Motif ID: Alx4

Z-value: 0.580


Transcription factors associated with Alx4:

Gene SymbolEntrez IDGene Name
Alx4 ENSMUSG00000040310.6 Alx4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Alx4mm10_v2_chr2_+_93642307_93642388-0.261.1e-01Click!


Activity profile for motif Alx4.

activity profile for motif Alx4


Sorted Z-values histogram for motif Alx4

Sorted Z-values for motif Alx4



Network of associatons between targets according to the STRING database.



First level regulatory network of Alx4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_73483602 2.568 ENSMUST00000033741.8
ENSMUST00000169489.1
Bgn

biglycan

chr17_+_34969912 2.456 ENSMUST00000173680.1
Gm20481
predicted gene 20481
chr1_+_58210397 2.381 ENSMUST00000040442.5
Aox4
aldehyde oxidase 4
chr7_-_45103747 2.222 ENSMUST00000003512.7
Fcgrt
Fc receptor, IgG, alpha chain transporter
chr10_+_97479470 2.215 ENSMUST00000105287.3
Dcn
decorin
chr2_-_160619971 2.150 ENSMUST00000109473.1
Gm14221
predicted gene 14221
chr13_+_44121167 2.073 ENSMUST00000163056.1
ENSMUST00000159595.1
Gm5083

predicted gene 5083

chr6_+_116650674 1.677 ENSMUST00000067354.5
ENSMUST00000178241.1
8430408G22Rik

RIKEN cDNA 8430408G22 gene

chr11_-_102946688 1.665 ENSMUST00000057849.5
C1ql1
complement component 1, q subcomponent-like 1
chr3_-_57294880 1.597 ENSMUST00000171384.1
Tm4sf1
transmembrane 4 superfamily member 1
chr18_+_57468478 1.448 ENSMUST00000091892.2
Ctxn3
cortexin 3
chr8_+_94152607 1.433 ENSMUST00000034211.8
Mt3
metallothionein 3
chr5_+_13398688 1.409 ENSMUST00000125629.1
Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr6_-_136875794 1.357 ENSMUST00000032342.1
Mgp
matrix Gla protein
chr2_+_131491764 1.350 ENSMUST00000028806.5
ENSMUST00000110179.2
ENSMUST00000110189.2
ENSMUST00000110182.2
ENSMUST00000110183.2
ENSMUST00000110186.2
ENSMUST00000110188.1
Smox






spermine oxidase






chr7_-_46667375 1.295 ENSMUST00000107669.2
Tph1
tryptophan hydroxylase 1
chr11_+_80183851 1.192 ENSMUST00000017839.2
Rnf135
ring finger protein 135
chr2_+_91257323 1.178 ENSMUST00000111349.2
ENSMUST00000131711.1
Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr1_-_152386589 1.169 ENSMUST00000162371.1
Tsen15
tRNA splicing endonuclease 15 homolog (S. cerevisiae)
chr1_-_155527083 1.154 ENSMUST00000097531.2
Gm5532
predicted gene 5532
chr8_+_23411490 1.131 ENSMUST00000033952.7
Sfrp1
secreted frizzled-related protein 1
chr19_+_55895508 1.035 ENSMUST00000111646.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr19_-_11604828 1.023 ENSMUST00000025582.4
Ms4a6d
membrane-spanning 4-domains, subfamily A, member 6D
chr1_-_152386675 1.019 ENSMUST00000015124.8
Tsen15
tRNA splicing endonuclease 15 homolog (S. cerevisiae)
chr11_+_58171648 0.967 ENSMUST00000020820.1
Mrpl22
mitochondrial ribosomal protein L22
chr1_-_163725123 0.930 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr3_-_116712644 0.929 ENSMUST00000029569.2
Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chrM_+_8600 0.926 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr4_-_118489755 0.911 ENSMUST00000184261.1
Tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr2_-_29787622 0.908 ENSMUST00000177467.1
ENSMUST00000113807.3
Trub2

TruB pseudouridine (psi) synthase homolog 2 (E. coli)

chr3_+_142620596 0.903 ENSMUST00000165774.1
Gbp2
guanylate binding protein 2
chr3_-_36475688 0.902 ENSMUST00000029266.8
Anxa5
annexin A5
chr8_-_84662841 0.896 ENSMUST00000060427.4
Ier2
immediate early response 2
chr5_-_62766153 0.880 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr6_+_145934113 0.879 ENSMUST00000032383.7
Sspn
sarcospan
chr9_+_80165079 0.871 ENSMUST00000184480.1
Myo6
myosin VI
chr5_-_138170992 0.852 ENSMUST00000139983.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr10_-_81407641 0.850 ENSMUST00000140916.1
Nfic
nuclear factor I/C
chr6_-_101377342 0.795 ENSMUST00000151175.1
Pdzrn3
PDZ domain containing RING finger 3
chr11_+_116843278 0.791 ENSMUST00000106370.3
Mettl23
methyltransferase like 23
chr2_+_125136692 0.786 ENSMUST00000099452.2
Ctxn2
cortexin 2
chr17_+_66111605 0.784 ENSMUST00000116556.2
Wash
WAS protein family homolog
chr15_+_97964220 0.781 ENSMUST00000064200.7
Tmem106c
transmembrane protein 106C
chr9_+_92457369 0.736 ENSMUST00000034941.7
Plscr4
phospholipid scramblase 4
chr14_-_66124482 0.732 ENSMUST00000070515.1
Ephx2
epoxide hydrolase 2, cytoplasmic
chr4_+_122996035 0.730 ENSMUST00000030407.7
Mycl
v-myc myelocytomatosis viral oncogene homolog, lung carcinoma derived (avian)
chr5_+_143370092 0.716 ENSMUST00000120825.1
Grid2ip
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 1
chr17_+_66111529 0.713 ENSMUST00000072383.6
Wash
WAS protein family homolog
chr4_+_105789869 0.696 ENSMUST00000184254.1
Gm12728
predicted gene 12728
chr2_-_5063996 0.680 ENSMUST00000114996.1
Optn
optineurin
chr7_-_142656018 0.679 ENSMUST00000178921.1
Igf2
insulin-like growth factor 2
chr19_+_5088534 0.676 ENSMUST00000025811.4
Yif1a
Yip1 interacting factor homolog A (S. cerevisiae)
chr7_-_46672537 0.672 ENSMUST00000049298.7
Tph1
tryptophan hydroxylase 1
chr4_+_122995944 0.660 ENSMUST00000106252.2
Mycl
v-myc myelocytomatosis viral oncogene homolog, lung carcinoma derived (avian)
chr7_+_19361207 0.659 ENSMUST00000047621.7
Ppp1r13l
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chr2_+_144270900 0.655 ENSMUST00000028910.2
ENSMUST00000110027.1
Mgme1

mitochondrial genome maintainance exonuclease 1

chr14_+_24490678 0.654 ENSMUST00000169826.1
ENSMUST00000112384.3
Rps24

ribosomal protein S24

chr17_-_36032682 0.641 ENSMUST00000102678.4
H2-T23
histocompatibility 2, T region locus 23
chr5_-_43981757 0.620 ENSMUST00000061299.7
Fgfbp1
fibroblast growth factor binding protein 1
chr19_+_5474681 0.615 ENSMUST00000165485.1
ENSMUST00000166253.1
ENSMUST00000167371.1
ENSMUST00000167855.1
ENSMUST00000070118.7
Efemp2




epidermal growth factor-containing fibulin-like extracellular matrix protein 2




chr2_-_150255591 0.611 ENSMUST00000063463.5
Gm21994
predicted gene 21994
chr1_-_72284248 0.602 ENSMUST00000097698.4
ENSMUST00000027381.6
Pecr

peroxisomal trans-2-enoyl-CoA reductase

chr5_-_138171216 0.600 ENSMUST00000147920.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr6_-_83506895 0.573 ENSMUST00000113888.1
ENSMUST00000014698.3
Dguok

deoxyguanosine kinase

chr12_-_75735729 0.559 ENSMUST00000021450.4
Sgpp1
sphingosine-1-phosphate phosphatase 1
chr16_+_18836573 0.541 ENSMUST00000055413.6
2510002D24Rik
RIKEN cDNA 2510002D24 gene
chrM_+_9452 0.532 ENSMUST00000082411.1
mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chr2_+_32606946 0.529 ENSMUST00000113290.1
St6galnac6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr6_-_87335758 0.517 ENSMUST00000042025.9
Antxr1
anthrax toxin receptor 1
chr2_-_180954620 0.515 ENSMUST00000139929.1
Nkain4
Na+/K+ transporting ATPase interacting 4
chr2_-_5063932 0.514 ENSMUST00000027986.4
Optn
optineurin
chr14_+_54686171 0.514 ENSMUST00000038539.6
1700123O20Rik
RIKEN cDNA 1700123O20 gene
chr11_-_115187321 0.512 ENSMUST00000103038.1
ENSMUST00000103039.1
ENSMUST00000103040.4
Nat9


N-acetyltransferase 9 (GCN5-related, putative)


chr2_-_34826071 0.509 ENSMUST00000113077.1
ENSMUST00000028220.3
Fbxw2

F-box and WD-40 domain protein 2

chr11_+_109543694 0.508 ENSMUST00000106696.1
Arsg
arylsulfatase G
chr2_+_32606979 0.508 ENSMUST00000113289.1
ENSMUST00000095044.3
St6galnac6

ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

chr13_+_76579670 0.507 ENSMUST00000126960.1
ENSMUST00000109583.2
Mctp1

multiple C2 domains, transmembrane 1

chr12_-_80643799 0.500 ENSMUST00000166931.1
Erh
enhancer of rudimentary homolog (Drosophila)
chr10_-_128804353 0.495 ENSMUST00000051011.7
Tmem198b
transmembrane protein 198b
chr9_+_72958785 0.493 ENSMUST00000098567.2
ENSMUST00000034734.8
Dyx1c1

dyslexia susceptibility 1 candidate 1 homolog (human)

chr8_-_106573461 0.493 ENSMUST00000073722.5
Gm10073
predicted pseudogene 10073
chr2_-_155357392 0.493 ENSMUST00000165234.1
ENSMUST00000077626.6
Pigu

phosphatidylinositol glycan anchor biosynthesis, class U

chr14_-_118237016 0.491 ENSMUST00000170662.1
Sox21
SRY-box containing gene 21
chr12_+_38783503 0.476 ENSMUST00000159334.1
Etv1
ets variant gene 1
chr11_+_102189620 0.471 ENSMUST00000070334.3
ENSMUST00000078975.7
G6pc3

glucose 6 phosphatase, catalytic, 3

chr15_+_9436028 0.471 ENSMUST00000042360.3
Capsl
calcyphosine-like
chr14_+_55560010 0.460 ENSMUST00000147981.1
ENSMUST00000133256.1
Dcaf11

DDB1 and CUL4 associated factor 11

chr18_-_56572888 0.453 ENSMUST00000174518.1
Aldh7a1
aldehyde dehydrogenase family 7, member A1
chr5_-_118155379 0.452 ENSMUST00000049474.7
Fbxw8
F-box and WD-40 domain protein 8
chr12_-_85824506 0.450 ENSMUST00000021676.5
ENSMUST00000142331.1
0610007P14Rik

RIKEN cDNA 0610007P14 gene

chr15_+_102326400 0.445 ENSMUST00000165717.1
Pfdn5
prefoldin 5
chr5_-_138171248 0.443 ENSMUST00000153867.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr1_+_24177610 0.441 ENSMUST00000054588.8
Col9a1
collagen, type IX, alpha 1
chr12_+_16653470 0.441 ENSMUST00000111064.1
Ntsr2
neurotensin receptor 2
chr10_-_81350389 0.440 ENSMUST00000020454.4
ENSMUST00000105324.2
ENSMUST00000154609.2
ENSMUST00000105323.1
Hmg20b



high mobility group 20B



chr11_-_4095344 0.438 ENSMUST00000004868.5
Mtfp1
mitochondrial fission process 1
chr2_+_109917639 0.435 ENSMUST00000046548.7
ENSMUST00000111037.2
Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr19_-_41933276 0.433 ENSMUST00000075280.4
ENSMUST00000112123.2
Exosc1

exosome component 1

chr10_-_78352469 0.429 ENSMUST00000138035.1
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr11_+_98026695 0.427 ENSMUST00000092425.4
Rpl19
ribosomal protein L19
chr7_-_137410717 0.423 ENSMUST00000120340.1
ENSMUST00000117404.1
ENSMUST00000068996.6
9430038I01Rik


RIKEN cDNA 9430038I01 gene


chr14_+_55559993 0.418 ENSMUST00000117236.1
Dcaf11
DDB1 and CUL4 associated factor 11
chr6_-_118479237 0.416 ENSMUST00000161170.1
Zfp9
zinc finger protein 9
chr11_+_98026918 0.412 ENSMUST00000017548.6
Rpl19
ribosomal protein L19
chr10_-_81350191 0.411 ENSMUST00000122993.1
Hmg20b
high mobility group 20B
chr4_-_150914401 0.409 ENSMUST00000105675.1
Park7
Parkinson disease (autosomal recessive, early onset) 7
chr7_-_126676428 0.408 ENSMUST00000106373.1
Sult1a1
sulfotransferase family 1A, phenol-preferring, member 1
chr9_-_55512156 0.405 ENSMUST00000034866.8
Etfa
electron transferring flavoprotein, alpha polypeptide
chr17_-_55915870 0.402 ENSMUST00000074828.4
Rpl21-ps6
ribosomal protein L21, pseudogene 6
chr17_-_47834682 0.386 ENSMUST00000066368.6
Mdfi
MyoD family inhibitor
chr10_-_81350305 0.384 ENSMUST00000167481.1
Hmg20b
high mobility group 20B
chr8_+_84689247 0.383 ENSMUST00000109767.2
ENSMUST00000177084.1
ENSMUST00000109768.2
ENSMUST00000152301.2
ENSMUST00000177423.1
Trmt1




tRNA methyltransferase 1




chr10_-_77166545 0.376 ENSMUST00000081654.6
Col18a1
collagen, type XVIII, alpha 1
chr14_+_26119811 0.374 ENSMUST00000173617.1
Duxbl2
doubl homeobox B-like 2
chr7_+_3703979 0.374 ENSMUST00000006496.8
Rps9
ribosomal protein S9
chr1_+_172126750 0.371 ENSMUST00000075895.2
ENSMUST00000111252.3
Pex19

peroxisomal biogenesis factor 19

chr8_-_70510322 0.370 ENSMUST00000140679.1
ENSMUST00000129909.1
ENSMUST00000081940.4
Uba52


ubiquitin A-52 residue ribosomal protein fusion product 1


chr12_-_79007276 0.364 ENSMUST00000056660.6
ENSMUST00000174721.1
Tmem229b

transmembrane protein 229B

chr7_+_24270420 0.354 ENSMUST00000108438.3
Zfp93
zinc finger protein 93
chr17_-_56036546 0.354 ENSMUST00000003268.9
Sh3gl1
SH3-domain GRB2-like 1
chr16_-_35363842 0.351 ENSMUST00000043521.4
Sec22a
SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
chr15_+_81744848 0.339 ENSMUST00000109554.1
Zc3h7b
zinc finger CCCH type containing 7B
chr7_-_30195046 0.337 ENSMUST00000001845.5
Capns1
calpain, small subunit 1
chr2_-_132247747 0.337 ENSMUST00000110163.1
ENSMUST00000180286.1
ENSMUST00000028816.2
Tmem230


transmembrane protein 230


chr6_+_125215551 0.336 ENSMUST00000032487.7
ENSMUST00000100942.2
ENSMUST00000063588.8
Vamp1


vesicle-associated membrane protein 1


chr13_+_90923122 0.333 ENSMUST00000051955.7
Rps23
ribosomal protein S23
chr9_+_102834961 0.326 ENSMUST00000035142.6
Ryk
receptor-like tyrosine kinase
chr9_-_22117123 0.324 ENSMUST00000013966.6
Elof1
elongation factor 1 homolog (ELF1, S. cerevisiae)
chr5_-_63968867 0.323 ENSMUST00000154169.1
Rell1
RELT-like 1
chr15_+_102326369 0.320 ENSMUST00000169637.1
ENSMUST00000165671.1
Pfdn5

prefoldin 5

chr11_+_60537978 0.320 ENSMUST00000044250.3
Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chr7_-_126676357 0.318 ENSMUST00000106371.1
ENSMUST00000106372.3
ENSMUST00000155419.1
Sult1a1


sulfotransferase family 1A, phenol-preferring, member 1


chr10_-_8886033 0.316 ENSMUST00000015449.5
Sash1
SAM and SH3 domain containing 1
chr4_+_110397661 0.315 ENSMUST00000106589.2
ENSMUST00000106587.2
ENSMUST00000106591.1
ENSMUST00000106592.1
Agbl4



ATP/GTP binding protein-like 4



chr2_-_130424673 0.312 ENSMUST00000110277.1
Pced1a
PC-esterase domain containing 1A
chr17_-_15527281 0.305 ENSMUST00000154293.1
ENSMUST00000054450.6
Pdcd2

programmed cell death 2

chr15_-_89591855 0.305 ENSMUST00000094056.5
ENSMUST00000023294.8
Rabl2

RAB, member of RAS oncogene family-like 2

chr16_-_10543028 0.304 ENSMUST00000184863.1
ENSMUST00000038281.5
Dexi

dexamethasone-induced transcript

chr14_-_26170283 0.304 ENSMUST00000100809.4
Plac9b
placenta specific 9b
chr17_-_53867041 0.304 ENSMUST00000061311.7
Mrps36-ps1
mitichondrial ribosomal protein S36, pseudogene 1
chr9_-_123678782 0.299 ENSMUST00000170591.1
ENSMUST00000171647.1
Slc6a20a

solute carrier family 6 (neurotransmitter transporter), member 20A

chr19_+_8735808 0.296 ENSMUST00000049424.9
Wdr74
WD repeat domain 74
chr7_-_19562377 0.296 ENSMUST00000058444.8
Ppp1r37
protein phosphatase 1, regulatory subunit 37
chr9_-_14381242 0.292 ENSMUST00000167549.1
Endod1
endonuclease domain containing 1
chr2_-_73453918 0.291 ENSMUST00000102679.1
Wipf1
WAS/WASL interacting protein family, member 1
chr9_+_21955747 0.276 ENSMUST00000053583.5
Swsap1
SWIM type zinc finger 7 associated protein 1
chr11_+_6291660 0.276 ENSMUST00000101554.2
ENSMUST00000093350.3
Ogdh

oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)

chr17_+_26715644 0.272 ENSMUST00000062519.7
ENSMUST00000144221.1
ENSMUST00000142539.1
ENSMUST00000151681.1
Crebrf



CREB3 regulatory factor



chr9_+_123366921 0.269 ENSMUST00000038863.7
Lars2
leucyl-tRNA synthetase, mitochondrial
chr10_-_128626464 0.267 ENSMUST00000026420.5
Rps26
ribosomal protein S26
chrX_-_23266751 0.266 ENSMUST00000115316.2
Klhl13
kelch-like 13
chr17_+_29274078 0.264 ENSMUST00000149405.2
BC004004
cDNA sequence BC004004
chr12_+_111814170 0.254 ENSMUST00000021714.7
Zfyve21
zinc finger, FYVE domain containing 21
chr11_+_58948890 0.251 ENSMUST00000078267.3
Hist3h2ba
histone cluster 3, H2ba
chr6_+_134640940 0.250 ENSMUST00000062755.8
Loh12cr1
loss of heterozygosity, 12, chromosomal region 1 homolog (human)
chr16_+_11406618 0.249 ENSMUST00000122168.1
Snx29
sorting nexin 29
chr15_-_83350151 0.245 ENSMUST00000067215.7
Arfgap3
ADP-ribosylation factor GTPase activating protein 3
chr13_+_67833235 0.241 ENSMUST00000060609.7
Gm10037
predicted gene 10037
chr14_-_59365410 0.241 ENSMUST00000161031.1
ENSMUST00000160425.1
Phf11d

PHD finger protein 11D

chr8_+_31150307 0.240 ENSMUST00000098842.2
Tti2
TELO2 interacting protein 2
chr17_-_57031468 0.235 ENSMUST00000007814.8
Khsrp
KH-type splicing regulatory protein
chr7_-_29155597 0.235 ENSMUST00000123416.1
Fam98c
family with sequence similarity 98, member C
chr4_-_14621669 0.235 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr8_+_84689308 0.230 ENSMUST00000125370.3
ENSMUST00000175784.1
Trmt1

tRNA methyltransferase 1

chr5_-_114773372 0.228 ENSMUST00000112183.1
ENSMUST00000086564.4
Git2

G protein-coupled receptor kinase-interactor 2

chr5_-_3647806 0.227 ENSMUST00000119783.1
ENSMUST00000007559.8
Gatad1

GATA zinc finger domain containing 1

chr10_-_62379852 0.225 ENSMUST00000143236.1
ENSMUST00000133429.1
ENSMUST00000132926.1
ENSMUST00000116238.2
Hk1



hexokinase 1



chr5_-_140702241 0.221 ENSMUST00000077890.5
ENSMUST00000041783.7
ENSMUST00000142081.1
Iqce


IQ motif containing E


chr10_-_86022325 0.221 ENSMUST00000181665.1
A230060F14Rik
RIKEN cDNA A230060F14 gene
chr1_+_190928492 0.221 ENSMUST00000066632.7
ENSMUST00000110899.1
Angel2

angel homolog 2 (Drosophila)

chr3_+_27938638 0.220 ENSMUST00000120834.1
Pld1
phospholipase D1
chr11_-_115419917 0.214 ENSMUST00000106537.1
ENSMUST00000043931.2
ENSMUST00000073791.3
Atp5h


ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d


chr14_-_69707546 0.210 ENSMUST00000118374.1
R3hcc1
R3H domain and coiled-coil containing 1
chr7_+_129591859 0.209 ENSMUST00000084519.5
Wdr11
WD repeat domain 11
chr15_-_79774408 0.209 ENSMUST00000023055.6
Dnal4
dynein, axonemal, light chain 4
chr9_-_71163224 0.207 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr5_+_48242549 0.206 ENSMUST00000172493.1
Slit2
slit homolog 2 (Drosophila)
chr5_+_115279666 0.203 ENSMUST00000040421.4
Coq5
coenzyme Q5 homolog, methyltransferase (yeast)
chr4_+_20007938 0.202 ENSMUST00000125799.1
ENSMUST00000121491.1
Ttpa

tocopherol (alpha) transfer protein

chr16_-_45724600 0.199 ENSMUST00000096057.4
Tagln3
transgelin 3
chr14_+_25980039 0.199 ENSMUST00000173155.1
Duxbl1
double homeobox B-like 1
chr14_-_69707493 0.194 ENSMUST00000121142.1
R3hcc1
R3H domain and coiled-coil containing 1
chr8_+_64947177 0.194 ENSMUST00000079896.7
ENSMUST00000026595.5
Tmem192

transmembrane protein 192

chr7_-_30559600 0.193 ENSMUST00000043975.4
ENSMUST00000156241.1
Lin37

lin-37 homolog (C. elegans)

chr7_+_127233227 0.193 ENSMUST00000056232.6
Zfp553
zinc finger protein 553
chr10_+_18845071 0.192 ENSMUST00000019998.7
Perp
PERP, TP53 apoptosis effector
chr5_-_151651216 0.190 ENSMUST00000038131.9
Rfc3
replication factor C (activator 1) 3
chr5_-_114823460 0.187 ENSMUST00000140374.1
ENSMUST00000100850.4
Gm20499
2610524H06Rik
predicted gene 20499
RIKEN cDNA 2610524H06 gene
chr11_-_115276973 0.184 ENSMUST00000021078.2
Fdxr
ferredoxin reductase
chr9_+_22475867 0.178 ENSMUST00000128812.1
Bbs9
Bardet-Biedl syndrome 9 (human)
chr11_-_51606840 0.177 ENSMUST00000074669.3
ENSMUST00000101249.2
ENSMUST00000109103.3
Hnrnpab


heterogeneous nuclear ribonucleoprotein A/B


chr4_-_14621805 0.176 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr10_+_80798652 0.174 ENSMUST00000151928.1
Sf3a2
splicing factor 3a, subunit 2
chr5_-_114773488 0.172 ENSMUST00000178440.1
ENSMUST00000043283.7
ENSMUST00000112185.2
Git2


G protein-coupled receptor kinase-interactor 2


chr8_-_119778380 0.172 ENSMUST00000049156.5
Tldc1
TBC/LysM associated domain containing 1
chr10_-_80798476 0.171 ENSMUST00000036805.5
Plekhj1
pleckstrin homology domain containing, family J member 1
chr9_-_123678873 0.166 ENSMUST00000040960.6
Slc6a20a
solute carrier family 6 (neurotransmitter transporter), member 20A
chr3_-_67515487 0.164 ENSMUST00000178314.1
ENSMUST00000054825.4
Rarres1

retinoic acid receptor responder (tazarotene induced) 1

chr2_-_144270852 0.160 ENSMUST00000110030.3
Snx5
sorting nexin 5
chr15_-_79774383 0.159 ENSMUST00000069877.5
Dnal4
dynein, axonemal, light chain 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0046110 xanthine metabolic process(GO:0046110)
0.6 1.1 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.5 4.8 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.5 1.4 GO:0097212 lysosomal membrane organization(GO:0097212)
0.4 1.7 GO:0061743 motor learning(GO:0061743)
0.3 1.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.3 0.6 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.3 1.4 GO:0021856 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.3 1.4 GO:0046208 spermine catabolic process(GO:0046208)
0.3 0.5 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.2 2.0 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.2 0.7 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) olefin metabolic process(GO:1900673)
0.2 0.9 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.2 0.6 GO:2000564 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.2 0.6 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.2 1.9 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.2 0.9 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.2 0.5 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2 2.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 0.4 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.1 0.6 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.1 1.5 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1 0.4 GO:0050787 glycolate metabolic process(GO:0009441) enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) detoxification of mercury ion(GO:0050787) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
0.1 1.0 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 1.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.3 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 0.6 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.7 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.1 0.4 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 1.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 0.7 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.2 GO:0021886 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.1 0.5 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.3 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.1 0.3 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.1 0.3 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.1 0.2 GO:0021972 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.1 0.7 GO:0051923 sulfation(GO:0051923)
0.1 0.9 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.1 0.4 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.1 0.4 GO:0019532 oxalate transport(GO:0019532)
0.1 0.3 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.1 0.9 GO:0044406 adhesion of symbiont to host(GO:0044406)
0.1 0.2 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.1 0.2 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 1.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.5 GO:0015838 proline transport(GO:0015824) amino-acid betaine transport(GO:0015838)
0.0 0.5 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.7 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.3 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.3 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.5 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.6 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.9 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.7 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.2 GO:0046689 response to mercury ion(GO:0046689)
0.0 0.4 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.9 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.2 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.2 GO:0002934 desmosome organization(GO:0002934)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.2 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.3 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.4 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.5 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.4 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.2 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.4 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.3 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.4 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.0 GO:0072319 vesicle uncoating(GO:0072319)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.2 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.4 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 1.4 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 0.6 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 0.5 GO:0071384 cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.0 0.4 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.3 GO:0018126 protein hydroxylation(GO:0018126)
0.0 0.2 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.0 0.1 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.2 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.3 GO:0001825 blastocyst formation(GO:0001825)
0.0 0.7 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.1 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0044301 climbing fiber(GO:0044301)
0.3 1.2 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.2 0.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 1.9 GO:0042555 MCM complex(GO:0042555)
0.1 2.2 GO:0098644 complex of collagen trimers(GO:0098644)
0.1 1.0 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.4 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 0.4 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.1 0.5 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.5 GO:1990393 3M complex(GO:1990393)
0.1 0.9 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.1 0.7 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.3 GO:0070820 tertiary granule(GO:0070820)
0.1 0.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 0.6 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.9 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.5 GO:0034709 methylosome(GO:0034709)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.9 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 1.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 1.4 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.9 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.3 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 4.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.6 GO:0009986 cell surface(GO:0009986)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.7 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.9 GO:0014704 intercalated disc(GO:0014704)
0.0 0.2 GO:0097228 sperm principal piece(GO:0097228)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.6 2.4 GO:0030151 molybdenum ion binding(GO:0030151)
0.5 1.4 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.4 2.2 GO:0019770 IgG receptor activity(GO:0019770)
0.4 2.2 GO:0000213 tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.2 0.7 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.2 1.2 GO:1990932 5.8S rRNA binding(GO:1990932)
0.2 0.6 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1 1.0 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.7 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 0.6 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.4 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.1 1.2 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.1 0.6 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.5 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.1 0.7 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.1 1.4 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.5 GO:0034235 GPI anchor binding(GO:0034235)
0.1 5.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 1.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 0.7 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.6 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 0.3 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 1.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.5 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 0.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.3 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.1 0.9 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.2 GO:0015254 glycerol channel activity(GO:0015254)
0.0 1.0 GO:0070016 gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.0 0.5 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.0 1.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 1.9 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.2 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.4 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.9 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 1.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.4 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.0 0.5 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.4 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.8 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.8 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.4 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.9 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0043142 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 0.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 2.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.4 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.9 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 0.3 GO:0000993 RNA polymerase II core binding(GO:0000993)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.8 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.1 PID_ATR_PATHWAY ATR signaling pathway
0.0 1.4 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 4.0 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.2 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.5 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 0.6 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.1 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.9 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.9 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.4 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.0 1.0 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.7 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.7 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.9 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.5 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.3 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.4 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 0.8 PID_P73PATHWAY p73 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.8 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.2 2.0 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 1.9 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.1 0.7 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.5 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.4 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.2 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 0.5 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 0.4 REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.9 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.0 0.7 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.6 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 1.6 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.0 REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.2 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.9 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.7 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.2 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.9 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.6 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.7 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 0.5 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.1 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.6 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME_POL_SWITCHING Genes involved in Polymerase switching
0.0 0.9 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 0.2 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 0.3 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.5 REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.3 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.6 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.1 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.1 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs