Motif ID: Bbx

Z-value: 0.282


Transcription factors associated with Bbx:

Gene SymbolEntrez IDGene Name
Bbx ENSMUSG00000022641.9 Bbx

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bbxmm10_v2_chr16_-_50432340_50432409-0.409.7e-03Click!


Activity profile for motif Bbx.

activity profile for motif Bbx


Sorted Z-values histogram for motif Bbx

Sorted Z-values for motif Bbx



Network of associatons between targets according to the STRING database.



First level regulatory network of Bbx

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_+_21111452 3.201 ENSMUST00000075132.6
Cdh12
cadherin 12
chr13_-_52530827 2.890 ENSMUST00000057442.6
Diras2
DIRAS family, GTP-binding RAS-like 2
chr5_-_146585239 1.634 ENSMUST00000036211.6
Gpr12
G-protein coupled receptor 12
chr18_+_37421418 1.631 ENSMUST00000053073.4
Pcdhb11
protocadherin beta 11
chr17_+_57358682 1.141 ENSMUST00000086763.5
ENSMUST00000004850.7
Emr1

EGF-like module containing, mucin-like, hormone receptor-like sequence 1

chr10_+_86021961 1.139 ENSMUST00000130320.1
Fbxo7
F-box protein 7
chr8_+_70616816 0.724 ENSMUST00000052437.3
Lrrc25
leucine rich repeat containing 25
chrX_+_140367494 0.710 ENSMUST00000141660.1
Frmpd3
FERM and PDZ domain containing 3
chr2_+_136892168 0.507 ENSMUST00000099311.2
Slx4ip
SLX4 interacting protein
chr7_-_127708738 0.346 ENSMUST00000106282.1
Bcl7c
B cell CLL/lymphoma 7C
chrX_+_159708593 0.344 ENSMUST00000080394.6
Sh3kbp1
SH3-domain kinase binding protein 1
chr6_+_124304646 0.297 ENSMUST00000112541.2
ENSMUST00000032234.2
Cd163

CD163 antigen

chrX_-_107816238 0.254 ENSMUST00000120722.1
2610002M06Rik
RIKEN cDNA 2610002M06 gene
chr13_+_49608030 0.246 ENSMUST00000021822.5
Ogn
osteoglycin
chr1_-_13660476 0.241 ENSMUST00000027071.5
Lactb2
lactamase, beta 2
chr1_+_180111339 0.163 ENSMUST00000145181.1
Cdc42bpa
CDC42 binding protein kinase alpha
chr11_+_105146893 0.134 ENSMUST00000100338.1
Gm10842
predicted gene 10842
chr14_+_48670147 0.088 ENSMUST00000183522.1
ENSMUST00000184869.1
RP23-131O4.2

RP23-131O4.2

chrX_-_150814265 0.088 ENSMUST00000026302.6
ENSMUST00000129768.1
ENSMUST00000112699.2
Maged2


melanoma antigen, family D, 2


chr10_+_84622365 0.045 ENSMUST00000077175.5
Polr3b
polymerase (RNA) III (DNA directed) polypeptide B
chr17_+_40811089 0.035 ENSMUST00000024721.7
Rhag
Rhesus blood group-associated A glycoprotein
chr10_-_86022325 0.020 ENSMUST00000181665.1
A230060F14Rik
RIKEN cDNA A230060F14 gene
chr7_-_127708886 0.009 ENSMUST00000061468.8
Bcl7c
B cell CLL/lymphoma 7C

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:1903207 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.0 3.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.3 GO:0006953 acute-phase response(GO:0006953)
0.0 0.1 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.0 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 0.2 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:1990037 Lewy body core(GO:1990037)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.3 GO:0005044 scavenger receptor activity(GO:0005044)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.9 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)