Motif ID: Gli1

Z-value: 0.596


Transcription factors associated with Gli1:

Gene SymbolEntrez IDGene Name
Gli1 ENSMUSG00000025407.6 Gli1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gli1mm10_v2_chr10_-_127341583_127341614-0.518.8e-04Click!


Activity profile for motif Gli1.

activity profile for motif Gli1


Sorted Z-values histogram for motif Gli1

Sorted Z-values for motif Gli1



Network of associatons between targets according to the STRING database.



First level regulatory network of Gli1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_68954351 3.062 ENSMUST00000030036.5
Brinp1
bone morphogenic protein/retinoic acid inducible neural specific 1
chr12_-_81333129 2.781 ENSMUST00000085238.6
ENSMUST00000182208.1
Slc8a3

solute carrier family 8 (sodium/calcium exchanger), member 3

chr10_-_64090265 2.715 ENSMUST00000105439.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr5_+_30588078 2.408 ENSMUST00000066295.2
Kcnk3
potassium channel, subfamily K, member 3
chr13_-_114458720 2.316 ENSMUST00000022287.5
Fst
follistatin
chr10_-_64090241 2.292 ENSMUST00000133588.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr11_-_42000284 2.085 ENSMUST00000109292.2
ENSMUST00000109290.1
Gabrg2

gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2

chr15_-_95528228 2.061 ENSMUST00000075275.2
Nell2
NEL-like 2
chr15_-_95528702 2.023 ENSMUST00000166170.1
Nell2
NEL-like 2
chr2_+_118111876 2.008 ENSMUST00000039559.8
Thbs1
thrombospondin 1
chr15_-_85581809 1.956 ENSMUST00000023015.7
Wnt7b
wingless-related MMTV integration site 7B
chr7_+_73391160 1.930 ENSMUST00000128471.1
Rgma
RGM domain family, member A
chr13_-_117025505 1.869 ENSMUST00000022239.6
Parp8
poly (ADP-ribose) polymerase family, member 8
chr2_-_54085542 1.820 ENSMUST00000100089.2
Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chr12_+_44328882 1.684 ENSMUST00000020939.8
ENSMUST00000110748.2
Nrcam

neuron-glia-CAM-related cell adhesion molecule

chr5_+_5573952 1.490 ENSMUST00000101627.2
Gm8773
predicted gene 8773
chr13_+_5861489 1.490 ENSMUST00000000080.6
Klf6
Kruppel-like factor 6
chr11_-_42182163 1.446 ENSMUST00000153147.1
Gabra1
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr11_-_42000532 1.431 ENSMUST00000070735.3
Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr13_+_118714678 1.401 ENSMUST00000022246.8
Fgf10
fibroblast growth factor 10
chr1_-_25228814 1.370 ENSMUST00000126626.1
Bai3
brain-specific angiogenesis inhibitor 3
chr3_+_68494208 1.251 ENSMUST00000182719.1
Schip1
schwannomin interacting protein 1
chr8_+_54954728 1.226 ENSMUST00000033915.7
Gpm6a
glycoprotein m6a
chr8_+_70501116 1.206 ENSMUST00000127983.1
Crlf1
cytokine receptor-like factor 1
chr10_+_40883819 1.136 ENSMUST00000105509.1
Wasf1
WAS protein family, member 1
chrX_-_59568068 1.127 ENSMUST00000119833.1
ENSMUST00000131319.1
Fgf13

fibroblast growth factor 13

chr18_-_70141568 1.049 ENSMUST00000121693.1
Rab27b
RAB27b, member RAS oncogene family
chrX_+_119927196 1.015 ENSMUST00000040961.2
ENSMUST00000113366.1
Pabpc5

poly(A) binding protein, cytoplasmic 5

chr6_-_28830345 1.006 ENSMUST00000171353.1
Lrrc4
leucine rich repeat containing 4
chr6_-_52012476 0.991 ENSMUST00000078214.5
Skap2
src family associated phosphoprotein 2
chr2_+_119351222 0.984 ENSMUST00000028780.3
Chac1
ChaC, cation transport regulator 1
chr2_-_92434027 0.976 ENSMUST00000111278.1
ENSMUST00000090559.5
Cry2

cryptochrome 2 (photolyase-like)

chr3_+_45378396 0.974 ENSMUST00000166126.1
ENSMUST00000170695.1
ENSMUST00000171554.1
Pcdh10


protocadherin 10


chrX_+_101299143 0.969 ENSMUST00000118111.1
ENSMUST00000130555.1
ENSMUST00000151528.1
Nlgn3


neuroligin 3


chr13_+_81783220 0.961 ENSMUST00000022009.8
Cetn3
centrin 3
chrX_+_101299207 0.930 ENSMUST00000065858.2
Nlgn3
neuroligin 3
chr13_+_109685994 0.921 ENSMUST00000074103.5
Pde4d
phosphodiesterase 4D, cAMP specific
chr1_-_56972437 0.860 ENSMUST00000042857.7
Satb2
special AT-rich sequence binding protein 2
chr14_-_41008256 0.831 ENSMUST00000136661.1
Fam213a
family with sequence similarity 213, member A
chr7_-_138397704 0.820 ENSMUST00000160436.1
Tcerg1l
transcription elongation regulator 1-like
chr1_+_152954966 0.815 ENSMUST00000043313.8
Nmnat2
nicotinamide nucleotide adenylyltransferase 2
chr4_+_106561027 0.797 ENSMUST00000047973.3
Dhcr24
24-dehydrocholesterol reductase
chr17_+_34187545 0.751 ENSMUST00000170086.1
Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr17_+_34187789 0.736 ENSMUST00000041633.8
Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr6_+_107529717 0.683 ENSMUST00000049285.8
Lrrn1
leucine rich repeat protein 1, neuronal
chrX_+_155262443 0.681 ENSMUST00000026324.9
Acot9
acyl-CoA thioesterase 9
chr6_+_108213086 0.675 ENSMUST00000032192.6
Itpr1
inositol 1,4,5-trisphosphate receptor 1
chr17_-_84790517 0.657 ENSMUST00000112308.2
Lrpprc
leucine-rich PPR-motif containing
chrX_+_94234594 0.625 ENSMUST00000153900.1
Klhl15
kelch-like 15
chr6_+_95117740 0.623 ENSMUST00000032107.7
ENSMUST00000119582.1
Kbtbd8

kelch repeat and BTB (POZ) domain containing 8

chr18_-_43373248 0.620 ENSMUST00000118043.1
Dpysl3
dihydropyrimidinase-like 3
chr17_+_37045963 0.611 ENSMUST00000025338.9
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr11_+_97840780 0.582 ENSMUST00000054783.4
B230217C12Rik
RIKEN cDNA B230217C12 gene
chr9_+_86695542 0.579 ENSMUST00000150367.2
A330041J22Rik
RIKEN cDNA A330041J22 gene
chrX_-_59567348 0.570 ENSMUST00000124402.1
Fgf13
fibroblast growth factor 13
chr8_-_64733534 0.551 ENSMUST00000141021.1
Sc4mol
sterol-C4-methyl oxidase-like
chr10_-_63421739 0.538 ENSMUST00000054760.4
Gm7075
predicted gene 7075
chr4_+_12140263 0.528 ENSMUST00000050069.2
ENSMUST00000069128.7
Rbm12b1

RNA binding motif protein 12 B1

chrX_+_159303266 0.527 ENSMUST00000112491.1
Rps6ka3
ribosomal protein S6 kinase polypeptide 3
chr7_+_28982832 0.519 ENSMUST00000085835.6
Map4k1
mitogen-activated protein kinase kinase kinase kinase 1
chr19_-_5085483 0.515 ENSMUST00000140389.1
ENSMUST00000151413.1
ENSMUST00000077066.7
Tmem151a


transmembrane protein 151A


chr6_-_113531575 0.510 ENSMUST00000032425.5
Emc3
ER membrane protein complex subunit 3
chr14_+_45351473 0.475 ENSMUST00000111835.2
Styx
serine/threonine/tyrosine interaction protein
chr18_+_37477768 0.468 ENSMUST00000051442.5
Pcdhb16
protocadherin beta 16
chr17_-_24209377 0.463 ENSMUST00000024931.4
Ntn3
netrin 3
chr1_-_153900198 0.442 ENSMUST00000123490.1
5830403L16Rik
RIKEN cDNA 5830403L16 gene
chr16_-_91011029 0.399 ENSMUST00000130813.1
Synj1
synaptojanin 1
chr10_+_69533761 0.395 ENSMUST00000182884.1
Ank3
ankyrin 3, epithelial
chr2_-_152830615 0.392 ENSMUST00000146380.1
ENSMUST00000134902.1
ENSMUST00000134357.1
ENSMUST00000109820.3
Bcl2l1



BCL2-like 1



chr2_+_23069057 0.384 ENSMUST00000114526.1
ENSMUST00000114529.2
Acbd5

acyl-Coenzyme A binding domain containing 5

chr4_-_43454600 0.378 ENSMUST00000098105.3
ENSMUST00000098104.3
ENSMUST00000030179.4
Cd72


CD72 antigen


chr1_+_153900572 0.378 ENSMUST00000139476.1
Glul
glutamate-ammonia ligase (glutamine synthetase)
chr12_+_24498570 0.371 ENSMUST00000075954.7
Taf1b
TATA box binding protein (Tbp)-associated factor, RNA polymerase I, B
chr4_-_58553184 0.366 ENSMUST00000145361.1
Lpar1
lysophosphatidic acid receptor 1
chr11_+_35769462 0.362 ENSMUST00000018990.7
Pank3
pantothenate kinase 3
chr2_-_104494400 0.348 ENSMUST00000028600.7
Hipk3
homeodomain interacting protein kinase 3
chr1_+_72824482 0.344 ENSMUST00000047328.4
Igfbp2
insulin-like growth factor binding protein 2
chr18_-_35662180 0.344 ENSMUST00000025209.4
ENSMUST00000096573.2
Spata24

spermatogenesis associated 24

chr15_-_56694525 0.341 ENSMUST00000050544.7
Has2
hyaluronan synthase 2
chr2_+_181520485 0.341 ENSMUST00000072334.5
Dnajc5
DnaJ (Hsp40) homolog, subfamily C, member 5
chr4_+_12089373 0.334 ENSMUST00000095143.2
ENSMUST00000063839.5
Rbm12b2

RNA binding motif protein 12 B2

chr2_+_119034783 0.332 ENSMUST00000028796.1
Rpusd2
RNA pseudouridylate synthase domain containing 2
chr15_-_80264276 0.329 ENSMUST00000052499.7
Rps19bp1
ribosomal protein S19 binding protein 1
chr2_-_104493690 0.323 ENSMUST00000111124.1
Hipk3
homeodomain interacting protein kinase 3
chr16_-_91011093 0.323 ENSMUST00000170853.1
ENSMUST00000118390.2
Synj1

synaptojanin 1

chr2_-_30801698 0.309 ENSMUST00000050003.8
1700001O22Rik
RIKEN cDNA 1700001O22 gene
chr2_-_152831112 0.300 ENSMUST00000128172.1
Bcl2l1
BCL2-like 1
chr6_+_37870786 0.298 ENSMUST00000120428.1
ENSMUST00000031859.7
Trim24

tripartite motif-containing 24

chr5_-_32746272 0.294 ENSMUST00000120591.1
Pisd
phosphatidylserine decarboxylase
chr4_-_40948196 0.292 ENSMUST00000030125.4
ENSMUST00000108089.1
Bag1

BCL2-associated athanogene 1

chr10_+_69533803 0.290 ENSMUST00000182155.1
ENSMUST00000183169.1
ENSMUST00000183148.1
Ank3


ankyrin 3, epithelial


chr1_+_129273344 0.276 ENSMUST00000073527.6
ENSMUST00000040311.7
Thsd7b

thrombospondin, type I, domain containing 7B

chr2_+_23069210 0.274 ENSMUST00000155602.1
Acbd5
acyl-Coenzyme A binding domain containing 5
chr5_-_115300957 0.273 ENSMUST00000009157.3
Dynll1
dynein light chain LC8-type 1
chr13_-_9764943 0.272 ENSMUST00000110634.1
Zmynd11
zinc finger, MYND domain containing 11
chr11_-_78245942 0.271 ENSMUST00000002121.4
Supt6
suppressor of Ty 6
chr2_-_103797617 0.268 ENSMUST00000028607.6
Caprin1
cell cycle associated protein 1
chr11_-_69920892 0.255 ENSMUST00000152589.1
ENSMUST00000108612.1
ENSMUST00000108611.1
Eif5a


eukaryotic translation initiation factor 5A


chr2_-_93046053 0.252 ENSMUST00000111272.1
ENSMUST00000178666.1
ENSMUST00000147339.1
Prdm11


PR domain containing 11


chr10_+_69534039 0.252 ENSMUST00000182557.1
Ank3
ankyrin 3, epithelial
chr2_+_181520533 0.234 ENSMUST00000108797.1
Dnajc5
DnaJ (Hsp40) homolog, subfamily C, member 5
chr7_-_6331235 0.224 ENSMUST00000127658.1
ENSMUST00000062765.7
Zfp583

zinc finger protein 583

chr15_+_99392882 0.224 ENSMUST00000023749.8
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr5_-_115300912 0.224 ENSMUST00000112090.1
Dynll1
dynein light chain LC8-type 1
chr2_-_36104060 0.221 ENSMUST00000112961.3
ENSMUST00000112966.3
Lhx6

LIM homeobox protein 6

chr4_-_58553311 0.215 ENSMUST00000107571.1
ENSMUST00000055018.4
Lpar1

lysophosphatidic acid receptor 1

chr4_-_43454582 0.204 ENSMUST00000107925.1
Cd72
CD72 antigen
chr15_+_34082664 0.201 ENSMUST00000022865.9
Mtdh
metadherin
chr5_-_110779937 0.199 ENSMUST00000112426.1
Pus1
pseudouridine synthase 1
chr5_-_32746317 0.183 ENSMUST00000135248.1
Pisd
phosphatidylserine decarboxylase
chr4_-_43454563 0.181 ENSMUST00000107926.1
Cd72
CD72 antigen
chr2_+_157560078 0.178 ENSMUST00000153739.2
ENSMUST00000173595.1
ENSMUST00000109526.1
ENSMUST00000173839.1
ENSMUST00000173041.1
ENSMUST00000173793.1
ENSMUST00000172487.1
ENSMUST00000088484.5
Nnat







neuronatin







chr3_-_89402650 0.174 ENSMUST00000168325.1
ENSMUST00000057431.5
Lenep

lens epithelial protein

chr19_-_6084679 0.173 ENSMUST00000161548.1
Zfpl1
zinc finger like protein 1
chr5_-_123721007 0.171 ENSMUST00000031376.7
Zcchc8
zinc finger, CCHC domain containing 8
chr19_-_3575708 0.144 ENSMUST00000113997.2
ENSMUST00000025846.8
ENSMUST00000172362.1
Ppp6r3


protein phosphatase 6, regulatory subunit 3


chr1_-_64121456 0.144 ENSMUST00000142009.1
ENSMUST00000114086.1
Klf7

Kruppel-like factor 7 (ubiquitous)

chr10_+_69534208 0.143 ENSMUST00000182439.1
ENSMUST00000092434.5
ENSMUST00000092432.5
ENSMUST00000092431.5
ENSMUST00000054167.8
ENSMUST00000047061.6
Ank3





ankyrin 3, epithelial





chr11_+_115420059 0.142 ENSMUST00000103035.3
Kctd2
potassium channel tetramerisation domain containing 2
chr9_-_110117379 0.142 ENSMUST00000111991.2
ENSMUST00000149199.1
ENSMUST00000035056.7
ENSMUST00000148287.1
ENSMUST00000127744.1
Dhx30




DEAH (Asp-Glu-Ala-His) box polypeptide 30




chr1_-_125912160 0.132 ENSMUST00000159417.1
Lypd1
Ly6/Plaur domain containing 1
chr3_+_88553716 0.130 ENSMUST00000008748.6
Ubqln4
ubiquilin 4
chr7_+_141216626 0.128 ENSMUST00000141804.1
ENSMUST00000148975.1
Rassf7

Ras association (RalGDS/AF-6) domain family (N-terminal) member 7

chr4_-_147848358 0.127 ENSMUST00000105718.1
ENSMUST00000135798.1
Zfp933

zinc finger protein 933

chr5_-_122989086 0.126 ENSMUST00000046073.9
Kdm2b
lysine (K)-specific demethylase 2B
chr18_-_10610124 0.123 ENSMUST00000097670.3
Esco1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr15_+_99392948 0.122 ENSMUST00000161250.1
ENSMUST00000160635.1
ENSMUST00000161778.1
Tmbim6


transmembrane BAX inhibitor motif containing 6


chr9_+_110305185 0.121 ENSMUST00000068071.7
Elp6
elongator acetyltransferase complex subunit 6
chr4_-_41275091 0.119 ENSMUST00000030143.6
ENSMUST00000108068.1
Ubap2

ubiquitin-associated protein 2

chr11_+_51619731 0.115 ENSMUST00000127405.1
Nhp2
NHP2 ribonucleoprotein
chr19_+_55316313 0.113 ENSMUST00000095950.2
Vti1a
vesicle transport through interaction with t-SNAREs 1A
chr18_-_10610346 0.110 ENSMUST00000025142.5
Esco1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr1_-_64121389 0.109 ENSMUST00000055001.3
Klf7
Kruppel-like factor 7 (ubiquitous)
chr17_+_25727726 0.107 ENSMUST00000047273.1
Rpusd1
RNA pseudouridylate synthase domain containing 1
chr18_-_10610048 0.103 ENSMUST00000115864.1
Esco1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr4_-_133874682 0.101 ENSMUST00000168974.2
Rps6ka1
ribosomal protein S6 kinase polypeptide 1
chr14_+_55560480 0.101 ENSMUST00000121622.1
ENSMUST00000143431.1
ENSMUST00000150481.1
Dcaf11


DDB1 and CUL4 associated factor 11


chr11_+_77763246 0.099 ENSMUST00000108375.2
Myo18a
myosin XVIIIA
chr11_+_78245743 0.077 ENSMUST00000002133.8
Sdf2
stromal cell derived factor 2
chr2_+_29890534 0.070 ENSMUST00000113764.3
Odf2
outer dense fiber of sperm tails 2
chr11_+_115420138 0.070 ENSMUST00000106533.1
ENSMUST00000123345.1
Kctd2

potassium channel tetramerisation domain containing 2

chr4_-_58553553 0.067 ENSMUST00000107575.2
ENSMUST00000107574.1
ENSMUST00000147354.1
Lpar1


lysophosphatidic acid receptor 1


chr2_+_15055274 0.067 ENSMUST00000069870.3
Arl5b
ADP-ribosylation factor-like 5B
chr11_+_70214105 0.066 ENSMUST00000094055.3
ENSMUST00000136328.1
ENSMUST00000126296.1
ENSMUST00000153993.2
Slc16a11



solute carrier family 16 (monocarboxylic acid transporters), member 11



chr4_+_74251928 0.064 ENSMUST00000030102.5
Kdm4c
lysine (K)-specific demethylase 4C
chr16_-_90284412 0.064 ENSMUST00000039280.7
Scaf4
SR-related CTD-associated factor 4
chr9_-_54661666 0.045 ENSMUST00000128624.1
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr4_+_123233556 0.035 ENSMUST00000040821.4
Heyl
hairy/enhancer-of-split related with YRPW motif-like
chr2_+_20737306 0.031 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr4_+_108847827 0.028 ENSMUST00000102738.2
Kti12
KTI12 homolog, chromatin associated (S. cerevisiae)
chr14_+_60378242 0.028 ENSMUST00000022561.6
Amer2
APC membrane recruitment 2
chr11_+_23306910 0.024 ENSMUST00000137823.1
Usp34
ubiquitin specific peptidase 34
chr16_-_56024628 0.021 ENSMUST00000119981.1
ENSMUST00000096021.3
Pcnp

PEST proteolytic signal containing nuclear protein

chr1_+_195017399 0.021 ENSMUST00000181273.1
A330023F24Rik
RIKEN cDNA A330023F24 gene
chr15_-_100669512 0.019 ENSMUST00000182574.1
ENSMUST00000182775.1
Bin2

bridging integrator 2

chr8_-_72213636 0.014 ENSMUST00000109987.1
Gm11034
predicted gene 11034
chrX_-_60893430 0.013 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0010752 negative regulation of antigen processing and presentation(GO:0002578) regulation of cGMP-mediated signaling(GO:0010752)
0.7 2.0 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.6 1.9 GO:2000331 regulation of terminal button organization(GO:2000331)
0.6 2.8 GO:1990034 calcium ion export from cell(GO:1990034)
0.6 5.0 GO:0071420 cellular response to histamine(GO:0071420)
0.5 1.4 GO:0071336 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.4 1.5 GO:0046967 cytosol to ER transport(GO:0046967)
0.4 4.1 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.3 5.0 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.3 1.0 GO:2000850 protein-chromophore linkage(GO:0018298) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.3 2.3 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.3 1.7 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 1.5 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.2 1.0 GO:0006751 glutathione catabolic process(GO:0006751)
0.2 1.7 GO:0098909 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.2 0.7 GO:1904978 regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
0.2 2.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 0.8 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.2 1.0 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.2 1.9 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.2 0.7 GO:0046898 response to cycloheximide(GO:0046898)
0.2 0.7 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.2 1.1 GO:1990416 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.2 0.6 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.2 0.5 GO:0045204 MAPK export from nucleus(GO:0045204)
0.2 3.1 GO:0042711 maternal behavior(GO:0042711)
0.1 0.4 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.1 0.4 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.1 0.3 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.1 0.7 GO:0042045 epithelial fluid transport(GO:0042045)
0.1 0.6 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 1.1 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.7 GO:0030242 pexophagy(GO:0030242)
0.1 1.3 GO:0001553 luteinization(GO:0001553)
0.1 0.9 GO:1901898 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.3 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.1 0.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 1.0 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.1 0.8 GO:0031639 plasminogen activation(GO:0031639)
0.1 0.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.4 GO:0032811 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of epinephrine secretion(GO:0032811)
0.1 0.3 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 0.6 GO:0014029 neural crest formation(GO:0014029)
0.1 0.6 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.1 0.3 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086) chromatin maintenance(GO:0070827)
0.1 0.9 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.7 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.5 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.3 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.6 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:1903028 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.0 0.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 1.2 GO:0003407 neural retina development(GO:0003407)
0.0 0.3 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.0 0.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.3 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0005577 fibrinogen complex(GO:0005577)
0.4 1.2 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.3 5.0 GO:1902711 GABA-A receptor complex(GO:1902711)
0.2 0.7 GO:0031088 platelet dense granule membrane(GO:0031088)
0.2 1.5 GO:0042825 TAP complex(GO:0042825)
0.2 1.0 GO:0032585 multivesicular body membrane(GO:0032585)
0.1 1.1 GO:0031209 SCAR complex(GO:0031209)
0.1 0.4 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 2.8 GO:0043194 axon initial segment(GO:0043194)
0.1 0.4 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 0.7 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 1.7 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 1.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.5 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 2.8 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.5 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.1 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.0 2.9 GO:0030175 filopodium(GO:0030175)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.7 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.3 GO:0005642 annulate lamellae(GO:0005642)
0.0 3.1 GO:0043204 perikaryon(GO:0043204)
0.0 1.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.8 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 3.9 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 1.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.6 GO:0031941 filamentous actin(GO:0031941)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0070052 collagen V binding(GO:0070052)
0.5 2.0 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.4 1.5 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.4 1.4 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.3 1.7 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.3 1.0 GO:0009881 photoreceptor activity(GO:0009881)
0.3 2.8 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.3 5.0 GO:0004890 GABA-A receptor activity(GO:0004890)
0.2 0.7 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.2 0.7 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.2 2.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 2.3 GO:0048185 activin binding(GO:0048185)
0.2 0.8 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.2 1.0 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.2 1.2 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 1.9 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 0.7 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 0.4 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.5 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 1.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.6 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 1.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.7 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.4 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.4 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.6 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.3 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 6.0 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 4.1 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.0 GO:0031489 myosin V binding(GO:0031489)
0.0 0.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.3 GO:0034056 estrogen response element binding(GO:0034056)
0.0 2.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.5 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.8 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.9 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.6 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.3 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.4 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.7 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 1.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 1.1 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.0 GO:0035939 microsatellite binding(GO:0035939)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.2 PID_BMP_PATHWAY BMP receptor signaling
0.1 2.0 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 1.0 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 6.5 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 2.1 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.7 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.5 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.7 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.1 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 3.4 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 0.7 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.0 0.8 PID_BCR_5PATHWAY BCR signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.4 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.3 5.0 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.2 2.8 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 1.4 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.1 1.5 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 2.8 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.0 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.7 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.0 1.9 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.6 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.8 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.4 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.5 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 2.0 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.3 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.9 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 1.0 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.3 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.7 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.7 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.8 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.4 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.4 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.6 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.0 0.4 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.4 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.5 REACTOME_MYOGENESIS Genes involved in Myogenesis