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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr15_-_8710734	5.339	ENSMUST00000005493.7	Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr15_-_8710409	4.746	ENSMUST00000157065.1	Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr14_+_80000292	2.912	ENSMUST00000088735.3	Olfm4	olfactomedin 4
chr6_-_137169710	1.931	ENSMUST00000117919.1	Rerg	RAS-like, estrogen-regulated, growth-inhibitor
chr4_-_14621805	1.580	ENSMUST00000042221.7	Slc26a7	solute carrier family 26, member 7
chr15_-_37458523	1.454	ENSMUST00000116445.2	Ncald	neurocalcin delta
chr18_+_37518341	1.143	ENSMUST00000097609.1	Pcdhb22	protocadherin beta 22
chr2_+_109917639	1.038	ENSMUST00000046548.7 ENSMUST00000111037.2	Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4
chr2_+_125136692	1.012	ENSMUST00000099452.2	Ctxn2	cortexin 2
chr10_+_97482350	0.950	ENSMUST00000163448.2	Dcn	decorin
chr8_+_45885479	0.945	ENSMUST00000034053.5	Pdlim3	PDZ and LIM domain 3
chr6_+_30541582	0.850	ENSMUST00000096066.4	Cpa2	carboxypeptidase A2, pancreatic
chr4_-_14621494	0.816	ENSMUST00000149633.1	Slc26a7	solute carrier family 26, member 7
chr5_+_66968559	0.802	ENSMUST00000127184.1	Limch1	LIM and calponin homology domains 1
chr9_-_103228420	0.790	ENSMUST00000126359.1	Trf	transferrin
chr5_+_66968416	0.778	ENSMUST00000038188.7	Limch1	LIM and calponin homology domains 1
chr2_-_164171113	0.777	ENSMUST00000045196.3	Kcns1	K+ voltage-gated channel, subfamily S, 1
chr13_+_43785107	0.744	ENSMUST00000015540.2	Cd83	CD83 antigen
chr5_-_62766153	0.690	ENSMUST00000076623.4	Arap2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr10_+_116018213	0.684	ENSMUST00000063470.4	Ptprr	protein tyrosine phosphatase, receptor type, R
chr4_-_14621669	0.656	ENSMUST00000143105.1	Slc26a7	solute carrier family 26, member 7
chr3_-_59220150	0.628	ENSMUST00000170388.1	P2ry12	purinergic receptor P2Y, G-protein coupled 12
chr17_-_45659312	0.582	ENSMUST00000120717.1	Capn11	calpain 11
chr9_-_55919605	0.576	ENSMUST00000037408.8	Scaper	S phase cyclin A-associated protein in the ER
chr2_-_45117349	0.572	ENSMUST00000176438.2	Zeb2	zinc finger E-box binding homeobox 2
chr13_+_42681513	0.566	ENSMUST00000149235.1	Phactr1	phosphatase and actin regulator 1
chr8_+_94152607	0.560	ENSMUST00000034211.8	Mt3	metallothionein 3
chr5_+_29195983	0.552	ENSMUST00000160888.1 ENSMUST00000159272.1 ENSMUST00000001247.5 ENSMUST00000161398.1 ENSMUST00000160246.1	Rnf32	ring finger protein 32
chr6_-_118479237	0.541	ENSMUST00000161170.1	Zfp9	zinc finger protein 9
chr2_+_36230426	0.534	ENSMUST00000062069.5	Ptgs1	prostaglandin-endoperoxide synthase 1
chrX_-_143933089	0.528	ENSMUST00000087313.3	Dcx	doublecortin
chr15_-_67113909	0.500	ENSMUST00000092640.5	St3gal1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr4_+_108719649	0.489	ENSMUST00000178992.1	3110021N24Rik	RIKEN cDNA 3110021N24 gene
chr18_+_23753708	0.487	ENSMUST00000115830.1	Mapre2	microtubule-associated protein, RP/EB family, member 2
chr19_-_32196393	0.472	ENSMUST00000151822.1	Sgms1	sphingomyelin synthase 1
chr2_+_32606979	0.457	ENSMUST00000113289.1 ENSMUST00000095044.3	St6galnac6	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr1_-_134955847	0.434	ENSMUST00000168381.1	Ppp1r12b	protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr2_+_32606946	0.430	ENSMUST00000113290.1	St6galnac6	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chrX_-_143933204	0.421	ENSMUST00000112851.1 ENSMUST00000112856.2 ENSMUST00000033642.3	Dcx	doublecortin
chr4_+_102589687	0.419	ENSMUST00000097949.4 ENSMUST00000106901.1	Pde4b	phosphodiesterase 4B, cAMP specific
chr1_-_134955908	0.415	ENSMUST00000045665.6 ENSMUST00000086444.4 ENSMUST00000112163.1	Ppp1r12b	protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr12_-_87775755	0.392	ENSMUST00000164517.2	Gm21319	predicted gene, 21319
chr3_-_66296807	0.391	ENSMUST00000029419.7	Veph1	ventricular zone expressed PH domain-containing 1
chr17_+_88440711	0.384	ENSMUST00000112238.2 ENSMUST00000155640.1	Foxn2	forkhead box N2
chr19_+_5474681	0.374	ENSMUST00000165485.1 ENSMUST00000166253.1 ENSMUST00000167371.1 ENSMUST00000167855.1 ENSMUST00000070118.7	Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2
chr19_-_50678642	0.363	ENSMUST00000072685.6 ENSMUST00000164039.2	Sorcs1	VPS10 domain receptor protein SORCS 1
chr13_-_81710937	0.359	ENSMUST00000161920.1 ENSMUST00000048993.5	Polr3g	polymerase (RNA) III (DNA directed) polypeptide G
chr2_-_177267036	0.346	ENSMUST00000108963.1	Gm14409	predicted gene 14409
chr3_+_55461758	0.340	ENSMUST00000070418.4	Dclk1	doublecortin-like kinase 1
chr6_+_145934113	0.323	ENSMUST00000032383.7	Sspn	sarcospan
chr6_+_63255971	0.307	ENSMUST00000159561.1 ENSMUST00000095852.3	Grid2	glutamate receptor, ionotropic, delta 2
chr11_-_82890541	0.304	ENSMUST00000092844.6 ENSMUST00000021033.9 ENSMUST00000018985.8	Rad51d	RAD51 homolog D
chr9_-_90255927	0.276	ENSMUST00000144646.1	Tbc1d2b	TBC1 domain family, member 2B
chr19_-_53944621	0.247	ENSMUST00000135402.2	Bbip1	BBSome interacting protein 1
chr7_-_46667375	0.237	ENSMUST00000107669.2	Tph1	tryptophan hydroxylase 1
chr14_-_36919314	0.237	ENSMUST00000182797.1	Ccser2	coiled-coil serine rich 2
chr9_+_113812547	0.220	ENSMUST00000166734.2 ENSMUST00000111838.2 ENSMUST00000163895.2	Clasp2	CLIP associating protein 2
chr1_-_72284248	0.217	ENSMUST00000097698.4 ENSMUST00000027381.6	Pecr	peroxisomal trans-2-enoyl-CoA reductase
chr1_+_72284367	0.214	ENSMUST00000027380.5 ENSMUST00000141783.1	Tmem169	transmembrane protein 169
chr18_+_32067729	0.214	ENSMUST00000025243.3	Iws1	IWS1 homolog (S. cerevisiae)
chr19_-_41933276	0.209	ENSMUST00000075280.4 ENSMUST00000112123.2	Exosc1	exosome component 1
chr3_+_121291725	0.201	ENSMUST00000039442.7	Alg14	asparagine-linked glycosylation 14
chr2_+_69897255	0.193	ENSMUST00000131553.1	Ubr3	ubiquitin protein ligase E3 component n-recognin 3
chr11_+_29373618	0.191	ENSMUST00000040182.6 ENSMUST00000109477.1	Ccdc88a	coiled coil domain containing 88A
chr8_+_23411490	0.179	ENSMUST00000033952.7	Sfrp1	secreted frizzled-related protein 1
chr7_-_38019505	0.176	ENSMUST00000085513.4	Uri1	URI1, prefoldin-like chaperone
chr19_+_55895508	0.176	ENSMUST00000111646.1	Tcf7l2	transcription factor 7 like 2, T cell specific, HMG box
chr13_+_83732438	0.170	ENSMUST00000182701.1	C130071C03Rik	RIKEN cDNA C130071C03 gene
chr14_+_64589802	0.169	ENSMUST00000180610.1	A930011O12Rik	RIKEN cDNA A930011O12 gene
chr7_+_35802593	0.162	ENSMUST00000052454.2	E130304I02Rik	RIKEN cDNA E130304I02 gene
chr2_-_116067391	0.142	ENSMUST00000140185.1	2700033N17Rik	RIKEN cDNA 2700033N17 gene
chr17_-_36032682	0.137	ENSMUST00000102678.4	H2-T23	histocompatibility 2, T region locus 23
chr7_+_103550368	0.126	ENSMUST00000106888.1	Olfr613	olfactory receptor 613
chr2_+_116067213	0.121	ENSMUST00000152412.1	G630016G05Rik	RIKEN cDNA G630016G05 gene
chr2_+_69897220	0.113	ENSMUST00000055758.9 ENSMUST00000112251.2	Ubr3	ubiquitin protein ligase E3 component n-recognin 3
chr5_-_62765618	0.111	ENSMUST00000159470.1	Arap2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr4_+_145585166	0.111	ENSMUST00000105739.1 ENSMUST00000119718.1	Gm13212	predicted gene 13212
chr10_-_20725023	0.107	ENSMUST00000020165.7	Pde7b	phosphodiesterase 7B
chr18_+_55057557	0.106	ENSMUST00000181765.1	Gm4221	predicted gene 4221
chrX_+_16619698	0.070	ENSMUST00000026013.5	Maoa	monoamine oxidase A
chr7_+_126950687	0.061	ENSMUST00000106333.1	Sez6l2	seizure related 6 homolog like 2
chr18_-_3281036	0.053	ENSMUST00000049942.6 ENSMUST00000139537.1 ENSMUST00000124747.1	Crem	cAMP responsive element modulator
chr7_-_83550258	0.051	ENSMUST00000177929.1	Gm10610	predicted gene 10610
chr2_+_110597298	0.045	ENSMUST00000045972.6 ENSMUST00000111026.2	Slc5a12	solute carrier family 5 (sodium/glucose cotransporter), member 12
chr1_-_132367879	0.040	ENSMUST00000142609.1	Tmcc2	transmembrane and coiled-coil domains 2
chr6_+_37870786	0.017	ENSMUST00000120428.1 ENSMUST00000031859.7	Trim24	tripartite motif-containing 24
chr15_+_98571004	0.006	ENSMUST00000023728.6	4930415O20Rik	RIKEN cDNA 4930415O20 gene

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.5	10.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.4	3.1	GO:0019532	oxalate transport(GO:0019532)
0.3	1.0	GO:0072204	cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.3	1.2	GO:0010700	negative regulation of norepinephrine secretion(GO:0010700)
0.2	0.6	GO:0097212	lysosomal membrane organization(GO:0097212)
0.2	0.7	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.1	1.0	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1	0.7	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
0.1	0.8	GO:0098707	positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.1	0.9	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	0.6	GO:1903056	positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1	0.2	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
0.1	0.3	GO:0071596	ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1	0.9	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.1	2.9	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1	0.2	GO:1904956	regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.1	0.5	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.1	0.3	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
0.0	0.1	GO:2000564	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.0	0.2	GO:1903566	positive regulation of protein localization to cilium(GO:1903566)
0.0	0.8	GO:1902259	regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0	0.4	GO:1901898	negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0	0.2	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0	0.2	GO:0000414	regulation of histone H3-K36 methylation(GO:0000414)
0.0	0.2	GO:1901162	serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0	0.2	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.3	GO:1904861	excitatory synapse assembly(GO:1904861)
0.0	0.2	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0	0.1	GO:0042420	dopamine catabolic process(GO:0042420)
0.0	1.5	GO:0003073	regulation of systemic arterial blood pressure(GO:0003073)
0.0	0.2	GO:0030497	fatty acid elongation(GO:0030497)
0.0	0.5	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.0	2.1	GO:0031032	actomyosin structure organization(GO:0031032)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.9	GO:0042581	specific granule(GO:0042581)
0.1	0.8	GO:0097433	dense body(GO:0097433)
0.1	0.6	GO:0008021	synaptic vesicle(GO:0008021) exocytic vesicle(GO:0070382)
0.1	0.3	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1	0.2	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.1	1.0	GO:0098644	complex of collagen trimers(GO:0098644)
0.0	0.5	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	10.8	GO:0043197	dendritic spine(GO:0043197)
0.0	1.1	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.2	GO:0034464	BBSome(GO:0034464)
0.0	0.8	GO:0031672	A band(GO:0031672)
0.0	0.2	GO:0070369	beta-catenin-TCF7L2 complex(GO:0070369)
0.0	0.3	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.2	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.4	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.5	GO:0035371	microtubule plus-end(GO:0035371)
0.0	0.5	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	0.9	GO:0030018	Z disc(GO:0030018)
0.0	0.6	GO:0045202	synapse(GO:0045202)
0.0	0.2	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.1	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.6	GO:0016235	aggresome(GO:0016235)
0.0	2.8	GO:0016323	basolateral plasma membrane(GO:0016323)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	10.1	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.3	3.1	GO:0019531	secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.1	0.9	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1	0.5	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.8	GO:0015091	ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1	0.5	GO:0033188	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1	0.6	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	1.0	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.1	0.2	GO:0004510	tryptophan 5-monooxygenase activity(GO:0004510)
0.1	0.2	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.8	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.3	GO:0000150	recombinase activity(GO:0000150)
0.0	0.8	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	1.5	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.6	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.9	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.2	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0004984	olfactory receptor activity(GO:0004984)
0.0	0.6	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.1	GO:0051378	primary amine oxidase activity(GO:0008131) serotonin binding(GO:0051378)
0.0	0.1	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
0.0	0.8	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.9	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.5	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.6	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.3	GO:0005234	extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0	0.5	GO:0004601	peroxidase activity(GO:0004601)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.0	NABA_PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.9	PID_LIS1_PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.8	PID_ARF6_PATHWAY	Arf6 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	8.8	REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.1	1.5	REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	0.6	REACTOME_P2Y_RECEPTORS	Genes involved in P2Y receptors
0.1	1.0	REACTOME_CS_DS_DEGRADATION	Genes involved in CS/DS degradation
0.1	3.1	REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	0.5	REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.6	REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	0.2	REACTOME_AMINE_DERIVED_HORMONES	Genes involved in Amine-derived hormones
0.0	0.2	REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.8	REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.5	REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.4	REACTOME_DARPP_32_EVENTS	Genes involved in DARPP-32 events

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