Motif ID: Cdc5l
Z-value: 0.770
Transcription factors associated with Cdc5l:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Cdc5l | ENSMUSG00000023932.8 | Cdc5l |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Cdc5l | mm10_v2_chr17_-_45433682_45433709 | 0.40 | 1.1e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 2.8 | GO:1903538 | meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538) |
| 0.7 | 5.5 | GO:2000301 | negative regulation of synaptic vesicle exocytosis(GO:2000301) |
| 0.4 | 3.3 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.2 | 2.0 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
| 0.2 | 10.1 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.2 | 2.5 | GO:0045187 | regulation of circadian sleep/wake cycle, sleep(GO:0045187) |
| 0.1 | 2.1 | GO:0042759 | long-chain fatty acid biosynthetic process(GO:0042759) |
| 0.1 | 0.9 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
| 0.1 | 0.6 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 0.1 | 0.3 | GO:0060126 | hypophysis morphogenesis(GO:0048850) somatotropin secreting cell differentiation(GO:0060126) |
| 0.1 | 2.9 | GO:0048665 | neuron fate specification(GO:0048665) |
| 0.0 | 2.0 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184) |
| 0.0 | 1.1 | GO:0007097 | nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023) |
| 0.0 | 1.8 | GO:0008333 | endosome to lysosome transport(GO:0008333) |
| 0.0 | 7.3 | GO:0031032 | actomyosin structure organization(GO:0031032) |
| 0.0 | 0.3 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.0 | 0.4 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.0 | 2.8 | GO:0007219 | Notch signaling pathway(GO:0007219) |
| 0.0 | 0.2 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 5.5 | GO:0097449 | astrocyte projection(GO:0097449) |
| 0.3 | 1.8 | GO:0070695 | FHF complex(GO:0070695) |
| 0.1 | 2.0 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.1 | 2.0 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.1 | 0.9 | GO:0043196 | varicosity(GO:0043196) |
| 0.1 | 1.1 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 1.3 | GO:0072562 | blood microparticle(GO:0072562) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 5.5 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 0.8 | 3.3 | GO:0047275 | glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275) |
| 0.3 | 2.1 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.2 | 2.9 | GO:0050897 | cobalt ion binding(GO:0050897) |
| 0.1 | 2.5 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.1 | 0.3 | GO:0000832 | inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
| 0.1 | 2.8 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.1 | 0.9 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.1 | 1.8 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 0.1 | 1.1 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.1 | 1.3 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.0 | 10.1 | GO:0005516 | calmodulin binding(GO:0005516) |
| 0.0 | 0.3 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.0 | 7.3 | GO:0003779 | actin binding(GO:0003779) |
| 0.0 | 2.0 | GO:0004386 | helicase activity(GO:0004386) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.8 | PID_ANGIOPOIETIN_RECEPTOR_PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.0 | 1.1 | PID_ER_NONGENOMIC_PATHWAY | Plasma membrane estrogen receptor signaling |
| 0.0 | 2.0 | PID_AR_TF_PATHWAY | Regulation of Androgen receptor activity |
| 0.0 | 1.1 | PID_CDC42_PATHWAY | CDC42 signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.8 | REACTOME_TIE2_SIGNALING | Genes involved in Tie2 Signaling |
| 0.0 | 2.0 | REACTOME_MRNA_3_END_PROCESSING | Genes involved in mRNA 3'-end processing |
| 0.0 | 0.9 | REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.0 | 0.7 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
