Motif ID: Fubp1
Z-value: 0.619
Transcription factors associated with Fubp1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Fubp1 | ENSMUSG00000028034.9 | Fubp1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Fubp1 | mm10_v2_chr3_+_152210458_152210534 | -0.05 | 7.8e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 4.1 | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) |
| 0.3 | 3.0 | GO:0006027 | glycosaminoglycan catabolic process(GO:0006027) |
| 0.3 | 0.8 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) |
| 0.3 | 1.0 | GO:0050904 | diapedesis(GO:0050904) |
| 0.2 | 0.9 | GO:0046552 | eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) |
| 0.2 | 0.6 | GO:0002184 | cytoplasmic translational termination(GO:0002184) |
| 0.2 | 0.6 | GO:0014738 | regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900) |
| 0.2 | 2.6 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
| 0.2 | 0.5 | GO:0046881 | sperm ejaculation(GO:0042713) positive regulation of follicle-stimulating hormone secretion(GO:0046881) |
| 0.1 | 0.7 | GO:1901843 | positive regulation of high voltage-gated calcium channel activity(GO:1901843) |
| 0.1 | 0.6 | GO:0048133 | NK T cell differentiation(GO:0001865) germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138) germline stem cell asymmetric division(GO:0098728) |
| 0.1 | 0.8 | GO:0045200 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) |
| 0.1 | 0.5 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
| 0.1 | 0.5 | GO:1903609 | negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609) |
| 0.1 | 0.3 | GO:0042264 | peptidyl-aspartic acid hydroxylation(GO:0042264) |
| 0.1 | 0.3 | GO:0050883 | regulation of sulfur amino acid metabolic process(GO:0031335) musculoskeletal movement, spinal reflex action(GO:0050883) |
| 0.1 | 0.3 | GO:0061300 | cerebellum vasculature development(GO:0061300) |
| 0.1 | 0.2 | GO:1904580 | regulation of intracellular mRNA localization(GO:1904580) |
| 0.1 | 3.9 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.1 | 0.2 | GO:0060244 | negative regulation of cell proliferation involved in contact inhibition(GO:0060244) |
| 0.1 | 1.7 | GO:0008340 | determination of adult lifespan(GO:0008340) |
| 0.1 | 1.0 | GO:0010669 | epithelial structure maintenance(GO:0010669) |
| 0.1 | 0.4 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
| 0.1 | 5.2 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.1 | 0.3 | GO:1903378 | positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
| 0.0 | 0.2 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
| 0.0 | 0.2 | GO:0021913 | regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) |
| 0.0 | 1.9 | GO:0030901 | midbrain development(GO:0030901) |
| 0.0 | 0.4 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
| 0.0 | 0.2 | GO:0019065 | receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509) |
| 0.0 | 0.2 | GO:1902951 | negative regulation of dendritic spine maintenance(GO:1902951) |
| 0.0 | 0.4 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.0 | 0.1 | GO:0015747 | urate transport(GO:0015747) |
| 0.0 | 0.4 | GO:1902187 | negative regulation of viral release from host cell(GO:1902187) |
| 0.0 | 0.2 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
| 0.0 | 1.0 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
| 0.0 | 0.3 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.0 | 0.1 | GO:0070197 | meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240) |
| 0.0 | 0.1 | GO:0071883 | activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) |
| 0.0 | 1.3 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.0 | 0.2 | GO:0070475 | rRNA base methylation(GO:0070475) |
| 0.0 | 1.0 | GO:0080171 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
| 0.0 | 0.5 | GO:0032292 | myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
| 0.0 | 0.3 | GO:0070266 | necroptotic process(GO:0070266) |
| 0.0 | 0.1 | GO:0016926 | protein desumoylation(GO:0016926) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 4.1 | GO:0043196 | varicosity(GO:0043196) |
| 0.2 | 0.6 | GO:0018444 | translation release factor complex(GO:0018444) |
| 0.2 | 1.0 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 0.2 | 1.0 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
| 0.2 | 0.5 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
| 0.1 | 0.5 | GO:0032585 | multivesicular body membrane(GO:0032585) |
| 0.1 | 1.0 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.1 | 0.3 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 0.1 | 0.2 | GO:0043540 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540) |
| 0.1 | 0.4 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.1 | 0.3 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 0.0 | 0.5 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.0 | 0.2 | GO:0005859 | muscle myosin complex(GO:0005859) |
| 0.0 | 0.8 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.0 | 0.3 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 0.0 | 0.3 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.0 | 0.4 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
| 0.0 | 0.6 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.0 | 0.3 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.0 | 1.2 | GO:0030136 | clathrin-coated vesicle(GO:0030136) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 4.1 | GO:0031749 | D2 dopamine receptor binding(GO:0031749) |
| 0.3 | 0.8 | GO:0004875 | complement receptor activity(GO:0004875) |
| 0.3 | 3.7 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
| 0.2 | 3.0 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.1 | 0.6 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
| 0.1 | 1.0 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.1 | 0.5 | GO:0070320 | inward rectifier potassium channel inhibitor activity(GO:0070320) |
| 0.1 | 0.5 | GO:0017002 | activin-activated receptor activity(GO:0017002) |
| 0.1 | 1.0 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.1 | 0.6 | GO:0003747 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
| 0.1 | 0.6 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.1 | 2.6 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
| 0.1 | 0.3 | GO:0050816 | phosphothreonine binding(GO:0050816) |
| 0.0 | 0.9 | GO:0015026 | coreceptor activity(GO:0015026) |
| 0.0 | 0.3 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.0 | 0.3 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
| 0.0 | 1.0 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.0 | 0.1 | GO:0016509 | long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509) |
| 0.0 | 0.2 | GO:0042610 | CD8 receptor binding(GO:0042610) |
| 0.0 | 0.2 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.0 | 0.2 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
| 0.0 | 0.7 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.0 | 0.2 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
| 0.0 | 0.4 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.0 | 0.4 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.0 | 0.5 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 0.3 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.0 | 0.1 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 0.0 | 0.2 | GO:0050733 | RS domain binding(GO:0050733) |
| 0.0 | 0.2 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.0 | 0.7 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.0 | 0.3 | GO:0030957 | Tat protein binding(GO:0030957) |
| 0.0 | 3.3 | GO:0005516 | calmodulin binding(GO:0005516) |
| 0.0 | 0.3 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 0.3 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.0 | 0.1 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.0 | 0.3 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.0 | 4.0 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.0 | 0.1 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 0.0 | 0.1 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.1 | PID_IL8_CXCR1_PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.0 | 1.4 | PID_ALK1_PATHWAY | ALK1 signaling events |
| 0.0 | 5.9 | NABA_SECRETED_FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 0.9 | PID_BMP_PATHWAY | BMP receptor signaling |
| 0.0 | 0.3 | PID_S1P_S1P1_PATHWAY | S1P1 pathway |
| 0.0 | 1.0 | PID_INTEGRIN3_PATHWAY | Beta3 integrin cell surface interactions |
| 0.0 | 0.3 | PID_HIF1A_PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.0 | 0.3 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 2.7 | REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.2 | 4.1 | REACTOME_GAP_JUNCTION_DEGRADATION | Genes involved in Gap junction degradation |
| 0.1 | 1.2 | REACTOME_PECAM1_INTERACTIONS | Genes involved in PECAM1 interactions |
| 0.1 | 4.6 | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.0 | 1.0 | REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.0 | 0.7 | REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.0 | 0.5 | REACTOME_SIGNALING_BY_NODAL | Genes involved in Signaling by NODAL |
| 0.0 | 0.9 | REACTOME_NETRIN1_SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 0.1 | REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.0 | 0.2 | REACTOME_DESTABILIZATION_OF_MRNA_BY_BRF1 | Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1) |
