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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ZIC3_ZIC4

Z-value: 0.38

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Transcription factors associated with ZIC3_ZIC4

Gene Symbol Gene ID Gene Info
ZIC3
ENSG00000156925.7 Zic family member 3
ZIC4
ENSG00000174963.13 Zic family member 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZIC3hg19_v2_chrX_+_136648297_1366483190.384.6e-01Click!

Activity profile of ZIC3_ZIC4 motif

Sorted Z-values of ZIC3_ZIC4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_302918 0.25 ENST00000599994.1
AC187652.1
Protein LOC100996433
chr9_-_34662651 0.22 ENST00000259631.4
CCL27
chemokine (C-C motif) ligand 27
chr11_+_73675873 0.18 ENST00000537753.1
ENST00000542350.1
DNAJB13
DnaJ (Hsp40) homolog, subfamily B, member 13
chr17_+_39405939 0.18 ENST00000334109.2
KRTAP9-4
keratin associated protein 9-4
chr1_+_154378049 0.17 ENST00000512471.1
IL6R
interleukin 6 receptor
chr2_-_67442409 0.15 ENST00000414404.1
ENST00000433133.1
AC078941.1
AC078941.1
chr10_-_9801179 0.15 ENST00000419836.1
RP5-1051H14.2
RP5-1051H14.2
chr19_+_10531150 0.14 ENST00000352831.6
PDE4A
phosphodiesterase 4A, cAMP-specific
chr9_+_139738867 0.13 ENST00000436881.1
C9orf172
chromosome 9 open reading frame 172
chr3_-_118753792 0.13 ENST00000480431.1
IGSF11
immunoglobulin superfamily, member 11
chr16_+_4364762 0.12 ENST00000262366.3
GLIS2
GLIS family zinc finger 2
chr17_-_73840614 0.12 ENST00000586108.1
UNC13D
unc-13 homolog D (C. elegans)
chr22_-_41842781 0.12 ENST00000434408.1
TOB2
transducer of ERBB2, 2
chr19_-_40790993 0.12 ENST00000596634.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr11_+_73676281 0.11 ENST00000543947.1
DNAJB13
DnaJ (Hsp40) homolog, subfamily B, member 13
chr8_+_1711918 0.11 ENST00000331222.4
CLN8
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr19_-_12992244 0.11 ENST00000538460.1
DNASE2
deoxyribonuclease II, lysosomal
chr3_-_87039662 0.11 ENST00000494229.1
VGLL3
vestigial like 3 (Drosophila)
chr11_-_64014379 0.11 ENST00000309318.3
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr16_+_2570340 0.11 ENST00000568263.1
ENST00000293971.6
ENST00000302956.4
ENST00000413459.3
ENST00000566706.1
ENST00000569879.1
AMDHD2
amidohydrolase domain containing 2
chr16_+_2059872 0.11 ENST00000567649.1
NPW
neuropeptide W
chr1_-_16400086 0.11 ENST00000375662.4
FAM131C
family with sequence similarity 131, member C
chr20_-_31172598 0.11 ENST00000201961.2
C20orf112
chromosome 20 open reading frame 112
chr3_+_195413160 0.10 ENST00000599448.1
LINC00969
long intergenic non-protein coding RNA 969
chr5_+_72509751 0.10 ENST00000515556.1
ENST00000513379.1
ENST00000427584.2
RP11-60A8.1
RP11-60A8.1
chr19_-_40790729 0.10 ENST00000423127.1
ENST00000583859.1
ENST00000456441.1
ENST00000452077.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr16_+_28996572 0.09 ENST00000360872.5
ENST00000566177.1
ENST00000354453.4
LAT
linker for activation of T cells
chr17_-_73840415 0.09 ENST00000592386.1
ENST00000412096.2
ENST00000586147.1
UNC13D
unc-13 homolog D (C. elegans)
chr22_+_29702572 0.09 ENST00000407647.2
ENST00000416823.1
ENST00000428622.1
GAS2L1
growth arrest-specific 2 like 1
chr11_+_58938903 0.09 ENST00000532982.1
DTX4
deltex homolog 4 (Drosophila)
chr9_-_130742792 0.09 ENST00000373095.1
FAM102A
family with sequence similarity 102, member A
chr11_-_67272794 0.09 ENST00000436757.2
ENST00000356404.3
PITPNM1
phosphatidylinositol transfer protein, membrane-associated 1
chr17_-_78194124 0.09 ENST00000570427.1
ENST00000570923.1
SGSH
N-sulfoglucosamine sulfohydrolase
chr8_-_145980808 0.08 ENST00000525191.1
ZNF251
zinc finger protein 251
chr1_+_3370990 0.08 ENST00000378378.4
ARHGEF16
Rho guanine nucleotide exchange factor (GEF) 16
chr19_-_40791302 0.08 ENST00000392038.2
ENST00000578123.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr6_-_85473073 0.08 ENST00000606621.1
TBX18
T-box 18
chr7_-_135412925 0.08 ENST00000354042.4
SLC13A4
solute carrier family 13 (sodium/sulfate symporter), member 4
chr17_-_4890919 0.08 ENST00000572543.1
ENST00000381311.5
ENST00000348066.3
ENST00000358183.4
CAMTA2
calmodulin binding transcription activator 2
chr17_-_73840774 0.08 ENST00000207549.4
UNC13D
unc-13 homolog D (C. elegans)
chrX_+_71996972 0.08 ENST00000334036.5
DMRTC1B
DMRT-like family C1B
chr11_-_62477313 0.08 ENST00000464544.1
ENST00000530009.1
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr16_+_29466426 0.07 ENST00000567248.1
SLX1B
SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
chr17_-_78194147 0.07 ENST00000534910.1
ENST00000326317.6
SGSH
N-sulfoglucosamine sulfohydrolase
chr7_-_44924939 0.07 ENST00000395699.2
PURB
purine-rich element binding protein B
chr11_+_637246 0.07 ENST00000176183.5
DRD4
dopamine receptor D4
chr22_-_19466643 0.07 ENST00000474226.1
UFD1L
ubiquitin fusion degradation 1 like (yeast)
chr1_+_38273988 0.07 ENST00000446260.2
C1orf122
chromosome 1 open reading frame 122
chr16_+_777739 0.07 ENST00000563792.1
HAGHL
hydroxyacylglutathione hydrolase-like
chr16_-_2059797 0.07 ENST00000563630.1
ZNF598
zinc finger protein 598
chr2_-_107502456 0.07 ENST00000419159.2
ST6GAL2
ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
chr9_-_114245938 0.07 ENST00000602447.1
KIAA0368
KIAA0368
chr1_-_146644036 0.07 ENST00000425272.2
PRKAB2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr7_+_150758304 0.07 ENST00000482950.1
ENST00000463414.1
ENST00000310317.5
SLC4A2
solute carrier family 4 (anion exchanger), member 2
chr19_-_40791211 0.07 ENST00000579047.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr19_-_12992274 0.07 ENST00000592506.1
ENST00000222219.3
DNASE2
deoxyribonuclease II, lysosomal
chr12_+_49932886 0.07 ENST00000257981.6
KCNH3
potassium voltage-gated channel, subfamily H (eag-related), member 3
chr9_-_114246332 0.07 ENST00000602978.1
KIAA0368
KIAA0368
chr19_-_40724246 0.07 ENST00000311308.6
TTC9B
tetratricopeptide repeat domain 9B
chr19_-_40791160 0.07 ENST00000358335.5
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr1_+_38273818 0.07 ENST00000373042.4
C1orf122
chromosome 1 open reading frame 122
chr4_+_52917451 0.07 ENST00000295213.4
ENST00000419395.2
SPATA18
spermatogenesis associated 18
chr22_-_22221900 0.07 ENST00000215832.6
ENST00000398822.3
MAPK1
mitogen-activated protein kinase 1
chr9_+_134269439 0.07 ENST00000405995.1
PRRC2B
proline-rich coiled-coil 2B
chr15_+_73976715 0.07 ENST00000558689.1
ENST00000560786.2
ENST00000561213.1
ENST00000563584.1
ENST00000561416.1
CD276
CD276 molecule
chr20_+_816695 0.07 ENST00000246100.3
FAM110A
family with sequence similarity 110, member A
chr9_+_131580734 0.07 ENST00000372642.4
ENDOG
endonuclease G
chr19_-_37096139 0.06 ENST00000585983.1
ENST00000585960.1
ENST00000586115.1
ZNF529
zinc finger protein 529
chr16_+_58498177 0.06 ENST00000567454.1
NDRG4
NDRG family member 4
chr7_+_65540853 0.06 ENST00000380839.4
ENST00000395332.3
ENST00000362000.5
ENST00000395331.3
ASL
argininosuccinate lyase
chr10_+_71561630 0.06 ENST00000398974.3
ENST00000398971.3
ENST00000398968.3
ENST00000398966.3
ENST00000398964.3
ENST00000398969.3
ENST00000356340.3
ENST00000398972.3
ENST00000398973.3
COL13A1
collagen, type XIII, alpha 1
chr17_-_43045439 0.06 ENST00000253407.3
C1QL1
complement component 1, q subcomponent-like 1
chr15_+_31619013 0.06 ENST00000307145.3
KLF13
Kruppel-like factor 13
chr19_+_49617581 0.06 ENST00000391864.3
LIN7B
lin-7 homolog B (C. elegans)
chr7_-_74867509 0.06 ENST00000426327.3
GATSL2
GATS protein-like 2
chr5_+_139055055 0.06 ENST00000511457.1
CXXC5
CXXC finger protein 5
chr19_+_13906250 0.06 ENST00000254323.2
ZSWIM4
zinc finger, SWIM-type containing 4
chr17_-_78194716 0.06 ENST00000576707.1
SGSH
N-sulfoglucosamine sulfohydrolase
chr17_+_5981270 0.06 ENST00000571973.1
WSCD1
WSC domain containing 1
chr10_-_134145321 0.06 ENST00000368625.4
ENST00000368619.3
ENST00000456004.1
ENST00000368620.2
STK32C
serine/threonine kinase 32C
chr17_+_45331184 0.06 ENST00000559488.1
ENST00000571680.1
ENST00000435993.2
ITGB3
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
chr17_-_40829026 0.06 ENST00000412503.1
PLEKHH3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr7_+_99775520 0.06 ENST00000317296.5
ENST00000422690.1
ENST00000439782.1
STAG3
stromal antigen 3
chr15_-_91565770 0.06 ENST00000535906.1
ENST00000333371.3
VPS33B
vacuolar protein sorting 33 homolog B (yeast)
chr19_-_49314269 0.05 ENST00000545387.2
ENST00000316273.6
ENST00000402551.1
ENST00000598162.1
ENST00000599246.1
BCAT2
branched chain amino-acid transaminase 2, mitochondrial
chr5_+_145316120 0.05 ENST00000359120.4
SH3RF2
SH3 domain containing ring finger 2
chr1_-_45308616 0.05 ENST00000447098.2
ENST00000372192.3
PTCH2
patched 2
chr11_+_76092353 0.05 ENST00000530460.1
ENST00000321844.4
RP11-111M22.2
Homo sapiens putative uncharacterized protein FLJ37770-like (LOC100506127), mRNA.
chr5_+_140718396 0.05 ENST00000394576.2
PCDHGA2
protocadherin gamma subfamily A, 2
chr1_+_43148059 0.05 ENST00000321358.7
ENST00000332220.6
YBX1
Y box binding protein 1
chr22_-_41636929 0.05 ENST00000216241.9
CHADL
chondroadherin-like
chr15_-_91565743 0.05 ENST00000535843.1
VPS33B
vacuolar protein sorting 33 homolog B (yeast)
chr11_-_1036706 0.05 ENST00000421673.2
MUC6
mucin 6, oligomeric mucus/gel-forming
chr17_-_7531121 0.05 ENST00000573566.1
ENST00000269298.5
SAT2
spermidine/spermine N1-acetyltransferase family member 2
chr20_-_56286479 0.05 ENST00000265626.4
PMEPA1
prostate transmembrane protein, androgen induced 1
chr16_+_4897912 0.05 ENST00000545171.1
UBN1
ubinuclein 1
chr1_-_31381528 0.05 ENST00000339394.6
SDC3
syndecan 3
chr5_+_139055021 0.05 ENST00000502716.1
ENST00000503511.1
CXXC5
CXXC finger protein 5
chr9_-_140082983 0.05 ENST00000323927.2
ANAPC2
anaphase promoting complex subunit 2
chr19_-_39390212 0.05 ENST00000437828.1
SIRT2
sirtuin 2
chr19_+_54926621 0.05 ENST00000376530.3
ENST00000445095.1
ENST00000391739.3
ENST00000376531.3
TTYH1
tweety family member 1
chr12_-_125052010 0.05 ENST00000458234.1
NCOR2
nuclear receptor corepressor 2
chr18_+_2846972 0.05 ENST00000254528.3
EMILIN2
elastin microfibril interfacer 2
chr9_+_115913222 0.05 ENST00000259392.3
SLC31A2
solute carrier family 31 (copper transporter), member 2
chr16_+_30205225 0.05 ENST00000345535.4
ENST00000251303.6
SLX1A
SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)
chr15_+_75074410 0.05 ENST00000439220.2
CSK
c-src tyrosine kinase
chr15_+_75074385 0.05 ENST00000220003.9
CSK
c-src tyrosine kinase
chr1_-_151119087 0.05 ENST00000341697.3
ENST00000368914.3
SEMA6C
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
chr10_-_131762105 0.05 ENST00000368648.3
ENST00000355311.5
EBF3
early B-cell factor 3
chr12_+_121163538 0.05 ENST00000242592.4
ACADS
acyl-CoA dehydrogenase, C-2 to C-3 short chain
chr9_+_116638630 0.05 ENST00000452710.1
ENST00000374124.4
ZNF618
zinc finger protein 618
chr11_-_65667997 0.05 ENST00000312562.2
ENST00000534222.1
FOSL1
FOS-like antigen 1
chr12_-_59314246 0.05 ENST00000320743.3
LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr6_+_15249128 0.05 ENST00000397311.3
JARID2
jumonji, AT rich interactive domain 2
chr20_+_60698180 0.05 ENST00000361670.3
LSM14B
LSM14B, SCD6 homolog B (S. cerevisiae)
chr1_-_21503337 0.05 ENST00000400422.1
ENST00000602326.1
ENST00000411888.1
ENST00000438975.1
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr6_-_38607673 0.05 ENST00000481247.1
BTBD9
BTB (POZ) domain containing 9
chr17_-_1083078 0.05 ENST00000574266.1
ENST00000302538.5
ABR
active BCR-related
chr17_-_56065540 0.05 ENST00000583932.1
VEZF1
vascular endothelial zinc finger 1
chr16_+_29465822 0.04 ENST00000330181.5
ENST00000351581.4
SLX1B
SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
chr20_+_35201857 0.04 ENST00000373874.2
TGIF2
TGFB-induced factor homeobox 2
chr2_-_99552620 0.04 ENST00000428096.1
ENST00000397899.2
ENST00000420294.1
KIAA1211L
KIAA1211-like
chr9_+_140083099 0.04 ENST00000322310.5
SSNA1
Sjogren syndrome nuclear autoantigen 1
chr1_+_6052700 0.04 ENST00000378092.1
ENST00000445501.1
KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr7_+_149571045 0.04 ENST00000479613.1
ENST00000606024.1
ENST00000464662.1
ENST00000425642.2
ATP6V0E2
ATPase, H+ transporting V0 subunit e2
chr17_+_47572647 0.04 ENST00000172229.3
NGFR
nerve growth factor receptor
chr11_-_116968987 0.04 ENST00000434315.2
ENST00000292055.4
ENST00000375288.1
ENST00000542607.1
ENST00000445177.1
ENST00000375300.1
ENST00000446921.2
SIK3
SIK family kinase 3
chr20_+_35201993 0.04 ENST00000373872.4
TGIF2
TGFB-induced factor homeobox 2
chrX_-_30326445 0.04 ENST00000378963.1
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr19_-_12833361 0.04 ENST00000592287.1
TNPO2
transportin 2
chr19_+_984313 0.04 ENST00000251289.5
ENST00000587001.2
ENST00000607440.1
WDR18
WD repeat domain 18
chr17_+_59477233 0.04 ENST00000240328.3
TBX2
T-box 2
chr7_-_4923259 0.04 ENST00000536091.1
RADIL
Ras association and DIL domains
chr2_-_109605663 0.04 ENST00000409271.1
ENST00000258443.2
ENST00000376651.1
EDAR
ectodysplasin A receptor
chr1_-_159915386 0.04 ENST00000361509.3
ENST00000368094.1
IGSF9
immunoglobulin superfamily, member 9
chr16_-_69364467 0.04 ENST00000288022.1
PDF
peptide deformylase (mitochondrial)
chr14_+_105886150 0.04 ENST00000331320.7
ENST00000406191.1
MTA1
metastasis associated 1
chr16_+_28996364 0.04 ENST00000564277.1
LAT
linker for activation of T cells
chr7_+_65540780 0.04 ENST00000304874.9
ASL
argininosuccinate lyase
chr19_+_59055814 0.04 ENST00000594806.1
ENST00000253024.5
ENST00000341753.6
TRIM28
tripartite motif containing 28
chr5_+_176731572 0.04 ENST00000503853.1
PRELID1
PRELI domain containing 1
chr2_-_98612379 0.04 ENST00000425805.2
TMEM131
transmembrane protein 131
chr3_-_112356944 0.04 ENST00000461431.1
CCDC80
coiled-coil domain containing 80
chr11_+_66790816 0.04 ENST00000527043.1
SYT12
synaptotagmin XII
chr8_-_135708787 0.04 ENST00000520356.1
ENST00000520727.1
ENST00000520214.1
ENST00000518191.1
ENST00000429442.2
ZFAT
zinc finger and AT hook domain containing
chr10_+_134145614 0.04 ENST00000368615.3
ENST00000392638.2
ENST00000344079.5
ENST00000356571.4
ENST00000368614.3
LRRC27
leucine rich repeat containing 27
chr16_-_88717482 0.04 ENST00000261623.3
CYBA
cytochrome b-245, alpha polypeptide
chr5_+_137688285 0.04 ENST00000314358.5
KDM3B
lysine (K)-specific demethylase 3B
chr20_+_44563267 0.04 ENST00000372409.3
PCIF1
PDX1 C-terminal inhibiting factor 1
chr17_-_21454898 0.04 ENST00000391411.5
ENST00000412778.3
C17orf51
chromosome 17 open reading frame 51
chr18_+_13217965 0.04 ENST00000587905.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr19_-_18385221 0.04 ENST00000595654.2
ENST00000593659.1
ENST00000599528.1
KIAA1683
KIAA1683
chr14_-_100841794 0.04 ENST00000556295.1
ENST00000554820.1
WARS
tryptophanyl-tRNA synthetase
chr9_+_116638562 0.04 ENST00000374126.5
ENST00000288466.7
ZNF618
zinc finger protein 618
chr17_-_4871085 0.04 ENST00000575142.1
ENST00000206020.3
SPAG7
sperm associated antigen 7
chr17_-_79623597 0.04 ENST00000574024.1
ENST00000331056.5
PDE6G
phosphodiesterase 6G, cGMP-specific, rod, gamma
chr2_-_98280383 0.04 ENST00000289228.5
ACTR1B
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr16_+_67840986 0.04 ENST00000561639.1
ENST00000567852.1
ENST00000565148.1
ENST00000388833.3
ENST00000561654.1
ENST00000431934.2
TSNAXIP1
translin-associated factor X interacting protein 1
chr1_+_85527987 0.04 ENST00000326813.8
ENST00000294664.6
ENST00000528899.1
WDR63
WD repeat domain 63
chr2_-_73869508 0.04 ENST00000272425.3
NAT8
N-acetyltransferase 8 (GCN5-related, putative)
chr2_+_11273179 0.04 ENST00000381585.3
ENST00000405022.3
C2orf50
chromosome 2 open reading frame 50
chr19_+_34287751 0.04 ENST00000590771.1
ENST00000589786.1
ENST00000284006.6
ENST00000588881.1
KCTD15
potassium channel tetramerization domain containing 15
chr7_-_752577 0.04 ENST00000544935.1
ENST00000430040.1
ENST00000456696.2
ENST00000406797.1
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr4_-_860950 0.04 ENST00000511980.1
ENST00000510799.1
GAK
cyclin G associated kinase
chr16_+_89753070 0.04 ENST00000353379.7
ENST00000505473.1
ENST00000564192.1
CDK10
cyclin-dependent kinase 10
chr5_-_126366500 0.04 ENST00000308660.5
MARCH3
membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase
chr7_-_752074 0.04 ENST00000360274.4
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr12_-_51785393 0.04 ENST00000605138.1
ENST00000604381.1
ENST00000605055.1
ENST00000605617.1
GALNT6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)
chr11_-_65667884 0.04 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOSL1
FOS-like antigen 1
chr19_-_49314169 0.04 ENST00000597011.1
ENST00000601681.1
BCAT2
branched chain amino-acid transaminase 2, mitochondrial
chr16_-_31085514 0.04 ENST00000300849.4
ZNF668
zinc finger protein 668
chr22_-_19165917 0.04 ENST00000451283.1
SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr17_+_75276643 0.04 ENST00000589070.1
SEPT9
septin 9
chr4_+_492985 0.04 ENST00000296306.7
ENST00000536264.1
ENST00000310340.5
ENST00000453061.2
ENST00000504346.1
ENST00000503111.1
ENST00000383028.4
ENST00000509768.1
PIGG
phosphatidylinositol glycan anchor biosynthesis, class G
chr6_+_33168637 0.04 ENST00000374677.3
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr18_+_11752040 0.04 ENST00000423027.3
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr14_-_100841930 0.04 ENST00000555031.1
ENST00000553395.1
ENST00000553545.1
ENST00000344102.5
ENST00000556338.1
ENST00000392882.2
ENST00000553934.1
WARS
tryptophanyl-tRNA synthetase
chr16_+_67465016 0.04 ENST00000326152.5
HSD11B2
hydroxysteroid (11-beta) dehydrogenase 2
chr11_-_57004658 0.04 ENST00000606794.1
APLNR
apelin receptor
chr15_-_70388599 0.04 ENST00000560996.1
ENST00000558201.1
TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr11_+_120081475 0.04 ENST00000328965.4
OAF
OAF homolog (Drosophila)
chr17_+_27055798 0.04 ENST00000268766.6
NEK8
NIMA-related kinase 8
chr20_+_3870024 0.04 ENST00000610179.1
PANK2
pantothenate kinase 2
chr18_+_46065483 0.04 ENST00000382998.4
CTIF
CBP80/20-dependent translation initiation factor
chr19_+_33685490 0.03 ENST00000253193.7
LRP3
low density lipoprotein receptor-related protein 3
chr16_-_30204987 0.03 ENST00000569282.1
ENST00000567436.1
BOLA2B
bolA family member 2B
chr20_-_30458432 0.03 ENST00000375966.4
ENST00000278979.3
DUSP15
dual specificity phosphatase 15
chr16_+_28834531 0.03 ENST00000570200.1
ATXN2L
ataxin 2-like
chr9_-_139371533 0.03 ENST00000290037.6
ENST00000431893.2
ENST00000371706.3
SEC16A
SEC16 homolog A (S. cerevisiae)
chr7_-_99774945 0.03 ENST00000292377.2
GPC2
glypican 2
chr17_-_40828969 0.03 ENST00000591022.1
ENST00000587627.1
ENST00000293349.6
PLEKHH3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr11_+_47291193 0.03 ENST00000428807.1
ENST00000402799.1
ENST00000406482.1
ENST00000349238.3
ENST00000311027.5
ENST00000407859.3
ENST00000395344.3
ENST00000444117.1
MADD
MAP-kinase activating death domain
chr16_-_18470696 0.03 ENST00000427999.2
RP11-1212A22.4
LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1
chr17_+_38219063 0.03 ENST00000584985.1
ENST00000264637.4
ENST00000450525.2
THRA
thyroid hormone receptor, alpha
chr6_+_33168597 0.03 ENST00000374675.3
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr7_-_5569588 0.03 ENST00000417101.1
ACTB
actin, beta
chr11_-_32457075 0.03 ENST00000448076.3
WT1
Wilms tumor 1
chr1_+_201617450 0.03 ENST00000295624.6
ENST00000367297.4
ENST00000367300.3
NAV1
neuron navigator 1
chr22_-_47134077 0.03 ENST00000541677.1
ENST00000216264.8
CERK
ceramide kinase
chr19_+_48949030 0.03 ENST00000253237.5
GRWD1
glutamate-rich WD repeat containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ZIC3_ZIC4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0002432 granuloma formation(GO:0002432)
0.1 0.4 GO:0071486 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 0.3 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.2 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.1 GO:0060829 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.0 0.2 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.0 GO:0060823 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.1 GO:0019858 cytosine metabolic process(GO:0019858)
0.0 0.1 GO:0006550 isoleucine catabolic process(GO:0006550)
0.0 0.1 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.0 0.1 GO:0099558 maintenance of synapse structure(GO:0099558)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.1 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.1 GO:0060994 regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994)
0.0 0.1 GO:0070446 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.0 0.1 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0 0.1 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.0 GO:1901207 regulation of heart looping(GO:1901207)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.1 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.1 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.0 0.1 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.1 GO:0051586 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.0 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.0 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 0.1 GO:0044301 climbing fiber(GO:0044301)
0.0 0.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.0 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.0 GO:0097598 sperm cytoplasmic droplet(GO:0097598)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0016250 N-sulfoglucosamine sulfohydrolase activity(GO:0016250) hydrolase activity, acting on acid sulfur-nitrogen bonds(GO:0016826)
0.1 0.2 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.1 0.2 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.0 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.1 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.0 0.1 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.2 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0 0.1 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.0 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.0 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.0 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.0 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation