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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ZNF350

Z-value: 0.78

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Transcription factors associated with ZNF350

Gene Symbol Gene ID Gene Info
ENSG00000256683.2 zinc finger protein 350

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF350hg19_v2_chr19_-_52489923_524901130.128.1e-01Click!

Activity profile of ZNF350 motif

Sorted Z-values of ZNF350 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr21_-_30365136 0.54 ENST00000361371.5
ENST00000389194.2
ENST00000389195.2
listerin E3 ubiquitin protein ligase 1
chr19_+_57050317 0.52 ENST00000301318.3
ENST00000591844.1
ZFP28 zinc finger protein
chr4_-_99578776 0.49 ENST00000515287.1
tetraspanin 5
chr2_-_219925189 0.48 ENST00000295731.6
indian hedgehog
chr11_-_327537 0.45 ENST00000602735.1
interferon induced transmembrane protein 3
chr17_+_19030782 0.43 ENST00000344415.4
ENST00000577213.1
GRB2-related adaptor protein-like
chr12_+_113376157 0.43 ENST00000228928.7
2'-5'-oligoadenylate synthetase 3, 100kDa
chr13_-_96329048 0.43 ENST00000606011.1
ENST00000499499.2
DNAJC3 antisense RNA 1 (head to head)
chr12_-_93323013 0.42 ENST00000322349.8
early endosome antigen 1
chr2_+_132286754 0.42 ENST00000434330.1
coiled-coil domain containing 74A
chr20_+_19738300 0.40 ENST00000432334.1
RP1-122P22.2
chr16_+_69600058 0.39 ENST00000393742.2
nuclear factor of activated T-cells 5, tonicity-responsive
chr12_+_113376249 0.38 ENST00000551007.1
ENST00000548514.1
2'-5'-oligoadenylate synthetase 3, 100kDa
chr4_-_76008706 0.33 ENST00000562355.1
ENST00000563602.1
RP11-44F21.5
chr8_-_12612962 0.33 ENST00000398246.3
LON peptidase N-terminal domain and ring finger 1
chr17_-_18950310 0.31 ENST00000573099.1
GRB2-related adaptor protein
chr4_+_6784401 0.31 ENST00000425103.1
ENST00000307659.5
KIAA0232
chr16_+_69600209 0.31 ENST00000566899.1
nuclear factor of activated T-cells 5, tonicity-responsive
chr12_+_54519842 0.29 ENST00000508564.1
RP11-834C11.4
chr15_+_57210818 0.28 ENST00000438423.2
ENST00000267811.5
ENST00000452095.2
ENST00000559609.1
ENST00000333725.5
transcription factor 12
chr3_-_128212016 0.28 ENST00000498200.1
ENST00000341105.2
GATA binding protein 2
chr2_-_241759622 0.28 ENST00000320389.7
ENST00000498729.2
kinesin family member 1A
chr1_-_247094628 0.26 ENST00000366508.1
ENST00000326225.3
ENST00000391829.2
AT hook containing transcription factor 1
chr5_+_41904431 0.25 ENST00000381647.2
chromosome 5 open reading frame 51
chr2_+_120517174 0.24 ENST00000263708.2
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr9_+_34992846 0.23 ENST00000443266.1
DnaJ (Hsp40) homolog, subfamily B, member 5
chr13_+_96329381 0.23 ENST00000602402.1
ENST00000376795.6
DnaJ (Hsp40) homolog, subfamily C, member 3
chr11_-_64511575 0.22 ENST00000431822.1
ENST00000377486.3
ENST00000394432.3
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr1_-_200379180 0.22 ENST00000294740.3
zinc finger protein 281
chr1_+_173446405 0.22 ENST00000340385.5
peroxiredoxin 6
chr11_-_62437486 0.22 ENST00000528115.1
chromosome 11 open reading frame 48
chr6_+_36973406 0.21 ENST00000274963.8
FYVE, RhoGEF and PH domain containing 2
chr2_-_9143786 0.21 ENST00000462696.1
ENST00000305997.3
membrane bound O-acyltransferase domain containing 2
chr10_-_12084770 0.21 ENST00000357604.5
UPF2 regulator of nonsense transcripts homolog (yeast)
chr4_+_120133791 0.21 ENST00000274030.6
ubiquitin specific peptidase 53
chr1_+_204494618 0.20 ENST00000367180.1
ENST00000391947.2
Mdm4 p53 binding protein homolog (mouse)
chr3_-_113775328 0.20 ENST00000483766.1
ENST00000545063.1
ENST00000491000.1
ENST00000295878.3
KIAA1407
chr1_+_204797749 0.20 ENST00000367172.4
ENST00000367171.4
ENST00000367170.4
ENST00000338515.6
ENST00000339876.6
ENST00000338586.6
ENST00000539706.1
ENST00000360049.4
ENST00000367169.4
ENST00000446412.1
ENST00000403080.1
neurofascin
chr11_+_10326918 0.20 ENST00000528544.1
adrenomedullin
chr15_+_42694573 0.19 ENST00000397200.4
ENST00000569827.1
calpain 3, (p94)
chr11_-_8954491 0.19 ENST00000526227.1
ENST00000525780.1
ENST00000326053.5
chromosome 11 open reading frame 16
chr11_-_64612041 0.19 ENST00000342711.5
CDC42 binding protein kinase gamma (DMPK-like)
chr1_-_166136187 0.19 ENST00000338353.3
family with sequence similarity 78, member B
chr1_-_166135952 0.18 ENST00000354422.3
family with sequence similarity 78, member B
chr17_+_68165657 0.18 ENST00000243457.3
potassium inwardly-rectifying channel, subfamily J, member 2
chr4_-_174255536 0.18 ENST00000446922.2
high mobility group box 2
chr16_-_46864955 0.18 ENST00000565112.1
chromosome 16 open reading frame 87
chr15_+_57210961 0.18 ENST00000557843.1
transcription factor 12
chr11_+_118826999 0.17 ENST00000264031.2
uroplakin 2
chr17_-_6554877 0.17 ENST00000225728.3
ENST00000575197.1
mediator complex subunit 31
chr14_+_96829814 0.16 ENST00000555181.1
ENST00000553699.1
ENST00000554182.1
GSK3B interacting protein
chr1_-_200379104 0.16 ENST00000367352.3
zinc finger protein 281
chr9_+_19408999 0.15 ENST00000340967.2
alkaline ceramidase 2
chr3_+_14219858 0.15 ENST00000306024.3
LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr11_-_112034803 0.14 ENST00000528832.1
interleukin 18 (interferon-gamma-inducing factor)
chr18_+_77155942 0.14 ENST00000397790.2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr2_+_120302055 0.13 ENST00000598644.1
Primary ciliary dyskinesia protein 1
chr10_+_94821021 0.13 ENST00000285949.5
cytochrome P450, family 26, subfamily C, polypeptide 1
chr11_-_112034780 0.13 ENST00000524595.1
interleukin 18 (interferon-gamma-inducing factor)
chr13_-_99738867 0.13 ENST00000427887.1
dedicator of cytokinesis 9
chr15_-_57210769 0.13 ENST00000559000.1
zinc finger protein 280D
chr15_-_65477637 0.13 ENST00000300107.3
caseinolytic mitochondrial matrix peptidase chaperone subunit
chr11_-_112034831 0.12 ENST00000280357.7
interleukin 18 (interferon-gamma-inducing factor)
chr13_+_50202435 0.12 ENST00000282026.1
ADP-ribosylation factor-like 11
chr4_-_174256276 0.12 ENST00000296503.5
high mobility group box 2
chr10_-_97175444 0.12 ENST00000486141.2
sorbin and SH3 domain containing 1
chr2_-_21266816 0.11 ENST00000399256.4
apolipoprotein B
chr19_+_39904168 0.11 ENST00000438123.1
ENST00000409797.2
ENST00000451354.2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr19_+_49866851 0.11 ENST00000221498.2
ENST00000596402.1
dickkopf-like 1
chr17_+_68071389 0.11 ENST00000283936.1
ENST00000392671.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr1_+_29213678 0.11 ENST00000347529.3
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr2_+_235860690 0.11 ENST00000416021.1
SH3-domain binding protein 4
chr1_-_200379129 0.10 ENST00000367353.1
zinc finger protein 281
chr1_-_33647267 0.10 ENST00000291416.5
tripartite motif containing 62
chr3_-_128902729 0.09 ENST00000451728.2
ENST00000446936.2
ENST00000502976.1
ENST00000500450.2
ENST00000441626.2
CCHC-type zinc finger, nucleic acid binding protein
chr11_-_64703354 0.09 ENST00000532246.1
ENST00000279168.2
glycoprotein hormone alpha 2
chr4_-_174255400 0.09 ENST00000506267.1
high mobility group box 2
chr5_-_93077293 0.09 ENST00000510627.4
POU domain class 5, transcription factor 2
chr3_-_118753716 0.09 ENST00000393775.2
immunoglobulin superfamily, member 11
chr3_-_118753626 0.08 ENST00000489689.1
immunoglobulin superfamily, member 11
chr3_-_128902759 0.08 ENST00000422453.2
ENST00000504813.1
ENST00000512338.1
CCHC-type zinc finger, nucleic acid binding protein
chr20_-_31071309 0.08 ENST00000326071.4
chromosome 20 open reading frame 112
chr3_+_50229037 0.08 ENST00000232461.3
ENST00000433068.1
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
chr2_+_177025619 0.08 ENST00000410016.1
homeobox D3
chr17_-_48207115 0.08 ENST00000511964.1
sterile alpha motif domain containing 14
chr12_-_53228079 0.08 ENST00000330553.5
keratin 79
chr9_-_92051391 0.07 ENST00000420681.2
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr17_-_39674668 0.07 ENST00000393981.3
keratin 15
chr19_+_5681153 0.07 ENST00000579559.1
ENST00000577222.1
hydroxysteroid (11-beta) dehydrogenase 1-like
ribosomal protein L36
chr11_-_7041466 0.07 ENST00000536068.1
ENST00000278314.4
zinc finger protein 214
chr14_+_96671016 0.07 ENST00000542454.2
ENST00000554311.1
ENST00000306005.3
ENST00000539359.1
ENST00000553811.1
bradykinin receptor B2
Uncharacterized protein
chr8_-_100905363 0.07 ENST00000524245.1
cytochrome c oxidase subunit VIc
chr18_+_77155856 0.07 ENST00000253506.5
ENST00000591814.1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chrX_-_134232630 0.07 ENST00000535837.1
ENST00000433425.2
long intergenic non-protein coding RNA 87
chr10_+_69644404 0.06 ENST00000212015.6
sirtuin 1
chr11_-_9113093 0.06 ENST00000450649.2
signal peptide, CUB domain, EGF-like 2
chr3_+_113775576 0.06 ENST00000485050.1
ENST00000281273.4
queuine tRNA-ribosyltransferase domain containing 1
chr10_-_120938303 0.06 ENST00000356951.3
ENST00000298510.2
peroxiredoxin 3
chr6_+_32937083 0.06 ENST00000456339.1
bromodomain containing 2
chr5_-_107717058 0.06 ENST00000359660.5
F-box and leucine-rich repeat protein 17
chrX_-_17878827 0.06 ENST00000360011.1
retinoic acid induced 2
chr19_+_5681011 0.05 ENST00000581893.1
ENST00000411793.2
ENST00000301382.4
ENST00000581773.1
ENST00000423665.2
ENST00000583928.1
ENST00000342970.2
ENST00000422535.2
ENST00000581521.1
ENST00000339423.2
hydroxysteroid (11-beta) dehydrogenase 1-like
chr11_-_9113137 0.05 ENST00000520467.1
ENST00000309263.3
ENST00000457346.2
signal peptide, CUB domain, EGF-like 2
chr16_-_46865286 0.05 ENST00000285697.4
chromosome 16 open reading frame 87
chr4_-_99578789 0.05 ENST00000511651.1
ENST00000505184.1
tetraspanin 5
chr1_-_51425902 0.05 ENST00000396153.2
Fas (TNFRSF6) associated factor 1
chr12_+_81471816 0.05 ENST00000261206.3
acyl-CoA synthetase short-chain family member 3
chr3_+_140947563 0.05 ENST00000505013.1
acid phosphatase-like 2
chr20_+_44035847 0.05 ENST00000372712.2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr6_-_28303901 0.05 ENST00000439158.1
ENST00000446474.1
ENST00000414431.1
ENST00000344279.6
ENST00000453745.1
zinc finger and SCAN domain containing 31
chr11_+_327171 0.05 ENST00000534483.1
ENST00000524824.1
ENST00000531076.1
RP11-326C3.12
chr1_+_63788730 0.04 ENST00000371116.2
forkhead box D3
chr13_-_37633567 0.04 ENST00000464744.1
suppressor of Ty 20 homolog (S. cerevisiae)
chr6_-_56707943 0.04 ENST00000370769.4
ENST00000421834.2
ENST00000312431.6
ENST00000361203.3
ENST00000523817.1
dystonin
chr1_+_156119798 0.04 ENST00000355014.2
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr4_-_120133661 0.04 ENST00000503243.1
ENST00000326780.3
Uncharacterized protein
chr19_+_49866331 0.04 ENST00000597873.1
dickkopf-like 1
chr8_+_86157699 0.04 ENST00000321764.3
carbonic anhydrase XIII
chr11_-_62473706 0.03 ENST00000403550.1
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr11_+_7041677 0.03 ENST00000299481.4
NLR family, pyrin domain containing 14
chr14_+_73603126 0.03 ENST00000557356.1
ENST00000556864.1
ENST00000556533.1
ENST00000556951.1
ENST00000557293.1
ENST00000553719.1
ENST00000553599.1
ENST00000556011.1
ENST00000394157.3
ENST00000357710.4
ENST00000324501.5
ENST00000560005.2
ENST00000555254.1
ENST00000261970.3
ENST00000344094.3
ENST00000554131.1
ENST00000557037.1
presenilin 1
chr17_+_68071458 0.03 ENST00000589377.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr1_+_12123463 0.03 ENST00000417814.2
tumor necrosis factor receptor superfamily, member 8
chr12_+_50451462 0.02 ENST00000447966.2
acid-sensing (proton-gated) ion channel 1
chr11_-_68671264 0.02 ENST00000362034.2
mitochondrial ribosomal protein L21
chr1_+_12123414 0.02 ENST00000263932.2
tumor necrosis factor receptor superfamily, member 8
chr19_-_5680891 0.02 ENST00000309324.4
chromosome 19 open reading frame 70
chrX_+_56259316 0.02 ENST00000468660.1
Kruppel-like factor 8
chr1_-_155948218 0.02 ENST00000313667.4
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr20_+_4666882 0.02 ENST00000379440.4
ENST00000430350.2
prion protein
chr12_+_8185288 0.02 ENST00000162391.3
forkhead box J2
chr11_-_6790286 0.02 ENST00000338569.2
olfactory receptor, family 2, subfamily AG, member 2
chr6_-_28304152 0.02 ENST00000435857.1
zinc finger and SCAN domain containing 31
chr16_+_31225337 0.02 ENST00000322122.3
tripartite motif containing 72
chr3_-_118753566 0.01 ENST00000491903.1
immunoglobulin superfamily, member 11
chr17_-_62340581 0.01 ENST00000258991.3
ENST00000583738.1
ENST00000584379.1
testis expressed 2
chr4_+_75858318 0.01 ENST00000307428.7
prostate androgen-regulated mucin-like protein 1
chrX_-_47479246 0.01 ENST00000295987.7
ENST00000340666.4
synapsin I
chr11_-_64511789 0.01 ENST00000419843.1
ENST00000394430.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr11_+_8932654 0.01 ENST00000299576.5
ENST00000309377.4
ENST00000309357.4
A kinase (PRKA) interacting protein 1
chr1_-_1822495 0.01 ENST00000378609.4
guanine nucleotide binding protein (G protein), beta polypeptide 1
chr11_-_68671244 0.00 ENST00000567045.1
ENST00000450904.2
mitochondrial ribosomal protein L21
chr11_+_57531292 0.00 ENST00000524579.1
catenin (cadherin-associated protein), delta 1
chr16_-_74734742 0.00 ENST00000308807.7
ENST00000573267.1
mixed lineage kinase domain-like
chr3_+_113775594 0.00 ENST00000479882.1
ENST00000493014.1
queuine tRNA-ribosyltransferase domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF350

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.1 0.4 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
0.1 0.3 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.1 0.8 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.0 0.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.4 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.2 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058) positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0 0.2 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.0 0.1 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.0 0.2 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.2 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.1 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0 0.2 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.0 GO:0032759 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.0 0.1 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.7 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.5 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.5 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.1 GO:0050917 sensory perception of umami taste(GO:0050917)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.1 0.8 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0071633 dihydroceramidase activity(GO:0071633)
0.0 0.1 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.5 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0004947 bradykinin receptor activity(GO:0004947)
0.0 0.1 GO:0032129 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.0 0.2 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.1 GO:0000035 acyl binding(GO:0000035)
0.0 0.3 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling