Motif ID: Atf7_E4f1

Z-value: 0.968

Transcription factors associated with Atf7_E4f1:

Gene SymbolEntrez IDGene Name
Atf7 ENSMUSG00000052414.9 Atf7
Atf7 ENSMUSG00000071584.1 Atf7
E4f1 ENSMUSG00000024137.8 E4f1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
E4f1mm10_v2_chr17_-_24455265_24455345-0.401.1e-02Click!
Atf7mm10_v2_chr15_-_102529025_102529025-0.343.1e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Atf7_E4f1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_113619318 12.707 ENSMUST00000146390.2
ENSMUST00000106630.1
Sstr2

somatostatin receptor 2

chr11_+_101468164 7.604 ENSMUST00000001347.6
Rnd2
Rho family GTPase 2
chr15_+_99074968 7.512 ENSMUST00000039665.6
Troap
trophinin associated protein
chr3_-_36571952 7.196 ENSMUST00000029270.3
Ccna2
cyclin A2
chr5_-_106458440 7.041 ENSMUST00000086795.6
Barhl2
BarH-like 2 (Drosophila)
chr3_+_135212557 6.839 ENSMUST00000062893.7
Cenpe
centromere protein E
chr5_-_124032214 6.809 ENSMUST00000040967.7
Vps37b
vacuolar protein sorting 37B (yeast)
chr6_-_23248264 6.388 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr6_+_113531675 6.155 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2

Fanconi anemia, complementation group D2

chr1_+_74791516 5.894 ENSMUST00000006718.8
Wnt10a
wingless related MMTV integration site 10a
chr8_+_116921735 5.727 ENSMUST00000034205.4
Cenpn
centromere protein N
chr2_+_105668888 5.660 ENSMUST00000111086.4
ENSMUST00000111087.3
Pax6

paired box gene 6

chr17_-_71526819 5.476 ENSMUST00000024851.9
Ndc80
NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr17_+_72918298 5.363 ENSMUST00000024857.6
Lbh
limb-bud and heart
chr2_+_105668935 5.115 ENSMUST00000142772.1
Pax6
paired box gene 6
chr4_+_11704439 4.690 ENSMUST00000108304.2
Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chr8_-_84662841 4.288 ENSMUST00000060427.4
Ier2
immediate early response 2
chr11_-_88718223 4.000 ENSMUST00000107909.1
Msi2
musashi RNA-binding protein 2
chr1_-_134079114 3.926 ENSMUST00000020692.6
Btg2
B cell translocation gene 2, anti-proliferative
chr11_-_6444352 3.815 ENSMUST00000093346.5
ENSMUST00000109737.2
H2afv

H2A histone family, member V

chr11_-_78165521 3.607 ENSMUST00000017530.3
Traf4
TNF receptor associated factor 4
chr15_+_25758755 3.528 ENSMUST00000131834.1
ENSMUST00000124966.1
Myo10

myosin X

chr4_-_117182623 3.389 ENSMUST00000065896.2
Kif2c
kinesin family member 2C
chr7_-_118533298 3.361 ENSMUST00000098090.3
ENSMUST00000032887.3
Coq7

demethyl-Q 7

chr3_+_40800054 3.351 ENSMUST00000168287.1
Plk4
polo-like kinase 4
chr2_+_109280738 3.326 ENSMUST00000028527.7
Kif18a
kinesin family member 18A
chr3_+_67374116 3.286 ENSMUST00000061322.8
Mlf1
myeloid leukemia factor 1
chr2_-_127133909 3.271 ENSMUST00000110387.3
Ncaph
non-SMC condensin I complex, subunit H
chr4_-_97584605 3.149 ENSMUST00000107067.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr10_-_128176568 3.148 ENSMUST00000092033.2
Rbms2
RNA binding motif, single stranded interacting protein 2
chr4_-_97584612 3.129 ENSMUST00000107068.2
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr11_-_101551837 3.114 ENSMUST00000017290.4
Brca1
breast cancer 1
chr3_+_67374091 3.099 ENSMUST00000077916.5
Mlf1
myeloid leukemia factor 1
chr15_+_34238026 3.030 ENSMUST00000022867.3
Laptm4b
lysosomal-associated protein transmembrane 4B
chr11_-_100939357 2.982 ENSMUST00000092671.5
ENSMUST00000103114.1
Stat3

signal transducer and activator of transcription 3

chr12_+_102554966 2.947 ENSMUST00000021610.5
Chga
chromogranin A
chr18_+_82914632 2.931 ENSMUST00000071233.6
Zfp516
zinc finger protein 516
chr11_-_100939540 2.890 ENSMUST00000127638.1
Stat3
signal transducer and activator of transcription 3
chr7_+_112679314 2.864 ENSMUST00000084705.5
ENSMUST00000059768.10
Tead1

TEA domain family member 1

chr11_-_100939457 2.846 ENSMUST00000138438.1
Stat3
signal transducer and activator of transcription 3
chr3_+_127553462 2.789 ENSMUST00000043108.4
4930422G04Rik
RIKEN cDNA 4930422G04 gene
chr7_+_112679327 2.762 ENSMUST00000106638.2
Tead1
TEA domain family member 1
chr10_+_96616998 2.658 ENSMUST00000038377.7
Btg1
B cell translocation gene 1, anti-proliferative
chrX_-_60893430 2.632 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr11_-_84525514 2.581 ENSMUST00000018842.7
Lhx1
LIM homeobox protein 1
chr7_-_137314394 2.556 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
Ebf3



early B cell factor 3



chr7_-_144939823 2.546 ENSMUST00000093962.4
Ccnd1
cyclin D1
chr14_+_47472547 2.452 ENSMUST00000168833.1
ENSMUST00000163324.1
ENSMUST00000043112.7
Fbxo34


F-box protein 34


chr11_+_101665541 2.406 ENSMUST00000039388.2
Arl4d
ADP-ribosylation factor-like 4D
chr17_+_36958623 2.373 ENSMUST00000173814.1
Znrd1as
Znrd1 antisense
chr7_+_102441685 2.360 ENSMUST00000033283.9
Rrm1
ribonucleotide reductase M1
chr13_-_23761223 2.330 ENSMUST00000102964.2
Hist1h4a
histone cluster 1, H4a
chr17_+_36958571 2.279 ENSMUST00000040177.6
Znrd1as
Znrd1 antisense
chr19_+_37376359 2.268 ENSMUST00000012587.3
Kif11
kinesin family member 11
chr17_-_26508463 2.257 ENSMUST00000025025.6
Dusp1
dual specificity phosphatase 1
chr17_-_31277327 2.201 ENSMUST00000024832.7
Rsph1
radial spoke head 1 homolog (Chlamydomonas)
chr14_+_47472628 2.190 ENSMUST00000095941.2
Fbxo34
F-box protein 34
chr17_-_36958206 2.185 ENSMUST00000172823.1
Znrd1
zinc ribbon domain containing, 1
chr11_+_84525669 2.148 ENSMUST00000126072.1
ENSMUST00000128121.1
1500016L03Rik

RIKEN cDNA 1500016L03 gene

chr11_+_69324069 2.140 ENSMUST00000060956.6
ENSMUST00000108662.1
Trappc1

trafficking protein particle complex 1

chr1_+_175880775 2.104 ENSMUST00000039725.6
Exo1
exonuclease 1
chr4_+_111720187 2.082 ENSMUST00000084354.3
Spata6
spermatogenesis associated 6
chr11_+_69324055 2.081 ENSMUST00000102601.3
Trappc1
trafficking protein particle complex 1
chr2_-_157007039 2.014 ENSMUST00000103129.2
ENSMUST00000103130.1
Dsn1

DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)

chr13_+_23531044 1.988 ENSMUST00000102972.3
Hist1h4h
histone cluster 1, H4h
chr17_-_36958437 1.978 ENSMUST00000113669.2
Znrd1
zinc ribbon domain containing, 1
chr12_+_79130777 1.974 ENSMUST00000021550.6
Arg2
arginase type II
chr7_+_139389072 1.907 ENSMUST00000106098.1
ENSMUST00000026550.7
Inpp5a

inositol polyphosphate-5-phosphatase A

chr4_+_130107556 1.906 ENSMUST00000030563.5
Pef1
penta-EF hand domain containing 1
chr11_-_88718165 1.896 ENSMUST00000107908.1
Msi2
musashi RNA-binding protein 2
chr11_+_84525647 1.890 ENSMUST00000134800.1
1500016L03Rik
RIKEN cDNA 1500016L03 gene
chr9_+_48495345 1.867 ENSMUST00000048824.7
Gm5617
predicted gene 5617
chr3_+_31095052 1.843 ENSMUST00000118470.1
ENSMUST00000029194.5
ENSMUST00000123532.1
ENSMUST00000117728.1
Skil



SKI-like



chrX_-_7188713 1.832 ENSMUST00000004428.7
Clcn5
chloride channel 5
chr7_+_3703979 1.830 ENSMUST00000006496.8
Rps9
ribosomal protein S9
chr11_-_88718078 1.800 ENSMUST00000092794.5
Msi2
musashi RNA-binding protein 2
chr11_-_69323768 1.798 ENSMUST00000092973.5
Cntrob
centrobin, centrosomal BRCA2 interacting protein
chr2_-_157007015 1.781 ENSMUST00000146413.1
Dsn1
DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
chr7_+_44496588 1.771 ENSMUST00000107927.3
Fam71e1
family with sequence similarity 71, member E1
chr9_-_96478596 1.759 ENSMUST00000071301.4
Rnf7
ring finger protein 7
chr11_+_69323963 1.745 ENSMUST00000102602.1
Trappc1
trafficking protein particle complex 1
chr17_-_36958533 1.728 ENSMUST00000172518.1
Znrd1
zinc ribbon domain containing, 1
chr8_+_92674289 1.696 ENSMUST00000034185.6
Irx6
Iroquois related homeobox 6 (Drosophila)
chr1_+_95313607 1.665 ENSMUST00000059975.6
Fam174a
family with sequence similarity 174, member A
chr12_-_69159109 1.644 ENSMUST00000037023.8
Rps29
ribosomal protein S29
chr4_-_123750236 1.616 ENSMUST00000102636.3
Akirin1
akirin 1
chr2_+_164746028 1.580 ENSMUST00000109327.3
Dnttip1
deoxynucleotidyltransferase, terminal, interacting protein 1
chr17_-_56476462 1.559 ENSMUST00000067538.5
Ptprs
protein tyrosine phosphatase, receptor type, S
chr7_+_3704025 1.534 ENSMUST00000108623.1
ENSMUST00000139818.1
ENSMUST00000108625.1
Rps9


ribosomal protein S9


chr7_+_3704307 1.515 ENSMUST00000108624.1
ENSMUST00000126562.1
Rps9

ribosomal protein S9

chr18_+_11657349 1.511 ENSMUST00000047322.6
Rbbp8
retinoblastoma binding protein 8
chr2_+_102706356 1.508 ENSMUST00000123759.1
ENSMUST00000111212.1
ENSMUST00000005220.4
Slc1a2


solute carrier family 1 (glial high affinity glutamate transporter), member 2


chr3_+_40800013 1.499 ENSMUST00000026858.5
ENSMUST00000170825.1
Plk4

polo-like kinase 4

chr9_-_75409951 1.496 ENSMUST00000049355.10
Mapk6
mitogen-activated protein kinase 6
chr5_+_137630116 1.446 ENSMUST00000175968.1
Lrch4
leucine-rich repeats and calponin homology (CH) domain containing 4
chrX_+_112311334 1.437 ENSMUST00000026599.3
ENSMUST00000113415.1
Apool

apolipoprotein O-like

chr5_+_142960343 1.419 ENSMUST00000031565.8
Fscn1
fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)
chr7_+_82867327 1.415 ENSMUST00000082237.5
Mex3b
mex3 homolog B (C. elegans)
chr10_-_128547722 1.408 ENSMUST00000040572.3
Zc3h10
zinc finger CCCH type containing 10
chr19_+_53529100 1.392 ENSMUST00000038287.6
Dusp5
dual specificity phosphatase 5
chr8_+_72135247 1.374 ENSMUST00000003575.9
Tpm4
tropomyosin 4
chr5_-_5559501 1.374 ENSMUST00000119521.1
Gtpbp10
GTP-binding protein 10 (putative)
chr9_-_96478660 1.362 ENSMUST00000057500.4
Rnf7
ring finger protein 7
chr11_+_64435315 1.326 ENSMUST00000058652.5
Hs3st3a1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr12_+_112620030 1.323 ENSMUST00000180015.1
ENSMUST00000021726.6
Adssl1

adenylosuccinate synthetase like 1

chr3_-_45378206 1.320 ENSMUST00000181047.1
2610316D01Rik
RIKEN cDNA 2610316D01 gene
chr10_+_44268328 1.316 ENSMUST00000039286.4
Atg5
autophagy related 5
chr11_+_60537978 1.314 ENSMUST00000044250.3
Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chr10_+_79682169 1.312 ENSMUST00000020550.5
Cdc34
cell division cycle 34
chr5_-_5559521 1.274 ENSMUST00000088842.4
ENSMUST00000115441.2
Gtpbp10

GTP-binding protein 10 (putative)

chr7_+_44748413 1.263 ENSMUST00000002275.8
Vrk3
vaccinia related kinase 3
chr2_+_155381808 1.236 ENSMUST00000043237.7
ENSMUST00000174685.1
Trp53inp2

transformation related protein 53 inducible nuclear protein 2

chr2_+_164745979 1.213 ENSMUST00000017443.7
ENSMUST00000109326.3
Dnttip1

deoxynucleotidyltransferase, terminal, interacting protein 1

chr9_-_105395237 1.211 ENSMUST00000140851.1
Nek11
NIMA (never in mitosis gene a)-related expressed kinase 11
chr14_-_55681776 1.204 ENSMUST00000007733.6
Tinf2
Terf1 (TRF1)-interacting nuclear factor 2
chr2_-_36136602 1.194 ENSMUST00000122456.1
Rbm18
RNA binding motif protein 18
chr7_+_44748584 1.182 ENSMUST00000171821.1
Vrk3
vaccinia related kinase 3
chr12_-_102878406 1.178 ENSMUST00000045652.6
Btbd7
BTB (POZ) domain containing 7
chr4_+_130360132 1.167 ENSMUST00000105994.3
Snrnp40
small nuclear ribonucleoprotein 40 (U5)
chr2_-_60125651 1.157 ENSMUST00000112550.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr6_+_120836201 1.157 ENSMUST00000009256.2
Bcl2l13
BCL2-like 13 (apoptosis facilitator)
chr4_+_141301228 1.146 ENSMUST00000006614.2
Epha2
Eph receptor A2
chr17_-_27907706 1.142 ENSMUST00000025057.4
Taf11
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr4_-_151057933 1.138 ENSMUST00000030797.3
Vamp3
vesicle-associated membrane protein 3
chr7_+_44748640 1.137 ENSMUST00000165957.1
ENSMUST00000144515.2
Vrk3

vaccinia related kinase 3

chr6_-_30304513 1.135 ENSMUST00000094543.2
ENSMUST00000102993.3
Ube2h

ubiquitin-conjugating enzyme E2H

chr12_+_112644828 1.130 ENSMUST00000021728.4
ENSMUST00000109755.3
Siva1

SIVA1, apoptosis-inducing factor

chrX_-_155216338 1.125 ENSMUST00000112551.3
Sat1
spermidine/spermine N1-acetyl transferase 1
chr6_-_127109517 1.124 ENSMUST00000039913.8
9630033F20Rik
RIKEN cDNA 9630033F20 gene
chr6_-_86669136 1.117 ENSMUST00000001184.7
Mxd1
MAX dimerization protein 1
chr7_-_38271310 1.112 ENSMUST00000032585.6
Pop4
processing of precursor 4, ribonuclease P/MRP family, (S. cerevisiae)
chrX_-_155216444 1.110 ENSMUST00000026318.8
Sat1
spermidine/spermine N1-acetyl transferase 1
chr5_-_137786651 1.089 ENSMUST00000031740.9
Mepce
methylphosphate capping enzyme
chr8_+_122775497 1.088 ENSMUST00000015160.5
Acsf3
acyl-CoA synthetase family member 3
chr11_-_40733373 1.088 ENSMUST00000020579.8
Hmmr
hyaluronan mediated motility receptor (RHAMM)
chr8_+_45885479 1.086 ENSMUST00000034053.5
Pdlim3
PDZ and LIM domain 3
chr7_-_19629355 1.053 ENSMUST00000049912.8
ENSMUST00000094762.3
ENSMUST00000098754.4
Relb


avian reticuloendotheliosis viral (v-rel) oncogene related B


chr6_+_15196949 1.047 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
Foxp2



forkhead box P2



chr11_-_87108656 1.046 ENSMUST00000051395.8
Prr11
proline rich 11
chr8_+_92674826 1.040 ENSMUST00000167261.2
Irx6
Iroquois related homeobox 6 (Drosophila)
chr3_+_89459118 1.030 ENSMUST00000029564.5
Pmvk
phosphomevalonate kinase
chr1_-_191575534 1.027 ENSMUST00000027933.5
Dtl
denticleless homolog (Drosophila)
chr15_+_79347534 1.027 ENSMUST00000096350.3
Maff
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr16_+_21794320 1.019 ENSMUST00000181780.1
ENSMUST00000181960.1
1300002E11Rik

RIKEN cDNA 1300002E11 gene

chr4_+_3938888 1.018 ENSMUST00000121110.1
ENSMUST00000108386.1
ENSMUST00000149544.1
Chchd7


coiled-coil-helix-coiled-coil-helix domain containing 7


chr2_-_150668198 1.018 ENSMUST00000028944.3
Acss1
acyl-CoA synthetase short-chain family member 1
chrX_+_106187100 1.017 ENSMUST00000081593.6
Pgk1
phosphoglycerate kinase 1
chr12_+_84316830 1.013 ENSMUST00000045931.10
Zfp410
zinc finger protein 410
chr10_-_30200492 1.008 ENSMUST00000099985.4
Cenpw
centromere protein W
chr5_-_110653348 1.002 ENSMUST00000042147.5
Noc4l
nucleolar complex associated 4 homolog (S. cerevisiae)
chr2_-_23155864 1.001 ENSMUST00000028119.6
Mastl
microtubule associated serine/threonine kinase-like
chr5_-_137786681 0.999 ENSMUST00000132726.1
Mepce
methylphosphate capping enzyme
chr4_+_115737738 0.987 ENSMUST00000106525.2
Efcab14
EF-hand calcium binding domain 14
chr11_-_69980468 0.979 ENSMUST00000143175.1
Elp5
elongator acetyltransferase complex subunit 5
chr16_+_38562821 0.969 ENSMUST00000163948.1
Tmem39a
transmembrane protein 39a
chr4_-_131838231 0.965 ENSMUST00000030741.2
ENSMUST00000105987.2
Ptpru

protein tyrosine phosphatase, receptor type, U

chr6_-_25809189 0.955 ENSMUST00000115327.1
Pot1a
protection of telomeres 1A
chr17_+_34982099 0.954 ENSMUST00000007266.7
Lsm2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr17_+_34982154 0.943 ENSMUST00000173004.1
Lsm2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr14_-_55745647 0.936 ENSMUST00000002403.8
Dhrs1
dehydrogenase/reductase (SDR family) member 1
chr2_-_127788854 0.916 ENSMUST00000028857.7
ENSMUST00000110357.1
Nphp1

nephronophthisis 1 (juvenile) homolog (human)

chr5_+_9100681 0.913 ENSMUST00000115365.1
Tmem243
transmembrane protein 243, mitochondrial
chr13_-_22042949 0.912 ENSMUST00000091741.4
Hist1h2ag
histone cluster 1, H2ag
chr7_-_34655500 0.912 ENSMUST00000032709.1
Kctd15
potassium channel tetramerisation domain containing 15
chr7_+_45718121 0.909 ENSMUST00000135500.2
Rpl18
ribosomal protein L18
chr1_+_92831614 0.892 ENSMUST00000045970.6
Gpc1
glypican 1
chr13_-_29984219 0.887 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr7_-_45717890 0.886 ENSMUST00000107738.3
Sphk2
sphingosine kinase 2
chr16_-_4789887 0.883 ENSMUST00000117713.1
Cdip1
cell death inducing Trp53 target 1
chrX_-_8145713 0.879 ENSMUST00000115615.2
ENSMUST00000115616.1
ENSMUST00000115621.2
Rbm3


RNA binding motif protein 3


chr16_-_4789984 0.878 ENSMUST00000004173.5
Cdip1
cell death inducing Trp53 target 1
chr1_-_77515048 0.877 ENSMUST00000027451.6
Epha4
Eph receptor A4
chr16_+_20693263 0.858 ENSMUST00000149543.1
ENSMUST00000118919.1
Fam131a

family with sequence similarity 131, member A

chr7_-_30664986 0.851 ENSMUST00000019697.8
Haus5
HAUS augmin-like complex, subunit 5
chr6_-_25809210 0.837 ENSMUST00000115330.1
ENSMUST00000115329.1
Pot1a

protection of telomeres 1A

chr17_+_34981847 0.828 ENSMUST00000114011.4
Lsm2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr9_+_46012810 0.824 ENSMUST00000126865.1
Sik3
SIK family kinase 3
chr12_-_27342696 0.824 ENSMUST00000079063.5
Sox11
SRY-box containing gene 11
chr16_+_38562806 0.819 ENSMUST00000171687.1
ENSMUST00000002924.8
Tmem39a

transmembrane protein 39a

chr7_-_109781538 0.818 ENSMUST00000033331.6
Nrip3
nuclear receptor interacting protein 3
chr11_+_69965396 0.816 ENSMUST00000018713.6
Cldn7
claudin 7
chr9_+_74861888 0.811 ENSMUST00000056006.9
Onecut1
one cut domain, family member 1
chrX_+_74254782 0.810 ENSMUST00000119197.1
ENSMUST00000088313.4
Emd

emerin

chr2_+_162931520 0.804 ENSMUST00000130411.1
Srsf6
serine/arginine-rich splicing factor 6
chr4_-_132075250 0.792 ENSMUST00000105970.1
ENSMUST00000105975.1
Epb4.1

erythrocyte protein band 4.1

chr8_-_22653406 0.792 ENSMUST00000033938.5
Polb
polymerase (DNA directed), beta
chr10_+_121033960 0.784 ENSMUST00000020439.4
ENSMUST00000175867.1
Wif1

Wnt inhibitory factor 1

chr2_-_132253227 0.768 ENSMUST00000028817.6
Pcna
proliferating cell nuclear antigen
chr1_+_75168631 0.764 ENSMUST00000162768.1
ENSMUST00000160439.1
ENSMUST00000027394.5
Zfand2b


zinc finger, AN1 type domain 2B


chr17_+_84626458 0.764 ENSMUST00000025101.8
Dync2li1
dynein cytoplasmic 2 light intermediate chain 1
chr18_-_56562261 0.756 ENSMUST00000066208.6
ENSMUST00000172734.1
Aldh7a1

aldehyde dehydrogenase family 7, member A1

chr8_-_80739497 0.748 ENSMUST00000043359.8
Smarca5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr3_-_85741389 0.746 ENSMUST00000094148.4
Fam160a1
family with sequence similarity 160, member A1
chr12_+_52097737 0.745 ENSMUST00000040090.9
Nubpl
nucleotide binding protein-like
chr4_+_3938904 0.744 ENSMUST00000120732.1
ENSMUST00000041122.4
ENSMUST00000121651.1
ENSMUST00000121210.1
ENSMUST00000119307.1
ENSMUST00000123769.1
Chchd7





coiled-coil-helix-coiled-coil-helix domain containing 7





chr2_-_127444524 0.744 ENSMUST00000028848.3
Fahd2a
fumarylacetoacetate hydrolase domain containing 2A
chr7_-_45717919 0.733 ENSMUST00000107737.2
Sphk2
sphingosine kinase 2
chr8_-_84067283 0.718 ENSMUST00000071067.3
C330011M18Rik
RIKEN cDNA C330011M18 gene
chrX_-_8145679 0.713 ENSMUST00000115619.1
ENSMUST00000115617.3
ENSMUST00000040010.3
Rbm3


RNA binding motif protein 3


chr17_-_25844514 0.706 ENSMUST00000176709.1
Rhot2
ras homolog gene family, member T2

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.8 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
2.2 8.7 GO:1902724 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
2.2 10.8 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
1.3 15.7 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
1.3 3.8 GO:0051316 attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316)
1.2 4.9 GO:0045903 positive regulation of translational fidelity(GO:0045903)
1.2 12.7 GO:0030432 peristalsis(GO:0030432)
1.1 3.3 GO:2000373 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
1.1 5.4 GO:1904672 regulation of somatic stem cell population maintenance(GO:1904672)
1.1 6.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
1.0 3.1 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
1.0 2.9 GO:1901079 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) positive regulation of relaxation of muscle(GO:1901079)
1.0 5.9 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.9 6.2 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.9 2.6 GO:0072284 cervix development(GO:0060067) metanephric S-shaped body morphogenesis(GO:0072284) anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.8 3.4 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.7 2.2 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.7 4.9 GO:0098535 positive regulation of centriole replication(GO:0046601) de novo centriole assembly(GO:0098535)
0.7 5.9 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.6 1.9 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.6 1.8 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.5 4.9 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.5 1.6 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.5 2.1 GO:0060578 extraocular skeletal muscle development(GO:0002074) subthalamic nucleus development(GO:0021763) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.5 5.8 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.5 4.7 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.5 7.6 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.5 2.0 GO:0090467 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.5 1.8 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.5 2.7 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.4 0.9 GO:0070344 fat cell proliferation(GO:0070341) regulation of fat cell proliferation(GO:0070344) negative regulation of fat cell proliferation(GO:0070345)
0.4 2.7 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.4 1.3 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.4 1.3 GO:0035973 aggrephagy(GO:0035973)
0.4 1.1 GO:0014028 notochord formation(GO:0014028) axial mesoderm morphogenesis(GO:0048319)
0.4 0.4 GO:1903722 regulation of centriole elongation(GO:1903722)
0.4 2.5 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.4 1.1 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.4 1.8 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.3 1.0 GO:0006083 acetate metabolic process(GO:0006083)
0.3 1.3 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.3 3.6 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.3 3.8 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.3 1.6 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.3 0.9 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.3 1.5 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.3 1.2 GO:0032202 negative regulation of protein ADP-ribosylation(GO:0010836) telomere assembly(GO:0032202)
0.3 0.9 GO:2001016 heparan sulfate proteoglycan catabolic process(GO:0030200) positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.3 0.9 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.3 2.9 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.3 0.8 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.3 2.1 GO:0040031 snRNA modification(GO:0040031)
0.2 3.9 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.2 4.6 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.2 6.7 GO:0034508 centromere complex assembly(GO:0034508)
0.2 2.7 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.2 2.3 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.2 3.6 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.2 0.7 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.2 1.3 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.2 1.5 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.2 1.4 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.2 1.4 GO:0072697 protein localization to cell cortex(GO:0072697)
0.2 0.8 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.2 0.6 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.2 6.8 GO:0016572 histone phosphorylation(GO:0016572)
0.2 7.0 GO:0001709 cell fate determination(GO:0001709)
0.2 0.8 GO:1902990 leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.2 3.3 GO:0072520 seminiferous tubule development(GO:0072520)
0.2 2.1 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.2 0.9 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.2 0.7 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.2 0.5 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.2 3.4 GO:0007530 sex determination(GO:0007530)
0.2 0.3 GO:1905154 negative regulation of membrane invagination(GO:1905154)
0.2 0.5 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.2 0.6 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.6 GO:0051309 female meiosis chromosome separation(GO:0051309)
0.1 0.8 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.7 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 2.4 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 1.3 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 0.4 GO:0016237 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521) negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis(GO:0090157)
0.1 0.8 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1 1.9 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.1 0.5 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780)
0.1 0.4 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.1 4.5 GO:0009409 response to cold(GO:0009409)
0.1 0.6 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 0.5 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1 1.0 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 1.8 GO:0042407 cristae formation(GO:0042407)
0.1 0.7 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 1.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 1.3 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.8 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 0.3 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.1 0.4 GO:0060017 parathyroid gland development(GO:0060017)
0.1 0.6 GO:0070365 hepatocyte differentiation(GO:0070365)
0.1 0.3 GO:2000850 negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.1 0.4 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 1.1 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 1.1 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 1.1 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.1 1.8 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 0.2 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.1 1.0 GO:0019985 translesion synthesis(GO:0019985)
0.1 3.1 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 0.6 GO:0016584 nucleosome positioning(GO:0016584)
0.1 1.2 GO:0060693 regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.1 1.0 GO:0031639 plasminogen activation(GO:0031639)
0.1 0.4 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 1.6 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.1 0.4 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.9 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.1 2.3 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.1 0.8 GO:1990403 embryonic brain development(GO:1990403)
0.1 1.1 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.1 1.1 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.1 0.3 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 0.2 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.1 0.6 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 1.3 GO:0044458 motile cilium assembly(GO:0044458)
0.1 1.1 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 0.3 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.2 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 5.5 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.1 0.6 GO:0006824 cobalt ion transport(GO:0006824)
0.1 2.2 GO:0035082 axoneme assembly(GO:0035082)
0.1 0.4 GO:0032790 ribosome disassembly(GO:0032790)
0.1 4.3 GO:0071774 response to fibroblast growth factor(GO:0071774)
0.1 0.8 GO:0032460 negative regulation of protein oligomerization(GO:0032460) negative regulation of protein homooligomerization(GO:0032463)
0.1 0.6 GO:0010225 response to UV-C(GO:0010225)
0.1 0.5 GO:0030049 muscle filament sliding(GO:0030049)
0.1 0.4 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.1 GO:0021593 rhombomere morphogenesis(GO:0021593)
0.0 5.2 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.3 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.5 GO:0051923 sulfation(GO:0051923)
0.0 1.4 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 2.9 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.4 GO:0061525 hindgut development(GO:0061525)
0.0 0.6 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.0 2.2 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 1.3 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.7 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 1.1 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.8 GO:0051654 establishment of mitochondrion localization(GO:0051654)
0.0 0.4 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.2 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.4 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 1.1 GO:0048536 spleen development(GO:0048536)
0.0 0.1 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.0 0.2 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
0.0 0.8 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.2 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.2 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.9 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.8 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.3 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.4 GO:0000012 single strand break repair(GO:0000012)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 1.1 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.4 GO:0034204 lipid translocation(GO:0034204)
0.0 0.4 GO:0030813 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.0 0.8 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.4 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.5 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.7 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.0 0.1 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.3 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.1 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0031442 positive regulation of mRNA 3'-end processing(GO:0031442)
0.0 0.2 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.4 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.7 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.8 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.0 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0 0.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.4 GO:0042633 molting cycle(GO:0042303) hair cycle(GO:0042633)
0.0 0.4 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.3 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.3 GO:0035329 hippo signaling(GO:0035329)
0.0 0.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.4 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.6 GO:0071148 TEAD-1-YAP complex(GO:0071148)
1.4 5.5 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
1.1 3.3 GO:0000799 nuclear condensin complex(GO:0000799)
1.1 10.6 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
1.0 3.1 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
1.0 7.2 GO:0001940 male pronucleus(GO:0001940)
0.8 4.9 GO:0098536 deuterosome(GO:0098536)
0.8 6.8 GO:0000813 ESCRT I complex(GO:0000813)
0.6 2.9 GO:0042583 chromaffin granule(GO:0042583)
0.5 3.1 GO:0070531 BRCA1-A complex(GO:0070531)
0.5 3.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.5 2.4 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.4 2.2 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.4 1.3 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.4 3.0 GO:0070187 telosome(GO:0070187)
0.4 2.7 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.4 6.0 GO:0030008 TRAPP complex(GO:0030008)
0.4 5.9 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.3 2.2 GO:0001520 outer dense fiber(GO:0001520)
0.3 0.8 GO:0070557 PCNA-p21 complex(GO:0070557)
0.2 1.0 GO:0030689 Noc complex(GO:0030689)
0.2 1.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 9.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 1.8 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.2 7.0 GO:0097546 ciliary base(GO:0097546)
0.2 2.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.2 1.4 GO:0061617 MICOS complex(GO:0061617)
0.2 4.7 GO:0051233 spindle midzone(GO:0051233)
0.2 1.1 GO:0033503 HULC complex(GO:0033503)
0.2 2.1 GO:0016589 NURF complex(GO:0016589)
0.2 1.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 1.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 4.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.6 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.9 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 1.0 GO:0070652 HAUS complex(GO:0070652)
0.1 1.5 GO:0032156 septin cytoskeleton(GO:0032156)
0.1 4.2 GO:0000786 nucleosome(GO:0000786)
0.1 1.4 GO:0071437 invadopodium(GO:0071437)
0.1 7.7 GO:0005844 polysome(GO:0005844)
0.1 1.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.4 GO:0005745 m-AAA complex(GO:0005745)
0.1 0.6 GO:0000125 PCAF complex(GO:0000125)
0.1 1.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 3.4 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.4 GO:0097447 dendritic tree(GO:0097447)
0.1 0.5 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) Holliday junction resolvase complex(GO:0048476)
0.1 0.6 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.6 GO:0000796 condensin complex(GO:0000796)
0.1 0.8 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.6 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 2.3 GO:0005876 spindle microtubule(GO:0005876)
0.1 0.3 GO:0042827 platelet dense granule(GO:0042827)
0.1 0.4 GO:1990246 uniplex complex(GO:1990246)
0.1 11.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 4.0 GO:0016459 myosin complex(GO:0016459)
0.1 1.6 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 1.5 GO:0071011 precatalytic spliceosome(GO:0071011)
0.1 2.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 14.0 GO:0005667 transcription factor complex(GO:0005667)
0.1 3.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 6.3 GO:0000776 kinetochore(GO:0000776)
0.1 0.5 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 0.7 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.5 GO:0001739 sex chromatin(GO:0001739)
0.0 0.3 GO:0034709 methylosome(GO:0034709)
0.0 0.6 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.4 GO:0089701 U2AF(GO:0089701)
0.0 0.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 3.3 GO:0000793 condensed chromosome(GO:0000793)
0.0 0.3 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.3 GO:0032009 early phagosome(GO:0032009)
0.0 4.1 GO:0015934 large ribosomal subunit(GO:0015934)
0.0 1.1 GO:0030286 dynein complex(GO:0030286)
0.0 0.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 1.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.5 GO:0097225 sperm midpiece(GO:0097225)
0.0 1.1 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 2.1 GO:0016605 PML body(GO:0016605)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.9 GO:0030673 axolemma(GO:0030673)
0.0 0.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.0 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.3 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.0 GO:0036126 sperm flagellum(GO:0036126)
0.0 4.0 GO:0005769 early endosome(GO:0005769)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.4 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0005840 ribosome(GO:0005840)
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 1.9 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.4 GO:0034702 ion channel complex(GO:0034702)
0.0 0.2 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 2.4 GO:0000790 nuclear chromatin(GO:0000790)
0.0 2.2 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 12.7 GO:0004994 somatostatin receptor activity(GO:0004994)
1.4 6.8 GO:0043515 kinetochore binding(GO:0043515)
0.9 7.7 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.8 4.9 GO:1990932 5.8S rRNA binding(GO:1990932)
0.8 2.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.7 2.2 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.7 10.8 GO:0003680 AT DNA binding(GO:0003680)
0.6 1.8 GO:1990955 G-rich single-stranded DNA binding(GO:1990955)
0.5 2.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.5 2.4 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.5 2.8 GO:0042731 PH domain binding(GO:0042731)
0.5 2.8 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.4 1.8 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.4 1.3 GO:0019776 Atg8 ligase activity(GO:0019776)
0.4 6.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.4 2.1 GO:0032027 myosin light chain binding(GO:0032027)
0.4 1.6 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.4 5.9 GO:0001054 RNA polymerase I activity(GO:0001054)
0.4 3.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.4 1.1 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.3 1.0 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.3 2.0 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.3 1.3 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.3 7.7 GO:0008266 poly(U) RNA binding(GO:0008266)
0.3 3.6 GO:0031996 thioesterase binding(GO:0031996)
0.3 0.9 GO:0070052 collagen V binding(GO:0070052)
0.3 5.2 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.3 0.8 GO:0032139 DNA polymerase processivity factor activity(GO:0030337) dinucleotide insertion or deletion binding(GO:0032139)
0.3 1.0 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.3 1.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 1.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 6.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 0.6 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.2 0.6 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.2 0.6 GO:0071633 dihydroceramidase activity(GO:0071633)
0.2 8.6 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.2 1.6 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 0.7 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.2 0.8 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.9 GO:0070180 ligase inhibitor activity(GO:0055104) large ribosomal subunit rRNA binding(GO:0070180) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 0.4 GO:0043426 MRF binding(GO:0043426)
0.1 5.4 GO:0005109 frizzled binding(GO:0005109)
0.1 0.4 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.1 0.4 GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699)
0.1 2.7 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 0.6 GO:0071837 HMG box domain binding(GO:0071837)
0.1 1.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 1.5 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 2.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 1.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 0.9 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.8 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 0.6 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 1.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 4.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.3 GO:0030519 snoRNP binding(GO:0030519)
0.1 0.3 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 2.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.3 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 2.9 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 1.1 GO:0001618 virus receptor activity(GO:0001618)
0.1 0.4 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 0.5 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 15.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 0.5 GO:0000150 recombinase activity(GO:0000150)
0.1 3.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 1.5 GO:0004707 MAP kinase activity(GO:0004707)
0.1 3.7 GO:0003684 damaged DNA binding(GO:0003684)
0.1 1.1 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 1.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 0.4 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 1.2 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 0.5 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 3.4 GO:0004497 monooxygenase activity(GO:0004497)
0.1 3.5 GO:0030507 spectrin binding(GO:0030507)
0.1 1.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.8 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 1.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.1 GO:0005521 lamin binding(GO:0005521)
0.1 0.4 GO:0050733 RS domain binding(GO:0050733)
0.1 0.2 GO:0004458 D-lactate dehydrogenase (cytochrome) activity(GO:0004458) oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor(GO:0016898)
0.1 0.3 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.8 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.6 GO:0043495 protein anchor(GO:0043495)
0.0 1.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 4.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.8 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 2.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.8 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.0 2.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 1.1 GO:0016878 acid-thiol ligase activity(GO:0016878)
0.0 0.4 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 4.4 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 2.5 GO:0031491 nucleosome binding(GO:0031491)
0.0 3.0 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 1.0 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 2.0 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.4 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.8 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 5.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.5 GO:0020037 heme binding(GO:0020037)
0.0 0.7 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 1.7 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0 0.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 13.0 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.8 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.8 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 1.3 GO:0016879 ligase activity, forming carbon-nitrogen bonds(GO:0016879)
0.0 0.0 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.0 0.3 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.8 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 3.4 GO:0042393 histone binding(GO:0042393)
0.0 0.1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 2.1 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)
0.0 0.2 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.4 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.4 GO:0001784 phosphotyrosine binding(GO:0001784)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 9.7 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.5 9.7 ST_STAT3_PATHWAY STAT3 Pathway
0.3 11.5 PID_BARD1_PATHWAY BARD1 signaling events
0.3 12.1 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 2.6 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 2.3 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 4.7 PID_PLK1_PATHWAY PLK1 signaling events
0.1 1.1 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.1 3.1 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.1 3.5 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 5.6 PID_CDC42_PATHWAY CDC42 signaling events
0.1 7.9 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.1 0.4 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 3.2 PID_E2F_PATHWAY E2F transcription factor network
0.0 0.3 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 0.9 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 0.6 PID_MYC_PATHWAY C-MYC pathway
0.0 2.1 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.8 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 2.3 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 0.5 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 1.4 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.2 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 0.6 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.3 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.4 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.9 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.1 PID_FOXO_PATHWAY FoxO family signaling
0.0 0.4 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.0 0.4 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.6 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 0.3 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 6.2 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.8 10.8 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.7 8.7 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.6 6.8 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.4 7.2 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.3 8.8 REACTOME_KINESINS Genes involved in Kinesins
0.3 1.0 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.2 1.2 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.2 3.1 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.2 11.4 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.2 9.8 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2 5.6 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 2.7 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 2.2 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 3.4 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 9.4 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 1.1 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 0.9 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 1.3 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 2.4 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 7.6 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 1.6 REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_MULTIPLE_NUCLEOTIDE_PATCH_REPLACEMENT_PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.1 2.3 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 4.7 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 2.2 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 5.4 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 3.5 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.1 2.0 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.1 1.4 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 0.3 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 2.2 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 2.0 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.7 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.3 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.6 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 1.3 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.6 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.8 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.8 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.0 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 1.5 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.4 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.0 0.4 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 1.6 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 0.5 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.5 REACTOME_MUSCLE_CONTRACTION Genes involved in Muscle contraction
0.0 0.4 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.4 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.4 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.4 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.7 REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.4 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.3 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription