Motif ID: Hoxa3

Z-value: 0.414


Transcription factors associated with Hoxa3:

Gene SymbolEntrez IDGene Name
Hoxa3 ENSMUSG00000079560.7 Hoxa3



Activity profile for motif Hoxa3.

activity profile for motif Hoxa3


Sorted Z-values histogram for motif Hoxa3

Sorted Z-values for motif Hoxa3



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_55782500 3.250 ENSMUST00000075422.4
 Mab21l1
mab-21-like 1 (C. elegans)
chr6_+_8948608 2.923 ENSMUST00000160300.1
 Nxph1
neurexophilin 1
chr3_-_86548268 1.644 ENSMUST00000077524.3
 Mab21l2
mab-21-like 2 (C. elegans)
chr13_-_102906046 1.570 ENSMUST00000171791.1
 Mast4
microtubule associated serine/threonine kinase family member 4
chr13_-_102905740 1.130 ENSMUST00000167462.1
 Mast4
microtubule associated serine/threonine kinase family member 4
chr2_-_164171113 1.069 ENSMUST00000045196.3
 Kcns1
K+ voltage-gated channel, subfamily S, 1
chr4_-_14621805 0.921 ENSMUST00000042221.7
 Slc26a7
solute carrier family 26, member 7
chr3_+_159839729 0.920 ENSMUST00000068952.5
 Wls
wntless homolog (Drosophila)
chr4_-_14621669 0.917 ENSMUST00000143105.1
 Slc26a7
solute carrier family 26, member 7
chr10_+_73821857 0.877 ENSMUST00000177128.1
ENSMUST00000064562.7
ENSMUST00000129404.2
ENSMUST00000105426.3
ENSMUST00000131321.2
ENSMUST00000126920.2
ENSMUST00000147189.2
ENSMUST00000105424.3
ENSMUST00000092420.6
ENSMUST00000105429.3
ENSMUST00000131724.2
ENSMUST00000152655.2
ENSMUST00000151116.2
ENSMUST00000155701.2
ENSMUST00000152819.2
ENSMUST00000125517.2
ENSMUST00000124046.1
ENSMUST00000149977.2
ENSMUST00000146682.1
ENSMUST00000177107.1
 Pcdh15



















protocadherin 15



















chr4_-_14621494 0.750 ENSMUST00000149633.1
 Slc26a7
solute carrier family 26, member 7
chr2_+_109917639 0.693 ENSMUST00000046548.7
ENSMUST00000111037.2
 Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr9_+_119063429 0.673 ENSMUST00000141185.1
ENSMUST00000126251.1
ENSMUST00000136561.1
 Vill


villin-like


chr17_-_70853482 0.657 ENSMUST00000118283.1
 Tgif1
TGFB-induced factor homeobox 1
chr2_-_168767136 0.655 ENSMUST00000029061.5
ENSMUST00000103074.1
 Sall4

sal-like 4 (Drosophila)

chr16_-_42340595 0.599 ENSMUST00000102817.4
 Gap43
growth associated protein 43
chr7_-_45103747 0.585 ENSMUST00000003512.7
 Fcgrt
Fc receptor, IgG, alpha chain transporter
chr14_+_64589802 0.583 ENSMUST00000180610.1
 A930011O12Rik
RIKEN cDNA A930011O12 gene
chr10_-_37138863 0.424 ENSMUST00000092584.5
 Marcks
myristoylated alanine rich protein kinase C substrate
chr2_-_168767029 0.421 ENSMUST00000075044.3
 Sall4
sal-like 4 (Drosophila)
chr10_+_37139558 0.321 ENSMUST00000062667.3
 5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr2_+_36230426 0.259 ENSMUST00000062069.5
 Ptgs1
prostaglandin-endoperoxide synthase 1
chr10_+_26772477 0.188 ENSMUST00000039557.7
 Arhgap18
Rho GTPase activating protein 18
chr15_-_11037968 0.077 ENSMUST00000058007.5
 Rxfp3
relaxin family peptide receptor 3
chr12_+_59013379 0.073 ENSMUST00000021379.7
 Gemin2
gem (nuclear organelle) associated protein 2
chr16_-_92400067 0.067 ENSMUST00000023672.8
 Rcan1
regulator of calcineurin 1
chr5_-_138187177 0.052 ENSMUST00000110937.1
ENSMUST00000139276.1
ENSMUST00000048698.7
ENSMUST00000123415.1
 Taf6



TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor



chr10_+_23894688 0.050 ENSMUST00000041416.7
 Vnn1
vanin 1
chr6_+_63255971 0.049 ENSMUST00000159561.1
ENSMUST00000095852.3
 Grid2

glutamate receptor, ionotropic, delta 2

chr5_-_137531952 0.036 ENSMUST00000140139.1
 Gnb2
guanine nucleotide binding protein (G protein), beta 2
chrX_-_143933089 0.023 ENSMUST00000087313.3
 Dcx
doublecortin
chr8_-_109251698 0.020 ENSMUST00000079189.3
 4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr11_+_95384662 0.004 ENSMUST00000021243.7
ENSMUST00000146556.1
 Slc35b1

solute carrier family 35, member B1

chr2_+_23069210 0.001 ENSMUST00000155602.1
 Acbd5
acyl-Coenzyme A binding domain containing 5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.6 GO:0019532 oxalate transport(GO:0019532)
0.3 0.9 GO:0061357 Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356) positive regulation of Wnt protein secretion(GO:0061357)
0.2 0.7 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.1 0.9 GO:0050957 equilibrioception(GO:0050957)
0.1 0.6 GO:0016198 axon choice point recognition(GO:0016198)
0.1 0.3 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.1 1.6 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 1.1 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 1.1 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.7 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.4 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.7 GO:0051693 actin filament capping(GO:0051693)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.6 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.9 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 1.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.6 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.1 0.6 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.9 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 0.6 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 1.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.7 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.7 GO:0070410 co-SMAD binding(GO:0070410)
0.0 3.2 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 2.7 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID_NCADHERIN_PATHWAY N-cadherin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.1 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 2.6 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.7 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds