Motif ID: Foxl1
Z-value: 0.494
Transcription factors associated with Foxl1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Foxl1 | ENSMUSG00000097084.1 | Foxl1 |
| Foxl1 | ENSMUSG00000043867.5 | Foxl1 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.3 | GO:0035405 | histone-threonine phosphorylation(GO:0035405) |
| 0.2 | 0.7 | GO:0072554 | blood vessel lumenization(GO:0072554) negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588) |
| 0.2 | 1.1 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
| 0.1 | 0.6 | GO:0090126 | protein complex assembly involved in synapse maturation(GO:0090126) |
| 0.1 | 0.3 | GO:0042320 | regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938) |
| 0.1 | 0.5 | GO:0060648 | mammary gland bud morphogenesis(GO:0060648) |
| 0.1 | 0.2 | GO:0003104 | positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643) |
| 0.1 | 0.2 | GO:0007525 | somatic muscle development(GO:0007525) |
| 0.0 | 0.4 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
| 0.0 | 0.3 | GO:1902866 | regulation of retina development in camera-type eye(GO:1902866) |
| 0.0 | 0.1 | GO:0035799 | ureter maturation(GO:0035799) |
| 0.0 | 2.7 | GO:0008542 | visual learning(GO:0008542) |
| 0.0 | 0.3 | GO:0071557 | histone H3-K27 demethylation(GO:0071557) |
| 0.0 | 0.1 | GO:0021557 | oculomotor nerve development(GO:0021557) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) |
| 0.0 | 0.1 | GO:0021529 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) |
| 0.0 | 1.0 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.0 | 0.2 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
| 0.0 | 0.2 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.0 | 0.5 | GO:0060746 | parental behavior(GO:0060746) |
| 0.0 | 0.1 | GO:2000301 | negative regulation of synaptic vesicle exocytosis(GO:2000301) |
| 0.0 | 0.4 | GO:0007129 | synapsis(GO:0007129) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.4 | GO:0097135 | cyclin E2-CDK2 complex(GO:0097135) |
| 0.1 | 0.6 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.0 | 0.3 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.0 | 0.2 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.0 | 1.3 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.0 | 0.1 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.0 | 0.4 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.0 | 2.7 | GO:0043679 | axon terminus(GO:0043679) |
| 0.0 | 0.2 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.3 | GO:0035184 | histone threonine kinase activity(GO:0035184) |
| 0.1 | 2.7 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.0 | 0.2 | GO:0086075 | gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) gap junction channel activity involved in cell communication by electrical coupling(GO:1903763) |
| 0.0 | 0.6 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.0 | 0.4 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.0 | 0.3 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
| 0.0 | 0.5 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
| 0.0 | 0.3 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 0.0 | 0.1 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 0.0 | 0.1 | GO:0004028 | 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
| 0.0 | 0.2 | GO:0032564 | dATP binding(GO:0032564) |
| 0.0 | 0.7 | GO:0005112 | Notch binding(GO:0005112) |
| 0.0 | 0.1 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
| 0.0 | 0.4 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.0 | 2.2 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.3 | PID_TCR_JNK_PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.0 | 2.9 | PID_AP1_PATHWAY | AP-1 transcription factor network |
| 0.0 | 0.4 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.0 | 0.5 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.3 | REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
| 0.0 | 0.7 | REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.0 | 3.0 | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.0 | 0.3 | REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.0 | 0.2 | REACTOME_GAP_JUNCTION_ASSEMBLY | Genes involved in Gap junction assembly |
| 0.0 | 0.4 | REACTOME_G0_AND_EARLY_G1 | Genes involved in G0 and Early G1 |
