Motif ID: Myog_Tcf12
Z-value: 0.813
Transcription factors associated with Myog_Tcf12:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Myog | ENSMUSG00000026459.4 | Myog |
| Tcf12 | ENSMUSG00000032228.10 | Tcf12 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Tcf12 | mm10_v2_chr9_-_72111651_72111712 | -0.71 | 3.1e-07 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.7 | 11.2 | GO:0006601 | creatine biosynthetic process(GO:0006601) |
| 2.9 | 8.7 | GO:0071374 | cellular response to parathyroid hormone stimulus(GO:0071374) |
| 2.8 | 16.7 | GO:0046880 | regulation of follicle-stimulating hormone secretion(GO:0046880) follicle-stimulating hormone secretion(GO:0046884) |
| 2.2 | 10.8 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
| 1.6 | 4.7 | GO:0032430 | inhibitory G-protein coupled receptor phosphorylation(GO:0002030) positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466) |
| 1.4 | 5.8 | GO:0014012 | peripheral nervous system axon regeneration(GO:0014012) |
| 1.4 | 4.2 | GO:0072378 | blood coagulation, fibrin clot formation(GO:0072378) |
| 1.4 | 7.0 | GO:0032423 | regulation of mismatch repair(GO:0032423) |
| 1.4 | 7.0 | GO:0035405 | histone-threonine phosphorylation(GO:0035405) |
| 1.3 | 5.2 | GO:0021586 | pons maturation(GO:0021586) |
| 1.2 | 10.9 | GO:0036371 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
| 1.1 | 3.4 | GO:0038095 | positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095) |
| 1.0 | 2.0 | GO:0045110 | intermediate filament bundle assembly(GO:0045110) |
| 1.0 | 1.0 | GO:0021966 | corticospinal neuron axon guidance(GO:0021966) |
| 1.0 | 3.0 | GO:0061153 | trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) |
| 0.9 | 2.8 | GO:2000501 | natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501) |
| 0.9 | 1.8 | GO:2000402 | negative regulation of lymphocyte migration(GO:2000402) |
| 0.9 | 2.6 | GO:0060596 | mammary placode formation(GO:0060596) |
| 0.9 | 2.6 | GO:0050925 | negative regulation of negative chemotaxis(GO:0050925) |
| 0.9 | 3.5 | GO:2000832 | androgen secretion(GO:0035935) testosterone secretion(GO:0035936) positive regulation of apoptotic DNA fragmentation(GO:1902512) negative regulation of steroid hormone secretion(GO:2000832) regulation of androgen secretion(GO:2000834) regulation of testosterone secretion(GO:2000843) |
| 0.9 | 0.9 | GO:0007567 | parturition(GO:0007567) |
| 0.8 | 4.1 | GO:1903587 | regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) |
| 0.7 | 5.1 | GO:0014819 | regulation of skeletal muscle contraction(GO:0014819) |
| 0.7 | 2.1 | GO:1903244 | positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) regulation of connective tissue replacement(GO:1905203) |
| 0.7 | 2.7 | GO:0099566 | regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566) |
| 0.7 | 1.3 | GO:0060025 | regulation of synaptic activity(GO:0060025) |
| 0.6 | 3.2 | GO:0060591 | chondroblast differentiation(GO:0060591) |
| 0.6 | 2.4 | GO:0045113 | regulation of integrin biosynthetic process(GO:0045113) |
| 0.6 | 2.9 | GO:1903609 | negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609) |
| 0.5 | 0.5 | GO:0010499 | proteasomal ubiquitin-independent protein catabolic process(GO:0010499) |
| 0.5 | 1.6 | GO:0051542 | elastin biosynthetic process(GO:0051542) |
| 0.5 | 1.6 | GO:0018199 | peptidyl-glutamine modification(GO:0018199) |
| 0.5 | 2.5 | GO:0002121 | inter-male aggressive behavior(GO:0002121) |
| 0.5 | 1.5 | GO:1904049 | negative regulation of spontaneous neurotransmitter secretion(GO:1904049) |
| 0.5 | 1.4 | GO:1903279 | regulation of calcium:sodium antiporter activity(GO:1903279) |
| 0.5 | 1.4 | GO:0001830 | trophectodermal cell fate commitment(GO:0001830) |
| 0.5 | 2.7 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
| 0.4 | 1.3 | GO:1903538 | meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538) |
| 0.4 | 2.2 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 0.4 | 1.3 | GO:0048687 | positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) |
| 0.4 | 1.8 | GO:0048069 | eye pigmentation(GO:0048069) |
| 0.4 | 1.3 | GO:0044339 | canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339) |
| 0.4 | 1.3 | GO:1990523 | bone regeneration(GO:1990523) |
| 0.4 | 1.3 | GO:0003345 | proepicardium cell migration involved in pericardium morphogenesis(GO:0003345) |
| 0.4 | 1.2 | GO:0061075 | cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871) |
| 0.4 | 0.4 | GO:0002159 | desmosome assembly(GO:0002159) |
| 0.4 | 1.5 | GO:0090238 | positive regulation of arachidonic acid secretion(GO:0090238) |
| 0.4 | 1.1 | GO:0046168 | glycerol-3-phosphate catabolic process(GO:0046168) |
| 0.4 | 1.5 | GO:0001550 | ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) |
| 0.4 | 1.5 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
| 0.4 | 1.8 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
| 0.4 | 0.7 | GO:1904717 | regulation of AMPA glutamate receptor clustering(GO:1904717) |
| 0.4 | 2.1 | GO:0098964 | dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964) |
| 0.3 | 1.0 | GO:1900060 | negative regulation of ceramide biosynthetic process(GO:1900060) |
| 0.3 | 1.4 | GO:1900740 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
| 0.3 | 1.0 | GO:0032224 | positive regulation of synaptic transmission, cholinergic(GO:0032224) |
| 0.3 | 0.7 | GO:2000987 | positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987) |
| 0.3 | 3.2 | GO:0016127 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
| 0.3 | 2.5 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.3 | 1.3 | GO:1990034 | calcium ion export from cell(GO:1990034) |
| 0.3 | 4.7 | GO:1902260 | negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817) |
| 0.3 | 1.5 | GO:0060075 | regulation of resting membrane potential(GO:0060075) |
| 0.3 | 1.8 | GO:0051665 | membrane raft localization(GO:0051665) |
| 0.3 | 1.2 | GO:0061743 | motor learning(GO:0061743) |
| 0.3 | 1.8 | GO:0097491 | trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287) |
| 0.3 | 2.3 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.3 | 0.6 | GO:0032914 | positive regulation of transforming growth factor beta1 production(GO:0032914) |
| 0.3 | 2.0 | GO:0009449 | gamma-aminobutyric acid biosynthetic process(GO:0009449) |
| 0.3 | 1.7 | GO:0002317 | plasma cell differentiation(GO:0002317) positive regulation of viral entry into host cell(GO:0046598) |
| 0.3 | 24.8 | GO:0030032 | lamellipodium assembly(GO:0030032) |
| 0.3 | 1.9 | GO:0010459 | negative regulation of heart rate(GO:0010459) |
| 0.3 | 1.4 | GO:0060762 | regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) |
| 0.3 | 1.7 | GO:0003096 | renal sodium ion transport(GO:0003096) |
| 0.3 | 1.6 | GO:0099550 | trans-synaptic signalling, modulating synaptic transmission(GO:0099550) |
| 0.3 | 0.8 | GO:0015938 | coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) |
| 0.3 | 0.8 | GO:0003104 | positive regulation of glomerular filtration(GO:0003104) negative regulation of phosphatidylinositol biosynthetic process(GO:0010512) phenotypic switching(GO:0036166) metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262) |
| 0.3 | 0.5 | GO:0003274 | tolerance induction to self antigen(GO:0002513) endocardial cushion fusion(GO:0003274) |
| 0.3 | 4.2 | GO:0001573 | ganglioside metabolic process(GO:0001573) |
| 0.3 | 1.3 | GO:0061304 | retinal blood vessel morphogenesis(GO:0061304) |
| 0.3 | 4.0 | GO:0007216 | G-protein coupled glutamate receptor signaling pathway(GO:0007216) |
| 0.3 | 0.8 | GO:0098528 | skeletal muscle fiber differentiation(GO:0098528) |
| 0.2 | 0.7 | GO:0098928 | presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526) |
| 0.2 | 1.2 | GO:0099628 | receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628) |
| 0.2 | 3.4 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
| 0.2 | 1.5 | GO:0060718 | chorionic trophoblast cell differentiation(GO:0060718) |
| 0.2 | 0.9 | GO:0032227 | negative regulation of synaptic transmission, dopaminergic(GO:0032227) |
| 0.2 | 1.4 | GO:1901844 | regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) |
| 0.2 | 1.6 | GO:0014832 | urinary bladder smooth muscle contraction(GO:0014832) |
| 0.2 | 0.7 | GO:0015882 | L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904) |
| 0.2 | 7.9 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
| 0.2 | 0.9 | GO:1904451 | regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453) |
| 0.2 | 0.9 | GO:0090168 | Golgi reassembly(GO:0090168) |
| 0.2 | 0.7 | GO:0051305 | chromosome movement towards spindle pole(GO:0051305) |
| 0.2 | 3.0 | GO:0045161 | neuronal ion channel clustering(GO:0045161) |
| 0.2 | 1.1 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.2 | 2.1 | GO:0097119 | postsynaptic density protein 95 clustering(GO:0097119) |
| 0.2 | 0.2 | GO:1904020 | regulation of G-protein coupled receptor internalization(GO:1904020) |
| 0.2 | 1.7 | GO:0036376 | sodium ion export from cell(GO:0036376) |
| 0.2 | 0.8 | GO:0035435 | phosphate ion transmembrane transport(GO:0035435) |
| 0.2 | 3.8 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
| 0.2 | 0.2 | GO:0021612 | facial nerve structural organization(GO:0021612) |
| 0.2 | 0.6 | GO:0015772 | disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772) |
| 0.2 | 3.7 | GO:0010763 | positive regulation of fibroblast migration(GO:0010763) |
| 0.2 | 1.1 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
| 0.2 | 1.3 | GO:0060267 | positive regulation of respiratory burst(GO:0060267) |
| 0.2 | 1.5 | GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
| 0.2 | 0.6 | GO:0035470 | positive regulation of vascular wound healing(GO:0035470) |
| 0.2 | 2.2 | GO:0061436 | establishment of skin barrier(GO:0061436) |
| 0.2 | 3.7 | GO:0008210 | estrogen metabolic process(GO:0008210) |
| 0.2 | 3.1 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504) |
| 0.2 | 1.4 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 0.2 | 2.8 | GO:0070296 | sarcoplasmic reticulum calcium ion transport(GO:0070296) |
| 0.2 | 6.7 | GO:0014741 | negative regulation of cardiac muscle hypertrophy(GO:0010614) negative regulation of muscle hypertrophy(GO:0014741) |
| 0.2 | 1.4 | GO:0051014 | actin filament severing(GO:0051014) |
| 0.2 | 0.7 | GO:0006706 | steroid catabolic process(GO:0006706) |
| 0.2 | 0.9 | GO:0015817 | histidine transport(GO:0015817) cellular response to potassium ion starvation(GO:0051365) |
| 0.2 | 0.7 | GO:0008295 | spermidine biosynthetic process(GO:0008295) |
| 0.2 | 1.0 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
| 0.2 | 0.5 | GO:0021785 | branchiomotor neuron axon guidance(GO:0021785) |
| 0.2 | 3.1 | GO:0002091 | negative regulation of receptor internalization(GO:0002091) |
| 0.2 | 0.6 | GO:0072061 | inner medullary collecting duct development(GO:0072061) |
| 0.2 | 4.4 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.2 | 0.6 | GO:0045346 | regulation of MHC class II biosynthetic process(GO:0045346) negative regulation of MHC class II biosynthetic process(GO:0045347) |
| 0.2 | 0.5 | GO:0021933 | radial glia guided migration of cerebellar granule cell(GO:0021933) |
| 0.2 | 2.5 | GO:2001014 | regulation of skeletal muscle cell differentiation(GO:2001014) |
| 0.2 | 0.6 | GO:0033580 | protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125) |
| 0.2 | 1.5 | GO:0046958 | nonassociative learning(GO:0046958) habituation(GO:0046959) |
| 0.2 | 0.9 | GO:0003374 | dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374) synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) |
| 0.2 | 1.4 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
| 0.2 | 1.4 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.1 | 1.0 | GO:0015862 | uridine transport(GO:0015862) |
| 0.1 | 7.3 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.1 | 0.7 | GO:0070305 | response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321) |
| 0.1 | 0.7 | GO:0099612 | protein localization to axon(GO:0099612) |
| 0.1 | 0.6 | GO:0007171 | activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) |
| 0.1 | 0.9 | GO:0003418 | growth plate cartilage chondrocyte differentiation(GO:0003418) |
| 0.1 | 0.9 | GO:0002036 | regulation of L-glutamate transport(GO:0002036) |
| 0.1 | 0.6 | GO:0046391 | 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391) |
| 0.1 | 1.2 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
| 0.1 | 5.9 | GO:0006779 | porphyrin-containing compound biosynthetic process(GO:0006779) |
| 0.1 | 1.0 | GO:0061002 | negative regulation of dendritic spine morphogenesis(GO:0061002) |
| 0.1 | 0.4 | GO:1902310 | positive regulation of peptidyl-serine dephosphorylation(GO:1902310) |
| 0.1 | 2.2 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.1 | 0.8 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 0.1 | 1.0 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 0.1 | 0.1 | GO:0021604 | cranial nerve structural organization(GO:0021604) |
| 0.1 | 0.1 | GO:0032714 | negative regulation of interleukin-13 production(GO:0032696) negative regulation of interleukin-5 production(GO:0032714) negative regulation of interleukin-10 secretion(GO:2001180) |
| 0.1 | 0.6 | GO:1902237 | positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237) |
| 0.1 | 0.6 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
| 0.1 | 1.0 | GO:0006883 | cellular sodium ion homeostasis(GO:0006883) |
| 0.1 | 0.6 | GO:0007182 | common-partner SMAD protein phosphorylation(GO:0007182) |
| 0.1 | 0.9 | GO:0002710 | negative regulation of T cell mediated immunity(GO:0002710) |
| 0.1 | 1.3 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.1 | 0.4 | GO:0046543 | development of secondary female sexual characteristics(GO:0046543) |
| 0.1 | 0.4 | GO:0019085 | early viral transcription(GO:0019085) |
| 0.1 | 0.5 | GO:1901475 | pyruvate transmembrane transport(GO:1901475) |
| 0.1 | 0.6 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 0.1 | 0.9 | GO:0060120 | auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120) |
| 0.1 | 0.5 | GO:0006848 | pyruvate transport(GO:0006848) |
| 0.1 | 0.6 | GO:0070278 | extracellular matrix constituent secretion(GO:0070278) |
| 0.1 | 1.2 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
| 0.1 | 1.0 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.1 | 0.7 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
| 0.1 | 0.7 | GO:1990481 | mRNA pseudouridine synthesis(GO:1990481) |
| 0.1 | 0.4 | GO:0016340 | calcium-dependent cell-matrix adhesion(GO:0016340) |
| 0.1 | 0.5 | GO:0032796 | uropod organization(GO:0032796) |
| 0.1 | 1.1 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.1 | 1.3 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
| 0.1 | 0.8 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
| 0.1 | 0.5 | GO:0033632 | regulation of cell-cell adhesion mediated by integrin(GO:0033632) |
| 0.1 | 1.0 | GO:0043589 | skin morphogenesis(GO:0043589) |
| 0.1 | 0.5 | GO:1902047 | polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) |
| 0.1 | 2.3 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.1 | 0.6 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.1 | 1.3 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
| 0.1 | 0.9 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
| 0.1 | 0.3 | GO:0009182 | purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066) GDP metabolic process(GO:0046710) |
| 0.1 | 0.7 | GO:0016264 | gap junction assembly(GO:0016264) |
| 0.1 | 2.0 | GO:0045475 | locomotor rhythm(GO:0045475) |
| 0.1 | 0.9 | GO:0002087 | regulation of respiratory gaseous exchange by neurological system process(GO:0002087) |
| 0.1 | 0.5 | GO:0048539 | bone marrow development(GO:0048539) |
| 0.1 | 0.5 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 0.1 | 0.4 | GO:0010800 | positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
| 0.1 | 0.5 | GO:0010668 | ectodermal cell differentiation(GO:0010668) |
| 0.1 | 1.3 | GO:0014067 | negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067) |
| 0.1 | 0.4 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
| 0.1 | 1.1 | GO:0045217 | cell-cell junction maintenance(GO:0045217) |
| 0.1 | 0.5 | GO:0098967 | exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967) |
| 0.1 | 1.7 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
| 0.1 | 0.4 | GO:1904017 | response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017) |
| 0.1 | 0.4 | GO:0090527 | actin filament reorganization(GO:0090527) |
| 0.1 | 0.3 | GO:0060923 | cardiac muscle cell fate commitment(GO:0060923) |
| 0.1 | 2.2 | GO:0031571 | mitotic G1 DNA damage checkpoint(GO:0031571) |
| 0.1 | 0.2 | GO:1904978 | postsynaptic neurotransmitter receptor internalization(GO:0098884) regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980) |
| 0.1 | 1.0 | GO:1903818 | positive regulation of voltage-gated potassium channel activity(GO:1903818) |
| 0.1 | 0.4 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
| 0.1 | 0.5 | GO:0010572 | positive regulation of platelet activation(GO:0010572) |
| 0.1 | 0.7 | GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) |
| 0.1 | 0.6 | GO:0010804 | negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804) |
| 0.1 | 0.4 | GO:0046826 | negative regulation of protein export from nucleus(GO:0046826) |
| 0.1 | 0.5 | GO:0061622 | glycolytic process through glucose-1-phosphate(GO:0061622) |
| 0.1 | 0.7 | GO:0034390 | smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391) |
| 0.1 | 0.4 | GO:0035720 | intraciliary anterograde transport(GO:0035720) |
| 0.1 | 0.5 | GO:0031547 | brain-derived neurotrophic factor receptor signaling pathway(GO:0031547) |
| 0.1 | 0.3 | GO:1904152 | negative regulation of protein exit from endoplasmic reticulum(GO:0070862) regulation of retrograde protein transport, ER to cytosol(GO:1904152) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153) |
| 0.1 | 0.2 | GO:0045662 | negative regulation of myoblast differentiation(GO:0045662) |
| 0.1 | 0.4 | GO:0070166 | enamel mineralization(GO:0070166) |
| 0.1 | 1.3 | GO:0071158 | positive regulation of cell cycle arrest(GO:0071158) |
| 0.1 | 0.4 | GO:0046855 | phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) |
| 0.1 | 0.6 | GO:0031848 | protection from non-homologous end joining at telomere(GO:0031848) |
| 0.1 | 0.4 | GO:0033140 | negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140) |
| 0.1 | 0.6 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
| 0.1 | 0.3 | GO:0006121 | mitochondrial electron transport, succinate to ubiquinone(GO:0006121) |
| 0.1 | 0.3 | GO:1900016 | negative regulation of cytokine production involved in inflammatory response(GO:1900016) |
| 0.1 | 0.2 | GO:0035509 | negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) |
| 0.1 | 0.4 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
| 0.1 | 0.9 | GO:0021527 | spinal cord association neuron differentiation(GO:0021527) |
| 0.1 | 0.2 | GO:0035523 | protein K29-linked deubiquitination(GO:0035523) protein K6-linked deubiquitination(GO:0044313) |
| 0.1 | 0.8 | GO:0060052 | neurofilament cytoskeleton organization(GO:0060052) |
| 0.1 | 0.2 | GO:0006285 | base-excision repair, AP site formation(GO:0006285) |
| 0.1 | 0.3 | GO:0050684 | regulation of mRNA processing(GO:0050684) |
| 0.1 | 0.1 | GO:2000286 | receptor internalization involved in canonical Wnt signaling pathway(GO:2000286) |
| 0.1 | 0.8 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
| 0.1 | 0.2 | GO:0019805 | quinolinate biosynthetic process(GO:0019805) |
| 0.1 | 0.9 | GO:2000649 | regulation of sodium ion transmembrane transporter activity(GO:2000649) |
| 0.1 | 0.5 | GO:1900454 | positive regulation of long term synaptic depression(GO:1900454) |
| 0.1 | 0.5 | GO:0019262 | N-acetylneuraminate catabolic process(GO:0019262) |
| 0.1 | 0.4 | GO:2001268 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268) |
| 0.1 | 0.2 | GO:0040010 | positive regulation of growth rate(GO:0040010) |
| 0.1 | 0.7 | GO:0031639 | plasminogen activation(GO:0031639) |
| 0.1 | 0.2 | GO:0090646 | mitochondrial tRNA processing(GO:0090646) |
| 0.1 | 2.0 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
| 0.1 | 0.1 | GO:0072239 | metanephric glomerulus vasculature development(GO:0072239) |
| 0.1 | 0.2 | GO:0009186 | deoxyribonucleoside diphosphate metabolic process(GO:0009186) |
| 0.1 | 0.5 | GO:1903025 | regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025) |
| 0.1 | 1.0 | GO:0001964 | startle response(GO:0001964) |
| 0.1 | 0.6 | GO:0050910 | detection of mechanical stimulus involved in sensory perception of sound(GO:0050910) |
| 0.1 | 0.4 | GO:0071260 | cellular response to mechanical stimulus(GO:0071260) |
| 0.1 | 1.5 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.1 | 0.5 | GO:0021678 | third ventricle development(GO:0021678) |
| 0.1 | 0.1 | GO:0002191 | cap-dependent translational initiation(GO:0002191) |
| 0.1 | 0.5 | GO:0006013 | mannose metabolic process(GO:0006013) |
| 0.1 | 0.5 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
| 0.1 | 0.2 | GO:2000393 | negative regulation of lamellipodium organization(GO:1902744) negative regulation of lamellipodium morphogenesis(GO:2000393) |
| 0.1 | 0.5 | GO:0034551 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033) |
| 0.1 | 2.7 | GO:0046579 | positive regulation of Ras protein signal transduction(GO:0046579) |
| 0.1 | 0.1 | GO:2000277 | positive regulation of oxidative phosphorylation uncoupler activity(GO:2000277) |
| 0.1 | 0.7 | GO:0033599 | regulation of mammary gland epithelial cell proliferation(GO:0033599) |
| 0.1 | 0.5 | GO:0035024 | negative regulation of Rho protein signal transduction(GO:0035024) |
| 0.1 | 1.8 | GO:0046627 | negative regulation of insulin receptor signaling pathway(GO:0046627) |
| 0.1 | 0.3 | GO:0048703 | embryonic viscerocranium morphogenesis(GO:0048703) |
| 0.1 | 0.8 | GO:0071624 | positive regulation of granulocyte chemotaxis(GO:0071624) positive regulation of neutrophil chemotaxis(GO:0090023) |
| 0.0 | 0.6 | GO:1901223 | negative regulation of NIK/NF-kappaB signaling(GO:1901223) |
| 0.0 | 0.4 | GO:0035608 | protein deglutamylation(GO:0035608) |
| 0.0 | 0.3 | GO:0032439 | endosome localization(GO:0032439) |
| 0.0 | 0.3 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
| 0.0 | 0.3 | GO:0090070 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
| 0.0 | 0.3 | GO:1900017 | positive regulation of cytokine production involved in inflammatory response(GO:1900017) |
| 0.0 | 0.1 | GO:0010814 | substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959) |
| 0.0 | 0.9 | GO:0008340 | determination of adult lifespan(GO:0008340) |
| 0.0 | 0.5 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
| 0.0 | 0.3 | GO:0001927 | exocyst assembly(GO:0001927) |
| 0.0 | 0.4 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.0 | 1.5 | GO:0045668 | negative regulation of osteoblast differentiation(GO:0045668) |
| 0.0 | 0.1 | GO:0009414 | response to water deprivation(GO:0009414) |
| 0.0 | 0.8 | GO:0043496 | regulation of protein homodimerization activity(GO:0043496) |
| 0.0 | 2.0 | GO:0071346 | cellular response to interferon-gamma(GO:0071346) |
| 0.0 | 1.0 | GO:0006182 | cGMP biosynthetic process(GO:0006182) |
| 0.0 | 0.1 | GO:0018103 | protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406) |
| 0.0 | 0.2 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
| 0.0 | 0.4 | GO:0060394 | negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394) |
| 0.0 | 0.0 | GO:0097360 | chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382) |
| 0.0 | 0.6 | GO:0036295 | cellular response to increased oxygen levels(GO:0036295) |
| 0.0 | 0.2 | GO:0006741 | NADP biosynthetic process(GO:0006741) |
| 0.0 | 0.6 | GO:0050909 | sensory perception of taste(GO:0050909) |
| 0.0 | 0.3 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
| 0.0 | 1.5 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.0 | 0.3 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
| 0.0 | 4.2 | GO:0016579 | protein deubiquitination(GO:0016579) |
| 0.0 | 0.5 | GO:0034244 | negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) |
| 0.0 | 0.1 | GO:0001955 | blood vessel maturation(GO:0001955) |
| 0.0 | 0.4 | GO:1904816 | positive regulation of protein localization to chromosome, telomeric region(GO:1904816) |
| 0.0 | 0.2 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
| 0.0 | 0.5 | GO:0001916 | positive regulation of T cell mediated cytotoxicity(GO:0001916) |
| 0.0 | 1.4 | GO:0043407 | negative regulation of MAP kinase activity(GO:0043407) |
| 0.0 | 0.5 | GO:0043248 | proteasome assembly(GO:0043248) |
| 0.0 | 0.3 | GO:0044344 | cellular response to fibroblast growth factor stimulus(GO:0044344) |
| 0.0 | 0.1 | GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
| 0.0 | 0.0 | GO:0060423 | foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) positive regulation of branching involved in lung morphogenesis(GO:0061047) |
| 0.0 | 1.9 | GO:0021766 | hippocampus development(GO:0021766) |
| 0.0 | 0.5 | GO:0006415 | translational termination(GO:0006415) |
| 0.0 | 0.2 | GO:0070314 | G1 to G0 transition(GO:0070314) |
| 0.0 | 0.7 | GO:0031116 | positive regulation of microtubule polymerization(GO:0031116) |
| 0.0 | 0.3 | GO:0050965 | detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965) |
| 0.0 | 0.5 | GO:0060628 | regulation of ER to Golgi vesicle-mediated transport(GO:0060628) |
| 0.0 | 0.6 | GO:0034063 | stress granule assembly(GO:0034063) |
| 0.0 | 0.4 | GO:0036297 | interstrand cross-link repair(GO:0036297) |
| 0.0 | 2.6 | GO:0048709 | oligodendrocyte differentiation(GO:0048709) |
| 0.0 | 0.7 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
| 0.0 | 0.5 | GO:0043113 | receptor clustering(GO:0043113) |
| 0.0 | 0.1 | GO:0001193 | maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193) |
| 0.0 | 0.4 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
| 0.0 | 0.1 | GO:0009227 | UDP-N-acetylglucosamine catabolic process(GO:0006049) nucleotide-sugar catabolic process(GO:0009227) |
| 0.0 | 0.3 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
| 0.0 | 0.2 | GO:0014002 | astrocyte development(GO:0014002) |
| 0.0 | 0.2 | GO:0007342 | fusion of sperm to egg plasma membrane(GO:0007342) |
| 0.0 | 0.1 | GO:0030950 | establishment or maintenance of actin cytoskeleton polarity(GO:0030950) |
| 0.0 | 0.7 | GO:0007200 | phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200) |
| 0.0 | 0.3 | GO:0060670 | branching involved in labyrinthine layer morphogenesis(GO:0060670) |
| 0.0 | 0.8 | GO:1904893 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
| 0.0 | 0.1 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
| 0.0 | 0.1 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 0.0 | 0.2 | GO:0031268 | pseudopodium organization(GO:0031268) |
| 0.0 | 0.2 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
| 0.0 | 1.6 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
| 0.0 | 0.6 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
| 0.0 | 0.1 | GO:0060050 | positive regulation of protein glycosylation(GO:0060050) |
| 0.0 | 0.0 | GO:0014826 | vein smooth muscle contraction(GO:0014826) |
| 0.0 | 0.3 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.0 | 0.2 | GO:2000653 | regulation of genetic imprinting(GO:2000653) |
| 0.0 | 0.1 | GO:0060314 | regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314) |
| 0.0 | 0.1 | GO:0035963 | response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963) |
| 0.0 | 0.3 | GO:0001954 | positive regulation of cell-matrix adhesion(GO:0001954) |
| 0.0 | 0.1 | GO:1901216 | positive regulation of neuron death(GO:1901216) |
| 0.0 | 0.1 | GO:0030968 | endoplasmic reticulum unfolded protein response(GO:0030968) cellular response to unfolded protein(GO:0034620) cellular response to topologically incorrect protein(GO:0035967) |
| 0.0 | 0.2 | GO:0006903 | vesicle targeting(GO:0006903) |
| 0.0 | 0.8 | GO:0030042 | actin filament depolymerization(GO:0030042) |
| 0.0 | 0.1 | GO:0086011 | membrane repolarization during action potential(GO:0086011) |
| 0.0 | 0.1 | GO:0032380 | regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383) |
| 0.0 | 1.2 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
| 0.0 | 0.1 | GO:0006102 | isocitrate metabolic process(GO:0006102) |
| 0.0 | 0.7 | GO:0008333 | endosome to lysosome transport(GO:0008333) |
| 0.0 | 0.2 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.0 | 0.4 | GO:2000785 | regulation of autophagosome assembly(GO:2000785) |
| 0.0 | 1.8 | GO:0010977 | negative regulation of neuron projection development(GO:0010977) |
| 0.0 | 1.6 | GO:0071804 | cellular potassium ion transport(GO:0071804) |
| 0.0 | 0.2 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
| 0.0 | 0.4 | GO:0048678 | response to axon injury(GO:0048678) |
| 0.0 | 1.0 | GO:0016525 | negative regulation of angiogenesis(GO:0016525) |
| 0.0 | 0.5 | GO:0043388 | positive regulation of DNA binding(GO:0043388) |
| 0.0 | 0.1 | GO:0033483 | gas homeostasis(GO:0033483) |
| 0.0 | 0.1 | GO:0048170 | positive regulation of long-term neuronal synaptic plasticity(GO:0048170) |
| 0.0 | 0.3 | GO:0021680 | cerebellar Purkinje cell layer development(GO:0021680) |
| 0.0 | 0.1 | GO:0032485 | regulation of Ral protein signal transduction(GO:0032485) |
| 0.0 | 0.3 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.0 | 0.3 | GO:0000731 | DNA synthesis involved in DNA repair(GO:0000731) |
| 0.0 | 0.4 | GO:0045806 | negative regulation of endocytosis(GO:0045806) |
| 0.0 | 0.2 | GO:1900153 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153) |
| 0.0 | 0.3 | GO:0071218 | cellular response to misfolded protein(GO:0071218) |
| 0.0 | 0.3 | GO:0006826 | iron ion transport(GO:0006826) |
| 0.0 | 0.3 | GO:0015991 | ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662) |
| 0.0 | 0.1 | GO:0016446 | somatic hypermutation of immunoglobulin genes(GO:0016446) |
| 0.0 | 0.1 | GO:0034766 | negative regulation of ion transmembrane transport(GO:0034766) |
| 0.0 | 0.1 | GO:1901798 | positive regulation of signal transduction by p53 class mediator(GO:1901798) |
| 0.0 | 4.0 | GO:0007283 | spermatogenesis(GO:0007283) |
| 0.0 | 0.3 | GO:1903078 | positive regulation of protein localization to plasma membrane(GO:1903078) |
| 0.0 | 0.1 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
| 0.0 | 0.3 | GO:0051453 | regulation of intracellular pH(GO:0051453) |
| 0.0 | 0.1 | GO:2001243 | negative regulation of intrinsic apoptotic signaling pathway(GO:2001243) |
| 0.0 | 0.0 | GO:0006436 | tryptophanyl-tRNA aminoacylation(GO:0006436) |
| 0.0 | 0.5 | GO:0015992 | proton transport(GO:0015992) |
| 0.0 | 0.9 | GO:0051017 | actin filament bundle assembly(GO:0051017) actin filament bundle organization(GO:0061572) |
| 0.0 | 0.3 | GO:0000470 | maturation of LSU-rRNA(GO:0000470) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.6 | 16.7 | GO:0043512 | inhibin A complex(GO:0043512) |
| 1.0 | 3.9 | GO:0044307 | dendritic branch(GO:0044307) |
| 0.9 | 3.5 | GO:0042567 | insulin-like growth factor ternary complex(GO:0042567) |
| 0.9 | 2.6 | GO:0005940 | septin ring(GO:0005940) |
| 0.6 | 17.2 | GO:0031430 | M band(GO:0031430) |
| 0.6 | 2.9 | GO:0005587 | collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651) |
| 0.5 | 3.0 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.5 | 7.2 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.4 | 3.1 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.4 | 1.3 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
| 0.4 | 5.9 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.4 | 1.2 | GO:0099573 | glutamatergic postsynaptic density(GO:0099573) |
| 0.4 | 1.5 | GO:1902937 | inward rectifier potassium channel complex(GO:1902937) |
| 0.3 | 1.0 | GO:0005584 | collagen type I trimer(GO:0005584) |
| 0.3 | 1.3 | GO:0008091 | spectrin(GO:0008091) |
| 0.3 | 1.6 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.3 | 0.3 | GO:0032279 | asymmetric synapse(GO:0032279) |
| 0.3 | 1.5 | GO:1990761 | growth cone lamellipodium(GO:1990761) |
| 0.3 | 1.5 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
| 0.3 | 2.6 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.3 | 1.4 | GO:1990796 | photoreceptor cell terminal bouton(GO:1990796) |
| 0.3 | 2.8 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.3 | 0.3 | GO:0016342 | catenin complex(GO:0016342) |
| 0.3 | 1.0 | GO:0035339 | SPOTS complex(GO:0035339) |
| 0.3 | 0.8 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 0.2 | 0.7 | GO:0098855 | HCN channel complex(GO:0098855) |
| 0.2 | 0.7 | GO:1990769 | proximal neuron projection(GO:1990769) |
| 0.2 | 3.7 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
| 0.2 | 4.5 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.2 | 25.7 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.2 | 0.2 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.2 | 2.0 | GO:0005883 | neurofilament(GO:0005883) |
| 0.2 | 1.1 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 0.2 | 2.9 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.2 | 0.9 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
| 0.2 | 7.8 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
| 0.2 | 3.0 | GO:0031045 | dense core granule(GO:0031045) |
| 0.2 | 1.0 | GO:0030314 | junctional membrane complex(GO:0030314) |
| 0.2 | 0.7 | GO:0099569 | presynaptic cytoskeleton(GO:0099569) |
| 0.2 | 2.7 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.2 | 13.3 | GO:0034705 | voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705) |
| 0.2 | 0.7 | GO:0032280 | symmetric synapse(GO:0032280) |
| 0.2 | 1.6 | GO:0032426 | stereocilium tip(GO:0032426) |
| 0.2 | 1.2 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
| 0.2 | 0.6 | GO:0002141 | stereocilia ankle link(GO:0002141) |
| 0.1 | 3.1 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
| 0.1 | 3.1 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.1 | 10.6 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.1 | 4.7 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.1 | 1.3 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.1 | 0.4 | GO:0044614 | nuclear pore cytoplasmic filaments(GO:0044614) |
| 0.1 | 2.0 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
| 0.1 | 0.5 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
| 0.1 | 2.5 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.1 | 1.0 | GO:0033268 | node of Ranvier(GO:0033268) |
| 0.1 | 0.6 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.1 | 0.8 | GO:0070695 | FHF complex(GO:0070695) |
| 0.1 | 1.9 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.1 | 2.0 | GO:0030673 | axolemma(GO:0030673) |
| 0.1 | 1.4 | GO:0031672 | A band(GO:0031672) |
| 0.1 | 0.7 | GO:0097449 | astrocyte projection(GO:0097449) |
| 0.1 | 0.7 | GO:0014704 | intercalated disc(GO:0014704) |
| 0.1 | 1.6 | GO:0016471 | vacuolar proton-transporting V-type ATPase complex(GO:0016471) |
| 0.1 | 3.8 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.1 | 3.6 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.1 | 1.5 | GO:0031527 | filopodium membrane(GO:0031527) |
| 0.1 | 0.3 | GO:0042720 | mitochondrial inner membrane peptidase complex(GO:0042720) |
| 0.1 | 0.4 | GO:0070820 | tertiary granule(GO:0070820) |
| 0.1 | 5.9 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.1 | 26.7 | GO:0097060 | synaptic membrane(GO:0097060) |
| 0.1 | 4.1 | GO:0045335 | phagocytic vesicle(GO:0045335) |
| 0.1 | 0.2 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
| 0.1 | 0.3 | GO:0070436 | Grb2-EGFR complex(GO:0070436) |
| 0.1 | 0.8 | GO:0034706 | voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706) |
| 0.1 | 1.4 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.1 | 1.9 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.1 | 1.3 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.1 | 0.8 | GO:0043679 | axon terminus(GO:0043679) |
| 0.1 | 1.6 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.1 | 0.8 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.1 | 0.2 | GO:0043540 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540) |
| 0.1 | 0.6 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
| 0.1 | 6.6 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.1 | 0.6 | GO:0098644 | complex of collagen trimers(GO:0098644) |
| 0.1 | 0.8 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.1 | 0.5 | GO:0002102 | podosome(GO:0002102) |
| 0.1 | 1.0 | GO:0030867 | rough endoplasmic reticulum membrane(GO:0030867) |
| 0.0 | 0.3 | GO:0045179 | apical cortex(GO:0045179) |
| 0.0 | 0.3 | GO:0005827 | polar microtubule(GO:0005827) |
| 0.0 | 2.4 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 0.7 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.0 | 1.4 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.0 | 0.3 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
| 0.0 | 1.9 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 0.9 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.0 | 0.9 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
| 0.0 | 1.0 | GO:0032420 | stereocilium(GO:0032420) |
| 0.0 | 0.3 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
| 0.0 | 0.7 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 0.6 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.0 | 0.2 | GO:0000836 | ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836) |
| 0.0 | 1.5 | GO:0005884 | actin filament(GO:0005884) |
| 0.0 | 0.7 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.0 | 0.1 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 0.0 | 0.1 | GO:0044302 | dentate gyrus mossy fiber(GO:0044302) |
| 0.0 | 0.2 | GO:0034709 | methylosome(GO:0034709) |
| 0.0 | 2.7 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 0.3 | GO:0005686 | U2 snRNP(GO:0005686) |
| 0.0 | 0.5 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
| 0.0 | 0.3 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.0 | 1.4 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 0.8 | GO:0045178 | basal part of cell(GO:0045178) |
| 0.0 | 0.6 | GO:0030139 | endocytic vesicle(GO:0030139) |
| 0.0 | 0.3 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.0 | 0.1 | GO:0070847 | core mediator complex(GO:0070847) |
| 0.0 | 0.2 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.0 | 0.5 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 0.1 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 0.0 | 2.3 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.0 | 0.5 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.0 | 0.9 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 0.6 | GO:0030686 | 90S preribosome(GO:0030686) |
| 0.0 | 0.5 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.0 | 0.1 | GO:0090543 | Flemming body(GO:0090543) |
| 0.0 | 1.8 | GO:0022626 | cytosolic ribosome(GO:0022626) |
| 0.0 | 0.1 | GO:0097361 | CIA complex(GO:0097361) |
| 0.0 | 0.4 | GO:0031305 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
| 0.0 | 0.0 | GO:0048179 | activin receptor complex(GO:0048179) |
| 0.0 | 0.9 | GO:0045121 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
| 0.0 | 0.2 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.0 | 0.1 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
| 0.0 | 0.2 | GO:0031597 | cytosolic proteasome complex(GO:0031597) |
| 0.0 | 0.3 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
| 0.0 | 0.0 | GO:0097637 | intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637) |
| 0.0 | 1.1 | GO:0043197 | dendritic spine(GO:0043197) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.3 | 7.0 | GO:0004698 | calcium-dependent protein kinase C activity(GO:0004698) |
| 1.8 | 11.0 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 1.4 | 7.0 | GO:0035184 | histone threonine kinase activity(GO:0035184) |
| 1.1 | 4.2 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 1.0 | 5.8 | GO:0045545 | syndecan binding(GO:0045545) |
| 0.9 | 6.3 | GO:0034711 | inhibin binding(GO:0034711) |
| 0.8 | 6.5 | GO:0099529 | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) |
| 0.8 | 4.8 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
| 0.8 | 1.5 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
| 0.7 | 3.5 | GO:0072542 | protein phosphatase activator activity(GO:0072542) |
| 0.7 | 2.7 | GO:0043125 | ErbB-3 class receptor binding(GO:0043125) |
| 0.7 | 4.6 | GO:0086008 | voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008) |
| 0.6 | 1.8 | GO:0046624 | sphingolipid transporter activity(GO:0046624) |
| 0.6 | 2.9 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
| 0.6 | 2.9 | GO:0070320 | inward rectifier potassium channel inhibitor activity(GO:0070320) |
| 0.5 | 8.3 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.5 | 2.6 | GO:0005030 | neurotrophin receptor activity(GO:0005030) |
| 0.5 | 3.0 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 0.5 | 3.5 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
| 0.5 | 10.7 | GO:0016769 | transferase activity, transferring nitrogenous groups(GO:0016769) |
| 0.5 | 1.8 | GO:0004952 | dopamine neurotransmitter receptor activity(GO:0004952) |
| 0.5 | 3.2 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.5 | 1.8 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 0.4 | 3.6 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.4 | 2.1 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) |
| 0.4 | 2.5 | GO:0045340 | mercury ion binding(GO:0045340) |
| 0.4 | 1.9 | GO:0005534 | galactose binding(GO:0005534) |
| 0.4 | 5.1 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.4 | 1.8 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.3 | 1.4 | GO:0047275 | glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275) |
| 0.3 | 1.0 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
| 0.3 | 1.3 | GO:0031800 | type 3 metabotropic glutamate receptor binding(GO:0031800) |
| 0.3 | 2.6 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.3 | 1.0 | GO:0022865 | transmembrane electron transfer carrier(GO:0022865) |
| 0.3 | 3.1 | GO:0008556 | sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556) |
| 0.3 | 0.9 | GO:0008527 | taste receptor activity(GO:0008527) |
| 0.3 | 6.4 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
| 0.3 | 4.7 | GO:0004033 | aldo-keto reductase (NADP) activity(GO:0004033) |
| 0.3 | 1.2 | GO:0016230 | sphingomyelin phosphodiesterase activator activity(GO:0016230) |
| 0.3 | 2.0 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
| 0.3 | 0.9 | GO:0015182 | L-asparagine transmembrane transporter activity(GO:0015182) |
| 0.3 | 2.9 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.3 | 1.3 | GO:2001070 | starch binding(GO:2001070) |
| 0.3 | 10.1 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.3 | 2.1 | GO:0036122 | BMP binding(GO:0036122) |
| 0.3 | 1.0 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
| 0.3 | 5.3 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.2 | 1.7 | GO:0001515 | opioid peptide activity(GO:0001515) |
| 0.2 | 10.0 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 0.2 | 3.7 | GO:0004890 | GABA-A receptor activity(GO:0004890) GABA receptor activity(GO:0016917) |
| 0.2 | 0.7 | GO:0070890 | L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890) |
| 0.2 | 4.8 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.2 | 1.1 | GO:0004367 | glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367) |
| 0.2 | 11.1 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
| 0.2 | 1.8 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 0.2 | 1.0 | GO:0019871 | sodium channel inhibitor activity(GO:0019871) |
| 0.2 | 0.8 | GO:0005315 | inorganic phosphate transmembrane transporter activity(GO:0005315) |
| 0.2 | 1.8 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.2 | 1.0 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 0.2 | 0.6 | GO:0008515 | sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157) |
| 0.2 | 0.6 | GO:0032052 | bile acid binding(GO:0032052) |
| 0.2 | 0.8 | GO:0070012 | oligopeptidase activity(GO:0070012) |
| 0.2 | 0.7 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
| 0.2 | 0.6 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
| 0.2 | 1.5 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.2 | 2.0 | GO:0005024 | transforming growth factor beta-activated receptor activity(GO:0005024) |
| 0.2 | 0.7 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 0.2 | 1.6 | GO:0016755 | transferase activity, transferring amino-acyl groups(GO:0016755) |
| 0.2 | 0.9 | GO:0004954 | icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955) |
| 0.2 | 1.9 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
| 0.2 | 2.0 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.2 | 3.5 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.2 | 1.0 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 0.2 | 1.3 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.2 | 1.0 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
| 0.2 | 0.8 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
| 0.2 | 2.1 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 0.2 | 2.4 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.2 | 1.9 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.2 | 0.6 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
| 0.2 | 1.4 | GO:0017081 | chloride channel regulator activity(GO:0017081) |
| 0.2 | 0.5 | GO:0045127 | N-acetylglucosamine kinase activity(GO:0045127) |
| 0.1 | 2.2 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.1 | 3.2 | GO:0042287 | MHC protein binding(GO:0042287) |
| 0.1 | 0.4 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 0.1 | 0.8 | GO:0005042 | netrin receptor activity(GO:0005042) |
| 0.1 | 0.4 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
| 0.1 | 0.9 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
| 0.1 | 0.9 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.1 | 1.6 | GO:0030955 | potassium ion binding(GO:0030955) |
| 0.1 | 3.0 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.1 | 1.0 | GO:0070097 | delta-catenin binding(GO:0070097) |
| 0.1 | 0.5 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
| 0.1 | 1.5 | GO:0016863 | intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863) |
| 0.1 | 0.5 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
| 0.1 | 1.0 | GO:0034046 | poly(G) binding(GO:0034046) |
| 0.1 | 0.9 | GO:0031749 | D2 dopamine receptor binding(GO:0031749) |
| 0.1 | 0.6 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.1 | 0.7 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.1 | 0.5 | GO:0042979 | ornithine decarboxylase regulator activity(GO:0042979) |
| 0.1 | 0.4 | GO:0034481 | N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537) chondroitin sulfotransferase activity(GO:0034481) |
| 0.1 | 0.6 | GO:0047276 | N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276) |
| 0.1 | 2.1 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 0.1 | 0.3 | GO:0044715 | 8-oxo-dGDP phosphatase activity(GO:0044715) |
| 0.1 | 0.3 | GO:0019002 | GMP binding(GO:0019002) |
| 0.1 | 0.4 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.1 | 1.2 | GO:0005522 | profilin binding(GO:0005522) |
| 0.1 | 1.0 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.1 | 0.5 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 0.1 | 0.5 | GO:0050544 | arachidonic acid binding(GO:0050544) |
| 0.1 | 0.9 | GO:0005161 | platelet-derived growth factor receptor binding(GO:0005161) |
| 0.1 | 0.2 | GO:0015562 | efflux transmembrane transporter activity(GO:0015562) |
| 0.1 | 0.5 | GO:0033691 | sialic acid binding(GO:0033691) |
| 0.1 | 2.0 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.1 | 0.7 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 0.1 | 0.2 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
| 0.1 | 0.2 | GO:0070139 | ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139) |
| 0.1 | 0.1 | GO:0005131 | growth hormone receptor binding(GO:0005131) |
| 0.1 | 0.5 | GO:0048403 | brain-derived neurotrophic factor binding(GO:0048403) |
| 0.1 | 1.3 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.1 | 1.1 | GO:0048018 | receptor agonist activity(GO:0048018) |
| 0.1 | 0.2 | GO:0052743 | inositol tetrakisphosphate phosphatase activity(GO:0052743) |
| 0.1 | 7.9 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
| 0.1 | 0.8 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 0.1 | 3.8 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.1 | 1.3 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.1 | 0.4 | GO:0043237 | laminin-1 binding(GO:0043237) |
| 0.1 | 0.4 | GO:0033142 | progesterone receptor binding(GO:0033142) |
| 0.1 | 0.3 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.1 | 0.5 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 0.1 | 0.9 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
| 0.1 | 0.5 | GO:0003747 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
| 0.1 | 0.6 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
| 0.1 | 1.3 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.1 | 2.4 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
| 0.1 | 1.7 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.1 | 1.5 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.1 | 0.2 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
| 0.1 | 0.1 | GO:0034190 | apolipoprotein receptor binding(GO:0034190) |
| 0.1 | 3.2 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
| 0.1 | 0.2 | GO:0004127 | cytidylate kinase activity(GO:0004127) uridylate kinase activity(GO:0009041) |
| 0.1 | 0.3 | GO:0070330 | aromatase activity(GO:0070330) |
| 0.1 | 0.4 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.1 | 2.3 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.1 | 5.9 | GO:0036459 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
| 0.1 | 0.8 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |
| 0.1 | 1.5 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.1 | 0.2 | GO:0031826 | type 2A serotonin receptor binding(GO:0031826) |
| 0.1 | 1.6 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.1 | 0.9 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 0.1 | 0.5 | GO:0019534 | toxin transporter activity(GO:0019534) |
| 0.1 | 0.5 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.1 | 0.3 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
| 0.1 | 0.4 | GO:0016312 | inositol bisphosphate phosphatase activity(GO:0016312) |
| 0.1 | 1.5 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.1 | 0.5 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 0.1 | 2.8 | GO:0004879 | RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531) |
| 0.1 | 1.5 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.1 | 0.2 | GO:0000702 | oxidized base lesion DNA N-glycosylase activity(GO:0000702) |
| 0.1 | 1.3 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
| 0.1 | 1.0 | GO:0008009 | chemokine activity(GO:0008009) |
| 0.1 | 0.6 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.1 | 2.0 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.0 | 0.2 | GO:0043812 | phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) |
| 0.0 | 3.7 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 13.1 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.0 | 0.9 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.0 | 0.5 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.0 | 0.1 | GO:0004169 | dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169) |
| 0.0 | 2.1 | GO:0032947 | protein complex scaffold(GO:0032947) |
| 0.0 | 17.6 | GO:0003779 | actin binding(GO:0003779) |
| 0.0 | 1.2 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.0 | 0.1 | GO:0042954 | lipoprotein transporter activity(GO:0042954) |
| 0.0 | 0.7 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.0 | 0.0 | GO:0016361 | activin receptor activity, type I(GO:0016361) activin-activated receptor activity(GO:0017002) |
| 0.0 | 0.6 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.0 | 0.4 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.0 | 0.6 | GO:0042805 | actinin binding(GO:0042805) |
| 0.0 | 0.1 | GO:0051538 | 3 iron, 4 sulfur cluster binding(GO:0051538) |
| 0.0 | 0.6 | GO:0005537 | mannose binding(GO:0005537) |
| 0.0 | 4.7 | GO:0001191 | transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191) |
| 0.0 | 1.0 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 0.6 | GO:0030553 | cGMP binding(GO:0030553) |
| 0.0 | 0.2 | GO:0050692 | DBD domain binding(GO:0050692) |
| 0.0 | 2.1 | GO:0051117 | ATPase binding(GO:0051117) |
| 0.0 | 0.5 | GO:0004559 | alpha-mannosidase activity(GO:0004559) mannosidase activity(GO:0015923) |
| 0.0 | 0.5 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.0 | 1.1 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
| 0.0 | 0.6 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.0 | 0.2 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.0 | 1.1 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.0 | 0.7 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 0.0 | 3.9 | GO:0052689 | carboxylic ester hydrolase activity(GO:0052689) |
| 0.0 | 0.3 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.0 | 2.8 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.0 | 0.2 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.0 | 0.5 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.0 | 0.3 | GO:0015093 | ferrous iron transmembrane transporter activity(GO:0015093) |
| 0.0 | 0.4 | GO:0051018 | protein kinase A binding(GO:0051018) |
| 0.0 | 1.0 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 2.0 | GO:0005516 | calmodulin binding(GO:0005516) |
| 0.0 | 0.1 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 0.0 | 0.2 | GO:0003951 | NAD+ kinase activity(GO:0003951) |
| 0.0 | 0.4 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.0 | 1.8 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
| 0.0 | 0.3 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.0 | 0.2 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.0 | 0.3 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.0 | 0.2 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 0.0 | 0.2 | GO:0035251 | UDP-glucosyltransferase activity(GO:0035251) |
| 0.0 | 0.8 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.0 | 0.2 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
| 0.0 | 0.1 | GO:2001069 | glycogen binding(GO:2001069) |
| 0.0 | 0.3 | GO:0008484 | sulfuric ester hydrolase activity(GO:0008484) |
| 0.0 | 0.2 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.0 | 0.1 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
| 0.0 | 0.1 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
| 0.0 | 1.4 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.2 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 0.0 | 0.6 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
| 0.0 | 0.1 | GO:0004303 | estradiol 17-beta-dehydrogenase activity(GO:0004303) |
| 0.0 | 0.5 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.0 | 0.2 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.0 | 0.2 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.0 | 0.3 | GO:0017171 | serine-type peptidase activity(GO:0008236) serine hydrolase activity(GO:0017171) |
| 0.0 | 0.2 | GO:0032183 | SUMO binding(GO:0032183) |
| 0.0 | 1.2 | GO:0016798 | hydrolase activity, acting on glycosyl bonds(GO:0016798) |
| 0.0 | 0.2 | GO:0030552 | cAMP binding(GO:0030552) |
| 0.0 | 0.1 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.0 | 0.1 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
| 0.0 | 0.3 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
| 0.0 | 0.2 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 0.0 | 0.3 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 0.0 | GO:0004830 | tryptophan-tRNA ligase activity(GO:0004830) |
| 0.0 | 1.7 | GO:0008514 | organic anion transmembrane transporter activity(GO:0008514) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 15.2 | PID_IL8_CXCR1_PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.4 | 11.5 | PID_IL12_STAT4_PATHWAY | IL12 signaling mediated by STAT4 |
| 0.4 | 13.3 | PID_ALK1_PATHWAY | ALK1 signaling events |
| 0.4 | 10.0 | PID_INTEGRIN_A9B1_PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.3 | 5.1 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
| 0.3 | 4.3 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
| 0.3 | 11.8 | PID_RAS_PATHWAY | Regulation of Ras family activation |
| 0.3 | 3.5 | PID_INTEGRIN5_PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.2 | 8.2 | PID_MAPK_TRK_PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.2 | 3.1 | PID_LYMPH_ANGIOGENESIS_PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 0.2 | 3.4 | ST_GA12_PATHWAY | G alpha 12 Pathway |
| 0.1 | 3.9 | PID_P38_ALPHA_BETA_PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.1 | 4.5 | PID_SHP2_PATHWAY | SHP2 signaling |
| 0.1 | 3.0 | PID_TRKR_PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.1 | 0.8 | ST_GRANULE_CELL_SURVIVAL_PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.1 | 0.7 | ST_PAC1_RECEPTOR_PATHWAY | PAC1 Receptor Pathway |
| 0.1 | 0.6 | PID_VEGF_VEGFR_PATHWAY | VEGF and VEGFR signaling network |
| 0.1 | 2.4 | PID_PI3K_PLC_TRK_PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.1 | 1.8 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.1 | 1.8 | PID_REELIN_PATHWAY | Reelin signaling pathway |
| 0.1 | 3.1 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.1 | 0.1 | PID_S1P_S1P2_PATHWAY | S1P2 pathway |
| 0.1 | 1.8 | SIG_CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.1 | 0.4 | PID_ECADHERIN_KERATINOCYTE_PATHWAY | E-cadherin signaling in keratinocytes |
| 0.1 | 6.7 | PID_PDGFRB_PATHWAY | PDGFR-beta signaling pathway |
| 0.1 | 2.5 | PID_LYSOPHOSPHOLIPID_PATHWAY | LPA receptor mediated events |
| 0.1 | 0.5 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
| 0.1 | 1.3 | PID_ANGIOPOIETIN_RECEPTOR_PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.1 | 0.5 | PID_P38_GAMMA_DELTA_PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.1 | 1.1 | PID_TGFBR_PATHWAY | TGF-beta receptor signaling |
| 0.1 | 0.7 | PID_AP1_PATHWAY | AP-1 transcription factor network |
| 0.1 | 3.4 | PID_MYC_REPRESS_PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.1 | 0.7 | PID_AMB2_NEUTROPHILS_PATHWAY | amb2 Integrin signaling |
| 0.1 | 0.5 | PID_ATF2_PATHWAY | ATF-2 transcription factor network |
| 0.0 | 0.9 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
| 0.0 | 1.0 | PID_FRA_PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.0 | 1.0 | PID_INTEGRIN3_PATHWAY | Beta3 integrin cell surface interactions |
| 0.0 | 0.5 | PID_PTP1B_PATHWAY | Signaling events mediated by PTP1B |
| 0.0 | 0.5 | PID_TCPTP_PATHWAY | Signaling events mediated by TCPTP |
| 0.0 | 0.2 | PID_NEPHRIN_NEPH1_PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
| 0.0 | 0.3 | ST_T_CELL_SIGNAL_TRANSDUCTION | T Cell Signal Transduction |
| 0.0 | 0.4 | PID_ERB_GENOMIC_PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 0.2 | ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS | Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway. |
| 0.0 | 0.9 | PID_ERBB1_INTERNALIZATION_PATHWAY | Internalization of ErbB1 |
| 0.0 | 1.4 | PID_LKB1_PATHWAY | LKB1 signaling events |
| 0.0 | 0.3 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
| 0.0 | 1.7 | PID_P73PATHWAY | p73 transcription factor network |
| 0.0 | 1.9 | PID_CMYB_PATHWAY | C-MYB transcription factor network |
| 0.0 | 0.1 | PID_CXCR3_PATHWAY | CXCR3-mediated signaling events |
| 0.0 | 0.2 | PID_RANBP2_PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.0 | 3.9 | NABA_SECRETED_FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 0.6 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 0.3 | PID_PI3KCI_PATHWAY | Class I PI3K signaling events |
| 0.0 | 0.0 | PID_ER_NONGENOMIC_PATHWAY | Plasma membrane estrogen receptor signaling |
| 0.0 | 0.2 | PID_HIF1A_PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.0 | 0.2 | PID_ARF6_PATHWAY | Arf6 signaling events |
| 0.0 | 0.3 | PID_BMP_PATHWAY | BMP receptor signaling |
| 0.0 | 0.2 | PID_HDAC_CLASSIII_PATHWAY | Signaling events mediated by HDAC Class III |
| 0.0 | 0.3 | PID_RHOA_PATHWAY | RhoA signaling pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.2 | 16.7 | REACTOME_GLYCOPROTEIN_HORMONES | Genes involved in Glycoprotein hormones |
| 1.0 | 2.0 | REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES | Genes involved in Cross-presentation of soluble exogenous antigens (endosomes) |
| 0.9 | 25.3 | REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.7 | 4.2 | REACTOME_COMMON_PATHWAY | Genes involved in Common Pathway |
| 0.7 | 4.7 | REACTOME_ENDOGENOUS_STEROLS | Genes involved in Endogenous sterols |
| 0.6 | 17.6 | REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.6 | 14.3 | REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
| 0.4 | 4.8 | REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY | Genes involved in Adenylate cyclase activating pathway |
| 0.4 | 2.5 | REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 0.3 | 1.7 | REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
| 0.3 | 4.3 | REACTOME_GABA_A_RECEPTOR_ACTIVATION | Genes involved in GABA A receptor activation |
| 0.3 | 6.2 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
| 0.2 | 7.7 | REACTOME_ERK_MAPK_TARGETS | Genes involved in ERK/MAPK targets |
| 0.2 | 9.9 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.2 | 5.9 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.2 | 2.4 | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.2 | 2.8 | REACTOME_TIE2_SIGNALING | Genes involved in Tie2 Signaling |
| 0.2 | 5.3 | REACTOME_BASIGIN_INTERACTIONS | Genes involved in Basigin interactions |
| 0.2 | 1.8 | REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
| 0.2 | 1.8 | REACTOME_SHC_MEDIATED_SIGNALLING | Genes involved in SHC-mediated signalling |
| 0.2 | 12.5 | REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.2 | 5.3 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.2 | 2.0 | REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.2 | 2.4 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.1 | 4.7 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
| 0.1 | 2.5 | REACTOME_INSULIN_RECEPTOR_RECYCLING | Genes involved in Insulin receptor recycling |
| 0.1 | 2.6 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.1 | 4.2 | REACTOME_INWARDLY_RECTIFYING_K_CHANNELS | Genes involved in Inwardly rectifying K+ channels |
| 0.1 | 1.4 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.1 | 3.2 | REACTOME_SYNTHESIS_OF_PA | Genes involved in Synthesis of PA |
| 0.1 | 1.9 | REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.1 | 1.1 | REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.1 | 0.8 | REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.1 | 2.0 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.1 | 4.1 | REACTOME_L1CAM_INTERACTIONS | Genes involved in L1CAM interactions |
| 0.1 | 0.8 | REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.1 | 0.8 | REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
| 0.1 | 1.2 | REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.1 | 1.4 | REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.1 | 2.1 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.1 | 2.4 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.1 | 0.7 | REACTOME_SYNTHESIS_OF_PE | Genes involved in Synthesis of PE |
| 0.1 | 0.6 | REACTOME_KERATAN_SULFATE_DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.1 | 1.0 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.1 | 9.8 | REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.0 | 0.6 | REACTOME_GAP_JUNCTION_ASSEMBLY | Genes involved in Gap junction assembly |
| 0.0 | 0.6 | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.0 | 0.7 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.0 | 0.4 | REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.0 | 0.5 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.0 | 2.8 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 0.5 | REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.0 | 0.3 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
| 0.0 | 0.3 | REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
| 0.0 | 0.6 | REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS | Genes involved in Regulation of Water Balance by Renal Aquaporins |
| 0.0 | 0.1 | REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR | Genes involved in Thromboxane signalling through TP receptor |
| 0.0 | 0.7 | REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.0 | 0.6 | REACTOME_CGMP_EFFECTS | Genes involved in cGMP effects |
| 0.0 | 1.3 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
| 0.0 | 0.6 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.0 | 0.3 | REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 0.0 | 0.2 | REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.0 | 0.1 | REACTOME_RAP1_SIGNALLING | Genes involved in Rap1 signalling |
| 0.0 | 0.6 | REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS | Genes involved in Transport of Ribonucleoproteins into the Host Nucleus |
| 0.0 | 0.2 | REACTOME_CALNEXIN_CALRETICULIN_CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.0 | 0.5 | REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ | Genes involved in Cyclin E associated events during G1/S transition |
| 0.0 | 0.4 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.0 | 0.3 | REACTOME_FRS2_MEDIATED_CASCADE | Genes involved in FRS2-mediated cascade |
| 0.0 | 0.1 | REACTOME_P38MAPK_EVENTS | Genes involved in p38MAPK events |
| 0.0 | 0.4 | REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.0 | 0.1 | REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |
| 0.0 | 0.3 | REACTOME_EGFR_DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.0 | 0.3 | REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.0 | 0.7 | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.0 | 0.6 | REACTOME_SIGNALING_BY_ERBB2 | Genes involved in Signaling by ERBB2 |
| 0.0 | 0.2 | REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.0 | 0.1 | REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.0 | 0.5 | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.0 | 0.3 | REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE | Genes involved in NGF signalling via TRKA from the plasma membrane |
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