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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr7_-_141010759	3.707	ENSMUST00000026565.6	Ifitm3	interferon induced transmembrane protein 3
chr17_-_6782775	2.212	ENSMUST00000064234.6	Ezr	ezrin
chr11_+_88999376	1.588	ENSMUST00000100627.2 ENSMUST00000107896.3 ENSMUST00000000284.6	Trim25	tripartite motif-containing 25
chr6_-_39118211	1.398	ENSMUST00000038398.6	Parp12	poly (ADP-ribose) polymerase family, member 12
chr2_-_77519565	1.175	ENSMUST00000111830.2	Zfp385b	zinc finger protein 385B
chr16_+_35938972	1.165	ENSMUST00000023622.6 ENSMUST00000114877.1	Parp9	poly (ADP-ribose) polymerase family, member 9
chr4_-_40239779	1.133	ENSMUST00000037907.6	Ddx58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr3_+_138065052	1.029	ENSMUST00000163080.2	1110002E22Rik	RIKEN cDNA 1110002E22 gene
chr19_+_55741810	0.980	ENSMUST00000111657.3 ENSMUST00000061496.9 ENSMUST00000041717.7 ENSMUST00000111662.4	Tcf7l2	transcription factor 7 like 2, T cell specific, HMG box
chr17_+_34203527	0.974	ENSMUST00000025197.5	Tap2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr7_+_128523576	0.918	ENSMUST00000033136.7	Bag3	BCL2-associated athanogene 3
chr4_-_40239700	0.872	ENSMUST00000142055.1	Ddx58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr7_-_141266415	0.738	ENSMUST00000106023.1 ENSMUST00000097952.2 ENSMUST00000026571.4	Irf7	interferon regulatory factor 7
chr16_-_35871544	0.722	ENSMUST00000042665.8	Parp14	poly (ADP-ribose) polymerase family, member 14
chr3_-_142395661	0.595	ENSMUST00000029941.9 ENSMUST00000168967.2 ENSMUST00000090134.5 ENSMUST00000058626.8	Pdlim5	PDZ and LIM domain 5
chr1_-_163313661	0.594	ENSMUST00000174397.1 ENSMUST00000075805.6 ENSMUST00000027878.7	Prrx1	paired related homeobox 1
chr3_+_142496924	0.591	ENSMUST00000090127.2	Gbp5	guanylate binding protein 5
chr1_-_184732616	0.516	ENSMUST00000048572.6	Hlx	H2.0-like homeobox
chr16_+_35938470	0.512	ENSMUST00000114878.1	Parp9	poly (ADP-ribose) polymerase family, member 9
chr11_-_78984831	0.466	ENSMUST00000073001.4 ENSMUST00000108269.3	Lgals9	lectin, galactose binding, soluble 9
chr11_-_78984946	0.415	ENSMUST00000108268.3	Lgals9	lectin, galactose binding, soluble 9
chr11_+_101582236	0.361	ENSMUST00000039581.7 ENSMUST00000100403.2 ENSMUST00000107194.1 ENSMUST00000128614.1	Tmem106a	transmembrane protein 106A
chr15_-_76243401	0.343	ENSMUST00000165738.1 ENSMUST00000075689.6	Parp10	poly (ADP-ribose) polymerase family, member 10
chr15_+_96287518	0.300	ENSMUST00000134985.2 ENSMUST00000096250.4	Arid2	AT rich interactive domain 2 (ARID, RFX-like)
chr6_+_57580992	0.274	ENSMUST00000031817.8	Herc6	hect domain and RLD 6
chr12_-_31950170	0.259	ENSMUST00000176520.1	Hbp1	high mobility group box transcription factor 1
chr16_-_5255923	0.255	ENSMUST00000139584.1 ENSMUST00000064635.5	Fam86	family with sequence similarity 86
chr12_-_31950210	0.255	ENSMUST00000176084.1 ENSMUST00000176103.1 ENSMUST00000167458.2	Hbp1	high mobility group box transcription factor 1
chr5_+_99979061	0.249	ENSMUST00000046721.1	4930524J08Rik	RIKEN cDNA 4930524J08 gene
chr11_+_72689997	0.247	ENSMUST00000155998.1	Ankfy1	ankyrin repeat and FYVE domain containing 1
chrX_+_77511002	0.242	ENSMUST00000088217.5	Tbl1x	transducin (beta)-like 1 X-linked
chr11_+_60699758	0.218	ENSMUST00000108719.3	Llgl1	lethal giant larvae homolog 1 (Drosophila)
chr9_+_95954744	0.211	ENSMUST00000034981.7	Xrn1	5'-3' exoribonuclease 1
chr2_-_69586021	0.209	ENSMUST00000100051.2 ENSMUST00000092551.4 ENSMUST00000080953.5	Lrp2	low density lipoprotein receptor-related protein 2
chr5_+_92809372	0.199	ENSMUST00000113054.2	Shroom3	shroom family member 3
chr16_-_55838827	0.195	ENSMUST00000096026.2 ENSMUST00000036273.6 ENSMUST00000114457.1	Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta
chr9_-_111057235	0.194	ENSMUST00000111888.1	Ccrl2	chemokine (C-C motif) receptor-like 2
chr2_-_77170592	0.180	ENSMUST00000164114.2 ENSMUST00000049544.7	Ccdc141	coiled-coil domain containing 141
chr9_-_123851855	0.180	ENSMUST00000184082.1 ENSMUST00000167595.2	Fyco1	FYVE and coiled-coil domain containing 1
chr7_+_49246131	0.178	ENSMUST00000064395.6	Nav2	neuron navigator 2
chr7_-_65370908	0.178	ENSMUST00000032729.6	Tjp1	tight junction protein 1
chr16_-_35939082	0.176	ENSMUST00000081933.7 ENSMUST00000114885.1	Dtx3l	deltex 3-like (Drosophila)
chr6_-_13608011	0.170	ENSMUST00000031554.2	Tmem168	transmembrane protein 168
chr12_+_26469204	0.170	ENSMUST00000020969.3	Cmpk2	cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr11_+_60699718	0.167	ENSMUST00000052346.3	Llgl1	lethal giant larvae homolog 1 (Drosophila)
chr10_+_80249441	0.164	ENSMUST00000020361.6	Ndufs7	NADH dehydrogenase (ubiquinone) Fe-S protein 7
chr10_+_80249106	0.163	ENSMUST00000105364.1	Ndufs7	NADH dehydrogenase (ubiquinone) Fe-S protein 7
chr4_-_136886187	0.159	ENSMUST00000046384.8	C1qb	complement component 1, q subcomponent, beta polypeptide
chr9_+_55326913	0.155	ENSMUST00000085754.3 ENSMUST00000034862.4	AI118078	expressed sequence AI118078
chrM_+_8600	0.147	ENSMUST00000082409.1	mt-Co3	mitochondrially encoded cytochrome c oxidase III
chr4_+_108460000	0.127	ENSMUST00000097925.2	Zcchc11	zinc finger, CCHC domain containing 11
chr6_-_87838671	0.118	ENSMUST00000089497.4	Isy1	ISY1 splicing factor homolog (S. cerevisiae)
chr1_+_52119438	0.100	ENSMUST00000070968.7	Stat1	signal transducer and activator of transcription 1
chr16_+_23609895	0.072	ENSMUST00000038423.5	Rtp4	receptor transporter protein 4
chr8_-_105568298	0.065	ENSMUST00000005849.5	Agrp	agouti related protein
chr12_-_73113407	0.064	ENSMUST00000175693.1	Six4	sine oculis-related homeobox 4
chr9_+_57072024	0.034	ENSMUST00000169879.1	Sin3a	transcriptional regulator, SIN3A (yeast)
chr1_-_105356658	0.025	ENSMUST00000058688.5 ENSMUST00000172299.1	Rnf152	ring finger protein 152
chr11_-_86201144	0.019	ENSMUST00000044423.3	Brip1	BRCA1 interacting protein C-terminal helicase 1
chr16_-_67620805	0.013	ENSMUST00000120594.1	Cadm2	cell adhesion molecule 2
chr15_+_9436028	0.003	ENSMUST00000042360.3	Capsl	calcyphosine-like

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.2	GO:1900041	intestinal D-glucose absorption(GO:0001951) negative regulation of interleukin-2 secretion(GO:1900041) terminal web assembly(GO:1902896)
0.5	2.0	GO:0009597	detection of virus(GO:0009597)
0.3	1.0	GO:0002489	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489)
0.3	0.9	GO:1902714	negative regulation of interferon-gamma secretion(GO:1902714)
0.3	5.3	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
0.3	1.1	GO:0070212	protein poly-ADP-ribosylation(GO:0070212)
0.2	1.7	GO:0060330	regulation of response to interferon-gamma(GO:0060330)
0.1	0.7	GO:0034124	regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.1	1.0	GO:0048625	myoblast fate commitment(GO:0048625)
0.1	0.6	GO:0032621	interleukin-18 production(GO:0032621)
0.1	0.5	GO:0045629	positive regulation of T-helper 1 cell differentiation(GO:0045627) negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1	0.2	GO:0046077	dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.1	0.5	GO:0010745	negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.1	0.9	GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0	0.6	GO:0048664	neuron fate determination(GO:0048664)
0.0	0.2	GO:1901098	positive regulation of autophagosome maturation(GO:1901098)
0.0	0.2	GO:0021564	glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.0	0.2	GO:0032439	endosome localization(GO:0032439) positive regulation of pinocytosis(GO:0048549)
0.0	0.1	GO:0000389	generation of catalytic spliceosome for second transesterification step(GO:0000350) mRNA 3'-splice site recognition(GO:0000389)
0.0	0.4	GO:0035090	maintenance of apical/basal cell polarity(GO:0035090)
0.0	0.1	GO:0034239	regulation of macrophage fusion(GO:0034239)
0.0	0.1	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.3	GO:0060982	coronary artery morphogenesis(GO:0060982)
0.0	0.1	GO:0008582	regulation of synaptic growth at neuromuscular junction(GO:0008582) skeletal muscle fiber differentiation(GO:0098528)
0.0	0.2	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0	0.2	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.0	0.6	GO:0003301	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.2	GO:0044872	lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0	0.0	GO:1901675	negative regulation of histone H3-K27 acetylation(GO:1901675)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.2	GO:0098592	cytoplasmic side of apical plasma membrane(GO:0098592)
0.1	1.0	GO:0042825	TAP complex(GO:0042825)
0.1	1.0	GO:0070369	beta-catenin-TCF7L2 complex(GO:0070369)
0.0	0.2	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
0.0	0.4	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	2.0	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.1	GO:0071012	catalytic step 1 spliceosome(GO:0071012)
0.0	0.2	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0005796	Golgi lumen(GO:0005796)
0.0	4.0	GO:0045177	apical part of cell(GO:0045177)
0.0	1.5	GO:0030018	Z disc(GO:0030018)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.0	GO:0015433	peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.2	4.1	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2	2.2	GO:0044548	S100 protein binding(GO:0044548)
0.1	0.9	GO:0016936	galactoside binding(GO:0016936)
0.1	0.9	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.1	1.6	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1	0.2	GO:0004534	5'-3' exoribonuclease activity(GO:0004534)
0.1	0.2	GO:0042954	lipoprotein transporter activity(GO:0042954)
0.1	0.2	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.1	0.2	GO:0004127	cytidylate kinase activity(GO:0004127) uridylate kinase activity(GO:0009041)
0.0	1.0	GO:0070016	gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.0	0.6	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0	0.1	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	1.9	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.3	GO:0048038	quinone binding(GO:0048038)
0.0	0.2	GO:0071253	connexin binding(GO:0071253)
0.0	0.6	GO:0071837	HMG box domain binding(GO:0071837)
0.0	1.2	GO:0002039	p53 binding(GO:0002039)
0.0	0.1	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.2	PID_SYNDECAN_2_PATHWAY	Syndecan-2-mediated signaling events
0.0	0.5	PID_MYC_PATHWAY	C-MYC pathway
0.0	0.6	PID_IL12_2PATHWAY	IL12-mediated signaling events
0.0	1.0	PID_AP1_PATHWAY	AP-1 transcription factor network
0.0	0.7	PID_IL4_2PATHWAY	IL4-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	4.3	REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.1	3.5	REACTOME_INTERFERON_ALPHA_BETA_SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	1.0	REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	2.2	REACTOME_RECYCLING_PATHWAY_OF_L1	Genes involved in Recycling pathway of L1
0.0	0.2	REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.2	REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.6	REACTOME_INTERFERON_GAMMA_SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.2	REACTOME_STEROID_HORMONES	Genes involved in Steroid hormones
0.0	0.2	REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease

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