Motif ID: Nr2c1

Z-value: 0.700


Transcription factors associated with Nr2c1:

Gene SymbolEntrez IDGene Name
Nr2c1 ENSMUSG00000005897.8 Nr2c1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr2c1mm10_v2_chr10_+_94147982_94148023-0.343.4e-02Click!


Activity profile for motif Nr2c1.

activity profile for motif Nr2c1


Sorted Z-values histogram for motif Nr2c1

Sorted Z-values for motif Nr2c1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2c1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_29411736 4.712 ENSMUST00000115236.1
Ntm
neurotrimin
chr9_-_29412204 4.549 ENSMUST00000115237.1
Ntm
neurotrimin
chr15_+_80091320 4.414 ENSMUST00000009728.6
ENSMUST00000009727.5
Syngr1

synaptogyrin 1

chr15_+_3270767 4.340 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
Sepp1



selenoprotein P, plasma, 1



chr10_+_58813359 4.128 ENSMUST00000135526.2
ENSMUST00000153031.1
Sh3rf3

SH3 domain containing ring finger 3

chr6_+_22875496 3.928 ENSMUST00000090568.3
Ptprz1
protein tyrosine phosphatase, receptor type Z, polypeptide 1
chr9_-_21037775 3.835 ENSMUST00000180870.1
Gm26592
predicted gene, 26592
chr4_-_46991842 3.545 ENSMUST00000107749.2
Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr3_+_68572245 2.941 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1
chr11_-_76577701 2.874 ENSMUST00000176179.1
Abr
active BCR-related gene
chr7_+_45896941 2.708 ENSMUST00000069772.7
ENSMUST00000107716.1
Tmem143

transmembrane protein 143

chr11_+_75193783 2.693 ENSMUST00000102514.3
Rtn4rl1
reticulon 4 receptor-like 1
chr15_-_79505241 2.610 ENSMUST00000057801.6
Kcnj4
potassium inwardly-rectifying channel, subfamily J, member 4
chr10_-_86498836 2.514 ENSMUST00000120638.1
Syn3
synapsin III
chr12_+_61523889 2.130 ENSMUST00000119481.1
ENSMUST00000055815.7
Lrfn5

leucine rich repeat and fibronectin type III domain containing 5

chr14_+_75136326 1.875 ENSMUST00000145303.1
Lcp1
lymphocyte cytosolic protein 1
chr7_+_45897429 1.796 ENSMUST00000140243.1
Tmem143
transmembrane protein 143
chr1_-_155417283 1.735 ENSMUST00000027741.5
Xpr1
xenotropic and polytropic retrovirus receptor 1
chr11_-_62281342 1.625 ENSMUST00000072916.4
Zswim7
zinc finger SWIM-type containing 7
chr17_-_46032366 1.599 ENSMUST00000071648.5
ENSMUST00000142351.2
ENSMUST00000167860.1
Vegfa


vascular endothelial growth factor A


chr10_-_86498872 1.588 ENSMUST00000121789.1
Syn3
synapsin III
chr6_-_83054415 1.421 ENSMUST00000113962.1
ENSMUST00000089645.6
ENSMUST00000113963.1
Htra2


HtrA serine peptidase 2


chr4_+_127172866 1.367 ENSMUST00000106094.2
Dlgap3
discs, large (Drosophila) homolog-associated protein 3
chr11_-_3504766 1.338 ENSMUST00000044507.5
Inpp5j
inositol polyphosphate 5-phosphatase J
chr17_-_35910032 1.312 ENSMUST00000141662.1
ENSMUST00000056034.6
ENSMUST00000077494.6
ENSMUST00000149277.1
ENSMUST00000061052.5
Atat1




alpha tubulin acetyltransferase 1




chr1_+_133309778 1.303 ENSMUST00000094557.4
ENSMUST00000183457.1
ENSMUST00000183738.1
ENSMUST00000185157.1
ENSMUST00000184603.1
Golt1a

Kiss1

GOLT1A
golgi transport 1 homolog A (S. cerevisiae)

KiSS-1 metastasis-suppressor

KISS1 isoform e
chr12_-_83487708 1.269 ENSMUST00000177959.1
ENSMUST00000178756.1
Dpf3

D4, zinc and double PHD fingers, family 3

chr13_-_73328442 1.254 ENSMUST00000022097.5
Ndufs6
NADH dehydrogenase (ubiquinone) Fe-S protein 6
chr15_-_79141197 1.224 ENSMUST00000169604.1
1700088E04Rik
RIKEN cDNA 1700088E04 gene
chr5_+_117120120 1.191 ENSMUST00000111978.1
Taok3
TAO kinase 3
chr1_+_58973521 1.189 ENSMUST00000114296.1
ENSMUST00000027185.4
Stradb

STE20-related kinase adaptor beta

chr7_+_110768169 1.143 ENSMUST00000170374.1
Ampd3
adenosine monophosphate deaminase 3
chr17_-_35909626 1.137 ENSMUST00000141132.1
Atat1
alpha tubulin acetyltransferase 1
chr4_-_129440800 1.119 ENSMUST00000053042.5
ENSMUST00000106046.1
Zbtb8b

zinc finger and BTB domain containing 8b

chr12_+_83987854 1.118 ENSMUST00000021649.7
Acot2
acyl-CoA thioesterase 2
chr1_+_195017399 1.098 ENSMUST00000181273.1
A330023F24Rik
RIKEN cDNA A330023F24 gene
chr13_+_31558157 1.055 ENSMUST00000042118.8
Foxq1
forkhead box Q1
chr2_+_92375306 1.037 ENSMUST00000028650.8
Pex16
peroxisomal biogenesis factor 16
chr7_+_46397648 1.033 ENSMUST00000160433.1
Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr11_-_26210553 1.022 ENSMUST00000101447.3
5730522E02Rik
RIKEN cDNA 5730522E02 gene
chr7_+_30232032 0.967 ENSMUST00000149654.1
Polr2i
polymerase (RNA) II (DNA directed) polypeptide I
chr8_+_119394866 0.954 ENSMUST00000098367.4
Mlycd
malonyl-CoA decarboxylase
chrX_-_59567348 0.944 ENSMUST00000124402.1
Fgf13
fibroblast growth factor 13
chr2_-_29253001 0.883 ENSMUST00000071201.4
Ntng2
netrin G2
chr1_+_58586381 0.875 ENSMUST00000027193.8
Ndufb3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex 3
chrX_+_10485121 0.873 ENSMUST00000076354.6
ENSMUST00000115526.1
Tspan7

tetraspanin 7

chr12_+_4082574 0.867 ENSMUST00000020986.7
Dnajc27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr19_-_45998479 0.853 ENSMUST00000045396.7
9130011E15Rik
RIKEN cDNA 9130011E15 gene
chr6_+_125145235 0.810 ENSMUST00000119527.1
ENSMUST00000088276.6
ENSMUST00000051171.7
ENSMUST00000117675.1
Iffo1



intermediate filament family orphan 1



chr7_-_45921418 0.769 ENSMUST00000038876.5
Emp3
epithelial membrane protein 3
chr16_-_44139630 0.750 ENSMUST00000137557.1
ENSMUST00000147025.1
Atp6v1a

ATPase, H+ transporting, lysosomal V1 subunit A

chr6_+_124663027 0.725 ENSMUST00000004381.7
Lpcat3
lysophosphatidylcholine acyltransferase 3
chr16_-_44139196 0.709 ENSMUST00000063661.6
ENSMUST00000114666.2
Atp6v1a

ATPase, H+ transporting, lysosomal V1 subunit A

chr10_-_67548944 0.684 ENSMUST00000075686.4
Ado
2-aminoethanethiol (cysteamine) dioxygenase
chr6_+_83054653 0.661 ENSMUST00000092618.6
Aup1
ancient ubiquitous protein 1
chr2_+_29869484 0.659 ENSMUST00000047521.6
ENSMUST00000134152.1
Cercam

cerebral endothelial cell adhesion molecule

chr14_+_54360826 0.640 ENSMUST00000000985.5
Oxa1l
oxidase assembly 1-like
chr1_+_74284930 0.630 ENSMUST00000113805.1
ENSMUST00000027370.6
ENSMUST00000087226.4
Pnkd


paroxysmal nonkinesiogenic dyskinesia


chr14_+_57798156 0.613 ENSMUST00000128764.1
Sap18
Sin3-associated polypeptide 18
chr5_-_137741601 0.611 ENSMUST00000119498.1
ENSMUST00000061789.7
Nyap1

neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1

chr11_+_62281457 0.574 ENSMUST00000101075.4
ENSMUST00000050646.6
Ttc19

tetratricopeptide repeat domain 19

chr7_-_45920830 0.570 ENSMUST00000164119.1
Emp3
epithelial membrane protein 3
chr4_+_133039482 0.538 ENSMUST00000105914.1
Ahdc1
AT hook, DNA binding motif, containing 1
chr2_+_130406478 0.537 ENSMUST00000055421.4
Tmem239
transmembrane 239
chr11_-_50325599 0.535 ENSMUST00000179865.1
ENSMUST00000020637.8
Canx

calnexin

chr14_+_57798182 0.527 ENSMUST00000111269.1
Sap18
Sin3-associated polypeptide 18
chr7_+_30232310 0.527 ENSMUST00000108193.1
ENSMUST00000108192.1
Polr2i

polymerase (RNA) II (DNA directed) polypeptide I

chr1_-_58586191 0.519 ENSMUST00000038372.7
ENSMUST00000097724.3
ENSMUST00000161000.1
ENSMUST00000161600.1
Fam126b



family with sequence similarity 126, member B



chr15_-_98093245 0.500 ENSMUST00000180657.1
Senp1
SUMO1/sentrin specific peptidase 1
chr17_-_35235755 0.483 ENSMUST00000048994.6
Nfkbil1
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor like 1
chr16_-_4523056 0.481 ENSMUST00000090500.3
ENSMUST00000023161.7
Srl

sarcalumenin

chr4_-_130174691 0.478 ENSMUST00000132545.2
ENSMUST00000175992.1
ENSMUST00000105999.2
Tinagl1


tubulointerstitial nephritis antigen-like 1


chr3_+_107631322 0.473 ENSMUST00000106703.1
Gm10961
predicted gene 10961
chr11_-_107337556 0.464 ENSMUST00000040380.6
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chrX_+_100729917 0.428 ENSMUST00000019503.7
Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr19_-_3912711 0.416 ENSMUST00000075092.6
Ndufs8
NADH dehydrogenase (ubiquinone) Fe-S protein 8
chr19_+_4962306 0.407 ENSMUST00000025836.4
Mrpl11
mitochondrial ribosomal protein L11
chr3_+_58525821 0.386 ENSMUST00000029387.8
Eif2a
eukaryotic translation initiation factor 2A
chr19_+_4097392 0.352 ENSMUST00000174514.1
ENSMUST00000174149.1
Cdk2ap2

CDK2-associated protein 2

chr11_+_4986824 0.345 ENSMUST00000009234.9
ENSMUST00000109897.1
Ap1b1

adaptor protein complex AP-1, beta 1 subunit

chr7_-_28598140 0.332 ENSMUST00000108283.1
ENSMUST00000040531.8
Pak4
Samd4b
p21 protein (Cdc42/Rac)-activated kinase 4
sterile alpha motif domain containing 4B
chr1_-_74284636 0.326 ENSMUST00000178235.1
ENSMUST00000006462.7
Aamp

angio-associated migratory protein

chr13_-_9878998 0.314 ENSMUST00000063093.9
Chrm3
cholinergic receptor, muscarinic 3, cardiac
chr7_+_101394361 0.312 ENSMUST00000154239.1
ENSMUST00000098243.2
Arap1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

chr17_-_34028044 0.303 ENSMUST00000045467.7
ENSMUST00000114303.3
H2-Ke6

H2-K region expressed gene 6

chr15_+_81811414 0.300 ENSMUST00000023024.7
Tef
thyrotroph embryonic factor
chr1_+_12718496 0.275 ENSMUST00000088585.3
Sulf1
sulfatase 1
chr4_+_156215920 0.272 ENSMUST00000105572.1
2310042D19Rik
RIKEN cDNA 2310042D19 gene
chr6_-_142964404 0.266 ENSMUST00000032421.3
St8sia1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr7_+_30712209 0.260 ENSMUST00000005692.6
ENSMUST00000170371.1
Atp4a

ATPase, H+/K+ exchanging, gastric, alpha polypeptide

chr15_-_93336800 0.247 ENSMUST00000080299.6
Yaf2
YY1 associated factor 2
chr11_+_3488275 0.244 ENSMUST00000064265.6
Pla2g3
phospholipase A2, group III
chr10_+_59395632 0.244 ENSMUST00000092511.4
Gm10273
predicted pseudogene 10273
chr4_-_11076160 0.242 ENSMUST00000058183.8
Ndufaf6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr10_+_93589413 0.215 ENSMUST00000181835.1
4933408J17Rik
RIKEN cDNA 4933408J17 gene
chr8_+_95825353 0.206 ENSMUST00000074053.4
Gm10094
predicted gene 10094
chr10_+_13008442 0.204 ENSMUST00000105139.3
Sf3b5
splicing factor 3b, subunit 5
chr1_+_180726019 0.203 ENSMUST00000027780.4
Acbd3
acyl-Coenzyme A binding domain containing 3
chr7_-_79842287 0.190 ENSMUST00000049004.6
Anpep
alanyl (membrane) aminopeptidase
chr10_-_93589621 0.162 ENSMUST00000020203.6
Snrpf
small nuclear ribonucleoprotein polypeptide F
chr7_+_28881656 0.130 ENSMUST00000066880.4
Capn12
calpain 12
chr15_+_89429560 0.111 ENSMUST00000168646.1
C730034F03Rik
RIKEN cDNA C730034F03 gene
chr11_-_97766508 0.105 ENSMUST00000107579.1
ENSMUST00000018685.2
Cwc25

CWC25 spliceosome-associated protein homolog (S. cerevisiae)

chr1_-_172632931 0.098 ENSMUST00000027826.5
Dusp23
dual specificity phosphatase 23
chr11_+_116853752 0.090 ENSMUST00000021173.7
Mfsd11
major facilitator superfamily domain containing 11
chr15_+_79141324 0.082 ENSMUST00000040077.6
Polr2f
polymerase (RNA) II (DNA directed) polypeptide F
chr5_-_137072254 0.066 ENSMUST00000077523.3
ENSMUST00000041388.4
Serpine1

serine (or cysteine) peptidase inhibitor, clade E, member 1

chr16_+_44139821 0.064 ENSMUST00000159514.1
ENSMUST00000161326.1
ENSMUST00000063520.8
ENSMUST00000063542.7
Naa50



N(alpha)-acetyltransferase 50, NatE catalytic subunit



chr14_+_20674311 0.062 ENSMUST00000048657.8
Sec24c
Sec24 related gene family, member C (S. cerevisiae)
chr13_-_93192270 0.055 ENSMUST00000048702.5
Papd4
PAP associated domain containing 4
chr14_+_57798637 0.047 ENSMUST00000111267.1
Sap18
Sin3-associated polypeptide 18
chr3_+_58526303 0.046 ENSMUST00000138848.1
Eif2a
eukaryotic translation initiation factor 2A
chr2_+_106695594 0.028 ENSMUST00000016530.7
Mpped2
metallophosphoesterase domain containing 2
chr17_-_12992188 0.008 ENSMUST00000159986.1
Wtap
Wilms' tumour 1-associating protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.8 2.4 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.6 2.9 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.5 1.6 GO:1902336 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336)
0.5 1.5 GO:0001193 maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
0.3 1.3 GO:0032275 luteinizing hormone secretion(GO:0032275) positive regulation of gonadotropin secretion(GO:0032278)
0.3 1.0 GO:0015938 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
0.3 1.7 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) phosphate ion transmembrane transport(GO:0035435) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.3 0.9 GO:0045204 MAPK export from nucleus(GO:0045204)
0.2 4.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 0.6 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.2 1.4 GO:1901525 negative regulation of macromitophagy(GO:1901525) regulation of mitophagy in response to mitochondrial depolarization(GO:1904923)
0.2 1.0 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.2 1.1 GO:0032264 IMP salvage(GO:0032264)
0.2 2.9 GO:0001553 luteinization(GO:0001553)
0.1 0.9 GO:0098909 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 2.1 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 3.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 1.9 GO:0051639 actin filament network formation(GO:0051639)
0.1 1.1 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 0.5 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 2.6 GO:0010107 potassium ion import(GO:0010107)
0.1 1.0 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1 0.5 GO:0014874 response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.1 1.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.5 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.1 0.4 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 0.3 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 1.3 GO:0032060 bleb assembly(GO:0032060)
0.1 0.6 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.2 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 1.3 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 1.2 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.6 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 9.3 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.0 0.5 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.3 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 1.5 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.4 GO:0090527 actin filament reorganization(GO:0090527)
0.0 1.1 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 1.2 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.1 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538)
0.0 4.1 GO:0099643 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.0 0.4 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 3.6 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.3 GO:0010155 regulation of proton transport(GO:0010155)
0.0 0.7 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.3 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.5 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.2 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.0 0.7 GO:0097006 regulation of plasma lipoprotein particle levels(GO:0097006)
0.0 0.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.3 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 1.6 GO:0050821 protein stabilization(GO:0050821)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0072534 perineuronal net(GO:0072534)
0.7 3.5 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.3 2.4 GO:0097427 microtubule bundle(GO:0097427)
0.2 1.5 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.7 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 1.1 GO:0061574 ASAP complex(GO:0061574)
0.1 8.5 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 3.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 9.3 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.4 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 1.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 1.9 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.5 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 2.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 1.3 GO:0071565 nBAF complex(GO:0071565)
0.0 0.4 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.2 GO:0031983 vesicle lumen(GO:0031983)
0.0 1.0 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.2 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.0 0.8 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.6 GO:1990391 DNA repair complex(GO:1990391)
0.0 1.0 GO:0030673 axolemma(GO:0030673)
0.0 1.2 GO:0016235 aggresome(GO:0016235)
0.0 0.3 GO:0032279 asymmetric synapse(GO:0032279)
0.0 1.6 GO:0005604 basement membrane(GO:0005604)
0.0 1.3 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.1 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.8 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.9 GO:0014704 intercalated disc(GO:0014704)
0.0 2.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.5 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.6 1.7 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.5 1.6 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.4 1.3 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.4 2.4 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.3 2.7 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 0.5 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.2 1.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 2.6 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 0.7 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 3.9 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 0.6 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 1.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 1.5 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 0.3 GO:0070404 NADH binding(GO:0070404)
0.1 1.0 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 0.7 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 0.7 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.4 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 1.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.5 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 1.6 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.5 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.3 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.3 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 2.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.5 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 1.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.0 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.3 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 1.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.1 GO:0043022 ribosome binding(GO:0043022)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 3.2 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 1.2 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 0.9 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 1.2 PID_LKB1_PATHWAY LKB1 signaling events
0.0 1.1 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.5 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.1 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.3 3.5 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.6 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.6 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 0.7 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.1 2.6 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.2 REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 1.1 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.1 1.5 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.5 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.0 0.3 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 2.5 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 2.9 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 0.3 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.0 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.3 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.2 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs