Motif ID: Nkx6-1_Evx1_Hesx1

Z-value: 0.888

Transcription factors associated with Nkx6-1_Evx1_Hesx1:

Gene SymbolEntrez IDGene Name
Evx1 ENSMUSG00000005503.8 Evx1
Hesx1 ENSMUSG00000040726.8 Hesx1
Nkx6-1 ENSMUSG00000035187.8 Nkx6-1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nkx6-1mm10_v2_chr5_-_101665195_1016652260.163.3e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Nkx6-1_Evx1_Hesx1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_+_25773985 9.024 ENSMUST00000125667.1
Myo10
myosin X
chr2_-_79456750 6.146 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chr4_+_8690399 5.802 ENSMUST00000127476.1
Chd7
chromodomain helicase DNA binding protein 7
chr3_-_49757257 5.697 ENSMUST00000035931.7
Pcdh18
protocadherin 18
chrM_+_9870 5.368 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr5_-_84417359 5.319 ENSMUST00000113401.1
Epha5
Eph receptor A5
chrX_+_56454871 5.200 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr1_-_24612700 5.158 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chr9_+_118478182 5.118 ENSMUST00000111763.1
Eomes
eomesodermin homolog (Xenopus laevis)
chrM_+_11734 5.070 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chr5_-_62766153 5.040 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr14_-_118052235 5.017 ENSMUST00000022725.2
Dct
dopachrome tautomerase
chr2_+_20737306 5.007 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr9_+_118478344 4.925 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chrM_+_7759 4.680 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chrM_+_10167 4.605 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr2_+_116067213 4.484 ENSMUST00000152412.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chr1_-_172027269 4.193 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2

vang-like 2 (van gogh, Drosophila)

chr2_-_116067391 4.137 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr13_+_44121167 4.030 ENSMUST00000163056.1
ENSMUST00000159595.1
Gm5083

predicted gene 5083

chr14_-_100149764 3.803 ENSMUST00000097079.4
Klf12
Kruppel-like factor 12
chr1_+_139454747 3.427 ENSMUST00000053364.8
ENSMUST00000097554.3
Aspm

asp (abnormal spindle)-like, microcephaly associated (Drosophila)

chr5_-_53707532 3.402 ENSMUST00000031093.3
Cckar
cholecystokinin A receptor
chr7_+_29071597 3.338 ENSMUST00000180926.1
Gm26604
predicted gene, 26604
chr1_-_172027251 3.159 ENSMUST00000138714.1
Vangl2
vang-like 2 (van gogh, Drosophila)
chr16_+_33684538 2.951 ENSMUST00000126532.1
Heg1
HEG homolog 1 (zebrafish)
chr8_-_61902669 2.923 ENSMUST00000121785.1
ENSMUST00000034057.7
Palld

palladin, cytoskeletal associated protein

chr16_-_63864114 2.819 ENSMUST00000064405.6
Epha3
Eph receptor A3
chr6_-_101377897 2.748 ENSMUST00000075994.6
Pdzrn3
PDZ domain containing RING finger 3
chr13_-_56252163 2.723 ENSMUST00000058475.4
Neurog1
neurogenin 1
chrM_+_7005 2.710 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr10_+_18469958 2.678 ENSMUST00000162891.1
ENSMUST00000100054.3
Nhsl1

NHS-like 1

chrM_+_2743 2.553 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr17_-_35697971 2.491 ENSMUST00000146472.1
Ddr1
discoidin domain receptor family, member 1
chr4_-_155056784 2.485 ENSMUST00000131173.2
Plch2
phospholipase C, eta 2
chr9_+_65890237 2.481 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr17_+_17402672 2.434 ENSMUST00000115576.2
Lix1
limb expression 1 homolog (chicken)
chr7_+_123123870 2.404 ENSMUST00000094053.5
Tnrc6a
trinucleotide repeat containing 6a
chr6_-_57535422 2.400 ENSMUST00000042766.3
Ppm1k
protein phosphatase 1K (PP2C domain containing)
chr3_-_88410295 2.399 ENSMUST00000056370.7
Pmf1
polyamine-modulated factor 1
chr14_+_73237891 2.362 ENSMUST00000044405.6
Lpar6
lysophosphatidic acid receptor 6
chr4_-_109665249 2.325 ENSMUST00000063531.4
Cdkn2c
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr9_+_96258697 2.309 ENSMUST00000179416.1
Tfdp2
transcription factor Dp 2
chr1_-_190170671 2.289 ENSMUST00000175916.1
Prox1
prospero-related homeobox 1
chr2_+_125068118 2.221 ENSMUST00000070353.3
Slc24a5
solute carrier family 24, member 5
chr5_+_138187485 2.171 ENSMUST00000110934.2
Cnpy4
canopy 4 homolog (zebrafish)
chr5_-_99252839 2.160 ENSMUST00000168092.1
ENSMUST00000031276.8
Rasgef1b

RasGEF domain family, member 1B

chr8_+_45627709 2.057 ENSMUST00000134321.1
ENSMUST00000135336.1
Sorbs2

sorbin and SH3 domain containing 2

chr2_+_84734050 2.046 ENSMUST00000090729.2
Ypel4
yippee-like 4 (Drosophila)
chr4_+_109978004 2.009 ENSMUST00000061187.3
Dmrta2
doublesex and mab-3 related transcription factor like family A2
chr2_+_25372315 1.982 ENSMUST00000028329.6
ENSMUST00000114293.2
ENSMUST00000100323.2
Sapcd2


suppressor APC domain containing 2


chr7_-_73541738 1.935 ENSMUST00000169922.2
Chd2
chromodomain helicase DNA binding protein 2
chr15_+_55307743 1.925 ENSMUST00000023053.5
ENSMUST00000110221.2
ENSMUST00000110217.3
Col14a1


collagen, type XIV, alpha 1


chr13_+_44729535 1.874 ENSMUST00000174068.1
Jarid2
jumonji, AT rich interactive domain 2
chr4_+_97777780 1.868 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
Nfia


nuclear factor I/A


chr8_+_23411490 1.848 ENSMUST00000033952.7
Sfrp1
secreted frizzled-related protein 1
chr4_-_45532470 1.842 ENSMUST00000147448.1
Shb
src homology 2 domain-containing transforming protein B
chr12_-_55014329 1.815 ENSMUST00000172875.1
Baz1a
bromodomain adjacent to zinc finger domain 1A
chrM_-_14060 1.788 ENSMUST00000082419.1
mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr7_+_103550368 1.775 ENSMUST00000106888.1
Olfr613
olfactory receptor 613
chr12_-_54986363 1.770 ENSMUST00000173433.1
ENSMUST00000173803.1
Baz1a
Gm20403
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr4_-_97778042 1.731 ENSMUST00000146447.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr2_+_23069210 1.713 ENSMUST00000155602.1
Acbd5
acyl-Coenzyme A binding domain containing 5
chr6_+_34746368 1.701 ENSMUST00000142716.1
Cald1
caldesmon 1
chr12_-_111813834 1.662 ENSMUST00000021715.5
Xrcc3
X-ray repair complementing defective repair in Chinese hamster cells 3
chr5_-_131616599 1.648 ENSMUST00000161804.1
Auts2
autism susceptibility candidate 2
chr16_+_33684460 1.644 ENSMUST00000152782.1
ENSMUST00000179453.1
Heg1

HEG homolog 1 (zebrafish)

chr3_+_76075583 1.623 ENSMUST00000160261.1
Fstl5
follistatin-like 5
chr7_+_67647405 1.596 ENSMUST00000032774.8
ENSMUST00000107471.1
Ttc23

tetratricopeptide repeat domain 23

chrM_+_3906 1.588 ENSMUST00000082396.1
mt-Nd2
mitochondrially encoded NADH dehydrogenase 2
chr1_-_155417394 1.572 ENSMUST00000111775.1
ENSMUST00000111774.1
Xpr1

xenotropic and polytropic retrovirus receptor 1

chr14_-_47411666 1.508 ENSMUST00000111778.3
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr3_+_32436376 1.476 ENSMUST00000108242.1
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr13_-_103764502 1.473 ENSMUST00000074616.5
Srek1
splicing regulatory glutamine/lysine-rich protein 1
chr18_+_57468478 1.441 ENSMUST00000091892.2
Ctxn3
cortexin 3
chr6_+_56017489 1.427 ENSMUST00000052827.4
Ppp1r17
protein phosphatase 1, regulatory subunit 17
chr9_-_96719549 1.425 ENSMUST00000128269.1
Zbtb38
zinc finger and BTB domain containing 38
chr8_+_45658731 1.419 ENSMUST00000143820.1
ENSMUST00000132139.1
Sorbs2

sorbin and SH3 domain containing 2

chr6_+_37870786 1.408 ENSMUST00000120428.1
ENSMUST00000031859.7
Trim24

tripartite motif-containing 24

chr8_+_45658666 1.400 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
Sorbs2


sorbin and SH3 domain containing 2


chr5_+_103754560 1.373 ENSMUST00000153165.1
ENSMUST00000031256.5
Aff1

AF4/FMR2 family, member 1

chr8_-_84662841 1.369 ENSMUST00000060427.4
Ier2
immediate early response 2
chrX_-_74246534 1.359 ENSMUST00000101454.2
ENSMUST00000033699.6
Flna

filamin, alpha

chr9_-_96719404 1.358 ENSMUST00000140121.1
Zbtb38
zinc finger and BTB domain containing 38
chr17_-_29007925 1.345 ENSMUST00000009138.5
ENSMUST00000119274.1
Stk38

serine/threonine kinase 38

chr13_-_85127514 1.328 ENSMUST00000179230.1
Gm4076
predicted gene 4076
chr3_+_32436151 1.326 ENSMUST00000029201.7
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr5_+_64812336 1.310 ENSMUST00000166409.1
Klf3
Kruppel-like factor 3 (basic)
chr17_+_3532554 1.300 ENSMUST00000168560.1
Cldn20
claudin 20
chr7_+_67655414 1.299 ENSMUST00000107470.1
Ttc23
tetratricopeptide repeat domain 23
chrM_+_14138 1.295 ENSMUST00000082421.1
mt-Cytb
mitochondrially encoded cytochrome b
chr14_-_12345847 1.288 ENSMUST00000022262.4
Fezf2
Fez family zinc finger 2
chr4_+_62583568 1.287 ENSMUST00000098031.3
Rgs3
regulator of G-protein signaling 3
chr11_-_87359011 1.282 ENSMUST00000055438.4
Ppm1e
protein phosphatase 1E (PP2C domain containing)
chr10_+_127420867 1.267 ENSMUST00000064793.6
R3hdm2
R3H domain containing 2
chrX_-_102157065 1.253 ENSMUST00000056904.2
Ercc6l
excision repair cross-complementing rodent repair deficiency complementation group 6 like
chr2_+_119047129 1.237 ENSMUST00000153300.1
ENSMUST00000028799.5
Casc5

cancer susceptibility candidate 5

chr2_+_61593077 1.212 ENSMUST00000112495.1
ENSMUST00000112501.2
Tank

TRAF family member-associated Nf-kappa B activator

chr8_-_120228221 1.195 ENSMUST00000183235.1
A330074K22Rik
RIKEN cDNA A330074K22 gene
chr4_-_43499608 1.189 ENSMUST00000136005.1
ENSMUST00000054538.6
Arhgef39

Rho guanine nucleotide exchange factor (GEF) 39

chr17_-_70853482 1.179 ENSMUST00000118283.1
Tgif1
TGFB-induced factor homeobox 1
chr5_+_92809372 1.166 ENSMUST00000113054.2
Shroom3
shroom family member 3
chr10_+_26772477 1.153 ENSMUST00000039557.7
Arhgap18
Rho GTPase activating protein 18
chr9_-_15357692 1.152 ENSMUST00000098979.3
ENSMUST00000161132.1
5830418K08Rik

RIKEN cDNA 5830418K08 gene

chr19_+_23723279 1.142 ENSMUST00000067077.1
Gm9938
predicted gene 9938
chr9_-_66514567 1.127 ENSMUST00000056890.8
Fbxl22
F-box and leucine-rich repeat protein 22
chr3_+_127553462 1.121 ENSMUST00000043108.4
4930422G04Rik
RIKEN cDNA 4930422G04 gene
chr2_+_69897220 1.102 ENSMUST00000055758.9
ENSMUST00000112251.2
Ubr3

ubiquitin protein ligase E3 component n-recognin 3

chr16_+_42907563 1.098 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chr10_-_117148474 1.093 ENSMUST00000020381.3
Frs2
fibroblast growth factor receptor substrate 2
chr4_-_110292719 1.086 ENSMUST00000106601.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr18_+_82914632 1.077 ENSMUST00000071233.6
Zfp516
zinc finger protein 516
chr15_+_25742314 1.069 ENSMUST00000135981.1
Myo10
myosin X
chr2_+_144527718 1.067 ENSMUST00000028914.2
ENSMUST00000110017.2
Polr3f

polymerase (RNA) III (DNA directed) polypeptide F

chr7_-_37772868 1.057 ENSMUST00000176205.1
Zfp536
zinc finger protein 536
chr16_-_26989974 1.053 ENSMUST00000089832.4
Gmnc
geminin coiled-coil domain containing
chr1_-_163725123 1.047 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr14_+_79515618 1.042 ENSMUST00000110835.1
Elf1
E74-like factor 1
chr5_-_124095749 1.041 ENSMUST00000031354.4
Abcb9
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr8_-_26119125 1.039 ENSMUST00000037182.7
Hook3
hook homolog 3 (Drosophila)
chr9_+_72274966 1.035 ENSMUST00000183410.1
Zfp280d
zinc finger protein 280D
chr9_+_52047150 1.033 ENSMUST00000163153.1
Rdx
radixin
chr10_+_58394381 1.022 ENSMUST00000105468.1
Lims1
LIM and senescent cell antigen-like domains 1
chr9_-_50739365 1.021 ENSMUST00000117093.1
ENSMUST00000121634.1
Dixdc1

DIX domain containing 1

chrX_-_60403947 1.015 ENSMUST00000033480.6
ENSMUST00000101527.2
Atp11c

ATPase, class VI, type 11C

chr3_+_94413244 1.012 ENSMUST00000166032.1
ENSMUST00000045245.5
Tdrkh

tudor and KH domain containing protein

chr14_+_12189943 1.010 ENSMUST00000119888.1
Ptprg
protein tyrosine phosphatase, receptor type, G
chr4_-_82850721 0.998 ENSMUST00000139401.1
Zdhhc21
zinc finger, DHHC domain containing 21
chr6_-_54593139 0.997 ENSMUST00000046520.6
Fkbp14
FK506 binding protein 14
chr9_+_13621646 0.996 ENSMUST00000034401.8
Maml2
mastermind like 2 (Drosophila)
chr4_+_80910646 0.988 ENSMUST00000055922.3
Lurap1l
leucine rich adaptor protein 1-like
chr3_-_157925056 0.981 ENSMUST00000118539.1
Cth
cystathionase (cystathionine gamma-lyase)
chr2_+_61593125 0.978 ENSMUST00000112494.1
Tank
TRAF family member-associated Nf-kappa B activator
chrM_+_5319 0.977 ENSMUST00000082402.1
mt-Co1
mitochondrially encoded cytochrome c oxidase I
chr10_+_127421124 0.972 ENSMUST00000170336.1
R3hdm2
R3H domain containing 2
chrX_-_60893430 0.967 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr2_+_52038005 0.956 ENSMUST00000065927.5
Tnfaip6
tumor necrosis factor alpha induced protein 6
chr12_+_72441852 0.952 ENSMUST00000162159.1
Lrrc9
leucine rich repeat containing 9
chr17_+_45734506 0.949 ENSMUST00000180558.1
F630040K05Rik
RIKEN cDNA F630040K05 gene
chr5_-_88675190 0.948 ENSMUST00000133532.1
ENSMUST00000150438.1
Grsf1

G-rich RNA sequence binding factor 1

chr3_-_19264959 0.945 ENSMUST00000121951.1
Pde7a
phosphodiesterase 7A
chr13_+_23575753 0.929 ENSMUST00000105105.1
Hist1h3d
histone cluster 1, H3d
chr4_-_24430838 0.922 ENSMUST00000183964.1
RP23-35K5.2
RP23-35K5.2
chr3_-_123672321 0.914 ENSMUST00000172537.1
ENSMUST00000029602.6
Ndst3

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3

chr12_+_71170589 0.910 ENSMUST00000129376.1
2700049A03Rik
RIKEN cDNA 2700049A03 gene
chr1_-_155417283 0.906 ENSMUST00000027741.5
Xpr1
xenotropic and polytropic retrovirus receptor 1
chr3_-_66296807 0.897 ENSMUST00000029419.7
Veph1
ventricular zone expressed PH domain-containing 1
chrX_+_112604274 0.890 ENSMUST00000071814.6
Zfp711
zinc finger protein 711
chr16_-_16560201 0.883 ENSMUST00000162045.1
ENSMUST00000162124.1
ENSMUST00000161861.1
Fgd4


FYVE, RhoGEF and PH domain containing 4


chr16_-_45724600 0.879 ENSMUST00000096057.4
Tagln3
transgelin 3
chrX_-_53269786 0.876 ENSMUST00000114841.1
ENSMUST00000071023.5
Fam122b

family with sequence similarity 122, member B

chr9_-_106891401 0.875 ENSMUST00000069036.7
Manf
mesencephalic astrocyte-derived neurotrophic factor
chr10_+_58394361 0.874 ENSMUST00000020077.4
Lims1
LIM and senescent cell antigen-like domains 1
chr11_+_23666479 0.871 ENSMUST00000143117.1
Pus10
pseudouridylate synthase 10
chr7_+_64185459 0.861 ENSMUST00000177102.2
ENSMUST00000107519.1
ENSMUST00000137650.1
ENSMUST00000032737.5
ENSMUST00000107515.1
ENSMUST00000144996.1
Trpm1





transient receptor potential cation channel, subfamily M, member 1





chr13_-_62607499 0.859 ENSMUST00000091563.4
6720489N17Rik
RIKEN cDNA 6720489N17 gene
chr6_+_134929118 0.859 ENSMUST00000185152.1
ENSMUST00000184504.1
RP23-45G16.5

RP23-45G16.5

chr4_-_58553553 0.857 ENSMUST00000107575.2
ENSMUST00000107574.1
ENSMUST00000147354.1
Lpar1


lysophosphatidic acid receptor 1


chr1_-_183147461 0.852 ENSMUST00000171366.1
Disp1
dispatched homolog 1 (Drosophila)
chr8_-_31918203 0.847 ENSMUST00000073884.4
Nrg1
neuregulin 1
chr12_+_55598917 0.842 ENSMUST00000051857.3
Insm2
insulinoma-associated 2
chr1_+_194619815 0.834 ENSMUST00000027952.5
Plxna2
plexin A2
chr17_-_48432723 0.815 ENSMUST00000046549.3
Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr4_+_98923810 0.812 ENSMUST00000030289.2
Usp1
ubiquitin specific peptidase 1
chr4_+_98923845 0.806 ENSMUST00000091358.4
Usp1
ubiquitin specific peptidase 1
chr6_+_15196949 0.802 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
Foxp2



forkhead box P2



chr13_-_53473074 0.798 ENSMUST00000021922.8
Msx2
msh homeobox 2
chr13_+_23544052 0.798 ENSMUST00000075558.2
Hist1h3f
histone cluster 1, H3f
chr8_-_67818284 0.795 ENSMUST00000120071.1
Psd3
pleckstrin and Sec7 domain containing 3
chr2_+_69897255 0.795 ENSMUST00000131553.1
Ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr11_+_75532099 0.791 ENSMUST00000169547.2
Slc43a2
solute carrier family 43, member 2
chr6_-_126645784 0.789 ENSMUST00000055168.3
Kcna1
potassium voltage-gated channel, shaker-related subfamily, member 1
chr7_+_126776939 0.788 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
Ypel3






yippee-like 3 (Drosophila)






chr5_+_34999046 0.779 ENSMUST00000114281.1
Rgs12
regulator of G-protein signaling 12
chr18_-_39487096 0.778 ENSMUST00000097592.2
ENSMUST00000115571.1
Nr3c1

nuclear receptor subfamily 3, group C, member 1

chr13_-_89742244 0.776 ENSMUST00000109543.2
ENSMUST00000159337.1
ENSMUST00000159910.1
ENSMUST00000109544.2
Vcan



versican



chr9_+_89199319 0.772 ENSMUST00000138109.1
Mthfs
5, 10-methenyltetrahydrofolate synthetase
chr14_+_54259227 0.766 ENSMUST00000041197.7
Abhd4
abhydrolase domain containing 4
chr9_-_55919605 0.766 ENSMUST00000037408.8
Scaper
S phase cyclin A-associated protein in the ER
chr8_-_67974567 0.751 ENSMUST00000098696.3
ENSMUST00000038959.9
ENSMUST00000093469.4
Psd3


pleckstrin and Sec7 domain containing 3


chr4_+_128993224 0.733 ENSMUST00000030583.6
ENSMUST00000102604.4
Ak2

adenylate kinase 2

chr2_-_121235689 0.733 ENSMUST00000142400.1
Trp53bp1
transformation related protein 53 binding protein 1
chr17_-_47834682 0.729 ENSMUST00000066368.6
Mdfi
MyoD family inhibitor
chr11_+_94327984 0.727 ENSMUST00000107818.2
ENSMUST00000051221.6
Ankrd40

ankyrin repeat domain 40

chr16_-_55283237 0.726 ENSMUST00000036412.3
Zpld1
zona pellucida like domain containing 1
chr6_+_88724667 0.720 ENSMUST00000163271.1
Mgll
monoglyceride lipase
chr11_-_107337556 0.716 ENSMUST00000040380.6
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr16_-_52452465 0.715 ENSMUST00000170035.1
ENSMUST00000164728.1
Alcam

activated leukocyte cell adhesion molecule

chr15_-_100424092 0.712 ENSMUST00000154676.1
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr16_-_52296924 0.697 ENSMUST00000167115.1
Alcam
activated leukocyte cell adhesion molecule
chr1_-_132707304 0.697 ENSMUST00000043189.7
Nfasc
neurofascin
chr10_-_86011833 0.696 ENSMUST00000105304.1
ENSMUST00000061699.5
Bpifc

BPI fold containing family C

chr14_+_53324632 0.693 ENSMUST00000178100.1
Trav7n-6
T cell receptor alpha variable 7N-6
chr11_-_26591729 0.689 ENSMUST00000109504.1
Vrk2
vaccinia related kinase 2
chr11_+_98798653 0.686 ENSMUST00000037930.6
Msl1
male-specific lethal 1 homolog (Drosophila)
chr1_+_170308802 0.685 ENSMUST00000056991.5
1700015E13Rik
RIKEN cDNA 1700015E13 gene
chr4_-_126968124 0.684 ENSMUST00000106108.2
Zmym4
zinc finger, MYM-type 4
chrM_+_9452 0.682 ENSMUST00000082411.1
mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chrX_-_143933204 0.679 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr16_-_97170707 0.679 ENSMUST00000056102.7
Dscam
Down syndrome cell adhesion molecule

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 10.0 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
2.5 7.4 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
1.9 5.8 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
1.5 6.1 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
1.5 4.6 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
1.1 3.4 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
0.9 2.8 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.9 2.8 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.8 3.4 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.8 5.0 GO:0006570 tyrosine metabolic process(GO:0006570)
0.7 3.4 GO:0051661 maintenance of centrosome location(GO:0051661)
0.7 2.7 GO:0021648 zygotic determination of anterior/posterior axis, embryo(GO:0007354) cranial nerve formation(GO:0021603) vestibulocochlear nerve morphogenesis(GO:0021648)
0.6 1.8 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.6 5.3 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.6 2.2 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.5 1.6 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.5 2.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.5 1.9 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.5 1.4 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.4 2.1 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.4 2.5 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) phosphate ion transmembrane transport(GO:0035435) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.4 1.2 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.4 1.9 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.4 0.4 GO:0003162 atrioventricular node development(GO:0003162)
0.4 6.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.3 14.6 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.3 0.9 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.3 2.7 GO:0097475 motor neuron migration(GO:0097475)
0.3 0.9 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.3 0.6 GO:0021856 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.3 1.4 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.3 0.8 GO:0016554 cytidine to uridine editing(GO:0016554)
0.3 0.8 GO:0048818 embryonic nail plate morphogenesis(GO:0035880) positive regulation of hair follicle maturation(GO:0048818) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364)
0.3 0.8 GO:0050975 sensory perception of touch(GO:0050975)
0.3 0.5 GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.2 1.5 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.2 5.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2 2.1 GO:0021830 interneuron migration from the subpallium to the cortex(GO:0021830)
0.2 0.7 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.2 0.7 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.2 0.9 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.2 0.6 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.2 2.5 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.2 1.0 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.2 0.6 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.2 3.0 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 0.8 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.2 1.9 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.2 0.6 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.2 1.3 GO:0030242 pexophagy(GO:0030242)
0.2 1.7 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) t-circle formation(GO:0090656)
0.2 2.4 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.2 0.5 GO:0021972 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.2 0.5 GO:0050748 negative regulation of receptor biosynthetic process(GO:0010871) transforming growth factor-beta secretion(GO:0038044) negative regulation of lipoprotein metabolic process(GO:0050748)
0.2 0.7 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.2 2.9 GO:0003334 keratinocyte development(GO:0003334)
0.2 1.0 GO:0002329 pre-B cell differentiation(GO:0002329)
0.2 1.0 GO:0034587 piRNA metabolic process(GO:0034587)
0.2 4.7 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2 0.7 GO:0007113 endomitotic cell cycle(GO:0007113)
0.2 2.5 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.2 1.6 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.2 0.8 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.2 0.9 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2 6.5 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2 0.5 GO:1903011 negative regulation of bone development(GO:1903011)
0.1 0.3 GO:0002865 negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865)
0.1 0.4 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.1 0.4 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.1 0.8 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 0.5 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.1 1.9 GO:0072189 ureter development(GO:0072189)
0.1 1.0 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 0.2 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.7 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 2.1 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.1 0.5 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.1 3.1 GO:0033194 response to hydroperoxide(GO:0033194)
0.1 0.6 GO:0046208 spermine catabolic process(GO:0046208)
0.1 7.7 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 0.5 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.1 1.0 GO:0048733 sebaceous gland development(GO:0048733)
0.1 0.9 GO:0030035 microspike assembly(GO:0030035)
0.1 1.8 GO:0045624 positive regulation of T-helper cell differentiation(GO:0045624)
0.1 0.5 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 0.4 GO:0090472 nerve growth factor production(GO:0032902) dibasic protein processing(GO:0090472)
0.1 0.8 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.1 1.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.7 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.5 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.2 GO:0036292 DNA rewinding(GO:0036292)
0.1 1.2 GO:0060013 righting reflex(GO:0060013)
0.1 0.5 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.1 2.4 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 0.8 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.8 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.1 0.6 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 0.4 GO:0042420 dopamine catabolic process(GO:0042420)
0.1 0.9 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 2.4 GO:0097352 autophagosome maturation(GO:0097352)
0.1 1.0 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 2.1 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.3 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.1 0.2 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.1 0.9 GO:0060539 diaphragm development(GO:0060539)
0.1 0.4 GO:1904659 glucose transmembrane transport(GO:1904659)
0.1 1.3 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.1 1.0 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 1.4 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 0.5 GO:0016584 nucleosome positioning(GO:0016584)
0.1 2.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 1.6 GO:0060009 Sertoli cell development(GO:0060009)
0.1 0.3 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 0.3 GO:0021502 neural fold elevation formation(GO:0021502)
0.1 0.6 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.4 GO:0051189 molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.1 0.9 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.3 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.1 0.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.2 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.1 1.1 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.6 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 0.5 GO:0043029 T cell homeostasis(GO:0043029)
0.1 0.6 GO:0051923 sulfation(GO:0051923)
0.1 1.6 GO:0007608 sensory perception of smell(GO:0007608)
0.1 0.1 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.1 0.7 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 2.5 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 0.7 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.3 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.0 0.5 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0 0.3 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.1 GO:0032570 response to progesterone(GO:0032570)
0.0 0.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.4 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112) negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.7 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.2 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.3 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.6 GO:0030953 astral microtubule organization(GO:0030953)
0.0 0.2 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 4.3 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 0.4 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.6 GO:0048041 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041)
0.0 0.9 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.3 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 1.0 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 0.2 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.7 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.2 GO:0086023 adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.0 0.9 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.4 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.7 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.0 0.5 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 1.1 GO:0009409 response to cold(GO:0009409)
0.0 0.3 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0 1.0 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 0.4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.2 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.7 GO:0071385 cellular response to glucocorticoid stimulus(GO:0071385)
0.0 0.4 GO:0010225 response to UV-C(GO:0010225)
0.0 0.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.4 GO:0045056 transcytosis(GO:0045056)
0.0 0.1 GO:0098734 protein depalmitoylation(GO:0002084) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005) macromolecule depalmitoylation(GO:0098734)
0.0 0.2 GO:0080009 mRNA methylation(GO:0080009)
0.0 1.0 GO:1901998 toxin transport(GO:1901998)
0.0 0.6 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.6 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0046689 response to mercury ion(GO:0046689)
0.0 0.0 GO:0042713 sperm ejaculation(GO:0042713) negative regulation of gastric acid secretion(GO:0060455)
0.0 0.3 GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307)
0.0 2.5 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 1.0 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 0.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.6 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 1.5 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.1 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.6 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.1 GO:0007602 phototransduction(GO:0007602)
0.0 0.9 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.2 GO:0034308 primary alcohol metabolic process(GO:0034308)
0.0 0.3 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.7 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.0 0.5 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.5 GO:0006284 base-excision repair(GO:0006284)
0.0 0.3 GO:0023058 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401) adaptation of signaling pathway(GO:0023058)
0.0 0.3 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.4 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.7 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 0.7 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.0 GO:0019886 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.6 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.7 GO:0006275 regulation of DNA replication(GO:0006275)
0.0 0.6 GO:0051058 negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 0.5 GO:0050868 negative regulation of T cell activation(GO:0050868)
0.0 0.1 GO:0006308 DNA catabolic process(GO:0006308)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.4 GO:0060187 cell pole(GO:0060187)
0.9 2.8 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.9 3.6 GO:0008623 CHRAC(GO:0008623)
0.7 3.4 GO:0036449 microtubule minus-end(GO:0036449)
0.4 2.4 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.3 4.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.3 25.8 GO:0070469 respiratory chain(GO:0070469)
0.3 1.4 GO:0070826 paraferritin complex(GO:0070826)
0.3 1.4 GO:0031523 Myb complex(GO:0031523)
0.2 2.4 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.2 1.4 GO:0005726 perichromatin fibrils(GO:0005726)
0.2 0.6 GO:0001772 immunological synapse(GO:0001772)
0.2 1.7 GO:0030478 actin cap(GO:0030478)
0.2 5.0 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.2 0.5 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
0.2 0.7 GO:0097454 Schwann cell microvillus(GO:0097454)
0.2 9.8 GO:0016459 myosin complex(GO:0016459)
0.2 0.5 GO:1990047 spindle matrix(GO:1990047)
0.1 1.0 GO:0070695 FHF complex(GO:0070695)
0.1 0.7 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.1 1.0 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1 0.7 GO:0072487 MSL complex(GO:0072487)
0.1 0.4 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 1.1 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 1.4 GO:0042101 T cell receptor complex(GO:0042101)
0.1 1.4 GO:0051286 cell tip(GO:0051286)
0.1 1.1 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.4 GO:0032807 DNA ligase IV complex(GO:0032807)
0.1 2.9 GO:0002102 podosome(GO:0002102)
0.1 0.3 GO:1990032 parallel fiber(GO:1990032)
0.1 0.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.4 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.1 1.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 1.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 1.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 8.5 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 4.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.8 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.4 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.7 GO:0043196 varicosity(GO:0043196)
0.0 0.6 GO:0000922 spindle pole(GO:0000922)
0.0 1.9 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.3 GO:0001739 sex chromatin(GO:0001739)
0.0 1.4 GO:0097440 apical dendrite(GO:0097440)
0.0 0.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 2.2 GO:0005769 early endosome(GO:0005769)
0.0 2.2 GO:0000786 nucleosome(GO:0000786)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 2.8 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.6 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.4 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.5 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.3 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.4 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.3 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.7 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0032797 SMN complex(GO:0032797)
0.0 1.1 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 2.7 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.0 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.0 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.4 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.5 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.1 GO:0000792 heterochromatin(GO:0000792)
0.0 0.4 GO:0032420 stereocilium(GO:0032420)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0042588 zymogen granule(GO:0042588)
0.0 0.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 2.2 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.8 GO:0043679 axon terminus(GO:0043679)
0.0 0.3 GO:0005921 gap junction(GO:0005921)
0.0 0.9 GO:0043204 perikaryon(GO:0043204)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.2 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 8.1 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.8 2.5 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.7 21.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.5 2.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.5 3.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.4 5.0 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.4 1.9 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.4 2.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.4 2.8 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.3 1.4 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.3 1.4 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.3 2.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.3 17.4 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 2.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 0.9 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.2 2.4 GO:0050693 LBD domain binding(GO:0050693)
0.2 1.0 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
0.2 1.7 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.2 0.8 GO:0004126 cytidine deaminase activity(GO:0004126)
0.2 1.4 GO:0034056 estrogen response element binding(GO:0034056)
0.2 0.6 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.2 0.6 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.2 0.6 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.2 0.8 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.2 0.6 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 1.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 9.9 GO:0030507 spectrin binding(GO:0030507)
0.2 0.5 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.2 1.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 1.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 0.6 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 5.0 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.7 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 1.9 GO:0045499 chemorepellent activity(GO:0045499)
0.1 2.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 0.4 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.4 GO:0005118 sevenless binding(GO:0005118)
0.1 1.0 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 2.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.1 GO:0005168 neurotrophin TRK receptor binding(GO:0005167) neurotrophin TRKA receptor binding(GO:0005168)
0.1 2.7 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.5 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.2 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 5.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 1.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.4 GO:0051378 serotonin binding(GO:0051378)
0.1 0.6 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.6 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.5 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.1 2.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.9 GO:0015197 peptide transporter activity(GO:0015197)
0.1 1.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.3 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1 2.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.4 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 0.3 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 2.7 GO:0070888 E-box binding(GO:0070888)
0.1 0.2 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1 0.3 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 0.6 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 0.6 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 1.2 GO:0070410 co-SMAD binding(GO:0070410)
0.1 1.7 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 2.4 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 0.7 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 1.3 GO:0001012 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.1 0.7 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.4 GO:0051400 BH domain binding(GO:0051400)
0.1 0.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 3.6 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.1 1.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 0.3 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 2.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.2 GO:0098809 nitrite reductase activity(GO:0098809)
0.1 0.6 GO:0046977 TAP binding(GO:0046977)
0.1 1.1 GO:0070412 R-SMAD binding(GO:0070412)
0.1 1.1 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 3.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 2.3 GO:0032452 histone demethylase activity(GO:0032452)
0.1 0.4 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.9 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.3 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.8 GO:0005542 folic acid binding(GO:0005542)
0.0 0.7 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.1 GO:0004534 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.6 GO:0070513 death domain binding(GO:0070513)
0.0 0.4 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 1.8 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.3 GO:0001515 opioid peptide activity(GO:0001515)
0.0 1.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.3 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 1.0 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.1 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.0 2.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.4 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 1.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 1.0 GO:0004386 helicase activity(GO:0004386)
0.0 0.2 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.4 GO:0043495 protein anchor(GO:0043495)
0.0 0.4 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.9 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 5.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.4 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 2.0 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 0.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.6 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.5 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.1 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.5 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.0 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 1.0 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 0.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 1.3 GO:0051117 ATPase binding(GO:0051117)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.4 GO:0050681 androgen receptor binding(GO:0050681)
0.0 1.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 2.3 GO:0003712 transcription cofactor activity(GO:0003712)
0.0 0.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 2.9 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.2 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.0 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 8.1 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.2 12.9 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.2 6.6 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.2 10.4 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 5.0 PID_ARF6_PATHWAY Arf6 signaling events
0.1 2.4 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.1 1.0 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.1 3.3 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.1 1.3 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.1 1.4 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.1 2.4 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 1.4 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 2.4 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.7 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.8 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 1.4 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.5 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 3.8 PID_E2F_PATHWAY E2F transcription factor network
0.0 1.9 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 2.2 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 3.0 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 2.3 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.8 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 1.0 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 2.5 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 4.2 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.9 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.2 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.4 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.0 1.0 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 1.2 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.4 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.6 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.0 0.7 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.9 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 0.3 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.2 PID_ATM_PATHWAY ATM pathway
0.0 0.1 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.6 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.2 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.7 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.2 1.6 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 1.1 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.1 3.8 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 4.2 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 2.2 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 0.7 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.4 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 6.0 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.1 0.1 REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 0.6 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.9 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.7 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.1 0.5 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 0.2 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 2.3 REACTOME_G1_PHASE Genes involved in G1 Phase
0.1 0.5 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 0.6 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.1 0.5 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.1 1.1 REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS Genes involved in Prolonged ERK activation events
0.1 1.1 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 0.1 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 1.6 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 5.0 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 2.1 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.0 1.0 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.0 1.7 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.8 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.3 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.5 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 0.6 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.2 REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 2.5 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.1 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.2 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.7 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.4 REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.2 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.5 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.5 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.7 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.0 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 4.5 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.1 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.8 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.2 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.8 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.2 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.2 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.0 0.2 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.3 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 0.2 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane