Motif ID: Crem_Jdp2

Z-value: 0.508

Transcription factors associated with Crem_Jdp2:

Gene SymbolEntrez IDGene Name
Crem ENSMUSG00000063889.10 Crem
Jdp2 ENSMUSG00000034271.9 Jdp2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Jdp2mm10_v2_chr12_+_85599388_85599416-0.472.1e-03Click!
Cremmm10_v2_chr18_-_3337539_33376000.343.1e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Crem_Jdp2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_23248264 8.113 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr11_+_101468164 4.583 ENSMUST00000001347.6
Rnd2
Rho family GTPase 2
chr3_+_135212557 3.783 ENSMUST00000062893.7
Cenpe
centromere protein E
chr1_-_134079114 3.230 ENSMUST00000020692.6
Btg2
B cell translocation gene 2, anti-proliferative
chr17_+_43952999 3.036 ENSMUST00000177857.1
Rcan2
regulator of calcineurin 2
chr17_+_43953191 2.880 ENSMUST00000044792.4
Rcan2
regulator of calcineurin 2
chr7_+_79500081 2.633 ENSMUST00000181511.2
ENSMUST00000182937.1
AI854517

expressed sequence AI854517

chr15_+_34238026 2.625 ENSMUST00000022867.3
Laptm4b
lysosomal-associated protein transmembrane 4B
chr7_+_79500018 2.426 ENSMUST00000182495.1
ENSMUST00000183043.1
AI854517

expressed sequence AI854517

chr1_+_74791516 2.209 ENSMUST00000006718.8
Wnt10a
wingless related MMTV integration site 10a
chr5_-_106458440 2.127 ENSMUST00000086795.6
Barhl2
BarH-like 2 (Drosophila)
chr11_-_84525514 1.983 ENSMUST00000018842.7
Lhx1
LIM homeobox protein 1
chr4_+_8690399 1.915 ENSMUST00000127476.1
Chd7
chromodomain helicase DNA binding protein 7
chr1_+_184034381 1.870 ENSMUST00000048655.7
Dusp10
dual specificity phosphatase 10
chr1_+_135729147 1.831 ENSMUST00000027677.7
Csrp1
cysteine and glycine-rich protein 1
chr3_+_125404072 1.788 ENSMUST00000173932.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr6_+_113531675 1.757 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2

Fanconi anemia, complementation group D2

chr7_-_142899985 1.746 ENSMUST00000000219.3
Th
tyrosine hydroxylase
chr3_+_31095052 1.718 ENSMUST00000118470.1
ENSMUST00000029194.5
ENSMUST00000123532.1
ENSMUST00000117728.1
Skil



SKI-like



chr2_+_109280738 1.589 ENSMUST00000028527.7
Kif18a
kinesin family member 18A
chr3_+_125404292 1.553 ENSMUST00000144344.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr11_+_113619318 1.523 ENSMUST00000146390.2
ENSMUST00000106630.1
Sstr2

somatostatin receptor 2

chr11_-_88718223 1.503 ENSMUST00000107909.1
Msi2
musashi RNA-binding protein 2
chr2_+_105668888 1.475 ENSMUST00000111086.4
ENSMUST00000111087.3
Pax6

paired box gene 6

chr11_+_64435315 1.387 ENSMUST00000058652.5
Hs3st3a1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr14_+_47472547 1.375 ENSMUST00000168833.1
ENSMUST00000163324.1
ENSMUST00000043112.7
Fbxo34


F-box protein 34


chr7_-_137314394 1.369 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
Ebf3



early B cell factor 3



chr7_+_112679327 1.367 ENSMUST00000106638.2
Tead1
TEA domain family member 1
chr5_-_69341699 1.352 ENSMUST00000054095.4
Kctd8
potassium channel tetramerisation domain containing 8
chr14_+_47472628 1.350 ENSMUST00000095941.2
Fbxo34
F-box protein 34
chr9_-_20976762 1.333 ENSMUST00000054197.5
S1pr2
sphingosine-1-phosphate receptor 2
chr13_+_113035111 1.324 ENSMUST00000180543.1
ENSMUST00000181568.1
ENSMUST00000109244.2
ENSMUST00000181117.1
ENSMUST00000181741.1
Cdc20b




cell division cycle 20B




chr6_+_14901344 1.321 ENSMUST00000115477.1
Foxp2
forkhead box P2
chr11_-_78165521 1.281 ENSMUST00000017530.3
Traf4
TNF receptor associated factor 4
chr13_+_15463202 1.164 ENSMUST00000130065.1
Gli3
GLI-Kruppel family member GLI3
chr3_-_36571952 1.154 ENSMUST00000029270.3
Ccna2
cyclin A2
chr7_-_144939823 1.152 ENSMUST00000093962.4
Ccnd1
cyclin D1
chr7_+_112679314 1.144 ENSMUST00000084705.5
ENSMUST00000059768.10
Tead1

TEA domain family member 1

chr4_-_123750236 1.126 ENSMUST00000102636.3
Akirin1
akirin 1
chr15_+_25758755 1.124 ENSMUST00000131834.1
ENSMUST00000124966.1
Myo10

myosin X

chr11_+_84525669 1.109 ENSMUST00000126072.1
ENSMUST00000128121.1
1500016L03Rik

RIKEN cDNA 1500016L03 gene

chr1_+_107511489 1.107 ENSMUST00000064916.2
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr4_+_11704439 1.101 ENSMUST00000108304.2
Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chr11_+_84525647 1.095 ENSMUST00000134800.1
1500016L03Rik
RIKEN cDNA 1500016L03 gene
chr3_+_145118564 1.059 ENSMUST00000098538.2
ENSMUST00000106192.2
ENSMUST00000029920.8
ENSMUST00000098539.2
Odf2l



outer dense fiber of sperm tails 2-like



chr1_+_107511416 1.053 ENSMUST00000009356.4
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr8_-_24438937 1.049 ENSMUST00000052622.4
1810011O10Rik
RIKEN cDNA 1810011O10 gene
chrX_-_56598069 1.031 ENSMUST00000059899.2
Mmgt1
membrane magnesium transporter 1
chr2_+_105668935 1.022 ENSMUST00000142772.1
Pax6
paired box gene 6
chr11_-_100939357 1.014 ENSMUST00000092671.5
ENSMUST00000103114.1
Stat3

signal transducer and activator of transcription 3

chrX_-_7188713 1.013 ENSMUST00000004428.7
Clcn5
chloride channel 5
chr11_+_69324069 0.992 ENSMUST00000060956.6
ENSMUST00000108662.1
Trappc1

trafficking protein particle complex 1

chr6_+_15196949 0.987 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
Foxp2



forkhead box P2



chr11_-_100939540 0.982 ENSMUST00000127638.1
Stat3
signal transducer and activator of transcription 3
chr3_-_65958236 0.980 ENSMUST00000029416.7
Ccnl1
cyclin L1
chr11_+_69324055 0.977 ENSMUST00000102601.3
Trappc1
trafficking protein particle complex 1
chr11_-_100939457 0.969 ENSMUST00000138438.1
Stat3
signal transducer and activator of transcription 3
chr17_+_72918298 0.946 ENSMUST00000024857.6
Lbh
limb-bud and heart
chr9_-_96478596 0.934 ENSMUST00000071301.4
Rnf7
ring finger protein 7
chr12_+_52097737 0.929 ENSMUST00000040090.9
Nubpl
nucleotide binding protein-like
chr6_-_86669136 0.877 ENSMUST00000001184.7
Mxd1
MAX dimerization protein 1
chr17_-_26508463 0.871 ENSMUST00000025025.6
Dusp1
dual specificity phosphatase 1
chr1_-_79440039 0.860 ENSMUST00000049972.4
Scg2
secretogranin II
chr9_-_64172879 0.857 ENSMUST00000176299.1
ENSMUST00000130127.1
ENSMUST00000176794.1
ENSMUST00000177045.1
Zwilch



zwilch kinetochore protein



chr3_+_67374116 0.846 ENSMUST00000061322.8
Mlf1
myeloid leukemia factor 1
chr14_+_54476100 0.845 ENSMUST00000164766.1
ENSMUST00000164697.1
Rem2

rad and gem related GTP binding protein 2

chr10_+_44268328 0.845 ENSMUST00000039286.4
Atg5
autophagy related 5
chr6_+_34598530 0.839 ENSMUST00000115027.1
ENSMUST00000115026.1
Cald1

caldesmon 1

chr9_-_96478660 0.829 ENSMUST00000057500.4
Rnf7
ring finger protein 7
chr12_+_79130777 0.795 ENSMUST00000021550.6
Arg2
arginase type II
chr11_+_69323963 0.792 ENSMUST00000102602.1
Trappc1
trafficking protein particle complex 1
chr19_+_37376359 0.786 ENSMUST00000012587.3
Kif11
kinesin family member 11
chr3_+_67374091 0.784 ENSMUST00000077916.5
Mlf1
myeloid leukemia factor 1
chr14_+_14012491 0.778 ENSMUST00000022257.2
Atxn7
ataxin 7
chr6_+_34598500 0.769 ENSMUST00000079391.3
ENSMUST00000142512.1
Cald1

caldesmon 1

chr7_+_139389072 0.755 ENSMUST00000106098.1
ENSMUST00000026550.7
Inpp5a

inositol polyphosphate-5-phosphatase A

chr10_-_92722356 0.750 ENSMUST00000020163.6
Nedd1
neural precursor cell expressed, developmentally down-regulated gene 1
chr13_-_64274879 0.745 ENSMUST00000109770.1
Cdc14b
CDC14 cell division cycle 14B
chr9_+_102718424 0.735 ENSMUST00000156485.1
ENSMUST00000145937.1
ENSMUST00000134483.1
Amotl2


angiomotin-like 2


chr5_-_124032214 0.734 ENSMUST00000040967.7
Vps37b
vacuolar protein sorting 37B (yeast)
chr17_-_31855782 0.729 ENSMUST00000024839.4
Sik1
salt inducible kinase 1
chr4_+_115737738 0.725 ENSMUST00000106525.2
Efcab14
EF-hand calcium binding domain 14
chr2_-_36136773 0.712 ENSMUST00000028251.3
Rbm18
RNA binding motif protein 18
chr11_-_69323768 0.700 ENSMUST00000092973.5
Cntrob
centrobin, centrosomal BRCA2 interacting protein
chr2_-_36136602 0.692 ENSMUST00000122456.1
Rbm18
RNA binding motif protein 18
chr1_+_63273261 0.689 ENSMUST00000114132.1
ENSMUST00000126932.1
Zdbf2

zinc finger, DBF-type containing 2

chr10_-_42583628 0.672 ENSMUST00000019938.4
Nr2e1
nuclear receptor subfamily 2, group E, member 1
chr11_-_88718165 0.672 ENSMUST00000107908.1
Msi2
musashi RNA-binding protein 2
chr16_+_38562821 0.672 ENSMUST00000163948.1
Tmem39a
transmembrane protein 39a
chr17_-_56476462 0.660 ENSMUST00000067538.5
Ptprs
protein tyrosine phosphatase, receptor type, S
chr7_-_30664986 0.648 ENSMUST00000019697.8
Haus5
HAUS augmin-like complex, subunit 5
chr16_+_38562806 0.647 ENSMUST00000171687.1
ENSMUST00000002924.8
Tmem39a

transmembrane protein 39a

chr8_+_72135247 0.641 ENSMUST00000003575.9
Tpm4
tropomyosin 4
chr5_+_142960343 0.631 ENSMUST00000031565.8
Fscn1
fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)
chr6_-_30304513 0.627 ENSMUST00000094543.2
ENSMUST00000102993.3
Ube2h

ubiquitin-conjugating enzyme E2H

chr2_-_3475027 0.616 ENSMUST00000027956.2
Suv39h2
suppressor of variegation 3-9 homolog 2 (Drosophila)
chr2_-_3474954 0.609 ENSMUST00000060618.6
Suv39h2
suppressor of variegation 3-9 homolog 2 (Drosophila)
chr5_+_24164963 0.606 ENSMUST00000049887.6
Nupl2
nucleoporin like 2
chr13_+_23531044 0.597 ENSMUST00000102972.3
Hist1h4h
histone cluster 1, H4h
chr4_-_131838231 0.590 ENSMUST00000030741.2
ENSMUST00000105987.2
Ptpru

protein tyrosine phosphatase, receptor type, U

chr10_-_128176568 0.589 ENSMUST00000092033.2
Rbms2
RNA binding motif, single stranded interacting protein 2
chr3_+_127553462 0.588 ENSMUST00000043108.4
4930422G04Rik
RIKEN cDNA 4930422G04 gene
chr11_+_69965396 0.586 ENSMUST00000018713.6
Cldn7
claudin 7
chr19_+_8850785 0.582 ENSMUST00000096257.2
Lrrn4cl
LRRN4 C-terminal like
chr10_+_96616998 0.579 ENSMUST00000038377.7
Btg1
B cell translocation gene 1, anti-proliferative
chr7_-_118584669 0.576 ENSMUST00000044195.4
Tmc7
transmembrane channel-like gene family 7
chr9_-_105395237 0.574 ENSMUST00000140851.1
Nek11
NIMA (never in mitosis gene a)-related expressed kinase 11
chr11_+_108682602 0.571 ENSMUST00000106718.3
ENSMUST00000106715.1
ENSMUST00000106724.3
Cep112


centrosomal protein 112


chr2_-_23155864 0.569 ENSMUST00000028119.6
Mastl
microtubule associated serine/threonine kinase-like
chr3_+_88214474 0.553 ENSMUST00000181356.1
ENSMUST00000181396.1
Gm3764

predicted gene 3764

chr7_-_118533298 0.552 ENSMUST00000098090.3
ENSMUST00000032887.3
Coq7

demethyl-Q 7

chr7_+_125707945 0.534 ENSMUST00000148701.1
D430042O09Rik
RIKEN cDNA D430042O09 gene
chr4_+_32238713 0.532 ENSMUST00000108180.2
Bach2
BTB and CNC homology 2
chr3_+_129199919 0.525 ENSMUST00000029657.9
ENSMUST00000106382.4
Pitx2

paired-like homeodomain transcription factor 2

chr14_+_56887795 0.520 ENSMUST00000022511.8
Zmym2
zinc finger, MYM-type 2
chr13_-_19395728 0.518 ENSMUST00000039694.7
Stard3nl
STARD3 N-terminal like
chr17_-_27907706 0.512 ENSMUST00000025057.4
Taf11
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr2_+_167777467 0.502 ENSMUST00000139927.1
ENSMUST00000127441.1
Gm14321

predicted gene 14321

chr7_+_139248477 0.501 ENSMUST00000093993.3
ENSMUST00000172136.1
Pwwp2b

PWWP domain containing 2B

chr5_-_51553896 0.485 ENSMUST00000132734.1
Ppargc1a
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr2_+_122738495 0.473 ENSMUST00000005954.8
Bloc1s6
biogenesis of organelles complex-1, subunit 6, pallidin
chr13_+_42052015 0.471 ENSMUST00000060148.5
Hivep1
human immunodeficiency virus type I enhancer binding protein 1
chr17_+_36958623 0.471 ENSMUST00000173814.1
Znrd1as
Znrd1 antisense
chr1_+_75479529 0.466 ENSMUST00000113575.2
ENSMUST00000148980.1
ENSMUST00000050899.6
Tmem198


transmembrane protein 198


chr2_+_30237680 0.465 ENSMUST00000113654.1
ENSMUST00000095078.2
Lrrc8a

leucine rich repeat containing 8A

chr10_+_80494835 0.454 ENSMUST00000051773.8
Onecut3
one cut domain, family member 3
chr12_-_27342696 0.449 ENSMUST00000079063.5
Sox11
SRY-box containing gene 11
chr10_-_128891674 0.449 ENSMUST00000026408.6
Gdf11
growth differentiation factor 11
chr8_-_110997764 0.448 ENSMUST00000040416.7
Ddx19a
DEAD (Asp-Glu-Ala-Asp) box polypeptide 19a
chr11_+_94044111 0.438 ENSMUST00000132079.1
Spag9
sperm associated antigen 9
chr10_-_128804353 0.434 ENSMUST00000051011.7
Tmem198b
transmembrane protein 198b
chr3_+_40800054 0.432 ENSMUST00000168287.1
Plk4
polo-like kinase 4
chr9_+_46012810 0.431 ENSMUST00000126865.1
Sik3
SIK family kinase 3
chr4_-_132075250 0.429 ENSMUST00000105970.1
ENSMUST00000105975.1
Epb4.1

erythrocyte protein band 4.1

chr13_-_54688065 0.424 ENSMUST00000125871.1
Rnf44
ring finger protein 44
chr5_-_97111565 0.424 ENSMUST00000112969.3
Paqr3
progestin and adipoQ receptor family member III
chr9_+_74861888 0.423 ENSMUST00000056006.9
Onecut1
one cut domain, family member 1
chr6_+_124808885 0.422 ENSMUST00000143040.1
ENSMUST00000052727.4
ENSMUST00000130160.1
Spsb2


splA/ryanodine receptor domain and SOCS box containing 2


chr7_+_63444741 0.421 ENSMUST00000058476.7
Otud7a
OTU domain containing 7A
chr2_+_19909769 0.416 ENSMUST00000114610.1
Etl4
enhancer trap locus 4
chr17_+_36958571 0.414 ENSMUST00000040177.6
Znrd1as
Znrd1 antisense
chr10_+_72654873 0.408 ENSMUST00000105431.1
ENSMUST00000160337.1
Zwint

ZW10 interactor

chrX_-_21061981 0.408 ENSMUST00000040628.5
ENSMUST00000115333.2
ENSMUST00000115334.1
Zfp182


zinc finger protein 182


chr2_+_156840077 0.404 ENSMUST00000081335.6
ENSMUST00000073352.3
Tgif2

TGFB-induced factor homeobox 2

chrX_-_111697069 0.402 ENSMUST00000113422.2
ENSMUST00000038472.5
Hdx

highly divergent homeobox

chr6_+_14901440 0.401 ENSMUST00000128567.1
Foxp2
forkhead box P2
chr8_+_22757744 0.400 ENSMUST00000033941.5
Plat
plasminogen activator, tissue
chr12_+_73286868 0.398 ENSMUST00000153941.1
ENSMUST00000122920.1
ENSMUST00000101313.3
Slc38a6


solute carrier family 38, member 6


chr9_+_46012822 0.397 ENSMUST00000120463.2
ENSMUST00000120247.1
Sik3

SIK family kinase 3

chr6_+_134035691 0.389 ENSMUST00000081028.6
ENSMUST00000111963.1
Etv6

ets variant gene 6 (TEL oncogene)

chr4_+_115737754 0.369 ENSMUST00000106522.2
Efcab14
EF-hand calcium binding domain 14
chr7_-_38271310 0.363 ENSMUST00000032585.6
Pop4
processing of precursor 4, ribonuclease P/MRP family, (S. cerevisiae)
chr13_-_64274962 0.351 ENSMUST00000039318.8
Cdc14b
CDC14 cell division cycle 14B
chr4_+_21931291 0.347 ENSMUST00000029908.7
Faxc
failed axon connections homolog (Drosophila)
chr17_+_84511832 0.343 ENSMUST00000047206.5
Plekhh2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr10_+_72654845 0.338 ENSMUST00000020081.4
Zwint
ZW10 interactor
chr5_-_5664196 0.330 ENSMUST00000061008.3
ENSMUST00000054865.6
A330021E22Rik

RIKEN cDNA A330021E22 gene

chr12_+_109540979 0.329 ENSMUST00000129245.1
ENSMUST00000143836.1
ENSMUST00000124106.1
Meg3


maternally expressed 3


chr13_-_54688264 0.328 ENSMUST00000150626.1
ENSMUST00000134177.1
Rnf44

ring finger protein 44

chr11_-_113751813 0.319 ENSMUST00000053536.4
Cdc42ep4
CDC42 effector protein (Rho GTPase binding) 4
chr4_+_43578709 0.318 ENSMUST00000107886.2
ENSMUST00000117140.1
Rgp1

RGP1 retrograde golgi transport homolog (S. cerevisiae)

chr13_-_54688246 0.313 ENSMUST00000122935.1
ENSMUST00000128257.1
Rnf44

ring finger protein 44

chr17_-_45573253 0.312 ENSMUST00000165127.1
ENSMUST00000166469.1
ENSMUST00000024739.7
Hsp90ab1


heat shock protein 90 alpha (cytosolic), class B member 1


chr4_-_56802265 0.312 ENSMUST00000030140.2
Ikbkap
inhibitor of kappa light polypeptide enhancer in B cells, kinase complex-associated protein
chr13_+_19623163 0.310 ENSMUST00000002883.5
Sfrp4
secreted frizzled-related protein 4
chr3_+_129199878 0.307 ENSMUST00000174661.2
Pitx2
paired-like homeodomain transcription factor 2
chr2_+_49619277 0.304 ENSMUST00000028102.7
Kif5c
kinesin family member 5C
chrX_-_8145713 0.301 ENSMUST00000115615.2
ENSMUST00000115616.1
ENSMUST00000115621.2
Rbm3


RNA binding motif protein 3


chr7_-_65370908 0.301 ENSMUST00000032729.6
Tjp1
tight junction protein 1
chr7_-_44748306 0.299 ENSMUST00000118162.1
ENSMUST00000140599.2
ENSMUST00000120798.1
Zfp473


zinc finger protein 473


chr3_-_146108047 0.296 ENSMUST00000160285.1
Wdr63
WD repeat domain 63
chr2_+_145785980 0.295 ENSMUST00000110005.1
ENSMUST00000094480.4
Rin2

Ras and Rab interactor 2

chr2_-_120609319 0.295 ENSMUST00000102497.3
Lrrc57
leucine rich repeat containing 57
chr17_-_87446854 0.291 ENSMUST00000040440.6
Calm2
calmodulin 2
chr12_+_72761211 0.286 ENSMUST00000021514.8
Ppm1a
protein phosphatase 1A, magnesium dependent, alpha isoform
chr5_-_5559501 0.283 ENSMUST00000119521.1
Gtpbp10
GTP-binding protein 10 (putative)
chr6_-_39725193 0.280 ENSMUST00000101497.3
Braf
Braf transforming gene
chr8_+_92674289 0.278 ENSMUST00000034185.6
Irx6
Iroquois related homeobox 6 (Drosophila)
chr4_+_32238950 0.274 ENSMUST00000037416.6
Bach2
BTB and CNC homology 2
chr13_-_54688184 0.272 ENSMUST00000150806.1
ENSMUST00000125927.1
Rnf44

ring finger protein 44

chr11_+_20631956 0.269 ENSMUST00000109586.2
Sertad2
SERTA domain containing 2
chr8_-_81014866 0.266 ENSMUST00000042724.6
Usp38
ubiquitin specific peptidase 38
chrX_-_8145679 0.261 ENSMUST00000115619.1
ENSMUST00000115617.3
ENSMUST00000040010.3
Rbm3


RNA binding motif protein 3


chr3_-_138143352 0.260 ENSMUST00000098580.2
Mttp
microsomal triglyceride transfer protein
chr7_+_92741603 0.260 ENSMUST00000032879.7
Rab30
RAB30, member RAS oncogene family
chr11_-_102185239 0.259 ENSMUST00000021297.5
Lsm12
LSM12 homolog (S. cerevisiae)
chr16_+_22009471 0.258 ENSMUST00000023561.7
Senp2
SUMO/sentrin specific peptidase 2
chr16_-_16829276 0.258 ENSMUST00000023468.5
Spag6
sperm associated antigen 6
chr8_-_69625503 0.256 ENSMUST00000121886.1
Zfp868
zinc finger protein 868
chr16_+_5050012 0.256 ENSMUST00000052449.5
Ubn1
ubinuclein 1
chr2_-_120609283 0.252 ENSMUST00000102496.1
Lrrc57
leucine rich repeat containing 57
chr7_+_125707893 0.250 ENSMUST00000069660.6
ENSMUST00000142464.1
D430042O09Rik

RIKEN cDNA D430042O09 gene

chr15_+_59648644 0.247 ENSMUST00000118228.1
Trib1
tribbles homolog 1 (Drosophila)
chr2_+_23156369 0.244 ENSMUST00000028117.3
Yme1l1
YME1-like 1 (S. cerevisiae)
chr15_-_12321899 0.244 ENSMUST00000180521.1
1810049J17Rik
RIKEN cDNA 1810049J17 gene
chr17_+_29660595 0.244 ENSMUST00000024816.6
Cmtr1
cap methyltransferase 1
chr10_+_42583787 0.243 ENSMUST00000105497.1
ENSMUST00000144806.1
Ostm1

osteopetrosis associated transmembrane protein 1

chr13_-_99516537 0.240 ENSMUST00000064762.4
Map1b
microtubule-associated protein 1B
chr5_+_123394782 0.240 ENSMUST00000111596.1
ENSMUST00000068237.5
Mlxip

MLX interacting protein

chr8_+_92674826 0.236 ENSMUST00000167261.2
Irx6
Iroquois related homeobox 6 (Drosophila)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 8.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.7 3.0 GO:1902724 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.7 2.0 GO:0072284 cervix development(GO:0060067) metanephric S-shaped body morphogenesis(GO:0072284) anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.6 1.9 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.6 3.8 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.5 2.5 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
0.4 1.3 GO:0060364 frontal suture morphogenesis(GO:0060364)
0.4 1.7 GO:0042414 epinephrine metabolic process(GO:0042414)
0.4 1.9 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.3 1.0 GO:0035973 aggrephagy(GO:0035973)
0.3 4.6 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.3 1.2 GO:0060578 extraocular skeletal muscle development(GO:0002074) subthalamic nucleus development(GO:0021763) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.3 5.6 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.3 1.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.3 0.8 GO:0010958 regulation of amino acid import(GO:0010958)
0.3 1.0 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.3 1.8 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.2 2.2 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.2 0.7 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.2 1.9 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.2 1.9 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.2 2.5 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.2 3.5 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.2 3.1 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.2 0.7 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.2 0.9 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.2 1.7 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.2 1.5 GO:0030432 peristalsis(GO:0030432)
0.2 1.2 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.2 0.3 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.2 0.5 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.1 0.4 GO:0061303 hard palate development(GO:0060022) soft palate development(GO:0060023) cornea development in camera-type eye(GO:0061303)
0.1 1.8 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.1 0.7 GO:0021764 amygdala development(GO:0021764)
0.1 0.6 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.1 1.7 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 0.7 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.1 0.8 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 1.2 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.1 0.5 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.1 0.4 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 1.3 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.7 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.1 0.3 GO:0097278 transforming growth factor beta activation(GO:0036363) complement-dependent cytotoxicity(GO:0097278)
0.1 1.0 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 0.6 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 0.5 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 1.0 GO:0006824 cobalt ion transport(GO:0006824)
0.1 0.6 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 1.6 GO:0072520 seminiferous tubule development(GO:0072520)
0.1 0.4 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.1 0.5 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.2 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.5 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.4 GO:0060279 positive regulation of ovulation(GO:0060279)
0.1 0.5 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.2 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1 2.1 GO:0001709 cell fate determination(GO:0001709)
0.1 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.1 0.2 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1 0.4 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.4 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.5 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.1 1.7 GO:0016572 histone phosphorylation(GO:0016572)
0.1 0.3 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.3 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.1 0.8 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.1 GO:0043622 cortical microtubule organization(GO:0043622)
0.0 0.3 GO:0018377 N-terminal protein myristoylation(GO:0006499) protein myristoylation(GO:0018377)
0.0 0.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.3 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.1 GO:2000850 negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.0 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949) tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.0 0.5 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.2 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.0 0.2 GO:0090164 asymmetric Golgi ribbon formation(GO:0090164)
0.0 0.3 GO:0061072 iris morphogenesis(GO:0061072)
0.0 0.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.7 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.3 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.6 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.3 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.2 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.4 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.3 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.9 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 1.6 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 0.1 GO:0019046 release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
0.0 0.1 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 1.8 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.2 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.8 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 1.5 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.3 GO:0032875 regulation of DNA endoreduplication(GO:0032875) DNA endoreduplication(GO:0042023)
0.0 0.1 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.1 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.0 0.7 GO:0035329 hippo signaling(GO:0035329)
0.0 0.6 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 1.1 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.1 GO:0048296 isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296)
0.0 0.1 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.5 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.4 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.2 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.4 GO:0021511 spinal cord patterning(GO:0021511)
0.0 0.2 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.1 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.2 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.3 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 0.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.3 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 1.6 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.7 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.1 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.0 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.0 0.5 GO:0048536 spleen development(GO:0048536)
0.0 0.2 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.2 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.3 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 2.2 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.1 GO:1902741 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0 0.0 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 1.2 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 0.1 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
0.0 0.0 GO:1904995 regulation of leukocyte tethering or rolling(GO:1903236) negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0 0.1 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.2 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.0 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.1 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.6 1.8 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.6 1.7 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.4 4.8 GO:1990023 mitotic spindle midzone(GO:1990023)
0.3 0.9 GO:1990423 RZZ complex(GO:1990423)
0.3 0.8 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.2 0.8 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.2 1.6 GO:0030478 actin cap(GO:0030478)
0.2 2.8 GO:0030008 TRAPP complex(GO:0030008)
0.2 1.2 GO:0001940 male pronucleus(GO:0001940)
0.1 0.9 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.7 GO:0070652 HAUS complex(GO:0070652)
0.1 0.4 GO:0098536 deuterosome(GO:0098536)
0.1 0.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.4 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 1.1 GO:0051233 spindle midzone(GO:0051233)
0.1 0.9 GO:0031045 dense core granule(GO:0031045)
0.1 0.6 GO:0071437 invadopodium(GO:0071437)
0.1 0.7 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.4 GO:0033503 HULC complex(GO:0033503)
0.0 1.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.6 GO:0097546 ciliary base(GO:0097546)
0.0 2.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 1.2 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) Holliday junction resolvase complex(GO:0048476)
0.0 0.7 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.4 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.4 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.1 GO:0098842 postsynaptic early endosome(GO:0098842)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 2.1 GO:0005844 polysome(GO:0005844)
0.0 0.3 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.0 0.2 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.1 GO:0000235 astral microtubule(GO:0000235)
0.0 0.1 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 1.2 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 2.2 GO:0016605 PML body(GO:0016605)
0.0 0.7 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.3 GO:0030904 retromer complex(GO:0030904)
0.0 3.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.4 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.3 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 1.2 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.5 GO:0034702 ion channel complex(GO:0034702)
0.0 0.6 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.3 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 2.7 GO:0005769 early endosome(GO:0005769)
0.0 0.0 GO:0097542 ciliary tip(GO:0097542)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 6.0 GO:0016604 nuclear body(GO:0016604)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 5.6 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.8 3.8 GO:0043515 kinetochore binding(GO:0043515)
0.5 1.5 GO:0004994 somatostatin receptor activity(GO:0004994)
0.5 3.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.3 1.7 GO:0035240 dopamine binding(GO:0035240)
0.3 0.9 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.3 0.8 GO:0019776 Atg8 ligase activity(GO:0019776)
0.2 1.2 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.2 1.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 1.8 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.2 1.6 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.2 0.2 GO:0000992 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.2 1.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.2 2.5 GO:0003680 AT DNA binding(GO:0003680)
0.2 0.3 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.1 1.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.8 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 1.0 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
0.1 1.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 2.4 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.1 0.5 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.4 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.1 0.5 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.1 1.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.3 GO:0031996 thioesterase binding(GO:0031996)
0.1 18.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 2.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.5 GO:0042731 PH domain binding(GO:0042731)
0.1 0.3 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.7 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.3 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.1 0.6 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 2.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 2.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 2.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.6 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.2 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 2.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.9 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.3 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 2.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.9 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.5 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 1.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 1.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 1.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.5 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.3 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.0 0.1 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 1.2 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.5 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.9 GO:0005112 Notch binding(GO:0005112)
0.0 3.7 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 1.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.7 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.9 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.7 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.0 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.0 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.1 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.1 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.0 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.0 0.2 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.0 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.6 GO:0004497 monooxygenase activity(GO:0004497)
0.0 0.2 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.4 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.6 ST_STAT3_PATHWAY STAT3 Pathway
0.2 2.3 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 4.8 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 4.9 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.1 4.7 PID_PLK1_PATHWAY PLK1 signaling events
0.0 1.8 PID_BARD1_PATHWAY BARD1 signaling events
0.0 1.4 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 1.5 ST_ADRENERGIC Adrenergic Pathway
0.0 0.5 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.0 0.4 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 2.9 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 2.2 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.1 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 1.3 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.7 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 2.1 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 0.7 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.8 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.7 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 0.1 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 0.1 PID_MYC_PATHWAY C-MYC pathway
0.0 0.8 PID_CDC42_PATHWAY CDC42 signaling events
0.0 0.4 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.6 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.5 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.0 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.2 2.5 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.2 1.8 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.2 1.7 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 0.9 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 3.9 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 2.4 REACTOME_KINESINS Genes involved in Kinesins
0.1 2.5 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.2 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 0.8 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 2.4 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 2.6 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 0.5 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.3 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.9 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.8 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.7 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.9 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.3 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 2.1 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.0 1.6 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.5 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.1 REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.6 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.5 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.6 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.6 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.2 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.8 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.7 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes