Motif ID: Nkx1-1_Nkx1-2

Z-value: 0.580

Transcription factors associated with Nkx1-1_Nkx1-2:

Gene SymbolEntrez IDGene Name
Nkx1-1 ENSMUSG00000029112.5 Nkx1-1
Nkx1-2 ENSMUSG00000048528.7 Nkx1-2






Network of associatons between targets according to the STRING database.



First level regulatory network of Nkx1-1_Nkx1-2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_55782500 4.661 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr6_-_23248264 2.582 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr4_-_14621805 2.470 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr12_-_40037387 2.424 ENSMUST00000146905.1
Arl4a
ADP-ribosylation factor-like 4A
chr13_-_102906046 2.331 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr4_-_141599835 2.256 ENSMUST00000141518.1
ENSMUST00000127455.1
ENSMUST00000105784.1
ENSMUST00000147785.1
Fblim1



filamin binding LIM protein 1



chr5_+_140607334 2.053 ENSMUST00000031555.1
Lfng
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr13_-_102905740 1.633 ENSMUST00000167462.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr16_+_52031549 1.591 ENSMUST00000114471.1
Cblb
Casitas B-lineage lymphoma b
chr4_-_14621494 1.522 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr4_-_14621669 1.480 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr18_+_12741324 1.294 ENSMUST00000115857.2
ENSMUST00000121018.1
ENSMUST00000119108.1
Cabyr


calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)


chr11_+_43682038 1.121 ENSMUST00000094294.4
Pwwp2a
PWWP domain containing 2A
chr7_-_143460989 1.096 ENSMUST00000167912.1
ENSMUST00000037287.6
Cdkn1c

cyclin-dependent kinase inhibitor 1C (P57)

chr14_-_5863663 1.016 ENSMUST00000178594.1
Gm8237
predicted gene 8237
chr3_+_121953213 1.007 ENSMUST00000037958.7
ENSMUST00000128366.1
Arhgap29

Rho GTPase activating protein 29

chr4_+_102570065 0.943 ENSMUST00000097950.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr19_+_5490475 0.823 ENSMUST00000116560.2
Cfl1
cofilin 1, non-muscle
chr11_+_43681998 0.777 ENSMUST00000061070.5
Pwwp2a
PWWP domain containing 2A
chr3_-_89101907 0.775 ENSMUST00000081848.8
Fdps
farnesyl diphosphate synthetase
chr5_+_37185897 0.761 ENSMUST00000094840.3
Gm1043
predicted gene 1043
chr7_-_27195727 0.667 ENSMUST00000163311.2
ENSMUST00000126211.1
Snrpa

small nuclear ribonucleoprotein polypeptide A

chr17_-_63863791 0.647 ENSMUST00000050753.3
A930002H24Rik
RIKEN cDNA A930002H24 gene
chr14_-_6266620 0.645 ENSMUST00000096172.5
Gm3411
predicted gene 3411
chr7_-_44929410 0.639 ENSMUST00000107857.3
ENSMUST00000085399.6
ENSMUST00000167930.1
ENSMUST00000166972.1
Ap2a1



adaptor-related protein complex 2, alpha 1 subunit



chr14_+_4198185 0.592 ENSMUST00000180184.1
Gm2974
predicted gene 2974
chr4_-_119294520 0.579 ENSMUST00000079644.6
Ybx1
Y box protein 1
chr1_+_174501796 0.574 ENSMUST00000030039.7
Fmn2
formin 2
chr19_+_41933464 0.485 ENSMUST00000026154.7
Zdhhc16
zinc finger, DHHC domain containing 16
chr9_-_55919605 0.484 ENSMUST00000037408.8
Scaper
S phase cyclin A-associated protein in the ER
chr19_+_11965817 0.480 ENSMUST00000025590.9
Osbp
oxysterol binding protein
chr11_-_21371143 0.479 ENSMUST00000060895.5
Ugp2
UDP-glucose pyrophosphorylase 2
chr12_+_4769375 0.470 ENSMUST00000178879.1
Pfn4
profilin family, member 4
chr7_-_100964371 0.448 ENSMUST00000060174.4
P2ry6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr5_-_143909782 0.446 ENSMUST00000031613.4
ENSMUST00000100483.2
Aimp2

aminoacyl tRNA synthetase complex-interacting multifunctional protein 2

chr10_+_94575257 0.417 ENSMUST00000121471.1
Tmcc3
transmembrane and coiled coil domains 3
chr11_+_87109221 0.417 ENSMUST00000020794.5
Ska2
spindle and kinetochore associated complex subunit 2
chr10_+_128337761 0.412 ENSMUST00000005826.7
Cs
citrate synthase
chr5_-_118244861 0.410 ENSMUST00000117177.1
ENSMUST00000133372.1
ENSMUST00000154786.1
ENSMUST00000121369.1
Rnft2



ring finger protein, transmembrane 2



chr8_-_3694167 0.407 ENSMUST00000005678.4
Fcer2a
Fc receptor, IgE, low affinity II, alpha polypeptide
chr16_-_16359016 0.405 ENSMUST00000023477.7
ENSMUST00000096229.3
ENSMUST00000115749.1
Dnm1l


dynamin 1-like


chr3_-_90389884 0.397 ENSMUST00000029541.5
Slc27a3
solute carrier family 27 (fatty acid transporter), member 3
chr11_+_121237216 0.379 ENSMUST00000103015.3
Narf
nuclear prelamin A recognition factor
chr12_+_4769278 0.368 ENSMUST00000020967.4
Pfn4
profilin family, member 4
chr5_+_143909964 0.363 ENSMUST00000148011.1
ENSMUST00000110709.3
Pms2

postmeiotic segregation increased 2 (S. cerevisiae)

chr2_-_69712461 0.360 ENSMUST00000102706.3
ENSMUST00000073152.6
Fastkd1

FAST kinase domains 1

chr17_-_57031468 0.360 ENSMUST00000007814.8
Khsrp
KH-type splicing regulatory protein
chr8_+_83972951 0.334 ENSMUST00000005606.6
Prkaca
protein kinase, cAMP dependent, catalytic, alpha
chrX_+_170009892 0.312 ENSMUST00000180251.1
Gm21887
predicted gene, 21887
chrX_+_106015699 0.290 ENSMUST00000033582.4
Cox7b
cytochrome c oxidase subunit VIIb
chr7_+_101896817 0.274 ENSMUST00000143835.1
Anapc15
anaphase prompoting complex C subunit 15
chr11_+_21572221 0.270 ENSMUST00000020568.3
ENSMUST00000131135.1
Wdpcp

WD repeat containing planar cell polarity effector

chr6_+_68161415 0.262 ENSMUST00000168090.1
Igkv1-115
immunoglobulin kappa variable 1-115
chr8_-_86580664 0.261 ENSMUST00000131423.1
ENSMUST00000152438.1
Abcc12

ATP-binding cassette, sub-family C (CFTR/MRP), member 12

chr18_+_4993795 0.253 ENSMUST00000153016.1
Svil
supervillin
chr5_-_34660068 0.242 ENSMUST00000041364.9
Nop14
NOP14 nucleolar protein
chr15_+_81663889 0.222 ENSMUST00000023029.8
ENSMUST00000174229.1
ENSMUST00000172748.1
L3mbtl2


l(3)mbt-like 2 (Drosophila)


chr18_+_24603952 0.215 ENSMUST00000025120.6
Elp2
elongator acetyltransferase complex subunit 2
chr8_+_113635550 0.215 ENSMUST00000179926.1
Mon1b
MON1 homolog b (yeast)
chr2_-_102400257 0.198 ENSMUST00000152929.1
Trim44
tripartite motif-containing 44
chr15_+_75993756 0.195 ENSMUST00000089669.4
Mapk15
mitogen-activated protein kinase 15
chr12_+_52699297 0.191 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr7_+_101896340 0.187 ENSMUST00000035395.7
ENSMUST00000106973.1
ENSMUST00000144207.1
Anapc15


anaphase prompoting complex C subunit 15


chr8_+_40354303 0.185 ENSMUST00000136835.1
Micu3
mitochondrial calcium uptake family, member 3
chr9_-_107872403 0.169 ENSMUST00000183035.1
Rbm6
RNA binding motif protein 6
chr8_+_33599608 0.165 ENSMUST00000009774.9
Ppp2cb
protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform
chr19_+_29367447 0.157 ENSMUST00000016640.7
Cd274
CD274 antigen
chr18_-_24603791 0.155 ENSMUST00000070726.3
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr2_+_151494182 0.151 ENSMUST00000089140.6
Nsfl1c
NSFL1 (p97) cofactor (p47)
chr19_-_29367294 0.143 ENSMUST00000138051.1
Plgrkt
plasminogen receptor, C-terminal lysine transmembrane protein
chr18_-_24603464 0.131 ENSMUST00000154205.1
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr8_-_34965631 0.130 ENSMUST00000033929.4
Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr8_+_113635787 0.130 ENSMUST00000035777.8
Mon1b
MON1 homolog b (yeast)
chr7_+_3645267 0.127 ENSMUST00000038913.9
Cnot3
CCR4-NOT transcription complex, subunit 3
chr4_-_140774196 0.125 ENSMUST00000026381.6
Padi4
peptidyl arginine deiminase, type IV
chr2_-_37703845 0.122 ENSMUST00000155237.1
Strbp
spermatid perinuclear RNA binding protein
chr6_+_37870786 0.120 ENSMUST00000120428.1
ENSMUST00000031859.7
Trim24

tripartite motif-containing 24

chr9_-_20959785 0.106 ENSMUST00000177754.1
Dnmt1
DNA methyltransferase (cytosine-5) 1
chr13_+_75967704 0.105 ENSMUST00000022081.1
Spata9
spermatogenesis associated 9
chrY_+_90784738 0.103 ENSMUST00000179483.1
Erdr1
erythroid differentiation regulator 1
chr12_-_4769217 0.080 ENSMUST00000053458.5
Fam228b
family with sequence similarity 228, member B
chr2_-_45112890 0.079 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chr11_-_20332689 0.067 ENSMUST00000109594.1
Slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr15_+_98092569 0.064 ENSMUST00000163507.1
Pfkm
phosphofructokinase, muscle
chrY_+_90785442 0.064 ENSMUST00000177591.1
ENSMUST00000177671.1
ENSMUST00000179077.1
Erdr1


erythroid differentiation regulator 1


chr19_-_41933276 0.060 ENSMUST00000075280.4
ENSMUST00000112123.2
Exosc1

exosome component 1

chr19_+_8802486 0.055 ENSMUST00000172175.1
Zbtb3
zinc finger and BTB domain containing 3
chr11_-_20332654 0.050 ENSMUST00000004634.6
Slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr7_+_27195781 0.046 ENSMUST00000108379.1
ENSMUST00000179391.1
BC024978

cDNA sequence BC024978

chr9_-_100486788 0.038 ENSMUST00000098458.3
Il20rb
interleukin 20 receptor beta
chr15_+_9436028 0.036 ENSMUST00000042360.3
Capsl
calcyphosine-like
chr5_+_9100681 0.036 ENSMUST00000115365.1
Tmem243
transmembrane protein 243, mitochondrial
chr6_-_124779686 0.024 ENSMUST00000147669.1
ENSMUST00000128697.1
ENSMUST00000032218.3
ENSMUST00000112475.2
Lrrc23



leucine rich repeat containing 23



chr9_+_66126611 0.020 ENSMUST00000034945.5
Fam96a
family with sequence similarity 96, member A
chrX_-_160138375 0.019 ENSMUST00000033662.8
Pdha1
pyruvate dehydrogenase E1 alpha 1
chr2_+_36230426 0.016 ENSMUST00000062069.5
Ptgs1
prostaglandin-endoperoxide synthase 1
chr5_+_115605642 0.014 ENSMUST00000094427.3
Gcn1l1
GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
chr7_-_73537621 0.013 ENSMUST00000172704.1
Chd2
chromodomain helicase DNA binding protein 2
chr7_-_38019505 0.009 ENSMUST00000085513.4
Uri1
URI1, prefoldin-like chaperone
chr10_+_88146992 0.001 ENSMUST00000052355.7
Nup37
nucleoporin 37
chr9_-_54661666 0.001 ENSMUST00000128624.1
Acsbg1
acyl-CoA synthetase bubblegum family member 1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.5 GO:0019532 oxalate transport(GO:0019532)
0.5 1.6 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.4 2.6 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.4 2.1 GO:0007386 compartment pattern specification(GO:0007386)
0.3 0.8 GO:2000812 unidimensional cell growth(GO:0009826) establishment or maintenance of cell polarity regulating cell shape(GO:0071963) regulation of barbed-end actin filament capping(GO:2000812)
0.2 0.4 GO:0030321 transepithelial chloride transport(GO:0030321)
0.2 0.6 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.2 0.6 GO:0070649 meiotic chromosome movement towards spindle pole(GO:0016344) formin-nucleated actin cable assembly(GO:0070649)
0.2 0.5 GO:0006011 UDP-glucose metabolic process(GO:0006011) glucose 1-phosphate metabolic process(GO:0019255)
0.2 2.3 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.4 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
0.1 1.2 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.1 0.4 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.1 0.4 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.1 0.4 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.1 0.6 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.3 GO:0019085 early viral transcription(GO:0019085)
0.1 0.3 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.1 0.8 GO:0016114 terpenoid biosynthetic process(GO:0016114)
0.1 0.8 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 1.3 GO:0048240 sperm capacitation(GO:0048240)
0.1 0.9 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 2.4 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 0.3 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.2 GO:2000481 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.0 0.1 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.0 0.5 GO:0044144 regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144)
0.0 0.1 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.4 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.5 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0015825 L-serine transport(GO:0015825)
0.0 0.4 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.2 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.1 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.0 0.5 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0007398 ectoderm development(GO:0007398)
0.0 4.7 GO:0043010 camera-type eye development(GO:0043010)
0.0 0.1 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
0.0 0.0 GO:0002865 immune response-inhibiting signal transduction(GO:0002765) negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865)
0.0 0.2 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.2 GO:1904355 positive regulation of telomere capping(GO:1904355)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 1.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.4 GO:0032389 MutLalpha complex(GO:0032389)
0.1 0.4 GO:0005638 lamin filament(GO:0005638)
0.1 0.2 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.2 GO:0030689 Noc complex(GO:0030689)
0.0 2.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.6 GO:0032433 filopodium tip(GO:0032433)
0.0 0.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.7 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.6 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 2.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.3 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 5.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.3 GO:0044447 axoneme part(GO:0044447)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.8 GO:0030175 filopodium(GO:0030175)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.5 5.5 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.2 2.3 GO:0031005 filamin binding(GO:0031005)
0.1 0.7 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.8 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 0.4 GO:0019863 IgE binding(GO:0019863)
0.1 0.4 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 0.4 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.1 1.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.4 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.5 GO:0070569 pyrimidine ribonucleotide binding(GO:0032557) uridylyltransferase activity(GO:0070569)
0.0 4.7 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0034618 arginine binding(GO:0034618)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.6 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.4 GO:0051400 BH domain binding(GO:0051400)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.6 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) L-proline transmembrane transporter activity(GO:0015193) alanine transmembrane transporter activity(GO:0022858)
0.0 0.2 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 2.7 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.6 PID_CD40_PATHWAY CD40/CD40L signaling
0.0 0.6 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.3 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.2 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.0 0.1 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.0 0.6 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 2.3 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 5.6 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 0.5 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.4 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 0.8 REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 1.6 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.4 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.8 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.6 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.4 REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.4 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME_PD1_SIGNALING Genes involved in PD-1 signaling
0.0 0.3 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.5 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis