Motif ID: Gzf1

Z-value: 0.293


Transcription factors associated with Gzf1:

Gene SymbolEntrez IDGene Name
Gzf1 ENSMUSG00000027439.9 Gzf1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gzf1mm10_v2_chr2_+_148681023_148681197-0.444.3e-03Click!


Activity profile for motif Gzf1.

activity profile for motif Gzf1


Sorted Z-values histogram for motif Gzf1

Sorted Z-values for motif Gzf1



Network of associatons between targets according to the STRING database.



First level regulatory network of Gzf1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_55915870 0.635 ENSMUST00000074828.4
Rpl21-ps6
ribosomal protein L21, pseudogene 6
chr14_+_11227511 0.561 ENSMUST00000080237.3
Rpl21-ps4
ribosomal protein L21, pseudogene 4
chr14_+_19751257 0.546 ENSMUST00000022340.3
Nid2
nidogen 2
chr4_-_134128707 0.525 ENSMUST00000105879.1
ENSMUST00000030651.8
Sh3bgrl3

SH3 domain binding glutamic acid-rich protein-like 3

chr8_+_105855086 0.499 ENSMUST00000040445.7
Thap11
THAP domain containing 11
chr9_-_116175318 0.493 ENSMUST00000061101.4
ENSMUST00000035014.6
Tgfbr2

transforming growth factor, beta receptor II

chr2_-_93996354 0.445 ENSMUST00000183110.1
Gm27027
predicted gene, 27027
chr4_+_129513581 0.359 ENSMUST00000062356.6
Marcksl1
MARCKS-like 1
chr17_+_47594629 0.359 ENSMUST00000182846.1
Ccnd3
cyclin D3
chr8_-_78508876 0.320 ENSMUST00000049245.7
Rbmxl1
RNA binding motif protein, X linked-like-1
chr4_+_154960915 0.272 ENSMUST00000049621.6
Hes5
hairy and enhancer of split 5 (Drosophila)
chr16_+_65815508 0.260 ENSMUST00000168064.1
Vgll3
vestigial like 3 (Drosophila)
chr4_-_129542710 0.255 ENSMUST00000102597.4
Hdac1
histone deacetylase 1
chr2_+_29827342 0.225 ENSMUST00000091142.3
Urm1
ubiquitin related modifier 1 homolog (S. cerevisiae)
chr7_-_29168647 0.214 ENSMUST00000048923.6
Spred3
sprouty-related, EVH1 domain containing 3
chr7_-_30612731 0.192 ENSMUST00000006476.4
Upk1a
uroplakin 1A
chr4_-_124862171 0.183 ENSMUST00000064444.7
Maneal
mannosidase, endo-alpha-like
chr8_+_78509319 0.180 ENSMUST00000034111.8
Slc10a7
solute carrier family 10 (sodium/bile acid cotransporter family), member 7
chr6_-_52012476 0.155 ENSMUST00000078214.5
Skap2
src family associated phosphoprotein 2
chr14_+_55854115 0.145 ENSMUST00000168479.1
Nynrin
NYN domain and retroviral integrase containing
chr9_-_57147034 0.135 ENSMUST00000034842.4
Neil1
nei endonuclease VIII-like 1 (E. coli)
chr2_-_153632775 0.106 ENSMUST00000071852.3
Commd7
COMM domain containing 7
chr14_+_55853997 0.089 ENSMUST00000100529.3
Nynrin
NYN domain and retroviral integrase containing
chr13_+_37826225 0.059 ENSMUST00000128570.1
Rreb1
ras responsive element binding protein 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0003274 endocardial cushion fusion(GO:0003274)
0.1 0.3 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.0 0.3 GO:0061198 fungiform papilla formation(GO:0061198) positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.2 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.4 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.1 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.2 GO:0000188 inactivation of MAPK activity(GO:0000188)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.3 GO:0016580 Sin3 complex(GO:0016580)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.3 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.0 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 0.5 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.3 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)