Motif ID: Gmeb2

Z-value: 0.753


Transcription factors associated with Gmeb2:

Gene SymbolEntrez IDGene Name
Gmeb2 ENSMUSG00000038705.7 Gmeb2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gmeb2mm10_v2_chr2_-_181288016_1812880410.296.8e-02Click!


Activity profile for motif Gmeb2.

activity profile for motif Gmeb2


Sorted Z-values histogram for motif Gmeb2

Sorted Z-values for motif Gmeb2



Network of associatons between targets according to the STRING database.



First level regulatory network of Gmeb2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_78544345 3.206 ENSMUST00000053239.2
Sstr3
somatostatin receptor 3
chr1_+_185454803 3.094 ENSMUST00000061093.6
Slc30a10
solute carrier family 30, member 10
chr7_+_66839726 2.366 ENSMUST00000098382.3
Adamts17
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17
chr1_-_77515048 2.328 ENSMUST00000027451.6
Epha4
Eph receptor A4
chr7_+_66839752 2.280 ENSMUST00000107478.1
Adamts17
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17
chr3_+_127553462 1.926 ENSMUST00000043108.4
4930422G04Rik
RIKEN cDNA 4930422G04 gene
chr7_+_79660196 1.734 ENSMUST00000035977.7
Ticrr
TOPBP1-interacting checkpoint and replication regulator
chr4_+_101419696 1.729 ENSMUST00000131397.1
ENSMUST00000133055.1
Ak4

adenylate kinase 4

chr12_+_102554966 1.649 ENSMUST00000021610.5
Chga
chromogranin A
chr10_-_42583628 1.616 ENSMUST00000019938.4
Nr2e1
nuclear receptor subfamily 2, group E, member 1
chr5_-_31291026 1.527 ENSMUST00000041565.7
Ift172
intraflagellar transport 172
chr15_-_50889691 1.516 ENSMUST00000165201.2
ENSMUST00000184458.1
Trps1

trichorhinophalangeal syndrome I (human)

chr9_-_56928350 1.503 ENSMUST00000050916.5
Snx33
sorting nexin 33
chr2_+_109280738 1.396 ENSMUST00000028527.7
Kif18a
kinesin family member 18A
chr15_+_82016420 1.393 ENSMUST00000168581.1
ENSMUST00000170630.1
ENSMUST00000164779.1
Xrcc6


X-ray repair complementing defective repair in Chinese hamster cells 6


chr3_-_95217690 1.365 ENSMUST00000107209.1
Gabpb2
GA repeat binding protein, beta 2
chr4_+_101419277 1.363 ENSMUST00000102780.1
ENSMUST00000106946.1
ENSMUST00000106945.1
Ak4


adenylate kinase 4


chr2_-_53191214 1.320 ENSMUST00000076313.6
ENSMUST00000125243.1
Prpf40a

PRP40 pre-mRNA processing factor 40 homolog A (yeast)

chr6_-_39725193 1.296 ENSMUST00000101497.3
Braf
Braf transforming gene
chr4_-_109665249 1.277 ENSMUST00000063531.4
Cdkn2c
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr13_+_81657732 1.244 ENSMUST00000049055.6
Lysmd3
LysM, putative peptidoglycan-binding, domain containing 3
chr3_+_131110350 1.241 ENSMUST00000066849.6
ENSMUST00000106341.2
ENSMUST00000029611.7
Lef1


lymphoid enhancer binding factor 1


chr11_+_23665615 1.240 ENSMUST00000109525.1
ENSMUST00000020520.4
Pus10

pseudouridylate synthase 10

chr4_+_44756553 1.230 ENSMUST00000107824.2
Zcchc7
zinc finger, CCHC domain containing 7
chr1_+_82316452 1.229 ENSMUST00000027322.7
Rhbdd1
rhomboid domain containing 1
chr3_-_95217877 1.228 ENSMUST00000136139.1
Gabpb2
GA repeat binding protein, beta 2
chr13_+_49653297 1.185 ENSMUST00000021824.7
Nol8
nucleolar protein 8
chr1_-_162740350 1.147 ENSMUST00000182331.1
ENSMUST00000183011.1
ENSMUST00000182593.1
ENSMUST00000182149.1
Prrc2c



proline-rich coiled-coil 2C



chr4_-_40269778 1.138 ENSMUST00000042575.6
Topors
topoisomerase I binding, arginine/serine-rich
chr6_+_21949571 1.136 ENSMUST00000031680.3
ENSMUST00000115389.1
ENSMUST00000151473.1
Ing3


inhibitor of growth family, member 3


chr9_-_123717576 1.126 ENSMUST00000026274.7
Lztfl1
leucine zipper transcription factor-like 1
chr11_+_78301529 1.121 ENSMUST00000045026.3
Spag5
sperm associated antigen 5
chr1_-_156035891 1.117 ENSMUST00000126448.1
Tor1aip1
torsin A interacting protein 1
chr1_-_162740540 1.113 ENSMUST00000028016.9
ENSMUST00000182660.1
Prrc2c

proline-rich coiled-coil 2C

chr12_+_111039334 1.109 ENSMUST00000084968.7
Rcor1
REST corepressor 1
chr4_-_34882919 1.106 ENSMUST00000098163.2
ENSMUST00000047950.5
Zfp292

zinc finger protein 292

chr1_-_55027473 1.094 ENSMUST00000027127.7
Sf3b1
splicing factor 3b, subunit 1
chr10_+_58446845 1.090 ENSMUST00000003310.5
Ranbp2
RAN binding protein 2
chr16_-_91044473 1.089 ENSMUST00000118522.1
Paxbp1
PAX3 and PAX7 binding protein 1
chr11_-_40733373 1.081 ENSMUST00000020579.8
Hmmr
hyaluronan mediated motility receptor (RHAMM)
chr7_-_119896285 1.051 ENSMUST00000106519.1
Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr4_+_44756609 1.044 ENSMUST00000143385.1
Zcchc7
zinc finger, CCHC domain containing 7
chr8_+_110079758 1.017 ENSMUST00000058804.8
Zfp612
zinc finger protein 612
chr15_+_82016369 1.002 ENSMUST00000069530.6
Xrcc6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr14_-_45219364 0.992 ENSMUST00000022377.4
ENSMUST00000143609.1
ENSMUST00000139526.1
Txndc16


thioredoxin domain containing 16


chr7_-_119895697 0.989 ENSMUST00000059851.6
Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr2_-_37703845 0.989 ENSMUST00000155237.1
Strbp
spermatid perinuclear RNA binding protein
chr1_-_156036473 0.974 ENSMUST00000097527.3
ENSMUST00000027738.7
Tor1aip1

torsin A interacting protein 1

chr9_+_72985410 0.894 ENSMUST00000037977.8
Ccpg1
cell cycle progression 1
chr3_-_95217741 0.869 ENSMUST00000107204.1
Gabpb2
GA repeat binding protein, beta 2
chr6_-_39725448 0.868 ENSMUST00000002487.8
Braf
Braf transforming gene
chr11_+_93886157 0.855 ENSMUST00000063718.4
ENSMUST00000107854.2
Mbtd1

mbt domain containing 1

chr18_+_36281069 0.816 ENSMUST00000051301.3
Pura
purine rich element binding protein A
chr7_+_27591705 0.811 ENSMUST00000167435.1
Akt2
thymoma viral proto-oncogene 2
chr7_-_138846202 0.805 ENSMUST00000118810.1
ENSMUST00000075667.4
ENSMUST00000119664.1
Mapk1ip1


mitogen-activated protein kinase 1 interacting protein 1


chr7_-_35802968 0.774 ENSMUST00000061586.4
Zfp507
zinc finger protein 507
chr17_-_94749874 0.766 ENSMUST00000171284.1
Mettl4
methyltransferase like 4
chr1_-_161034794 0.752 ENSMUST00000177003.1
ENSMUST00000162226.2
ENSMUST00000159250.2
Zbtb37


zinc finger and BTB domain containing 37


chr17_+_86963077 0.749 ENSMUST00000024956.8
Rhoq
ras homolog gene family, member Q
chr13_+_83721357 0.747 ENSMUST00000131907.2
C130071C03Rik
RIKEN cDNA C130071C03 gene
chrX_+_152016428 0.730 ENSMUST00000045312.5
Smc1a
structural maintenance of chromosomes 1A
chr7_+_127841817 0.730 ENSMUST00000121705.1
Stx4a
syntaxin 4A (placental)
chr7_-_119895446 0.703 ENSMUST00000098080.2
Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr2_+_69722797 0.674 ENSMUST00000090858.3
Ppig
peptidyl-prolyl isomerase G (cyclophilin G)
chr2_+_69723071 0.673 ENSMUST00000040915.8
Ppig
peptidyl-prolyl isomerase G (cyclophilin G)
chr9_-_75409951 0.672 ENSMUST00000049355.10
Mapk6
mitogen-activated protein kinase 6
chr16_+_14361552 0.671 ENSMUST00000100167.3
ENSMUST00000154748.1
ENSMUST00000134776.1
Abcc1


ATP-binding cassette, sub-family C (CFTR/MRP), member 1


chr2_-_77946331 0.644 ENSMUST00000111821.2
ENSMUST00000111818.1
Cwc22

CWC22 spliceosome-associated protein homolog (S. cerevisiae)

chr7_-_128461313 0.640 ENSMUST00000165023.1
Tial1
Tia1 cytotoxic granule-associated RNA binding protein-like 1
chr6_+_51470339 0.637 ENSMUST00000094623.3
Cbx3
chromobox 3
chr2_-_77946180 0.636 ENSMUST00000111824.1
ENSMUST00000111819.1
ENSMUST00000128963.1
Cwc22


CWC22 spliceosome-associated protein homolog (S. cerevisiae)


chr11_-_109472611 0.615 ENSMUST00000168740.1
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr13_+_51651697 0.607 ENSMUST00000040117.8
ENSMUST00000110044.1
Secisbp2

SECIS binding protein 2

chr11_-_106216318 0.596 ENSMUST00000002043.3
Ccdc47
coiled-coil domain containing 47
chr4_+_84884276 0.590 ENSMUST00000047023.6
Cntln
centlein, centrosomal protein
chr4_-_149307506 0.583 ENSMUST00000055647.8
ENSMUST00000030806.5
ENSMUST00000060537.6
Kif1b


kinesin family member 1B


chr7_-_128461327 0.579 ENSMUST00000033135.7
Tial1
Tia1 cytotoxic granule-associated RNA binding protein-like 1
chr2_+_53192067 0.579 ENSMUST00000028336.6
Arl6ip6
ADP-ribosylation factor-like 6 interacting protein 6
chr5_+_86804214 0.576 ENSMUST00000119339.1
ENSMUST00000120498.1
Ythdc1

YTH domain containing 1

chr2_-_77946375 0.554 ENSMUST00000065889.3
Cwc22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr9_+_46012822 0.542 ENSMUST00000120463.2
ENSMUST00000120247.1
Sik3

SIK family kinase 3

chr13_-_17805093 0.526 ENSMUST00000042365.7
Cdk13
cyclin-dependent kinase 13
chr13_-_9765137 0.507 ENSMUST00000062658.8
ENSMUST00000130151.1
ENSMUST00000110636.1
ENSMUST00000152725.1
Zmynd11



zinc finger, MYND domain containing 11



chr10_-_128176568 0.503 ENSMUST00000092033.2
Rbms2
RNA binding motif, single stranded interacting protein 2
chr7_+_127841752 0.495 ENSMUST00000033075.7
Stx4a
syntaxin 4A (placental)
chr9_+_46012810 0.492 ENSMUST00000126865.1
Sik3
SIK family kinase 3
chr6_-_70792155 0.481 ENSMUST00000066134.5
Rpia
ribose 5-phosphate isomerase A
chr9_+_110132015 0.476 ENSMUST00000088716.5
ENSMUST00000111969.1
ENSMUST00000035057.7
ENSMUST00000111966.1
ENSMUST00000111968.1
Smarcc1




SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1




chr9_-_64172879 0.476 ENSMUST00000176299.1
ENSMUST00000130127.1
ENSMUST00000176794.1
ENSMUST00000177045.1
Zwilch



zwilch kinetochore protein



chr16_+_55973881 0.476 ENSMUST00000050248.8
Rpl24
ribosomal protein L24
chr11_-_6444352 0.474 ENSMUST00000093346.5
ENSMUST00000109737.2
H2afv

H2A histone family, member V

chr1_+_175880775 0.464 ENSMUST00000039725.6
Exo1
exonuclease 1
chr2_-_18998126 0.463 ENSMUST00000006912.5
Pip4k2a
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr4_+_84884418 0.460 ENSMUST00000169371.2
Cntln
centlein, centrosomal protein
chr7_+_4137032 0.459 ENSMUST00000128756.1
ENSMUST00000132086.1
ENSMUST00000037472.6
ENSMUST00000117274.1
ENSMUST00000121270.1
Leng8




leukocyte receptor cluster (LRC) member 8




chr4_+_130107556 0.452 ENSMUST00000030563.5
Pef1
penta-EF hand domain containing 1
chr3_-_144570136 0.451 ENSMUST00000043325.7
Hs2st1
heparan sulfate 2-O-sulfotransferase 1
chrX_+_13280970 0.448 ENSMUST00000000804.6
Ddx3x
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked
chr12_-_56345862 0.446 ENSMUST00000021416.7
Mbip
MAP3K12 binding inhibitory protein 1
chr2_-_36136773 0.439 ENSMUST00000028251.3
Rbm18
RNA binding motif protein 18
chr12_+_17348422 0.432 ENSMUST00000046011.10
Nol10
nucleolar protein 10
chr15_-_99651580 0.426 ENSMUST00000171908.1
ENSMUST00000171702.1
ENSMUST00000109581.2
ENSMUST00000169810.1
ENSMUST00000023756.5
Racgap1




Rac GTPase-activating protein 1




chr1_-_46854046 0.413 ENSMUST00000027131.4
Slc39a10
solute carrier family 39 (zinc transporter), member 10
chr1_-_91459254 0.404 ENSMUST00000069620.8
Per2
period circadian clock 2
chr6_-_51469836 0.396 ENSMUST00000090002.7
Hnrnpa2b1
heterogeneous nuclear ribonucleoprotein A2/B1
chr12_+_105784694 0.395 ENSMUST00000109901.2
ENSMUST00000168186.1
ENSMUST00000163473.1
ENSMUST00000170540.1
ENSMUST00000166735.1
ENSMUST00000170002.1
Papola





poly (A) polymerase alpha





chr7_-_128461630 0.377 ENSMUST00000106226.2
Tial1
Tia1 cytotoxic granule-associated RNA binding protein-like 1
chr2_+_162931520 0.370 ENSMUST00000130411.1
Srsf6
serine/arginine-rich splicing factor 6
chr6_-_51469869 0.368 ENSMUST00000114459.1
ENSMUST00000069949.6
Hnrnpa2b1

heterogeneous nuclear ribonucleoprotein A2/B1

chrX_+_134601271 0.366 ENSMUST00000050331.6
ENSMUST00000059297.5
Hnrnph2

heterogeneous nuclear ribonucleoprotein H2

chrX_+_134601179 0.357 ENSMUST00000074950.4
ENSMUST00000113203.1
ENSMUST00000113202.1
Hnrnph2


heterogeneous nuclear ribonucleoprotein H2


chr12_+_73964481 0.354 ENSMUST00000021532.4
Snapc1
small nuclear RNA activating complex, polypeptide 1
chr7_+_102441685 0.353 ENSMUST00000033283.9
Rrm1
ribonucleotide reductase M1
chr3_+_144570687 0.341 ENSMUST00000106211.1
Sep15
selenoprotein
chr9_+_59291565 0.340 ENSMUST00000026266.7
Adpgk
ADP-dependent glucokinase
chr12_+_33429605 0.340 ENSMUST00000020877.7
Twistnb
TWIST neighbor
chr13_-_9764865 0.336 ENSMUST00000128658.1
Zmynd11
zinc finger, MYND domain containing 11
chr1_+_143739016 0.315 ENSMUST00000145969.1
Glrx2
glutaredoxin 2 (thioltransferase)
chr7_+_66109474 0.314 ENSMUST00000036372.6
Chsy1
chondroitin sulfate synthase 1
chr12_+_110850273 0.307 ENSMUST00000170060.2
Zfp839
zinc finger protein 839
chr16_-_87432597 0.299 ENSMUST00000039449.7
Ltn1
listerin E3 ubiquitin protein ligase 1
chr1_-_55088156 0.270 ENSMUST00000127861.1
ENSMUST00000144077.1
Hspd1

heat shock protein 1 (chaperonin)

chr4_-_129619069 0.266 ENSMUST00000121442.1
ENSMUST00000046675.5
Iqcc

IQ motif containing C

chr10_+_42583787 0.265 ENSMUST00000105497.1
ENSMUST00000144806.1
Ostm1

osteopetrosis associated transmembrane protein 1

chr5_-_145201829 0.259 ENSMUST00000162220.1
ENSMUST00000031632.8
Zkscan14

zinc finger with KRAB and SCAN domains 14

chr10_-_127121125 0.256 ENSMUST00000164259.1
ENSMUST00000080975.4
Os9

amplified in osteosarcoma

chr12_-_31654767 0.250 ENSMUST00000020977.2
Dus4l
dihydrouridine synthase 4-like (S. cerevisiae)
chr1_+_156035705 0.245 ENSMUST00000111754.2
ENSMUST00000133152.1
Tor1aip2

torsin A interacting protein 2

chr13_-_49652714 0.223 ENSMUST00000021818.7
Cenpp
centromere protein P
chr9_+_44066993 0.218 ENSMUST00000034508.7
Usp2
ubiquitin specific peptidase 2
chr8_+_95320440 0.218 ENSMUST00000162294.1
Tepp
testis, prostate and placenta expressed
chr14_+_57424054 0.211 ENSMUST00000122063.1
Ift88
intraflagellar transport 88
chr16_-_55838827 0.209 ENSMUST00000096026.2
ENSMUST00000036273.6
ENSMUST00000114457.1
Nfkbiz


nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta


chr4_-_4138817 0.203 ENSMUST00000133567.1
Penk
preproenkephalin
chr3_+_144570409 0.200 ENSMUST00000082437.3
Sep15
selenoprotein
chr18_-_3337539 0.188 ENSMUST00000142690.1
ENSMUST00000025069.4
ENSMUST00000082141.5
ENSMUST00000165086.1
ENSMUST00000149803.1
Crem




cAMP responsive element modulator




chr5_+_142629537 0.171 ENSMUST00000036872.9
ENSMUST00000110778.1
Wipi2

WD repeat domain, phosphoinositide interacting 2

chr17_+_35001282 0.171 ENSMUST00000174260.1
Vars
valyl-tRNA synthetase
chr17_+_85090647 0.167 ENSMUST00000095188.5
Camkmt
calmodulin-lysine N-methyltransferase
chr19_-_40588453 0.165 ENSMUST00000025979.6
Aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr4_-_4138432 0.161 ENSMUST00000070375.7
Penk
preproenkephalin
chr18_-_43477764 0.160 ENSMUST00000057110.9
Eif3j2
eukaryotic translation initiation factor 3, subunit J2
chr11_-_85139939 0.157 ENSMUST00000108075.2
Usp32
ubiquitin specific peptidase 32
chr19_-_3282958 0.151 ENSMUST00000119292.1
ENSMUST00000025751.3
Ighmbp2

immunoglobulin mu binding protein 2

chr19_-_40588338 0.141 ENSMUST00000176939.1
Aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr4_+_40970906 0.130 ENSMUST00000098143.4
ENSMUST00000030133.8
ENSMUST00000091614.6
Nfx1


nuclear transcription factor, X-box binding 1


chr11_-_118248507 0.122 ENSMUST00000017276.7
Cyth1
cytohesin 1
chr1_-_55088024 0.122 ENSMUST00000027123.8
Hspd1
heat shock protein 1 (chaperonin)
chr4_+_84884366 0.113 ENSMUST00000102819.3
Cntln
centlein, centrosomal protein
chr7_-_55962424 0.103 ENSMUST00000126604.1
ENSMUST00000117812.1
ENSMUST00000119201.1
Nipa2


non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human)


chr11_-_93885752 0.103 ENSMUST00000066888.3
Utp18
UTP18, small subunit (SSU) processome component, homolog (yeast)
chr7_-_111082997 0.100 ENSMUST00000161051.1
ENSMUST00000160132.1
ENSMUST00000106666.3
ENSMUST00000162415.1
Eif4g2



eukaryotic translation initiation factor 4, gamma 2



chr16_+_20548577 0.099 ENSMUST00000003319.5
Abcf3
ATP-binding cassette, sub-family F (GCN20), member 3
chr14_-_20702991 0.098 ENSMUST00000180987.1
6230400D17Rik
RIKEN cDNA 6230400D17 gene
chrX_+_139480365 0.097 ENSMUST00000046763.6
ENSMUST00000113030.2
D330045A20Rik

RIKEN cDNA D330045A20 gene

chr2_-_109280718 0.083 ENSMUST00000147770.1
Mettl15
methyltransferase like 15
chr5_+_29378604 0.078 ENSMUST00000181005.1
4632411P08Rik
RIKEN cDNA 4632411P08 gene
chr9_+_44067072 0.077 ENSMUST00000177054.1
Usp2
ubiquitin specific peptidase 2
chrX_+_7842056 0.072 ENSMUST00000115667.3
ENSMUST00000115668.3
ENSMUST00000115665.1
Otud5


OTU domain containing 5


chr15_-_100425050 0.070 ENSMUST00000123461.1
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr19_-_40588374 0.068 ENSMUST00000175932.1
ENSMUST00000176955.1
ENSMUST00000149476.2
Aldh18a1


aldehyde dehydrogenase 18 family, member A1


chr9_+_108347827 0.060 ENSMUST00000035237.6
Usp4
ubiquitin specific peptidase 4 (proto-oncogene)
chr4_-_62408618 0.052 ENSMUST00000107459.1
ENSMUST00000084525.5
Cdc26

cell division cycle 26

chr3_-_97767916 0.050 ENSMUST00000045243.8
Pde4dip
phosphodiesterase 4D interacting protein (myomegalin)
chr19_-_4615453 0.047 ENSMUST00000053597.2
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr9_+_37208291 0.043 ENSMUST00000034632.8
Tmem218
transmembrane protein 218
chr11_-_116024489 0.039 ENSMUST00000016703.7
H3f3b
H3 histone, family 3B
chr5_-_36695969 0.034 ENSMUST00000031091.9
ENSMUST00000140063.1
D5Ertd579e

DNA segment, Chr 5, ERATO Doi 579, expressed

chr5_+_136987019 0.025 ENSMUST00000004968.4
Plod3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr8_+_105701142 0.015 ENSMUST00000098444.2
Pard6a
par-6 (partitioning defective 6,) homolog alpha (C. elegans)
chr6_+_112696772 0.005 ENSMUST00000180959.1
Gm26799
predicted gene, 26799
chr2_+_144556229 0.002 ENSMUST00000143573.1
ENSMUST00000028916.8
ENSMUST00000155258.1
Sec23b


SEC23B (S. cerevisiae)



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.8 3.2 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.6 2.4 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.5 1.6 GO:1901079 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) positive regulation of relaxation of muscle(GO:1901079)
0.4 1.2 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.4 1.2 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.4 1.2 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308) regulation of eosinophil activation(GO:1902566)
0.4 1.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.3 1.6 GO:0021764 amygdala development(GO:0021764)
0.3 1.1 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.3 2.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.3 1.5 GO:0044351 macropinocytosis(GO:0044351)
0.2 0.7 GO:0042939 glutathione transport(GO:0034635) oligopeptide transmembrane transport(GO:0035672) xenobiotic transport(GO:0042908) tripeptide transport(GO:0042939)
0.2 1.7 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.2 2.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.2 0.6 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
0.2 1.1 GO:1903564 regulation of protein localization to cilium(GO:1903564)
0.2 2.7 GO:0010225 response to UV-C(GO:0010225)
0.2 1.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.2 0.5 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.1 3.1 GO:0046033 AMP metabolic process(GO:0046033)
0.1 0.4 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.8 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 0.4 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.1 0.4 GO:0002842 positive regulation of T cell mediated immune response to tumor cell(GO:0002842) protein import into mitochondrial intermembrane space(GO:0045041)
0.1 0.8 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.1 0.4 GO:0006592 ornithine biosynthetic process(GO:0006592)
0.1 1.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 0.7 GO:0072396 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.1 0.5 GO:0006014 D-ribose metabolic process(GO:0006014)
0.1 0.5 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 1.2 GO:1902570 protein localization to nucleolus(GO:1902570)
0.1 0.5 GO:0030202 heparin metabolic process(GO:0030202)
0.1 1.1 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.1 1.5 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.4 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 0.4 GO:0042256 mature ribosome assembly(GO:0042256)
0.1 1.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.4 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 0.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 3.6 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 1.4 GO:0072520 seminiferous tubule development(GO:0072520)
0.1 0.6 GO:0006983 ER overload response(GO:0006983)
0.1 0.2 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.1 0.4 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 1.5 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1 1.1 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 1.1 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 1.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.5 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.5 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 1.3 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.2 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.0 0.2 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.2 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.5 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.5 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 1.0 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.6 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.7 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 1.7 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 1.3 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 1.6 GO:0017145 stem cell division(GO:0017145)
0.0 0.4 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.2 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.3 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 1.1 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.5 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0 0.1 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.0 0.4 GO:0031440 regulation of mRNA 3'-end processing(GO:0031440)
0.0 0.4 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 0.1 GO:0051189 molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.5 0.5 GO:1990423 RZZ complex(GO:1990423)
0.5 1.8 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.3 1.6 GO:0042583 chromaffin granule(GO:0042583)
0.2 1.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2 1.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.2 1.2 GO:0000322 storage vacuole(GO:0000322)
0.1 0.7 GO:0030893 meiotic cohesin complex(GO:0030893)
0.1 2.4 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 1.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 1.2 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 0.4 GO:0032280 symmetric synapse(GO:0032280)
0.1 0.6 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.3 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 0.4 GO:0097149 centralspindlin complex(GO:0097149)
0.1 1.5 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.4 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 3.2 GO:0060170 ciliary membrane(GO:0060170)
0.1 0.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 1.1 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.8 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.5 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.8 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 2.3 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.7 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 1.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.6 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.1 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 2.1 GO:0016363 nuclear matrix(GO:0016363)
0.0 2.6 GO:0055037 recycling endosome(GO:0055037)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.2 GO:0005814 centriole(GO:0005814)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0004994 somatostatin receptor activity(GO:0004994)
1.0 3.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.4 2.3 GO:0042731 PH domain binding(GO:0042731)
0.3 1.2 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.3 3.2 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.2 0.7 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673) sphingolipid transporter activity(GO:0046624)
0.2 1.2 GO:0030284 estrogen receptor activity(GO:0030284)
0.2 1.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.2 0.7 GO:0036033 mediator complex binding(GO:0036033)
0.2 0.5 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.2 0.5 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.1 3.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.8 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.4 GO:0017084 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
0.1 2.7 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.3 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 1.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 2.1 GO:0005521 lamin binding(GO:0005521)
0.1 2.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.6 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 0.8 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.1 0.3 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 1.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.4 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 1.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.4 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 1.0 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.4 GO:0033592 RNA strand annealing activity(GO:0033592)
0.1 1.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 2.4 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 0.7 GO:0005522 profilin binding(GO:0005522)
0.1 0.4 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.4 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.4 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.2 GO:1990955 G-rich single-stranded DNA binding(GO:1990955)
0.0 1.3 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.5 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 1.6 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.2 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 2.8 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.5 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 1.6 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.6 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.3 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.1 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.6 GO:1990939 ATP-dependent microtubule motor activity(GO:1990939)
0.0 1.0 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.5 GO:0031492 nucleosomal DNA binding(GO:0031492)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 2.4 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 2.3 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.1 1.1 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.6 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 0.7 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.0 1.7 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 4.2 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.7 PID_ATM_PATHWAY ATM pathway
0.0 0.3 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.3 PID_E2F_PATHWAY E2F transcription factor network
0.0 1.0 PID_LKB1_PATHWAY LKB1 signaling events
0.0 1.2 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 0.4 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.4 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 REACTOME_INTEGRATION_OF_PROVIRUS Genes involved in Integration of provirus
0.1 2.2 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 1.1 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.8 REACTOME_KINESINS Genes involved in Kinesins
0.1 0.8 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 3.6 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.5 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.4 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.4 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 1.6 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.9 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.7 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.5 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.0 0.5 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.3 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.4 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.4 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.4 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.5 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.5 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis