Motif ID: Obox3

Z-value: 0.419


Transcription factors associated with Obox3:

Gene SymbolEntrez IDGene Name
Obox3 ENSMUSG00000066772.6 Obox3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Obox3mm10_v2_chr7_-_15627876_156278760.019.4e-01Click!


Activity profile for motif Obox3.

activity profile for motif Obox3


Sorted Z-values histogram for motif Obox3

Sorted Z-values for motif Obox3



Network of associatons between targets according to the STRING database.



First level regulatory network of Obox3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_74013442 1.566 ENSMUST00000098006.2
ENSMUST00000084474.5
 Frmd3

FERM domain containing 3

chr1_+_140246216 1.361 ENSMUST00000119786.1
ENSMUST00000120796.1
ENSMUST00000060201.8
ENSMUST00000120709.1
 Kcnt2



potassium channel, subfamily T, member 2



chr14_-_19977249 1.189 ENSMUST00000160013.1
 Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr2_+_69722797 1.062 ENSMUST00000090858.3
 Ppig
peptidyl-prolyl isomerase G (cyclophilin G)
chr13_-_23369156 1.020 ENSMUST00000125328.1
ENSMUST00000145451.1
ENSMUST00000050101.2
 Zfp322a


zinc finger protein 322A


chr14_-_19977151 0.989 ENSMUST00000055100.7
ENSMUST00000162425.1
 Gng2

guanine nucleotide binding protein (G protein), gamma 2

chr14_-_19977040 0.986 ENSMUST00000159028.1
 Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr19_+_3767397 0.954 ENSMUST00000113974.4
ENSMUST00000113972.2
ENSMUST00000113973.1
ENSMUST00000113977.2
ENSMUST00000052699.6
ENSMUST00000113968.2
 Suv420h1





suppressor of variegation 4-20 homolog 1 (Drosophila)





chr18_+_42511496 0.939 ENSMUST00000025375.7
 Tcerg1
transcription elongation regulator 1 (CA150)
chr1_-_52232296 0.931 ENSMUST00000114512.1
 Gls
glutaminase
chr14_+_61138445 0.916 ENSMUST00000089394.3
ENSMUST00000119509.1
 Sacs

sacsin

chr2_+_136892168 0.868 ENSMUST00000099311.2
 Slx4ip
SLX4 interacting protein
chr6_+_4902913 0.864 ENSMUST00000175889.1
ENSMUST00000168998.2
 Ppp1r9a

protein phosphatase 1, regulatory (inhibitor) subunit 9A

chr6_-_91807424 0.855 ENSMUST00000162300.1
 Grip2
glutamate receptor interacting protein 2
chr10_+_111972664 0.832 ENSMUST00000163048.1
ENSMUST00000174653.1
 Krr1

KRR1, small subunit (SSU) processome component, homolog (yeast)

chr11_-_70459957 0.728 ENSMUST00000019064.2
 Cxcl16
chemokine (C-X-C motif) ligand 16
chr6_-_91807318 0.666 ENSMUST00000159684.1
 Grip2
glutamate receptor interacting protein 2
chr19_+_3768112 0.640 ENSMUST00000005518.9
ENSMUST00000113967.1
ENSMUST00000152935.1
ENSMUST00000176262.1
ENSMUST00000176407.1
ENSMUST00000176926.1
ENSMUST00000176512.1
 Suv420h1






suppressor of variegation 4-20 homolog 1 (Drosophila)






chr9_-_50617228 0.574 ENSMUST00000147671.1
ENSMUST00000145139.1
ENSMUST00000155435.1
 AU019823


expressed sequence AU019823


chr2_+_152962485 0.542 ENSMUST00000099197.2
ENSMUST00000103155.3
 Ttll9

tubulin tyrosine ligase-like family, member 9

chrX_+_52791179 0.533 ENSMUST00000101588.1
 Ccdc160
coiled-coil domain containing 160
chr4_+_74242468 0.516 ENSMUST00000077851.3
 Kdm4c
lysine (K)-specific demethylase 4C
chr19_+_3767953 0.509 ENSMUST00000113970.1
 Suv420h1
suppressor of variegation 4-20 homolog 1 (Drosophila)
chr1_+_118389058 0.498 ENSMUST00000049404.6
ENSMUST00000070989.7
ENSMUST00000165223.1
ENSMUST00000178710.1
 Clasp1



CLIP associating protein 1



chr11_+_70459940 0.406 ENSMUST00000147289.1
ENSMUST00000126105.1
 Zmynd15

zinc finger, MYND-type containing 15

chr9_-_50617428 0.404 ENSMUST00000131351.1
ENSMUST00000171462.1
 AU019823

expressed sequence AU019823

chr14_-_69805524 0.364 ENSMUST00000022665.2
 Rhobtb2
Rho-related BTB domain containing 2
chr1_-_133701881 0.350 ENSMUST00000167348.1
 Gm17678
predicted gene, 17678
chr9_+_109051090 0.337 ENSMUST00000059097.8
 Shisa5
shisa homolog 5 (Xenopus laevis)
chr19_+_44992127 0.336 ENSMUST00000179305.1
 Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr1_-_119836999 0.273 ENSMUST00000163621.1
ENSMUST00000168303.1
 Ptpn4

protein tyrosine phosphatase, non-receptor type 4

chr9_+_87015537 0.269 ENSMUST00000058846.4
 Ripply2
ripply2 homolog (zebrafish)
chr4_+_115000174 0.262 ENSMUST00000129957.1
 Stil
Scl/Tal1 interrupting locus
chr1_+_178187721 0.261 ENSMUST00000159284.1
 Desi2
desumoylating isopeptidase 2
chr18_+_37496997 0.232 ENSMUST00000059571.5
 Pcdhb19
protocadherin beta 19
chr9_-_21312255 0.227 ENSMUST00000115433.3
ENSMUST00000003397.7
 Ap1m2

adaptor protein complex AP-1, mu 2 subunit

chr18_-_43393346 0.216 ENSMUST00000025379.7
 Dpysl3
dihydropyrimidinase-like 3
chr2_-_24049389 0.199 ENSMUST00000051416.5
 Hnmt
histamine N-methyltransferase
chr7_+_48789003 0.183 ENSMUST00000118927.1
ENSMUST00000125280.1
 Zdhhc13

zinc finger, DHHC domain containing 13

chr3_-_63964768 0.172 ENSMUST00000029402.8
 Slc33a1
solute carrier family 33 (acetyl-CoA transporter), member 1
chr1_+_178187417 0.161 ENSMUST00000161075.1
ENSMUST00000027783.7
 Desi2

desumoylating isopeptidase 2

chr1_+_17727034 0.141 ENSMUST00000159958.1
ENSMUST00000160305.1
ENSMUST00000095075.4
 Crispld1


cysteine-rich secretory protein LCCL domain containing 1


chr4_+_115000156 0.132 ENSMUST00000030490.6
 Stil
Scl/Tal1 interrupting locus
chr12_+_81631369 0.124 ENSMUST00000036116.5
 Ttc9
tetratricopeptide repeat domain 9
chr18_-_60848911 0.081 ENSMUST00000177172.1
ENSMUST00000175934.1
ENSMUST00000176630.1
 Tcof1


Treacher Collins Franceschetti syndrome 1, homolog


chr18_-_3281712 0.067 ENSMUST00000182204.1
ENSMUST00000154705.1
ENSMUST00000182833.1
ENSMUST00000151084.1
 Crem



cAMP responsive element modulator



chr7_-_44986313 0.049 ENSMUST00000045325.6
ENSMUST00000085387.4
ENSMUST00000107840.1
ENSMUST00000107843.3
ENSMUST00000107842.3
 Prmt1




protein arginine N-methyltransferase 1




chr3_+_55116174 0.036 ENSMUST00000146109.1
 Spg20
spastic paraplegia 20, spartin (Troyer syndrome) homolog (human)
chr9_+_108460518 0.025 ENSMUST00000061209.5
 Ccdc71
coiled-coil domain containing 71
chrX_+_74424632 0.004 ENSMUST00000114129.2
ENSMUST00000132749.1
 Ikbkg

inhibitor of kappaB kinase gamma


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.2 0.9 GO:0006543 glutamine catabolic process(GO:0006543)
0.2 1.5 GO:0014824 artery smooth muscle contraction(GO:0014824)
0.1 0.5 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.2 GO:0001692 histamine metabolic process(GO:0001692) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.7 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.5 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.4 GO:0033504 floor plate development(GO:0033504)
0.0 1.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.8 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.3 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.0 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.0 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:1990761 growth cone lamellipodium(GO:1990761)
0.1 0.5 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 3.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.8 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.5 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 1.8 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.5 GO:0043198 dendritic shaft(GO:0043198)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0004359 glutaminase activity(GO:0004359)
0.2 3.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.5 GO:0043515 kinetochore binding(GO:0043515)
0.1 1.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.7 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.9 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454) histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.9 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 1.1 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 1.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.0 GO:0030519 snoRNP binding(GO:0030519)
0.0 1.5 GO:0035254 glutamate receptor binding(GO:0035254)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.2 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 2.1 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 0.4 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 1.5 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.9 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.7 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.5 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling