Motif ID: Hoxc6

Z-value: 0.375


Transcription factors associated with Hoxc6:

Gene SymbolEntrez IDGene Name
Hoxc6 ENSMUSG00000001661.4 Hoxc6



Activity profile for motif Hoxc6.

activity profile for motif Hoxc6


Sorted Z-values histogram for motif Hoxc6

Sorted Z-values for motif Hoxc6



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxc6

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_17574268 1.213 ENSMUST00000030568.7
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr7_-_115846080 0.890 ENSMUST00000166207.1
Sox6
SRY-box containing gene 6
chr15_-_50889043 0.830 ENSMUST00000183997.1
ENSMUST00000183757.1
Trps1

trichorhinophalangeal syndrome I (human)

chr3_+_5218546 0.758 ENSMUST00000026284.6
Zfhx4
zinc finger homeodomain 4
chr10_+_61175206 0.701 ENSMUST00000079235.5
Tbata
thymus, brain and testes associated
chr3_+_5218516 0.669 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chrM_+_14138 0.657 ENSMUST00000082421.1
mt-Cytb
mitochondrially encoded cytochrome b
chr7_+_123123870 0.654 ENSMUST00000094053.5
Tnrc6a
trinucleotide repeat containing 6a
chr11_-_23895208 0.648 ENSMUST00000102863.2
ENSMUST00000020513.3
Papolg

poly(A) polymerase gamma

chr5_-_110046486 0.577 ENSMUST00000167969.1
Gm17655
predicted gene, 17655
chr3_+_66985680 0.542 ENSMUST00000065047.6
Rsrc1
arginine/serine-rich coiled-coil 1
chrM_-_14060 0.541 ENSMUST00000082419.1
mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chrX_-_143933204 0.527 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr8_-_9976294 0.527 ENSMUST00000095476.4
Lig4
ligase IV, DNA, ATP-dependent
chr10_-_100589205 0.498 ENSMUST00000054471.8
4930430F08Rik
RIKEN cDNA 4930430F08 gene
chr15_-_50889691 0.476 ENSMUST00000165201.2
ENSMUST00000184458.1
Trps1

trichorhinophalangeal syndrome I (human)

chr9_-_27155418 0.474 ENSMUST00000167074.1
ENSMUST00000034472.8
Jam3

junction adhesion molecule 3

chr3_-_113574242 0.445 ENSMUST00000142505.2
Amy1
amylase 1, salivary
chr17_-_78985428 0.443 ENSMUST00000118991.1
Prkd3
protein kinase D3
chr11_-_109472611 0.436 ENSMUST00000168740.1
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr3_+_5218589 0.423 ENSMUST00000177488.1
Zfhx4
zinc finger homeodomain 4
chr17_-_35115428 0.421 ENSMUST00000172854.1
ENSMUST00000062657.4
Ly6g5b

lymphocyte antigen 6 complex, locus G5B

chrX_-_94212638 0.399 ENSMUST00000113922.1
Eif2s3x
eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked
chr6_+_128399881 0.386 ENSMUST00000120405.1
Nrip2
nuclear receptor interacting protein 2
chrX_-_143933089 0.379 ENSMUST00000087313.3
Dcx
doublecortin
chrX_-_94212685 0.370 ENSMUST00000050328.8
Eif2s3x
eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked
chr2_-_51149100 0.346 ENSMUST00000154545.1
ENSMUST00000017288.2
Rnd3

Rho family GTPase 3

chr15_+_44619551 0.344 ENSMUST00000022964.7
Ebag9
estrogen receptor-binding fragment-associated gene 9
chr6_+_128399766 0.323 ENSMUST00000001561.5
Nrip2
nuclear receptor interacting protein 2
chr6_-_65144908 0.269 ENSMUST00000031982.4
Hpgds
hematopoietic prostaglandin D synthase
chr16_-_21995478 0.260 ENSMUST00000074230.4
ENSMUST00000060673.6
Liph

lipase, member H

chr15_+_100154379 0.249 ENSMUST00000023768.6
ENSMUST00000108971.2
Dip2b

DIP2 disco-interacting protein 2 homolog B (Drosophila)

chr9_-_21760275 0.242 ENSMUST00000098942.4
Spc24
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr1_-_191907527 0.242 ENSMUST00000069573.5
1700034H15Rik
RIKEN cDNA 1700034H15 gene
chr3_+_66985700 0.231 ENSMUST00000046542.6
ENSMUST00000162693.1
Rsrc1

arginine/serine-rich coiled-coil 1

chr10_+_37139558 0.224 ENSMUST00000062667.3
5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr13_+_93304066 0.204 ENSMUST00000109493.1
Homer1
homer homolog 1 (Drosophila)
chr8_-_54724317 0.203 ENSMUST00000129132.2
ENSMUST00000150488.1
ENSMUST00000127511.2
Wdr17


WD repeat domain 17


chr10_-_53647080 0.194 ENSMUST00000169866.1
Fam184a
family with sequence similarity 184, member A
chr19_+_11469353 0.185 ENSMUST00000165310.1
Ms4a6c
membrane-spanning 4-domains, subfamily A, member 6C
chr1_-_22315792 0.138 ENSMUST00000164877.1
Rims1
regulating synaptic membrane exocytosis 1
chr11_-_26210553 0.137 ENSMUST00000101447.3
5730522E02Rik
RIKEN cDNA 5730522E02 gene
chr3_+_136670076 0.136 ENSMUST00000070198.7
Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr3_+_66985647 0.129 ENSMUST00000162362.1
ENSMUST00000065074.7
Rsrc1

arginine/serine-rich coiled-coil 1

chr7_-_19604444 0.117 ENSMUST00000086041.5
Clasrp
CLK4-associating serine/arginine rich protein
chr8_-_109962127 0.115 ENSMUST00000001722.7
ENSMUST00000051430.6
Marveld3

MARVEL (membrane-associating) domain containing 3

chr7_+_5020376 0.105 ENSMUST00000076251.4
Zfp865
zinc finger protein 865
chr13_+_93304799 0.101 ENSMUST00000080127.5
Homer1
homer homolog 1 (Drosophila)
chr4_+_144893127 0.093 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr8_-_54724474 0.089 ENSMUST00000175915.1
Wdr17
WD repeat domain 17
chr5_-_23616528 0.081 ENSMUST00000088392.4
Srpk2
serine/arginine-rich protein specific kinase 2
chr1_-_43827751 0.071 ENSMUST00000128261.1
ENSMUST00000126008.1
ENSMUST00000139451.1
Uxs1


UDP-glucuronate decarboxylase 1


chr3_+_151437887 0.064 ENSMUST00000046977.7
Eltd1
EGF, latrophilin seven transmembrane domain containing 1
chr19_+_32619997 0.064 ENSMUST00000025833.6
Papss2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr6_-_3494587 0.033 ENSMUST00000049985.8
Hepacam2
HEPACAM family member 2
chr10_-_58718210 0.023 ENSMUST00000169859.1
Gm17542
predicted gene, 17542
chr7_-_16285454 0.020 ENSMUST00000174270.1
Ccdc9
coiled-coil domain containing 9
chr15_+_91673175 0.004 ENSMUST00000060642.6
Lrrk2
leucine-rich repeat kinase 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 0.7 GO:0033762 response to glucagon(GO:0033762)
0.1 0.5 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.1 0.9 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1 0.4 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 0.9 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.3 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.5 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.1 1.3 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.1 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) regulation of connective tissue replacement(GO:1905203)
0.0 0.7 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.1 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.0 0.3 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.0 0.9 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.1 GO:0034035 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.6 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.1 GO:1902414 protein localization to cell junction(GO:1902414)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.1 0.8 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.5 GO:0033010 paranodal junction(GO:0033010)
0.1 0.7 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 0.7 GO:0045275 respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.1 1.2 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.6 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.5 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 0.7 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.3 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.7 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.3 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.4 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.4 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 0.9 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.5 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME_INTEGRATION_OF_PROVIRUS Genes involved in Integration of provirus
0.0 0.7 REACTOME_REGULATORY_RNA_PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.1 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle