Motif ID: E2f6

Z-value: 0.853


Transcription factors associated with E2f6:

Gene SymbolEntrez IDGene Name
E2f6 ENSMUSG00000057469.7 E2f6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
E2f6mm10_v2_chr12_+_16810940_168109780.722.1e-07Click!


Activity profile for motif E2f6.

activity profile for motif E2f6


Sorted Z-values histogram for motif E2f6

Sorted Z-values for motif E2f6



Network of associatons between targets according to the STRING database.



First level regulatory network of E2f6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_60893430 4.744 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr5_+_139543889 3.860 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr10_-_127534540 3.814 ENSMUST00000095266.2
Nxph4
neurexophilin 4
chr2_-_64097994 3.611 ENSMUST00000131615.2
Fign
fidgetin
chr16_+_44173239 3.055 ENSMUST00000119746.1
Gm608
predicted gene 608
chr16_+_44173271 3.033 ENSMUST00000088356.4
ENSMUST00000169582.1
Gm608

predicted gene 608

chr9_+_65890237 2.884 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr6_-_23248264 2.878 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr4_+_126556935 2.845 ENSMUST00000048391.8
Clspn
claspin
chr14_-_67715585 2.785 ENSMUST00000163100.1
ENSMUST00000132705.1
ENSMUST00000124045.1
Cdca2


cell division cycle associated 2


chr9_+_119402444 2.663 ENSMUST00000035093.8
ENSMUST00000165044.1
Acvr2b

activin receptor IIB

chr4_-_91372028 2.594 ENSMUST00000107110.1
ENSMUST00000008633.8
ENSMUST00000107118.1
Elavl2


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)


chrX_-_141725181 2.585 ENSMUST00000067841.7
Irs4
insulin receptor substrate 4
chr15_-_98004634 2.572 ENSMUST00000131560.1
ENSMUST00000088355.5
Col2a1

collagen, type II, alpha 1

chr2_-_117342709 2.557 ENSMUST00000173541.1
ENSMUST00000172901.1
ENSMUST00000173252.1
Rasgrp1


RAS guanyl releasing protein 1


chr15_-_98004695 2.552 ENSMUST00000023123.8
Col2a1
collagen, type II, alpha 1
chr4_+_8691303 2.492 ENSMUST00000051558.3
Chd7
chromodomain helicase DNA binding protein 7
chr4_+_8690399 2.485 ENSMUST00000127476.1
Chd7
chromodomain helicase DNA binding protein 7
chr13_+_112987802 2.334 ENSMUST00000038404.4
Ccno
cyclin O
chr4_-_91371946 2.333 ENSMUST00000176362.1
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr7_-_70360593 2.333 ENSMUST00000032768.7
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr4_+_126556994 2.328 ENSMUST00000147675.1
Clspn
claspin
chr11_+_102604370 2.281 ENSMUST00000057893.5
Fzd2
frizzled homolog 2 (Drosophila)
chr7_+_102441685 2.184 ENSMUST00000033283.9
Rrm1
ribonucleotide reductase M1
chr3_-_8667033 2.158 ENSMUST00000042412.3
Hey1
hairy/enhancer-of-split related with YRPW motif 1
chr1_-_9700209 2.106 ENSMUST00000088658.4
Mybl1
myeloblastosis oncogene-like 1
chr15_-_58135047 2.106 ENSMUST00000038194.3
Atad2
ATPase family, AAA domain containing 2
chr11_+_82388900 2.103 ENSMUST00000054245.4
ENSMUST00000092852.2
Tmem132e

transmembrane protein 132E

chr13_-_29984219 2.073 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr4_+_52439235 2.064 ENSMUST00000117280.1
ENSMUST00000102915.3
ENSMUST00000142227.1
Smc2


structural maintenance of chromosomes 2


chr13_-_103920508 2.049 ENSMUST00000053927.5
ENSMUST00000091269.4
ENSMUST00000022222.5
Erbb2ip


Erbb2 interacting protein


chr4_-_59549314 2.020 ENSMUST00000148331.2
ENSMUST00000030076.5
Ptbp3

polypyrimidine tract binding protein 3

chr7_-_81706905 2.019 ENSMUST00000026922.7
Homer2
homer homolog 2 (Drosophila)
chr13_-_111808938 1.924 ENSMUST00000109267.2
Map3k1
mitogen-activated protein kinase kinase kinase 1
chr12_-_46818749 1.918 ENSMUST00000021438.6
Nova1
neuro-oncological ventral antigen 1
chr9_+_118478851 1.890 ENSMUST00000150633.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr4_-_59549243 1.882 ENSMUST00000173699.1
ENSMUST00000173884.1
ENSMUST00000102883.4
ENSMUST00000174586.1
Ptbp3



polypyrimidine tract binding protein 3



chr17_-_35516780 1.851 ENSMUST00000160885.1
ENSMUST00000159009.1
ENSMUST00000161012.1
Tcf19


transcription factor 19


chr11_-_114795888 1.838 ENSMUST00000000206.3
Btbd17
BTB (POZ) domain containing 17
chrX_+_35888808 1.816 ENSMUST00000033419.6
Dock11
dedicator of cytokinesis 11
chr13_-_100775844 1.808 ENSMUST00000075550.3
Cenph
centromere protein H
chr19_-_58454435 1.784 ENSMUST00000169850.1
Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chrX_+_96096034 1.748 ENSMUST00000117399.1
Msn
moesin
chr14_+_31217850 1.719 ENSMUST00000090180.2
Sema3g
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
chr14_+_21500879 1.709 ENSMUST00000182964.1
Kat6b
K(lysine) acetyltransferase 6B
chr14_-_98169542 1.705 ENSMUST00000069334.7
ENSMUST00000071533.6
Dach1

dachshund 1 (Drosophila)

chr3_+_127633134 1.705 ENSMUST00000029587.7
Neurog2
neurogenin 2
chrX_-_109013389 1.703 ENSMUST00000033597.8
Hmgn5
high-mobility group nucleosome binding domain 5
chrX_-_162159717 1.701 ENSMUST00000087085.3
Nhs
Nance-Horan syndrome (human)
chr10_+_94036001 1.679 ENSMUST00000020208.4
Fgd6
FYVE, RhoGEF and PH domain containing 6
chr2_-_34372004 1.666 ENSMUST00000113132.2
ENSMUST00000040638.8
Pbx3

pre B cell leukemia homeobox 3

chr9_-_82975475 1.612 ENSMUST00000034787.5
Phip
pleckstrin homology domain interacting protein
chr2_+_18064645 1.599 ENSMUST00000114680.2
Mllt10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr11_-_88718165 1.595 ENSMUST00000107908.1
Msi2
musashi RNA-binding protein 2
chr7_-_38107490 1.570 ENSMUST00000108023.3
Ccne1
cyclin E1
chr12_+_24708241 1.570 ENSMUST00000020980.5
Rrm2
ribonucleotide reductase M2
chr4_+_128883549 1.561 ENSMUST00000035667.8
Trim62
tripartite motif-containing 62
chr18_+_35829798 1.561 ENSMUST00000060722.6
Cxxc5
CXXC finger 5
chr1_+_172481788 1.557 ENSMUST00000127052.1
Igsf9
immunoglobulin superfamily, member 9
chr1_-_82291370 1.525 ENSMUST00000069799.2
Irs1
insulin receptor substrate 1
chr7_+_13278778 1.489 ENSMUST00000098814.4
ENSMUST00000146998.1
ENSMUST00000185145.1
Lig1


ligase I, DNA, ATP-dependent


chr2_-_91931696 1.484 ENSMUST00000090602.5
Mdk
midkine
chr19_-_58454580 1.477 ENSMUST00000129100.1
ENSMUST00000123957.1
Gfra1

glial cell line derived neurotrophic factor family receptor alpha 1

chr16_+_33684538 1.469 ENSMUST00000126532.1
Heg1
HEG homolog 1 (zebrafish)
chr8_+_26977336 1.442 ENSMUST00000154256.1
ENSMUST00000127097.1
Zfp703

zinc finger protein 703

chr11_+_49203465 1.438 ENSMUST00000150284.1
ENSMUST00000109197.1
ENSMUST00000151228.1
Zfp62


zinc finger protein 62


chr2_+_18064564 1.431 ENSMUST00000114671.1
Mllt10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr1_-_13372434 1.427 ENSMUST00000081713.4
Ncoa2
nuclear receptor coactivator 2
chr18_+_10725530 1.427 ENSMUST00000052838.4
Mib1
mindbomb homolog 1 (Drosophila)
chr11_-_74723829 1.426 ENSMUST00000102520.2
Pafah1b1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr11_+_29172890 1.424 ENSMUST00000102856.2
ENSMUST00000020755.5
Smek2

SMEK homolog 2, suppressor of mek1 (Dictyostelium)

chr18_+_10725651 1.416 ENSMUST00000165555.1
Mib1
mindbomb homolog 1 (Drosophila)
chr12_+_24708984 1.415 ENSMUST00000154588.1
Rrm2
ribonucleotide reductase M2
chr14_+_122475397 1.412 ENSMUST00000075888.5
Zic2
zinc finger protein of the cerebellum 2
chr12_+_16810940 1.409 ENSMUST00000020908.7
E2f6
E2F transcription factor 6
chr12_+_16894894 1.407 ENSMUST00000020904.6
Rock2
Rho-associated coiled-coil containing protein kinase 2
chr13_+_48261427 1.401 ENSMUST00000021810.1
Id4
inhibitor of DNA binding 4
chr5_+_115845229 1.386 ENSMUST00000137952.1
ENSMUST00000148245.1
Cit

citron

chr6_-_38875923 1.377 ENSMUST00000162359.1
Hipk2
homeodomain interacting protein kinase 2
chr6_-_38875965 1.370 ENSMUST00000160360.1
Hipk2
homeodomain interacting protein kinase 2
chr4_+_11191726 1.365 ENSMUST00000029866.9
ENSMUST00000108324.3
Ccne2

cyclin E2

chr1_-_75219245 1.365 ENSMUST00000079464.6
Tuba4a
tubulin, alpha 4A
chr10_+_42761483 1.362 ENSMUST00000019937.4
Sec63
SEC63-like (S. cerevisiae)
chr4_+_116877376 1.361 ENSMUST00000044823.3
Zswim5
zinc finger SWIM-type containing 5
chr11_-_116335384 1.361 ENSMUST00000036215.7
Foxj1
forkhead box J1
chr8_+_106935720 1.355 ENSMUST00000047425.3
Sntb2
syntrophin, basic 2
chr15_+_39198244 1.341 ENSMUST00000082054.5
ENSMUST00000042917.9
Rims2

regulating synaptic membrane exocytosis 2

chr13_-_89742244 1.338 ENSMUST00000109543.2
ENSMUST00000159337.1
ENSMUST00000159910.1
ENSMUST00000109544.2
Vcan



versican



chrX_-_12080545 1.338 ENSMUST00000115513.2
ENSMUST00000115512.2
ENSMUST00000065143.7
ENSMUST00000124033.1
Bcor



BCL6 interacting corepressor



chr19_+_53529100 1.335 ENSMUST00000038287.6
Dusp5
dual specificity phosphatase 5
chr3_-_142881942 1.325 ENSMUST00000043812.8
Pkn2
protein kinase N2
chr2_-_91931675 1.322 ENSMUST00000111309.1
Mdk
midkine
chr5_-_88675190 1.320 ENSMUST00000133532.1
ENSMUST00000150438.1
Grsf1

G-rich RNA sequence binding factor 1

chr17_+_56303321 1.315 ENSMUST00000001258.8
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr2_+_164562579 1.309 ENSMUST00000017867.3
ENSMUST00000109344.2
ENSMUST00000109345.2
Wfdc2


WAP four-disulfide core domain 2


chr13_-_78197815 1.308 ENSMUST00000127137.2
Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr7_-_49636847 1.305 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chr13_+_15463837 1.305 ENSMUST00000110510.3
Gli3
GLI-Kruppel family member GLI3
chr12_-_98901478 1.304 ENSMUST00000065716.6
Eml5
echinoderm microtubule associated protein like 5
chr13_-_107022027 1.302 ENSMUST00000117539.1
ENSMUST00000122233.1
ENSMUST00000022204.9
ENSMUST00000159772.1
Kif2a



kinesin family member 2A



chr11_+_49203285 1.301 ENSMUST00000109198.1
ENSMUST00000137061.2
Zfp62

zinc finger protein 62

chr8_+_62951195 1.294 ENSMUST00000118003.1
Spock3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3
chr8_+_34807287 1.294 ENSMUST00000033930.4
Dusp4
dual specificity phosphatase 4
chr13_-_40733768 1.281 ENSMUST00000110193.2
Tfap2a
transcription factor AP-2, alpha
chr6_+_113531675 1.279 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2

Fanconi anemia, complementation group D2

chr11_+_80300866 1.260 ENSMUST00000017836.7
Rhbdl3
rhomboid, veinlet-like 3 (Drosophila)
chr16_+_20517076 1.260 ENSMUST00000171774.1
Dvl3
dishevelled 3, dsh homolog (Drosophila)
chr16_+_58408443 1.255 ENSMUST00000046663.7
Dcbld2
discoidin, CUB and LCCL domain containing 2
chr13_-_89742490 1.254 ENSMUST00000109546.2
Vcan
versican
chr2_+_49451486 1.251 ENSMUST00000092123.4
Epc2
enhancer of polycomb homolog 2 (Drosophila)
chr12_+_69168808 1.251 ENSMUST00000110621.1
Lrr1
leucine rich repeat protein 1
chr15_+_55557399 1.228 ENSMUST00000022998.7
Mtbp
Mdm2, transformed 3T3 cell double minute p53 binding protein
chr19_-_58455161 1.224 ENSMUST00000135730.1
ENSMUST00000152507.1
Gfra1

glial cell line derived neurotrophic factor family receptor alpha 1

chr19_-_41743665 1.217 ENSMUST00000025993.3
Slit1
slit homolog 1 (Drosophila)
chr2_-_102186322 1.216 ENSMUST00000111222.1
ENSMUST00000058790.5
Ldlrad3

low density lipoprotein receptor class A domain containing 3

chr6_+_134929089 1.213 ENSMUST00000183867.1
ENSMUST00000184991.1
ENSMUST00000183905.1
RP23-45G16.5


RP23-45G16.5


chr2_-_91931774 1.209 ENSMUST00000069423.6
Mdk
midkine
chr12_+_76533540 1.197 ENSMUST00000075249.4
Plekhg3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chrX_-_23365044 1.189 ENSMUST00000115313.1
Klhl13
kelch-like 13
chr2_-_153241402 1.189 ENSMUST00000056924.7
Plagl2
pleiomorphic adenoma gene-like 2
chr9_+_72274860 1.169 ENSMUST00000184036.1
ENSMUST00000184517.1
ENSMUST00000098576.3
Zfp280d


zinc finger protein 280D


chr9_+_72274966 1.156 ENSMUST00000183410.1
Zfp280d
zinc finger protein 280D
chr6_+_134929118 1.156 ENSMUST00000185152.1
ENSMUST00000184504.1
RP23-45G16.5

RP23-45G16.5

chr9_+_58134535 1.142 ENSMUST00000128378.1
ENSMUST00000150820.1
ENSMUST00000167479.1
ENSMUST00000134450.1
Stra6



stimulated by retinoic acid gene 6



chr2_+_119325784 1.134 ENSMUST00000102517.3
Dll4
delta-like 4 (Drosophila)
chr10_-_5922385 1.130 ENSMUST00000131996.1
ENSMUST00000064225.7
Rgs17

regulator of G-protein signaling 17

chr9_-_63146980 1.117 ENSMUST00000055281.7
ENSMUST00000119146.1
Skor1

SKI family transcriptional corepressor 1

chr11_-_88718078 1.115 ENSMUST00000092794.5
Msi2
musashi RNA-binding protein 2
chr15_+_55557575 1.107 ENSMUST00000170046.1
Mtbp
Mdm2, transformed 3T3 cell double minute p53 binding protein
chr9_-_106789130 1.105 ENSMUST00000046502.5
Rad54l2
RAD54 like 2 (S. cerevisiae)
chr1_-_52233211 1.102 ENSMUST00000114513.2
ENSMUST00000114510.1
Gls

glutaminase

chr15_-_85581809 1.100 ENSMUST00000023015.7
Wnt7b
wingless-related MMTV integration site 7B
chr9_-_100546053 1.100 ENSMUST00000116522.1
Nck1
non-catalytic region of tyrosine kinase adaptor protein 1
chr9_+_70679016 1.092 ENSMUST00000144537.1
Adam10
a disintegrin and metallopeptidase domain 10
chr2_-_125625065 1.087 ENSMUST00000089776.2
Cep152
centrosomal protein 152
chr2_+_84839395 1.086 ENSMUST00000146816.1
ENSMUST00000028469.7
Slc43a1

solute carrier family 43, member 1

chr4_-_133753611 1.085 ENSMUST00000145664.2
ENSMUST00000105897.3
Arid1a

AT rich interactive domain 1A (SWI-like)

chr12_+_110279228 1.081 ENSMUST00000097228.4
Dio3
deiodinase, iodothyronine type III
chr4_+_86748526 1.078 ENSMUST00000082026.7
ENSMUST00000045512.8
Dennd4c

DENN/MADD domain containing 4C

chr2_-_172940299 1.078 ENSMUST00000009143.7
Bmp7
bone morphogenetic protein 7
chr17_+_56303396 1.074 ENSMUST00000113038.1
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr14_-_55092277 1.063 ENSMUST00000036328.8
Zfhx2
zinc finger homeobox 2
chr11_-_88718223 1.061 ENSMUST00000107909.1
Msi2
musashi RNA-binding protein 2
chr19_+_7268296 1.055 ENSMUST00000066646.4
Rcor2
REST corepressor 2
chr8_+_116504973 1.054 ENSMUST00000078170.5
Dynlrb2
dynein light chain roadblock-type 2
chr10_+_108162358 1.054 ENSMUST00000070663.5
Ppp1r12a
protein phosphatase 1, regulatory (inhibitor) subunit 12A
chr10_-_117376922 1.050 ENSMUST00000177145.1
ENSMUST00000176670.1
Cpsf6

cleavage and polyadenylation specific factor 6

chr1_-_37865040 1.049 ENSMUST00000041815.8
Tsga10
testis specific 10
chr15_-_84855093 1.047 ENSMUST00000016768.5
Phf21b
PHD finger protein 21B
chr5_+_125003440 1.038 ENSMUST00000036109.3
Fam101a
family with sequence similarity 101, member A
chr2_-_157204483 1.020 ENSMUST00000029170.7
Rbl1
retinoblastoma-like 1 (p107)
chr5_-_65697856 1.016 ENSMUST00000031104.6
Pds5a
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr7_+_100227638 1.004 ENSMUST00000054436.8
Pgm2l1
phosphoglucomutase 2-like 1
chr14_-_47276790 1.003 ENSMUST00000111792.1
ENSMUST00000111791.1
ENSMUST00000111790.1
Wdhd1


WD repeat and HMG-box DNA binding protein 1


chr4_-_153482768 0.999 ENSMUST00000105646.2
Ajap1
adherens junction associated protein 1
chr3_+_14533817 0.985 ENSMUST00000169079.1
ENSMUST00000091325.3
Lrrcc1

leucine rich repeat and coiled-coil domain containing 1

chr1_+_172482199 0.980 ENSMUST00000135267.1
ENSMUST00000052629.6
ENSMUST00000111235.2
Igsf9


immunoglobulin superfamily, member 9


chr12_-_102878406 0.975 ENSMUST00000045652.6
Btbd7
BTB (POZ) domain containing 7
chr5_+_81021202 0.974 ENSMUST00000117253.1
ENSMUST00000120128.1
Lphn3

latrophilin 3

chr3_+_14533867 0.973 ENSMUST00000163660.1
Lrrcc1
leucine rich repeat and coiled-coil domain containing 1
chr2_+_103566304 0.972 ENSMUST00000076212.3
Abtb2
ankyrin repeat and BTB (POZ) domain containing 2
chr13_-_78199757 0.966 ENSMUST00000091458.6
Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr7_-_133123312 0.966 ENSMUST00000124096.1
ENSMUST00000171022.1
ENSMUST00000163601.1
ENSMUST00000165534.1
ENSMUST00000033269.8
Fgfr2
Ctbp2



fibroblast growth factor receptor 2
C-terminal binding protein 2



chr4_-_41697040 0.965 ENSMUST00000102962.3
ENSMUST00000084701.5
Cntfr

ciliary neurotrophic factor receptor

chr19_+_56548254 0.962 ENSMUST00000071423.5
Nhlrc2
NHL repeat containing 2
chr11_+_119022962 0.957 ENSMUST00000026662.7
Cbx2
chromobox 2
chr15_-_94404258 0.953 ENSMUST00000035342.4
ENSMUST00000155907.1
Adamts20

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20

chr11_+_43528759 0.952 ENSMUST00000050574.6
Ccnjl
cyclin J-like
chr6_-_148946146 0.950 ENSMUST00000132696.1
Fam60a
family with sequence similarity 60, member A
chr3_+_156562141 0.948 ENSMUST00000175773.1
Negr1
neuronal growth regulator 1
chr14_+_67716095 0.944 ENSMUST00000078053.6
ENSMUST00000145542.1
ENSMUST00000125212.1
Kctd9


potassium channel tetramerisation domain containing 9


chr14_+_31019125 0.942 ENSMUST00000112095.1
ENSMUST00000112098.3
ENSMUST00000112106.1
ENSMUST00000146325.1
Pbrm1



polybromo 1



chr4_-_41695442 0.941 ENSMUST00000102961.3
ENSMUST00000064443.6
Cntfr

ciliary neurotrophic factor receptor

chr4_+_95967205 0.934 ENSMUST00000030306.7
Hook1
hook homolog 1 (Drosophila)
chr15_-_10714612 0.930 ENSMUST00000169385.1
Rai14
retinoic acid induced 14
chr1_-_135688094 0.923 ENSMUST00000112103.1
Nav1
neuron navigator 1
chr18_-_84589491 0.918 ENSMUST00000125763.1
Zfp407
zinc finger protein 407
chr4_-_135272798 0.918 ENSMUST00000037099.8
Clic4
chloride intracellular channel 4 (mitochondrial)
chr14_+_67716262 0.916 ENSMUST00000150768.1
Kctd9
potassium channel tetramerisation domain containing 9
chr7_-_118855984 0.911 ENSMUST00000116280.2
ENSMUST00000106550.3
ENSMUST00000063607.5
Knop1


lysine rich nucleolar protein 1


chr3_+_105452326 0.908 ENSMUST00000098761.3
Kcnd3
potassium voltage-gated channel, Shal-related family, member 3
chr2_+_92184106 0.908 ENSMUST00000111294.1
ENSMUST00000111293.2
ENSMUST00000162146.1
ENSMUST00000111292.1
ENSMUST00000162497.1
Phf21a




PHD finger protein 21A




chr17_-_24960620 0.905 ENSMUST00000024981.7
Hn1l
hematological and neurological expressed 1-like
chr6_-_47594967 0.903 ENSMUST00000081721.6
ENSMUST00000114618.1
ENSMUST00000114616.1
Ezh2


enhancer of zeste homolog 2 (Drosophila)


chr6_+_42350000 0.901 ENSMUST00000164375.1
Zyx
zyxin
chr8_+_104831572 0.898 ENSMUST00000059449.6
Ces2b
carboxyesterase 2B
chr11_+_98907801 0.895 ENSMUST00000092706.6
Cdc6
cell division cycle 6
chr11_-_100939357 0.892 ENSMUST00000092671.5
ENSMUST00000103114.1
Stat3

signal transducer and activator of transcription 3

chr14_+_31019159 0.892 ENSMUST00000112094.1
ENSMUST00000144009.1
Pbrm1

polybromo 1

chr11_-_107131922 0.890 ENSMUST00000057892.8
Bptf
bromodomain PHD finger transcription factor
chr11_-_77078404 0.889 ENSMUST00000102494.1
Ccdc55
coiled-coil domain containing 55
chr11_-_100939457 0.885 ENSMUST00000138438.1
Stat3
signal transducer and activator of transcription 3
chr11_+_21239279 0.882 ENSMUST00000006221.7
ENSMUST00000109578.1
Vps54

vacuolar protein sorting 54 (yeast)

chr9_-_36726374 0.880 ENSMUST00000172702.2
ENSMUST00000172742.1
ENSMUST00000034625.5
Chek1


checkpoint kinase 1


chr2_+_154436437 0.875 ENSMUST00000109725.1
ENSMUST00000099178.3
ENSMUST00000045270.8
ENSMUST00000109724.1
Cbfa2t2



core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human)



chr11_-_100939540 0.873 ENSMUST00000127638.1
Stat3
signal transducer and activator of transcription 3
chr5_+_47984571 0.873 ENSMUST00000174313.1
Slit2
slit homolog 2 (Drosophila)
chr3_+_156561792 0.867 ENSMUST00000074015.4
Negr1
neuronal growth regulator 1
chr16_-_18811615 0.864 ENSMUST00000096990.3
Cdc45
cell division cycle 45
chr13_-_21750505 0.864 ENSMUST00000102983.1
Hist1h4k
histone cluster 1, H4k

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
1.3 4.0 GO:0030421 defecation(GO:0030421)
0.8 2.5 GO:0072554 blood vessel lumenization(GO:0072554)
0.8 3.0 GO:0003360 brainstem development(GO:0003360)
0.7 0.7 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.7 2.7 GO:1902724 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.6 1.3 GO:0003404 optic vesicle morphogenesis(GO:0003404)
0.6 3.2 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.6 1.9 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.6 1.8 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.6 2.9 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.6 0.6 GO:0060769 positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769)
0.6 1.7 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.6 2.2 GO:0015888 thiamine transport(GO:0015888)
0.6 1.1 GO:0072053 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.5 6.5 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.5 2.2 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.5 5.3 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.5 2.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.5 5.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.5 1.0 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.5 0.5 GO:0061113 pancreas morphogenesis(GO:0061113)
0.5 1.5 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.5 1.4 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.5 3.4 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.5 1.4 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.5 2.3 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.5 2.3 GO:0007223 muscular septum morphogenesis(GO:0003150) Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.5 1.4 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.4 1.8 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.4 1.3 GO:0060364 frontal suture morphogenesis(GO:0060364)
0.4 0.9 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.4 0.8 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.4 2.5 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.4 2.9 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.4 2.7 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.4 1.1 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.4 1.4 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.4 1.4 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.4 1.1 GO:0099547 regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254)
0.3 1.4 GO:0033085 negative regulation of T cell differentiation in thymus(GO:0033085) negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.3 1.7 GO:0061511 centriole elongation(GO:0061511)
0.3 3.0 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.3 5.9 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.3 0.7 GO:0072180 mesonephric duct development(GO:0072177) mesonephric duct morphogenesis(GO:0072180)
0.3 1.0 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.3 1.0 GO:0035604 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) coronal suture morphogenesis(GO:0060365) squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529)
0.3 0.9 GO:1904978 regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
0.3 2.2 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.3 1.5 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.3 5.5 GO:0051383 kinetochore organization(GO:0051383)
0.3 1.7 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.3 0.9 GO:0045004 DNA replication proofreading(GO:0045004)
0.3 1.4 GO:0051661 maintenance of centrosome location(GO:0051661)
0.3 1.1 GO:0010288 response to lead ion(GO:0010288)
0.3 1.3 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.3 3.9 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.3 1.3 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.3 0.8 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.3 0.8 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.3 1.3 GO:0006543 glutamine catabolic process(GO:0006543)
0.3 1.0 GO:0070829 heterochromatin maintenance(GO:0070829)
0.2 1.0 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.2 1.0 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.2 3.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.2 0.7 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.2 1.2 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.2 1.1 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) alveolar primary septum development(GO:0061143)
0.2 0.2 GO:1901563 response to camptothecin(GO:1901563)
0.2 1.8 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.2 3.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.2 4.6 GO:0007530 sex determination(GO:0007530)
0.2 0.7 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.2 0.9 GO:1904953 Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904953)
0.2 1.9 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2 0.4 GO:0061144 alveolar secondary septum development(GO:0061144)
0.2 0.4 GO:0051660 establishment of centrosome localization(GO:0051660)
0.2 1.4 GO:1904017 response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.2 1.0 GO:0061038 uterus morphogenesis(GO:0061038)
0.2 1.4 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.2 1.6 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.2 0.8 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.2 1.6 GO:0015074 DNA integration(GO:0015074)
0.2 0.6 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.2 0.6 GO:0036292 DNA rewinding(GO:0036292)
0.2 2.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.2 0.6 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.2 1.3 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.2 1.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.2 0.7 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.2 0.9 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.2 1.3 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.2 1.1 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.2 1.4 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.2 0.7 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.2 0.9 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.2 0.5 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.2 0.5 GO:0019441 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218) kynurenine metabolic process(GO:0070189)
0.2 0.7 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.2 0.5 GO:0021502 neural fold elevation formation(GO:0021502)
0.2 1.9 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151)
0.2 0.7 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.2 1.0 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.2 0.5 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
0.2 0.2 GO:0051572 negative regulation of histone H3-K4 methylation(GO:0051572)
0.2 0.5 GO:0030210 heparin biosynthetic process(GO:0030210) Tie signaling pathway(GO:0048014)
0.2 0.6 GO:0035021 amygdala development(GO:0021764) negative regulation of Rac protein signal transduction(GO:0035021)
0.2 1.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.2 0.5 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.2 1.1 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
0.2 0.6 GO:2001045 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.2 0.6 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.2 0.8 GO:0071896 protein localization to adherens junction(GO:0071896)
0.2 0.5 GO:0010958 regulation of amino acid import(GO:0010958)
0.1 0.4 GO:0019085 early viral transcription(GO:0019085)
0.1 0.4 GO:1904690 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.1 1.5 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 0.4 GO:0021759 globus pallidus development(GO:0021759)
0.1 4.6 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 0.9 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.4 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 1.4 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 2.0 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.1 0.4 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162)
0.1 1.1 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.1 2.0 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 1.0 GO:1904948 midbrain dopaminergic neuron differentiation(GO:1904948)
0.1 0.4 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.1 1.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.7 GO:1902741 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.1 0.4 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.1 0.5 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.1 0.4 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 0.6 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.5 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 0.2 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.1 0.4 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.1 0.7 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.1 0.5 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.4 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.1 1.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 1.5 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 0.7 GO:0071372 response to follicle-stimulating hormone(GO:0032354) cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 1.5 GO:0034377 plasma lipoprotein particle assembly(GO:0034377)
0.1 0.5 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.5 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 1.5 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 0.3 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.1 0.4 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.7 GO:1903317 regulation of protein processing(GO:0070613) regulation of protein maturation(GO:1903317)
0.1 0.9 GO:0060736 prostate gland growth(GO:0060736)
0.1 0.9 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.7 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.1 0.9 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.1 0.5 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 0.2 GO:0072179 nephric duct formation(GO:0072179)
0.1 0.2 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.8 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.1 1.3 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.1 0.7 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.6 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.5 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 1.5 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.1 0.3 GO:0060558 negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137) regulation of calcidiol 1-monooxygenase activity(GO:0060558)
0.1 0.2 GO:0007413 axonal fasciculation(GO:0007413)
0.1 0.4 GO:0045654 thrombopoietin-mediated signaling pathway(GO:0038163) positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 1.5 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.1 0.2 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 0.4 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 0.8 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.1 0.6 GO:0016584 nucleosome positioning(GO:0016584)
0.1 1.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.4 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.6 GO:2000323 response to redox state(GO:0051775) negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1 2.9 GO:0007129 synapsis(GO:0007129)
0.1 1.4 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 0.3 GO:0061743 motor learning(GO:0061743)
0.1 1.2 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 1.1 GO:1990403 embryonic brain development(GO:1990403)
0.1 0.3 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.1 1.0 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 0.9 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.9 GO:0032682 negative regulation of chemokine production(GO:0032682)
0.1 3.0 GO:0001947 heart looping(GO:0001947)
0.1 0.8 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 0.2 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.1 0.8 GO:0001675 acrosome assembly(GO:0001675)
0.1 0.5 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.7 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1 0.5 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 0.4 GO:1990504 dense core granule exocytosis(GO:1990504)
0.1 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.5 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.6 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.1 0.6 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.8 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.5 GO:0034351 negative regulation of glial cell apoptotic process(GO:0034351)
0.1 1.0 GO:0097237 cellular response to toxic substance(GO:0097237)
0.1 1.5 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.1 0.7 GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307)
0.1 2.2 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)
0.1 0.4 GO:0072697 protein localization to cell cortex(GO:0072697)
0.1 1.8 GO:0046596 regulation of viral entry into host cell(GO:0046596)
0.1 0.6 GO:0070423 response to peptidoglycan(GO:0032494) nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.1 0.4 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 0.9 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.1 0.2 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 0.7 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.5 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 0.3 GO:0098543 detection of bacterium(GO:0016045) detection of other organism(GO:0098543)
0.1 0.2 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 2.3 GO:0006284 base-excision repair(GO:0006284)
0.1 0.1 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.1 0.7 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.1 0.4 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1 2.4 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 0.3 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.3 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.4 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 0.8 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.4 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 0.3 GO:0007320 insemination(GO:0007320)
0.1 0.2 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.4 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.1 0.8 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 0.3 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.1 0.2 GO:1905245 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) negative regulation of metalloendopeptidase activity(GO:1904684) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.1 2.3 GO:0006378 mRNA polyadenylation(GO:0006378)
0.1 0.1 GO:0002842 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) positive regulation of T cell mediated immune response to tumor cell(GO:0002842)
0.1 0.1 GO:0072103 renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.1 0.7 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.9 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 1.2 GO:0030517 negative regulation of axon extension(GO:0030517)
0.0 0.6 GO:0099515 actin filament-based transport(GO:0099515)
0.0 0.6 GO:0051984 positive regulation of chromosome segregation(GO:0051984)
0.0 0.3 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.1 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.2 GO:0060178 regulation of exocyst localization(GO:0060178)
0.0 1.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.2 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.0 0.1 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.5 GO:0001569 patterning of blood vessels(GO:0001569)
0.0 0.1 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.0 0.5 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0 0.6 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0071435 potassium ion export(GO:0071435)
0.0 0.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.5 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.3 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.3 GO:0008343 adult feeding behavior(GO:0008343)
0.0 1.2 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.4 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.0 0.8 GO:0032288 myelin assembly(GO:0032288)
0.0 0.3 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.4 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.2 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 1.3 GO:1902850 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.0 0.2 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.0 0.2 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.0 0.8 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.4 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.3 GO:0010225 response to UV-C(GO:0010225)
0.0 0.3 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.2 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.2 GO:0002551 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753)
0.0 0.0 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.0 0.3 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.3 GO:1904152 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) regulation of retrograde protein transport, ER to cytosol(GO:1904152) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.3 GO:1902913 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.0 0.7 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.5 GO:0050892 intestinal absorption(GO:0050892)
0.0 0.0 GO:0019046 viral latency(GO:0019042) release from viral latency(GO:0019046)
0.0 0.1 GO:0055009 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009) left lung development(GO:0060459) cardiac neural crest cell development involved in outflow tract morphogenesis(GO:0061309)
0.0 0.9 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.3 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.0 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.2 GO:1902510 regulation of apoptotic DNA fragmentation(GO:1902510)
0.0 0.2 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.6 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.8 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.2 GO:0032060 bleb assembly(GO:0032060)
0.0 1.8 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.1 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 0.8 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.2 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 0.6 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.3 GO:0001967 suckling behavior(GO:0001967)
0.0 0.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.1 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.4 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.0 GO:1900368 regulation of RNA interference(GO:1900368)
0.0 0.3 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.7 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.9 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.3 GO:0042711 maternal behavior(GO:0042711)
0.0 0.4 GO:0051764 actin crosslink formation(GO:0051764)
0.0 1.2 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.1 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.0 0.1 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0006014 D-ribose metabolic process(GO:0006014)
0.0 0.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 2.4 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 0.1 GO:0033280 response to vitamin D(GO:0033280)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.5 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.3 GO:0001916 positive regulation of T cell mediated cytotoxicity(GO:0001916)
0.0 0.2 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.6 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.2 GO:0050691 regulation of defense response to virus by host(GO:0050691)
0.0 0.2 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 1.0 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.4 GO:0006006 glucose metabolic process(GO:0006006)
0.0 0.2 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.3 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.3 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.0 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.1 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.0 0.1 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 1.8 GO:0008033 tRNA processing(GO:0008033)
0.0 0.0 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.0 0.1 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.5 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.0 0.0 GO:1990839 response to endothelin(GO:1990839)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 1.8 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731)
0.0 0.1 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.1 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.2 GO:0098534 centriole replication(GO:0007099) centriole assembly(GO:0098534)
0.0 0.6 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.0 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.0 0.4 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.8 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.2 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.0 0.5 GO:0048747 muscle fiber development(GO:0048747)
0.0 0.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.0 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.0 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.0 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.3 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.0 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.0 GO:0009414 response to water deprivation(GO:0009414)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.9 2.7 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.5 1.5 GO:0005899 insulin receptor complex(GO:0005899)
0.5 1.4 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.4 5.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.4 1.6 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.4 1.1 GO:0031251 PAN complex(GO:0031251)
0.3 1.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.3 0.9 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.3 1.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.3 1.7 GO:0098536 deuterosome(GO:0098536)
0.3 2.5 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.3 1.1 GO:1902737 viral replication complex(GO:0019034) dendritic filopodium(GO:1902737)
0.3 1.1 GO:0090537 CERF complex(GO:0090537)
0.2 1.0 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.2 1.4 GO:0000235 astral microtubule(GO:0000235)
0.2 1.8 GO:0042382 paraspeckles(GO:0042382)
0.2 1.5 GO:0070695 FHF complex(GO:0070695)
0.2 0.7 GO:0034457 Mpp10 complex(GO:0034457)
0.2 1.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2 0.6 GO:0005726 perichromatin fibrils(GO:0005726)
0.2 1.9 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 1.0 GO:0033553 rDNA heterochromatin(GO:0033553)
0.2 1.9 GO:0000796 condensin complex(GO:0000796)
0.2 0.6 GO:0018444 translation release factor complex(GO:0018444)
0.2 2.0 GO:0032426 stereocilium tip(GO:0032426)
0.2 1.4 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.2 0.9 GO:0032437 cuticular plate(GO:0032437)
0.2 0.8 GO:0030891 VCB complex(GO:0030891)
0.2 0.8 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.9 GO:0000938 GARP complex(GO:0000938)
0.1 0.4 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.1 2.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 0.4 GO:0035061 interchromatin granule(GO:0035061)
0.1 1.3 GO:1990909 Wnt signalosome(GO:1990909)
0.1 1.4 GO:0001739 sex chromatin(GO:0001739)
0.1 0.5 GO:0043293 apoptosome(GO:0043293)
0.1 0.6 GO:0016600 flotillin complex(GO:0016600)
0.1 0.7 GO:0001940 male pronucleus(GO:0001940)
0.1 0.6 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 1.1 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.4 GO:0097543 ciliary inversin compartment(GO:0097543)
0.1 1.7 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.9 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 3.9 GO:0060077 inhibitory synapse(GO:0060077)
0.1 5.8 GO:0000791 euchromatin(GO:0000791)
0.1 0.3 GO:1990423 Dsl1p complex(GO:0070939) RZZ complex(GO:1990423)
0.1 0.8 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 0.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.8 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.7 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 1.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 1.9 GO:0097470 ribbon synapse(GO:0097470)
0.1 0.9 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 1.7 GO:0071564 npBAF complex(GO:0071564)
0.1 0.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 1.9 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.6 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.6 GO:0031010 ISWI-type complex(GO:0031010)
0.1 0.3 GO:0000801 central element(GO:0000801)
0.1 1.8 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.5 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.7 GO:0031415 NatA complex(GO:0031415)
0.1 3.5 GO:0016592 mediator complex(GO:0016592)
0.1 1.4 GO:0090544 BAF-type complex(GO:0090544)
0.1 1.9 GO:0043596 nuclear replication fork(GO:0043596)
0.1 0.3 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.3 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 0.7 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.6 GO:0097413 Lewy body(GO:0097413)
0.1 0.7 GO:0045120 pronucleus(GO:0045120)
0.1 0.6 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.1 1.0 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 0.9 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.1 0.6 GO:0005883 neurofilament(GO:0005883)
0.1 0.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.5 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.1 1.0 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 5.5 GO:0016363 nuclear matrix(GO:0016363)
0.1 0.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1 8.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 4.2 GO:0005844 polysome(GO:0005844)
0.1 0.3 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 2.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.4 GO:0005916 fascia adherens(GO:0005916)
0.1 0.6 GO:0030057 desmosome(GO:0030057)
0.1 0.2 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 0.3 GO:0044301 climbing fiber(GO:0044301)
0.1 0.2 GO:0001740 Barr body(GO:0001740)
0.1 0.2 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.5 GO:0090543 Flemming body(GO:0090543)
0.0 1.0 GO:0000145 exocyst(GO:0000145)
0.0 1.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.5 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.0 0.4 GO:0010369 chromocenter(GO:0010369)
0.0 0.9 GO:0005657 replication fork(GO:0005657)
0.0 1.8 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.2 GO:0097255 R2TP complex(GO:0097255)
0.0 1.8 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 2.0 GO:0005871 kinesin complex(GO:0005871)
0.0 0.8 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.9 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 1.5 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.8 GO:0030496 midbody(GO:0030496)
0.0 1.0 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 0.2 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 1.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.6 GO:0051233 spindle midzone(GO:0051233)
0.0 0.9 GO:0043194 axon initial segment(GO:0043194)
0.0 0.4 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 3.2 GO:0000776 kinetochore(GO:0000776)
0.0 1.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.7 GO:0044815 nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.0 0.1 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.2 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.7 GO:0030904 retromer complex(GO:0030904)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 2.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.8 GO:0005882 intermediate filament(GO:0005882)
0.0 3.2 GO:0005813 centrosome(GO:0005813)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 1.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 2.3 GO:0005874 microtubule(GO:0005874)
0.0 0.7 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.6 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0097542 ciliary tip(GO:0097542)
0.0 0.6 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.2 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.5 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 2.3 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.9 GO:0000793 condensed chromosome(GO:0000793)
0.0 0.8 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.2 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.2 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:1904115 axon cytoplasm(GO:1904115)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.2 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
1.0 5.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.9 5.3 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.7 2.2 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.7 2.2 GO:0035939 microsatellite binding(GO:0035939)
0.6 2.4 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.6 2.3 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.5 1.9 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.4 2.7 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.4 1.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.4 1.5 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.4 0.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.4 1.8 GO:0043515 kinetochore binding(GO:0043515)
0.4 2.9 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.4 1.1 GO:0070615 nucleosome-dependent ATPase activity(GO:0070615)
0.3 2.7 GO:0046790 virion binding(GO:0046790)
0.3 2.7 GO:0034711 inhibin binding(GO:0034711)
0.3 2.7 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.3 0.9 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.3 2.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.3 2.0 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.3 1.4 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.3 1.1 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.3 2.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.3 0.8 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.3 1.3 GO:0005113 patched binding(GO:0005113)
0.2 0.7 GO:0008384 IkappaB kinase activity(GO:0008384)
0.2 1.5 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.2 2.7 GO:0019992 diacylglycerol binding(GO:0019992)
0.2 1.5 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2 1.4 GO:0033142 progesterone receptor binding(GO:0033142)
0.2 1.8 GO:0048495 Roundabout binding(GO:0048495)
0.2 0.7 GO:0004994 somatostatin receptor activity(GO:0004994)
0.2 1.1 GO:0004359 glutaminase activity(GO:0004359)
0.2 1.7 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.2 1.7 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2 1.4 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.2 6.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 5.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 0.9 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.2 1.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.2 1.3 GO:0034056 estrogen response element binding(GO:0034056)
0.2 1.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.2 0.9 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.2 0.5 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.2 2.3 GO:0001972 retinoic acid binding(GO:0001972)
0.2 2.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 0.5 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.2 1.4 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.2 0.5 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.2 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.2 4.0 GO:0008266 poly(U) RNA binding(GO:0008266)
0.2 0.7 GO:0036033 mediator complex binding(GO:0036033)
0.2 0.5 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.2 0.5 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.2 3.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.2 1.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2 2.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.4 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.1 0.9 GO:0050693 LBD domain binding(GO:0050693)
0.1 1.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 2.9 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 0.6 GO:0032027 myosin light chain binding(GO:0032027)
0.1 0.5 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.7 GO:0097001 ceramide binding(GO:0097001)
0.1 1.1 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.5 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.1 0.6 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.6 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 3.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.7 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 0.4 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.7 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 0.7 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.3 GO:0043199 sulfate binding(GO:0043199)
0.1 2.6 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 1.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.6 GO:0071253 connexin binding(GO:0071253)
0.1 0.5 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.7 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 0.5 GO:1990188 euchromatin binding(GO:1990188)
0.1 0.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.8 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.8 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 1.2 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 1.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.4 GO:0035497 cAMP response element binding(GO:0035497)
0.1 1.1 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 0.9 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 0.5 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 4.9 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 1.1 GO:0043495 protein anchor(GO:0043495)
0.1 0.6 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 1.0 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.8 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.4 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.5 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.4 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 3.5 GO:0070063 RNA polymerase binding(GO:0070063)
0.1 0.6 GO:0036310 annealing helicase activity(GO:0036310)
0.1 0.5 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 0.3 GO:0070976 TIR domain binding(GO:0070976)
0.1 0.2 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.6 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 1.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.7 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.5 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 1.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 1.1 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 2.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 1.5 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 0.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.5 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 1.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.5 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.2 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 0.2 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.1 0.7 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.2 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.3 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 0.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.2 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 1.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.1 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.2 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 1.9 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.5 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.6 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 1.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.7 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.3 GO:0023029 MHC class Ib protein binding(GO:0023029)
0.0 0.5 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 1.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 1.1 GO:0004386 helicase activity(GO:0004386)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.2 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.4 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.4 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.9 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.3 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.5 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 3.3 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.5 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 1.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.4 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.7 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 4.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 0.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 3.0 GO:0043130 ubiquitin binding(GO:0043130)
0.0 4.4 GO:0042393 histone binding(GO:0042393)
0.0 0.3 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.3 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 1.9 GO:0008186 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 1.2 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 2.7 GO:0005178 integrin binding(GO:0005178)
0.0 0.7 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.3 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.8 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 1.0 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.1 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.1 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.3 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.7 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 1.0 GO:0031072 heat shock protein binding(GO:0031072)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.4 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.3 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.4 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.1 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 4.0 GO:0016887 ATPase activity(GO:0016887)
0.0 0.7 GO:0003682 chromatin binding(GO:0003682)
0.0 2.7 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.6 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.3 3.8 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 1.9 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.2 1.9 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 13.4 PID_E2F_PATHWAY E2F transcription factor network
0.1 6.7 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.1 8.3 PID_NOTCH_PATHWAY Notch signaling pathway
0.1 6.7 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.1 6.9 PID_PLK1_PATHWAY PLK1 signaling events
0.1 3.8 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 5.1 NABA_COLLAGENS Genes encoding collagen proteins
0.1 1.4 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.1 4.3 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 3.9 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 1.1 PID_ALK2_PATHWAY ALK2 signaling events
0.1 4.8 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 1.4 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.1 2.9 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.1 0.8 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.1 0.3 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.1 1.8 PID_BARD1_PATHWAY BARD1 signaling events
0.1 0.4 PID_FGF_PATHWAY FGF signaling pathway
0.1 1.6 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.1 2.4 PID_RHOA_PATHWAY RhoA signaling pathway
0.1 0.6 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 1.7 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 0.7 PID_FAS_PATHWAY FAS (CD95) signaling pathway
0.0 1.5 PID_IL12_2PATHWAY IL12-mediated signaling events
0.0 2.3 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.7 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 1.1 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.0 0.8 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 1.6 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.2 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.0 0.5 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 2.8 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.5 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.3 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 1.1 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.9 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.8 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.7 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 1.1 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.2 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.6 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.0 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 PID_IL8_CXCR2_PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.2 PID_CD40_PATHWAY CD40/CD40L signaling
0.0 0.3 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.6 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 0.3 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.2 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 0.4 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.3 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.3 PID_CXCR4_PATHWAY CXCR4-mediated signaling events
0.0 0.5 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 0.2 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.1 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.2 PID_MYC_PATHWAY C-MYC pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 0.4 REACTOME_SIGNALING_BY_FGFR3_MUTANTS Genes involved in Signaling by FGFR3 mutants
0.3 6.1 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.3 4.3 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.3 2.1 REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.2 4.2 REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_MULTIPLE_NUCLEOTIDE_PATCH_REPLACEMENT_PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.2 2.7 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.2 1.3 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.2 0.8 REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL Genes involved in NF-kB is activated and signals survival
0.2 2.2 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 0.9 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.6 REACTOME_FGFR2C_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.1 3.0 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.1 6.6 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 2.2 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.1 1.6 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 0.5 REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.1 0.8 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.0 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 1.8 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 2.7 REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.1 2.6 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 1.1 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 1.4 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 2.2 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 2.3 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 2.3 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 2.4 REACTOME_G1_PHASE Genes involved in G1 Phase
0.1 1.4 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 0.6 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.1 1.1 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 2.4 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 4.2 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 0.2 REACTOME_E2F_MEDIATED_REGULATION_OF_DNA_REPLICATION Genes involved in E2F mediated regulation of DNA replication
0.1 2.3 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.3 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.1 1.1 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 0.3 REACTOME_P75NTR_SIGNALS_VIA_NFKB Genes involved in p75NTR signals via NF-kB
0.1 0.7 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 1.6 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 0.5 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.5 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 0.3 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.5 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.2 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS Genes involved in G alpha (q) signalling events
0.0 3.8 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.6 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 1.2 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.9 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.5 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.7 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.8 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.9 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.2 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.1 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.9 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.5 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.8 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.6 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0 1.1 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.4 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.7 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.2 REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.8 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.8 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.4 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.9 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.7 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.5 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.5 REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.2 REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.2 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.2 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME_NOD1_2_SIGNALING_PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.5 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.4 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing