Motif ID: Hoxb7

Z-value: 4.171


Transcription factors associated with Hoxb7:

Gene SymbolEntrez IDGene Name
Hoxb7 ENSMUSG00000038721.8 Hoxb7



Activity profile for motif Hoxb7.

activity profile for motif Hoxb7


Sorted Z-values histogram for motif Hoxb7

Sorted Z-values for motif Hoxb7



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxb7

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_+_83504032 50.144 ENSMUST00000163888.1
ENSMUST00000005722.7
Mef2c

myocyte enhancer factor 2C

chr12_-_31713873 42.411 ENSMUST00000057783.4
ENSMUST00000174480.2
ENSMUST00000176710.1
Gpr22


G protein-coupled receptor 22


chrX_-_43167817 37.289 ENSMUST00000115058.1
ENSMUST00000115059.1
Tenm1

teneurin transmembrane protein 1

chr15_+_21111452 32.503 ENSMUST00000075132.6
Cdh12
cadherin 12
chr4_+_13751297 30.471 ENSMUST00000105566.2
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_-_136171722 28.255 ENSMUST00000053880.6
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr6_+_15196949 26.069 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
Foxp2



forkhead box P2



chr4_+_102589687 25.181 ENSMUST00000097949.4
ENSMUST00000106901.1
Pde4b

phosphodiesterase 4B, cAMP specific

chr9_-_112187766 23.740 ENSMUST00000111872.2
ENSMUST00000164754.2
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr17_-_90088343 21.487 ENSMUST00000173917.1
Nrxn1
neurexin I
chr19_+_26605106 21.024 ENSMUST00000025862.7
ENSMUST00000176030.1
Smarca2

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

chrM_+_10167 20.881 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr8_-_109251698 20.068 ENSMUST00000079189.3
4922502B01Rik
RIKEN cDNA 4922502B01 gene
chrM_+_7759 19.833 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr10_-_64090265 19.417 ENSMUST00000105439.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr6_-_144209558 18.759 ENSMUST00000111749.1
ENSMUST00000170367.2
Sox5

SRY-box containing gene 5

chr9_-_112187898 18.674 ENSMUST00000178410.1
ENSMUST00000172380.3
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr6_-_144209471 18.630 ENSMUST00000038815.7
Sox5
SRY-box containing gene 5
chr2_+_65930117 18.549 ENSMUST00000176109.1
Csrnp3
cysteine-serine-rich nuclear protein 3
chrM_+_7005 17.956 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr6_-_144209448 17.743 ENSMUST00000077160.5
Sox5
SRY-box containing gene 5
chrX_+_112615301 17.198 ENSMUST00000122805.1
Zfp711
zinc finger protein 711
chr4_-_14621805 17.125 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr14_-_93888732 17.070 ENSMUST00000068992.2
Pcdh9
protocadherin 9
chr6_-_13839916 17.059 ENSMUST00000060442.7
Gpr85
G protein-coupled receptor 85
chr3_-_26133734 16.590 ENSMUST00000108308.3
ENSMUST00000075054.4
Nlgn1

neuroligin 1

chrX_-_43274786 16.227 ENSMUST00000016294.7
Tenm1
teneurin transmembrane protein 1
chrX_+_112604274 16.079 ENSMUST00000071814.6
Zfp711
zinc finger protein 711
chr2_-_45112890 16.008 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chr15_+_92597104 15.981 ENSMUST00000035399.8
Pdzrn4
PDZ domain containing RING finger 4
chr11_-_30198232 15.963 ENSMUST00000102838.3
Sptbn1
spectrin beta, non-erythrocytic 1
chr15_-_48791933 15.933 ENSMUST00000160658.1
ENSMUST00000100670.3
ENSMUST00000162830.1
Csmd3


CUB and Sushi multiple domains 3


chr2_-_7395968 15.880 ENSMUST00000002176.6
Celf2
CUGBP, Elav-like family member 2
chr2_-_7395879 15.841 ENSMUST00000182404.1
Celf2
CUGBP, Elav-like family member 2
chr2_+_65620829 15.236 ENSMUST00000028377.7
Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr6_+_96113146 15.129 ENSMUST00000122120.1
Fam19a1
family with sequence similarity 19, member A1
chr13_+_16014457 14.879 ENSMUST00000164993.1
Inhba
inhibin beta-A
chr10_+_90576252 14.753 ENSMUST00000182427.1
ENSMUST00000182053.1
ENSMUST00000182113.1
Anks1b


ankyrin repeat and sterile alpha motif domain containing 1B


chr2_-_7396192 14.581 ENSMUST00000137733.2
Celf2
CUGBP, Elav-like family member 2
chr11_+_31872100 14.503 ENSMUST00000020543.6
ENSMUST00000109412.2
Cpeb4

cytoplasmic polyadenylation element binding protein 4

chr1_+_66321708 14.439 ENSMUST00000114013.1
Map2
microtubule-associated protein 2
chr6_+_15185456 14.412 ENSMUST00000115472.1
ENSMUST00000115474.1
ENSMUST00000031545.7
ENSMUST00000137628.1
Foxp2



forkhead box P2



chr16_+_7069825 14.272 ENSMUST00000056416.7
Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr3_-_141982224 14.195 ENSMUST00000029948.8
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr10_-_64090241 13.883 ENSMUST00000133588.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr19_+_26749726 13.872 ENSMUST00000175842.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_-_126830632 13.808 ENSMUST00000112583.1
ENSMUST00000094609.3
Nckap5

NCK-associated protein 5

chr1_-_24612700 13.753 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chr1_+_159737510 13.199 ENSMUST00000111669.3
Tnr
tenascin R
chr10_-_109009055 13.159 ENSMUST00000156979.1
Syt1
synaptotagmin I
chr2_+_37516618 12.994 ENSMUST00000065441.6
Gpr21
G protein-coupled receptor 21
chr10_-_45470201 12.950 ENSMUST00000079390.6
Lin28b
lin-28 homolog B (C. elegans)
chr19_+_26750939 12.890 ENSMUST00000175953.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chrM_+_9870 12.498 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr19_-_14597983 12.391 ENSMUST00000052011.7
Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr10_-_109010955 12.351 ENSMUST00000105276.1
ENSMUST00000064054.7
Syt1

synaptotagmin I

chr2_+_96318014 12.329 ENSMUST00000135431.1
ENSMUST00000162807.2
Lrrc4c

leucine rich repeat containing 4C

chr11_+_29463735 12.169 ENSMUST00000155854.1
Ccdc88a
coiled coil domain containing 88A
chr19_-_14598031 12.164 ENSMUST00000167776.2
Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr9_-_29963112 12.046 ENSMUST00000075069.4
Ntm
neurotrimin
chr2_+_68104671 11.944 ENSMUST00000042456.3
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr1_+_34005872 11.879 ENSMUST00000182296.1
Dst
dystonin
chr1_-_56969864 11.822 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr2_-_7081256 11.703 ENSMUST00000183209.1
Celf2
CUGBP, Elav-like family member 2
chr2_-_7081207 11.547 ENSMUST00000114923.2
ENSMUST00000182706.1
Celf2

CUGBP, Elav-like family member 2

chr15_+_92161343 11.486 ENSMUST00000068378.5
Cntn1
contactin 1
chr11_-_42000834 11.437 ENSMUST00000070725.4
Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr15_-_66812593 11.303 ENSMUST00000100572.3
Sla
src-like adaptor
chr13_-_89742244 11.258 ENSMUST00000109543.2
ENSMUST00000159337.1
ENSMUST00000159910.1
ENSMUST00000109544.2
Vcan



versican



chr9_-_101198999 11.216 ENSMUST00000066773.7
Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr11_-_76509419 11.208 ENSMUST00000094012.4
Abr
active BCR-related gene
chr1_-_25228814 11.157 ENSMUST00000126626.1
Bai3
brain-specific angiogenesis inhibitor 3
chr1_-_56969827 11.145 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr2_-_6884940 10.965 ENSMUST00000183091.1
ENSMUST00000182851.1
Celf2

CUGBP, Elav-like family member 2

chr2_+_71528657 10.938 ENSMUST00000126400.1
Dlx1
distal-less homeobox 1
chr1_+_179961110 10.802 ENSMUST00000076687.5
ENSMUST00000097450.3
Cdc42bpa

CDC42 binding protein kinase alpha

chr14_-_36935560 10.744 ENSMUST00000183038.1
Ccser2
coiled-coil serine rich 2
chr14_-_124677089 10.741 ENSMUST00000095529.3
Fgf14
fibroblast growth factor 14
chr10_+_90576872 10.690 ENSMUST00000182550.1
ENSMUST00000099364.5
Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr3_+_67892189 10.656 ENSMUST00000063263.3
Iqcj
IQ motif containing J
chr4_-_14621494 10.610 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr17_-_81649607 10.604 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
Slc8a1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr8_+_54954728 10.490 ENSMUST00000033915.7
Gpm6a
glycoprotein m6a
chr1_-_126830786 10.480 ENSMUST00000162646.1
Nckap5
NCK-associated protein 5
chr12_+_29528382 10.302 ENSMUST00000049784.9
Myt1l
myelin transcription factor 1-like
chr3_+_55461758 10.290 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr13_+_93308006 10.274 ENSMUST00000079086.6
Homer1
homer homolog 1 (Drosophila)
chrM_+_2743 10.252 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr10_+_90576570 10.201 ENSMUST00000182786.1
ENSMUST00000182600.1
Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr2_-_65567505 10.167 ENSMUST00000100069.2
Scn3a
sodium channel, voltage-gated, type III, alpha
chr2_-_45113255 10.076 ENSMUST00000068415.4
ENSMUST00000127520.1
Zeb2

zinc finger E-box binding homeobox 2

chr8_-_67974567 10.070 ENSMUST00000098696.3
ENSMUST00000038959.9
ENSMUST00000093469.4
Psd3


pleckstrin and Sec7 domain containing 3


chrX_-_165327376 10.041 ENSMUST00000058787.8
Glra2
glycine receptor, alpha 2 subunit
chr13_+_83573577 9.864 ENSMUST00000185052.1
Mef2c
myocyte enhancer factor 2C
chr13_-_99516537 9.824 ENSMUST00000064762.4
Map1b
microtubule-associated protein 1B
chr18_-_31447383 9.742 ENSMUST00000025110.3
Syt4
synaptotagmin IV
chr7_+_91090697 9.706 ENSMUST00000107196.2
Dlg2
discs, large homolog 2 (Drosophila)
chr7_+_91090728 9.635 ENSMUST00000074273.3
Dlg2
discs, large homolog 2 (Drosophila)
chr5_+_107497762 9.599 ENSMUST00000152474.1
ENSMUST00000060553.7
A830010M20Rik

RIKEN cDNA A830010M20 gene

chr19_-_19001099 9.578 ENSMUST00000040153.8
ENSMUST00000112828.1
Rorb

RAR-related orphan receptor beta

chr4_-_35845204 9.511 ENSMUST00000164772.1
ENSMUST00000065173.2
Lingo2

leucine rich repeat and Ig domain containing 2

chr2_-_57113053 9.468 ENSMUST00000112627.1
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr13_-_101692624 9.457 ENSMUST00000035532.6
Pik3r1
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
chr9_+_32116040 9.424 ENSMUST00000174641.1
Arhgap32
Rho GTPase activating protein 32
chr4_+_102421518 9.220 ENSMUST00000106904.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr19_-_57239310 9.149 ENSMUST00000111559.1
Ablim1
actin-binding LIM protein 1
chr2_-_64975762 9.149 ENSMUST00000156765.1
Grb14
growth factor receptor bound protein 14
chr1_-_30863256 9.077 ENSMUST00000088310.3
Phf3
PHD finger protein 3
chr1_+_81077274 9.070 ENSMUST00000068275.5
ENSMUST00000113494.2
Nyap2

neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2

chr2_-_45117349 9.054 ENSMUST00000176438.2
Zeb2
zinc finger E-box binding homeobox 2
chr17_+_70561739 9.050 ENSMUST00000097288.2
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr11_-_42000284 9.028 ENSMUST00000109292.2
ENSMUST00000109290.1
Gabrg2

gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2

chrM_+_3906 8.990 ENSMUST00000082396.1
mt-Nd2
mitochondrially encoded NADH dehydrogenase 2
chr11_-_42000532 8.964 ENSMUST00000070735.3
Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr15_-_13173607 8.927 ENSMUST00000036439.4
Cdh6
cadherin 6
chr15_-_93595877 8.881 ENSMUST00000048982.4
Prickle1
prickle homolog 1 (Drosophila)
chr16_-_64786321 8.839 ENSMUST00000052588.4
Zfp654
zinc finger protein 654
chr9_-_112232449 8.824 ENSMUST00000035085.5
Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr16_+_19028232 8.797 ENSMUST00000074116.4
Gm10088
predicted gene 10088
chr10_+_90576777 8.784 ENSMUST00000183136.1
ENSMUST00000182595.1
Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr10_+_99263224 8.746 ENSMUST00000020118.4
Dusp6
dual specificity phosphatase 6
chr14_-_36919314 8.723 ENSMUST00000182797.1
Ccser2
coiled-coil serine rich 2
chr4_+_101507947 8.700 ENSMUST00000149047.1
ENSMUST00000106929.3
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr11_-_37235882 8.680 ENSMUST00000102801.1
Tenm2
teneurin transmembrane protein 2
chr2_-_6884975 8.678 ENSMUST00000114924.3
ENSMUST00000170438.1
ENSMUST00000114934.4
Celf2


CUGBP, Elav-like family member 2


chr2_-_63184253 8.639 ENSMUST00000075052.3
ENSMUST00000112454.1
Kcnh7

potassium voltage-gated channel, subfamily H (eag-related), member 7

chr19_+_26748268 8.623 ENSMUST00000175791.1
ENSMUST00000176698.1
ENSMUST00000177252.1
ENSMUST00000176475.1
ENSMUST00000112637.2
Smarca2




SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2




chr14_-_12345847 8.592 ENSMUST00000022262.4
Fezf2
Fez family zinc finger 2
chr6_+_137410721 8.590 ENSMUST00000167002.1
Ptpro
protein tyrosine phosphatase, receptor type, O
chr5_+_107497718 8.549 ENSMUST00000112671.2
A830010M20Rik
RIKEN cDNA A830010M20 gene
chr13_+_42680565 8.505 ENSMUST00000128646.1
Phactr1
phosphatase and actin regulator 1
chr9_-_16378231 8.492 ENSMUST00000082170.5
Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chrM_+_14138 8.462 ENSMUST00000082421.1
mt-Cytb
mitochondrially encoded cytochrome b
chrX_-_162565514 8.440 ENSMUST00000154424.1
Reps2
RALBP1 associated Eps domain containing protein 2
chr3_+_125404072 8.417 ENSMUST00000173932.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr13_-_41079628 8.417 ENSMUST00000165087.1
ENSMUST00000070193.6
Mak

male germ cell-associated kinase

chr13_+_76579670 8.400 ENSMUST00000126960.1
ENSMUST00000109583.2
Mctp1

multiple C2 domains, transmembrane 1

chr10_+_90576708 8.391 ENSMUST00000182430.1
ENSMUST00000182960.1
ENSMUST00000182045.1
ENSMUST00000182083.1
Anks1b



ankyrin repeat and sterile alpha motif domain containing 1B



chr12_+_69963452 8.384 ENSMUST00000110560.1
Gm3086
predicted gene 3086
chr3_+_26331150 8.358 ENSMUST00000099182.2
A830092H15Rik
RIKEN cDNA A830092H15 gene
chr5_-_23616528 8.347 ENSMUST00000088392.4
Srpk2
serine/arginine-rich protein specific kinase 2
chr1_+_66322102 8.312 ENSMUST00000123647.1
Map2
microtubule-associated protein 2
chr2_-_65567465 8.310 ENSMUST00000066432.5
Scn3a
sodium channel, voltage-gated, type III, alpha
chr2_-_80128834 8.265 ENSMUST00000102654.4
ENSMUST00000102655.3
Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr8_-_58911627 8.246 ENSMUST00000077447.4
Galntl6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
chr5_+_81021202 8.245 ENSMUST00000117253.1
ENSMUST00000120128.1
Lphn3

latrophilin 3

chr6_-_99044414 8.238 ENSMUST00000177507.1
ENSMUST00000123992.1
Foxp1

forkhead box P1

chr1_-_52190901 8.173 ENSMUST00000156887.1
ENSMUST00000129107.1
Gls

glutaminase

chr2_-_6722187 8.133 ENSMUST00000182657.1
Celf2
CUGBP, Elav-like family member 2
chr13_+_42681513 8.132 ENSMUST00000149235.1
Phactr1
phosphatase and actin regulator 1
chrX_-_143933204 8.070 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr5_+_81021583 8.041 ENSMUST00000121707.1
Lphn3
latrophilin 3
chr9_-_49798729 8.034 ENSMUST00000166811.2
Ncam1
neural cell adhesion molecule 1
chr17_+_70522083 8.030 ENSMUST00000148486.1
ENSMUST00000133717.1
Dlgap1

discs, large (Drosophila) homolog-associated protein 1

chr6_-_138421379 7.979 ENSMUST00000163065.1
Lmo3
LIM domain only 3
chr2_-_6721890 7.966 ENSMUST00000114927.2
Celf2
CUGBP, Elav-like family member 2
chr13_-_89742490 7.949 ENSMUST00000109546.2
Vcan
versican
chr9_-_49798905 7.943 ENSMUST00000114476.2
Ncam1
neural cell adhesion molecule 1
chr5_-_84417359 7.935 ENSMUST00000113401.1
Epha5
Eph receptor A5
chr4_-_76344227 7.924 ENSMUST00000050757.9
Ptprd
protein tyrosine phosphatase, receptor type, D
chr6_-_13838432 7.902 ENSMUST00000115492.1
Gpr85
G protein-coupled receptor 85
chr18_-_35215008 7.886 ENSMUST00000091636.3
Lrrtm2
leucine rich repeat transmembrane neuronal 2
chr4_+_13743424 7.884 ENSMUST00000006761.3
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr13_+_16011851 7.826 ENSMUST00000042603.6
Inhba
inhibin beta-A
chr1_+_66386968 7.814 ENSMUST00000145419.1
Map2
microtubule-associated protein 2
chr8_-_54718664 7.776 ENSMUST00000144711.2
ENSMUST00000093510.2
Wdr17

WD repeat domain 17

chr1_+_81077204 7.771 ENSMUST00000123720.1
Nyap2
neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2
chr9_+_47530173 7.645 ENSMUST00000114548.1
ENSMUST00000152459.1
ENSMUST00000143026.1
ENSMUST00000085909.2
ENSMUST00000114547.1
ENSMUST00000034581.3
Cadm1





cell adhesion molecule 1





chr10_-_6980376 7.633 ENSMUST00000105617.1
Ipcef1
interaction protein for cytohesin exchange factors 1
chr15_-_37459327 7.609 ENSMUST00000119730.1
ENSMUST00000120746.1
Ncald

neurocalcin delta

chr15_-_37458523 7.603 ENSMUST00000116445.2
Ncald
neurocalcin delta
chr1_+_153665666 7.594 ENSMUST00000111814.1
ENSMUST00000111810.1
Rgs8

regulator of G-protein signaling 8

chr2_+_61804453 7.587 ENSMUST00000048934.8
Tbr1
T-box brain gene 1
chr8_-_54724474 7.587 ENSMUST00000175915.1
Wdr17
WD repeat domain 17
chr3_-_126998408 7.537 ENSMUST00000182764.1
ENSMUST00000044443.8
Ank2

ankyrin 2, brain

chrX_-_143933089 7.529 ENSMUST00000087313.3
Dcx
doublecortin
chr13_-_105054895 7.443 ENSMUST00000063551.5
Rgs7bp
regulator of G-protein signalling 7 binding protein
chr2_-_45110241 7.438 ENSMUST00000177302.1
Zeb2
zinc finger E-box binding homeobox 2
chr18_+_36952621 7.434 ENSMUST00000115661.2
Pcdha2
protocadherin alpha 2
chr2_-_80129458 7.421 ENSMUST00000102653.1
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chrM_+_11734 7.349 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chr5_+_66968416 7.349 ENSMUST00000038188.7
Limch1
LIM and calponin homology domains 1
chr3_+_28263205 7.274 ENSMUST00000159236.2
Tnik
TRAF2 and NCK interacting kinase
chr3_+_84952146 7.259 ENSMUST00000029727.7
Fbxw7
F-box and WD-40 domain protein 7
chr4_+_101507855 7.198 ENSMUST00000038207.5
Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr9_-_55919605 7.198 ENSMUST00000037408.8
Scaper
S phase cyclin A-associated protein in the ER
chr1_+_153665274 7.178 ENSMUST00000152114.1
ENSMUST00000111812.1
Rgs8

regulator of G-protein signaling 8

chr3_-_17786834 7.122 ENSMUST00000099198.2
Gm10742
predicted gene 10742
chr1_-_37496095 7.038 ENSMUST00000148047.1
ENSMUST00000143636.1
Mgat4a

mannoside acetylglucosaminyltransferase 4, isoenzyme A

chr13_+_109926832 7.011 ENSMUST00000117420.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr15_-_42676967 6.998 ENSMUST00000022921.5
Angpt1
angiopoietin 1
chrX_+_41401128 6.984 ENSMUST00000115103.2
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr4_+_102254739 6.984 ENSMUST00000106907.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr6_-_55681257 6.980 ENSMUST00000044767.8
Neurod6
neurogenic differentiation 6
chr2_-_45110336 6.977 ENSMUST00000028229.6
ENSMUST00000152232.1
Zeb2

zinc finger E-box binding homeobox 2

chr15_+_4375462 6.945 ENSMUST00000061925.4
Plcxd3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr6_-_126166726 6.916 ENSMUST00000112244.2
ENSMUST00000050484.7
Ntf3

neurotrophin 3

chr17_+_3397189 6.890 ENSMUST00000072156.6
Tiam2
T cell lymphoma invasion and metastasis 2
chr6_-_138422898 6.885 ENSMUST00000161450.1
ENSMUST00000163024.1
ENSMUST00000162185.1
Lmo3


LIM domain only 3


chr4_+_28813125 6.850 ENSMUST00000029964.5
ENSMUST00000080934.4
Epha7

Eph receptor A7


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
20.0 60.0 GO:0007521 muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111)
9.3 56.1 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
8.6 34.3 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
6.3 56.4 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
6.2 49.8 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
6.2 24.8 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
5.9 17.6 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923)
5.3 16.0 GO:0001928 regulation of exocyst assembly(GO:0001928)
5.1 15.4 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
5.1 60.8 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
4.8 33.6 GO:0019532 oxalate transport(GO:0019532)
4.8 61.8 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
4.5 22.7 GO:0042636 negative regulation of hair cycle(GO:0042636) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
4.5 22.6 GO:0046684 response to pyrethroid(GO:0046684)
4.4 39.8 GO:0071420 cellular response to histamine(GO:0071420)
4.1 12.4 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
4.1 12.2 GO:0007525 somatic muscle development(GO:0007525)
4.1 36.6 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
3.8 15.1 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
3.5 14.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
3.5 10.6 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
3.5 24.2 GO:0005513 detection of calcium ion(GO:0005513)
3.3 10.0 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
3.2 9.5 GO:0017085 response to insecticide(GO:0017085)
3.1 12.6 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
3.1 18.5 GO:0072318 clathrin coat disassembly(GO:0072318)
3.0 9.1 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
3.0 12.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
3.0 33.1 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
3.0 35.8 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
2.9 8.8 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
2.8 8.3 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
2.8 112.8 GO:0006376 mRNA splice site selection(GO:0006376)
2.7 18.9 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
2.7 13.4 GO:0007256 activation of JNKK activity(GO:0007256)
2.6 7.9 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
2.6 10.5 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
2.5 7.6 GO:0009826 unidimensional cell growth(GO:0009826) susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
2.5 10.1 GO:0021764 amygdala development(GO:0021764)
2.5 19.6 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
2.4 12.2 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
2.3 11.5 GO:0006543 glutamine catabolic process(GO:0006543)
2.3 2.3 GO:0007113 endomitotic cell cycle(GO:0007113)
2.2 4.5 GO:2000790 regulation of mesenchymal cell proliferation involved in lung development(GO:2000790) negative regulation of mesenchymal cell proliferation involved in lung development(GO:2000791)
2.2 33.7 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
2.2 11.2 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
2.2 31.4 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
2.2 8.9 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
2.2 6.6 GO:0043379 memory T cell differentiation(GO:0043379)
2.2 6.6 GO:0006597 spermine biosynthetic process(GO:0006597)
2.2 11.0 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
2.2 17.4 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
2.1 8.6 GO:0003105 negative regulation of glomerular filtration(GO:0003105)
2.1 21.4 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
2.1 10.6 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
2.1 26.7 GO:0070842 aggresome assembly(GO:0070842)
2.0 8.2 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
2.0 8.1 GO:2000481 positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
2.0 2.0 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
1.9 9.7 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
1.9 5.6 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
1.9 9.4 GO:0035063 nuclear speck organization(GO:0035063)
1.9 16.8 GO:0010587 miRNA catabolic process(GO:0010587)
1.8 24.9 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
1.8 5.3 GO:0001543 ovarian follicle rupture(GO:0001543)
1.7 7.0 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
1.7 10.5 GO:0071294 cellular response to zinc ion(GO:0071294)
1.7 13.9 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
1.7 82.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
1.7 1.7 GO:0097324 melanocyte migration(GO:0097324)
1.7 8.5 GO:0033762 response to glucagon(GO:0033762)
1.7 5.0 GO:0050915 sensory perception of sour taste(GO:0050915)
1.7 1.7 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
1.7 9.9 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
1.6 4.9 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
1.6 27.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
1.5 9.0 GO:0086018 SA node cell action potential(GO:0086015) SA node cell to atrial cardiac muscle cell signalling(GO:0086018) SA node cell to atrial cardiac muscle cell communication(GO:0086070)
1.5 10.3 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
1.4 4.3 GO:1904978 regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
1.4 4.3 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
1.4 20.0 GO:0045161 neuronal ion channel clustering(GO:0045161)
1.4 4.2 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
1.4 9.6 GO:0046549 retinal cone cell development(GO:0046549)
1.4 5.4 GO:0038128 ERBB2 signaling pathway(GO:0038128)
1.4 4.1 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
1.3 55.2 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
1.3 6.6 GO:0048245 eosinophil chemotaxis(GO:0048245)
1.3 4.0 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
1.3 7.8 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
1.3 16.9 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
1.3 29.5 GO:0008090 retrograde axonal transport(GO:0008090)
1.3 22.5 GO:0046069 cGMP catabolic process(GO:0046069)
1.2 3.7 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
1.2 7.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
1.2 4.8 GO:1901475 pyruvate transmembrane transport(GO:1901475)
1.2 8.4 GO:1904017 response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
1.2 3.6 GO:0051582 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
1.2 10.4 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
1.1 17.2 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
1.1 9.1 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
1.1 3.4 GO:0007262 STAT protein import into nucleus(GO:0007262)
1.1 2.2 GO:0003289 septum primum development(GO:0003284) atrial septum primum morphogenesis(GO:0003289)
1.1 1.1 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
1.1 6.5 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
1.1 3.2 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
1.0 3.1 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
1.0 4.1 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
1.0 7.2 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
1.0 50.1 GO:0034605 cellular response to heat(GO:0034605)
1.0 5.9 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
1.0 1.0 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
1.0 2.9 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
1.0 3.9 GO:0021502 neural fold elevation formation(GO:0021502)
1.0 23.1 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
1.0 58.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
1.0 3.8 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.9 9.5 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.9 9.5 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.9 6.6 GO:0030035 microspike assembly(GO:0030035)
0.9 2.8 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.9 5.5 GO:1902287 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.9 4.6 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.9 1.8 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.9 3.6 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.9 3.6 GO:2000821 regulation of grooming behavior(GO:2000821)
0.9 4.4 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.9 14.1 GO:0051447 negative regulation of meiotic cell cycle(GO:0051447)
0.9 21.0 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.9 33.5 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.9 3.4 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.8 5.0 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.8 4.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.8 1.7 GO:0070343 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.8 3.3 GO:0044330 pyruvate transport(GO:0006848) canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330) lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.8 4.9 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.8 3.3 GO:0060178 regulation of exocyst localization(GO:0060178)
0.8 7.3 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.8 4.8 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.8 2.4 GO:0035864 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.8 5.6 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.8 10.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.8 8.6 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.8 6.8 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.7 3.7 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.7 4.3 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.7 19.6 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.7 18.1 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.7 2.1 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.7 2.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.7 3.4 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.7 8.0 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.7 1.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.7 2.6 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.6 5.8 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.6 1.9 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.6 1.3 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.6 10.2 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.6 4.4 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.6 10.5 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.6 0.6 GO:0060527 prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.6 4.8 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.6 1.7 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.6 2.9 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.6 3.4 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.6 5.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.6 4.5 GO:0018344 protein geranylgeranylation(GO:0018344)
0.6 23.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.6 4.0 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.6 7.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.6 2.8 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.6 1.7 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.6 2.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.6 15.5 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.6 5.0 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.5 2.1 GO:2000194 regulation of female gonad development(GO:2000194)
0.5 2.7 GO:0006041 glucosamine metabolic process(GO:0006041)
0.5 1.6 GO:1904395 positive regulation of postsynaptic membrane organization(GO:1901628) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) positive regulation of neuromuscular junction development(GO:1904398)
0.5 3.2 GO:0034773 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.5 2.1 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.5 1.6 GO:0061743 motor learning(GO:0061743)
0.5 2.0 GO:0048631 skeletal muscle tissue growth(GO:0048630) regulation of skeletal muscle tissue growth(GO:0048631)
0.5 3.0 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.5 5.9 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.5 3.4 GO:0030242 pexophagy(GO:0030242)
0.5 9.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.5 7.1 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.5 2.9 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.5 3.8 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.5 3.3 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.5 3.3 GO:2000232 regulation of rRNA processing(GO:2000232)
0.5 1.4 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.5 3.7 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.5 1.8 GO:0019323 pentose catabolic process(GO:0019323)
0.5 23.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.4 0.9 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.4 9.8 GO:0008340 determination of adult lifespan(GO:0008340)
0.4 3.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.4 5.3 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.4 3.5 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.4 16.8 GO:0001919 regulation of receptor recycling(GO:0001919)
0.4 0.4 GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
0.4 1.3 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.4 18.8 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.4 1.2 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.4 3.7 GO:0061635 regulation of protein complex stability(GO:0061635)
0.4 2.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.4 1.2 GO:0002329 pre-B cell differentiation(GO:0002329)
0.4 0.8 GO:0032763 regulation of mast cell cytokine production(GO:0032763) positive regulation of mast cell cytokine production(GO:0032765)
0.4 0.8 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.4 1.2 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.4 0.8 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.4 2.4 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.4 3.1 GO:0010818 T cell chemotaxis(GO:0010818)
0.4 8.0 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.4 1.9 GO:0007258 JUN phosphorylation(GO:0007258)
0.4 2.2 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.4 4.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.4 0.7 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.4 3.2 GO:0042118 endothelial cell activation(GO:0042118)
0.4 2.8 GO:0007625 grooming behavior(GO:0007625)
0.4 4.6 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.3 9.4 GO:0030325 adrenal gland development(GO:0030325)
0.3 1.4 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.3 1.0 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.3 1.7 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.3 16.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.3 1.7 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.3 2.0 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.3 7.1 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.3 1.7 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.3 4.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.3 3.0 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.3 3.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.3 4.3 GO:0010259 multicellular organism aging(GO:0010259)
0.3 1.3 GO:0070670 response to interleukin-4(GO:0070670)
0.3 0.9 GO:0071415 cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
0.3 1.3 GO:0097167 circadian regulation of translation(GO:0097167)
0.3 2.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.3 3.7 GO:0001553 luteinization(GO:0001553)
0.3 4.0 GO:0021860 pyramidal neuron development(GO:0021860)
0.3 8.8 GO:0007416 synapse assembly(GO:0007416)
0.3 1.2 GO:0050931 pigment cell differentiation(GO:0050931)
0.3 1.5 GO:0016198 axon choice point recognition(GO:0016198)
0.3 1.5 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.3 1.5 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.3 1.2 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.3 1.4 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.3 3.2 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.3 2.8 GO:1900364 regulation of mRNA polyadenylation(GO:1900363) negative regulation of mRNA polyadenylation(GO:1900364)
0.3 1.7 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.3 2.5 GO:0006449 regulation of translational termination(GO:0006449)
0.3 9.9 GO:0040018 positive regulation of multicellular organism growth(GO:0040018)
0.3 0.8 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.3 0.3 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.3 0.5 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.3 0.5 GO:0071649 negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865) regulation of chemokine (C-C motif) ligand 5 production(GO:0071649)
0.3 0.8 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.3 2.9 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.3 1.3 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.3 1.6 GO:0035095 behavioral response to nicotine(GO:0035095)
0.3 1.6 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.3 2.6 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.3 3.1 GO:0000729 DNA double-strand break processing(GO:0000729)
0.3 4.3 GO:0060074 synapse maturation(GO:0060074)
0.3 2.3 GO:0006020 inositol metabolic process(GO:0006020)
0.3 2.5 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.2 1.7 GO:0035094 response to nicotine(GO:0035094)
0.2 17.1 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.2 1.9 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.2 0.5 GO:0042637 catagen(GO:0042637) regulation of catagen(GO:0051794) positive regulation of catagen(GO:0051795)
0.2 1.4 GO:0031424 keratinization(GO:0031424)
0.2 3.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.2 3.8 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.2 3.1 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.2 1.6 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.2 2.1 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.2 0.7 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.2 1.2 GO:0060467 negative regulation of fertilization(GO:0060467)
0.2 0.7 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.2 0.5 GO:1905077 negative regulation of interleukin-17 secretion(GO:1905077)
0.2 2.0 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.2 8.3 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.2 11.7 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.2 1.8 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.2 0.9 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.2 4.9 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.2 28.2 GO:0050773 regulation of dendrite development(GO:0050773)
0.2 0.9 GO:0030576 Cajal body organization(GO:0030576)
0.2 4.2 GO:0045116 protein neddylation(GO:0045116)
0.2 5.0 GO:0016180 snRNA processing(GO:0016180)
0.2 1.7 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.2 2.1 GO:0006968 cellular defense response(GO:0006968)
0.2 0.6 GO:0046543 development of secondary sexual characteristics(GO:0045136) development of secondary female sexual characteristics(GO:0046543)
0.2 0.6 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.2 2.0 GO:0048670 regulation of collateral sprouting(GO:0048670)
0.2 1.6 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.2 2.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 0.6 GO:0015677 copper ion import(GO:0015677)
0.2 1.1 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.2 0.4 GO:0098886 modification of dendritic spine(GO:0098886)
0.2 1.7 GO:0045806 negative regulation of endocytosis(GO:0045806)
0.2 1.3 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.2 0.4 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.2 0.4 GO:0098915 membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915)
0.2 0.7 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.2 1.5 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.2 0.9 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.2 3.1 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.2 2.5 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.2 2.3 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.2 8.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.2 4.2 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.2 2.8 GO:0007019 microtubule depolymerization(GO:0007019)
0.2 3.4 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.2 2.9 GO:0060009 Sertoli cell development(GO:0060009)
0.2 3.0 GO:0006622 protein targeting to lysosome(GO:0006622)
0.2 0.7 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.2 3.6 GO:0003351 epithelial cilium movement(GO:0003351)
0.2 0.5 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.2 2.5 GO:0006491 N-glycan processing(GO:0006491)
0.2 1.9 GO:0034453 microtubule anchoring(GO:0034453)
0.2 0.9 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.2 2.8 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.2 4.0 GO:0008361 regulation of cell size(GO:0008361)
0.2 0.6 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.2 3.2 GO:0048813 dendrite morphogenesis(GO:0048813)
0.2 6.9 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107) peptidyl-threonine modification(GO:0018210)
0.2 0.9 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 3.0 GO:0016358 dendrite development(GO:0016358)
0.1 0.6 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.4 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.1 1.0 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.4 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 1.2 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.1 1.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 1.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 3.4 GO:0030851 granulocyte differentiation(GO:0030851)
0.1 1.7 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 1.4 GO:0051604 protein maturation(GO:0051604)
0.1 3.4 GO:0014037 Schwann cell differentiation(GO:0014037)
0.1 0.7 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.7 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 1.5 GO:0006110 regulation of glycolytic process(GO:0006110)
0.1 5.8 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.1 13.8 GO:0071805 potassium ion transmembrane transport(GO:0071805)
0.1 3.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 5.9 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 1.5 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.7 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1 14.8 GO:0007266 Rho protein signal transduction(GO:0007266)
0.1 9.3 GO:0019722 calcium-mediated signaling(GO:0019722)
0.1 1.0 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 3.5 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 1.0 GO:0035608 protein deglutamylation(GO:0035608)
0.1 1.4 GO:0003417 growth plate cartilage development(GO:0003417)
0.1 5.4 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 5.0 GO:0046324 regulation of glucose import(GO:0046324)
0.1 2.2 GO:0002063 chondrocyte development(GO:0002063)
0.1 0.4 GO:0051030 snRNA transport(GO:0051030)
0.1 9.0 GO:0018209 peptidyl-serine modification(GO:0018209)
0.1 1.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.8 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 4.0 GO:0042073 intraciliary transport(GO:0042073)
0.1 1.0 GO:0044539 long-chain fatty acid import(GO:0044539)
0.1 0.8 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 0.3 GO:0006953 acute-phase response(GO:0006953)
0.1 0.6 GO:0001895 retina homeostasis(GO:0001895)
0.1 0.5 GO:0006105 succinate metabolic process(GO:0006105)
0.1 1.3 GO:0043248 proteasome assembly(GO:0043248)
0.1 2.7 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 0.6 GO:0071494 cellular response to UV-C(GO:0071494)
0.1 2.1 GO:0033194 response to hydroperoxide(GO:0033194)
0.1 0.9 GO:0097120 receptor localization to synapse(GO:0097120)
0.1 0.4 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.1 0.5 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.7 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 0.8 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.6 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.8 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.1 2.6 GO:0000460 maturation of 5.8S rRNA(GO:0000460) maturation of LSU-rRNA(GO:0000470)
0.1 1.5 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 0.5 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 0.7 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 0.9 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.1 1.6 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 2.9 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.1 5.0 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.1 5.5 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.1 2.4 GO:0050688 regulation of defense response to virus(GO:0050688)
0.1 0.7 GO:0051642 centrosome localization(GO:0051642)
0.1 1.4 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.1 5.0 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 1.4 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 2.3 GO:0032091 negative regulation of protein binding(GO:0032091)
0.1 1.2 GO:0061157 mRNA destabilization(GO:0061157)
0.1 2.3 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 4.8 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 0.1 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.1 1.2 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.1 1.9 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 4.8 GO:0050770 regulation of axonogenesis(GO:0050770)
0.1 2.1 GO:0006270 DNA replication initiation(GO:0006270)
0.1 2.9 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071) regulation of metaphase/anaphase transition of cell cycle(GO:1902099)
0.1 0.7 GO:0070207 protein homotrimerization(GO:0070207)
0.1 2.4 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.1 2.7 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 2.4 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 0.6 GO:0030865 cortical cytoskeleton organization(GO:0030865)
0.1 4.0 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.1 3.1 GO:0007030 Golgi organization(GO:0007030)
0.1 2.7 GO:0050806 positive regulation of synaptic transmission(GO:0050806)
0.1 0.3 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1 2.8 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.1 0.9 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.5 GO:0097186 amelogenesis(GO:0097186)
0.0 0.3 GO:0035459 cargo loading into vesicle(GO:0035459) cargo loading into COPII-coated vesicle(GO:0090110)
0.0 3.8 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.7 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 1.6 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 0.1 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.0 0.7 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.0 0.1 GO:0010873 positive regulation of cholesterol esterification(GO:0010873)
0.0 1.3 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.2 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.0 0.4 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.3 GO:1901998 toxin transport(GO:1901998)
0.0 0.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0015809 arginine transport(GO:0015809)
0.0 0.3 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0 0.3 GO:0097576 autophagosome maturation(GO:0097352) vacuole fusion(GO:0097576)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
7.6 22.7 GO:0043512 inhibin A complex(GO:0043512)
5.8 23.2 GO:0031673 H zone(GO:0031673)
4.4 13.2 GO:0072534 perineuronal net(GO:0072534)
4.4 39.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
4.1 20.3 GO:0032437 cuticular plate(GO:0032437)
3.7 33.0 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
3.4 51.1 GO:0043083 synaptic cleft(GO:0043083)
3.0 56.4 GO:0071564 npBAF complex(GO:0071564)
2.7 11.0 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
2.7 39.8 GO:1902711 GABA-A receptor complex(GO:1902711)
2.5 42.5 GO:0031045 dense core granule(GO:0031045)
2.1 32.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
2.0 52.8 GO:0000930 gamma-tubulin complex(GO:0000930)
1.9 9.7 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
1.9 37.7 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
1.8 8.9 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
1.5 31.5 GO:0031430 M band(GO:0031430)
1.4 18.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
1.4 5.6 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
1.4 28.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
1.3 21.6 GO:0043196 varicosity(GO:0043196)
1.3 17.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
1.3 6.3 GO:0000235 astral microtubule(GO:0000235)
1.2 3.7 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
1.2 13.9 GO:0044300 cerebellar mossy fiber(GO:0044300)
1.1 16.0 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
1.1 315.6 GO:0045211 postsynaptic membrane(GO:0045211)
1.1 5.5 GO:0030425 dendrite(GO:0030425)
1.1 29.9 GO:0097458 neuron part(GO:0097458)
1.0 13.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.9 8.5 GO:0045275 respiratory chain complex III(GO:0045275)
0.9 13.7 GO:0042788 polysomal ribosome(GO:0042788)
0.9 4.5 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.9 3.6 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.9 53.4 GO:0070469 respiratory chain(GO:0070469)
0.9 9.5 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.9 25.7 GO:0032809 neuronal cell body membrane(GO:0032809)
0.8 2.5 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
0.8 3.3 GO:0001651 dense fibrillar component(GO:0001651)
0.8 3.1 GO:0008623 CHRAC(GO:0008623)
0.8 7.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.8 17.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.8 3.1 GO:0033269 internode region of axon(GO:0033269)
0.8 6.0 GO:0097165 nuclear stress granule(GO:0097165)
0.8 3.8 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.7 3.7 GO:0070826 paraferritin complex(GO:0070826)
0.7 22.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.6 8.4 GO:0097542 ciliary tip(GO:0097542)
0.6 6.4 GO:0071439 clathrin complex(GO:0071439)
0.6 5.8 GO:0044294 dendritic growth cone(GO:0044294)
0.6 1.9 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.6 12.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.5 3.5 GO:0070695 FHF complex(GO:0070695)
0.5 9.0 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.5 20.8 GO:0044295 axonal growth cone(GO:0044295)
0.5 4.8 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.5 0.9 GO:0005916 fascia adherens(GO:0005916)
0.5 3.7 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.5 7.2 GO:0042101 T cell receptor complex(GO:0042101)
0.5 1.8 GO:0031983 vesicle lumen(GO:0031983)
0.4 2.7 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.4 5.3 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.4 5.6 GO:0042581 specific granule(GO:0042581)
0.4 0.4 GO:0071438 invadopodium membrane(GO:0071438)
0.4 2.5 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.4 2.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.4 13.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.4 1.2 GO:0018444 translation release factor complex(GO:0018444)
0.4 11.9 GO:0042734 presynaptic membrane(GO:0042734)
0.4 19.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.4 1.1 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.4 6.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.4 1.1 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.3 2.8 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.3 5.6 GO:0032039 integrator complex(GO:0032039)
0.3 1.4 GO:0005726 perichromatin fibrils(GO:0005726)
0.3 3.8 GO:0005642 annulate lamellae(GO:0005642)
0.3 3.4 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.3 69.0 GO:0060076 excitatory synapse(GO:0060076)
0.3 6.4 GO:0097228 sperm principal piece(GO:0097228)
0.3 1.7 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.3 3.0 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.3 4.1 GO:1990635 proximal dendrite(GO:1990635)
0.3 3.1 GO:0030673 axolemma(GO:0030673)
0.3 1.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.3 1.5 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.3 5.6 GO:0097440 apical dendrite(GO:0097440)
0.3 2.0 GO:0071437 invadopodium(GO:0071437)
0.3 1.4 GO:0044305 calyx of Held(GO:0044305)
0.3 25.0 GO:0016605 PML body(GO:0016605)
0.3 1.9 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.3 0.8 GO:1990357 terminal web(GO:1990357)
0.3 2.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.3 31.7 GO:0030017 sarcomere(GO:0030017)
0.3 6.8 GO:0001917 photoreceptor inner segment(GO:0001917)
0.3 2.6 GO:0031595 nuclear proteasome complex(GO:0031595)
0.3 3.7 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.3 2.6 GO:0070545 PeBoW complex(GO:0070545)
0.3 26.4 GO:0016363 nuclear matrix(GO:0016363)
0.3 20.1 GO:0042641 actomyosin(GO:0042641)
0.2 3.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.2 3.2 GO:0043198 dendritic shaft(GO:0043198)
0.2 203.2 GO:0005887 integral component of plasma membrane(GO:0005887)
0.2 0.9 GO:0061702 inflammasome complex(GO:0061702)
0.2 24.3 GO:0031225 anchored component of membrane(GO:0031225)
0.2 3.0 GO:0034704 calcium channel complex(GO:0034704)
0.2 10.5 GO:0008023 transcription elongation factor complex(GO:0008023)
0.2 1.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.2 0.6 GO:0033268 node of Ranvier(GO:0033268)
0.2 22.7 GO:0036064 ciliary basal body(GO:0036064)
0.2 2.5 GO:0042588 zymogen granule(GO:0042588)
0.2 2.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.2 1.6 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.2 1.7 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 4.3 GO:0030175 filopodium(GO:0030175)
0.1 7.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 3.9 GO:0005902 microvillus(GO:0005902)
0.1 0.7 GO:0072487 MSL complex(GO:0072487)
0.1 12.4 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 0.9 GO:0015030 Cajal body(GO:0015030)
0.1 11.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 0.6 GO:0033263 CORVET complex(GO:0033263)
0.1 0.1 GO:0097487 amphisome(GO:0044753) multivesicular body, internal vesicle(GO:0097487)
0.1 1.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 2.9 GO:0035861 site of double-strand break(GO:0035861)
0.1 4.2 GO:0030054 cell junction(GO:0030054)
0.1 0.6 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1 1.3 GO:0005771 multivesicular body(GO:0005771)
0.1 4.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 1.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 1.1 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 5.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 3.4 GO:0005801 cis-Golgi network(GO:0005801)
0.1 8.7 GO:0005802 trans-Golgi network(GO:0005802)
0.1 3.9 GO:0045171 intercellular bridge(GO:0045171)
0.1 2.0 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.1 0.5 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 0.7 GO:0071565 nBAF complex(GO:0071565)
0.1 1.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 2.8 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 8.1 GO:0045202 synapse(GO:0045202)
0.1 0.3 GO:0070876 SOSS complex(GO:0070876)
0.1 2.3 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 1.6 GO:0001772 immunological synapse(GO:0001772)
0.1 0.8 GO:0097223 sperm flagellum(GO:0036126) sperm part(GO:0097223)
0.1 1.5 GO:0030117 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.1 5.9 GO:0055037 recycling endosome(GO:0055037)
0.1 1.5 GO:0034399 nuclear periphery(GO:0034399)
0.1 1.9 GO:0005871 kinesin complex(GO:0005871)
0.1 0.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 7.9 GO:0005770 late endosome(GO:0005770)
0.1 13.3 GO:0000139 Golgi membrane(GO:0000139)
0.1 2.2 GO:0008180 COP9 signalosome(GO:0008180)
0.1 0.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 3.1 GO:0005657 replication fork(GO:0005657)
0.1 0.3 GO:0097470 ribbon synapse(GO:0097470)
0.1 0.7 GO:0043235 receptor complex(GO:0043235)
0.1 4.7 GO:0032993 protein-DNA complex(GO:0032993)
0.1 1.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.9 GO:0072686 mitotic spindle(GO:0072686)
0.0 3.0 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.4 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 6.6 GO:0005635 nuclear envelope(GO:0005635)
0.0 2.3 GO:0005643 nuclear pore(GO:0005643)
0.0 2.3 GO:0000922 spindle pole(GO:0000922)
0.0 1.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.0 GO:0043195 terminal bouton(GO:0043195)
0.0 0.6 GO:0012505 endomembrane system(GO:0012505)
0.0 1.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.8 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 5.0 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 12.4 GO:0015630 microtubule cytoskeleton(GO:0015630)
0.0 18.4 GO:0005730 nucleolus(GO:0005730)
0.0 3.1 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.2 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 14.3 GO:0005794 Golgi apparatus(GO:0005794)
0.0 0.6 GO:0035371 microtubule plus-end(GO:0035371)
0.0 1.2 GO:0009986 cell surface(GO:0009986)
0.0 30.4 GO:0005886 plasma membrane(GO:0005886)
0.0 1.2 GO:0072562 blood microparticle(GO:0072562)
0.0 0.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.8 GO:0005769 early endosome(GO:0005769)
0.0 1.4 GO:0044455 mitochondrial membrane part(GO:0044455)
0.0 3.4 GO:0016607 nuclear speck(GO:0016607)
0.0 0.4 GO:0030139 endocytic vesicle(GO:0030139)
0.0 6.8 GO:0044421 extracellular region part(GO:0044421)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
8.8 35.3 GO:0030348 syntaxin-3 binding(GO:0030348)
5.7 45.3 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
5.3 42.8 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529)
5.3 31.8 GO:0070699 type II activin receptor binding(GO:0070699)
4.8 4.8 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
4.6 23.0 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
4.4 13.2 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
3.3 9.9 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
3.2 13.0 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
3.2 9.6 GO:0008502 melatonin receptor activity(GO:0008502)
3.1 24.7 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
3.1 33.6 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
3.0 21.3 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
3.0 11.9 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
3.0 56.5 GO:0035198 miRNA binding(GO:0035198)
2.8 19.9 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
2.7 10.6 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
2.6 13.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
2.5 65.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
2.4 24.5 GO:0042043 neurexin family protein binding(GO:0042043)
2.4 12.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
2.4 9.5 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
2.3 11.5 GO:0004359 glutaminase activity(GO:0004359)
2.2 11.0 GO:0050816 phosphothreonine binding(GO:0050816)
2.1 24.9 GO:0097109 neuroligin family protein binding(GO:0097109)
2.0 110.7 GO:0036002 pre-mRNA binding(GO:0036002)
2.0 32.8 GO:0004890 GABA-A receptor activity(GO:0004890)
2.0 59.0 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
1.8 7.3 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
1.7 6.6 GO:0019808 polyamine binding(GO:0019808)
1.6 6.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
1.6 14.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
1.6 6.3 GO:0098960 postsynaptic neurotransmitter receptor activity(GO:0098960)
1.6 20.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
1.5 2.9 GO:0008046 axon guidance receptor activity(GO:0008046)
1.4 4.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
1.4 37.2 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
1.4 5.6 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
1.4 4.2 GO:0016015 morphogen activity(GO:0016015)
1.4 6.9 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
1.4 17.9 GO:0045499 chemorepellent activity(GO:0045499)
1.4 4.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
1.4 24.6 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
1.4 4.1 GO:1905030 voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
1.3 13.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
1.3 66.4 GO:0046875 ephrin receptor binding(GO:0046875)
1.3 6.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
1.2 19.3 GO:0004385 guanylate kinase activity(GO:0004385)
1.2 4.8 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
1.2 14.0 GO:0050897 cobalt ion binding(GO:0050897)
1.1 10.3 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
1.1 3.3 GO:0044547 DNA topoisomerase binding(GO:0044547)
1.1 8.8 GO:0002162 dystroglycan binding(GO:0002162)
1.1 5.5 GO:0055100 adiponectin binding(GO:0055100)
1.1 39.3 GO:0070412 R-SMAD binding(GO:0070412)
1.1 8.5 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
1.0 3.1 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
1.0 59.7 GO:0030507 spectrin binding(GO:0030507)
1.0 3.1 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
1.0 2.0 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
1.0 20.7 GO:0030506 ankyrin binding(GO:0030506)
1.0 17.6 GO:0005540 hyaluronic acid binding(GO:0005540)
1.0 2.9 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.9 6.3 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.9 2.7 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.9 15.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.9 4.3 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.9 4.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.9 12.0 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.8 24.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.8 4.9 GO:0033142 progesterone receptor binding(GO:0033142)
0.8 3.2 GO:0099528 G-protein coupled neurotransmitter receptor activity(GO:0099528)
0.8 2.4 GO:0071568 UFM1 transferase activity(GO:0071568)
0.8 2.3 GO:0004111 creatine kinase activity(GO:0004111)
0.8 15.6 GO:0043422 protein kinase B binding(GO:0043422)
0.8 10.9 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.8 3.9 GO:0070700 BMP receptor binding(GO:0070700)
0.8 3.8 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.8 3.0 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.7 21.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.7 23.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.6 19.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.6 10.7 GO:0030275 LRR domain binding(GO:0030275)
0.6 10.0 GO:0046625 sphingolipid binding(GO:0046625)
0.6 3.7 GO:0005112 Notch binding(GO:0005112)
0.6 18.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.6 17.2 GO:0017091 AU-rich element binding(GO:0017091)
0.6 2.3 GO:0050733 RS domain binding(GO:0050733)
0.6 2.2 GO:0001847 opsonin receptor activity(GO:0001847)
0.6 2.8 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.6 2.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.6 5.0 GO:0005523 tropomyosin binding(GO:0005523)
0.5 3.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.5 3.7 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.5 2.7 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.5 1.6 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.5 16.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.5 7.7 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.5 3.5 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.5 1.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.5 1.9 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.5 2.8 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.5 3.7 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.5 1.4 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.5 1.8 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.4 1.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.4 1.8 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.4 2.2 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.4 4.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.4 12.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.4 9.2 GO:0031489 myosin V binding(GO:0031489)
0.4 3.3 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.4 2.9 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.4 3.7 GO:0048185 activin binding(GO:0048185)
0.4 22.2 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.4 69.7 GO:0005516 calmodulin binding(GO:0005516)
0.4 2.0 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.4 2.8 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.4 4.3 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.4 0.8 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.4 19.1 GO:0005262 calcium channel activity(GO:0005262)
0.4 3.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.4 2.6 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.4 5.8 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.4 9.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.4 1.4 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.4 2.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.4 3.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.4 3.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.3 1.0 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.3 1.0 GO:0070052 collagen V binding(GO:0070052)
0.3 4.0 GO:0004000 adenosine deaminase activity(GO:0004000)
0.3 30.5 GO:0005057 receptor signaling protein activity(GO:0005057)
0.3 0.7 GO:0061665 SUMO ligase activity(GO:0061665)
0.3 9.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.3 4.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.3 33.0 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.3 2.9 GO:0030274 LIM domain binding(GO:0030274)
0.3 2.5 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.3 0.9 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.3 34.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.3 1.2 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.3 0.9 GO:0070140 isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140)
0.3 1.7 GO:0004984 olfactory receptor activity(GO:0004984)
0.3 8.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.3 1.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.3 2.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.3 6.7 GO:0042287 MHC protein binding(GO:0042287)
0.3 1.7 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.3 6.3 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.3 12.0 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.3 3.8 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.3 1.9 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.3 1.8 GO:0034056 estrogen response element binding(GO:0034056)
0.3 3.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.3 2.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.3 2.8 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.2 2.5 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
0.2 1.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 1.5 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.2 0.7 GO:0048019 receptor antagonist activity(GO:0048019)
0.2 7.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 6.0 GO:0071889 14-3-3 protein binding(GO:0071889)
0.2 1.1 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 4.7 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.2 3.5 GO:0008143 poly(A) binding(GO:0008143)
0.2 8.6 GO:0019894 kinesin binding(GO:0019894)
0.2 2.4 GO:0017166 vinculin binding(GO:0017166)
0.2 3.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2 4.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.2 7.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.2 47.6 GO:0008017 microtubule binding(GO:0008017)
0.2 1.7 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.2 4.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.2 1.7 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.2 5.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 2.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 4.6 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.2 1.8 GO:0001972 retinoic acid binding(GO:0001972)
0.2 14.1 GO:0030674 protein binding, bridging(GO:0030674)
0.2 48.1 GO:0005096 GTPase activator activity(GO:0005096)
0.2 0.6 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.2 1.1 GO:0001515 opioid peptide activity(GO:0001515)
0.2 3.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.2 1.2 GO:0031419 cobalamin binding(GO:0031419)
0.2 1.4 GO:0015197 peptide transporter activity(GO:0015197)
0.2 6.8 GO:0048365 Rac GTPase binding(GO:0048365)
0.2 0.5 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.2 1.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.2 0.8 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.2 1.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.2 3.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.2 2.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 2.4 GO:0042805 actinin binding(GO:0042805)
0.2 1.6 GO:0015464 acetylcholine receptor activity(GO:0015464) acetylcholine-gated cation channel activity(GO:0022848)
0.2 0.6 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.2 1.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.2 5.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 10.2 GO:0017137 Rab GTPase binding(GO:0017137)
0.2 27.2 GO:0042277 peptide binding(GO:0042277)
0.1 1.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 3.3 GO:0050681 androgen receptor binding(GO:0050681)
0.1 1.2 GO:0008417 fucosyltransferase activity(GO:0008417)
0.1 101.4 GO:0042803 protein homodimerization activity(GO:0042803)
0.1 1.7 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 45.6 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.1 5.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 2.7 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.3 GO:0051378 serotonin binding(GO:0051378)
0.1 0.4 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.1 0.6 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 6.0 GO:0015631 tubulin binding(GO:0015631)
0.1 5.0 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.1 2.3 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 16.2 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 1.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 2.1 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.5 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.7 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1 3.2 GO:0001671 ATPase activator activity(GO:0001671)
0.1 5.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 2.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 1.3 GO:0005537 mannose binding(GO:0005537)
0.1 0.9 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 7.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 3.0 GO:0015485 cholesterol binding(GO:0015485)
0.1 1.9 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.1 1.5 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 3.3 GO:0003678 DNA helicase activity(GO:0003678)
0.1 2.1 GO:0019905 syntaxin binding(GO:0019905)
0.1 1.9 GO:0030515 snoRNA binding(GO:0030515)
0.1 7.4 GO:0004386 helicase activity(GO:0004386)
0.1 0.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.0 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 2.2 GO:0032947 protein complex scaffold(GO:0032947)
0.1 0.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 0.4 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.8 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 1.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 3.8 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.1 0.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.4 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 11.4 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.1 1.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 1.0 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.0 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 1.7 GO:0008144 drug binding(GO:0008144)
0.0 0.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 4.5 GO:0030246 carbohydrate binding(GO:0030246)
0.0 1.7 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 1.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.4 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.9 GO:0008374 O-acyltransferase activity(GO:0008374)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 1.5 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 0.5 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.3 GO:0048306 calcium-dependent protein binding(GO:0048306)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 66.6 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
1.2 64.0 PID_REELIN_PATHWAY Reelin signaling pathway
1.0 18.0 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.8 26.0 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.7 11.7 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.7 25.9 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.7 16.7 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.7 18.1 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.6 20.1 PID_ALK1_PATHWAY ALK1 signaling events
0.6 60.0 PID_CMYB_PATHWAY C-MYB transcription factor network
0.6 25.8 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.6 15.6 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.5 33.9 PID_LKB1_PATHWAY LKB1 signaling events
0.5 13.2 PID_IL3_PATHWAY IL3-mediated signaling events
0.5 1.5 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.5 5.4 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.5 7.2 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.4 7.6 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.4 11.9 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.4 18.2 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.4 5.9 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.4 2.5 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.4 17.3 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.4 4.5 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.4 9.9 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.4 10.2 PID_MYC_PATHWAY C-MYC pathway
0.4 6.8 PID_CDC42_PATHWAY CDC42 signaling events
0.3 9.8 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.3 1.6 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.3 8.2 PID_IL4_2PATHWAY IL4-mediated signaling events
0.3 11.3 PID_BMP_PATHWAY BMP receptor signaling
0.3 14.8 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.3 7.2 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.3 3.3 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.3 3.5 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.3 3.4 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.3 3.9 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.3 16.9 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.3 3.3 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.2 3.6 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.2 4.5 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.2 2.5 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.2 4.2 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.2 2.1 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling
0.2 6.0 PID_FGF_PATHWAY FGF signaling pathway
0.2 6.1 PID_TNF_PATHWAY TNF receptor signaling pathway
0.2 7.3 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.2 1.8 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.1 3.1 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.1 5.7 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.1 4.5 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 4.5 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 0.8 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 13.2 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.2 PID_ARF6_PATHWAY Arf6 signaling events
0.1 0.6 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.1 1.3 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP
0.1 1.3 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.1 0.6 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 0.4 PID_RAC1_PATHWAY RAC1 signaling pathway
0.1 2.6 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.1 1.5 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 0.7 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 1.6 ST_INTEGRIN_SIGNALING_PATHWAY Integrin Signaling Pathway
0.0 0.2 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 0.1 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
5.7 22.7 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
3.4 34.4 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
2.7 51.3 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
2.2 59.8 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
2.2 70.6 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
2.0 75.1 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
1.8 65.1 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
1.4 2.9 REACTOME_SIGNALLING_BY_NGF Genes involved in Signalling by NGF
1.3 17.9 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
1.2 16.1 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
1.2 27.9 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
1.2 41.5 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
1.1 12.6 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.9 21.3 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.8 0.8 REACTOME_INCRETIN_SYNTHESIS_SECRETION_AND_INACTIVATION Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.8 10.5 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.7 2.1 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.7 13.2 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.7 8.8 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.7 48.2 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.6 15.9 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.6 22.9 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.6 24.5 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.6 17.1 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.5 4.8 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.5 15.1 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.5 6.3 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.5 18.1 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.5 5.1 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.5 11.0 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.5 9.9 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.4 1.7 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.4 11.7 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.4 1.3 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.4 5.0 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.4 5.4 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.4 30.1 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.4 3.8 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.4 2.2 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.4 4.3 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.3 8.8 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.3 2.7 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.3 12.3 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.3 2.8 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.3 8.4 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.3 4.3 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.3 2.1 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.3 11.0 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.2 23.5 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2 1.4 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2 3.3 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.2 2.1 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.2 2.6 REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.2 1.9 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.2 1.4 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.2 1.8 REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.2 1.6 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.2 3.2 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 3.0 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 22.9 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.2 2.5 REACTOME_FORMATION_OF_TRANSCRIPTION_COUPLED_NER_TC_NER_REPAIR_COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.2 12.3 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.2 2.9 REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ Genes involved in Cyclin E associated events during G1/S transition
0.2 3.3 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.1 3.5 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.1 3.0 REACTOME_REGULATORY_RNA_PATHWAYS Genes involved in Regulatory RNA pathways
0.1 0.5 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 0.3 REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 0.9 REACTOME_SIGNALING_BY_ACTIVATED_POINT_MUTANTS_OF_FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 1.5 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 1.0 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.1 11.6 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.1 5.2 REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.1 3.4 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 3.5 REACTOME_ION_CHANNEL_TRANSPORT Genes involved in Ion channel transport
0.1 2.3 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 1.6 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.1 1.4 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.1 0.8 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 1.3 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 0.6 REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS Genes involved in Prolonged ERK activation events
0.1 0.9 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 0.7 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.1 1.4 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 0.7 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 2.9 REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 3.0 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.3 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.9 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.4 REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.1 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.0 1.0 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.0 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.4 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.1 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol