Motif ID: Meis2

Z-value: 0.997


Transcription factors associated with Meis2:

Gene SymbolEntrez IDGene Name
Meis2 ENSMUSG00000027210.14 Meis2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Meis2mm10_v2_chr2_-_116065047_116065133-0.315.0e-02Click!


Activity profile for motif Meis2.

activity profile for motif Meis2


Sorted Z-values histogram for motif Meis2

Sorted Z-values for motif Meis2



Network of associatons between targets according to the STRING database.



First level regulatory network of Meis2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_49822710 12.213 ENSMUST00000031843.6
Npy
neuropeptide Y
chr3_-_82074639 8.274 ENSMUST00000029635.8
Gucy1b3
guanylate cyclase 1, soluble, beta 3
chr19_-_57197556 6.814 ENSMUST00000099294.2
Ablim1
actin-binding LIM protein 1
chr19_-_57197496 6.540 ENSMUST00000111544.1
Ablim1
actin-binding LIM protein 1
chr19_-_57197377 6.485 ENSMUST00000111546.1
Ablim1
actin-binding LIM protein 1
chr19_-_57197435 6.452 ENSMUST00000111550.1
Ablim1
actin-binding LIM protein 1
chr4_+_42922253 4.958 ENSMUST00000139100.1
N28178
expressed sequence N28178
chr9_+_120539801 4.476 ENSMUST00000047687.7
Entpd3
ectonucleoside triphosphate diphosphohydrolase 3
chr9_+_53771499 4.334 ENSMUST00000048670.8
Slc35f2
solute carrier family 35, member F2
chr9_-_63711969 4.274 ENSMUST00000154323.1
Smad3
SMAD family member 3
chr2_+_71981184 4.240 ENSMUST00000090826.5
ENSMUST00000102698.3
Rapgef4

Rap guanine nucleotide exchange factor (GEF) 4

chr6_-_106800051 4.047 ENSMUST00000013882.7
ENSMUST00000049675.4
ENSMUST00000113239.3
Crbn


cereblon


chr2_+_158667119 4.037 ENSMUST00000045503.4
Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr19_-_19001099 4.016 ENSMUST00000040153.8
ENSMUST00000112828.1
Rorb

RAR-related orphan receptor beta

chr5_-_100159261 3.793 ENSMUST00000139520.1
Tmem150c
transmembrane protein 150C
chr2_+_158666690 3.762 ENSMUST00000103116.3
Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr18_+_36939178 3.683 ENSMUST00000115662.2
Pcdha2
protocadherin alpha 2
chr7_+_48959089 3.664 ENSMUST00000183659.1
Nav2
neuron navigator 2
chr4_+_128058962 3.591 ENSMUST00000184063.1
Csmd2
CUB and Sushi multiple domains 2
chr3_+_134828993 3.527 ENSMUST00000029822.4
Tacr3
tachykinin receptor 3
chr17_+_26202946 3.448 ENSMUST00000122058.1
ENSMUST00000025020.5
Rgs11

regulator of G-protein signaling 11

chr19_+_42247544 3.347 ENSMUST00000122375.1
Golga7b
golgi autoantigen, golgin subfamily a, 7B
chr9_+_106448629 3.323 ENSMUST00000048527.7
Abhd14b
abhydrolase domain containing 14b
chr13_-_41079628 3.243 ENSMUST00000165087.1
ENSMUST00000070193.6
Mak

male germ cell-associated kinase

chr5_-_109558957 3.229 ENSMUST00000044579.7
Crlf2
cytokine receptor-like factor 2
chr6_-_136941494 3.026 ENSMUST00000111892.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr1_-_193370260 2.824 ENSMUST00000016323.4
Camk1g
calcium/calmodulin-dependent protein kinase I gamma
chr19_+_55253369 2.796 ENSMUST00000043150.4
Acsl5
acyl-CoA synthetase long-chain family member 5
chr12_-_27160311 2.787 ENSMUST00000182473.1
ENSMUST00000177636.1
ENSMUST00000183238.1
Gm9866


predicted gene 9866


chr15_-_89128634 2.729 ENSMUST00000082197.5
Hdac10
histone deacetylase 10
chr13_+_5861489 2.680 ENSMUST00000000080.6
Klf6
Kruppel-like factor 6
chr16_-_23890805 2.655 ENSMUST00000004480.3
Sst
somatostatin
chr7_+_3303503 2.649 ENSMUST00000100301.4
Prkcg
protein kinase C, gamma
chr7_+_144175513 2.603 ENSMUST00000105900.1
Shank2
SH3/ankyrin domain gene 2
chr17_+_8924109 2.602 ENSMUST00000149440.1
Pde10a
phosphodiesterase 10A
chr9_-_114933811 2.465 ENSMUST00000084853.3
Gpd1l
glycerol-3-phosphate dehydrogenase 1-like
chr1_-_52817503 2.465 ENSMUST00000162576.1
Inpp1
inositol polyphosphate-1-phosphatase
chr1_+_33669816 2.452 ENSMUST00000051203.5
1700001G17Rik
RIKEN cDNA 1700001G17 gene
chr7_+_19176416 2.436 ENSMUST00000117338.1
Eml2
echinoderm microtubule associated protein like 2
chr13_-_49320219 2.386 ENSMUST00000110086.1
Fgd3
FYVE, RhoGEF and PH domain containing 3
chr11_+_101155884 2.371 ENSMUST00000043654.9
Tubg2
tubulin, gamma 2
chr10_+_107271827 2.325 ENSMUST00000020057.8
ENSMUST00000105280.3
Lin7a

lin-7 homolog A (C. elegans)

chr3_-_127499095 2.315 ENSMUST00000182594.1
Ank2
ankyrin 2, brain
chr4_+_42091207 2.270 ENSMUST00000178882.1
Gm3893
predicted gene 3893
chr10_-_123196916 2.242 ENSMUST00000020334.7
Usp15
ubiquitin specific peptidase 15
chr11_-_50931612 2.237 ENSMUST00000109124.3
Zfp354b
zinc finger protein 354B
chr11_+_53567361 2.232 ENSMUST00000057330.8
ENSMUST00000120613.2
ENSMUST00000173744.1
ENSMUST00000118353.2
Kif3a



kinesin family member 3A



chr1_-_153900198 2.227 ENSMUST00000123490.1
5830403L16Rik
RIKEN cDNA 5830403L16 gene
chr9_-_86880414 2.203 ENSMUST00000074501.5
ENSMUST00000098495.3
ENSMUST00000074468.6
ENSMUST00000036347.6
Snap91



synaptosomal-associated protein 91



chr2_-_7395879 2.193 ENSMUST00000182404.1
Celf2
CUGBP, Elav-like family member 2
chr6_-_121081589 2.172 ENSMUST00000077159.5
Mical3
microtubule associated monooxygenase, calponin and LIM domain containing 3
chr9_+_32116040 2.094 ENSMUST00000174641.1
Arhgap32
Rho GTPase activating protein 32
chr9_-_106656081 2.093 ENSMUST00000023959.7
Grm2
glutamate receptor, metabotropic 2
chr5_-_107972864 2.082 ENSMUST00000153172.1
Fam69a
family with sequence similarity 69, member A
chr13_+_24845122 2.070 ENSMUST00000006893.8
D130043K22Rik
RIKEN cDNA D130043K22 gene
chr17_+_35236556 1.979 ENSMUST00000068261.8
Atp6v1g2
ATPase, H+ transporting, lysosomal V1 subunit G2
chr9_-_121495678 1.978 ENSMUST00000035120.4
Cck
cholecystokinin
chr16_-_43979050 1.922 ENSMUST00000165648.1
ENSMUST00000036321.7
Zdhhc23

zinc finger, DHHC domain containing 23

chr13_+_46669517 1.920 ENSMUST00000099547.3
C78339
expressed sequence C78339
chr9_-_114933929 1.918 ENSMUST00000146623.1
Gpd1l
glycerol-3-phosphate dehydrogenase 1-like
chr2_-_7395968 1.915 ENSMUST00000002176.6
Celf2
CUGBP, Elav-like family member 2
chr3_-_107518001 1.885 ENSMUST00000169449.1
ENSMUST00000029499.8
Slc6a17

solute carrier family 6 (neurotransmitter transporter), member 17

chr3_-_152982240 1.884 ENSMUST00000044278.5
St6galnac5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr10_-_75797728 1.792 ENSMUST00000139724.1
Gstt1
glutathione S-transferase, theta 1
chr8_+_125730005 1.787 ENSMUST00000143504.1
Ntpcr
nucleoside-triphosphatase, cancer-related
chr11_+_78324200 1.771 ENSMUST00000102478.3
Aldoc
aldolase C, fructose-bisphosphate
chr4_-_119218165 1.762 ENSMUST00000030394.2
4930538K18Rik
RIKEN cDNA 4930538K18 gene
chr13_+_8885501 1.751 ENSMUST00000169314.2
Idi1
isopentenyl-diphosphate delta isomerase
chr11_-_29247208 1.725 ENSMUST00000020754.3
Ccdc104
coiled-coil domain containing 104
chr14_+_5517172 1.698 ENSMUST00000178220.1
Gm3488
predicted gene, 3488
chr14_+_5164535 1.698 ENSMUST00000179659.1
Gm3317
predicted gene 3317
chr4_+_42240639 1.692 ENSMUST00000117202.2
Gm10600
predicted gene 10600
chr14_+_3667518 1.625 ENSMUST00000112801.3
Gm3020
predicted gene 3020
chr1_+_25830657 1.620 ENSMUST00000064487.1
Gm9884
predicted gene 9884
chr3_-_146812951 1.558 ENSMUST00000102515.3
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr8_-_70234097 1.554 ENSMUST00000130319.1
Armc6
armadillo repeat containing 6
chr3_-_107969162 1.552 ENSMUST00000004136.8
ENSMUST00000106678.1
Gstm3

glutathione S-transferase, mu 3

chr4_+_41966058 1.541 ENSMUST00000108026.2
Gm20938
predicted gene, 20938
chr11_+_75348433 1.532 ENSMUST00000044530.2
Smyd4
SET and MYND domain containing 4
chr12_-_32953772 1.506 ENSMUST00000180391.1
ENSMUST00000181670.1
4933406C10Rik

RIKEN cDNA 4933406C10 gene

chr10_-_75797528 1.484 ENSMUST00000120177.1
Gstt1
glutathione S-transferase, theta 1
chr17_+_21423227 1.482 ENSMUST00000165230.1
ENSMUST00000007884.8
ENSMUST00000167749.1
Zfp54


zinc finger protein 54


chr18_+_63708689 1.477 ENSMUST00000072726.5
Wdr7
WD repeat domain 7
chr8_-_117673682 1.454 ENSMUST00000173522.1
ENSMUST00000174450.1
Sdr42e1

short chain dehydrogenase/reductase family 42E, member 1

chr18_+_42511496 1.451 ENSMUST00000025375.7
Tcerg1
transcription elongation regulator 1 (CA150)
chr16_+_13903152 1.449 ENSMUST00000128757.1
Mpv17l
Mpv17 transgene, kidney disease mutant-like
chr14_-_7473073 1.442 ENSMUST00000167833.2
Gm3752
predicted gene 3752
chr14_+_3348089 1.431 ENSMUST00000178722.1
Gm2956
predicted gene 2956
chr15_+_16778101 1.391 ENSMUST00000026432.6
Cdh9
cadherin 9
chr14_-_6874257 1.389 ENSMUST00000178298.1
ENSMUST00000179374.1
Gm3667
Gm3629
predicted gene 3667
predicted gene 3629
chr14_+_4126066 1.389 ENSMUST00000167397.2
Gm8108
predicted gene 8108
chr16_-_45158624 1.385 ENSMUST00000180636.1
Slc35a5
solute carrier family 35, member A5
chr5_-_123666682 1.359 ENSMUST00000149410.1
Clip1
CAP-GLY domain containing linker protein 1
chr4_-_129440800 1.350 ENSMUST00000053042.5
ENSMUST00000106046.1
Zbtb8b

zinc finger and BTB domain containing 8b

chr14_+_3428103 1.341 ENSMUST00000178060.1
Gm3005
predicted gene 3005
chr14_+_4430992 1.339 ENSMUST00000164603.1
ENSMUST00000166848.1
Gm3173

predicted gene 3173

chr14_+_4198185 1.321 ENSMUST00000180184.1
Gm2974
predicted gene 2974
chr14_+_4871156 1.318 ENSMUST00000166410.2
Gm3264
predicted gene 3264
chr2_-_7396192 1.312 ENSMUST00000137733.2
Celf2
CUGBP, Elav-like family member 2
chr10_+_97482350 1.309 ENSMUST00000163448.2
Dcn
decorin
chr1_-_52817643 1.290 ENSMUST00000027271.2
Inpp1
inositol polyphosphate-1-phosphatase
chr4_+_42318334 1.287 ENSMUST00000178192.1
Gm21598
predicted gene, 21598
chr14_+_4741737 1.258 ENSMUST00000178748.1
Gm3252
predicted gene 3252
chr6_+_126939957 1.256 ENSMUST00000032497.3
D6Wsu163e
DNA segment, Chr 6, Wayne State University 163, expressed
chr14_+_4514758 1.252 ENSMUST00000112776.2
Gm3173
predicted gene 3173
chr9_-_107541816 1.250 ENSMUST00000041459.3
Cyb561d2
cytochrome b-561 domain containing 2
chr14_-_6411578 1.249 ENSMUST00000179312.1
Gm3591
predicted gene 3591
chr16_-_45158566 1.249 ENSMUST00000181177.1
Slc35a5
solute carrier family 35, member A5
chr3_-_53863764 1.238 ENSMUST00000122330.1
ENSMUST00000146598.1
Ufm1

ubiquitin-fold modifier 1

chr10_-_77418230 1.236 ENSMUST00000020496.7
ENSMUST00000098374.2
ENSMUST00000105406.1
Adarb1


adenosine deaminase, RNA-specific, B1


chr2_-_128943985 1.234 ENSMUST00000028866.8
Zc3h8
zinc finger CCCH type containing 8
chr18_+_62548911 1.234 ENSMUST00000055725.4
ENSMUST00000162365.1
Spink10

serine peptidase inhibitor, Kazal type 10

chr14_+_3825596 1.225 ENSMUST00000178256.1
Gm3002
predicted gene 3002
chr7_-_127273919 1.217 ENSMUST00000082428.3
Sephs2
selenophosphate synthetase 2
chr12_+_64917901 1.214 ENSMUST00000058135.4
Gm527
predicted gene 527
chr1_-_37541003 1.211 ENSMUST00000151952.1
Mgat4a
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chr14_-_6266620 1.204 ENSMUST00000096172.5
Gm3411
predicted gene 3411
chr14_-_19569553 1.204 ENSMUST00000112595.2
Gm2237
predicted gene 2237
chr5_+_123076275 1.198 ENSMUST00000067505.8
ENSMUST00000111619.3
ENSMUST00000160344.1
Tmem120b


transmembrane protein 120B


chr1_-_6215292 1.196 ENSMUST00000097832.1
4732440D04Rik
RIKEN cDNA 4732440D04 gene
chr16_-_45158453 1.175 ENSMUST00000181750.1
Slc35a5
solute carrier family 35, member A5
chr9_+_107542209 1.173 ENSMUST00000010201.3
Nprl2
nitrogen permease regulator-like 2
chr8_-_115707778 1.117 ENSMUST00000109104.1
Maf
avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog
chr16_-_65562686 1.114 ENSMUST00000004965.6
Chmp2b
charged multivesicular body protein 2B
chr14_+_4665094 1.082 ENSMUST00000169675.2
Gm3239
predicted gene 3239
chrX_+_112600526 1.079 ENSMUST00000113409.1
Zfp711
zinc finger protein 711
chr5_-_23783700 1.057 ENSMUST00000119946.1
Pus7
pseudouridylate synthase 7 homolog (S. cerevisiae)
chr2_+_91096744 1.047 ENSMUST00000132741.2
Spi1
spleen focus forming virus (SFFV) proviral integration oncogene
chr2_+_32599698 1.021 ENSMUST00000131229.1
ENSMUST00000140983.1
ENSMUST00000095045.2
St6galnac6


ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6


chr4_+_106911517 1.020 ENSMUST00000072753.6
ENSMUST00000097934.3
Ssbp3

single-stranded DNA binding protein 3

chr10_+_122678764 1.016 ENSMUST00000161487.1
ENSMUST00000067918.5
Ppm1h

protein phosphatase 1H (PP2C domain containing)

chr2_-_33131645 1.004 ENSMUST00000133135.1
Garnl3
GTPase activating RANGAP domain-like 3
chr13_+_114818232 0.980 ENSMUST00000166104.2
ENSMUST00000166176.2
ENSMUST00000184335.1
ENSMUST00000184245.1
ENSMUST00000015680.4
ENSMUST00000184214.1
ENSMUST00000165022.2
ENSMUST00000164737.1
ENSMUST00000184781.1
ENSMUST00000183407.1
ENSMUST00000184672.1
Mocs2










molybdenum cofactor synthesis 2










chr4_+_127021311 0.961 ENSMUST00000030623.7
Sfpq
splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
chr7_+_46847128 0.955 ENSMUST00000005051.4
Ldha
lactate dehydrogenase A
chr14_-_5863663 0.949 ENSMUST00000178594.1
Gm8237
predicted gene 8237
chr7_+_120917744 0.935 ENSMUST00000033173.7
ENSMUST00000106483.2
Polr3e

polymerase (RNA) III (DNA directed) polypeptide E

chr16_+_91391721 0.934 ENSMUST00000160764.1
Gm21970
predicted gene 21970
chr13_+_108046411 0.928 ENSMUST00000095458.4
Smim15
small integral membrane protein 15
chr18_+_80255227 0.927 ENSMUST00000123750.1
Pqlc1
PQ loop repeat containing 1
chr14_-_6741430 0.922 ENSMUST00000100904.4
Gm3636
predicted gene 3636
chr2_+_91650169 0.914 ENSMUST00000090614.4
Arhgap1
Rho GTPase activating protein 1
chr11_+_70647258 0.914 ENSMUST00000037534.7
Rnf167
ring finger protein 167
chr1_-_33669745 0.905 ENSMUST00000027312.9
Prim2
DNA primase, p58 subunit
chr7_-_13009795 0.905 ENSMUST00000051390.7
ENSMUST00000172240.1
Zbtb45

zinc finger and BTB domain containing 45

chr7_+_110772604 0.892 ENSMUST00000005829.6
Ampd3
adenosine monophosphate deaminase 3
chr7_+_24507057 0.890 ENSMUST00000071361.6
Zfp428
zinc finger protein 428
chr16_-_91728975 0.889 ENSMUST00000073466.6
Cryzl1
crystallin, zeta (quinone reductase)-like 1
chr17_-_32350569 0.880 ENSMUST00000050214.7
Akap8l
A kinase (PRKA) anchor protein 8-like
chr3_+_146852359 0.876 ENSMUST00000038090.5
ENSMUST00000170055.1
Ttll7

tubulin tyrosine ligase-like family, member 7

chr3_-_110143937 0.858 ENSMUST00000051253.3
Ntng1
netrin G1
chr2_+_84826997 0.857 ENSMUST00000028470.3
Timm10
translocase of inner mitochondrial membrane 10
chr8_+_105276438 0.842 ENSMUST00000014920.6
Nol3
nucleolar protein 3 (apoptosis repressor with CARD domain)
chr8_+_70234187 0.834 ENSMUST00000164403.1
ENSMUST00000093458.4
Sugp2

SURP and G patch domain containing 2

chr9_+_123150941 0.833 ENSMUST00000026890.4
Clec3b
C-type lectin domain family 3, member b
chr8_+_71371283 0.828 ENSMUST00000110051.1
ENSMUST00000002469.8
ENSMUST00000110052.1
Ocel1


occludin/ELL domain containing 1


chr19_+_11965817 0.821 ENSMUST00000025590.9
Osbp
oxysterol binding protein
chr8_+_109868586 0.820 ENSMUST00000179721.1
ENSMUST00000034175.4
Phlpp2

PH domain and leucine rich repeat protein phosphatase 2

chr5_+_117357274 0.813 ENSMUST00000031309.9
Wsb2
WD repeat and SOCS box-containing 2
chr5_-_100373484 0.813 ENSMUST00000182433.1
Sec31a
Sec31 homolog A (S. cerevisiae)
chr3_-_96293953 0.804 ENSMUST00000029748.3
Fcgr1
Fc receptor, IgG, high affinity I
chr3_-_89160155 0.803 ENSMUST00000029686.3
Hcn3
hyperpolarization-activated, cyclic nucleotide-gated K+ 3
chr2_+_29124106 0.790 ENSMUST00000129544.1
Setx
senataxin
chr2_-_33718789 0.781 ENSMUST00000130532.1
9430024E24Rik
RIKEN cDNA 9430024E24 gene
chr8_-_111522073 0.780 ENSMUST00000034437.6
ENSMUST00000038193.7
Wdr59

WD repeat domain 59

chr4_+_118620799 0.775 ENSMUST00000030501.8
Ebna1bp2
EBNA1 binding protein 2
chr1_+_153899937 0.767 ENSMUST00000086199.5
Glul
glutamate-ammonia ligase (glutamine synthetase)
chr8_+_88697022 0.757 ENSMUST00000043526.8
Cyld
cylindromatosis (turban tumor syndrome)
chr13_+_23934434 0.751 ENSMUST00000072391.1
Hist1h2aa
histone cluster 1, H2aa
chr11_-_120617887 0.748 ENSMUST00000106188.3
ENSMUST00000026129.9
Pcyt2

phosphate cytidylyltransferase 2, ethanolamine

chr8_-_36732897 0.738 ENSMUST00000098826.3
Dlc1
deleted in liver cancer 1
chr17_+_24886643 0.735 ENSMUST00000117890.1
ENSMUST00000168265.1
ENSMUST00000120943.1
ENSMUST00000068508.6
ENSMUST00000119829.1
Spsb3




splA/ryanodine receptor domain and SOCS box containing 3




chr8_+_56294552 0.734 ENSMUST00000034026.8
Hpgd
hydroxyprostaglandin dehydrogenase 15 (NAD)
chr10_-_40246991 0.729 ENSMUST00000183114.1
ENSMUST00000045114.6
ENSMUST00000181995.1
ENSMUST00000183052.1
ENSMUST00000183309.1
Rpf2




ribosome production factor 2 homolog (S. cerevisiae)




chr8_-_71725696 0.728 ENSMUST00000153800.1
ENSMUST00000146100.1
Fcho1

FCH domain only 1

chr15_+_7129557 0.721 ENSMUST00000067190.5
ENSMUST00000164529.1
Lifr

leukemia inhibitory factor receptor

chr2_+_180598219 0.712 ENSMUST00000103059.1
Col9a3
collagen, type IX, alpha 3
chr10_-_29535857 0.700 ENSMUST00000092623.3
Rspo3
R-spondin 3 homolog (Xenopus laevis)
chr7_-_19310035 0.681 ENSMUST00000003640.2
Fosb
FBJ osteosarcoma oncogene B
chr5_+_105732063 0.677 ENSMUST00000154807.1
Lrrc8d
leucine rich repeat containing 8D
chr13_+_63815240 0.669 ENSMUST00000021926.5
ENSMUST00000095724.3
ENSMUST00000143449.1
ENSMUST00000067821.5
Ercc6l2



excision repair cross-complementing rodent repair deficiency, complementation group 6 like 2



chr11_+_53433299 0.661 ENSMUST00000018382.6
Gdf9
growth differentiation factor 9
chr10_+_81183000 0.649 ENSMUST00000178422.1
Dapk3
death-associated protein kinase 3
chr10_-_41303171 0.635 ENSMUST00000043814.3
Fig4
FIG4 homolog (S. cerevisiae)
chr15_-_78174090 0.626 ENSMUST00000016781.6
Ift27
intraflagellar transport 27
chrX_-_95956890 0.625 ENSMUST00000079987.6
ENSMUST00000113864.2
Las1l

LAS1-like (S. cerevisiae)

chr6_-_148212374 0.624 ENSMUST00000136008.1
ENSMUST00000032447.4
Ergic2

ERGIC and golgi 2

chr5_+_150673739 0.624 ENSMUST00000016569.4
ENSMUST00000038900.8
Pds5b

PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)

chr4_-_46196298 0.620 ENSMUST00000142380.1
ENSMUST00000058232.4
ENSMUST00000030013.5
Xpa


xeroderma pigmentosum, complementation group A


chr2_+_30266513 0.610 ENSMUST00000091132.6
Phyhd1
phytanoyl-CoA dioxygenase domain containing 1
chr11_-_83578496 0.608 ENSMUST00000019266.5
Ccl9
chemokine (C-C motif) ligand 9
chr7_+_67222544 0.606 ENSMUST00000058771.5
ENSMUST00000179106.1
Lysmd4

LysM, putative peptidoglycan-binding, domain containing 4

chr8_+_25601591 0.604 ENSMUST00000155861.1
Whsc1l1
Wolf-Hirschhorn syndrome candidate 1-like 1 (human)
chr6_+_106769120 0.596 ENSMUST00000113247.1
ENSMUST00000113249.1
ENSMUST00000057578.9
ENSMUST00000113248.1
Trnt1



tRNA nucleotidyl transferase, CCA-adding, 1



chr4_+_106911470 0.596 ENSMUST00000030367.8
ENSMUST00000149926.1
Ssbp3

single-stranded DNA binding protein 3

chr7_-_43533171 0.592 ENSMUST00000004728.5
ENSMUST00000039861.5
Cd33

CD33 antigen

chr2_+_91650116 0.588 ENSMUST00000111331.2
Arhgap1
Rho GTPase activating protein 1
chr2_+_120977017 0.585 ENSMUST00000067582.7
Tmem62
transmembrane protein 62
chr5_-_123572976 0.579 ENSMUST00000031388.8
Vps33a
vacuolar protein sorting 33A (yeast)
chrX_-_57392962 0.551 ENSMUST00000114730.1
Rbmx
RNA binding motif protein, X chromosome

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.3 GO:0099548 trans-synaptic signaling by nitric oxide(GO:0099548)
1.6 7.8 GO:1903587 negative regulation of peptidyl-serine dephosphorylation(GO:1902309) regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
1.5 4.4 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
1.4 4.3 GO:0044413 regulation of lung blood pressure(GO:0014916) evasion or tolerance of host defenses by virus(GO:0019049) positive regulation of transforming growth factor beta3 production(GO:0032916) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
1.1 3.3 GO:0042196 dichloromethane metabolic process(GO:0018900) chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197)
1.1 4.2 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.9 14.2 GO:0032098 regulation of appetite(GO:0032098)
0.9 3.7 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.7 2.2 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.7 2.6 GO:0032095 regulation of response to food(GO:0032095)
0.6 4.0 GO:0046549 retinal cone cell development(GO:0046549)
0.5 1.6 GO:2000744 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.5 3.0 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.5 2.8 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.5 2.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.5 3.2 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.4 2.2 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.4 3.4 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.4 0.8 GO:0014735 regulation of muscle atrophy(GO:0014735)
0.4 1.2 GO:0061744 motor behavior(GO:0061744)
0.4 1.9 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.4 4.0 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.3 2.4 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.3 4.5 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.3 1.4 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.3 1.0 GO:0031038 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
0.3 2.2 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.3 2.2 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.3 1.2 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.3 3.3 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.3 1.2 GO:0001887 selenium compound metabolic process(GO:0001887) selenocysteine metabolic process(GO:0016259)
0.3 1.5 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.3 1.8 GO:0046490 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.3 0.8 GO:0001803 antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.3 23.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.3 0.8 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.3 2.3 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.3 0.8 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.2 1.4 GO:0010730 negative regulation of hydrogen peroxide metabolic process(GO:0010727) negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.2 0.7 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.2 1.0 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.2 0.8 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.2 0.6 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.2 0.6 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.2 1.0 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.2 2.9 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.2 1.0 GO:0019659 fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.2 1.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 1.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.2 1.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.2 1.2 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.2 0.5 GO:0035963 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.2 0.9 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.2 6.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.2 0.2 GO:0039519 modulation by virus of host autophagy(GO:0039519)
0.2 0.8 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.2 0.5 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.1 0.4 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 2.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 1.6 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 0.4 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1 0.4 GO:0051105 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.1 0.4 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.1 1.0 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.1 0.9 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.1 0.9 GO:0030397 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.1 3.8 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 0.6 GO:0042701 progesterone secretion(GO:0042701)
0.1 0.4 GO:1902220 positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902220)
0.1 2.6 GO:0007020 microtubule nucleation(GO:0007020)
0.1 1.9 GO:0018345 protein palmitoylation(GO:0018345)
0.1 1.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.9 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 1.1 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.1 0.4 GO:0048296 negative regulation of isotype switching(GO:0045829) isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296)
0.1 0.4 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 2.6 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.1 0.4 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 0.3 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 0.7 GO:0007567 parturition(GO:0007567) ductus arteriosus closure(GO:0097070)
0.1 1.0 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.4 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.1 0.5 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.1 0.4 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.6 GO:0031642 negative regulation of myelination(GO:0031642)
0.1 0.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 2.1 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)
0.1 0.8 GO:0044144 regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144)
0.1 0.4 GO:0034214 protein hexamerization(GO:0034214)
0.1 0.2 GO:0090168 Golgi reassembly(GO:0090168)
0.1 0.4 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.1 0.8 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.7 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 2.1 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.1 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.6 GO:0048070 regulation of developmental pigmentation(GO:0048070)
0.1 0.6 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478)
0.1 0.3 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.3 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.3 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.4 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 2.2 GO:0030042 actin filament depolymerization(GO:0030042)
0.0 0.3 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 1.1 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.5 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.3 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.4 GO:0097066 response to thyroid hormone(GO:0097066)
0.0 0.2 GO:0010793 regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197)
0.0 0.3 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.6 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 2.0 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.5 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 1.8 GO:0046847 filopodium assembly(GO:0046847)
0.0 1.6 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.2 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 0.6 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 3.6 GO:0008643 carbohydrate transport(GO:0008643)
0.0 0.8 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.5 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.6 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.2 GO:0098707 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.1 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:0006533 aspartate catabolic process(GO:0006533) D-amino acid metabolic process(GO:0046416)
0.0 0.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.4 GO:0002250 adaptive immune response(GO:0002250)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 2.3 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.4 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.0 0.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.7 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.1 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.0 0.6 GO:0090102 cochlea development(GO:0090102)
0.0 2.1 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 1.2 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 1.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.3 GO:0098534 centriole replication(GO:0007099) centriole assembly(GO:0098534)
0.0 0.7 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.1 GO:0070627 ferrous iron import(GO:0070627)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.0 GO:0044316 cone cell pedicle(GO:0044316)
0.9 4.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.9 4.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.7 2.2 GO:0016939 kinesin II complex(GO:0016939)
0.7 2.2 GO:0098835 presynaptic endosome(GO:0098830) presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.3 2.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.3 4.0 GO:0097542 ciliary tip(GO:0097542)
0.3 1.5 GO:0097443 sorting endosome(GO:0097443)
0.3 2.6 GO:0005883 neurofilament(GO:0005883)
0.3 4.0 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.3 3.3 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.3 1.4 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.2 4.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 1.2 GO:1990130 Iml1 complex(GO:1990130)
0.2 3.6 GO:0005614 interstitial matrix(GO:0005614)
0.2 0.5 GO:0098888 extrinsic component of presynaptic membrane(GO:0098888)
0.2 23.9 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.2 0.6 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.2 3.4 GO:0044292 dendrite terminus(GO:0044292)
0.2 1.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.2 0.7 GO:0005594 collagen type IX trimer(GO:0005594)
0.2 0.9 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.2 0.8 GO:0001652 granular component(GO:0001652)
0.1 0.4 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 1.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.4 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 2.0 GO:0043203 axon hillock(GO:0043203)
0.1 0.8 GO:0061700 Seh1-associated complex(GO:0035859) GATOR2 complex(GO:0061700)
0.1 1.0 GO:0042382 paraspeckles(GO:0042382)
0.1 1.1 GO:0000815 ESCRT III complex(GO:0000815)
0.1 2.0 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.1 3.7 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 14.0 GO:0043204 perikaryon(GO:0043204)
0.1 2.4 GO:0000242 pericentriolar material(GO:0000242)
0.1 2.3 GO:0031430 M band(GO:0031430)
0.1 0.3 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 0.6 GO:0033263 CORVET complex(GO:0033263)
0.1 0.8 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 1.3 GO:0098644 complex of collagen trimers(GO:0098644)
0.1 1.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.3 GO:0034448 EGO complex(GO:0034448)
0.1 1.0 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.6 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.9 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.8 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.3 GO:0098536 deuterosome(GO:0098536)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.6 GO:0097228 sperm principal piece(GO:0097228)
0.0 1.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 2.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 1.5 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.1 GO:0038201 TOR complex(GO:0038201)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.8 GO:0034399 nuclear periphery(GO:0034399)
0.0 0.5 GO:0051233 spindle midzone(GO:0051233)
0.0 0.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 3.2 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 1.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 2.6 GO:0001650 fibrillar center(GO:0001650)
0.0 0.7 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 3.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 4.3 GO:0000139 Golgi membrane(GO:0000139)
0.0 4.8 GO:0016607 nuclear speck(GO:0016607)
0.0 0.4 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.2 GO:0042641 actomyosin(GO:0042641)
0.0 0.6 GO:0005811 lipid particle(GO:0005811)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0008502 melatonin receptor activity(GO:0008502)
1.1 3.3 GO:0019120 hydrolase activity, acting on acid halide bonds(GO:0016824) hydrolase activity, acting on acid halide bonds, in C-halide compounds(GO:0019120) alkylhalidase activity(GO:0047651)
0.9 3.8 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.9 2.6 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.9 4.4 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.9 4.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.7 8.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.7 13.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.4 3.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.4 2.1 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.4 2.9 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.4 2.3 GO:0097016 L27 domain binding(GO:0097016)
0.4 2.6 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.3 2.0 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.3 1.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.3 1.8 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.3 1.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.3 4.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.3 0.8 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.3 0.8 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)
0.2 1.5 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.2 1.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 0.7 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924)
0.2 1.0 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.2 0.9 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.2 0.8 GO:0035877 death effector domain binding(GO:0035877)
0.2 0.8 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.2 2.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 5.3 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2 3.4 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.2 0.5 GO:0004127 cytidylate kinase activity(GO:0004127)
0.2 1.0 GO:0051525 NFAT protein binding(GO:0051525)
0.2 2.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 3.8 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.2 0.8 GO:0019770 IgG receptor activity(GO:0019770)
0.2 2.9 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 1.8 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.2 1.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 0.9 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.2 1.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.2 4.5 GO:0030552 cAMP binding(GO:0030552)
0.1 2.8 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 0.7 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.1 0.4 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.4 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 0.9 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.6 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 1.9 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.1 0.3 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 0.4 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 0.4 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.7 GO:0017166 vinculin binding(GO:0017166)
0.1 2.2 GO:0071949 FAD binding(GO:0071949)
0.1 1.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 5.4 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 0.8 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.4 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 2.0 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 7.3 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 1.0 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.2 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.1 1.0 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 4.5 GO:0030507 spectrin binding(GO:0030507)
0.1 0.3 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.1 1.0 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 1.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 2.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.7 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.1 0.5 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.7 GO:0008097 5S rRNA binding(GO:0008097)
0.1 2.6 GO:0005179 hormone activity(GO:0005179)
0.1 1.5 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.9 GO:0005521 lamin binding(GO:0005521)
0.1 21.5 GO:0003779 actin binding(GO:0003779)
0.0 0.4 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.8 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 5.2 GO:0008201 heparin binding(GO:0008201)
0.0 3.4 GO:0005125 cytokine activity(GO:0005125)
0.0 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.0 1.3 GO:0005539 glycosaminoglycan binding(GO:0005539)
0.0 0.4 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.0 0.3 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.6 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.5 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 4.0 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.2 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 0.1 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 0.4 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.9 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.4 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.4 GO:0043394 glycoprotein binding(GO:0001948) proteoglycan binding(GO:0043394)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.5 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.5 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.0 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.2 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.3 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 0.5 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.1 3.0 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.1 2.1 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.1 1.8 PID_IL3_PATHWAY IL3-mediated signaling events
0.0 2.7 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 3.0 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 1.3 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.1 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.5 SIG_CHEMOTAXIS Genes related to chemotaxis
0.0 1.0 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 0.7 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.9 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.3 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.4 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.8 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.0 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.9 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 1.1 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 0.3 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.3 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.5 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 23.8 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.3 10.9 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.2 19.9 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.2 2.4 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.2 4.3 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.2 6.0 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.2 2.1 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 4.4 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.1 2.6 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 2.8 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.3 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 1.0 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.9 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.1 0.4 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.1 1.8 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.2 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.1 0.7 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.1 0.4 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 0.9 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.1 1.9 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.7 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.8 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.6 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 1.4 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.9 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.0 1.1 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 3.4 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.0 0.3 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 1.4 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.2 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.6 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 2.0 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.5 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 0.8 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.2 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.0 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.1 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.0 0.7 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 0.2 REACTOME_FORMATION_OF_TRANSCRIPTION_COUPLED_NER_TC_NER_REPAIR_COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex