Motif ID: Erg
Z-value: 1.512
Transcription factors associated with Erg:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Erg | ENSMUSG00000040732.12 | Erg |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Erg | mm10_v2_chr16_-_95459245_95459384 | 0.82 | 7.6e-11 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.3 | 9.9 | GO:1905072 | detection of oxygen(GO:0003032) cardiac jelly development(GO:1905072) |
| 2.1 | 22.6 | GO:0042572 | retinol metabolic process(GO:0042572) |
| 1.9 | 7.5 | GO:0050904 | diapedesis(GO:0050904) |
| 1.9 | 5.6 | GO:0070543 | response to linoleic acid(GO:0070543) |
| 1.6 | 8.1 | GO:0003199 | endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) |
| 1.6 | 4.8 | GO:0060913 | stem cell fate specification(GO:0048866) cardiac cell fate determination(GO:0060913) regulation of cardiac cell fate specification(GO:2000043) |
| 1.0 | 12.3 | GO:0061299 | retina vasculature morphogenesis in camera-type eye(GO:0061299) |
| 1.0 | 3.0 | GO:0035696 | monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437) |
| 0.9 | 2.8 | GO:0090187 | zymogen granule exocytosis(GO:0070625) positive regulation of pancreatic juice secretion(GO:0090187) |
| 0.9 | 3.7 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
| 0.9 | 2.7 | GO:0033364 | mast cell secretory granule organization(GO:0033364) |
| 0.9 | 2.6 | GO:0042939 | glutathione transport(GO:0034635) tripeptide transport(GO:0042939) |
| 0.8 | 4.0 | GO:0006447 | regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994) |
| 0.8 | 2.3 | GO:0002432 | granuloma formation(GO:0002432) |
| 0.8 | 7.8 | GO:0071285 | cellular response to lithium ion(GO:0071285) |
| 0.8 | 1.5 | GO:0038091 | VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091) |
| 0.8 | 5.3 | GO:0060762 | regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) |
| 0.8 | 2.3 | GO:0072378 | blood coagulation, fibrin clot formation(GO:0072378) |
| 0.7 | 5.2 | GO:0001955 | blood vessel maturation(GO:0001955) |
| 0.7 | 4.3 | GO:0048597 | post-embryonic camera-type eye morphogenesis(GO:0048597) |
| 0.7 | 2.2 | GO:1900141 | regulation of oligodendrocyte apoptotic process(GO:1900141) negative regulation of oligodendrocyte apoptotic process(GO:1900142) |
| 0.7 | 1.4 | GO:0061010 | gall bladder development(GO:0061010) |
| 0.7 | 4.1 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
| 0.7 | 6.1 | GO:0002693 | positive regulation of cellular extravasation(GO:0002693) |
| 0.7 | 4.7 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
| 0.7 | 2.0 | GO:0002677 | negative regulation of chronic inflammatory response(GO:0002677) |
| 0.6 | 1.7 | GO:0032497 | detection of lipopolysaccharide(GO:0032497) |
| 0.6 | 3.3 | GO:2001204 | regulation of osteoclast development(GO:2001204) |
| 0.5 | 1.6 | GO:2000097 | arachidonic acid metabolite production involved in inflammatory response(GO:0002538) regulation of smooth muscle cell-matrix adhesion(GO:2000097) |
| 0.5 | 3.2 | GO:0035166 | post-embryonic hemopoiesis(GO:0035166) |
| 0.5 | 1.0 | GO:0033278 | cell proliferation in midbrain(GO:0033278) |
| 0.5 | 2.0 | GO:2000318 | positive regulation of T-helper 17 type immune response(GO:2000318) |
| 0.5 | 7.6 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
| 0.5 | 1.4 | GO:0071544 | diphosphoinositol polyphosphate catabolic process(GO:0071544) |
| 0.4 | 1.3 | GO:0070488 | neutrophil aggregation(GO:0070488) |
| 0.4 | 2.0 | GO:0010701 | positive regulation of norepinephrine secretion(GO:0010701) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962) |
| 0.4 | 2.4 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
| 0.4 | 0.8 | GO:0021649 | vestibulocochlear nerve structural organization(GO:0021649) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835) |
| 0.4 | 3.3 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
| 0.4 | 1.4 | GO:0016081 | synaptic vesicle docking(GO:0016081) |
| 0.3 | 0.6 | GO:1901492 | positive regulation of lymphangiogenesis(GO:1901492) |
| 0.3 | 9.4 | GO:0045026 | plasma membrane fusion(GO:0045026) |
| 0.3 | 1.8 | GO:0046549 | retinal cone cell development(GO:0046549) |
| 0.3 | 4.7 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.3 | 3.9 | GO:0032516 | positive regulation of phosphoprotein phosphatase activity(GO:0032516) |
| 0.3 | 3.6 | GO:0050765 | negative regulation of phagocytosis(GO:0050765) |
| 0.2 | 0.7 | GO:0035604 | fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) coronal suture morphogenesis(GO:0060365) squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529) |
| 0.2 | 2.1 | GO:0060613 | fat pad development(GO:0060613) |
| 0.2 | 0.5 | GO:0046544 | development of secondary male sexual characteristics(GO:0046544) |
| 0.2 | 0.9 | GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
| 0.2 | 1.8 | GO:0045651 | positive regulation of macrophage differentiation(GO:0045651) |
| 0.2 | 0.9 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
| 0.2 | 5.1 | GO:0001945 | lymph vessel development(GO:0001945) |
| 0.2 | 1.5 | GO:0060662 | tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662) |
| 0.2 | 0.9 | GO:0060842 | arterial endothelial cell differentiation(GO:0060842) |
| 0.2 | 11.7 | GO:0032481 | positive regulation of type I interferon production(GO:0032481) |
| 0.2 | 2.7 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
| 0.2 | 3.7 | GO:0002042 | cell migration involved in sprouting angiogenesis(GO:0002042) |
| 0.2 | 1.4 | GO:0090241 | negative regulation of histone H4 acetylation(GO:0090241) |
| 0.2 | 1.6 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
| 0.2 | 0.8 | GO:0002681 | somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153) |
| 0.2 | 0.8 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
| 0.2 | 0.6 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
| 0.2 | 15.8 | GO:0016525 | negative regulation of angiogenesis(GO:0016525) |
| 0.2 | 2.4 | GO:0048680 | positive regulation of axon regeneration(GO:0048680) |
| 0.2 | 1.9 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
| 0.2 | 0.9 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
| 0.2 | 2.5 | GO:0006883 | cellular sodium ion homeostasis(GO:0006883) |
| 0.2 | 1.1 | GO:0002002 | regulation of angiotensin levels in blood(GO:0002002) |
| 0.1 | 0.4 | GO:0060437 | lung growth(GO:0060437) |
| 0.1 | 8.1 | GO:2001238 | positive regulation of extrinsic apoptotic signaling pathway(GO:2001238) |
| 0.1 | 0.3 | GO:0050859 | negative regulation of B cell receptor signaling pathway(GO:0050859) |
| 0.1 | 0.4 | GO:0099548 | trans-synaptic signaling by nitric oxide(GO:0099548) |
| 0.1 | 0.1 | GO:0010936 | negative regulation of macrophage cytokine production(GO:0010936) |
| 0.1 | 1.8 | GO:0045792 | negative regulation of cell size(GO:0045792) |
| 0.1 | 0.4 | GO:0098501 | polynucleotide dephosphorylation(GO:0098501) |
| 0.1 | 0.4 | GO:1904975 | response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976) |
| 0.1 | 0.4 | GO:0035526 | retrograde transport, plasma membrane to Golgi(GO:0035526) |
| 0.1 | 0.5 | GO:0010726 | positive regulation of hydrogen peroxide metabolic process(GO:0010726) |
| 0.1 | 0.5 | GO:0006742 | NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364) |
| 0.1 | 0.2 | GO:0048294 | negative regulation of isotype switching to IgE isotypes(GO:0048294) |
| 0.1 | 0.9 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 0.1 | 0.5 | GO:1900170 | negative regulation of glucocorticoid mediated signaling pathway(GO:1900170) |
| 0.1 | 2.0 | GO:0030213 | hyaluronan biosynthetic process(GO:0030213) |
| 0.1 | 0.4 | GO:0090309 | positive regulation of methylation-dependent chromatin silencing(GO:0090309) |
| 0.1 | 0.2 | GO:0032661 | regulation of interleukin-18 production(GO:0032661) negative regulation of interleukin-18 production(GO:0032701) |
| 0.1 | 0.3 | GO:0046880 | regulation of follicle-stimulating hormone secretion(GO:0046880) follicle-stimulating hormone secretion(GO:0046884) |
| 0.1 | 0.9 | GO:2001054 | negative regulation of mesenchymal cell apoptotic process(GO:2001054) |
| 0.1 | 1.1 | GO:0032695 | negative regulation of interleukin-12 production(GO:0032695) |
| 0.1 | 0.7 | GO:0061042 | vascular wound healing(GO:0061042) |
| 0.1 | 0.4 | GO:0046726 | positive regulation by virus of viral protein levels in host cell(GO:0046726) |
| 0.1 | 0.8 | GO:0097369 | sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.1 | 1.0 | GO:0045602 | negative regulation of endothelial cell differentiation(GO:0045602) |
| 0.1 | 0.3 | GO:0001803 | antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805) |
| 0.1 | 0.4 | GO:1904659 | glucose transmembrane transport(GO:1904659) |
| 0.1 | 2.2 | GO:0070207 | protein homotrimerization(GO:0070207) |
| 0.1 | 0.3 | GO:2000110 | negative regulation of macrophage apoptotic process(GO:2000110) |
| 0.1 | 0.5 | GO:0031665 | negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665) |
| 0.1 | 0.9 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
| 0.1 | 2.2 | GO:0035162 | embryonic hemopoiesis(GO:0035162) |
| 0.1 | 0.2 | GO:0006990 | positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) |
| 0.1 | 1.2 | GO:0006817 | phosphate ion transport(GO:0006817) |
| 0.1 | 0.5 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
| 0.1 | 1.1 | GO:0016559 | peroxisome fission(GO:0016559) |
| 0.1 | 0.3 | GO:1904995 | regulation of leukocyte tethering or rolling(GO:1903236) negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995) |
| 0.1 | 0.6 | GO:1901098 | positive regulation of autophagosome maturation(GO:1901098) |
| 0.1 | 0.4 | GO:0007089 | traversing start control point of mitotic cell cycle(GO:0007089) |
| 0.1 | 0.3 | GO:0006624 | vacuolar protein processing(GO:0006624) |
| 0.1 | 0.2 | GO:0008612 | peptidyl-lysine modification to peptidyl-hypusine(GO:0008612) |
| 0.1 | 0.5 | GO:0071361 | cellular response to ethanol(GO:0071361) |
| 0.1 | 1.0 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
| 0.1 | 0.2 | GO:0060316 | positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) |
| 0.1 | 1.6 | GO:0001921 | positive regulation of receptor recycling(GO:0001921) |
| 0.1 | 3.2 | GO:2000649 | regulation of sodium ion transmembrane transporter activity(GO:2000649) |
| 0.1 | 0.5 | GO:0006013 | mannose metabolic process(GO:0006013) |
| 0.1 | 0.8 | GO:0046697 | decidualization(GO:0046697) |
| 0.1 | 0.4 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
| 0.1 | 0.2 | GO:0002946 | tRNA C5-cytosine methylation(GO:0002946) |
| 0.1 | 0.3 | GO:0010747 | positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) |
| 0.0 | 0.1 | GO:0006776 | vitamin A metabolic process(GO:0006776) |
| 0.0 | 0.2 | GO:0010756 | positive regulation of plasminogen activation(GO:0010756) |
| 0.0 | 0.4 | GO:1903003 | positive regulation of protein deubiquitination(GO:1903003) |
| 0.0 | 2.5 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.0 | 0.3 | GO:0030502 | negative regulation of bone mineralization(GO:0030502) |
| 0.0 | 0.7 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.0 | 1.5 | GO:0000038 | very long-chain fatty acid metabolic process(GO:0000038) |
| 0.0 | 1.4 | GO:0031529 | ruffle organization(GO:0031529) |
| 0.0 | 0.3 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 0.0 | 0.2 | GO:0097211 | response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211) |
| 0.0 | 0.2 | GO:0090365 | regulation of mRNA modification(GO:0090365) |
| 0.0 | 1.7 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.0 | 1.6 | GO:0051567 | histone H3-K9 methylation(GO:0051567) |
| 0.0 | 1.8 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
| 0.0 | 0.8 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
| 0.0 | 0.2 | GO:0048102 | autophagic cell death(GO:0048102) |
| 0.0 | 0.7 | GO:0034340 | response to type I interferon(GO:0034340) |
| 0.0 | 0.7 | GO:0060004 | reflex(GO:0060004) |
| 0.0 | 0.2 | GO:0031507 | heterochromatin assembly(GO:0031507) |
| 0.0 | 0.2 | GO:0007000 | nucleolus organization(GO:0007000) |
| 0.0 | 0.8 | GO:0010996 | response to auditory stimulus(GO:0010996) |
| 0.0 | 0.4 | GO:0071157 | negative regulation of cell cycle arrest(GO:0071157) |
| 0.0 | 0.4 | GO:0006903 | vesicle targeting(GO:0006903) |
| 0.0 | 3.1 | GO:0010631 | epithelial cell migration(GO:0010631) |
| 0.0 | 0.1 | GO:2000002 | negative regulation of DNA damage checkpoint(GO:2000002) |
| 0.0 | 0.1 | GO:1903061 | regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061) positive regulation of neuronal action potential(GO:1904457) |
| 0.0 | 0.8 | GO:0043039 | tRNA aminoacylation for protein translation(GO:0006418) tRNA aminoacylation(GO:0043039) |
| 0.0 | 0.3 | GO:0035455 | response to interferon-alpha(GO:0035455) |
| 0.0 | 0.9 | GO:0051496 | positive regulation of stress fiber assembly(GO:0051496) |
| 0.0 | 0.6 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
| 0.0 | 0.1 | GO:0031293 | membrane protein intracellular domain proteolysis(GO:0031293) |
| 0.0 | 0.2 | GO:0045907 | positive regulation of vasoconstriction(GO:0045907) |
| 0.0 | 0.2 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
| 0.0 | 0.3 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.0 | 0.1 | GO:0044854 | plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836) |
| 0.0 | 0.4 | GO:0051591 | response to cAMP(GO:0051591) |
| 0.0 | 0.1 | GO:0031580 | membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) |
| 0.0 | 0.3 | GO:0071526 | semaphorin-plexin signaling pathway(GO:0071526) |
| 0.0 | 0.2 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 0.0 | 0.3 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
| 0.0 | 0.6 | GO:0032543 | mitochondrial translation(GO:0032543) |
| 0.0 | 0.2 | GO:0002091 | negative regulation of receptor internalization(GO:0002091) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.8 | 7.4 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 1.5 | 7.5 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 0.9 | 2.7 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
| 0.7 | 6.8 | GO:0031091 | platelet alpha granule(GO:0031091) |
| 0.6 | 3.2 | GO:0032437 | cuticular plate(GO:0032437) |
| 0.6 | 2.5 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 0.6 | 1.8 | GO:0030690 | Noc1p-Noc2p complex(GO:0030690) |
| 0.6 | 1.8 | GO:0036488 | CHOP-C/EBP complex(GO:0036488) |
| 0.3 | 2.0 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.3 | 2.7 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.3 | 1.6 | GO:0042583 | chromaffin granule(GO:0042583) |
| 0.3 | 0.9 | GO:0045160 | myosin I complex(GO:0045160) |
| 0.3 | 1.7 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.2 | 6.0 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.2 | 1.3 | GO:0032426 | stereocilium tip(GO:0032426) |
| 0.2 | 0.9 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
| 0.2 | 2.3 | GO:0042582 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
| 0.2 | 2.6 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.2 | 4.1 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
| 0.2 | 4.4 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.2 | 1.8 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.1 | 0.7 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.1 | 12.8 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.1 | 6.3 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.1 | 0.8 | GO:0097255 | R2TP complex(GO:0097255) |
| 0.1 | 1.8 | GO:0016460 | myosin II complex(GO:0016460) |
| 0.1 | 0.3 | GO:0043512 | inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512) |
| 0.1 | 10.8 | GO:0005901 | caveola(GO:0005901) |
| 0.1 | 8.0 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.1 | 0.3 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
| 0.1 | 1.3 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 0.1 | 0.6 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 0.1 | 1.0 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.1 | 1.4 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.1 | 0.3 | GO:1990415 | Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429) |
| 0.1 | 2.0 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
| 0.1 | 0.9 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.1 | 0.8 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.0 | 1.1 | GO:0005921 | gap junction(GO:0005921) |
| 0.0 | 1.0 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.0 | 1.9 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.0 | 7.2 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 0.7 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.0 | 0.5 | GO:0016589 | NURF complex(GO:0016589) |
| 0.0 | 14.6 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.0 | 0.2 | GO:0005683 | U7 snRNP(GO:0005683) |
| 0.0 | 0.8 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 5.7 | GO:0043235 | receptor complex(GO:0043235) |
| 0.0 | 2.2 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 4.9 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.0 | 1.4 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.0 | 0.3 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
| 0.0 | 4.9 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.0 | 0.7 | GO:0032420 | stereocilium(GO:0032420) |
| 0.0 | 0.5 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.0 | 9.6 | GO:0009986 | cell surface(GO:0009986) |
| 0.0 | 0.4 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.0 | 0.1 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.0 | 0.1 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 0.0 | 2.4 | GO:0000922 | spindle pole(GO:0000922) |
| 0.0 | 0.1 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.0 | 0.2 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.0 | 0.7 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.0 | 0.1 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 0.0 | 0.6 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 0.7 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.0 | 0.3 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 0.0 | 47.5 | GO:0016021 | integral component of membrane(GO:0016021) |
| 0.0 | 0.1 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.0 | 1.1 | GO:0005769 | early endosome(GO:0005769) |
| 0.0 | 0.3 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.0 | 0.5 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 0.1 | GO:0005687 | U4 snRNP(GO:0005687) |
| 0.0 | 0.5 | GO:0005776 | autophagosome(GO:0005776) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.2 | 22.6 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 2.0 | 9.9 | GO:0005534 | galactose binding(GO:0005534) |
| 1.9 | 5.6 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
| 1.3 | 8.9 | GO:0005021 | vascular endothelial growth factor-activated receptor activity(GO:0005021) |
| 1.0 | 4.1 | GO:0098639 | collagen binding involved in cell-matrix adhesion(GO:0098639) |
| 0.8 | 5.6 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.7 | 2.0 | GO:0019960 | C-X3-C chemokine binding(GO:0019960) |
| 0.7 | 4.0 | GO:0070644 | vitamin D response element binding(GO:0070644) |
| 0.6 | 6.4 | GO:0030169 | low-density lipoprotein particle binding(GO:0030169) |
| 0.6 | 1.7 | GO:0001875 | lipopolysaccharide receptor activity(GO:0001875) |
| 0.6 | 2.3 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 0.5 | 3.7 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
| 0.5 | 1.8 | GO:0035877 | death effector domain binding(GO:0035877) |
| 0.4 | 5.4 | GO:0017081 | chloride channel regulator activity(GO:0017081) |
| 0.4 | 1.2 | GO:0005110 | frizzled-2 binding(GO:0005110) |
| 0.4 | 0.8 | GO:0004921 | interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970) |
| 0.4 | 2.7 | GO:0005127 | ciliary neurotrophic factor receptor binding(GO:0005127) |
| 0.3 | 7.5 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.3 | 1.0 | GO:0015140 | malate transmembrane transporter activity(GO:0015140) |
| 0.3 | 1.0 | GO:0001888 | glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888) |
| 0.3 | 2.5 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
| 0.3 | 1.2 | GO:0005315 | inorganic phosphate transmembrane transporter activity(GO:0005315) |
| 0.3 | 0.9 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
| 0.3 | 0.8 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
| 0.3 | 4.7 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.2 | 11.4 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.2 | 1.4 | GO:0000298 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) |
| 0.2 | 9.2 | GO:0005504 | fatty acid binding(GO:0005504) |
| 0.2 | 2.5 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.2 | 5.4 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.2 | 3.3 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.2 | 3.0 | GO:0005161 | platelet-derived growth factor receptor binding(GO:0005161) |
| 0.2 | 2.0 | GO:0070679 | inositol 1,4,5 trisphosphate binding(GO:0070679) |
| 0.2 | 0.7 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
| 0.1 | 9.9 | GO:0004714 | transmembrane receptor protein tyrosine kinase activity(GO:0004714) |
| 0.1 | 3.3 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
| 0.1 | 0.5 | GO:0038049 | glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
| 0.1 | 1.4 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.1 | 0.6 | GO:1904288 | BAT3 complex binding(GO:1904288) |
| 0.1 | 0.8 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
| 0.1 | 4.7 | GO:0070888 | E-box binding(GO:0070888) |
| 0.1 | 0.4 | GO:0097003 | adiponectin binding(GO:0055100) adipokinetic hormone receptor activity(GO:0097003) |
| 0.1 | 0.5 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.1 | 3.7 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.1 | 10.5 | GO:0008013 | beta-catenin binding(GO:0008013) |
| 0.1 | 0.6 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.1 | 1.5 | GO:0031702 | type 1 angiotensin receptor binding(GO:0031702) |
| 0.1 | 0.3 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.1 | 2.6 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.1 | 2.0 | GO:0035613 | RNA stem-loop binding(GO:0035613) |
| 0.1 | 0.6 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 0.1 | 0.2 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
| 0.1 | 2.3 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.1 | 0.4 | GO:0046403 | polynucleotide 3'-phosphatase activity(GO:0046403) |
| 0.1 | 0.5 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
| 0.1 | 0.6 | GO:0015181 | arginine transmembrane transporter activity(GO:0015181) |
| 0.1 | 1.9 | GO:0005518 | collagen binding(GO:0005518) |
| 0.1 | 0.2 | GO:0015038 | glutathione disulfide oxidoreductase activity(GO:0015038) |
| 0.1 | 3.7 | GO:0030551 | cyclic nucleotide binding(GO:0030551) |
| 0.1 | 1.3 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.1 | 0.1 | GO:0031798 | type 1 metabotropic glutamate receptor binding(GO:0031798) |
| 0.1 | 0.6 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
| 0.1 | 0.9 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.1 | 1.3 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) |
| 0.1 | 0.9 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.1 | 0.3 | GO:0019961 | interferon binding(GO:0019961) |
| 0.1 | 6.1 | GO:0008201 | heparin binding(GO:0008201) |
| 0.1 | 0.2 | GO:0071208 | histone pre-mRNA DCP binding(GO:0071208) |
| 0.1 | 0.3 | GO:0019770 | IgG receptor activity(GO:0019770) |
| 0.1 | 0.4 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 0.1 | 0.3 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
| 0.1 | 1.3 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.0 | 1.0 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.0 | 0.8 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
| 0.0 | 2.8 | GO:0008083 | growth factor activity(GO:0008083) |
| 0.0 | 1.7 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.0 | 5.4 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
| 0.0 | 2.0 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.0 | 6.5 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 0.4 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.0 | 0.2 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.0 | 6.1 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.0 | 1.6 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 2.4 | GO:0019903 | protein phosphatase binding(GO:0019903) |
| 0.0 | 0.1 | GO:0008853 | exodeoxyribonuclease III activity(GO:0008853) |
| 0.0 | 0.6 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.0 | 0.3 | GO:0070290 | phospholipase D activity(GO:0004630) N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
| 0.0 | 0.5 | GO:0004559 | alpha-mannosidase activity(GO:0004559) |
| 0.0 | 0.4 | GO:0004016 | adenylate cyclase activity(GO:0004016) |
| 0.0 | 0.3 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.0 | 0.7 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.0 | 0.2 | GO:0042301 | phosphate ion binding(GO:0042301) |
| 0.0 | 0.4 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.0 | 3.1 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.0 | 0.1 | GO:0001847 | opsonin receptor activity(GO:0001847) |
| 0.0 | 0.2 | GO:0003993 | acid phosphatase activity(GO:0003993) |
| 0.0 | 0.4 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 0.0 | 0.3 | GO:0004467 | long-chain fatty acid-CoA ligase activity(GO:0004467) decanoate--CoA ligase activity(GO:0102391) |
| 0.0 | 0.1 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
| 0.0 | 5.7 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
| 0.0 | 0.2 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.0 | 0.2 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.0 | 0.1 | GO:0004348 | glucosylceramidase activity(GO:0004348) |
| 0.0 | 0.1 | GO:1990050 | phosphatidic acid transporter activity(GO:1990050) |
| 0.0 | 0.2 | GO:0016428 | tRNA (cytosine-5-)-methyltransferase activity(GO:0016428) |
| 0.0 | 0.9 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
| 0.0 | 4.7 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.0 | 0.3 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.0 | 0.4 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.0 | 0.2 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 0.0 | 2.0 | GO:0005516 | calmodulin binding(GO:0005516) |
| 0.0 | 0.2 | GO:0005355 | glucose transmembrane transporter activity(GO:0005355) |
| 0.0 | 0.1 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 2.9 | PID_EPO_PATHWAY | EPO signaling pathway |
| 0.5 | 5.7 | PID_VEGF_VEGFR_PATHWAY | VEGF and VEGFR signaling network |
| 0.4 | 22.1 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.3 | 9.8 | PID_ALK1_PATHWAY | ALK1 signaling events |
| 0.2 | 4.1 | PID_INTEGRIN_CS_PATHWAY | Integrin family cell surface interactions |
| 0.2 | 6.9 | PID_INTEGRIN1_PATHWAY | Beta1 integrin cell surface interactions |
| 0.2 | 6.5 | PID_INTEGRIN3_PATHWAY | Beta3 integrin cell surface interactions |
| 0.2 | 3.0 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
| 0.1 | 2.8 | PID_UPA_UPAR_PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.1 | 3.6 | PID_S1P_S1P2_PATHWAY | S1P2 pathway |
| 0.1 | 4.2 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.1 | 15.5 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 1.5 | PID_PDGFRA_PATHWAY | PDGFR-alpha signaling pathway |
| 0.1 | 1.5 | PID_EPHRINB_REV_PATHWAY | Ephrin B reverse signaling |
| 0.1 | 6.8 | PID_AP1_PATHWAY | AP-1 transcription factor network |
| 0.1 | 11.6 | WNT_SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.1 | 2.2 | PID_ER_NONGENOMIC_PATHWAY | Plasma membrane estrogen receptor signaling |
| 0.1 | 3.0 | ST_TUMOR_NECROSIS_FACTOR_PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.1 | 3.2 | PID_IL3_PATHWAY | IL3-mediated signaling events |
| 0.1 | 2.2 | PID_IL12_STAT4_PATHWAY | IL12 signaling mediated by STAT4 |
| 0.1 | 3.4 | PID_A6B1_A6B4_INTEGRIN_PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.1 | 4.8 | PID_LKB1_PATHWAY | LKB1 signaling events |
| 0.1 | 1.6 | PID_NECTIN_PATHWAY | Nectin adhesion pathway |
| 0.1 | 2.6 | PID_FOXO_PATHWAY | FoxO family signaling |
| 0.1 | 3.3 | PID_HDAC_CLASSII_PATHWAY | Signaling events mediated by HDAC Class II |
| 0.1 | 2.3 | PID_RAS_PATHWAY | Regulation of Ras family activation |
| 0.1 | 10.4 | NABA_SECRETED_FACTORS | Genes encoding secreted soluble factors |
| 0.1 | 0.7 | PID_RAC1_PATHWAY | RAC1 signaling pathway |
| 0.1 | 7.3 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 1.3 | PID_IL4_2PATHWAY | IL4-mediated signaling events |
| 0.1 | 4.6 | PID_MYC_ACTIV_PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 1.1 | ST_GAQ_PATHWAY | G alpha q Pathway |
| 0.0 | 1.5 | PID_HEDGEHOG_GLI_PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.0 | 1.1 | PID_CASPASE_PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 0.4 | PID_TCR_CALCIUM_PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.0 | 0.6 | PID_MYC_REPRESS_PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 0.9 | PID_HES_HEY_PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 0.4 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
| 0.0 | 1.0 | PID_MET_PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.0 | 0.3 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.0 | 0.6 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
| 0.0 | 0.3 | PID_PS1_PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.0 | 0.4 | PID_ECADHERIN_STABILIZATION_PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.0 | 0.4 | PID_RB_1PATHWAY | Regulation of retinoblastoma protein |
| 0.0 | 0.4 | PID_FGF_PATHWAY | FGF signaling pathway |
| 0.0 | 1.6 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 0.2 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
| 0.0 | 0.1 | PID_IL2_1PATHWAY | IL2-mediated signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 3.7 | REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 0.5 | 5.7 | REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.4 | 7.4 | REACTOME_PLATELET_SENSITIZATION_BY_LDL | Genes involved in Platelet sensitization by LDL |
| 0.4 | 8.7 | REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.4 | 2.3 | REACTOME_COMMON_PATHWAY | Genes involved in Common Pathway |
| 0.3 | 10.0 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.2 | 6.8 | REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA | Genes involved in G beta:gamma signalling through PLC beta |
| 0.2 | 15.5 | REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.2 | 4.5 | REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.2 | 1.8 | REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 | Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 |
| 0.2 | 5.2 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.2 | 1.8 | REACTOME_AMINE_DERIVED_HORMONES | Genes involved in Amine-derived hormones |
| 0.2 | 1.7 | REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
| 0.2 | 1.6 | REACTOME_KERATAN_SULFATE_DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.2 | 0.6 | REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.1 | 4.0 | REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.1 | 0.8 | REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
| 0.1 | 2.1 | REACTOME_INTEGRIN_ALPHAIIB_BETA3_SIGNALING | Genes involved in Integrin alphaIIb beta3 signaling |
| 0.1 | 1.4 | REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.1 | 0.9 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.1 | 0.3 | REACTOME_GLYCOPROTEIN_HORMONES | Genes involved in Glycoprotein hormones |
| 0.1 | 11.3 | REACTOME_SIGNALING_BY_PDGF | Genes involved in Signaling by PDGF |
| 0.1 | 2.2 | REACTOME_SIGNALING_BY_SCF_KIT | Genes involved in Signaling by SCF-KIT |
| 0.1 | 0.7 | REACTOME_FGFR2C_LIGAND_BINDING_AND_ACTIVATION | Genes involved in FGFR2c ligand binding and activation |
| 0.1 | 1.5 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.1 | 11.6 | REACTOME_SIGNALING_BY_RHO_GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.1 | 0.8 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |
| 0.1 | 0.4 | REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING | Genes involved in Spry regulation of FGF signaling |
| 0.1 | 2.9 | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.1 | 3.6 | REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.0 | 0.5 | REACTOME_GAP_JUNCTION_ASSEMBLY | Genes involved in Gap junction assembly |
| 0.0 | 0.8 | REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
| 0.0 | 2.2 | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.0 | 1.3 | REACTOME_SYNTHESIS_OF_PA | Genes involved in Synthesis of PA |
| 0.0 | 0.2 | REACTOME_TIE2_SIGNALING | Genes involved in Tie2 Signaling |
| 0.0 | 0.8 | REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.0 | 0.9 | REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.0 | 1.0 | REACTOME_GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.0 | 1.7 | REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.0 | 0.5 | REACTOME_EGFR_DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.0 | 0.3 | REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.0 | 0.7 | REACTOME_LYSOSOME_VESICLE_BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.0 | 0.4 | REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE | Genes involved in Nitric oxide stimulates guanylate cyclase |
| 0.0 | 0.2 | REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.0 | 0.5 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 0.7 | REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION | Genes involved in Antigen processing-Cross presentation |
