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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr15_+_18818895	3.455	ENSMUST00000166873.2	Cdh10	cadherin 10
chr5_+_3344194	3.088	ENSMUST00000042410.4	Cdk6	cyclin-dependent kinase 6
chr5_+_3343893	2.936	ENSMUST00000165117.1	Cdk6	cyclin-dependent kinase 6
chr3_-_103737995	2.873	ENSMUST00000029440.8	Olfml3	olfactomedin-like 3
chr2_-_104257400	2.872	ENSMUST00000141159.1	D430041D05Rik	RIKEN cDNA D430041D05 gene
chr8_+_13405080	2.747	ENSMUST00000033827.7	Grk1	G protein-coupled receptor kinase 1
chr7_-_15879844	2.258	ENSMUST00000172758.1 ENSMUST00000044434.6	Crx	cone-rod homeobox containing gene
chr8_-_113848615	2.246	ENSMUST00000093113.4	Adamts18	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18
chr15_-_93595877	2.041	ENSMUST00000048982.4	Prickle1	prickle homolog 1 (Drosophila)
chr1_-_44218952	1.808	ENSMUST00000054801.3	Mettl21e	methyltransferase like 21E
chr1_-_168431896	1.593	ENSMUST00000176540.1	Pbx1	pre B cell leukemia homeobox 1
chr1_-_168431695	1.465	ENSMUST00000176790.1	Pbx1	pre B cell leukemia homeobox 1
chr1_-_168431502	1.425	ENSMUST00000064438.4	Pbx1	pre B cell leukemia homeobox 1
chr2_+_91259822	1.364	ENSMUST00000138470.1	Pacsin3	protein kinase C and casein kinase substrate in neurons 3
chr11_+_70459940	1.262	ENSMUST00000147289.1 ENSMUST00000126105.1	Zmynd15	zinc finger, MYND-type containing 15
chr6_+_136954521	1.126	ENSMUST00000137768.1	Pde6h	phosphodiesterase 6H, cGMP-specific, cone, gamma
chr11_-_52282564	1.087	ENSMUST00000086844.3	Tcf7	transcription factor 7, T cell specific
chr11_-_107337556	1.070	ENSMUST00000040380.6	Pitpnc1	phosphatidylinositol transfer protein, cytoplasmic 1
chr13_+_3361029	1.031	ENSMUST00000179981.1	Gm16505	predicted gene 16505
chr1_+_177444653	1.022	ENSMUST00000094276.3	Zbtb18	zinc finger and BTB domain containing 18
chr10_-_22149270	1.009	ENSMUST00000179054.1 ENSMUST00000069372.6	E030030I06Rik	RIKEN cDNA E030030I06 gene
chr7_-_25398697	1.008	ENSMUST00000105177.2 ENSMUST00000149349.1	Lipe	lipase, hormone sensitive
chr11_+_19924403	0.976	ENSMUST00000093298.5	Spred2	sprouty-related, EVH1 domain containing 2
chr4_+_84884418	0.883	ENSMUST00000169371.2	Cntln	centlein, centrosomal protein
chr12_+_81631369	0.881	ENSMUST00000036116.5	Ttc9	tetratricopeptide repeat domain 9
chr6_+_3993776	0.848	ENSMUST00000031673.5	Gngt1	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr11_+_19924354	0.832	ENSMUST00000093299.6	Spred2	sprouty-related, EVH1 domain containing 2
chr7_-_127725616	0.793	ENSMUST00000076091.2	Ctf2	cardiotrophin 2
chr14_-_118052235	0.783	ENSMUST00000022725.2	Dct	dopachrome tautomerase
chr4_+_102589687	0.663	ENSMUST00000097949.4 ENSMUST00000106901.1	Pde4b	phosphodiesterase 4B, cAMP specific
chr7_+_13398115	0.655	ENSMUST00000005791.7	Cabp5	calcium binding protein 5
chr6_+_4902913	0.637	ENSMUST00000175889.1 ENSMUST00000168998.2	Ppp1r9a	protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr19_+_26605106	0.614	ENSMUST00000025862.7 ENSMUST00000176030.1	Smarca2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr13_-_97747399	0.600	ENSMUST00000144993.1	5330416C01Rik	RIKEN cDNA 5330416C01 gene
chr11_-_70459957	0.580	ENSMUST00000019064.2	Cxcl16	chemokine (C-X-C motif) ligand 16
chr8_+_19682268	0.575	ENSMUST00000153710.1 ENSMUST00000127799.1	Gm6483	predicted gene 6483
chr11_+_78322965	0.533	ENSMUST00000017534.8	Aldoc	aldolase C, fructose-bisphosphate
chr6_-_59426279	0.527	ENSMUST00000051065.4	Gprin3	GPRIN family member 3
chr1_+_12692430	0.477	ENSMUST00000180062.1 ENSMUST00000177608.1	Sulf1	sulfatase 1
chr8_+_78509319	0.462	ENSMUST00000034111.8	Slc10a7	solute carrier family 10 (sodium/bile acid cotransporter family), member 7
chrM_+_7759	0.448	ENSMUST00000082407.1 ENSMUST00000082408.1	mt-Atp8 mt-Atp6	mitochondrially encoded ATP synthase 8 mitochondrially encoded ATP synthase 6
chr1_+_178187721	0.406	ENSMUST00000159284.1	Desi2	desumoylating isopeptidase 2
chr15_-_74734313	0.387	ENSMUST00000023260.3	Lypd2	Ly6/Plaur domain containing 2
chr7_-_80403315	0.377	ENSMUST00000147150.1	Furin	furin (paired basic amino acid cleaving enzyme)
chr7_-_98656530	0.371	ENSMUST00000038359.4	2210018M11Rik	RIKEN cDNA 2210018M11 gene
chr11_+_23256001	0.353	ENSMUST00000020538.6 ENSMUST00000109551.1 ENSMUST00000102870.1 ENSMUST00000102869.1	Xpo1	exportin 1, CRM1 homolog (yeast)
chr10_+_128225830	0.346	ENSMUST00000026455.7	Mip	major intrinsic protein of eye lens fiber
chr9_-_50617228	0.283	ENSMUST00000147671.1 ENSMUST00000145139.1 ENSMUST00000155435.1	AU019823	expressed sequence AU019823
chr2_+_23068168	0.270	ENSMUST00000028121.7 ENSMUST00000114523.2 ENSMUST00000144088.1	Acbd5	acyl-Coenzyme A binding domain containing 5
chr14_-_105177280	0.257	ENSMUST00000100327.3 ENSMUST00000022715.7	Rbm26	RNA binding motif protein 26
chr8_-_60954726	0.256	ENSMUST00000110302.1	Clcn3	chloride channel 3
chr10_+_90576872	0.256	ENSMUST00000182550.1 ENSMUST00000099364.5	Anks1b	ankyrin repeat and sterile alpha motif domain containing 1B
chr1_-_155232710	0.253	ENSMUST00000035914.3	BC034090	cDNA sequence BC034090
chr13_-_97747373	0.249	ENSMUST00000123535.1	5330416C01Rik	RIKEN cDNA 5330416C01 gene
chr10_+_18407658	0.248	ENSMUST00000037341.7	Nhsl1	NHS-like 1
chr10_-_9901079	0.244	ENSMUST00000141722.1	Stxbp5	syntaxin binding protein 5 (tomosyn)
chr5_+_19907502	0.241	ENSMUST00000101558.3	Magi2	membrane associated guanylate kinase, WW and PDZ domain containing 2
chr11_+_23256566	0.221	ENSMUST00000136235.1	Xpo1	exportin 1, CRM1 homolog (yeast)
chr1_+_178187417	0.190	ENSMUST00000161075.1 ENSMUST00000027783.7	Desi2	desumoylating isopeptidase 2
chr13_-_113618549	0.184	ENSMUST00000109241.3	Snx18	sorting nexin 18
chr14_-_19977249	0.180	ENSMUST00000160013.1	Gng2	guanine nucleotide binding protein (G protein), gamma 2
chr5_-_134456702	0.175	ENSMUST00000073161.5 ENSMUST00000171794.2 ENSMUST00000111245.2 ENSMUST00000100654.3 ENSMUST00000167084.2 ENSMUST00000100652.3 ENSMUST00000100650.3 ENSMUST00000074114.5	Gtf2ird1	general transcription factor II I repeat domain-containing 1
chr4_-_141053660	0.171	ENSMUST00000040222.7	Crocc	ciliary rootlet coiled-coil, rootletin
chr5_-_144223516	0.163	ENSMUST00000085701.6	Tecpr1	tectonin beta-propeller repeat containing 1
chr19_+_8617991	0.154	ENSMUST00000010250.2	Slc22a6	solute carrier family 22 (organic anion transporter), member 6
chr17_-_35164891	0.143	ENSMUST00000025253.5	Prrc2a	proline-rich coiled-coil 2A
chr16_-_4213404	0.134	ENSMUST00000023165.6	Crebbp	CREB binding protein
chr11_-_90687572	0.134	ENSMUST00000107869.2 ENSMUST00000154599.1 ENSMUST00000107868.1 ENSMUST00000020849.2	Tom1l1	target of myb1-like 1 (chicken)
chr11_-_5099084	0.115	ENSMUST00000063232.6	Ewsr1	Ewing sarcoma breakpoint region 1
chr1_+_44551650	0.106	ENSMUST00000160854.1	Gulp1	GULP, engulfment adaptor PTB domain containing 1
chr5_-_96161990	0.104	ENSMUST00000155901.1	Cnot6l	CCR4-NOT transcription complex, subunit 6-like
chr13_+_75089826	0.095	ENSMUST00000022075.4	Pcsk1	proprotein convertase subtilisin/kexin type 1
chr11_-_68973840	0.083	ENSMUST00000038644.4	Rangrf	RAN guanine nucleotide release factor
chr4_-_141053704	0.075	ENSMUST00000102491.3	Crocc	ciliary rootlet coiled-coil, rootletin
chr14_+_99298652	0.065	ENSMUST00000005279.6	Klf5	Kruppel-like factor 5
chr2_-_30093607	0.051	ENSMUST00000081838.6	Zdhhc12	zinc finger, DHHC domain containing 12
chr16_-_46010212	0.045	ENSMUST00000130481.1	Plcxd2	phosphatidylinositol-specific phospholipase C, X domain containing 2
chr17_+_27655572	0.040	ENSMUST00000045896.3	Pacsin1	protein kinase C and casein kinase substrate in neurons 1
chr10_+_80292453	0.037	ENSMUST00000068408.7 ENSMUST00000062674.6	Rps15	ribosomal protein S15
chrX_+_169879596	0.034	ENSMUST00000112105.1 ENSMUST00000078947.5	Mid1	midline 1
chr2_-_30093642	0.031	ENSMUST00000102865.4	Zdhhc12	zinc finger, DHHC domain containing 12
chr2_-_51972990	0.030	ENSMUST00000145481.1 ENSMUST00000112705.2	Nmi	N-myc (and STAT) interactor
chrX_+_7728439	0.027	ENSMUST00000033489.7	Praf2	PRA1 domain family 2
chr18_-_12305638	0.010	ENSMUST00000122408.1 ENSMUST00000118525.1 ENSMUST00000142066.1	Ankrd29	ankyrin repeat domain 29
chr2_+_91265252	0.007	ENSMUST00000028691.6	Arfgap2	ADP-ribosylation factor GTPase activating protein 2

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	2.7	GO:0016056	photoreceptor cell morphogenesis(GO:0008594) rhodopsin mediated signaling pathway(GO:0016056) post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.9	6.0	GO:0044838	cell quiescence(GO:0044838)
0.7	2.0	GO:0051892	negative regulation of cardioblast differentiation(GO:0051892)
0.3	1.0	GO:0046340	diacylglycerol catabolic process(GO:0046340)
0.2	0.6	GO:1904049	negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.2	2.2	GO:0090331	negative regulation of platelet aggregation(GO:0090331)
0.1	4.5	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.1	1.1	GO:0002681	somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.1	0.8	GO:0006570	tyrosine metabolic process(GO:0006570)
0.1	1.8	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1	0.5	GO:0014846	esophagus smooth muscle contraction(GO:0014846)
0.1	0.4	GO:0090472	dibasic protein processing(GO:0090472)
0.1	0.3	GO:0097401	synaptic vesicle lumen acidification(GO:0097401)
0.1	0.8	GO:0007602	phototransduction(GO:0007602)
0.1	0.6	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
0.1	1.1	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.1	0.6	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
0.1	1.4	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1	0.5	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1	0.2	GO:0015747	urate transport(GO:0015747)
0.1	0.7	GO:1901898	negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0	0.3	GO:0032782	bile acid secretion(GO:0032782)
0.0	0.6	GO:0010818	T cell chemotaxis(GO:0010818)
0.0	1.1	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.0	3.5	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.3	GO:0030242	pexophagy(GO:0030242)
0.0	0.2	GO:0036089	cleavage furrow formation(GO:0036089)
0.0	0.2	GO:0014886	transition between slow and fast fiber(GO:0014886)
0.0	0.2	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0	0.1	GO:0045358	negative regulation of interferon-beta biosynthetic process(GO:0045358)
0.0	2.3	GO:0007601	visual perception(GO:0007601)
0.0	0.2	GO:0097475	motor neuron migration(GO:0097475)
0.0	0.3	GO:1900383	regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0	1.0	GO:0010389	regulation of G2/M transition of mitotic cell cycle(GO:0010389)
0.0	0.4	GO:0015985	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0	0.1	GO:0086028	bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.0	1.0	GO:0021766	hippocampus development(GO:0021766)
0.0	0.1	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0	1.3	GO:0007286	spermatid development(GO:0007286)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	GO:1990761	growth cone lamellipodium(GO:1990761)
0.1	7.1	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1	3.6	GO:0001750	photoreceptor outer segment(GO:0001750)
0.1	0.6	GO:0005642	annulate lamellae(GO:0005642)
0.0	0.8	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	0.6	GO:0071564	npBAF complex(GO:0071564)
0.0	0.4	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	1.1	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	4.6	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
0.0	0.2	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0	0.7	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	0.4	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.0	0.2	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.3	GO:0042581	specific granule(GO:0042581)
0.0	1.0	GO:0045171	intercellular bridge(GO:0045171)
0.0	0.3	GO:0005921	gap junction(GO:0005921)
0.0	0.2	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	1.0	GO:0005811	lipid particle(GO:0005811)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.0	6.0	GO:0098770	FBXO family protein binding(GO:0098770)
0.7	2.7	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.3	1.8	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.2	1.0	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.2	2.3	GO:0043522	leucine zipper domain binding(GO:0043522)
0.1	1.4	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.1	1.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.1	0.5	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1	0.5	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.1	0.6	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.1	0.3	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
0.1	1.1	GO:0030553	cGMP binding(GO:0030553)
0.1	0.8	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1	0.6	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.1	0.6	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	2.0	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin binding(GO:0030332)
0.0	0.2	GO:0070699	type II activin receptor binding(GO:0070699)
0.0	0.2	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	0.3	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.4	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	2.2	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.7	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.6	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.1	GO:0043426	MRF binding(GO:0043426)
0.0	0.6	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	0.3	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	1.3	GO:0042826	histone deacetylase binding(GO:0042826)
0.0	1.1	GO:0008013	beta-catenin binding(GO:0008013)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	3.6	PID_RHODOPSIN_PATHWAY	Visual signal transduction: Rods
0.1	6.0	PID_IL2_STAT5_PATHWAY	IL2 signaling events mediated by STAT5
0.1	0.3	PID_CONE_PATHWAY	Visual signal transduction: Cones
0.0	3.8	PID_REG_GR_PATHWAY	Glucocorticoid receptor regulatory network
0.0	0.6	PID_RANBP2_PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	1.8	PID_KIT_PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	2.7	NABA_ECM_REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	1.1	PID_BETA_CATENIN_NUC_PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.6	PID_AR_TF_PATHWAY	Regulation of Androgen receptor activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.8	REACTOME_OLFACTORY_SIGNALING_PATHWAY	Genes involved in Olfactory Signaling Pathway
0.1	6.0	REACTOME_G1_PHASE	Genes involved in G1 Phase
0.1	3.5	REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.6	REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	1.0	REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.3	REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.4	REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.2	REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.6	REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.1	REACTOME_PEPTIDE_HORMONE_BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.0	0.5	REACTOME_GLUCONEOGENESIS	Genes involved in Gluconeogenesis

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