENST00000477719.1
ENST00000477092.1
ABCB8
ATP-binding cassette, sub-family B (MDR/TAP), member 8
chr6_-_31681839 0.03 ENST00000409239.1
ENST00000461287.1
LY6G6E
XXbac-BPG32J3.20
lymphocyte antigen 6 complex, locus G6E (pseudogene)
Uncharacterized protein
chr18_+_20494078 0.03 ENST00000579124.1
ENST00000577588.1
ENST00000582354.1
ENST00000581819.1
RBBP8
retinoblastoma binding protein 8
chr8_-_101733794 0.03 ENST00000523555.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr22_+_39101728 0.03 ENST00000216044.5
ENST00000484657.1
GTPBP1
GTP binding protein 1
chr1_+_76540386 0.03 ENST00000328299.3
ST6GALNAC3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr22_-_22337204 0.03 ENST00000430142.1
ENST00000357179.5
TOP3B
topoisomerase (DNA) III beta
chr1_-_197036364 0.02 ENST00000367412.1
F13B
coagulation factor XIII, B polypeptide
chr20_+_42187682 0.02 ENST00000373092.3
ENST00000373077.1
SGK2
serum/glucocorticoid regulated kinase 2
chr2_+_88047606 0.02 ENST00000359481.4
PLGLB2
plasminogen-like B2
chr2_+_105050794 0.02 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
AC013402.2
long intergenic non-protein coding RNA 1102
chr1_-_227505289 0.02 ENST00000366765.3
CDC42BPA
CDC42 binding protein kinase alpha (DMPK-like)
chr12_+_59989791 0.02 ENST00000552432.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chrX_+_1710484 0.02 ENST00000313871.3
ENST00000381261.3
AKAP17A
A kinase (PRKA) anchor protein 17A
chr12_+_53835539 0.02 ENST00000547368.1
ENST00000379786.4
ENST00000551945.1
PRR13
proline rich 13
chr15_+_58724184 0.02 ENST00000433326.2
LIPC
lipase, hepatic
chr3_+_46919235 0.02 ENST00000449590.1
PTH1R
parathyroid hormone 1 receptor
chr17_+_17685422 0.02 ENST00000395774.1
RAI1
retinoic acid induced 1
chr3_-_108248169 0.02 ENST00000273353.3
MYH15
myosin, heavy chain 15
chr8_-_87242589 0.01 ENST00000419776.2
ENST00000297524.3
SLC7A13
solute carrier family 7 (anionic amino acid transporter), member 13
chr6_+_34204642 0.01 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1
high mobility group AT-hook 1
chr6_-_152793728 0.01 ENST00000495090.2
SYNE1
spectrin repeat containing, nuclear envelope 1
chr8_+_98900132 0.01 ENST00000520016.1
MATN2
matrilin 2
chr2_-_60780607 0.01 ENST00000537768.1
ENST00000335712.6
ENST00000356842.4
BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chr5_+_118690466 0.01 ENST00000503646.1
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr12_+_53835508 0.01 ENST00000551003.1
ENST00000549068.1
ENST00000549740.1
ENST00000546581.1
ENST00000549581.1
ENST00000541275.1
PRR13
PCBP2
proline rich 13
poly(rC) binding protein 2
chrX_-_15288154 0.01 ENST00000380483.3
ENST00000380485.3
ENST00000380488.4
ASB9
ankyrin repeat and SOCS box containing 9
chr7_-_44580861 0.01 ENST00000546276.1
ENST00000289547.4
ENST00000381160.3
ENST00000423141.1
NPC1L1
NPC1-like 1
chr2_-_60780536 0.01 ENST00000538214.1
BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chr11_-_107729887 0.01 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr11_-_107729287 0.01 ENST00000375682.4
SLC35F2
solute carrier family 35, member F2
chr3_+_35722424 0.01 ENST00000396481.2
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr8_-_70745575 0.01 ENST00000524945.1
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr2_-_60780546 0.01 ENST00000358510.4
BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chr7_+_48211048 0.01 ENST00000435803.1
ABCA13
ATP-binding cassette, sub-family A (ABC1), member 13
chr9_-_95298254 0.01 ENST00000444490.2
ECM2
extracellular matrix protein 2, female organ and adipocyte specific
chrX_+_9431324 0.01 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr19_+_50016610 0.01 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr22_+_31488433 0.00 ENST00000455608.1
SMTN
smoothelin
chr2_-_14541060 0.00 ENST00000418420.1
ENST00000417751.1
LINC00276
long intergenic non-protein coding RNA 276
chr11_-_125366018 0.00 ENST00000527534.1
FEZ1
fasciculation and elongation protein zeta 1 (zygin I)
chr3_+_35722487 0.00 ENST00000441454.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr19_-_58864848 0.00 ENST00000263100.3
A1BG
alpha-1-B glycoprotein
chr1_-_247921982 0.00 ENST00000408896.2
OR1C1
olfactory receptor, family 1, subfamily C, member 1
chr17_-_26697304 0.00 ENST00000536498.1
VTN
vitronectin

Network of associatons between targets according to the STRING database.

First level regulatory network of ZFHX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.1 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.0 0.1 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0036027 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.0 0.1 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.1 GO:1904854 proteasome core complex binding(GO:1904854)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.0 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)