Motif ID: Gsx1_Alx1_Mixl1_Lbx2

Z-value: 0.867


Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gsx1mm10_v2_chr5_+_147188678_147188696-0.501.0e-03Click!
Alx1mm10_v2_chr10_-_103029043_1030290540.105.4e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Gsx1_Alx1_Mixl1_Lbx2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_49757257 8.151 ENSMUST00000035931.7
Pcdh18
protocadherin 18
chr2_+_20737306 6.349 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr5_-_84417359 6.090 ENSMUST00000113401.1
Epha5
Eph receptor A5
chr7_+_103550368 5.836 ENSMUST00000106888.1
Olfr613
olfactory receptor 613
chr5_-_62766153 5.492 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr2_+_116067213 5.425 ENSMUST00000152412.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chr16_+_33684538 4.718 ENSMUST00000126532.1
Heg1
HEG homolog 1 (zebrafish)
chr18_+_57468478 4.704 ENSMUST00000091892.2
Ctxn3
cortexin 3
chrX_+_56454871 4.658 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr9_+_118478182 4.616 ENSMUST00000111763.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr9_+_118478344 4.470 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chr2_-_116067391 4.398 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr1_-_190170671 4.143 ENSMUST00000175916.1
Prox1
prospero-related homeobox 1
chr15_+_25773985 4.133 ENSMUST00000125667.1
Myo10
myosin X
chr13_+_44121167 4.066 ENSMUST00000163056.1
ENSMUST00000159595.1
Gm5083

predicted gene 5083

chr7_+_29071597 3.127 ENSMUST00000180926.1
Gm26604
predicted gene, 26604
chr9_+_96258697 2.988 ENSMUST00000179416.1
Tfdp2
transcription factor Dp 2
chrM_+_11734 2.808 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chr1_-_172027269 2.758 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2

vang-like 2 (van gogh, Drosophila)

chr17_+_45734506 2.655 ENSMUST00000180558.1
F630040K05Rik
RIKEN cDNA F630040K05 gene
chr3_-_66296807 2.571 ENSMUST00000029419.7
Veph1
ventricular zone expressed PH domain-containing 1
chrX_-_74246534 2.561 ENSMUST00000101454.2
ENSMUST00000033699.6
Flna

filamin, alpha

chr16_-_63864114 2.557 ENSMUST00000064405.6
Epha3
Eph receptor A3
chr6_-_126645784 2.533 ENSMUST00000055168.3
Kcna1
potassium voltage-gated channel, shaker-related subfamily, member 1
chr8_+_45658666 2.447 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
Sorbs2


sorbin and SH3 domain containing 2


chr8_+_45658731 2.403 ENSMUST00000143820.1
ENSMUST00000132139.1
Sorbs2

sorbin and SH3 domain containing 2

chr15_+_55307743 2.341 ENSMUST00000023053.5
ENSMUST00000110221.2
ENSMUST00000110217.3
Col14a1


collagen, type XIV, alpha 1


chr8_+_23411490 2.245 ENSMUST00000033952.7
Sfrp1
secreted frizzled-related protein 1
chrM_+_10167 2.208 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr1_-_172027251 2.195 ENSMUST00000138714.1
Vangl2
vang-like 2 (van gogh, Drosophila)
chr7_+_51879041 2.124 ENSMUST00000107591.2
Gas2
growth arrest specific 2
chr7_+_82337218 2.058 ENSMUST00000173828.1
Adamtsl3
ADAMTS-like 3
chr4_-_155056784 2.055 ENSMUST00000131173.2
Plch2
phospholipase C, eta 2
chrX_-_102157065 2.039 ENSMUST00000056904.2
Ercc6l
excision repair cross-complementing rodent repair deficiency complementation group 6 like
chr5_+_17574726 2.008 ENSMUST00000169603.1
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chrM_+_7005 1.956 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr8_-_61902669 1.929 ENSMUST00000121785.1
ENSMUST00000034057.7
Palld

palladin, cytoskeletal associated protein

chrM_+_9870 1.928 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr7_+_64185459 1.921 ENSMUST00000177102.2
ENSMUST00000107519.1
ENSMUST00000137650.1
ENSMUST00000032737.5
ENSMUST00000107515.1
ENSMUST00000144996.1
Trpm1





transient receptor potential cation channel, subfamily M, member 1





chr8_-_120228221 1.905 ENSMUST00000183235.1
A330074K22Rik
RIKEN cDNA A330074K22 gene
chr11_+_29373618 1.869 ENSMUST00000040182.6
ENSMUST00000109477.1
Ccdc88a

coiled coil domain containing 88A

chr14_+_53324632 1.852 ENSMUST00000178100.1
Trav7n-6
T cell receptor alpha variable 7N-6
chrX_+_159697308 1.753 ENSMUST00000123433.1
Sh3kbp1
SH3-domain kinase binding protein 1
chr9_+_65890237 1.718 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr5_+_15516489 1.663 ENSMUST00000178227.1
Gm21847
predicted gene, 21847
chr7_+_123123870 1.577 ENSMUST00000094053.5
Tnrc6a
trinucleotide repeat containing 6a
chr17_-_48432723 1.560 ENSMUST00000046549.3
Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr2_+_25372315 1.549 ENSMUST00000028329.6
ENSMUST00000114293.2
ENSMUST00000100323.2
Sapcd2


suppressor APC domain containing 2


chr3_-_88410295 1.523 ENSMUST00000056370.7
Pmf1
polyamine-modulated factor 1
chr1_+_170308802 1.489 ENSMUST00000056991.5
1700015E13Rik
RIKEN cDNA 1700015E13 gene
chr17_+_17402672 1.463 ENSMUST00000115576.2
Lix1
limb expression 1 homolog (chicken)
chr6_+_37870786 1.451 ENSMUST00000120428.1
ENSMUST00000031859.7
Trim24

tripartite motif-containing 24

chr12_-_111813834 1.405 ENSMUST00000021715.5
Xrcc3
X-ray repair complementing defective repair in Chinese hamster cells 3
chr1_-_24612700 1.389 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chr3_+_32436151 1.387 ENSMUST00000029201.7
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr1_-_163725123 1.377 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr4_+_108719649 1.363 ENSMUST00000178992.1
3110021N24Rik
RIKEN cDNA 3110021N24 gene
chr4_-_24430838 1.362 ENSMUST00000183964.1
RP23-35K5.2
RP23-35K5.2
chr3_-_157925056 1.341 ENSMUST00000118539.1
Cth
cystathionase (cystathionine gamma-lyase)
chr7_+_51880312 1.338 ENSMUST00000145049.1
Gas2
growth arrest specific 2
chr14_+_79515618 1.332 ENSMUST00000110835.1
Elf1
E74-like factor 1
chrM_+_2743 1.300 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr6_+_134929118 1.240 ENSMUST00000185152.1
ENSMUST00000184504.1
RP23-45G16.5

RP23-45G16.5

chr17_-_35697971 1.230 ENSMUST00000146472.1
Ddr1
discoidin domain receptor family, member 1
chr16_-_97170707 1.228 ENSMUST00000056102.7
Dscam
Down syndrome cell adhesion molecule
chr5_+_17574268 1.228 ENSMUST00000030568.7
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr5_+_13398688 1.228 ENSMUST00000125629.1
Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr14_+_124005355 1.216 ENSMUST00000166105.1
Gm17615
predicted gene, 17615
chr11_-_107337556 1.181 ENSMUST00000040380.6
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr4_-_45532470 1.181 ENSMUST00000147448.1
Shb
src homology 2 domain-containing transforming protein B
chr16_+_33684460 1.153 ENSMUST00000152782.1
ENSMUST00000179453.1
Heg1

HEG homolog 1 (zebrafish)

chr5_-_62765618 1.129 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chrX_-_37110257 1.100 ENSMUST00000076265.6
Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr12_+_49401277 1.086 ENSMUST00000056234.3
Gm9804
predicted gene 9804
chr5_+_138187485 1.068 ENSMUST00000110934.2
Cnpy4
canopy 4 homolog (zebrafish)
chr1_+_19103022 1.044 ENSMUST00000037294.7
Tfap2d
transcription factor AP-2, delta
chr2_-_121235689 1.024 ENSMUST00000142400.1
Trp53bp1
transformation related protein 53 binding protein 1
chr9_-_55919605 1.000 ENSMUST00000037408.8
Scaper
S phase cyclin A-associated protein in the ER
chr13_-_97747399 0.999 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chrX_-_143933204 0.986 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr6_-_57535422 0.985 ENSMUST00000042766.3
Ppm1k
protein phosphatase 1K (PP2C domain containing)
chr2_-_37359274 0.967 ENSMUST00000009174.8
Pdcl
phosducin-like
chr7_-_116031047 0.955 ENSMUST00000106612.1
Sox6
SRY-box containing gene 6
chr1_+_6487231 0.948 ENSMUST00000140079.1
ENSMUST00000131494.1
St18

suppression of tumorigenicity 18

chr4_-_87806276 0.938 ENSMUST00000148059.1
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr2_-_146511899 0.934 ENSMUST00000131824.1
Ralgapa2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr11_+_95337012 0.933 ENSMUST00000037502.6
Fam117a
family with sequence similarity 117, member A
chr7_-_115846080 0.921 ENSMUST00000166207.1
Sox6
SRY-box containing gene 6
chr16_+_43503607 0.909 ENSMUST00000126100.1
ENSMUST00000123047.1
ENSMUST00000156981.1
Zbtb20


zinc finger and BTB domain containing 20


chr11_+_23306884 0.904 ENSMUST00000180046.1
Usp34
ubiquitin specific peptidase 34
chr12_-_83487708 0.904 ENSMUST00000177959.1
ENSMUST00000178756.1
Dpf3

D4, zinc and double PHD fingers, family 3

chr7_-_37772868 0.904 ENSMUST00000176205.1
Zfp536
zinc finger protein 536
chr4_-_87806296 0.901 ENSMUST00000126353.1
ENSMUST00000149357.1
Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr1_-_72284248 0.892 ENSMUST00000097698.4
ENSMUST00000027381.6
Pecr

peroxisomal trans-2-enoyl-CoA reductase

chr15_+_25742314 0.891 ENSMUST00000135981.1
Myo10
myosin X
chr2_-_45112890 0.891 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chr11_+_60537978 0.889 ENSMUST00000044250.3
Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chr4_-_109665249 0.872 ENSMUST00000063531.4
Cdkn2c
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chrM_-_14060 0.863 ENSMUST00000082419.1
mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr9_+_35423582 0.853 ENSMUST00000154652.1
Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chr14_-_100149764 0.845 ENSMUST00000097079.4
Klf12
Kruppel-like factor 12
chr11_-_87359011 0.843 ENSMUST00000055438.4
Ppm1e
protein phosphatase 1E (PP2C domain containing)
chr1_-_155417394 0.826 ENSMUST00000111775.1
ENSMUST00000111774.1
Xpr1

xenotropic and polytropic retrovirus receptor 1

chr4_+_8690399 0.825 ENSMUST00000127476.1
Chd7
chromodomain helicase DNA binding protein 7
chr11_+_23306910 0.821 ENSMUST00000137823.1
Usp34
ubiquitin specific peptidase 34
chr5_-_107875035 0.801 ENSMUST00000138111.1
ENSMUST00000112642.1
Evi5

ecotropic viral integration site 5

chr2_+_181767283 0.801 ENSMUST00000108757.2
Myt1
myelin transcription factor 1
chr9_-_96719549 0.796 ENSMUST00000128269.1
Zbtb38
zinc finger and BTB domain containing 38
chr14_+_80000292 0.795 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr3_+_32436376 0.794 ENSMUST00000108242.1
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr9_-_96719404 0.793 ENSMUST00000140121.1
Zbtb38
zinc finger and BTB domain containing 38
chr2_-_79456750 0.771 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chr6_+_11926758 0.770 ENSMUST00000133776.1
Phf14
PHD finger protein 14
chr9_-_105521147 0.769 ENSMUST00000176770.1
ENSMUST00000085133.6
Atp2c1

ATPase, Ca++-sequestering

chr10_+_39612934 0.768 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chrM_+_7759 0.766 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr2_+_23069210 0.765 ENSMUST00000155602.1
Acbd5
acyl-Coenzyme A binding domain containing 5
chr14_-_12345847 0.765 ENSMUST00000022262.4
Fezf2
Fez family zinc finger 2
chr2_+_181767040 0.758 ENSMUST00000108756.1
Myt1
myelin transcription factor 1
chr9_+_88581036 0.745 ENSMUST00000164661.2
Trim43a
tripartite motif-containing 43A
chrX_-_60893430 0.739 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chrX_-_157415286 0.736 ENSMUST00000079945.4
ENSMUST00000138396.1
Phex

phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)

chr8_+_45627709 0.732 ENSMUST00000134321.1
ENSMUST00000135336.1
Sorbs2

sorbin and SH3 domain containing 2

chr13_-_83729544 0.728 ENSMUST00000181705.1
Gm26803
predicted gene, 26803
chr10_-_76110956 0.724 ENSMUST00000120757.1
Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr18_+_52767994 0.715 ENSMUST00000025413.7
ENSMUST00000163742.2
ENSMUST00000178011.1
Sncaip


synuclein, alpha interacting protein (synphilin)


chr15_+_36179299 0.711 ENSMUST00000047348.3
Spag1
sperm associated antigen 1
chr13_-_27582168 0.702 ENSMUST00000006664.1
ENSMUST00000095926.1
Prl8a1

prolactin family 8, subfamily a, member 1

chr11_-_26591729 0.702 ENSMUST00000109504.1
Vrk2
vaccinia related kinase 2
chr3_-_36571952 0.693 ENSMUST00000029270.3
Ccna2
cyclin A2
chr13_-_97747373 0.693 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr4_-_154636831 0.687 ENSMUST00000030902.6
ENSMUST00000105637.1
ENSMUST00000070313.7
ENSMUST00000105636.1
ENSMUST00000105638.2
ENSMUST00000097759.2
ENSMUST00000124771.1
Prdm16






PR domain containing 16






chr3_+_94398517 0.685 ENSMUST00000050975.3
Lingo4
leucine rich repeat and Ig domain containing 4
chr4_-_45489794 0.685 ENSMUST00000146236.1
Shb
src homology 2 domain-containing transforming protein B
chr2_+_69897220 0.682 ENSMUST00000055758.9
ENSMUST00000112251.2
Ubr3

ubiquitin protein ligase E3 component n-recognin 3

chr5_+_34999046 0.668 ENSMUST00000114281.1
Rgs12
regulator of G-protein signaling 12
chrX_-_143933089 0.654 ENSMUST00000087313.3
Dcx
doublecortin
chr5_-_20882072 0.653 ENSMUST00000118174.1
Phtf2
putative homeodomain transcription factor 2
chr2_+_125068118 0.651 ENSMUST00000070353.3
Slc24a5
solute carrier family 24, member 5
chrX_+_134308084 0.650 ENSMUST00000081064.5
ENSMUST00000101251.1
ENSMUST00000129782.1
Cenpi


centromere protein I


chr5_-_131616599 0.644 ENSMUST00000161804.1
Auts2
autism susceptibility candidate 2
chrX_-_74246364 0.637 ENSMUST00000130007.1
Flna
filamin, alpha
chr3_-_90243073 0.616 ENSMUST00000107369.1
Creb3l4
cAMP responsive element binding protein 3-like 4
chr2_+_69897255 0.613 ENSMUST00000131553.1
Ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr2_-_146511992 0.610 ENSMUST00000109986.2
Ralgapa2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr9_+_113930934 0.608 ENSMUST00000084885.5
ENSMUST00000009885.7
Ubp1

upstream binding protein 1

chr12_+_52516077 0.603 ENSMUST00000110725.1
Arhgap5
Rho GTPase activating protein 5
chrX_+_103356464 0.601 ENSMUST00000116547.2
Chic1
cysteine-rich hydrophobic domain 1
chr5_+_34999111 0.590 ENSMUST00000114283.1
Rgs12
regulator of G-protein signaling 12
chr17_-_51826562 0.589 ENSMUST00000024720.4
ENSMUST00000129667.1
ENSMUST00000156051.1
ENSMUST00000169480.1
ENSMUST00000148559.1
Satb1




special AT-rich sequence binding protein 1




chrX_+_9885622 0.585 ENSMUST00000067529.2
ENSMUST00000086165.3
Sytl5

synaptotagmin-like 5

chr2_-_36136773 0.552 ENSMUST00000028251.3
Rbm18
RNA binding motif protein 18
chr13_-_103764502 0.547 ENSMUST00000074616.5
Srek1
splicing regulatory glutamine/lysine-rich protein 1
chr13_+_23544052 0.541 ENSMUST00000075558.2
Hist1h3f
histone cluster 1, H3f
chr10_+_18407658 0.534 ENSMUST00000037341.7
Nhsl1
NHS-like 1
chr5_+_34999070 0.530 ENSMUST00000114280.1
Rgs12
regulator of G-protein signaling 12
chr2_+_29060239 0.528 ENSMUST00000100237.3
Ttf1
transcription termination factor, RNA polymerase I
chr12_+_111039334 0.526 ENSMUST00000084968.7
Rcor1
REST corepressor 1
chr13_-_78196373 0.525 ENSMUST00000125176.2
Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr16_-_74411292 0.507 ENSMUST00000117200.1
Robo2
roundabout homolog 2 (Drosophila)
chr11_+_82781108 0.500 ENSMUST00000092849.5
ENSMUST00000021039.5
ENSMUST00000080461.5
ENSMUST00000173347.1
ENSMUST00000173727.1
ENSMUST00000173009.1
ENSMUST00000131537.2
ENSMUST00000173722.1
Lig3







ligase III, DNA, ATP-dependent







chr3_+_76593550 0.499 ENSMUST00000162471.1
Fstl5
follistatin-like 5
chr3_-_79628660 0.496 ENSMUST00000120992.1
Etfdh
electron transferring flavoprotein, dehydrogenase
chr1_+_10056922 0.488 ENSMUST00000149214.1
Cspp1
centrosome and spindle pole associated protein 1
chr17_+_7170101 0.486 ENSMUST00000024575.6
Rps6ka2
ribosomal protein S6 kinase, polypeptide 2
chr15_-_50890041 0.484 ENSMUST00000077935.5
Trps1
trichorhinophalangeal syndrome I (human)
chr3_+_76075583 0.480 ENSMUST00000160261.1
Fstl5
follistatin-like 5
chr4_+_98923810 0.479 ENSMUST00000030289.2
Usp1
ubiquitin specific peptidase 1
chr9_-_22208546 0.471 ENSMUST00000167359.1
1810064F22Rik
RIKEN cDNA 1810064F22 gene
chr9_+_113812547 0.470 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
Clasp2


CLIP associating protein 2


chr7_+_67647405 0.467 ENSMUST00000032774.8
ENSMUST00000107471.1
Ttc23

tetratricopeptide repeat domain 23

chrX_+_16619698 0.462 ENSMUST00000026013.5
Maoa
monoamine oxidase A
chr6_+_143285988 0.458 ENSMUST00000160951.1
D6Ertd474e
DNA segment, Chr 6, ERATO Doi 474, expressed
chr1_+_153751859 0.449 ENSMUST00000182538.1
Rnasel
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr16_+_14705832 0.448 ENSMUST00000023356.6
Snai2
snail homolog 2 (Drosophila)
chr15_-_42676967 0.446 ENSMUST00000022921.5
Angpt1
angiopoietin 1
chr12_+_72441852 0.445 ENSMUST00000162159.1
Lrrc9
leucine rich repeat containing 9
chr4_+_98923845 0.444 ENSMUST00000091358.4
Usp1
ubiquitin specific peptidase 1
chr2_+_144527718 0.444 ENSMUST00000028914.2
ENSMUST00000110017.2
Polr3f

polymerase (RNA) III (DNA directed) polypeptide F

chrX_-_133981765 0.443 ENSMUST00000113297.2
ENSMUST00000174542.1
ENSMUST00000033608.8
ENSMUST00000113294.1
Sytl4



synaptotagmin-like 4



chr16_-_10543028 0.442 ENSMUST00000184863.1
ENSMUST00000038281.5
Dexi

dexamethasone-induced transcript

chr17_-_48451510 0.431 ENSMUST00000024794.5
Tspo2
translocator protein 2
chr17_+_50698525 0.425 ENSMUST00000061681.7
Gm7334
predicted gene 7334
chr8_-_67818284 0.423 ENSMUST00000120071.1
Psd3
pleckstrin and Sec7 domain containing 3
chr12_+_55089202 0.423 ENSMUST00000021407.10
Srp54a
signal recognition particle 54A
chr15_+_18818895 0.422 ENSMUST00000166873.2
Cdh10
cadherin 10
chr17_+_25188380 0.420 ENSMUST00000039734.5
Unkl
unkempt-like (Drosophila)
chr17_-_47834682 0.418 ENSMUST00000066368.6
Mdfi
MyoD family inhibitor
chr1_+_93512079 0.417 ENSMUST00000120301.1
ENSMUST00000041983.4
ENSMUST00000122402.1
Farp2


FERM, RhoGEF and pleckstrin domain protein 2


chr16_-_36874806 0.413 ENSMUST00000075946.5
Eaf2
ELL associated factor 2
chr14_+_26579535 0.410 ENSMUST00000037585.7
Dennd6a
DENN/MADD domain containing 6A
chr5_+_135106881 0.405 ENSMUST00000005507.3
Mlxipl
MLX interacting protein-like
chr3_-_146495115 0.405 ENSMUST00000093951.2
Spata1
spermatogenesis associated 1
chr5_+_92137896 0.401 ENSMUST00000031355.6
Uso1
USO1 vesicle docking factor
chr2_-_52335134 0.400 ENSMUST00000075301.3
Neb
nebulin
chr15_+_102406143 0.394 ENSMUST00000170884.1
ENSMUST00000165924.1
ENSMUST00000163709.1
ENSMUST00000001326.6
Sp1



trans-acting transcription factor 1



chr7_+_43690418 0.393 ENSMUST00000056329.6
Klk14
kallikrein related-peptidase 14
chr8_+_106059562 0.389 ENSMUST00000109308.1
Nfatc3
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3
chr12_+_52699297 0.388 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr17_-_29007925 0.385 ENSMUST00000009138.5
ENSMUST00000119274.1
Stk38

serine/threonine kinase 38


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 9.1 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
2.0 5.9 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
1.7 5.0 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
1.4 4.1 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
1.1 3.2 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.9 8.6 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.8 2.5 GO:0050975 sensory perception of touch(GO:0050975)
0.7 2.2 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.7 2.2 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.6 4.5 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.5 1.6 GO:0016554 cytidine to uridine editing(GO:0016554)
0.5 1.5 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.4 1.3 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.4 1.2 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.4 8.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.4 1.9 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.4 1.8 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.3 1.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.3 1.9 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.3 1.5 GO:0060178 regulation of exocyst localization(GO:0060178)
0.3 0.8 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.3 1.6 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.3 0.8 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.2 0.2 GO:0003162 atrioventricular node development(GO:0003162)
0.2 0.7 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.2 0.9 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.2 0.6 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.2 1.0 GO:0030901 midbrain development(GO:0030901)
0.2 1.9 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.2 0.8 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.2 1.1 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.2 1.9 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.2 8.4 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2 6.0 GO:0007608 sensory perception of smell(GO:0007608)
0.2 0.5 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.2 0.7 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.2 0.5 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.2 0.8 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.4 GO:0030210 heparin biosynthetic process(GO:0030210) Tie signaling pathway(GO:0048014)
0.1 1.9 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.7 GO:1904659 glucose transmembrane transport(GO:1904659)
0.1 8.6 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.1 1.6 GO:0060539 diaphragm development(GO:0060539)
0.1 0.8 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) phosphate ion transmembrane transport(GO:0035435) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.4 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.1 0.4 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.1 0.4 GO:0048818 embryonic nail plate morphogenesis(GO:0035880) positive regulation of hair follicle maturation(GO:0048818) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364)
0.1 1.6 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.6 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.1 0.5 GO:0042420 dopamine catabolic process(GO:0042420)
0.1 0.3 GO:0036233 glycine import(GO:0036233)
0.1 1.8 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.3 GO:1903546 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to photoreceptor outer segment(GO:1903546)
0.1 1.9 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.9 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.1 1.7 GO:0010715 regulation of extracellular matrix disassembly(GO:0010715)
0.1 1.6 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.4 GO:0070814 hydrogen sulfide biosynthetic process(GO:0070814)
0.1 0.3 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.4 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.5 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361) termination of RNA polymerase I transcription(GO:0006363)
0.1 0.6 GO:0030242 pexophagy(GO:0030242)
0.1 0.7 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 0.9 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.1 0.5 GO:0090298 negative regulation of mitochondrial DNA replication(GO:0090298)
0.1 0.2 GO:0043622 cortical microtubule organization(GO:0043622)
0.1 0.9 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.1 0.5 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 0.2 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 0.2 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.1 1.7 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 1.0 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.3 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.1 0.4 GO:0007320 insemination(GO:0007320)
0.1 0.9 GO:0030497 fatty acid elongation(GO:0030497)
0.1 0.2 GO:0046110 xanthine metabolic process(GO:0046110)
0.1 0.9 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.5 GO:0097475 motor neuron migration(GO:0097475)
0.1 1.4 GO:0033194 response to hydroperoxide(GO:0033194)
0.1 0.9 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.4 GO:0006537 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.7 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.1 0.4 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.4 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 0.3 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.3 GO:0001658 branching involved in ureteric bud morphogenesis(GO:0001658) ureteric bud morphogenesis(GO:0060675) mesonephric tubule morphogenesis(GO:0072171)
0.0 0.3 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 9.7 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.2 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.8 GO:0048305 positive regulation of defense response to virus by host(GO:0002230) immunoglobulin secretion(GO:0048305)
0.0 1.5 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.6 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.4 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 1.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.0 1.4 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 0.5 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.2 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.7 GO:0007530 sex determination(GO:0007530)
0.0 0.7 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.2 GO:0006868 glutamine transport(GO:0006868)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.3 GO:0097264 self proteolysis(GO:0097264)
0.0 3.9 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.2 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.4 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.2 GO:1901162 serotonin biosynthetic process(GO:0042427) indole-containing compound biosynthetic process(GO:0042435) primary amino compound biosynthetic process(GO:1901162)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.8 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.3 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.2 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 3.5 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 0.7 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.6 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0 0.3 GO:0030953 astral microtubule organization(GO:0030953)
0.0 0.8 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.7 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.4 GO:0045056 transcytosis(GO:0045056)
0.0 0.4 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.3 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.4 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.2 GO:0032570 response to progesterone(GO:0032570)
0.0 0.7 GO:0034508 centromere complex assembly(GO:0034508)
0.0 0.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.7 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.3 GO:0042438 melanin biosynthetic process(GO:0042438)
0.0 0.3 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.1 GO:0048385 regulation of retinoic acid receptor signaling pathway(GO:0048385) positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.0 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0 0.2 GO:0010225 response to UV-C(GO:0010225)
0.0 0.4 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.4 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.0 0.8 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.2 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.0 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.7 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.2 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.0 GO:0060023 soft palate development(GO:0060023)
0.0 0.4 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 0.3 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 5.0 GO:0060187 cell pole(GO:0060187)
0.7 2.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.6 3.2 GO:0031523 Myb complex(GO:0031523)
0.3 1.6 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.3 1.5 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.2 1.5 GO:0005726 perichromatin fibrils(GO:0005726)
0.2 1.6 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 2.3 GO:0005614 interstitial matrix(GO:0005614)
0.1 10.7 GO:0070469 respiratory chain(GO:0070469)
0.1 0.5 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.1 0.5 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 1.9 GO:0051286 cell tip(GO:0051286)
0.1 0.1 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.1 2.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.7 GO:0001940 male pronucleus(GO:0001940)
0.1 0.2 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 4.9 GO:0016459 myosin complex(GO:0016459)
0.1 0.2 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 6.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 0.3 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.1 0.4 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.1 0.8 GO:0042581 specific granule(GO:0042581)
0.1 0.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 1.9 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 1.5 GO:0097440 apical dendrite(GO:0097440)
0.0 2.0 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.8 GO:0071565 nBAF complex(GO:0071565)
0.0 0.2 GO:0000235 astral microtubule(GO:0000235)
0.0 1.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 1.0 GO:0035861 site of double-strand break(GO:0035861)
0.0 2.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 3.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 2.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.3 GO:0042588 zymogen granule(GO:0042588)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.7 GO:0030673 axolemma(GO:0030673)
0.0 0.4 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.5 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 4.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.2 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.7 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.3 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.5 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 1.6 GO:0000776 kinetochore(GO:0000776)
0.0 1.3 GO:0032993 protein-DNA complex(GO:0032993)
0.0 1.7 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.9 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 2.2 GO:0030426 growth cone(GO:0030426)
0.0 0.6 GO:0005720 nuclear heterochromatin(GO:0005720)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 8.6 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
1.0 6.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.8 3.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.4 1.6 GO:0004126 cytidine deaminase activity(GO:0004126)
0.4 4.7 GO:0038191 neuropilin binding(GO:0038191)
0.3 4.1 GO:0050693 LBD domain binding(GO:0050693)
0.3 9.0 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.3 0.9 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.3 0.8 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.3 2.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.2 1.6 GO:0000150 recombinase activity(GO:0000150)
0.2 1.3 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.2 0.9 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.2 1.5 GO:0034056 estrogen response element binding(GO:0034056)
0.2 0.8 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.2 1.0 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.2 1.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.2 0.5 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 9.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 0.8 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.9 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 2.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 6.9 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 1.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 1.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 1.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.5 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.5 GO:0051378 primary amine oxidase activity(GO:0008131) serotonin binding(GO:0051378)
0.1 2.1 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 1.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 2.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.9 GO:0043422 protein kinase B binding(GO:0043422)
0.1 0.3 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 5.0 GO:0030507 spectrin binding(GO:0030507)
0.1 0.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.4 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 0.5 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 0.2 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 0.5 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.2 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.1 0.2 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 0.2 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.2 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.7 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.6 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.1 GO:0098809 nitrite reductase activity(GO:0098809)
0.0 1.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.3 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.3 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 1.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 2.0 GO:0005507 copper ion binding(GO:0005507)
0.0 0.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.4 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 1.1 GO:0070412 R-SMAD binding(GO:0070412)
0.0 2.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.5 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0033142 progesterone receptor binding(GO:0033142)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 0.4 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.8 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.3 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 5.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 1.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 1.9 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.7 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 1.1 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 1.4 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.3 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.1 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.2 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.3 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 2.2 GO:0004386 helicase activity(GO:0004386)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.4 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 5.5 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.9 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 3.0 GO:0008017 microtubule binding(GO:0008017)
0.0 0.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.2 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.2 6.1 PID_ARF6_PATHWAY Arf6 signaling events
0.2 9.5 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 7.0 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 4.0 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.1 1.9 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.1 2.4 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.1 3.8 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.1 1.8 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 3.7 PID_E2F_PATHWAY E2F transcription factor network
0.0 4.7 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.8 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 1.8 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 1.7 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 2.2 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.2 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 1.0 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.7 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 1.3 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.4 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 0.3 PID_BARD1_PATHWAY BARD1 signaling events
0.0 0.2 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.3 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.4 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.1 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 2.2 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.2 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.2 PID_ATR_PATHWAY ATR signaling pathway
0.0 0.5 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.6 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.3 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.2 PID_ATM_PATHWAY ATM pathway
0.0 1.5 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 PID_RHOA_REG_PATHWAY Regulation of RhoA activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.5 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.2 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.1 2.6 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.1 0.9 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 1.5 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 5.0 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.1 0.4 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 1.8 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 2.0 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 1.5 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 1.5 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 2.2 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.7 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.5 REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.5 REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.3 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 3.8 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 5.7 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.9 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 1.8 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.9 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.5 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 0.4 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.8 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.2 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.8 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.5 REACTOME_DOUBLE_STRAND_BREAK_REPAIR Genes involved in Double-Strand Break Repair
0.0 0.4 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 2.0 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.0 0.4 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.7 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.4 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.2 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.2 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)