Motif ID: Nr0b1

Z-value: 1.123


Transcription factors associated with Nr0b1:

Gene SymbolEntrez IDGene Name
Nr0b1 ENSMUSG00000025056.4 Nr0b1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr0b1mm10_v2_chrX_+_86191764_861917820.241.4e-01Click!


Activity profile for motif Nr0b1.

activity profile for motif Nr0b1


Sorted Z-values histogram for motif Nr0b1

Sorted Z-values for motif Nr0b1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr0b1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_-_45844228 8.361 ENSMUST00000076333.5
 Phldb2
pleckstrin homology-like domain, family B, member 2
chr16_-_45844303 8.137 ENSMUST00000036355.6
 Phldb2
pleckstrin homology-like domain, family B, member 2
chr11_+_102604370 6.393 ENSMUST00000057893.5
 Fzd2
frizzled homolog 2 (Drosophila)
chr7_+_79500081 6.202 ENSMUST00000181511.2
ENSMUST00000182937.1
 AI854517

expressed sequence AI854517

chr7_+_79500018 5.615 ENSMUST00000182495.1
ENSMUST00000183043.1
 AI854517

expressed sequence AI854517

chr9_+_80165079 5.579 ENSMUST00000184480.1
 Myo6
myosin VI
chr9_+_80165013 4.911 ENSMUST00000035889.8
ENSMUST00000113268.1
 Myo6

myosin VI

chrX_-_145505175 4.754 ENSMUST00000143610.1
 Amot
angiomotin
chr1_-_9700209 4.370 ENSMUST00000088658.4
 Mybl1
myeloblastosis oncogene-like 1
chr5_+_64803513 4.277 ENSMUST00000165536.1
 Klf3
Kruppel-like factor 3 (basic)
chr4_-_132422484 3.690 ENSMUST00000102568.3
 Phactr4
phosphatase and actin regulator 4
chr3_-_123690806 3.666 ENSMUST00000154668.1
 Ndst3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr4_-_132422394 3.524 ENSMUST00000152271.1
ENSMUST00000084170.5
 Phactr4

phosphatase and actin regulator 4

chr17_-_70851189 3.350 ENSMUST00000059775.8
 Tgif1
TGFB-induced factor homeobox 1
chr10_-_81350389 3.309 ENSMUST00000020454.4
ENSMUST00000105324.2
ENSMUST00000154609.2
ENSMUST00000105323.1
 Hmg20b



high mobility group 20B



chr18_+_35829798 3.277 ENSMUST00000060722.6
 Cxxc5
CXXC finger 5
chr14_+_11553523 3.258 ENSMUST00000022264.6
 Ptprg
protein tyrosine phosphatase, receptor type, G
chr13_-_29984219 3.072 ENSMUST00000146092.1
 E2f3
E2F transcription factor 3
chr5_-_115436508 3.067 ENSMUST00000078701.3
 4930430O22Rik
RIKEN cDNA 4930430O22 gene
chr4_+_116221689 3.042 ENSMUST00000106490.2
 Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr4_+_116221633 3.022 ENSMUST00000030464.7
 Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr1_+_42697146 2.889 ENSMUST00000054883.2
 Pou3f3
POU domain, class 3, transcription factor 3
chr11_+_94328242 2.752 ENSMUST00000021227.5
 Ankrd40
ankyrin repeat domain 40
chr19_-_46039442 2.725 ENSMUST00000137771.1
 Ldb1
LIM domain binding 1
chr7_+_28180226 2.606 ENSMUST00000172467.1
 Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr11_+_94327984 2.526 ENSMUST00000107818.2
ENSMUST00000051221.6
 Ankrd40

ankyrin repeat domain 40

chr7_+_28180272 2.353 ENSMUST00000173223.1
 Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr4_-_123750236 2.322 ENSMUST00000102636.3
 Akirin1
akirin 1
chr4_+_116221590 2.315 ENSMUST00000147292.1
 Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr2_-_54085542 2.245 ENSMUST00000100089.2
 Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chr3_+_86224665 2.142 ENSMUST00000107635.1
 Lrba
LPS-responsive beige-like anchor
chr7_+_19094594 2.058 ENSMUST00000049454.5
 Six5
sine oculis-related homeobox 5
chr11_+_77930800 1.911 ENSMUST00000093995.3
ENSMUST00000000646.7
 Sez6

seizure related gene 6

chr6_+_47454320 1.898 ENSMUST00000031697.8
 Cul1
cullin 1
chr17_-_23745829 1.800 ENSMUST00000046525.8
 Kremen2
kringle containing transmembrane protein 2
chr7_+_82867327 1.748 ENSMUST00000082237.5
 Mex3b
mex3 homolog B (C. elegans)
chr5_-_99037035 1.739 ENSMUST00000031277.6
 Prkg2
protein kinase, cGMP-dependent, type II
chr5_-_99037342 1.611 ENSMUST00000161490.1
 Prkg2
protein kinase, cGMP-dependent, type II
chr15_-_38078842 1.594 ENSMUST00000110336.2
 Ubr5
ubiquitin protein ligase E3 component n-recognin 5
chr2_+_71786923 1.584 ENSMUST00000112101.1
ENSMUST00000028522.3
 Itga6

integrin alpha 6

chr5_+_30913398 1.459 ENSMUST00000031055.5
 Emilin1
elastin microfibril interfacer 1
chr17_+_29490812 1.420 ENSMUST00000024811.6
 Pim1
proviral integration site 1
chr13_+_94358943 1.386 ENSMUST00000022196.3
 Ap3b1
adaptor-related protein complex 3, beta 1 subunit
chr4_+_148130883 1.363 ENSMUST00000084129.2
 Mad2l2
MAD2 mitotic arrest deficient-like 2
chr4_-_138913915 1.347 ENSMUST00000097830.3
 Otud3
OTU domain containing 3
chr17_-_80728026 1.285 ENSMUST00000112389.2
ENSMUST00000025089.7
 Map4k3

mitogen-activated protein kinase kinase kinase kinase 3

chr14_+_75845296 1.253 ENSMUST00000142061.1
 Tpt1
tumor protein, translationally-controlled 1
chr18_+_80046854 1.253 ENSMUST00000070219.7
 Pard6g
par-6 partitioning defective 6 homolog gamma (C. elegans)
chr11_+_50237002 1.221 ENSMUST00000180443.1
 Gm26542
predicted gene, 26542
chr16_+_44173239 1.216 ENSMUST00000119746.1
 Gm608
predicted gene 608
chr12_+_49385174 1.194 ENSMUST00000110746.1
 3110039M20Rik
RIKEN cDNA 3110039M20 gene
chr2_+_129198757 1.179 ENSMUST00000028880.3
 Slc20a1
solute carrier family 20, member 1
chr1_+_59764264 1.141 ENSMUST00000087435.5
 Bmpr2
bone morphogenetic protein receptor, type II (serine/threonine kinase)
chr5_+_110230975 1.117 ENSMUST00000031474.7
ENSMUST00000086674.5
 Ankle2

ankyrin repeat and LEM domain containing 2

chr7_-_65371210 1.108 ENSMUST00000102592.3
 Tjp1
tight junction protein 1
chr11_-_70687917 0.989 ENSMUST00000108545.2
ENSMUST00000120261.1
ENSMUST00000036299.7
ENSMUST00000119120.1
ENSMUST00000100933.3
 Camta2




calmodulin binding transcription activator 2




chr11_+_107547925 0.960 ENSMUST00000100305.1
ENSMUST00000075012.1
ENSMUST00000106746.1
 Helz


helicase with zinc finger domain


chr13_-_94358818 0.949 ENSMUST00000059598.2
 Gm9776
predicted gene 9776
chr11_+_105181793 0.939 ENSMUST00000092537.3
ENSMUST00000015107.6
ENSMUST00000145048.1
 Tlk2


tousled-like kinase 2 (Arabidopsis)


chr13_-_64274879 0.921 ENSMUST00000109770.1
 Cdc14b
CDC14 cell division cycle 14B
chr4_-_135971894 0.831 ENSMUST00000105852.1
 Lypla2
lysophospholipase 2
chr11_-_74723829 0.776 ENSMUST00000102520.2
 Pafah1b1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr1_+_140246216 0.723 ENSMUST00000119786.1
ENSMUST00000120796.1
ENSMUST00000060201.8
ENSMUST00000120709.1
 Kcnt2



potassium channel, subfamily T, member 2



chr15_+_35371498 0.718 ENSMUST00000048646.7
 Vps13b
vacuolar protein sorting 13B (yeast)
chr11_+_24078173 0.710 ENSMUST00000109514.1
 Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chr19_+_45015198 0.666 ENSMUST00000179108.1
 Lzts2
leucine zipper, putative tumor suppressor 2
chr15_+_80711292 0.616 ENSMUST00000067689.7
 Tnrc6b
trinucleotide repeat containing 6b
chr2_+_4718145 0.616 ENSMUST00000056914.6
 Bend7
BEN domain containing 7
chr4_-_148130678 0.591 ENSMUST00000030862.4
 Draxin
dorsal inhibitory axon guidance protein
chr5_+_121711609 0.573 ENSMUST00000051950.7
 Atxn2
ataxin 2
chr4_-_129696817 0.552 ENSMUST00000102588.3
 Tmem39b
transmembrane protein 39b
chr17_+_34898463 0.494 ENSMUST00000114033.2
ENSMUST00000078061.6
 Ehmt2

euchromatic histone lysine N-methyltransferase 2

chr8_-_95434869 0.430 ENSMUST00000034249.6
 Gtl3
gene trap locus 3
chr9_-_44881274 0.394 ENSMUST00000002095.3
ENSMUST00000114689.1
ENSMUST00000128768.1
 Kmt2a


lysine (K)-specific methyltransferase 2A


chr11_+_105181527 0.337 ENSMUST00000106941.2
 Tlk2
tousled-like kinase 2 (Arabidopsis)
chr2_+_85037448 0.324 ENSMUST00000168266.1
ENSMUST00000130729.1
 Ssrp1

structure specific recognition protein 1

chr11_+_23306884 0.309 ENSMUST00000180046.1
 Usp34
ubiquitin specific peptidase 34
chr2_+_30066419 0.228 ENSMUST00000067996.6
 Set
SET nuclear oncogene
chr19_-_6077183 0.214 ENSMUST00000025711.5
ENSMUST00000160590.1
 Vps51

vacuolar protein sorting 51 homolog (S. cerevisiae)

chr8_-_85080652 0.203 ENSMUST00000152785.1
 Wdr83
WD repeat domain containing 83
chr8_-_85080679 0.160 ENSMUST00000093357.5
 Wdr83
WD repeat domain containing 83
chr11_+_24078022 0.135 ENSMUST00000000881.6
 Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chr11_+_23306910 0.123 ENSMUST00000137823.1
 Usp34
ubiquitin specific peptidase 34
chr13_-_55488038 0.114 ENSMUST00000109921.2
ENSMUST00000109923.2
ENSMUST00000021950.8
 Dbn1


drebrin 1


chr7_+_19359740 0.082 ENSMUST00000140836.1
 Ppp1r13l
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chr10_+_116301374 0.082 ENSMUST00000092167.5
 Ptprb
protein tyrosine phosphatase, receptor type, B
chr17_-_26508463 0.039 ENSMUST00000025025.6
 Dusp1
dual specificity phosphatase 1
chr8_-_105707933 0.012 ENSMUST00000013299.9
 Enkd1
enkurin domain containing 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 16.5 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
1.8 7.2 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
1.3 6.4 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223) hard palate development(GO:0060022)
1.2 4.8 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.8 10.5 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.7 2.9 GO:0072236 DCT cell differentiation(GO:0072069) metanephric loop of Henle development(GO:0072236) metanephric DCT cell differentiation(GO:0072240)
0.7 2.7 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.6 3.7 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.5 1.6 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.5 3.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.5 3.3 GO:2001225 cellular hypotonic response(GO:0071476) regulation of chloride transport(GO:2001225)
0.5 1.4 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.4 1.3 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.4 1.1 GO:0014916 regulation of lung blood pressure(GO:0014916) negative regulation of cell proliferation involved in heart morphogenesis(GO:2000137) cell proliferation involved in heart valve development(GO:2000793)
0.4 1.1 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.3 1.4 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.3 1.3 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.3 1.7 GO:0072697 protein localization to cell cortex(GO:0072697)
0.3 1.4 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.3 1.6 GO:0035878 nail development(GO:0035878)
0.3 0.8 GO:0043622 cortical microtubule organization(GO:0043622)
0.2 0.5 GO:0036166 phenotypic switching(GO:0036166)
0.2 0.8 GO:1904800 regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800)
0.2 8.4 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.2 3.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 3.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.2 2.1 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.1 0.8 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 5.0 GO:0007520 myoblast fusion(GO:0007520)
0.1 1.3 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.9 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 0.4 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674) positive regulation of response to drug(GO:2001025)
0.1 1.1 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 1.9 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.1 1.2 GO:0006817 phosphate ion transport(GO:0006817)
0.1 2.8 GO:1901998 toxin transport(GO:1901998)
0.1 0.6 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 1.9 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 1.5 GO:0070207 protein homotrimerization(GO:0070207)
0.0 1.0 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.1 GO:0010643 cell communication by chemical coupling(GO:0010643) negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.0 0.6 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.6 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 1.8 GO:0030279 negative regulation of ossification(GO:0030279)
0.0 0.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 2.2 GO:0007050 cell cycle arrest(GO:0007050)
0.0 2.1 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 1.3 GO:0034612 response to tumor necrosis factor(GO:0034612)
0.0 1.7 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 16.5 GO:0045180 basal cortex(GO:0045180)
0.8 3.3 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.5 1.9 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.4 10.5 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.4 8.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.2 1.6 GO:0030056 hemidesmosome(GO:0030056)
0.1 1.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.8 GO:0000235 astral microtubule(GO:0000235)
0.1 1.3 GO:0045298 tubulin complex(GO:0045298)
0.1 1.4 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 4.8 GO:0008180 COP9 signalosome(GO:0008180)
0.1 0.6 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 1.5 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 1.9 GO:0097440 apical dendrite(GO:0097440)
0.0 0.2 GO:1990745 EARP complex(GO:1990745)
0.0 7.0 GO:0030027 lamellipodium(GO:0030027)
0.0 1.3 GO:0005882 intermediate filament(GO:0005882)
0.0 5.7 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.1 GO:0009925 basal plasma membrane(GO:0009925)
0.0 3.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 6.3 GO:0005925 focal adhesion(GO:0005925)
0.0 0.4 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 2.7 GO:0031252 cell leading edge(GO:0031252)
0.0 1.3 GO:0005923 bicellular tight junction(GO:0005923)
0.0 2.3 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 7.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
1.2 8.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
1.0 4.8 GO:0043532 angiostatin binding(GO:0043532)
0.9 3.7 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.8 3.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.5 4.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.4 1.2 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
0.3 2.7 GO:0030274 LIM domain binding(GO:0030274)
0.3 1.5 GO:0098634 protein binding involved in cell-matrix adhesion(GO:0098634)
0.3 6.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 1.2 GO:0038132 neuregulin binding(GO:0038132)
0.2 4.7 GO:0008432 JUN kinase binding(GO:0008432)
0.2 1.1 GO:0098821 BMP receptor activity(GO:0098821)
0.2 0.8 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 3.3 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 1.1 GO:0071253 connexin binding(GO:0071253)
0.1 1.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 1.6 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.4 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 1.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 2.9 GO:0071837 HMG box domain binding(GO:0071837)
0.1 1.7 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.8 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 5.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 10.5 GO:0003774 motor activity(GO:0003774)
0.1 0.5 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.7 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 1.4 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 2.1 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.6 GO:0050692 DBD domain binding(GO:0050692)
0.0 4.3 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.1 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 7.1 GO:0045296 cadherin binding(GO:0045296)
0.0 1.4 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 3.1 GO:0001047 core promoter binding(GO:0001047)
0.0 11.4 GO:0043565 sequence-specific DNA binding(GO:0043565)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 8.2 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.2 1.6 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 8.4 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.2 10.2 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 1.1 PID_ALK2_PATHWAY ALK2 signaling events
0.1 1.4 PID_IL5_PATHWAY IL5-mediated signaling events
0.1 4.4 PID_IL4_2PATHWAY IL4-mediated signaling events
0.1 1.9 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.0 1.1 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 3.1 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 3.3 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 2.2 PID_PLK1_PATHWAY PLK1 signaling events
0.0 1.3 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 0.8 PID_REELIN_PATHWAY Reelin signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 8.4 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.6 10.5 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.3 3.1 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.2 1.9 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.2 5.9 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.2 3.3 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 3.7 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 3.3 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 6.3 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.1 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 1.3 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 3.3 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.6 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 1.4 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.5 REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.3 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.0 1.2 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.8 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes