Motif ID: Dmc1

Z-value: 1.108


Transcription factors associated with Dmc1:

Gene SymbolEntrez IDGene Name
Dmc1 ENSMUSG00000022429.10 Dmc1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Dmc1mm10_v2_chr15_-_79605084_796051140.221.8e-01Click!


Activity profile for motif Dmc1.

activity profile for motif Dmc1


Sorted Z-values histogram for motif Dmc1

Sorted Z-values for motif Dmc1



Network of associatons between targets according to the STRING database.



First level regulatory network of Dmc1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_14229390 5.598 ENSMUST00000028045.2
Mrc1
mannose receptor, C type 1
chr16_-_43979050 4.446 ENSMUST00000165648.1
ENSMUST00000036321.7
Zdhhc23

zinc finger, DHHC domain containing 23

chr18_+_61105561 4.338 ENSMUST00000025523.6
Csf1r
colony stimulating factor 1 receptor
chr17_+_55445375 3.510 ENSMUST00000133899.1
ENSMUST00000086878.3
St6gal2

beta galactoside alpha 2,6 sialyltransferase 2

chr10_-_117282262 3.220 ENSMUST00000092163.7
Lyz2
lysozyme 2
chr4_+_128058962 3.210 ENSMUST00000184063.1
Csmd2
CUB and Sushi multiple domains 2
chr8_+_66386292 3.202 ENSMUST00000039540.5
ENSMUST00000110253.2
March1

membrane-associated ring finger (C3HC4) 1

chr7_-_14562171 3.189 ENSMUST00000181796.1
Vmn1r90
vomeronasal 1 receptor 90
chr7_-_45103747 3.104 ENSMUST00000003512.7
Fcgrt
Fc receptor, IgG, alpha chain transporter
chr3_+_95526777 3.033 ENSMUST00000015667.2
ENSMUST00000116304.2
Ctss

cathepsin S

chr14_+_75955003 2.856 ENSMUST00000050120.2
Kctd4
potassium channel tetramerisation domain containing 4
chr2_-_104257400 2.845 ENSMUST00000141159.1
D430041D05Rik
RIKEN cDNA D430041D05 gene
chr1_-_38821215 2.761 ENSMUST00000039612.4
Lonrf2
LON peptidase N-terminal domain and ring finger 2
chr4_+_57845240 2.616 ENSMUST00000102903.1
ENSMUST00000107598.3
Akap2

A kinase (PRKA) anchor protein 2

chr4_+_126609818 2.315 ENSMUST00000097886.3
ENSMUST00000164362.1
5730409E04Rik

RIKEN cDNA 5730409E04Rik gene

chr18_+_37484955 2.304 ENSMUST00000053856.4
Pcdhb17
protocadherin beta 17
chr4_-_141598206 2.252 ENSMUST00000131317.1
ENSMUST00000006381.4
ENSMUST00000129602.1
Fblim1


filamin binding LIM protein 1


chr2_+_164960809 2.176 ENSMUST00000124372.1
Slc12a5
solute carrier family 12, member 5
chrX_-_160994665 2.172 ENSMUST00000087104.4
Cdkl5
cyclin-dependent kinase-like 5
chr5_+_37185897 2.171 ENSMUST00000094840.3
Gm1043
predicted gene 1043
chr14_+_75136326 2.164 ENSMUST00000145303.1
Lcp1
lymphocyte cytosolic protein 1
chr5_+_112255813 2.149 ENSMUST00000031286.6
ENSMUST00000131673.1
ENSMUST00000112375.1
Crybb1


crystallin, beta B1


chr15_+_21111452 2.140 ENSMUST00000075132.6
Cdh12
cadherin 12
chr9_+_21032038 2.013 ENSMUST00000019616.4
Icam5
intercellular adhesion molecule 5, telencephalin
chr10_-_125308809 1.933 ENSMUST00000105257.2
Slc16a7
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr19_-_57197556 1.929 ENSMUST00000099294.2
Ablim1
actin-binding LIM protein 1
chr5_-_92348871 1.894 ENSMUST00000038816.6
ENSMUST00000118006.1
Cxcl10

chemokine (C-X-C motif) ligand 10

chr4_+_42466752 1.885 ENSMUST00000179734.1
Gm2163
predicted gene 2163
chr19_-_57197435 1.871 ENSMUST00000111550.1
Ablim1
actin-binding LIM protein 1
chr6_+_135362931 1.870 ENSMUST00000032330.9
Emp1
epithelial membrane protein 1
chr18_+_37421418 1.846 ENSMUST00000053073.4
Pcdhb11
protocadherin beta 11
chr17_+_70561739 1.807 ENSMUST00000097288.2
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr18_+_23415400 1.804 ENSMUST00000115832.2
ENSMUST00000047954.7
Dtna

dystrobrevin alpha

chr6_+_148047259 1.794 ENSMUST00000032443.7
Far2
fatty acyl CoA reductase 2
chr19_-_57197496 1.766 ENSMUST00000111544.1
Ablim1
actin-binding LIM protein 1
chr19_-_57197377 1.757 ENSMUST00000111546.1
Ablim1
actin-binding LIM protein 1
chr16_-_17144415 1.745 ENSMUST00000115709.1
Ccdc116
coiled-coil domain containing 116
chr11_+_82035569 1.731 ENSMUST00000000193.5
Ccl2
chemokine (C-C motif) ligand 2
chr18_+_37447641 1.716 ENSMUST00000052387.3
Pcdhb14
protocadherin beta 14
chr13_-_92030897 1.681 ENSMUST00000149630.1
Rasgrf2
RAS protein-specific guanine nucleotide-releasing factor 2
chr10_-_70592782 1.631 ENSMUST00000162251.1
Phyhipl
phytanoyl-CoA hydroxylase interacting protein-like
chr5_+_107437908 1.591 ENSMUST00000094541.2
Btbd8
BTB (POZ) domain containing 8
chr4_-_141606011 1.559 ENSMUST00000123150.1
ENSMUST00000133874.1
ENSMUST00000136831.1
ENSMUST00000130181.1
ENSMUST00000105785.2
Fblim1




filamin binding LIM protein 1




chr11_-_75796048 1.532 ENSMUST00000021209.7
Doc2b
double C2, beta
chr6_+_86195214 1.522 ENSMUST00000032066.9
Tgfa
transforming growth factor alpha
chr12_-_84698769 1.518 ENSMUST00000095550.2
Syndig1l
synapse differentiation inducing 1 like
chr4_+_148602527 1.502 ENSMUST00000105701.2
ENSMUST00000052060.6
Masp2

mannan-binding lectin serine peptidase 2

chr18_+_37513652 1.490 ENSMUST00000061405.4
Pcdhb21
protocadherin beta 21
chr2_+_155940728 1.467 ENSMUST00000109629.1
Gm15557
predicted gene 15557
chr7_-_43313063 1.458 ENSMUST00000135130.1
ENSMUST00000139061.1
Zfp715

zinc finger protein 715

chr18_+_61105844 1.453 ENSMUST00000115268.3
Csf1r
colony stimulating factor 1 receptor
chr12_+_103434211 1.429 ENSMUST00000079294.5
ENSMUST00000076788.5
ENSMUST00000076702.5
ENSMUST00000066701.6
ENSMUST00000085065.5
ENSMUST00000140838.1
Ifi27





interferon, alpha-inducible protein 27





chr4_-_42856771 1.419 ENSMUST00000107981.1
Gm12394
predicted gene 12394
chr18_-_46311891 1.419 ENSMUST00000072835.6
Ccdc112
coiled-coil domain containing 112
chr13_-_67755132 1.402 ENSMUST00000091520.6
Zfp85-rs1
zinc finger protein 85, related sequence 1
chr9_+_107935876 1.385 ENSMUST00000035700.8
Camkv
CaM kinase-like vesicle-associated
chr2_-_144527341 1.365 ENSMUST00000163701.1
ENSMUST00000081982.5
Dzank1

double zinc ribbon and ankyrin repeat domains 1

chr8_+_114205590 1.325 ENSMUST00000049509.6
ENSMUST00000150963.1
Vat1l

vesicle amine transport protein 1 homolog-like (T. californica)

chr6_-_136875794 1.323 ENSMUST00000032342.1
Mgp
matrix Gla protein
chr13_-_67081503 1.301 ENSMUST00000109742.3
Zfp708
zinc finger protein 708
chr13_-_67755192 1.285 ENSMUST00000144183.1
Zfp85-rs1
zinc finger protein 85, related sequence 1
chr1_-_150392719 1.280 ENSMUST00000006167.6
ENSMUST00000094477.2
ENSMUST00000097547.3
BC003331


cDNA sequence BC003331


chr3_+_66219909 1.257 ENSMUST00000029421.5
Ptx3
pentraxin related gene
chrX_+_73483602 1.254 ENSMUST00000033741.8
ENSMUST00000169489.1
Bgn

biglycan

chr12_+_108410625 1.252 ENSMUST00000109857.1
Eml1
echinoderm microtubule associated protein like 1
chr12_-_31499541 1.251 ENSMUST00000101499.3
ENSMUST00000064240.6
ENSMUST00000085487.5
Cbll1


Casitas B-lineage lymphoma-like 1


chr1_-_173942445 1.244 ENSMUST00000042228.8
ENSMUST00000081216.5
ENSMUST00000129829.1
ENSMUST00000123708.1
ENSMUST00000111210.2
Ifi203



Mndal
interferon activated gene 203



myeloid nuclear differentiation antigen like
chr7_-_27337667 1.241 ENSMUST00000038618.6
ENSMUST00000108369.2
Ltbp4

latent transforming growth factor beta binding protein 4

chr2_+_122147680 1.228 ENSMUST00000102476.4
B2m
beta-2 microglobulin
chr12_+_108410542 1.221 ENSMUST00000054955.7
Eml1
echinoderm microtubule associated protein like 1
chr4_+_57568144 1.208 ENSMUST00000102904.3
Palm2
paralemmin 2
chr15_+_103453782 1.202 ENSMUST00000047405.7
Nckap1l
NCK associated protein 1 like
chr15_-_43869993 1.189 ENSMUST00000067469.4
Tmem74
transmembrane protein 74
chr2_+_130406478 1.184 ENSMUST00000055421.4
Tmem239
transmembrane 239
chr1_-_150393024 1.166 ENSMUST00000097546.2
ENSMUST00000111913.2
BC003331

cDNA sequence BC003331

chr2_+_130405256 1.159 ENSMUST00000110281.1
ENSMUST00000028898.3
1700020A23Rik

RIKEN cDNA 1700020A23 gene

chrX_-_9256899 1.158 ENSMUST00000115553.2
Gm14862
predicted gene 14862
chr11_-_53707269 1.147 ENSMUST00000124352.1
ENSMUST00000020649.7
Rad50

RAD50 homolog (S. cerevisiae)

chr10_-_33624587 1.136 ENSMUST00000160299.1
ENSMUST00000019920.6
Clvs2

clavesin 2

chr18_+_36939178 1.131 ENSMUST00000115662.2
Pcdha2
protocadherin alpha 2
chr8_+_104340594 1.130 ENSMUST00000034343.4
Cmtm3
CKLF-like MARVEL transmembrane domain containing 3
chr11_+_116532441 1.118 ENSMUST00000106386.1
ENSMUST00000145737.1
ENSMUST00000155102.1
ENSMUST00000063446.6
Sphk1



sphingosine kinase 1



chr10_+_116177351 1.116 ENSMUST00000155606.1
ENSMUST00000128399.1
Ptprr

protein tyrosine phosphatase, receptor type, R

chr10_-_30655859 1.113 ENSMUST00000092610.4
Ncoa7
nuclear receptor coactivator 7
chr5_-_75978447 1.109 ENSMUST00000113516.1
Kdr
kinase insert domain protein receptor
chr8_-_46080284 1.101 ENSMUST00000177186.1
Snx25
sorting nexin 25
chr5_+_143651222 1.092 ENSMUST00000110727.1
Cyth3
cytohesin 3
chr6_-_48708206 1.084 ENSMUST00000119315.1
ENSMUST00000053661.4
Gimap6

GTPase, IMAP family member 6

chr10_+_62071014 1.068 ENSMUST00000053865.5
Gm5424
predicted gene 5424
chr2_-_59160644 1.065 ENSMUST00000077687.5
Ccdc148
coiled-coil domain containing 148
chr4_+_95967205 1.059 ENSMUST00000030306.7
Hook1
hook homolog 1 (Drosophila)
chr5_-_41844168 1.021 ENSMUST00000050556.7
Bod1l
biorientation of chromosomes in cell division 1-like
chr4_+_58943575 1.017 ENSMUST00000107554.1
Zkscan16
zinc finger with KRAB and SCAN domains 16
chr1_-_79440039 0.996 ENSMUST00000049972.4
Scg2
secretogranin II
chr4_-_134095078 0.996 ENSMUST00000000696.6
Cd52
CD52 antigen
chr14_-_29721835 0.991 ENSMUST00000022567.7
Cacna2d3
calcium channel, voltage-dependent, alpha2/delta subunit 3
chr9_+_3335470 0.985 ENSMUST00000053407.5
Alkbh8
alkB, alkylation repair homolog 8 (E. coli)
chr13_-_62371936 0.982 ENSMUST00000107989.3
Gm3604
predicted gene 3604
chr18_+_37320374 0.981 ENSMUST00000078271.2
Pcdhb5
protocadherin beta 5
chr8_+_95703037 0.979 ENSMUST00000073139.7
ENSMUST00000080666.7
Ndrg4

N-myc downstream regulated gene 4

chrX_+_155262443 0.973 ENSMUST00000026324.9
Acot9
acyl-CoA thioesterase 9
chr15_+_34306666 0.968 ENSMUST00000163455.2
ENSMUST00000022947.5
Matn2

matrilin 2

chr12_+_117516479 0.963 ENSMUST00000109691.2
Rapgef5
Rap guanine nucleotide exchange factor (GEF) 5
chr8_-_9976294 0.960 ENSMUST00000095476.4
Lig4
ligase IV, DNA, ATP-dependent
chr5_+_136919137 0.953 ENSMUST00000181045.1
4933404O12Rik
RIKEN cDNA 4933404O12 gene
chr4_+_41941572 0.941 ENSMUST00000108028.2
ENSMUST00000153997.1
Gm20878

predicted gene, 20878

chr5_-_104021919 0.941 ENSMUST00000031251.9
Hsd17b11
hydroxysteroid (17-beta) dehydrogenase 11
chr19_+_40612392 0.931 ENSMUST00000134063.1
Entpd1
ectonucleoside triphosphate diphosphohydrolase 1
chr19_+_53529100 0.920 ENSMUST00000038287.6
Dusp5
dual specificity phosphatase 5
chr19_-_29805507 0.916 ENSMUST00000175726.1
9930021J03Rik
RIKEN cDNA 9930021J03 gene
chr7_+_35119285 0.912 ENSMUST00000042985.9
Cebpa
CCAAT/enhancer binding protein (C/EBP), alpha
chr15_+_83791939 0.894 ENSMUST00000172115.1
ENSMUST00000172398.1
Mpped1

metallophosphoesterase domain containing 1

chr15_+_12117848 0.885 ENSMUST00000128475.1
ENSMUST00000134277.1
Zfr

zinc finger RNA binding protein

chr15_+_79108911 0.879 ENSMUST00000040320.8
Micall1
microtubule associated monooxygenase, calponin and LIM domain containing -like 1
chr4_+_46039202 0.865 ENSMUST00000156200.1
Tmod1
tropomodulin 1
chr9_-_103222063 0.853 ENSMUST00000170904.1
Trf
transferrin
chr1_+_150392794 0.850 ENSMUST00000124973.2
Tpr
translocated promoter region
chr15_+_33083110 0.847 ENSMUST00000042167.9
Cpq
carboxypeptidase Q
chr10_-_75797528 0.846 ENSMUST00000120177.1
Gstt1
glutathione S-transferase, theta 1
chr19_-_4283033 0.842 ENSMUST00000167215.1
ENSMUST00000056888.6
Ankrd13d

ankyrin repeat domain 13 family, member D

chr18_+_37300799 0.838 ENSMUST00000051754.1
Pcdhb3
protocadherin beta 3
chr10_+_105841064 0.837 ENSMUST00000020049.8
Ccdc59
coiled-coil domain containing 59
chrX_+_96713486 0.827 ENSMUST00000033554.4
Gpr165
G protein-coupled receptor 165
chr10_+_20312461 0.820 ENSMUST00000092678.3
ENSMUST00000043881.5
Bclaf1

BCL2-associated transcription factor 1

chr2_+_69722797 0.817 ENSMUST00000090858.3
Ppig
peptidyl-prolyl isomerase G (cyclophilin G)
chr3_-_92083132 0.813 ENSMUST00000058150.6
Lor
loricrin
chr10_-_26373956 0.810 ENSMUST00000105519.3
ENSMUST00000040219.6
L3mbtl3

l(3)mbt-like 3 (Drosophila)

chr1_+_163779575 0.806 ENSMUST00000027877.6
ENSMUST00000077642.5
Kifap3

kinesin-associated protein 3

chr8_+_58911755 0.789 ENSMUST00000062978.6
BC030500
cDNA sequence BC030500
chr1_+_74375203 0.775 ENSMUST00000027368.5
Slc11a1
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
chr16_+_72663143 0.768 ENSMUST00000023600.7
Robo1
roundabout homolog 1 (Drosophila)
chr4_+_12906838 0.766 ENSMUST00000143186.1
ENSMUST00000183345.1
Triqk

triple QxxK/R motif containing

chr1_+_95313607 0.763 ENSMUST00000059975.6
Fam174a
family with sequence similarity 174, member A
chr15_+_102102926 0.751 ENSMUST00000169627.1
ENSMUST00000046144.9
Tenc1

tensin like C1 domain-containing phosphatase

chr18_-_82406777 0.736 ENSMUST00000065224.6
Galr1
galanin receptor 1
chr11_+_119393060 0.734 ENSMUST00000131035.2
ENSMUST00000093902.5
Rnf213

ring finger protein 213

chr15_-_39112642 0.733 ENSMUST00000022908.8
Slc25a32
solute carrier family 25, member 32
chr9_+_75441518 0.726 ENSMUST00000048937.4
Leo1
Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr4_+_146654927 0.725 ENSMUST00000070932.3
Gm13248
predicted gene 13248
chrX_-_36864238 0.722 ENSMUST00000115249.3
ENSMUST00000115248.3
C330007P06Rik

RIKEN cDNA C330007P06 gene

chr11_-_100472725 0.698 ENSMUST00000056665.3
Klhl11
kelch-like 11
chr12_+_33429605 0.693 ENSMUST00000020877.7
Twistnb
TWIST neighbor
chr7_-_92637079 0.690 ENSMUST00000056106.7
ENSMUST00000118157.1
Ankrd42

ankyrin repeat domain 42

chr10_-_81291227 0.677 ENSMUST00000045744.6
Tjp3
tight junction protein 3
chr19_-_3907087 0.672 ENSMUST00000001801.4
Tcirg1
T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3
chr5_-_104021799 0.669 ENSMUST00000119025.1
Hsd17b11
hydroxysteroid (17-beta) dehydrogenase 11
chr19_+_42247544 0.668 ENSMUST00000122375.1
Golga7b
golgi autoantigen, golgin subfamily a, 7B
chr10_+_69534039 0.665 ENSMUST00000182557.1
Ank3
ankyrin 3, epithelial
chr18_-_15718046 0.664 ENSMUST00000053017.6
Chst9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr19_-_3906991 0.658 ENSMUST00000126070.2
Tcirg1
T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3
chr16_+_33062512 0.648 ENSMUST00000023497.2
Lmln
leishmanolysin-like (metallopeptidase M8 family)
chr3_-_127553233 0.646 ENSMUST00000029588.5
Larp7
La ribonucleoprotein domain family, member 7
chr1_-_52232296 0.642 ENSMUST00000114512.1
Gls
glutaminase
chr5_+_114896936 0.636 ENSMUST00000031542.9
ENSMUST00000146072.1
ENSMUST00000150361.1
Oasl2


2'-5' oligoadenylate synthetase-like 2


chr2_-_6884940 0.636 ENSMUST00000183091.1
ENSMUST00000182851.1
Celf2

CUGBP, Elav-like family member 2

chr6_+_72598475 0.635 ENSMUST00000070597.6
ENSMUST00000176364.1
ENSMUST00000176168.1
Retsat


retinol saturase (all trans retinol 13,14 reductase)


chr4_+_118961578 0.632 ENSMUST00000058651.4
Lao1
L-amino acid oxidase 1
chr12_+_109540979 0.620 ENSMUST00000129245.1
ENSMUST00000143836.1
ENSMUST00000124106.1
Meg3


maternally expressed 3


chr4_+_108879130 0.615 ENSMUST00000106651.2
Rab3b
RAB3B, member RAS oncogene family
chr19_+_8929628 0.614 ENSMUST00000096241.4
Eml3
echinoderm microtubule associated protein like 3
chr12_+_4133394 0.613 ENSMUST00000152065.1
ENSMUST00000127756.1
Adcy3

adenylate cyclase 3

chr15_-_58823530 0.604 ENSMUST00000072113.5
Tmem65
transmembrane protein 65
chr17_+_55952623 0.602 ENSMUST00000003274.6
Ebi3
Epstein-Barr virus induced gene 3
chr13_-_115101909 0.602 ENSMUST00000061673.7
Itga1
integrin alpha 1
chr7_+_90442729 0.599 ENSMUST00000061767.4
ENSMUST00000107206.1
Crebzf

CREB/ATF bZIP transcription factor

chr19_-_37176055 0.597 ENSMUST00000142973.1
ENSMUST00000154376.1
Cpeb3

cytoplasmic polyadenylation element binding protein 3

chr8_+_15011025 0.594 ENSMUST00000069399.6
Kbtbd11
kelch repeat and BTB (POZ) domain containing 11
chr12_-_84876479 0.589 ENSMUST00000163189.1
ENSMUST00000110254.2
ENSMUST00000002073.6
Ltbp2


latent transforming growth factor beta binding protein 2


chr18_+_37307445 0.587 ENSMUST00000056712.2
Pcdhb4
protocadherin beta 4
chrX_+_53607918 0.581 ENSMUST00000114827.1
Cxx1c
CAAX box 1C
chr5_+_23850590 0.580 ENSMUST00000181574.1
2700038G22Rik
RIKEN cDNA 2700038G22 gene
chr19_-_50678485 0.572 ENSMUST00000111756.3
Sorcs1
VPS10 domain receptor protein SORCS 1
chr8_-_58911627 0.563 ENSMUST00000077447.4
Galntl6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
chr2_-_6884975 0.555 ENSMUST00000114924.3
ENSMUST00000170438.1
ENSMUST00000114934.4
Celf2


CUGBP, Elav-like family member 2


chr1_-_134955847 0.554 ENSMUST00000168381.1
Ppp1r12b
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chrX_+_23693043 0.542 ENSMUST00000035766.6
ENSMUST00000101670.2
Wdr44

WD repeat domain 44

chrX_-_143393893 0.539 ENSMUST00000166406.2
Chrdl1
chordin-like 1
chr16_+_35022394 0.539 ENSMUST00000061156.8
Ptplb
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b
chr1_+_174501796 0.530 ENSMUST00000030039.7
Fmn2
formin 2
chr1_+_183388981 0.528 ENSMUST00000097043.5
Taf1a
TATA box binding protein (Tbp)-associated factor, RNA polymerase I, A
chr3_-_57301919 0.527 ENSMUST00000029376.8
Tm4sf1
transmembrane 4 superfamily member 1
chr7_+_99267428 0.527 ENSMUST00000068973.4
ENSMUST00000122101.1
Map6

microtubule-associated protein 6

chr5_-_17888884 0.519 ENSMUST00000169095.1
Cd36
CD36 antigen
chr4_-_56990332 0.516 ENSMUST00000053681.5
Frrs1l
ferric-chelate reductase 1 like
chr13_+_62129894 0.514 ENSMUST00000099449.3
Zfp808
zinc finger protein 80
chr2_-_175141999 0.513 ENSMUST00000109062.1
ENSMUST00000109059.1
ENSMUST00000109060.1
Gm14399


predicted gene 14399


chr9_-_110476637 0.504 ENSMUST00000111934.1
ENSMUST00000068025.6
Klhl18

kelch-like 18

chr4_-_137357661 0.503 ENSMUST00000030417.9
Cdc42
cell division cycle 42
chr3_+_146852359 0.492 ENSMUST00000038090.5
ENSMUST00000170055.1
Ttll7

tubulin tyrosine ligase-like family, member 7

chr5_-_65335597 0.492 ENSMUST00000172660.1
ENSMUST00000172732.1
ENSMUST00000031092.8
Rfc1


replication factor C (activator 1) 1


chr8_+_71887264 0.481 ENSMUST00000034259.7
Zfp709
zinc finger protein 709
chr1_+_179961110 0.480 ENSMUST00000076687.5
ENSMUST00000097450.3
Cdc42bpa

CDC42 binding protein kinase alpha

chrX_+_42526585 0.480 ENSMUST00000101619.3
Gm10483
predicted gene 10483
chr8_-_71395794 0.478 ENSMUST00000049184.7
Ushbp1
Usher syndrome 1C binding protein 1
chr1_+_75375271 0.477 ENSMUST00000087122.5
Speg
SPEG complex locus
chr16_-_30550560 0.473 ENSMUST00000140402.1
Tmem44
transmembrane protein 44
chr5_+_137569851 0.472 ENSMUST00000031729.8
Tfr2
transferrin receptor 2
chr3_-_121815212 0.472 ENSMUST00000029770.5
Abcd3
ATP-binding cassette, sub-family D (ALD), member 3
chr5_-_65335564 0.454 ENSMUST00000172780.1
Rfc1
replication factor C (activator 1) 1
chr13_-_92483996 0.452 ENSMUST00000040106.7
Fam151b
family with sequence similarity 151, member B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.8 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
1.1 3.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.6 1.7 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.5 2.7 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.5 2.0 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.4 1.6 GO:0006710 androgen catabolic process(GO:0006710)
0.4 1.2 GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.4 2.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.4 1.8 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.3 2.6 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.3 0.8 GO:0032240 RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.3 0.8 GO:0042196 dichloromethane metabolic process(GO:0018900) chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197)
0.3 1.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.3 0.8 GO:0032632 interleukin-3 production(GO:0032632)
0.3 0.8 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.3 3.8 GO:0033623 regulation of integrin activation(GO:0033623)
0.3 1.3 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.2 1.5 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
0.2 0.7 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
0.2 1.1 GO:0000019 regulation of mitotic recombination(GO:0000019) telomeric 3' overhang formation(GO:0031860)
0.2 1.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 0.6 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.2 3.5 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.2 1.1 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.2 3.0 GO:0030574 collagen catabolic process(GO:0030574)
0.2 0.5 GO:0070649 meiotic chromosome movement towards spindle pole(GO:0016344) formin-nucleated actin cable assembly(GO:0070649)
0.2 5.1 GO:0018345 protein palmitoylation(GO:0018345)
0.2 0.5 GO:0070543 response to linoleic acid(GO:0070543)
0.2 0.9 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.2 3.2 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.2 5.6 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.2 1.0 GO:0002681 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153) double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.2 0.5 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.2 0.9 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
0.2 1.4 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.2 0.6 GO:0097494 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944) regulation of vesicle size(GO:0097494)
0.1 2.2 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.8 GO:0006590 thyroid hormone generation(GO:0006590)
0.1 1.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 1.8 GO:0070842 aggresome assembly(GO:0070842)
0.1 1.2 GO:0031424 keratinization(GO:0031424)
0.1 0.7 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.6 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.1 GO:0002730 regulation of dendritic cell cytokine production(GO:0002730)
0.1 0.6 GO:0008355 olfactory learning(GO:0008355)
0.1 1.3 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 1.5 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.3 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.1 0.3 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 1.1 GO:0046512 sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.1 0.3 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.1 0.2 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.1 1.9 GO:0032060 bleb assembly(GO:0032060)
0.1 1.5 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 1.7 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.1 1.1 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 1.0 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.9 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 0.4 GO:2000319 negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.1 0.4 GO:0097167 circadian regulation of translation(GO:0097167)
0.1 0.2 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1 0.7 GO:0006544 glycine metabolic process(GO:0006544)
0.1 1.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.4 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.1 0.3 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 1.0 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.1 0.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.5 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 0.7 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.1 0.7 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.6 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.1 0.1 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 5.7 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 0.4 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 0.3 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.1 0.9 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 10.0 GO:0007416 synapse assembly(GO:0007416)
0.1 0.2 GO:2000407 positive regulation of necrotic cell death(GO:0010940) T cell extravasation(GO:0072683) regulation of T cell extravasation(GO:2000407)
0.1 0.8 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.6 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.7 GO:0001711 endodermal cell fate commitment(GO:0001711)
0.1 0.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.3 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
0.1 0.2 GO:0097459 iron ion import into cell(GO:0097459) iron ion import across plasma membrane(GO:0098711)
0.1 0.3 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 0.2 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.1 0.5 GO:0043247 telomere maintenance in response to DNA damage(GO:0043247)
0.1 0.6 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.3 GO:1903273 regulation of sodium ion export(GO:1903273) positive regulation of sodium ion export(GO:1903275) regulation of sodium ion export from cell(GO:1903276) positive regulation of sodium ion export from cell(GO:1903278)
0.0 0.2 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 2.5 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.0 0.3 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.4 GO:0031053 primary miRNA processing(GO:0031053)
0.0 1.0 GO:0031297 replication fork processing(GO:0031297)
0.0 0.9 GO:0036010 protein localization to endosome(GO:0036010)
0.0 1.1 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.4 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 2.2 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.8 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.1 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.2 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.3 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 1.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.3 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.1 GO:0045073 chemokine biosynthetic process(GO:0042033) regulation of chemokine biosynthetic process(GO:0045073) regulation of circadian sleep/wake cycle, non-REM sleep(GO:0045188) chemokine metabolic process(GO:0050755) regulation of T-helper 2 cell cytokine production(GO:2000551) positive regulation of T-helper 2 cell cytokine production(GO:2000553) regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0 0.4 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.4 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 1.5 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.0 0.1 GO:0046519 sphingoid metabolic process(GO:0046519)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.3 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 1.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.2 GO:0071514 genetic imprinting(GO:0071514)
0.0 1.9 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.1 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.1 GO:0042045 epithelial fluid transport(GO:0042045)
0.0 0.5 GO:1900449 regulation of glutamate receptor signaling pathway(GO:1900449)
0.0 1.9 GO:0007601 visual perception(GO:0007601)
0.0 0.3 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.7 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.6 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 0.2 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.4 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 1.4 GO:0007405 neuroblast proliferation(GO:0007405)
0.0 0.3 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.0 0.8 GO:0043620 regulation of DNA-templated transcription in response to stress(GO:0043620)
0.0 0.0 GO:0019659 fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.0 0.4 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 0.8 GO:0032418 lysosome localization(GO:0032418)
0.0 0.3 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 0.5 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.2 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.0 0.1 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716) positive regulation of interleukin-1 beta secretion(GO:0050718)
0.0 0.4 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.5 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.0 0.1 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 1.2 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.0 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.0 0.2 GO:0031960 response to corticosteroid(GO:0031960) response to glucocorticoid(GO:0051384)
0.0 0.3 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.1 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 0.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:2000580 regulation of microtubule motor activity(GO:2000574) positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.8 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.6 3.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.6 1.7 GO:0044299 C-fiber(GO:0044299)
0.3 0.9 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.3 0.8 GO:1990075 kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075)
0.3 2.6 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.2 1.1 GO:0030870 Mre11 complex(GO:0030870)
0.2 1.1 GO:0097443 sorting endosome(GO:0097443)
0.2 2.2 GO:0044294 dendritic growth cone(GO:0044294)
0.2 0.8 GO:0001533 cornified envelope(GO:0001533)
0.2 1.0 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.2 0.9 GO:0005663 DNA replication factor C complex(GO:0005663)
0.2 0.8 GO:0030670 phagocytic vesicle membrane(GO:0030670) tertiary granule(GO:0070820)
0.2 1.1 GO:0070695 FHF complex(GO:0070695)
0.1 0.8 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.1 0.5 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.4 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.1 1.8 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 12.2 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.5 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 1.2 GO:0031209 SCAR complex(GO:0031209)
0.1 0.4 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.1 2.8 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.4 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 0.2 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 0.7 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 1.0 GO:0031045 dense core granule(GO:0031045)
0.1 1.3 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.1 0.2 GO:0098835 presynaptic endosome(GO:0098830) presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.1 0.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 1.8 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.1 0.7 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 2.2 GO:0032590 dendrite membrane(GO:0032590)
0.1 1.0 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.4 GO:0000322 storage vacuole(GO:0000322)
0.1 0.3 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.1 1.0 GO:0097225 sperm midpiece(GO:0097225)
0.1 1.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.9 GO:0005605 basal lamina(GO:0005605)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 0.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.8 GO:0042641 actomyosin(GO:0042641)
0.0 0.9 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 1.4 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 5.8 GO:0010008 endosome membrane(GO:0010008)
0.0 2.3 GO:0005811 lipid particle(GO:0005811)
0.0 0.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0097342 ripoptosome(GO:0097342)
0.0 0.2 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.6 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.8 GO:0030673 axolemma(GO:0030673)
0.0 0.9 GO:0031672 A band(GO:0031672)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.3 GO:0042588 zymogen granule(GO:0042588)
0.0 0.3 GO:0097542 ciliary tip(GO:0097542)
0.0 0.9 GO:0031201 SNARE complex(GO:0031201)
0.0 0.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.9 GO:0014704 intercalated disc(GO:0014704)
0.0 2.2 GO:0042383 sarcolemma(GO:0042383)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.0 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 1.1 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 12.3 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.8 GO:0070382 exocytic vesicle(GO:0070382)
0.0 2.6 GO:0000139 Golgi membrane(GO:0000139)
0.0 1.0 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 1.7 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.4 GO:0032040 small-subunit processome(GO:0032040)
0.0 1.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0003796 lysozyme activity(GO:0003796)
0.7 3.5 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.6 3.1 GO:0019770 IgG receptor activity(GO:0019770)
0.5 2.0 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.4 6.1 GO:0005537 mannose binding(GO:0005537)
0.4 1.6 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.4 1.9 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.4 1.8 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.3 1.0 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.3 2.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.3 4.0 GO:0031005 filamin binding(GO:0031005)
0.3 0.8 GO:0019120 hydrolase activity, acting on acid halide bonds(GO:0016824) hydrolase activity, acting on acid halide bonds, in C-halide compounds(GO:0019120) alkylhalidase activity(GO:0047651)
0.3 1.1 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.2 2.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 1.6 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.2 1.1 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.2 2.8 GO:0001846 opsonin binding(GO:0001846)
0.2 0.8 GO:0070573 metallodipeptidase activity(GO:0070573)
0.2 0.6 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.2 0.7 GO:0004966 galanin receptor activity(GO:0004966)
0.2 0.7 GO:1990269 RNA polymerase II C-terminal domain phosphoserine binding(GO:1990269)
0.2 5.1 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2 0.5 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.2 0.9 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.2 0.7 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.2 1.0 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.2 1.1 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.2 0.5 GO:0004998 transferrin receptor activity(GO:0004998)
0.2 0.9 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.2 0.6 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.3 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.4 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.1 0.4 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 3.4 GO:0001968 fibronectin binding(GO:0001968)
0.1 3.2 GO:0042287 MHC protein binding(GO:0042287)
0.1 0.6 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.5 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.1 1.0 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.3 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.6 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 0.9 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.5 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.3 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.1 0.9 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.1 0.3 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.9 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.8 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.2 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 0.7 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 5.4 GO:0019955 cytokine binding(GO:0019955)
0.1 0.4 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 0.2 GO:0019863 IgE binding(GO:0019863)
0.1 0.8 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.1 0.3 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.1 1.4 GO:0005521 lamin binding(GO:0005521)
0.1 2.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 1.3 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 0.9 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.1 1.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 1.0 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.3 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.2 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 2.6 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.9 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 2.2 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.6 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 1.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 1.1 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.2 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 1.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.4 GO:0035615 clathrin heavy chain binding(GO:0032050) clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.6 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 1.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.5 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.2 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 1.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.3 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.9 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 2.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 1.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.4 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.0 1.2 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.6 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 1.8 GO:0005178 integrin binding(GO:0005178)
0.0 1.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 2.3 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 1.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 6.6 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.3 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 0.0 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.9 GO:0005125 cytokine activity(GO:0005125)
0.0 1.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.0 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.0 0.1 GO:0008199 ferric iron binding(GO:0008199)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.5 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP
0.1 3.2 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 1.0 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 0.4 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.1 1.1 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.1 1.9 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.1 1.4 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.8 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 1.7 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.8 PID_ATM_PATHWAY ATM pathway
0.0 2.0 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.6 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 1.1 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.2 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.4 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 0.4 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.4 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 1.7 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 3.1 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID_FAS_PATHWAY FAS (CD95) signaling pathway
0.0 0.3 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 2.0 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.8 PID_CDC42_PATHWAY CDC42 signaling events
0.0 0.4 PID_ATF2_PATHWAY ATF-2 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.3 7.7 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.3 1.5 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 1.9 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 3.6 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 2.7 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.9 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 1.1 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 3.8 REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 2.1 REACTOME_DOUBLE_STRAND_BREAK_REPAIR Genes involved in Double-Strand Break Repair
0.1 2.0 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 1.7 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 0.8 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 1.8 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.6 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.4 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 1.4 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.2 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.0 1.4 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.6 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.5 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.5 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 1.0 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 2.4 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.6 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.1 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.7 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.3 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.5 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.5 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.3 REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.2 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.4 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 0.2 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.1 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.3 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.4 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.4 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.2 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.4 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits