Motif ID: Arnt2

Z-value: 0.316


Transcription factors associated with Arnt2:

Gene SymbolEntrez IDGene Name
Arnt2 ENSMUSG00000015709.8 Arnt2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Arnt2mm10_v2_chr7_-_84409959_844100020.192.4e-01Click!


Activity profile for motif Arnt2.

activity profile for motif Arnt2


Sorted Z-values histogram for motif Arnt2

Sorted Z-values for motif Arnt2



Network of associatons between targets according to the STRING database.



First level regulatory network of Arnt2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_46890405 1.292 ENSMUST00000086675.3
 A330017A19Rik
RIKEN cDNA A330017A19 gene
chr7_+_130865756 1.125 ENSMUST00000120441.1
 Plekha1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr7_+_130865835 0.958 ENSMUST00000075181.4
ENSMUST00000048180.5
 Plekha1

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1

chr9_-_86695897 0.938 ENSMUST00000034989.8
 Me1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr2_+_5951440 0.850 ENSMUST00000060092.6
 Upf2
UPF2 regulator of nonsense transcripts homolog (yeast)
chr13_+_13590402 0.764 ENSMUST00000110559.1
 Lyst
lysosomal trafficking regulator
chr13_+_118714678 0.732 ENSMUST00000022246.8
 Fgf10
fibroblast growth factor 10
chr1_+_87327008 0.697 ENSMUST00000172794.1
ENSMUST00000164992.2
 Gigyf2

GRB10 interacting GYF protein 2

chr4_+_101496648 0.684 ENSMUST00000106930.1
ENSMUST00000154120.1
 Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr1_+_87327044 0.596 ENSMUST00000173173.1
 Gigyf2
GRB10 interacting GYF protein 2
chr1_+_87326997 0.593 ENSMUST00000027475.8
 Gigyf2
GRB10 interacting GYF protein 2
chr2_-_54085542 0.528 ENSMUST00000100089.2
 Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chr4_+_137862270 0.503 ENSMUST00000130407.1
 Ece1
endothelin converting enzyme 1
chr1_-_52817503 0.458 ENSMUST00000162576.1
 Inpp1
inositol polyphosphate-1-phosphatase
chr1_-_52817643 0.392 ENSMUST00000027271.2
 Inpp1
inositol polyphosphate-1-phosphatase
chr12_-_59011996 0.383 ENSMUST00000021375.5
 Sec23a
SEC23A (S. cerevisiae)
chr18_+_31634368 0.332 ENSMUST00000178164.1
 Sap130
Sin3A associated protein
chr18_+_31634374 0.320 ENSMUST00000025109.7
 Sap130
Sin3A associated protein
chr3_+_69721985 0.304 ENSMUST00000029358.8
 Nmd3
NMD3 homolog (S. cerevisiae)
chr11_+_107547925 0.299 ENSMUST00000100305.1
ENSMUST00000075012.1
ENSMUST00000106746.1
 Helz


helicase with zinc finger domain


chr2_+_59160884 0.278 ENSMUST00000037903.8
 Pkp4
plakophilin 4
chr2_-_33371400 0.263 ENSMUST00000113164.1
ENSMUST00000091039.2
ENSMUST00000042615.6
 Ralgps1


Ral GEF with PH domain and SH3 binding motif 1


chr2_-_33371486 0.260 ENSMUST00000113165.1
 Ralgps1
Ral GEF with PH domain and SH3 binding motif 1
chr1_-_16619245 0.248 ENSMUST00000182984.1
ENSMUST00000182554.1
 Ube2w

ubiquitin-conjugating enzyme E2W (putative)

chr5_-_135251209 0.242 ENSMUST00000062572.2
 Fzd9
frizzled homolog 9 (Drosophila)
chr4_-_48279544 0.235 ENSMUST00000030028.4
 Erp44
endoplasmic reticulum protein 44
chr4_-_123116686 0.229 ENSMUST00000166337.1
 Gm17244
predicted gene, 17244
chr7_-_45370559 0.220 ENSMUST00000003971.7
 Lin7b
lin-7 homolog B (C. elegans)
chr1_+_59912972 0.190 ENSMUST00000036540.5
 Fam117b
family with sequence similarity 117, member B
chr19_-_5098418 0.186 ENSMUST00000025805.6
 Cnih2
cornichon homolog 2 (Drosophila)
chr1_-_58973421 0.173 ENSMUST00000173590.1
ENSMUST00000027186.5
 Trak2

trafficking protein, kinesin binding 2

chr6_+_4601124 0.169 ENSMUST00000181734.1
ENSMUST00000141359.1
 Casd1

CAS1 domain containing 1

chr14_-_63543931 0.153 ENSMUST00000058679.5
 Mtmr9
myotubularin related protein 9
chr18_-_10030017 0.151 ENSMUST00000116669.1
ENSMUST00000092096.6
 Usp14

ubiquitin specific peptidase 14

chr9_+_86695542 0.098 ENSMUST00000150367.2
 A330041J22Rik
RIKEN cDNA A330041J22 gene
chr17_-_65613521 0.094 ENSMUST00000024897.8
 Vapa
vesicle-associated membrane protein, associated protein A
chr2_-_91649785 0.070 ENSMUST00000111333.1
 Zfp408
zinc finger protein 408
chr1_+_58973521 0.067 ENSMUST00000114296.1
ENSMUST00000027185.4
 Stradb

STE20-related kinase adaptor beta

chr8_+_83900706 0.064 ENSMUST00000045393.8
ENSMUST00000132500.1
ENSMUST00000152978.1
 Lphn1


latrophilin 1


chr2_+_14604252 0.054 ENSMUST00000114723.2
 Cacnb2
calcium channel, voltage-dependent, beta 2 subunit
chr2_-_91649751 0.052 ENSMUST00000099714.3
 Zfp408
zinc finger protein 408
chr2_+_119208975 0.041 ENSMUST00000102519.4
 Zfyve19
zinc finger, FYVE domain containing 19
chr19_+_43612299 0.036 ENSMUST00000057178.9
 Nkx2-3
NK2 homeobox 3
chrX_-_53269786 0.029 ENSMUST00000114841.1
ENSMUST00000071023.5
 Fam122b

family with sequence similarity 122, member B

chr15_-_38078842 0.019 ENSMUST00000110336.2
 Ubr5
ubiquitin protein ligase E3 component n-recognin 5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.2 0.7 GO:0071336 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.2 0.9 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.2 0.5 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1 2.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 0.7 GO:0072318 clathrin coat disassembly(GO:0072318)
0.1 0.5 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.1 0.2 GO:1990523 bone regeneration(GO:1990523)
0.1 1.9 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.1 0.2 GO:1901608 regulation of vesicle transport along microtubule(GO:1901608)
0.1 0.3 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.1 0.2 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.8 GO:0031100 organ regeneration(GO:0031100)
0.0 0.9 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828) positive regulation by host of viral genome replication(GO:0044829)
0.0 0.0 GO:0009838 abscission(GO:0009838)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.5 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.7 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 2.1 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0031527 filopodium membrane(GO:0031527)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.2 0.9 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.2 0.7 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.5 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 2.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 1.9 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.8 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.2 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.2 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.1 PID_PI3KCI_PATHWAY Class I PI3K signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.4 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.7 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis