Motif ID: Nfia

Z-value: 2.171


Transcription factors associated with Nfia:

Gene SymbolEntrez IDGene Name
Nfia ENSMUSG00000028565.12 Nfia

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfiamm10_v2_chr4_+_97772734_97772848-0.182.7e-01Click!


Activity profile for motif Nfia.

activity profile for motif Nfia


Sorted Z-values histogram for motif Nfia

Sorted Z-values for motif Nfia



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfia

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_5740885 15.866 ENSMUST00000081496.5
Ltbp3
latent transforming growth factor beta binding protein 3
chr6_+_141524379 13.886 ENSMUST00000032362.9
Slco1c1
solute carrier organic anion transporter family, member 1c1
chr18_+_20665250 12.501 ENSMUST00000075312.3
Ttr
transthyretin
chr10_+_127725392 11.950 ENSMUST00000026466.3
Tac2
tachykinin 2
chr7_+_130936172 11.572 ENSMUST00000006367.7
Htra1
HtrA serine peptidase 1
chr17_-_34972124 10.424 ENSMUST00000087328.2
ENSMUST00000179128.1
Hspa1a

heat shock protein 1A

chr12_+_85473883 10.140 ENSMUST00000021674.6
Fos
FBJ osteosarcoma oncogene
chr7_-_97417730 9.478 ENSMUST00000043077.7
Thrsp
thyroid hormone responsive
chr1_+_42229726 9.435 ENSMUST00000066196.1
Gm9915
predicted gene 9915
chr13_-_97747373 9.241 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr11_-_102897123 9.067 ENSMUST00000067444.3
Gfap
glial fibrillary acidic protein
chr4_+_48045144 8.556 ENSMUST00000030025.3
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr13_+_94173992 8.142 ENSMUST00000121618.1
Lhfpl2
lipoma HMGIC fusion partner-like 2
chr17_+_34969912 7.433 ENSMUST00000173680.1
Gm20481
predicted gene 20481
chr13_-_97747399 7.250 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr2_-_170194033 7.192 ENSMUST00000180625.1
Gm17619
predicted gene, 17619
chr3_-_116129615 6.986 ENSMUST00000029574.8
Vcam1
vascular cell adhesion molecule 1
chr10_+_58813359 6.977 ENSMUST00000135526.2
ENSMUST00000153031.1
Sh3rf3

SH3 domain containing ring finger 3

chr14_-_118052235 6.744 ENSMUST00000022725.2
Dct
dopachrome tautomerase
chr1_+_51289106 6.697 ENSMUST00000051572.6
Sdpr
serum deprivation response
chr17_+_34564268 6.624 ENSMUST00000015612.7
Notch4
notch 4
chr11_-_102897146 6.449 ENSMUST00000077902.4
Gfap
glial fibrillary acidic protein
chr2_-_155945282 6.337 ENSMUST00000040162.2
Gdf5
growth differentiation factor 5
chr11_-_77894096 6.233 ENSMUST00000017597.4
Pipox
pipecolic acid oxidase
chr17_-_34959232 6.062 ENSMUST00000165202.1
ENSMUST00000172753.1
Hspa1b

heat shock protein 1B

chr3_+_89520152 5.646 ENSMUST00000000811.7
Kcnn3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr2_+_32646586 5.552 ENSMUST00000009705.7
ENSMUST00000167841.1
Eng

endoglin

chr5_+_66968559 5.424 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chr11_+_61485431 5.360 ENSMUST00000064783.3
ENSMUST00000040522.6
Mfap4

microfibrillar-associated protein 4

chr6_+_17306335 5.172 ENSMUST00000007799.6
ENSMUST00000115456.1
ENSMUST00000115455.2
ENSMUST00000130505.1
Cav1



caveolin 1, caveolae protein



chr7_-_120202104 5.088 ENSMUST00000033198.5
Crym
crystallin, mu
chr8_+_84723003 5.052 ENSMUST00000098571.4
G430095P16Rik
RIKEN cDNA G430095P16 gene
chr2_-_77703252 5.039 ENSMUST00000171063.1
Zfp385b
zinc finger protein 385B
chr4_-_64046925 5.035 ENSMUST00000107377.3
Tnc
tenascin C
chr6_-_125313844 5.026 ENSMUST00000032489.7
Ltbr
lymphotoxin B receptor
chr11_+_78324200 4.934 ENSMUST00000102478.3
Aldoc
aldolase C, fructose-bisphosphate
chr5_-_124352233 4.916 ENSMUST00000111472.1
Cdk2ap1
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr2_-_114052804 4.912 ENSMUST00000090269.6
Actc1
actin, alpha, cardiac muscle 1
chr12_+_84009481 4.841 ENSMUST00000168120.1
Acot1
acyl-CoA thioesterase 1
chr7_+_78578830 4.779 ENSMUST00000064591.4
Gm9885
predicted gene 9885
chr2_-_25469742 4.675 ENSMUST00000114259.2
ENSMUST00000015234.6
Ptgds

prostaglandin D2 synthase (brain)

chr7_+_45017953 4.602 ENSMUST00000044111.7
Rras
Harvey rat sarcoma oncogene, subgroup R
chr2_+_122147680 4.594 ENSMUST00000102476.4
B2m
beta-2 microglobulin
chr4_-_148287927 4.591 ENSMUST00000047720.8
Ptchd2
patched domain containing 2
chr5_+_66968416 4.545 ENSMUST00000038188.7
Limch1
LIM and calponin homology domains 1
chr11_+_3330401 4.512 ENSMUST00000045153.4
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr1_-_45503282 4.488 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chr4_-_133967953 4.378 ENSMUST00000102553.4
Hmgn2
high mobility group nucleosomal binding domain 2
chr11_+_3330781 4.333 ENSMUST00000136536.1
ENSMUST00000093399.4
Pik3ip1

phosphoinositide-3-kinase interacting protein 1

chr4_+_88094599 4.308 ENSMUST00000097992.3
Focad
focadhesin
chr6_-_54593139 4.292 ENSMUST00000046520.6
Fkbp14
FK506 binding protein 14
chr3_+_94933041 4.207 ENSMUST00000090839.5
Selenbp1
selenium binding protein 1
chr2_+_85136355 4.203 ENSMUST00000057019.7
Aplnr
apelin receptor
chr7_-_46179929 4.177 ENSMUST00000033123.6
Abcc8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr4_+_11704439 4.169 ENSMUST00000108304.2
Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chr11_-_114795888 4.158 ENSMUST00000000206.3
Btbd17
BTB (POZ) domain containing 17
chr6_-_115251839 4.077 ENSMUST00000032462.6
Timp4
tissue inhibitor of metalloproteinase 4
chr13_-_23622502 4.027 ENSMUST00000062045.2
Hist1h1e
histone cluster 1, H1e
chr2_+_33216051 3.995 ENSMUST00000004208.5
Angptl2
angiopoietin-like 2
chr16_-_85803106 3.946 ENSMUST00000023610.8
Adamts1
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1
chr2_-_25470031 3.926 ENSMUST00000114251.1
Ptgds
prostaglandin D2 synthase (brain)
chr3_-_108226598 3.919 ENSMUST00000029486.7
ENSMUST00000156371.1
ENSMUST00000141387.1
Sypl2


synaptophysin-like 2


chr2_+_25180737 3.859 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr17_-_25570678 3.850 ENSMUST00000025003.3
ENSMUST00000173447.1
Sox8

SRY-box containing gene 8

chr6_+_125552948 3.777 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr15_+_10952332 3.741 ENSMUST00000022853.8
ENSMUST00000110523.1
C1qtnf3

C1q and tumor necrosis factor related protein 3

chr14_+_19751257 3.726 ENSMUST00000022340.3
Nid2
nidogen 2
chr10_+_57784859 3.710 ENSMUST00000020024.5
Fabp7
fatty acid binding protein 7, brain
chr3_-_90514250 3.660 ENSMUST00000107340.1
ENSMUST00000060738.8
S100a1

S100 calcium binding protein A1

chr11_-_84068357 3.660 ENSMUST00000100705.4
Dusp14
dual specificity phosphatase 14
chr7_+_99466004 3.660 ENSMUST00000037359.2
Klhl35
kelch-like 35
chr3_+_90537306 3.626 ENSMUST00000107335.1
S100a16
S100 calcium binding protein A16
chr3_+_66219909 3.606 ENSMUST00000029421.5
Ptx3
pentraxin related gene
chr1_-_172219715 3.600 ENSMUST00000170700.1
ENSMUST00000003554.4
Casq1

calsequestrin 1

chr6_+_112273758 3.595 ENSMUST00000032376.5
Lmcd1
LIM and cysteine-rich domains 1
chr1_-_163725123 3.578 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr14_+_32028989 3.507 ENSMUST00000022460.4
Galnt15
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
chr7_-_80403315 3.499 ENSMUST00000147150.1
Furin
furin (paired basic amino acid cleaving enzyme)
chr3_+_90537242 3.488 ENSMUST00000098911.3
S100a16
S100 calcium binding protein A16
chr17_+_86753900 3.484 ENSMUST00000024954.9
Epas1
endothelial PAS domain protein 1
chrX_-_142306170 3.435 ENSMUST00000134825.2
Kcne1l
potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene
chr7_-_78577771 3.404 ENSMUST00000039438.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr14_+_101840602 3.394 ENSMUST00000159314.1
Lmo7
LIM domain only 7
chr4_-_133967893 3.392 ENSMUST00000100472.3
ENSMUST00000136327.1
Hmgn2

high mobility group nucleosomal binding domain 2

chr4_+_137468767 3.359 ENSMUST00000030547.8
ENSMUST00000171332.1
Hspg2

perlecan (heparan sulfate proteoglycan 2)

chr11_+_3332426 3.351 ENSMUST00000136474.1
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr5_+_118169712 3.324 ENSMUST00000054836.6
Hrk
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr4_-_118489755 3.269 ENSMUST00000184261.1
Tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr2_+_133552159 3.245 ENSMUST00000028836.6
Bmp2
bone morphogenetic protein 2
chr5_-_104114088 3.170 ENSMUST00000031249.3
Sparcl1
SPARC-like 1
chr10_+_116301374 3.167 ENSMUST00000092167.5
Ptprb
protein tyrosine phosphatase, receptor type, B
chr6_+_115134899 3.163 ENSMUST00000009538.5
ENSMUST00000169345.1
Syn2

synapsin II

chr5_+_149411749 3.155 ENSMUST00000093110.5
Medag
mesenteric estrogen dependent adipogenesis
chr1_-_162898665 3.143 ENSMUST00000111510.1
ENSMUST00000045902.6
Fmo2

flavin containing monooxygenase 2

chr17_-_72603709 3.143 ENSMUST00000086639.4
Alk
anaplastic lymphoma kinase
chr11_-_84068554 3.140 ENSMUST00000164891.1
Dusp14
dual specificity phosphatase 14
chr7_-_25788635 3.117 ENSMUST00000002677.4
ENSMUST00000085948.4
Axl

AXL receptor tyrosine kinase

chr11_-_100411874 3.113 ENSMUST00000141840.1
Leprel4
leprecan-like 4
chr15_+_79892397 3.100 ENSMUST00000175714.1
ENSMUST00000109620.3
ENSMUST00000165537.1
Apobec3


apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3


chrX_+_10485121 3.074 ENSMUST00000076354.6
ENSMUST00000115526.1
Tspan7

tetraspanin 7

chr1_+_180330470 3.063 ENSMUST00000070181.6
Itpkb
inositol 1,4,5-trisphosphate 3-kinase B
chr7_+_114745685 3.054 ENSMUST00000136645.1
ENSMUST00000169913.1
Insc

inscuteable homolog (Drosophila)

chr5_+_64812336 3.052 ENSMUST00000166409.1
Klf3
Kruppel-like factor 3 (basic)
chr2_+_59612034 3.025 ENSMUST00000112568.1
ENSMUST00000037526.4
Tanc1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr16_+_43510267 2.992 ENSMUST00000114695.2
Zbtb20
zinc finger and BTB domain containing 20
chr17_-_73950172 2.938 ENSMUST00000024866.4
Xdh
xanthine dehydrogenase
chr11_+_78499087 2.914 ENSMUST00000017488.4
Vtn
vitronectin
chr4_-_155992604 2.888 ENSMUST00000052185.3
B3galt6
UDP-Gal:betaGal beta 1,3-galactosyltransferase, polypeptide 6
chr4_-_147936713 2.827 ENSMUST00000105712.1
ENSMUST00000019199.7
Plod1

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1

chr1_-_56969864 2.824 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr13_+_38345716 2.813 ENSMUST00000171970.1
Bmp6
bone morphogenetic protein 6
chr7_+_27605797 2.801 ENSMUST00000143499.1
ENSMUST00000108343.1
Akt2

thymoma viral proto-oncogene 2

chr8_+_57455898 2.796 ENSMUST00000034023.3
Scrg1
scrapie responsive gene 1
chr12_+_37880700 2.794 ENSMUST00000040500.7
Dgkb
diacylglycerol kinase, beta
chr13_+_21722057 2.774 ENSMUST00000110476.3
Hist1h2bm
histone cluster 1, H2bm
chr6_+_17306415 2.774 ENSMUST00000150901.1
Cav1
caveolin 1, caveolae protein
chr15_+_79892436 2.773 ENSMUST00000175752.1
ENSMUST00000176325.1
Apobec3

apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3

chr13_-_71963713 2.766 ENSMUST00000077337.8
Irx1
Iroquois related homeobox 1 (Drosophila)
chr1_-_56969827 2.757 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr1_-_190170178 2.755 ENSMUST00000177288.1
Prox1
prospero-related homeobox 1
chr15_-_3583191 2.735 ENSMUST00000069451.4
Ghr
growth hormone receptor
chr15_+_25773985 2.723 ENSMUST00000125667.1
Myo10
myosin X
chr19_-_8929323 2.714 ENSMUST00000096242.3
Rom1
rod outer segment membrane protein 1
chr3_+_138277489 2.708 ENSMUST00000004232.9
Adh1
alcohol dehydrogenase 1 (class I)
chrX_+_166344692 2.703 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
Gpm6b





glycoprotein m6b





chr9_+_107975529 2.697 ENSMUST00000035216.4
Uba7
ubiquitin-like modifier activating enzyme 7
chr3_+_127633134 2.683 ENSMUST00000029587.7
Neurog2
neurogenin 2
chr7_+_27605847 2.679 ENSMUST00000051356.5
Akt2
thymoma viral proto-oncogene 2
chr6_+_134920401 2.670 ENSMUST00000067327.4
ENSMUST00000003115.6
Cdkn1b

cyclin-dependent kinase inhibitor 1B

chr7_+_120843551 2.660 ENSMUST00000106489.1
ENSMUST00000143279.1
Eef2k

eukaryotic elongation factor-2 kinase

chr11_-_116110211 2.650 ENSMUST00000106441.1
ENSMUST00000021120.5
Trim47

tripartite motif-containing 47

chr6_+_138140298 2.644 ENSMUST00000008684.4
Mgst1
microsomal glutathione S-transferase 1
chr3_+_137341103 2.638 ENSMUST00000119475.1
Emcn
endomucin
chr14_+_101840501 2.634 ENSMUST00000159026.1
Lmo7
LIM domain only 7
chr15_-_78405824 2.630 ENSMUST00000058659.7
Tst
thiosulfate sulfurtransferase, mitochondrial
chr17_-_34000257 2.621 ENSMUST00000087189.6
ENSMUST00000173075.1
ENSMUST00000172760.1
ENSMUST00000172912.1
ENSMUST00000025181.10
H2-K1




histocompatibility 2, K1, K region




chr1_+_169928648 2.621 ENSMUST00000094348.3
1700084C01Rik
RIKEN cDNA 1700084C01 gene
chr8_-_71395794 2.610 ENSMUST00000049184.7
Ushbp1
Usher syndrome 1C binding protein 1
chr14_+_13454010 2.591 ENSMUST00000112656.2
Synpr
synaptoporin
chr16_-_36784784 2.566 ENSMUST00000165531.1
Slc15a2
solute carrier family 15 (H+/peptide transporter), member 2
chr11_-_62539257 2.549 ENSMUST00000018653.1
Cenpv
centromere protein V
chr5_+_66968961 2.545 ENSMUST00000132991.1
Limch1
LIM and calponin homology domains 1
chr3_+_86084434 2.529 ENSMUST00000107664.2
Sh3d19
SH3 domain protein D19
chr9_-_79718518 2.523 ENSMUST00000071750.6
Col12a1
collagen, type XII, alpha 1
chr2_+_152143552 2.517 ENSMUST00000089112.5
Tcf15
transcription factor 15
chr2_+_105668935 2.506 ENSMUST00000142772.1
Pax6
paired box gene 6
chr6_+_138140521 2.504 ENSMUST00000120939.1
ENSMUST00000120302.1
Mgst1

microsomal glutathione S-transferase 1

chr1_+_185454803 2.498 ENSMUST00000061093.6
Slc30a10
solute carrier family 30, member 10
chr4_-_133967235 2.479 ENSMUST00000123234.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr17_-_35697971 2.472 ENSMUST00000146472.1
Ddr1
discoidin domain receptor family, member 1
chr1_-_190169399 2.461 ENSMUST00000010319.7
Prox1
prospero-related homeobox 1
chr12_+_75308308 2.452 ENSMUST00000118602.1
ENSMUST00000118966.1
ENSMUST00000055390.5
Rhoj


ras homolog gene family, member J


chr2_-_127482499 2.447 ENSMUST00000088538.5
Kcnip3
Kv channel interacting protein 3, calsenilin
chr8_-_78436640 2.443 ENSMUST00000034115.3
Pou4f2
POU domain, class 4, transcription factor 2
chr15_-_3583146 2.435 ENSMUST00000110698.2
Ghr
growth hormone receptor
chr2_-_158146385 2.435 ENSMUST00000103122.3
Tgm2
transglutaminase 2, C polypeptide
chr8_-_105484350 2.422 ENSMUST00000044286.5
Zdhhc1
zinc finger, DHHC domain containing 1
chr11_+_109485606 2.411 ENSMUST00000106697.1
Arsg
arylsulfatase G
chr9_-_51278540 2.406 ENSMUST00000114427.3
Gm684
predicted gene 684
chr5_+_21543525 2.392 ENSMUST00000035651.4
Lrrc17
leucine rich repeat containing 17
chr17_-_47016956 2.371 ENSMUST00000165525.1
Gm16494
predicted gene 16494
chr11_+_49609263 2.345 ENSMUST00000020617.2
Flt4
FMS-like tyrosine kinase 4
chr4_-_4138432 2.344 ENSMUST00000070375.7
Penk
preproenkephalin
chr6_+_117168535 2.337 ENSMUST00000112866.1
ENSMUST00000112871.1
ENSMUST00000073043.4
Cxcl12


chemokine (C-X-C motif) ligand 12


chr17_+_35424870 2.315 ENSMUST00000113879.3
H2-Q6
histocompatibility 2, Q region locus 6
chr16_+_23290464 2.306 ENSMUST00000115335.1
St6gal1
beta galactoside alpha 2,6 sialyltransferase 1
chr5_+_123015010 2.304 ENSMUST00000121652.1
ENSMUST00000051016.4
Orai1

ORAI calcium release-activated calcium modulator 1

chr1_-_77515048 2.294 ENSMUST00000027451.6
Epha4
Eph receptor A4
chr2_+_105668888 2.291 ENSMUST00000111086.4
ENSMUST00000111087.3
Pax6

paired box gene 6

chr16_+_91269759 2.286 ENSMUST00000056882.5
Olig1
oligodendrocyte transcription factor 1
chr1_+_169929929 2.285 ENSMUST00000175731.1
1700084C01Rik
RIKEN cDNA 1700084C01 gene
chr14_-_118237016 2.281 ENSMUST00000170662.1
Sox21
SRY-box containing gene 21
chr4_-_119422355 2.271 ENSMUST00000106316.1
ENSMUST00000030385.6
Ppcs

phosphopantothenoylcysteine synthetase

chr14_+_55491062 2.269 ENSMUST00000076236.5
Lrrc16b
leucine rich repeat containing 16B
chr1_-_191183244 2.241 ENSMUST00000027941.8
Atf3
activating transcription factor 3
chr4_+_109978004 2.222 ENSMUST00000061187.3
Dmrta2
doublesex and mab-3 related transcription factor like family A2
chr12_+_36314160 2.201 ENSMUST00000041407.5
Sostdc1
sclerostin domain containing 1
chr2_-_116065798 2.200 ENSMUST00000110907.1
ENSMUST00000110908.2
Meis2

Meis homeobox 2

chr9_-_103222063 2.171 ENSMUST00000170904.1
Trf
transferrin
chr5_+_66745835 2.143 ENSMUST00000101164.4
ENSMUST00000118242.1
ENSMUST00000119854.1
ENSMUST00000117601.1
Limch1



LIM and calponin homology domains 1



chr10_+_17723220 2.141 ENSMUST00000038107.7
Cited2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chrX_+_99975570 2.139 ENSMUST00000113779.1
ENSMUST00000113776.1
ENSMUST00000113775.1
ENSMUST00000113780.1
ENSMUST00000113778.1
ENSMUST00000113781.1
ENSMUST00000113783.1
ENSMUST00000071453.2
ENSMUST00000113777.1
Eda








ectodysplasin-A








chr7_+_35119285 2.132 ENSMUST00000042985.9
Cebpa
CCAAT/enhancer binding protein (C/EBP), alpha
chr5_-_115436508 2.129 ENSMUST00000078701.3
4930430O22Rik
RIKEN cDNA 4930430O22 gene
chr11_+_35121126 2.113 ENSMUST00000069837.3
Slit3
slit homolog 3 (Drosophila)
chr16_-_85550417 2.107 ENSMUST00000175700.1
ENSMUST00000114174.2
Cyyr1

cysteine and tyrosine-rich protein 1

chr7_+_113207465 2.091 ENSMUST00000047321.7
Arntl
aryl hydrocarbon receptor nuclear translocator-like
chr4_-_42661893 2.090 ENSMUST00000108006.3
Il11ra2
interleukin 11 receptor, alpha chain 2
chr17_+_82539258 2.083 ENSMUST00000097278.3
Gm6594
predicted pseudogene 6594
chr6_+_108213086 2.060 ENSMUST00000032192.6
Itpr1
inositol 1,4,5-trisphosphate receptor 1
chr12_-_75735729 2.060 ENSMUST00000021450.4
Sgpp1
sphingosine-1-phosphate phosphatase 1
chr7_-_45091713 2.058 ENSMUST00000141576.1
Rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr5_+_24364804 2.050 ENSMUST00000030834.4
ENSMUST00000115090.1
Nos3

nitric oxide synthase 3, endothelial cell

chr19_+_5088534 2.020 ENSMUST00000025811.4
Yif1a
Yip1 interacting factor homolog A (S. cerevisiae)
chr12_-_84876479 2.007 ENSMUST00000163189.1
ENSMUST00000110254.2
ENSMUST00000002073.6
Ltbp2


latent transforming growth factor beta binding protein 2


chr5_+_111733924 2.000 ENSMUST00000180627.1
Gm26897
predicted gene, 26897
chr7_-_78578308 1.996 ENSMUST00000039431.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr4_-_108032069 1.994 ENSMUST00000106709.2
Podn
podocan
chr8_+_71406003 1.979 ENSMUST00000119976.1
ENSMUST00000120725.1
Ankle1

ankyrin repeat and LEM domain containing 1

chr9_-_121277160 1.976 ENSMUST00000051479.6
ENSMUST00000171923.1
Ulk4

unc-51-like kinase 4


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.6 5.6 GO:1905072 cardiac jelly development(GO:1905072)
5.3 15.9 GO:1902460 transforming growth factor beta activation(GO:0036363) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
3.5 17.6 GO:0070327 thyroid hormone transport(GO:0070327)
3.2 3.2 GO:0003134 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134)
3.0 11.9 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
2.9 8.6 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
2.2 15.5 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
2.0 10.1 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
1.9 11.6 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
1.9 3.9 GO:0072197 ureter morphogenesis(GO:0072197)
1.9 5.7 GO:0006553 lysine metabolic process(GO:0006553)
1.8 5.4 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
1.7 8.6 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
1.7 5.0 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
1.6 7.9 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
1.5 4.5 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
1.4 4.3 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
1.4 4.2 GO:0002030 inhibitory G-protein coupled receptor phosphorylation(GO:0002030)
1.4 4.2 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
1.4 9.7 GO:0021847 ventricular zone neuroblast division(GO:0021847)
1.3 2.6 GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
1.3 5.2 GO:0000255 allantoin metabolic process(GO:0000255)
1.3 9.0 GO:0048251 elastic fiber assembly(GO:0048251)
1.3 5.1 GO:0006982 response to lipid hydroperoxide(GO:0006982) cellular response to lipid hydroperoxide(GO:0071449)
1.3 6.3 GO:0060591 chondroblast differentiation(GO:0060591)
1.2 8.6 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
1.2 13.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
1.2 3.6 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
1.1 4.6 GO:0002481 antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481) regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759)
1.1 4.5 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
1.1 2.2 GO:1903984 regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
1.1 3.3 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
1.1 1.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
1.0 3.1 GO:0097350 neutrophil clearance(GO:0097350)
1.0 1.0 GO:0003162 atrioventricular node development(GO:0003162)
1.0 2.9 GO:1900747 xanthine metabolic process(GO:0046110) negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
1.0 5.9 GO:0032196 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) transposition(GO:0032196)
1.0 4.8 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
0.9 2.8 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.9 3.7 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.9 0.9 GO:0021593 rhombomere morphogenesis(GO:0021593)
0.9 1.9 GO:0030210 heparin biosynthetic process(GO:0030210)
0.9 5.5 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.9 2.6 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.9 3.5 GO:0090472 dibasic protein processing(GO:0090472)
0.9 1.7 GO:0045168 cell-cell signaling involved in cell fate commitment(GO:0045168)
0.9 9.5 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.8 2.5 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.8 2.4 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.8 3.1 GO:0072592 oxygen metabolic process(GO:0072592)
0.8 3.1 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.7 6.0 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.7 3.7 GO:0090343 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) positive regulation of cell aging(GO:0090343)
0.7 5.9 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.7 2.2 GO:0060648 mammary gland bud morphogenesis(GO:0060648) negative regulation of determination of dorsal identity(GO:2000016)
0.7 3.6 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.7 2.2 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.7 2.1 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.7 2.1 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.7 3.5 GO:1903181 regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
0.7 2.8 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.7 11.7 GO:0035994 response to muscle stretch(GO:0035994)
0.6 12.2 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.6 2.5 GO:1902724 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.6 3.7 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.6 1.2 GO:2000282 regulation of cellular amino acid biosynthetic process(GO:2000282)
0.6 0.6 GO:2000468 regulation of peroxidase activity(GO:2000468)
0.6 3.6 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.6 2.3 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.6 2.3 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.6 6.4 GO:0061032 visceral serous pericardium development(GO:0061032)
0.6 2.3 GO:2000110 protein sialylation(GO:1990743) negative regulation of macrophage apoptotic process(GO:2000110)
0.6 5.6 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.5 1.1 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.5 0.5 GO:0097278 complement-dependent cytotoxicity(GO:0097278)
0.5 2.1 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.5 1.6 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.5 1.0 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.5 2.1 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.5 2.6 GO:0042891 antibiotic transport(GO:0042891) dipeptide transport(GO:0042938)
0.5 1.5 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.5 2.0 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.5 4.9 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.5 1.5 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.5 0.5 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.5 3.4 GO:0016584 nucleosome positioning(GO:0016584)
0.5 2.4 GO:1902869 regulation of amacrine cell differentiation(GO:1902869)
0.5 2.4 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.5 1.4 GO:0048014 Tie signaling pathway(GO:0048014)
0.5 2.4 GO:0048539 bone marrow development(GO:0048539)
0.5 3.7 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.5 3.7 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.4 1.8 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.4 1.3 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.4 1.3 GO:0070428 granuloma formation(GO:0002432) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070432)
0.4 0.9 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.4 1.7 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.4 1.3 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.4 4.2 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.4 0.4 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.4 1.2 GO:1902524 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.4 2.1 GO:0042045 epithelial fluid transport(GO:0042045)
0.4 0.8 GO:1903596 regulation of gap junction assembly(GO:1903596)
0.4 1.2 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.4 1.2 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.4 2.7 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.4 1.1 GO:0071500 cellular response to nitrosative stress(GO:0071500)
0.4 3.7 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.4 1.5 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.4 2.5 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.4 4.7 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.4 0.7 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.4 1.8 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.4 2.2 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.4 2.5 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.4 0.4 GO:0097212 lysosomal membrane organization(GO:0097212)
0.3 2.1 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.3 1.4 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.3 1.0 GO:0006592 ornithine biosynthetic process(GO:0006592)
0.3 0.3 GO:0032276 regulation of gonadotropin secretion(GO:0032276)
0.3 2.7 GO:0048149 behavioral response to ethanol(GO:0048149)
0.3 2.7 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.3 2.3 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.3 0.7 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.3 1.7 GO:1905169 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.3 2.0 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.3 1.9 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.3 1.6 GO:0034421 post-translational protein acetylation(GO:0034421)
0.3 1.0 GO:0072092 ureteric bud invasion(GO:0072092)
0.3 1.3 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.3 0.6 GO:2000338 chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.3 0.9 GO:0003289 atrial septum primum morphogenesis(GO:0003289)
0.3 0.9 GO:0071873 response to norepinephrine(GO:0071873)
0.3 0.9 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.3 1.2 GO:0035898 parathyroid hormone secretion(GO:0035898)
0.3 0.9 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.3 0.9 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.3 3.9 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.3 2.9 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.3 5.8 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.3 1.7 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.3 0.8 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.3 1.1 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.3 2.1 GO:0000050 urea cycle(GO:0000050) urea metabolic process(GO:0019627)
0.3 1.3 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.3 5.7 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.3 1.0 GO:0010756 regulation of plasminogen activation(GO:0010755) positive regulation of plasminogen activation(GO:0010756)
0.2 1.5 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.2 1.9 GO:0032836 glomerular basement membrane development(GO:0032836)
0.2 1.4 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.2 2.3 GO:0002118 aggressive behavior(GO:0002118)
0.2 0.5 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.2 3.7 GO:0060134 prepulse inhibition(GO:0060134)
0.2 1.2 GO:2001286 regulation of caveolin-mediated endocytosis(GO:2001286)
0.2 0.5 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2 2.4 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.2 2.9 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.2 3.7 GO:0045792 negative regulation of cell size(GO:0045792)
0.2 1.3 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
0.2 1.3 GO:0016266 O-glycan processing(GO:0016266)
0.2 0.2 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.2 0.8 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.2 0.6 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.2 0.6 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.2 1.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.2 0.8 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.2 0.6 GO:1903406 regulation of sodium:potassium-exchanging ATPase activity(GO:1903406)
0.2 0.8 GO:1902512 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.2 1.0 GO:2000427 eosinophil chemotaxis(GO:0048245) positive regulation of apoptotic cell clearance(GO:2000427)
0.2 0.8 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
0.2 0.4 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.2 0.4 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.2 0.6 GO:0060596 regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003256) mammary placode formation(GO:0060596)
0.2 0.9 GO:0006689 ganglioside catabolic process(GO:0006689)
0.2 0.6 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.2 4.4 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.2 1.8 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070)
0.2 1.1 GO:0036089 cleavage furrow formation(GO:0036089)
0.2 1.4 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.2 6.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.2 0.7 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.2 2.5 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.2 0.7 GO:0035811 negative regulation of urine volume(GO:0035811)
0.2 0.7 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2 5.0 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.2 1.0 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.2 1.9 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.2 1.7 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.2 1.5 GO:0090527 actin filament reorganization(GO:0090527)
0.2 0.3 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.2 0.8 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.2 0.3 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.2 0.8 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.2 1.1 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.2 0.6 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.2 1.7 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.2 0.6 GO:0018201 peptidyl-glycine modification(GO:0018201)
0.1 1.8 GO:0048194 Golgi vesicle budding(GO:0048194)
0.1 4.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 2.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 1.5 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 0.9 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.4 GO:0045054 constitutive secretory pathway(GO:0045054)
0.1 1.0 GO:0006105 succinate metabolic process(GO:0006105)
0.1 0.7 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.3 GO:0061209 cell proliferation involved in mesonephros development(GO:0061209) mesenchymal cell proliferation involved in ureteric bud development(GO:0072138)
0.1 1.7 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 1.4 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.1 1.7 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.1 1.5 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.1 0.7 GO:0070166 enamel mineralization(GO:0070166)
0.1 1.2 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 2.3 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 4.9 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.5 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1 0.5 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.1 0.7 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 0.7 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.9 GO:0046549 phenol-containing compound catabolic process(GO:0019336) retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.1 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 3.7 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.1 0.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.9 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 1.5 GO:0045624 positive regulation of T-helper cell differentiation(GO:0045624)
0.1 0.9 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.1 4.0 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.1 2.0 GO:0008206 bile acid metabolic process(GO:0008206)
0.1 4.3 GO:0007520 myoblast fusion(GO:0007520)
0.1 1.0 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.1 0.5 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.1 2.8 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 0.4 GO:0048520 positive regulation of behavior(GO:0048520)
0.1 0.8 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 9.7 GO:0009408 response to heat(GO:0009408)
0.1 1.5 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 1.7 GO:0097435 fibril organization(GO:0097435)
0.1 1.4 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.1 1.8 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 0.1 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.1 0.3 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.1 3.3 GO:0045026 plasma membrane fusion(GO:0045026)
0.1 0.5 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.8 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.4 GO:0015744 succinate transport(GO:0015744)
0.1 0.3 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.1 1.8 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.1 0.6 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.1 3.1 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.1 1.7 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 4.5 GO:0006023 aminoglycan biosynthetic process(GO:0006023)
0.1 0.2 GO:0014010 Schwann cell proliferation(GO:0014010)
0.1 0.5 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.1 2.0 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.1 5.7 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 0.3 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.1 0.3 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.1 3.1 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 0.9 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 1.3 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 0.6 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.1 2.5 GO:0016578 histone deubiquitination(GO:0016578)
0.1 0.3 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.1 1.2 GO:0016322 neuron remodeling(GO:0016322)
0.1 0.5 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.1 0.2 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.6 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1 1.0 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.9 GO:0046051 UTP metabolic process(GO:0046051)
0.1 0.4 GO:0045896 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.1 0.5 GO:0046415 urate metabolic process(GO:0046415)
0.1 1.0 GO:0043277 apoptotic cell clearance(GO:0043277)
0.1 0.4 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.9 GO:0018065 protein-cofactor linkage(GO:0018065)
0.1 1.0 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.3 GO:0046709 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.1 0.8 GO:1904667 negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.1 0.3 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 0.4 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.1 1.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.3 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1 0.5 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 1.9 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 2.9 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.1 0.5 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393) follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 2.2 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.8 GO:0090051 regulation of skeletal muscle fiber development(GO:0048742) negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.1 1.0 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.1 0.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.9 GO:0061098 positive regulation of protein tyrosine kinase activity(GO:0061098)
0.1 1.2 GO:0014904 myotube cell development(GO:0014904)
0.1 0.2 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.1 4.3 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.1 0.3 GO:1903286 regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.1 2.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.2 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.1 0.2 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) DNA replication preinitiation complex assembly(GO:0071163) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.1 GO:0032242 regulation of nucleoside transport(GO:0032242) regulation of neurotrophin production(GO:0032899) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.1 0.4 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 0.2 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.3 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 0.7 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.1 0.3 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.1 1.7 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.1 0.5 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 0.3 GO:0010796 regulation of multivesicular body size(GO:0010796) protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 0.7 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.1 0.5 GO:0000022 mitotic spindle elongation(GO:0000022) spindle midzone assembly(GO:0051255) mitotic spindle midzone assembly(GO:0051256)
0.1 0.5 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.1 1.4 GO:0006298 mismatch repair(GO:0006298)
0.1 0.3 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 0.7 GO:0046548 retinal rod cell development(GO:0046548)
0.1 1.3 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 0.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.3 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1 0.2 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.1 0.6 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.1 1.0 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.1 0.3 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 0.2 GO:1903624 regulation of apoptotic DNA fragmentation(GO:1902510) regulation of DNA catabolic process(GO:1903624)
0.1 0.5 GO:0044381 glucose import in response to insulin stimulus(GO:0044381) regulation of glucose import in response to insulin stimulus(GO:2001273)
0.1 1.5 GO:0042255 ribosome assembly(GO:0042255)
0.1 0.4 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.3 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.1 1.0 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 0.6 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.1 0.4 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1 0.1 GO:0051593 response to folic acid(GO:0051593)
0.1 0.2 GO:0042360 vitamin E metabolic process(GO:0042360)
0.1 1.6 GO:0060135 maternal process involved in female pregnancy(GO:0060135)
0.1 0.8 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 1.6 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.4 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.5 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.2 GO:0000054 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753) rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0 0.8 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.1 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 0.3 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.0 0.3 GO:0014823 response to activity(GO:0014823)
0.0 0.9 GO:0050850 positive regulation of calcium-mediated signaling(GO:0050850)
0.0 3.3 GO:0001889 liver development(GO:0001889)
0.0 0.4 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.9 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.9 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.1 GO:0003340 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340)
0.0 0.1 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 1.0 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.3 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.0 5.0 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 1.8 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.0 1.0 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.6 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.2 GO:1905146 protein catabolic process in the vacuole(GO:0007039) lysosomal protein catabolic process(GO:1905146)
0.0 0.1 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960) mitochondrial RNA 3'-end processing(GO:0000965)
0.0 1.2 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 3.0 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.3 GO:0003085 negative regulation of systemic arterial blood pressure(GO:0003085)
0.0 0.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.2 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.3 GO:0070475 rRNA base methylation(GO:0070475)
0.0 1.4 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.0 0.4 GO:0000423 macromitophagy(GO:0000423)
0.0 0.3 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.3 GO:0070200 establishment of protein localization to telomere(GO:0070200)
0.0 0.2 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.0 1.4 GO:0070206 protein trimerization(GO:0070206)
0.0 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.3 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.8 GO:0019835 cytolysis(GO:0019835)
0.0 0.6 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.1 GO:0050912 detection of chemical stimulus involved in sensory perception(GO:0050907) detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.0 0.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.6 GO:0072337 modified amino acid transport(GO:0072337)
0.0 1.0 GO:0090102 cochlea development(GO:0090102)
0.0 0.5 GO:0042993 positive regulation of transcription factor import into nucleus(GO:0042993)
0.0 0.3 GO:0019884 antigen processing and presentation of exogenous antigen(GO:0019884)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.3 GO:0019430 removal of superoxide radicals(GO:0019430)
0.0 0.5 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.2 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 1.9 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.2 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 1.7 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.3 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.6 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 0.1 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.4 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.1 GO:0031214 biomineral tissue development(GO:0031214)
0.0 0.5 GO:0046324 regulation of glucose import(GO:0046324)
0.0 0.8 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.2 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
0.0 0.1 GO:0033108 mitochondrial respiratory chain complex assembly(GO:0033108)
0.0 0.5 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.6 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.8 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 1.3 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.2 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.0 0.9 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.2 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.6 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 0.2 GO:0044065 regulation of respiratory system process(GO:0044065)
0.0 0.1 GO:0016128 phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129)
0.0 0.0 GO:0032769 negative regulation of monooxygenase activity(GO:0032769) negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.4 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.0 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.7 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.5 GO:0006040 amino sugar metabolic process(GO:0006040)
0.0 0.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.0 GO:0090282 trophectodermal cellular morphogenesis(GO:0001831) positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931) positive regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0090282)
0.0 0.5 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.0 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.0 0.1 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 0.3 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 15.5 GO:0097450 astrocyte end-foot(GO:0097450)
1.8 11.0 GO:0035976 AP1 complex(GO:0035976)
1.8 5.4 GO:0071953 elastic fiber(GO:0071953)
1.5 4.5 GO:0005588 collagen type V trimer(GO:0005588)
1.1 2.1 GO:0036488 CHOP-C/EBP complex(GO:0036488)
1.0 4.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.9 11.1 GO:0042612 MHC class I protein complex(GO:0042612)
0.9 3.6 GO:0014802 terminal cisterna(GO:0014802)
0.9 4.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.8 2.5 GO:0030934 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
0.7 2.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.6 8.0 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.6 2.3 GO:0032280 symmetric synapse(GO:0032280)
0.6 2.9 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.5 3.8 GO:0005638 lamin filament(GO:0005638)
0.4 5.7 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.4 1.5 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.4 1.9 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.4 3.9 GO:0031931 TORC1 complex(GO:0031931)
0.3 1.0 GO:0044299 C-fiber(GO:0044299)
0.3 5.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.3 1.3 GO:0032021 NELF complex(GO:0032021)
0.3 2.1 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.3 5.7 GO:0005605 basal lamina(GO:0005605)
0.3 6.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.3 2.2 GO:0097433 dense body(GO:0097433)
0.3 2.1 GO:0033391 chromatoid body(GO:0033391)
0.3 9.1 GO:0051233 spindle midzone(GO:0051233)
0.3 21.6 GO:0072562 blood microparticle(GO:0072562)
0.3 1.0 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.2 2.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 1.7 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.2 3.8 GO:0005614 interstitial matrix(GO:0005614)
0.2 2.3 GO:0000138 Golgi trans cisterna(GO:0000138)
0.2 1.8 GO:0042589 zymogen granule membrane(GO:0042589)
0.2 3.5 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.2 1.1 GO:0001652 granular component(GO:0001652)
0.2 2.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.2 0.8 GO:0035189 Rb-E2F complex(GO:0035189)
0.2 1.0 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2 3.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 1.8 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.2 1.0 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.2 0.6 GO:0044753 amphisome(GO:0044753)
0.2 0.8 GO:0005594 collagen type IX trimer(GO:0005594)
0.2 0.6 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.2 1.9 GO:0032591 dendritic spine membrane(GO:0032591)
0.2 0.6 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.2 0.7 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2 10.0 GO:0005581 collagen trimer(GO:0005581)
0.2 1.6 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.2 0.9 GO:0014704 intercalated disc(GO:0014704)
0.2 0.3 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.2 1.0 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2 6.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.2 0.9 GO:0042588 zymogen granule(GO:0042588)
0.2 5.0 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 16.0 GO:0030175 filopodium(GO:0030175)
0.1 2.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 3.1 GO:0043657 host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1 0.4 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 0.4 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 1.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.7 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 6.3 GO:0005604 basement membrane(GO:0005604)
0.1 2.0 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 1.0 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 4.4 GO:0000786 nucleosome(GO:0000786)
0.1 37.5 GO:0031012 extracellular matrix(GO:0031012)
0.1 0.7 GO:0005859 muscle myosin complex(GO:0005859)
0.1 0.9 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 1.9 GO:0097440 apical dendrite(GO:0097440)
0.1 0.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 1.7 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 6.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.9 GO:0030478 actin cap(GO:0030478)
0.1 2.5 GO:0005902 microvillus(GO:0005902)
0.1 3.4 GO:0097546 ciliary base(GO:0097546)
0.1 0.8 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.5 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 4.5 GO:0031985 Golgi cisterna(GO:0031985)
0.1 0.7 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.1 0.3 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 0.5 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 1.1 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.3 GO:0000814 ESCRT II complex(GO:0000814)
0.1 0.9 GO:0031528 microvillus membrane(GO:0031528)
0.1 0.5 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 0.9 GO:0031045 dense core granule(GO:0031045)
0.1 2.9 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 5.0 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 0.7 GO:0022626 cytosolic ribosome(GO:0022626)
0.1 1.1 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 1.0 GO:0031143 pseudopodium(GO:0031143)
0.1 0.2 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1 9.8 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.1 5.1 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.1 7.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 1.9 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 3.1 GO:0045177 apical part of cell(GO:0045177)
0.1 0.6 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.8 GO:0070938 contractile ring(GO:0070938)
0.1 1.0 GO:0016589 NURF complex(GO:0016589)
0.1 3.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 15.6 GO:0005667 transcription factor complex(GO:0005667)
0.1 0.4 GO:0030914 STAGA complex(GO:0030914)
0.1 0.5 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 0.3 GO:0070876 SOSS complex(GO:0070876)
0.1 3.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.4 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.2 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 1.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 3.6 GO:0005901 caveola(GO:0005901)
0.0 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 1.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 16.1 GO:0005925 focal adhesion(GO:0005925)
0.0 0.8 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 0.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.3 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 2.3 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 1.4 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 1.5 GO:0031526 brush border membrane(GO:0031526)
0.0 0.8 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 1.8 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 7.8 GO:0005769 early endosome(GO:0005769)
0.0 7.0 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 9.3 GO:0043235 receptor complex(GO:0043235)
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 1.2 GO:0015935 small ribosomal subunit(GO:0015935)
0.0 0.5 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.3 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.5 GO:0030673 axolemma(GO:0030673)
0.0 0.8 GO:0031594 neuromuscular junction(GO:0031594)
0.0 13.5 GO:0005615 extracellular space(GO:0005615)
0.0 0.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.6 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.5 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 0.7 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.5 GO:0012506 vesicle membrane(GO:0012506)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 0.7 GO:0031519 PcG protein complex(GO:0031519)
0.0 1.5 GO:0000922 spindle pole(GO:0000922)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.0 GO:0031430 M band(GO:0031430)
0.0 0.5 GO:0005657 replication fork(GO:0005657)
0.0 0.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.4 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 5.1 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.5 GO:0005871 kinesin complex(GO:0005871)
0.0 0.7 GO:0010008 endosome membrane(GO:0010008)
0.0 0.0 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:0005774 vacuolar membrane(GO:0005774)
0.0 0.3 GO:0090544 BAF-type complex(GO:0090544)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.2 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
3.5 13.9 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
2.2 8.6 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
2.0 17.6 GO:0070324 thyroid hormone binding(GO:0070324)
1.7 7.0 GO:0008131 primary amine oxidase activity(GO:0008131)
1.6 7.9 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
1.6 6.2 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
1.5 4.5 GO:0004686 elongation factor-2 kinase activity(GO:0004686)
1.5 5.9 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
1.4 13.0 GO:0036122 BMP binding(GO:0036122)
1.4 5.6 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
1.1 5.4 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.9 7.3 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.9 2.7 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.9 2.6 GO:0042936 dipeptide transporter activity(GO:0042936)
0.8 5.0 GO:0045545 syndecan binding(GO:0045545)
0.8 4.9 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.8 3.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.8 3.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.8 3.8 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.7 2.9 GO:0043546 molybdenum ion binding(GO:0030151) molybdopterin cofactor binding(GO:0043546)
0.7 6.6 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.7 2.2 GO:0098809 nitrite reductase activity(GO:0098809)
0.7 15.9 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.7 2.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.7 2.0 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.6 7.5 GO:0050693 LBD domain binding(GO:0050693)
0.6 0.6 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.6 2.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.6 6.1 GO:0070700 BMP receptor binding(GO:0070700)
0.6 3.4 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.5 2.7 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.5 2.6 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.5 2.6 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.5 3.6 GO:0001849 complement component C1q binding(GO:0001849)
0.5 1.0 GO:0070052 collagen V binding(GO:0070052)
0.5 11.1 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.5 6.6 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.5 6.5 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.5 7.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.5 1.5 GO:0004415 hyalurononglucosaminidase activity(GO:0004415) hyaluronan synthase activity(GO:0050501)
0.5 2.0 GO:0008410 CoA-transferase activity(GO:0008410)
0.5 2.9 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.5 2.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.5 1.8 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.4 4.0 GO:0032564 dATP binding(GO:0032564)
0.4 3.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.4 3.8 GO:0019865 immunoglobulin binding(GO:0019865)
0.4 1.2 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.4 14.9 GO:0070412 R-SMAD binding(GO:0070412)
0.4 2.3 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004) PH domain binding(GO:0042731)
0.4 1.9 GO:1990239 steroid hormone binding(GO:1990239)
0.4 1.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.3 1.0 GO:0017084 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
0.3 1.0 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.3 2.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.3 3.0 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.3 2.9 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.3 2.9 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.3 2.5 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.3 1.3 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.3 1.6 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.3 3.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 2.2 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.3 4.8 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.3 0.6 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.3 3.8 GO:0050897 cobalt ion binding(GO:0050897)
0.3 0.9 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.3 0.9 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.3 2.0 GO:0001515 opioid peptide activity(GO:0001515)
0.3 3.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.3 2.5 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.3 2.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.3 1.6 GO:0050786 RAGE receptor binding(GO:0050786)
0.3 5.0 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.3 1.8 GO:0015288 porin activity(GO:0015288)
0.3 1.3 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.3 2.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.3 2.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.2 1.0 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 1.0 GO:0048408 epidermal growth factor binding(GO:0048408)
0.2 1.9 GO:0048495 Roundabout binding(GO:0048495)
0.2 2.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.2 5.1 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.2 3.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2 0.9 GO:0051425 PTB domain binding(GO:0051425)
0.2 5.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 7.2 GO:0001223 transcription coactivator binding(GO:0001223)
0.2 1.3 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.2 4.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 0.9 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.2 2.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 2.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 0.4 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.2 1.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.2 1.6 GO:0015929 hexosaminidase activity(GO:0015929)
0.2 0.8 GO:0070573 tripeptidyl-peptidase activity(GO:0008240) metallodipeptidase activity(GO:0070573)
0.2 0.6 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.2 0.8 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.2 1.2 GO:0009374 biotin binding(GO:0009374)
0.2 7.0 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.2 7.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 6.7 GO:0042805 actinin binding(GO:0042805)
0.2 1.0 GO:0071532 ankyrin repeat binding(GO:0071532)
0.2 2.1 GO:0008430 selenium binding(GO:0008430)
0.2 2.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 1.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 0.2 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.2 0.7 GO:2001069 glycogen binding(GO:2001069)
0.2 1.1 GO:0070728 leucine binding(GO:0070728)
0.2 0.4 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.2 1.4 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.2 0.7 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.2 16.7 GO:0005178 integrin binding(GO:0005178)
0.2 1.8 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.2 5.6 GO:0019838 growth factor binding(GO:0019838)
0.2 5.0 GO:0005112 Notch binding(GO:0005112)
0.2 2.4 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.2 0.3 GO:0019002 GMP binding(GO:0019002)
0.2 1.0 GO:0051525 NFAT protein binding(GO:0051525)
0.2 1.4 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.2 1.8 GO:0030957 Tat protein binding(GO:0030957)
0.2 0.8 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.2 1.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 1.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 2.1 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.2 2.1 GO:0005522 profilin binding(GO:0005522)
0.2 0.5 GO:0031896 alpha-1A adrenergic receptor binding(GO:0031691) alpha-1B adrenergic receptor binding(GO:0031692) follicle-stimulating hormone receptor binding(GO:0031762) V2 vasopressin receptor binding(GO:0031896)
0.2 0.6 GO:0008948 oxaloacetate decarboxylase activity(GO:0008948)
0.2 0.5 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.2 1.1 GO:0030274 LIM domain binding(GO:0030274)
0.2 3.4 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.2 0.6 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.2 1.7 GO:0044548 S100 protein binding(GO:0044548)
0.2 0.9 GO:0043426 MRF binding(GO:0043426)
0.2 9.9 GO:0019003 GDP binding(GO:0019003)
0.2 0.6 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 4.4 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.4 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.1 1.6 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.8 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 3.7 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.5 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.1 0.8 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 1.3 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.1 2.1 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 1.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 5.7 GO:0005518 collagen binding(GO:0005518)
0.1 2.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.5 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.3 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.1 1.0 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.8 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224) RNA polymerase II transcription corepressor binding(GO:0001226)
0.1 0.9 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.1 0.9 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 1.9 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 0.7 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 2.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.3 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466) very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.1 1.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 4.6 GO:0017022 myosin binding(GO:0017022)
0.1 2.4 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.3 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.1 0.3 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 0.5 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 0.6 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 1.6 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.4 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 0.5 GO:0000213 tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.1 0.1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 5.8 GO:0005080 protein kinase C binding(GO:0005080)
0.1 0.3 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 0.4 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 1.0 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.6 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.6 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 1.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.5 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.4 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1 0.4 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 5.1 GO:0008201 heparin binding(GO:0008201)
0.1 3.2 GO:0070888 E-box binding(GO:0070888)
0.1 0.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.8 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 1.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 1.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 1.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.3 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.2 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 0.4 GO:0035591 signaling adaptor activity(GO:0035591)
0.1 0.8 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 0.1 GO:0097677 STAT family protein binding(GO:0097677)
0.1 1.0 GO:0042605 peptide antigen binding(GO:0042605)
0.1 1.1 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 0.4 GO:0050815 phosphoserine binding(GO:0050815)
0.1 0.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 8.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 0.5 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.1 0.8 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 0.4 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.4 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.6 GO:0070403 NAD+ binding(GO:0070403)
0.0 1.1 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0050694 galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 4.6 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.3 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.6 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.6 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.1 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.0 0.3 GO:0005042 netrin receptor activity(GO:0005042)
0.0 1.3 GO:0050699 WW domain binding(GO:0050699)
0.0 0.4 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 2.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.7 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 1.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.1 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 1.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.0 1.7 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 1.9 GO:0005179 hormone activity(GO:0005179)
0.0 0.7 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.0 GO:0015925 galactosidase activity(GO:0015925)
0.0 2.0 GO:0000149 SNARE binding(GO:0000149)
0.0 0.6 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.8 GO:0004407 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.0 0.7 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 1.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.5 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.7 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.1 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.5 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0015149 glucose transmembrane transporter activity(GO:0005355) hexose transmembrane transporter activity(GO:0015149)
0.0 0.7 GO:0048029 monosaccharide binding(GO:0048029)
0.0 0.5 GO:0005507 copper ion binding(GO:0005507)
0.0 0.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.9 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.7 GO:0016209 antioxidant activity(GO:0016209)
0.0 0.3 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.4 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.3 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.0 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.9 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.7 GO:0019209 kinase activator activity(GO:0019209)
0.0 0.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.4 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.2 GO:0070034 telomerase RNA binding(GO:0070034)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 12.1 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.6 16.6 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.5 8.8 ST_STAT3_PATHWAY STAT3 Pathway
0.4 3.3 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.4 17.7 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.4 10.9 PID_VEGFR1_PATHWAY VEGFR1 specific signals
0.4 2.6 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.4 2.8 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.3 16.2 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.3 5.3 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.3 7.3 PID_SHP2_PATHWAY SHP2 signaling
0.3 40.0 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.3 7.8 NABA_COLLAGENS Genes encoding collagen proteins
0.2 4.7 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 3.5 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.2 15.6 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.2 4.3 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.2 9.1 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.2 2.0 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.2 1.4 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.2 3.5 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.2 2.6 PID_IL2_1PATHWAY IL2-mediated signaling events
0.2 0.8 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.8 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.1 1.0 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.1 2.3 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.1 15.9 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 0.8 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 3.9 NABA_CORE_MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.1 3.0 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 21.1 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.1 2.4 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 2.9 PID_FGF_PATHWAY FGF signaling pathway
0.1 2.1 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.1 4.5 PID_AP1_PATHWAY AP-1 transcription factor network
0.1 3.2 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.1 6.4 PID_NOTCH_PATHWAY Notch signaling pathway
0.1 0.6 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 1.9 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.1 4.4 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.1 3.8 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.1 4.7 PID_MTOR_4PATHWAY mTOR signaling pathway
0.1 2.1 PID_INSULIN_PATHWAY Insulin Pathway
0.1 0.9 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 1.5 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 1.6 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 1.2 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 0.4 ST_INTEGRIN_SIGNALING_PATHWAY Integrin Signaling Pathway
0.0 0.7 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.8 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.1 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 0.6 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.5 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.0 0.8 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.2 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 0.8 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.9 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 PID_BARD1_PATHWAY BARD1 signaling events
0.0 0.6 PID_ATM_PATHWAY ATM pathway
0.0 0.4 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.5 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.5 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.5 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 0.7 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 0.1 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.0 0.2 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 0.5 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.8 PID_P73PATHWAY p73 transcription factor network
0.0 0.1 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.6 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
1.1 1.1 REACTOME_SIGNALING_BY_NOTCH2 Genes involved in Signaling by NOTCH2
1.0 7.6 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.9 6.6 REACTOME_SIGNALING_BY_NOTCH4 Genes involved in Signaling by NOTCH4
0.6 11.2 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.6 23.9 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.5 13.3 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.4 4.4 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.4 3.5 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.4 2.2 REACTOME_SIGNALING_BY_EGFR_IN_CANCER Genes involved in Signaling by EGFR in Cancer
0.4 6.8 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.4 9.6 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.4 2.3 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.4 5.9 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.4 20.0 REACTOME_AMYLOIDS Genes involved in Amyloids
0.3 6.9 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.3 3.6 REACTOME_FGFR2C_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.3 2.4 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.3 4.6 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.3 3.6 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.3 5.1 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.3 2.6 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.3 6.1 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.2 0.5 REACTOME_PLATELET_AGGREGATION_PLUG_FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.2 4.7 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.2 2.4 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.2 2.2 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.2 2.3 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 11.4 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2 5.2 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 1.5 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 5.6 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.2 3.3 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 11.3 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.2 1.1 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.2 2.8 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 3.5 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2 4.1 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.2 1.0 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 4.7 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 4.9 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 2.0 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 1.5 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.8 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 6.7 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 0.4 REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.1 1.5 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 3.4 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 3.5 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 1.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 5.1 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 0.9 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 1.4 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.1 0.8 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 0.9 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 2.2 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 0.5 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 0.8 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 0.9 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 0.6 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 3.9 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 5.1 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 0.5 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 1.2 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 1.0 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 1.4 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 0.7 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.1 2.7 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.1 2.0 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 1.3 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.1 1.0 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 1.2 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.7 REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 3.1 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 1.5 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 3.5 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.0 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.4 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 2.1 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.8 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.8 REACTOME_KERATAN_SULFATE_BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 1.2 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 1.3 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.7 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.9 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.1 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.6 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.8 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.3 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 0.7 REACTOME_REGULATION_OF_MITOTIC_CELL_CYCLE Genes involved in Regulation of mitotic cell cycle
0.0 0.3 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.5 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.3 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.8 REACTOME_RNA_POL_III_TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.0 0.6 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.3 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.2 REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.3 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease