---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr17_+_34969912	12.783	ENSMUST00000173680.1	Gm20481	predicted gene 20481
chr11_+_61485431	12.594	ENSMUST00000064783.3 ENSMUST00000040522.6	Mfap4	microfibrillar-associated protein 4
chr14_-_118052235	9.557	ENSMUST00000022725.2	Dct	dopachrome tautomerase
chr2_+_32646586	9.044	ENSMUST00000009705.7 ENSMUST00000167841.1	Eng	endoglin
chr3_+_94933041	8.863	ENSMUST00000090839.5	Selenbp1	selenium binding protein 1
chr11_-_77894096	8.521	ENSMUST00000017597.4	Pipox	pipecolic acid oxidase
chr6_+_135362931	8.067	ENSMUST00000032330.9	Emp1	epithelial membrane protein 1
chr13_-_97747373	7.694	ENSMUST00000123535.1	5330416C01Rik	RIKEN cDNA 5330416C01 gene
chr19_-_42752710	7.508	ENSMUST00000076505.3	Pyroxd2	pyridine nucleotide-disulphide oxidoreductase domain 2
chr7_+_45017953	7.376	ENSMUST00000044111.7	Rras	Harvey rat sarcoma oncogene, subgroup R
chr3_-_85746266	7.272	ENSMUST00000118408.1	Fam160a1	family with sequence similarity 160, member A1
chr14_+_31134853	7.190	ENSMUST00000090212.4	Nt5dc2	5'-nucleotidase domain containing 2
chr6_+_17306335	7.187	ENSMUST00000007799.6 ENSMUST00000115456.1 ENSMUST00000115455.2 ENSMUST00000130505.1	Cav1	caveolin 1, caveolae protein
chr2_-_25469742	7.038	ENSMUST00000114259.2 ENSMUST00000015234.6	Ptgds	prostaglandin D2 synthase (brain)
chr1_+_43730593	6.991	ENSMUST00000027217.8	1500015O10Rik	RIKEN cDNA 1500015O10 gene
chr1_-_191183244	6.398	ENSMUST00000027941.8	Atf3	activating transcription factor 3
chr2_-_25470031	6.184	ENSMUST00000114251.1	Ptgds	prostaglandin D2 synthase (brain)
chr3_-_10208569	5.988	ENSMUST00000029041.4	Fabp4	fatty acid binding protein 4, adipocyte
chr13_-_97747399	5.902	ENSMUST00000144993.1	5330416C01Rik	RIKEN cDNA 5330416C01 gene
chr2_-_180225812	5.819	ENSMUST00000015791.5	Lama5	laminin, alpha 5
chr1_+_185454803	5.746	ENSMUST00000061093.6	Slc30a10	solute carrier family 30, member 10
chr3_+_94693556	5.601	ENSMUST00000090848.3 ENSMUST00000173981.1 ENSMUST00000173849.1 ENSMUST00000174223.1	Selenbp2	selenium binding protein 2
chr3_-_131272077	5.525	ENSMUST00000029610.8	Hadh	hydroxyacyl-Coenzyme A dehydrogenase
chr6_-_115251839	5.284	ENSMUST00000032462.6	Timp4	tissue inhibitor of metalloproteinase 4
chr6_+_29433248	5.228	ENSMUST00000101617.2 ENSMUST00000065090.5	Flnc	filamin C, gamma
chr6_+_17306415	4.967	ENSMUST00000150901.1	Cav1	caveolin 1, caveolae protein
chr3_-_57294880	4.708	ENSMUST00000171384.1	Tm4sf1	transmembrane 4 superfamily member 1
chr10_+_57784859	4.674	ENSMUST00000020024.5	Fabp7	fatty acid binding protein 7, brain
chr5_+_30013141	4.466	ENSMUST00000026845.7	Il6	interleukin 6
chr4_-_155019399	4.418	ENSMUST00000126098.1 ENSMUST00000176194.1	Plch2	phospholipase C, eta 2
chr7_-_97417730	4.261	ENSMUST00000043077.7	Thrsp	thyroid hormone responsive
chr3_-_107760221	4.082	ENSMUST00000153114.1 ENSMUST00000118593.1 ENSMUST00000120243.1	Csf1	colony stimulating factor 1 (macrophage)
chr11_+_115154139	4.008	ENSMUST00000021076.5	Rab37	RAB37, member of RAS oncogene family
chr14_+_54476100	3.931	ENSMUST00000164766.1 ENSMUST00000164697.1	Rem2	rad and gem related GTP binding protein 2
chr7_-_80403315	3.926	ENSMUST00000147150.1	Furin	furin (paired basic amino acid cleaving enzyme)
chr2_+_76650264	3.909	ENSMUST00000099986.2	Dfnb59	deafness, autosomal recessive 59 (human)
chrX_-_48034842	3.836	ENSMUST00000039026.7	Apln	apelin
chr4_+_41762309	3.644	ENSMUST00000108042.2	Il11ra1	interleukin 11 receptor, alpha chain 1
chr6_+_29433131	3.570	ENSMUST00000090474.4	Flnc	filamin C, gamma
chr8_+_94977101	3.553	ENSMUST00000179619.1	Gpr56	G protein-coupled receptor 56
chr11_+_78324200	3.431	ENSMUST00000102478.3	Aldoc	aldolase C, fructose-bisphosphate
chr5_+_135887905	3.424	ENSMUST00000005077.6	Hspb1	heat shock protein 1
chr5_-_134747241	3.325	ENSMUST00000015138.9	Eln	elastin
chr10_-_105574435	3.319	ENSMUST00000061506.8	Tmtc2	transmembrane and tetratricopeptide repeat containing 2
chr9_+_44134562	3.291	ENSMUST00000034650.8 ENSMUST00000098852.2	Mcam	melanoma cell adhesion molecule
chr7_+_27607748	3.263	ENSMUST00000136962.1	Akt2	thymoma viral proto-oncogene 2
chr7_+_27607997	3.225	ENSMUST00000142365.1	Akt2	thymoma viral proto-oncogene 2
chr4_+_137468767	3.150	ENSMUST00000030547.8 ENSMUST00000171332.1	Hspg2	perlecan (heparan sulfate proteoglycan 2)
chr7_+_130936172	3.119	ENSMUST00000006367.7	Htra1	HtrA serine peptidase 1
chr2_+_153065988	3.105	ENSMUST00000129377.1 ENSMUST00000109800.1	Ccm2l	cerebral cavernous malformation 2-like
chr7_-_79386943	2.980	ENSMUST00000053718.8 ENSMUST00000179243.1	Rlbp1	retinaldehyde binding protein 1
chr10_+_57784914	2.955	ENSMUST00000165013.1	Fabp7	fatty acid binding protein 7, brain
chr7_-_19770509	2.884	ENSMUST00000003061.7	Bcam	basal cell adhesion molecule
chr3_-_151749877	2.853	ENSMUST00000029671.7	Ifi44	interferon-induced protein 44
chr15_+_102102926	2.744	ENSMUST00000169627.1 ENSMUST00000046144.9	Tenc1	tensin like C1 domain-containing phosphatase
chr7_-_118995211	2.742	ENSMUST00000008878.8	Gprc5b	G protein-coupled receptor, family C, group 5, member B
chr5_+_137745967	2.689	ENSMUST00000100539.3	Tsc22d4	TSC22 domain family, member 4
chr14_+_62332068	2.675	ENSMUST00000022499.6	Rnaseh2b	ribonuclease H2, subunit B
chr4_+_133584355	2.673	ENSMUST00000030661.7	Gpn2	GPN-loop GTPase 2
chr19_+_6084983	2.669	ENSMUST00000025704.2	Cdca5	cell division cycle associated 5
chr7_+_27447978	2.665	ENSMUST00000037399.9 ENSMUST00000108358.1	Blvrb	biliverdin reductase B (flavin reductase (NADPH))
chr3_-_8667033	2.640	ENSMUST00000042412.3	Hey1	hairy/enhancer-of-split related with YRPW motif 1
chr1_-_162859919	2.567	ENSMUST00000134098.1 ENSMUST00000111518.1	Fmo1	flavin containing monooxygenase 1
chr5_+_137745730	2.556	ENSMUST00000100540.3	Tsc22d4	TSC22 domain family, member 4
chr2_+_164832862	2.524	ENSMUST00000103093.3 ENSMUST00000017904.2	Ctsa	cathepsin A
chr3_-_116129615	2.523	ENSMUST00000029574.8	Vcam1	vascular cell adhesion molecule 1
chr15_-_103366763	2.507	ENSMUST00000023128.6	Itga5	integrin alpha 5 (fibronectin receptor alpha)
chr4_+_133584419	2.499	ENSMUST00000105899.1	Gpn2	GPN-loop GTPase 2
chr5_+_137758133	2.499	ENSMUST00000141733.1 ENSMUST00000110985.1	Tsc22d4	TSC22 domain family, member 4
chr6_+_138141569	2.459	ENSMUST00000118091.1	Mgst1	microsomal glutathione S-transferase 1
chr7_-_105482197	2.451	ENSMUST00000047040.2	Prkcdbp	protein kinase C, delta binding protein
chr2_+_164832881	2.388	ENSMUST00000103092.1 ENSMUST00000151493.1 ENSMUST00000127650.1	Ctsa	cathepsin A
chr2_+_85136355	2.370	ENSMUST00000057019.7	Aplnr	apelin receptor
chr2_-_93849679	2.320	ENSMUST00000068513.4 ENSMUST00000041593.8 ENSMUST00000130077.1	Accs	1-aminocyclopropane-1-carboxylate synthase (non-functional)
chr4_+_94739276	2.307	ENSMUST00000073939.6 ENSMUST00000102798.1	Tek	endothelial-specific receptor tyrosine kinase
chr1_-_90843916	2.305	ENSMUST00000130846.2 ENSMUST00000097653.4 ENSMUST00000056925.9	Col6a3	collagen, type VI, alpha 3
chr9_+_69453620	2.302	ENSMUST00000034756.8 ENSMUST00000123470.1	Anxa2	annexin A2
chr9_+_69454066	2.291	ENSMUST00000134907.1	Anxa2	annexin A2
chr3_-_63851251	2.284	ENSMUST00000162269.2 ENSMUST00000159676.2 ENSMUST00000175947.1	Plch1	phospholipase C, eta 1
chr5_+_64812336	2.279	ENSMUST00000166409.1	Klf3	Kruppel-like factor 3 (basic)
chr14_+_54259227	2.274	ENSMUST00000041197.7	Abhd4	abhydrolase domain containing 4
chr9_-_79718631	2.266	ENSMUST00000180083.1	Col12a1	collagen, type XII, alpha 1
chr11_-_116110211	2.252	ENSMUST00000106441.1 ENSMUST00000021120.5	Trim47	tripartite motif-containing 47
chr11_-_102897123	2.220	ENSMUST00000067444.3	Gfap	glial fibrillary acidic protein
chr1_+_172341197	2.219	ENSMUST00000056136.3	Kcnj10	potassium inwardly-rectifying channel, subfamily J, member 10
chr14_+_31217850	2.208	ENSMUST00000090180.2	Sema3g	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
chr11_-_78984831	2.191	ENSMUST00000073001.4 ENSMUST00000108269.3	Lgals9	lectin, galactose binding, soluble 9
chr1_+_51289106	2.174	ENSMUST00000051572.6	Sdpr	serum deprivation response
chr7_+_47050628	2.159	ENSMUST00000010451.5	Tmem86a	transmembrane protein 86A
chr10_-_19011948	2.142	ENSMUST00000105527.1	Tnfaip3	tumor necrosis factor, alpha-induced protein 3
chr4_-_45532470	2.129	ENSMUST00000147448.1	Shb	src homology 2 domain-containing transforming protein B
chr9_-_106887000	2.119	ENSMUST00000055843.7	Rbm15b	RNA binding motif protein 15B
chr2_-_118762607	2.080	ENSMUST00000059997.8	A430105I19Rik	RIKEN cDNA A430105I19 gene
chr1_-_88277470	2.068	ENSMUST00000147393.1	Hjurp	Holliday junction recognition protein
chr16_+_34784917	2.040	ENSMUST00000023538.8	Mylk	myosin, light polypeptide kinase
chr9_-_79718518	2.027	ENSMUST00000071750.6	Col12a1	collagen, type XII, alpha 1
chr5_+_52582320	1.999	ENSMUST00000177881.1	Gm5866	predicted gene 5866
chr1_-_120120138	1.994	ENSMUST00000112648.1 ENSMUST00000128408.1	Dbi	diazepam binding inhibitor
chr15_-_80014808	1.992	ENSMUST00000000500.6	Pdgfb	platelet derived growth factor, B polypeptide
chr1_-_88277510	1.976	ENSMUST00000065420.5 ENSMUST00000054674.8	Hjurp	Holliday junction recognition protein
chr1_+_92910758	1.975	ENSMUST00000027487.8	Rnpepl1	arginyl aminopeptidase (aminopeptidase B)-like 1
chr3_-_107931579	1.973	ENSMUST00000133947.2 ENSMUST00000124215.1 ENSMUST00000106688.1 ENSMUST00000106687.2	Gstm7	glutathione S-transferase, mu 7
chr16_+_90831113	1.971	ENSMUST00000037539.7 ENSMUST00000099543.3	Eva1c	eva-1 homolog C (C. elegans)
chr9_+_44773191	1.970	ENSMUST00000147559.1	Ift46	intraflagellar transport 46
chr4_-_63403330	1.969	ENSMUST00000035724.4	Akna	AT-hook transcription factor
chr5_+_135725713	1.948	ENSMUST00000127096.1	Por	P450 (cytochrome) oxidoreductase
chr9_-_79718720	1.940	ENSMUST00000121227.1	Col12a1	collagen, type XII, alpha 1
chr13_-_115101909	1.885	ENSMUST00000061673.7	Itga1	integrin alpha 1
chr12_-_112673944	1.870	ENSMUST00000130342.1	Akt1	thymoma viral proto-oncogene 1
chr2_+_30078584	1.857	ENSMUST00000045246.7	Pkn3	protein kinase N3
chr2_+_38339258	1.785	ENSMUST00000143783.2	Lhx2	LIM homeobox protein 2
chr6_-_48841098	1.778	ENSMUST00000101429.4	Tmem176b	transmembrane protein 176B
chr11_-_78984946	1.772	ENSMUST00000108268.3	Lgals9	lectin, galactose binding, soluble 9
chr2_-_181581996	1.742	ENSMUST00000057816.8	Uckl1	uridine-cytidine kinase 1-like 1
chr17_+_28272191	1.741	ENSMUST00000169040.1	Ppard	peroxisome proliferator activator receptor delta
chr2_+_31470207	1.739	ENSMUST00000102840.4	Ass1	argininosuccinate synthetase 1
chr8_-_111910171	1.701	ENSMUST00000034430.4	Chst5	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
chr12_-_31950535	1.696	ENSMUST00000172314.2	Hbp1	high mobility group box transcription factor 1
chr9_-_119977250	1.693	ENSMUST00000035101.7	Csrnp1	cysteine-serine-rich nuclear protein 1
chr4_-_45530330	1.675	ENSMUST00000061986.5	Shb	src homology 2 domain-containing transforming protein B
chr13_-_34994103	1.649	ENSMUST00000171258.1 ENSMUST00000170989.1 ENSMUST00000021854.6 ENSMUST00000110251.2 ENSMUST00000167036.1 ENSMUST00000171229.1 ENSMUST00000178421.1	Eci2	enoyl-Coenzyme A delta isomerase 2
chr7_-_142578139	1.618	ENSMUST00000136359.1	H19	H19 fetal liver mRNA
chr14_+_62292475	1.610	ENSMUST00000166879.1	Rnaseh2b	ribonuclease H2, subunit B
chr6_-_48840988	1.605	ENSMUST00000164733.1	Tmem176b	transmembrane protein 176B
chr7_-_142578093	1.600	ENSMUST00000149974.1 ENSMUST00000152754.1	H19	H19 fetal liver mRNA
chr3_+_94342092	1.570	ENSMUST00000029794.5	Them5	thioesterase superfamily member 5
chr17_+_34203527	1.568	ENSMUST00000025197.5	Tap2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr11_+_62648656	1.556	ENSMUST00000062860.4	Mmgt2	membrane magnesium transporter 2
chr11_+_109485606	1.535	ENSMUST00000106697.1	Arsg	arylsulfatase G
chr9_-_106199253	1.533	ENSMUST00000140761.1	Ppm1m	protein phosphatase 1M
chr3_-_107931817	1.531	ENSMUST00000004137.4	Gstm7	glutathione S-transferase, mu 7
chr3_+_107896247	1.526	ENSMUST00000169365.1	Gstm5	glutathione S-transferase, mu 5
chr9_-_100506844	1.521	ENSMUST00000112874.3	Nck1	non-catalytic region of tyrosine kinase adaptor protein 1
chr10_-_75932468	1.520	ENSMUST00000120281.1 ENSMUST00000000924.6	Mmp11	matrix metallopeptidase 11
chr11_-_94601862	1.518	ENSMUST00000103164.3	Acsf2	acyl-CoA synthetase family member 2
chr7_-_142576492	1.487	ENSMUST00000140716.1	H19	H19 fetal liver mRNA
chr4_+_48045144	1.487	ENSMUST00000030025.3	Nr4a3	nuclear receptor subfamily 4, group A, member 3
chr19_+_24673998	1.486	ENSMUST00000057243.4	Tmem252	transmembrane protein 252
chr11_-_3539228	1.465	ENSMUST00000075118.3 ENSMUST00000136243.1 ENSMUST00000170588.1 ENSMUST00000020721.8	Smtn	smoothelin
chr11_+_99041237	1.456	ENSMUST00000017637.6	Igfbp4	insulin-like growth factor binding protein 4
chr17_-_57247632	1.444	ENSMUST00000005975.6	Gpr108	G protein-coupled receptor 108
chr3_+_88616133	1.424	ENSMUST00000176500.1 ENSMUST00000177498.1	Arhgef2	rho/rac guanine nucleotide exchange factor (GEF) 2
chr6_+_120773633	1.418	ENSMUST00000112682.2	Slc25a18	solute carrier family 25 (mitochondrial carrier), member 18
chr2_+_119167758	1.416	ENSMUST00000057454.3	Gchfr	GTP cyclohydrolase I feedback regulator
chr6_+_83142387	1.388	ENSMUST00000130622.1 ENSMUST00000129316.1	Rtkn	rhotekin
chr11_+_50602072	1.372	ENSMUST00000040523.8	Adamts2	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2
chr9_-_21798502	1.372	ENSMUST00000034717.5	Kank2	KN motif and ankyrin repeat domains 2
chr17_+_28691419	1.355	ENSMUST00000124886.1	Mapk14	mitogen-activated protein kinase 14
chr6_-_83033422	1.337	ENSMUST00000089651.5	Dok1	docking protein 1
chr13_+_74639866	1.332	ENSMUST00000169114.1	Erap1	endoplasmic reticulum aminopeptidase 1
chr2_+_13573927	1.314	ENSMUST00000141365.1 ENSMUST00000028062.2	Vim	vimentin
chr3_-_89393294	1.306	ENSMUST00000142119.1 ENSMUST00000029677.8 ENSMUST00000148361.1	Zbtb7b	zinc finger and BTB domain containing 7B
chr1_-_72874877	1.306	ENSMUST00000027377.8	Igfbp5	insulin-like growth factor binding protein 5
chr8_+_72646728	1.304	ENSMUST00000161254.1	Nwd1	NACHT and WD repeat domain containing 1
chr10_+_81176631	1.302	ENSMUST00000047864.9	Eef2	eukaryotic translation elongation factor 2
chr2_-_167060417	1.288	ENSMUST00000155281.1	Znfx1	zinc finger, NFX1-type containing 1
chr8_+_72646679	1.282	ENSMUST00000161386.1 ENSMUST00000093427.4	Nwd1	NACHT and WD repeat domain containing 1
chr4_-_45489794	1.262	ENSMUST00000146236.1	Shb	src homology 2 domain-containing transforming protein B
chr11_+_62648811	1.260	ENSMUST00000127589.1 ENSMUST00000155759.2	Mmgt2	membrane magnesium transporter 2
chr12_-_112674193	1.258	ENSMUST00000001780.3	Akt1	thymoma viral proto-oncogene 1
chr9_+_44773027	1.251	ENSMUST00000125877.1	Ift46	intraflagellar transport 46
chr14_-_62454793	1.238	ENSMUST00000128573.1	Gucy1b2	guanylate cyclase 1, soluble, beta 2
chr4_-_129227883	1.236	ENSMUST00000106051.1	C77080	expressed sequence C77080
chr12_+_110279228	1.216	ENSMUST00000097228.4	Dio3	deiodinase, iodothyronine type III
chr7_+_80186835	1.216	ENSMUST00000107383.1 ENSMUST00000032754.7	Sema4b	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr17_-_32947372	1.216	ENSMUST00000139353.1	Cyp4f13	cytochrome P450, family 4, subfamily f, polypeptide 13
chr17_+_29319183	1.206	ENSMUST00000114699.1 ENSMUST00000155348.1	Pi16	peptidase inhibitor 16
chr7_-_80232752	1.206	ENSMUST00000065163.8	Cib1	calcium and integrin binding 1 (calmyrin)
chrX_+_166238923	1.199	ENSMUST00000060210.7 ENSMUST00000112233.1	Gpm6b	glycoprotein m6b
chr6_+_43265582	1.194	ENSMUST00000031750.7	Arhgef5	Rho guanine nucleotide exchange factor (GEF) 5
chr7_+_101321703	1.184	ENSMUST00000174291.1 ENSMUST00000167888.2 ENSMUST00000172662.1 ENSMUST00000173270.1 ENSMUST00000174083.1	Stard10	START domain containing 10
chr10_-_77113676	1.180	ENSMUST00000072755.4 ENSMUST00000105409.1	Col18a1	collagen, type XVIII, alpha 1
chr7_+_30553263	1.159	ENSMUST00000044048.7	Hspb6	heat shock protein, alpha-crystallin-related, B6
chr11_+_114851814	1.147	ENSMUST00000053361.5 ENSMUST00000021071.7 ENSMUST00000136785.1	Gprc5c	G protein-coupled receptor, family C, group 5, member C
chr2_-_26604267	1.124	ENSMUST00000028286.5	Agpat2	1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
chr11_+_78322965	1.121	ENSMUST00000017534.8	Aldoc	aldolase C, fructose-bisphosphate
chr17_+_29318850	1.116	ENSMUST00000114701.2	Pi16	peptidase inhibitor 16
chr2_+_106693185	1.111	ENSMUST00000111063.1	Mpped2	metallophosphoesterase domain containing 2
chr9_-_119339989	1.107	ENSMUST00000035092.6	Myd88	myeloid differentiation primary response gene 88
chr1_+_92906959	1.104	ENSMUST00000060913.6	Dusp28	dual specificity phosphatase 28
chr14_+_79481164	1.102	ENSMUST00000040131.5	Elf1	E74-like factor 1
chr3_+_52268337	1.096	ENSMUST00000053764.5	Foxo1	forkhead box O1
chr8_-_64205970	1.091	ENSMUST00000066166.4	Tll1	tolloid-like
chr19_+_32619997	1.084	ENSMUST00000025833.6	Papss2	3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr1_-_172027269	1.083	ENSMUST00000027837.6 ENSMUST00000111264.1	Vangl2	vang-like 2 (van gogh, Drosophila)
chr3_-_90243073	1.081	ENSMUST00000107369.1	Creb3l4	cAMP responsive element binding protein 3-like 4
chr7_-_28598140	1.078	ENSMUST00000108283.1 ENSMUST00000040531.8	Pak4 Samd4b	p21 protein (Cdc42/Rac)-activated kinase 4 sterile alpha motif domain containing 4B
chr4_-_123750236	1.075	ENSMUST00000102636.3	Akirin1	akirin 1
chr1_-_172027251	1.068	ENSMUST00000138714.1	Vangl2	vang-like 2 (van gogh, Drosophila)
chr4_+_139622842	1.063	ENSMUST00000039818.9	Aldh4a1	aldehyde dehydrogenase 4 family, member A1
chr12_-_108275409	1.062	ENSMUST00000136175.1	Ccdc85c	coiled-coil domain containing 85C
chr4_-_91371946	1.055	ENSMUST00000176362.1	Elavl2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr2_-_155945282	1.050	ENSMUST00000040162.2	Gdf5	growth differentiation factor 5
chr5_-_24581879	1.049	ENSMUST00000088299.4	Gm10221	predicted gene 10221
chr3_+_121426495	1.043	ENSMUST00000029773.8	Cnn3	calponin 3, acidic
chr5_-_125058367	1.042	ENSMUST00000134404.1	Ncor2	nuclear receptor co-repressor 2
chr1_+_172481788	1.041	ENSMUST00000127052.1	Igsf9	immunoglobulin superfamily, member 9
chr11_-_102897146	1.003	ENSMUST00000077902.4	Gfap	glial fibrillary acidic protein
chr9_+_59656368	1.000	ENSMUST00000034834.9 ENSMUST00000163694.2	Pkm	pyruvate kinase, muscle
chr14_-_122451109	1.000	ENSMUST00000081580.2	Gm5089	predicted gene 5089

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.0	9.0	GO:1905072	detection of oxygen(GO:0003032) cardiac jelly development(GO:1905072)
2.8	8.5	GO:0006553	lysine metabolic process(GO:0006553)
2.6	13.2	GO:2000255	negative regulation of male germ cell proliferation(GO:2000255)
2.4	12.2	GO:1903609	negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
1.9	5.7	GO:0071579	regulation of zinc ion transport(GO:0071579)
1.8	12.6	GO:0048251	elastic fiber assembly(GO:0048251)
1.6	9.6	GO:0006570	tyrosine metabolic process(GO:0006570)
1.5	4.5	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
1.4	8.5	GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
1.4	4.1	GO:1904139	microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
1.3	4.0	GO:1902714	negative regulation of interferon-gamma secretion(GO:1902714)
1.3	5.2	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
1.3	5.2	GO:1990022	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
1.3	3.8	GO:1904020	regulation of G-protein coupled receptor internalization(GO:1904020)
1.1	6.5	GO:0097473	cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
1.0	3.1	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
0.9	8.1	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.9	2.7	GO:0071921	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.9	3.5	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.9	7.0	GO:0070314	G1 to G0 transition(GO:0070314)
0.8	7.5	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
0.8	2.4	GO:0002030	inhibitory G-protein coupled receptor phosphorylation(GO:0002030)
0.8	3.1	GO:0060709	glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.7	2.2	GO:0060489	orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.7	2.1	GO:0070428	granuloma formation(GO:0002432) negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070432)
0.7	2.1	GO:2000256	positive regulation of male germ cell proliferation(GO:2000256)
0.7	2.0	GO:0035864	response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.7	4.0	GO:0034080	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.7	2.0	GO:0071351	positive regulation of glomerular filtration(GO:0003104) negative regulation of phosphatidylinositol biosynthetic process(GO:0010512) interleukin-18-mediated signaling pathway(GO:0035655) phenotypic switching(GO:0036166) cellular response to interleukin-18(GO:0071351) metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.7	2.6	GO:2000820	comma-shaped body morphogenesis(GO:0072049) negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.6	2.5	GO:0043415	positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.6	2.5	GO:0006982	response to lipid hydroperoxide(GO:0006982) cellular response to lipid hydroperoxide(GO:0071449)
0.6	1.8	GO:0048014	Tie signaling pathway(GO:0048014)
0.6	6.0	GO:0071285	cellular response to lithium ion(GO:0071285)
0.6	2.3	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.6	3.4	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.6	5.1	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.6	2.2	GO:0051933	amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.6	1.1	GO:2000338	chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.5	1.6	GO:0002489	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489)
0.5	3.1	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
0.5	5.1	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.5	1.5	GO:0002191	cap-dependent translational initiation(GO:0002191)
0.5	2.0	GO:0031999	negative regulation of fatty acid beta-oxidation(GO:0031999)
0.5	1.5	GO:0038095	positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
0.5	1.9	GO:0046210	nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.5	3.4	GO:2001199	negative regulation of dendritic cell differentiation(GO:2001199)
0.5	1.0	GO:0010700	negative regulation of norepinephrine secretion(GO:0010700)
0.5	1.4	GO:1901420	negative regulation of response to alcohol(GO:1901420)
0.4	7.6	GO:0060134	prepulse inhibition(GO:0060134)
0.4	3.9	GO:1901386	negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.4	1.7	GO:0010046	arginine biosynthetic process(GO:0006526) response to mycotoxin(GO:0010046)
0.4	4.7	GO:2000653	regulation of genetic imprinting(GO:2000653)
0.4	2.8	GO:0015675	nickel cation transport(GO:0015675)
0.4	1.2	GO:0002408	myeloid dendritic cell chemotaxis(GO:0002408)
0.4	7.4	GO:0032060	bleb assembly(GO:0032060)
0.4	1.9	GO:0051611	negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.4	1.5	GO:0043973	histone H3-K4 acetylation(GO:0043973)
0.4	1.1	GO:0034035	sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.3	1.7	GO:0008655	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.3	6.2	GO:0014823	response to activity(GO:0014823)
0.3	10.0	GO:0050873	brown fat cell differentiation(GO:0050873)
0.3	2.7	GO:0042167	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.3	0.9	GO:0035811	negative regulation of urine volume(GO:0035811)
0.3	1.5	GO:0070458	detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.3	2.7	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
0.3	0.9	GO:0030070	insulin processing(GO:0030070)
0.3	1.1	GO:0070574	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.3	0.8	GO:0072180	mesenchymal cell proliferation involved in ureteric bud development(GO:0072138) mesonephric duct development(GO:0072177) mesonephric duct morphogenesis(GO:0072180)
0.3	1.3	GO:1900147	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.3	1.0	GO:0072365	regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.3	1.3	GO:2000767	positive regulation of cytoplasmic translation(GO:2000767)
0.3	2.1	GO:0071802	negative regulation of podosome assembly(GO:0071802)
0.3	1.8	GO:0032782	bile acid secretion(GO:0032782)
0.3	2.5	GO:0061032	visceral serous pericardium development(GO:0061032)
0.3	2.5	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.2	3.6	GO:0046697	decidualization(GO:0046697)
0.2	2.5	GO:0009404	toxin metabolic process(GO:0009404)
0.2	0.7	GO:0019074	viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.2	1.1	GO:0071455	response to hyperoxia(GO:0055093) cellular response to hyperoxia(GO:0071455)
0.2	1.3	GO:2001185	regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.2	1.3	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.2	1.0	GO:0060591	chondroblast differentiation(GO:0060591)
0.2	2.0	GO:0006691	leukotriene metabolic process(GO:0006691)
0.2	0.4	GO:0010751	negative regulation of nitric oxide mediated signal transduction(GO:0010751) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)
0.2	0.4	GO:0060620	regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.2	4.3	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
0.2	0.6	GO:2000435	regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.2	5.7	GO:0060445	branching involved in salivary gland morphogenesis(GO:0060445)
0.2	1.7	GO:0010745	negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.2	2.9	GO:0030574	collagen catabolic process(GO:0030574)
0.2	1.8	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
0.2	1.2	GO:0015862	uridine transport(GO:0015862)
0.2	0.5	GO:0070488	neutrophil aggregation(GO:0070488)
0.2	1.2	GO:0046549	phenol-containing compound catabolic process(GO:0019336) retinal cone cell development(GO:0046549)
0.2	1.0	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.2	1.3	GO:0019885	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.2	2.3	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.2	1.0	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.2	0.8	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.2	3.4	GO:0010866	regulation of triglyceride biosynthetic process(GO:0010866)
0.2	0.5	GO:0045004	DNA replication proofreading(GO:0045004)
0.2	8.2	GO:0060325	face morphogenesis(GO:0060325)
0.2	1.6	GO:0035336	long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.2	9.2	GO:0048747	muscle fiber development(GO:0048747)
0.2	1.1	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.2	0.6	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.1	3.2	GO:0001539	cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.1	1.3	GO:0046085	adenosine metabolic process(GO:0046085)
0.1	0.9	GO:1902998	macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1	1.8	GO:0045199	maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1	1.1	GO:1990845	adaptive thermogenesis(GO:1990845)
0.1	0.8	GO:0070294	renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.1	0.6	GO:0021562	vestibulocochlear nerve development(GO:0021562)
0.1	0.5	GO:0033580	protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.1	1.1	GO:0006560	proline metabolic process(GO:0006560)
0.1	0.6	GO:0021891	olfactory bulb interneuron development(GO:0021891)
0.1	4.4	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.1	3.2	GO:0060351	cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.1	0.4	GO:0065001	negative regulation of histone H3-K36 methylation(GO:0000415) specification of axis polarity(GO:0065001)
0.1	0.2	GO:0006566	threonine metabolic process(GO:0006566)
0.1	0.5	GO:0034162	toll-like receptor 9 signaling pathway(GO:0034162)
0.1	0.6	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.1	1.0	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1	1.9	GO:0042311	vasodilation(GO:0042311)
0.1	1.1	GO:0050995	negative regulation of lipid catabolic process(GO:0050995)
0.1	0.4	GO:0048793	pronephros development(GO:0048793)
0.1	0.6	GO:0006452	translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1	3.4	GO:0050919	negative chemotaxis(GO:0050919)
0.1	0.3	GO:0071918	urea transmembrane transport(GO:0071918)
0.1	0.5	GO:2000664	positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.1	1.0	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.1	1.1	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.1	0.7	GO:0002536	respiratory burst involved in inflammatory response(GO:0002536) respiratory burst involved in defense response(GO:0002679) negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1	1.7	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.1	0.3	GO:1900110	single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692) negative regulation of histone H3-K9 dimethylation(GO:1900110)
0.1	0.3	GO:2000319	negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.1	3.3	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1	0.8	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.1	1.1	GO:0050860	negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1	0.4	GO:0097475	motor neuron migration(GO:0097475)
0.1	0.3	GO:0000957	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1	0.8	GO:0031639	plasminogen activation(GO:0031639)
0.1	0.6	GO:0033689	negative regulation of osteoblast proliferation(GO:0033689)
0.1	0.3	GO:1902340	telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.1	0.7	GO:0042118	endothelial cell activation(GO:0042118)
0.1	0.1	GO:1900369	negative regulation of RNA interference(GO:1900369)
0.1	1.0	GO:0019884	antigen processing and presentation of exogenous antigen(GO:0019884)
0.1	0.1	GO:0060056	mammary gland involution(GO:0060056)
0.1	1.0	GO:0000338	protein deneddylation(GO:0000338)
0.1	0.5	GO:0035428	hexose transmembrane transport(GO:0035428)
0.1	0.4	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1	0.6	GO:2000773	negative regulation of cellular senescence(GO:2000773)
0.1	0.1	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
0.1	0.2	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.0	1.2	GO:0006182	cGMP biosynthetic process(GO:0006182)
0.0	0.6	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0	0.6	GO:0014887	muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0	0.1	GO:0014063	negative regulation of serotonin secretion(GO:0014063)
0.0	0.5	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	1.3	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
0.0	2.1	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	1.2	GO:0010667	negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0	0.8	GO:0060561	apoptotic process involved in morphogenesis(GO:0060561)
0.0	0.2	GO:0001887	selenium compound metabolic process(GO:0001887) selenocysteine metabolic process(GO:0016259)
0.0	0.3	GO:0036506	maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0	0.1	GO:1903966	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0	3.0	GO:0007601	visual perception(GO:0007601)
0.0	0.9	GO:0031954	positive regulation of protein autophosphorylation(GO:0031954)
0.0	0.9	GO:0035518	histone H2A monoubiquitination(GO:0035518)
0.0	0.3	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.0	0.4	GO:2000035	regulation of stem cell division(GO:2000035)
0.0	0.9	GO:0090200	positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0	0.7	GO:0061036	positive regulation of cartilage development(GO:0061036)
0.0	0.8	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.0	0.2	GO:0002755	MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0	0.4	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0	0.3	GO:0010825	positive regulation of centrosome duplication(GO:0010825)
0.0	0.3	GO:0006206	pyrimidine nucleobase metabolic process(GO:0006206)
0.0	6.7	GO:0016042	lipid catabolic process(GO:0016042)
0.0	0.9	GO:0045214	sarcomere organization(GO:0045214)
0.0	0.3	GO:0019368	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	3.3	GO:0007519	skeletal muscle tissue development(GO:0007519)
0.0	1.2	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.2	GO:1905146	lysosomal protein catabolic process(GO:1905146)
0.0	0.3	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.0	0.1	GO:0002739	regulation of cytokine secretion involved in immune response(GO:0002739)
0.0	0.4	GO:0032211	negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0	0.9	GO:0046329	negative regulation of JNK cascade(GO:0046329)
0.0	1.2	GO:0051438	regulation of ubiquitin-protein transferase activity(GO:0051438)
0.0	0.2	GO:0046415	urate metabolic process(GO:0046415)
0.0	0.6	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.9	GO:0051607	defense response to virus(GO:0051607)
0.0	0.5	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0	0.3	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0	1.1	GO:0030968	endoplasmic reticulum unfolded protein response(GO:0030968)
0.0	0.1	GO:0051409	response to nitrosative stress(GO:0051409)
0.0	0.5	GO:0097178	ruffle assembly(GO:0097178)
0.0	0.7	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0	0.4	GO:0043171	peptide catabolic process(GO:0043171)
0.0	5.3	GO:0016311	dephosphorylation(GO:0016311)
0.0	0.1	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.0	1.4	GO:0010906	regulation of glucose metabolic process(GO:0010906)
0.0	0.5	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.0	0.6	GO:0045669	positive regulation of osteoblast differentiation(GO:0045669)
0.0	2.0	GO:1990830	response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0	0.1	GO:0044130	negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.0	0.1	GO:2000251	positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0	0.1	GO:0045218	zonula adherens maintenance(GO:0045218)
0.0	0.6	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.8	GO:1901800	positive regulation of proteasomal protein catabolic process(GO:1901800)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.3	15.9	GO:0071953	elastic fiber(GO:0071953)
2.1	6.2	GO:0030934	collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
1.5	4.6	GO:1990667	PCSK9-AnxA2 complex(GO:1990667)
1.5	4.5	GO:0005896	interleukin-6 receptor complex(GO:0005896)
1.5	5.8	GO:0043259	laminin-10 complex(GO:0043259)
1.4	4.1	GO:1990682	CSF1-CSF1R complex(GO:1990682)
0.9	12.2	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.8	3.2	GO:0097450	astrocyte end-foot(GO:0097450)
0.7	4.3	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.5	2.2	GO:0060187	cell pole(GO:0060187)
0.5	3.1	GO:0097512	cardiac myofibril(GO:0097512)
0.5	6.5	GO:0032593	insulin-responsive compartment(GO:0032593)
0.5	7.9	GO:0031045	dense core granule(GO:0031045)
0.4	11.0	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.4	2.7	GO:0008278	cohesin complex(GO:0008278)
0.3	1.3	GO:0045098	type III intermediate filament(GO:0045098)
0.3	1.3	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
0.3	0.9	GO:0005927	muscle tendon junction(GO:0005927)
0.2	3.9	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.2	1.6	GO:0042825	TAP complex(GO:0042825)
0.2	4.4	GO:0008305	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.2	2.8	GO:0072546	ER membrane protein complex(GO:0072546)
0.2	3.2	GO:0005605	basal lamina(GO:0005605)
0.2	0.6	GO:0008537	proteasome activator complex(GO:0008537)
0.1	1.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.1	0.5	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.1	2.1	GO:0032433	filopodium tip(GO:0032433)
0.1	4.0	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.1	0.9	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.1	0.7	GO:0071986	Ragulator complex(GO:0071986)
0.1	10.5	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.1	1.5	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.1	2.2	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.1	2.6	GO:0005682	U5 snRNP(GO:0005682)
0.1	9.4	GO:0072562	blood microparticle(GO:0072562)
0.1	1.5	GO:0035686	sperm fibrous sheath(GO:0035686)
0.1	3.2	GO:0030992	intraciliary transport particle B(GO:0030992)
0.1	0.7	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.1	0.5	GO:0008622	epsilon DNA polymerase complex(GO:0008622)
0.1	1.2	GO:0031462	Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1	1.3	GO:0042788	polysomal ribosome(GO:0042788)
0.1	8.0	GO:0016528	sarcoplasm(GO:0016528)
0.1	4.4	GO:0030667	secretory granule membrane(GO:0030667)
0.1	0.5	GO:0060293	P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1	4.7	GO:0005844	polysome(GO:0005844)
0.1	0.5	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.1	1.0	GO:0044232	organelle membrane contact site(GO:0044232)
0.1	1.0	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.1	0.4	GO:0070847	core mediator complex(GO:0070847)
0.1	1.6	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1	0.6	GO:0005642	annulate lamellae(GO:0005642)
0.1	11.4	GO:0001650	fibrillar center(GO:0001650)
0.1	0.6	GO:0000813	ESCRT I complex(GO:0000813)
0.1	10.7	GO:0005777	peroxisome(GO:0005777) microbody(GO:0042579)
0.1	0.8	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1	2.0	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.1	2.0	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.1	2.3	GO:0009925	basal plasma membrane(GO:0009925)
0.1	0.5	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.1	2.1	GO:0002102	podosome(GO:0002102)
0.1	0.6	GO:1990909	Wnt signalosome(GO:1990909)
0.1	3.3	GO:0005581	collagen trimer(GO:0005581)
0.0	0.4	GO:0000783	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0	0.3	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.1	GO:0017109	glutamate-cysteine ligase complex(GO:0017109)
0.0	0.2	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.3	GO:0000502	proteasome complex(GO:0000502)
0.0	2.0	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	7.1	GO:0043292	contractile fiber(GO:0043292)
0.0	0.7	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	6.5	GO:0016323	basolateral plasma membrane(GO:0016323)
0.0	4.0	GO:0055037	recycling endosome(GO:0055037)
0.0	1.0	GO:0005871	kinesin complex(GO:0005871)
0.0	2.2	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.4	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	1.0	GO:0060077	inhibitory synapse(GO:0060077)
0.0	1.6	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	3.1	GO:0036064	ciliary basal body(GO:0036064)
0.0	1.0	GO:0008180	COP9 signalosome(GO:0008180)
0.0	1.0	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	0.1	GO:0042581	specific granule(GO:0042581)
0.0	0.7	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.1	GO:0044530	supraspliceosomal complex(GO:0044530)
0.0	1.3	GO:0031519	PcG protein complex(GO:0031519)
0.0	8.0	GO:0005764	lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0	0.7	GO:0005776	autophagosome(GO:0005776)
0.0	1.7	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	0.8	GO:0005770	late endosome(GO:0005770)
0.0	2.0	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.4	GO:0030673	axolemma(GO:0030673)
0.0	2.1	GO:0005759	mitochondrial matrix(GO:0005759)
0.0	2.2	GO:0031965	nuclear membrane(GO:0031965)
0.0	2.0	GO:0032993	protein-DNA complex(GO:0032993)
0.0	2.3	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.0	3.8	GO:0000790	nuclear chromatin(GO:0000790)
0.0	0.5	GO:0031985	Golgi cisterna(GO:0031985)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.3	13.2	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
2.4	12.2	GO:0070320	inward rectifier potassium channel inhibitor activity(GO:0070320)
2.1	8.5	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
1.8	9.0	GO:0005534	galactose binding(GO:0005534)
1.4	15.1	GO:0008430	selenium binding(GO:0008430)
1.1	4.6	GO:0004859	phospholipase inhibitor activity(GO:0004859) phospholipase A2 inhibitor activity(GO:0019834)
1.0	5.8	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.9	3.6	GO:0004921	interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.9	2.6	GO:0035939	microsatellite binding(GO:0035939)
0.9	11.2	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.8	4.6	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.7	2.2	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.7	2.7	GO:0004074	biliverdin reductase activity(GO:0004074)
0.7	2.0	GO:0030156	benzodiazepine receptor binding(GO:0030156)
0.7	4.0	GO:0016936	galactoside binding(GO:0016936)
0.6	2.5	GO:0008131	primary amine oxidase activity(GO:0008131)
0.6	5.5	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.6	4.3	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.6	5.9	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.6	1.7	GO:0016501	prostacyclin receptor activity(GO:0016501)
0.5	8.5	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.5	2.5	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.5	3.0	GO:0019841	retinol binding(GO:0019841)
0.5	1.9	GO:0016708	nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
0.5	1.9	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
0.4	2.1	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.4	2.8	GO:0015099	nickel cation transmembrane transporter activity(GO:0015099)
0.4	2.8	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.4	1.6	GO:0015433	peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.4	1.1	GO:0005118	sevenless binding(GO:0005118)
0.4	8.8	GO:0030506	ankyrin binding(GO:0030506)
0.4	14.1	GO:0005504	fatty acid binding(GO:0005504)
0.4	3.9	GO:0048406	nerve growth factor binding(GO:0048406)
0.4	6.7	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.3	1.7	GO:0004849	uridine kinase activity(GO:0004849)
0.3	1.7	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.3	1.0	GO:0004743	pyruvate kinase activity(GO:0004743)
0.3	2.0	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.3	1.3	GO:1990254	keratin filament binding(GO:1990254)
0.3	7.5	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.3	2.1	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
0.3	1.1	GO:0070976	TIR domain binding(GO:0070976)
0.3	3.3	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.3	1.1	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
0.3	1.5	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.2	6.4	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.2	1.4	GO:0051525	NFAT protein binding(GO:0051525)
0.2	3.5	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.2	3.8	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.2	0.5	GO:0070061	fructose binding(GO:0070061)
0.2	0.9	GO:0071532	ankyrin repeat binding(GO:0071532)
0.2	0.5	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.2	1.4	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.2	0.7	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2	1.5	GO:0008420	CTD phosphatase activity(GO:0008420)
0.2	2.2	GO:0038191	neuropilin binding(GO:0038191)
0.2	1.5	GO:0030274	LIM domain binding(GO:0030274)
0.2	0.5	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.2	0.9	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.2	2.1	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1	1.0	GO:0098632	protein binding involved in cell-cell adhesion(GO:0098632)
0.1	0.9	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.1	0.6	GO:0015254	glycerol channel activity(GO:0015254)
0.1	1.9	GO:0008097	5S rRNA binding(GO:0008097)
0.1	6.2	GO:0050840	extracellular matrix binding(GO:0050840)
0.1	1.8	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1	10.7	GO:0005080	protein kinase C binding(GO:0005080)
0.1	1.7	GO:0015643	toxic substance binding(GO:0015643)
0.1	1.0	GO:0036122	BMP binding(GO:0036122)
0.1	0.7	GO:0009374	biotin binding(GO:0009374)
0.1	1.5	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.1	1.9	GO:0004697	protein kinase C activity(GO:0004697)
0.1	1.0	GO:0061133	endopeptidase activator activity(GO:0061133)
0.1	6.7	GO:0019003	GDP binding(GO:0019003)
0.1	1.6	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.1	5.1	GO:0001784	phosphotyrosine binding(GO:0001784)
0.1	1.2	GO:0004383	guanylate cyclase activity(GO:0004383)
0.1	2.0	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.1	0.3	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.1	0.6	GO:0005523	tropomyosin binding(GO:0005523)
0.1	0.3	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	0.7	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1	2.6	GO:0001223	transcription coactivator binding(GO:0001223)
0.1	0.5	GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.1	0.2	GO:0008732	threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1	1.9	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.1	0.7	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1	2.1	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	1.7	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.1	1.4	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171)
0.1	1.0	GO:0017127	cholesterol transporter activity(GO:0017127)
0.1	1.1	GO:0035497	cAMP response element binding(GO:0035497)
0.1	0.3	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1	0.3	GO:0001849	complement component C1q binding(GO:0001849)
0.1	0.2	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.1	1.4	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.1	1.1	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0	2.3	GO:0030170	pyridoxal phosphate binding(GO:0030170)
0.0	1.2	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	1.1	GO:0070566	adenylyltransferase activity(GO:0070566)
0.0	0.8	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	1.0	GO:0004129	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.2	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.0	0.9	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.1	GO:0004357	glutamate-cysteine ligase activity(GO:0004357)
0.0	0.5	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	1.0	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.1	GO:0010698	acetyltransferase activator activity(GO:0010698)
0.0	0.1	GO:0003692	left-handed Z-DNA binding(GO:0003692)
0.0	3.0	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	7.3	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	0.6	GO:0035326	enhancer binding(GO:0035326)
0.0	1.8	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.2	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.6	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.3	GO:0015114	phosphate ion transmembrane transporter activity(GO:0015114)
0.0	0.5	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
0.0	0.9	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.4	GO:0043022	ribosome binding(GO:0043022)
0.0	1.0	GO:0004601	peroxidase activity(GO:0004601)
0.0	0.6	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.1	GO:0032896	palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0	0.2	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.3	GO:0009922	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	0.5	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	0.4	GO:0004576	oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	1.8	GO:0030295	protein kinase activator activity(GO:0030295)
0.0	0.4	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	1.0	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	1.1	GO:0005518	collagen binding(GO:0005518)
0.0	2.3	GO:0002020	protease binding(GO:0002020)
0.0	2.0	GO:0008201	heparin binding(GO:0008201)
0.0	0.3	GO:0001163	RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0	6.3	GO:0005525	GTP binding(GO:0005525)
0.0	0.8	GO:0032934	cholesterol binding(GO:0015485) sterol binding(GO:0032934)
0.0	1.6	GO:0005178	integrin binding(GO:0005178)
0.0	0.3	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	1.5	GO:0051087	chaperone binding(GO:0051087)
0.0	0.5	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.2	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	2.5	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	0.4	GO:0051183	vitamin transporter activity(GO:0051183)
0.0	0.4	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	2.8	GO:0042393	histone binding(GO:0042393)
0.0	5.1	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.2	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	2.7	GO:0001012	RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	5.8	PID_INTEGRIN4_PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.5	17.2	PID_PDGFRA_PATHWAY	PDGFR-alpha signaling pathway
0.4	9.6	SA_TRKA_RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.4	4.1	SA_MMP_CYTOKINE_CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.3	4.5	ST_STAT3_PATHWAY	STAT3 Pathway
0.3	4.4	PID_INTEGRIN_CS_PATHWAY	Integrin family cell surface interactions
0.3	3.3	PID_INTEGRIN2_PATHWAY	Beta2 integrin cell surface interactions
0.3	7.3	NABA_BASEMENT_MEMBRANES	Genes encoding structural components of basement membranes
0.2	6.2	NABA_COLLAGENS	Genes encoding collagen proteins
0.2	6.5	PID_HNF3B_PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.2	12.6	PID_HIF1_TFPATHWAY	HIF-1-alpha transcription factor network
0.2	13.1	PID_AP1_PATHWAY	AP-1 transcription factor network
0.2	6.2	PID_RAS_PATHWAY	Regulation of Ras family activation
0.1	6.0	SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES	Genes related to regulation of the actin cytoskeleton
0.1	6.0	PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.1	2.0	PID_S1P_S1P1_PATHWAY	S1P1 pathway
0.1	13.5	NABA_ECM_GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	11.4	NABA_ECM_AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	2.1	PID_CD40_PATHWAY	CD40/CD40L signaling
0.1	2.6	PID_ANGIOPOIETIN_RECEPTOR_PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.1	2.8	PID_RXR_VDR_PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.1	9.4	NABA_ECM_REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	0.7	PID_AVB3_OPN_PATHWAY	Osteopontin-mediated events
0.1	1.5	ST_GA12_PATHWAY	G alpha 12 Pathway
0.1	2.1	PID_REELIN_PATHWAY	Reelin signaling pathway
0.1	1.6	PID_TOLL_ENDOGENOUS_PATHWAY	Endogenous TLR signaling
0.1	1.3	PID_FCER1_PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.9	PID_TRAIL_PATHWAY	TRAIL signaling pathway
0.0	1.7	PID_HES_HEY_PATHWAY	Notch-mediated HES/HEY network
0.0	0.7	PID_MYC_PATHWAY	C-MYC pathway
0.0	1.3	PID_AURORA_B_PATHWAY	Aurora B signaling
0.0	0.3	PID_ERB_GENOMIC_PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.7	PID_IL4_2PATHWAY	IL4-mediated signaling events
0.0	0.8	PID_PI3KCI_PATHWAY	Class I PI3K signaling events
0.0	1.1	PID_MYC_ACTIV_PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.6	PID_ARF6_TRAFFICKING_PATHWAY	Arf6 trafficking events
0.0	0.7	PID_AR_PATHWAY	Coregulation of Androgen receptor activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	1.8	REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.7	17.2	REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.7	9.6	REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.5	7.4	REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.4	3.9	REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.4	4.5	REACTOME_IL_6_SIGNALING	Genes involved in Interleukin-6 signaling
0.3	8.8	REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.3	5.5	REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.3	1.4	REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP	Genes involved in Destabilization of mRNA by KSRP
0.3	6.4	REACTOME_ACTIVATION_OF_GENES_BY_ATF4	Genes involved in Activation of Genes by ATF4
0.2	3.2	REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.2	11.7	REACTOME_COLLAGEN_FORMATION	Genes involved in Collagen formation
0.2	1.5	REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.2	2.8	REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2	12.7	REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS	Genes involved in Integrin cell surface interactions
0.2	2.9	REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2	4.1	REACTOME_GLUTATHIONE_CONJUGATION	Genes involved in Glutathione conjugation
0.2	1.1	REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	1.1	REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1	5.9	REACTOME_GLYCOLYSIS	Genes involved in Glycolysis
0.1	3.7	REACTOME_GLYCOSPHINGOLIPID_METABOLISM	Genes involved in Glycosphingolipid metabolism
0.1	3.5	REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.1	0.8	REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.1	2.7	REACTOME_METABOLISM_OF_PORPHYRINS	Genes involved in Metabolism of porphyrins
0.1	1.3	REACTOME_PURINE_CATABOLISM	Genes involved in Purine catabolism
0.1	1.2	REACTOME_AMINE_DERIVED_HORMONES	Genes involved in Amine-derived hormones
0.1	1.3	REACTOME_SIGNAL_ATTENUATION	Genes involved in Signal attenuation
0.1	1.4	REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1	0.7	REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1	2.1	REACTOME_NOD1_2_SIGNALING_PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	1.1	REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	3.2	REACTOME_NUCLEAR_SIGNALING_BY_ERBB4	Genes involved in Nuclear signaling by ERBB4
0.1	1.5	REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES	Genes involved in Generation of second messenger molecules
0.1	0.4	REACTOME_ER_PHAGOSOME_PATHWAY	Genes involved in ER-Phagosome pathway
0.1	0.9	REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	0.6	REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.1	3.1	REACTOME_MUSCLE_CONTRACTION	Genes involved in Muscle contraction
0.1	0.6	REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.1	4.0	REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1	1.7	REACTOME_KERATAN_SULFATE_BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.1	0.7	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	Genes involved in Extracellular matrix organization
0.1	0.9	REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1	2.7	REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1	0.6	REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1	4.5	REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	3.2	REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	2.7	REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.6	REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.5	REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	1.4	REACTOME_SYNTHESIS_OF_PA	Genes involved in Synthesis of PA
0.0	0.5	REACTOME_IL1_SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.9	REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.6	REACTOME_ZINC_TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.3	REACTOME_PYRIMIDINE_CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.4	REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	2.1	REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.5	REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0	0.8	REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.1	REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.6	REACTOME_MYOGENESIS	Genes involved in Myogenesis
0.0	1.9	REACTOME_PEPTIDE_CHAIN_ELONGATION	Genes involved in Peptide chain elongation
0.0	1.7	REACTOME_G_ALPHA_I_SIGNALLING_EVENTS	Genes involved in G alpha (i) signalling events
0.0	0.5	REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	1.3	REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.3	REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.3	REACTOME_RNA_POL_I_PROMOTER_OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	1.1	REACTOME_GENERIC_TRANSCRIPTION_PATHWAY	Genes involved in Generic Transcription Pathway

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