Motif ID: Obox6_Obox5
Z-value: 0.650
![logo of Obox6](../logos/Obox6.png)
![logo of Obox5](../logos/Obox5.png)
Transcription factors associated with Obox6_Obox5:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Obox5 | ENSMUSG00000074366.3 | Obox5 |
Obox6 | ENSMUSG00000041583.7 | Obox6 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 2.8 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
0.4 | 1.3 | GO:0007290 | spermatid nucleus elongation(GO:0007290) |
0.4 | 1.2 | GO:2000312 | regulation of kainate selective glutamate receptor activity(GO:2000312) |
0.3 | 1.4 | GO:0090273 | regulation of somatostatin secretion(GO:0090273) |
0.2 | 0.7 | GO:0010752 | signal complex assembly(GO:0007172) regulation of cGMP-mediated signaling(GO:0010752) |
0.2 | 2.0 | GO:1900034 | regulation of cellular response to heat(GO:1900034) |
0.2 | 0.7 | GO:1904049 | negative regulation of spontaneous neurotransmitter secretion(GO:1904049) |
0.2 | 1.1 | GO:2000065 | negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065) |
0.2 | 0.6 | GO:0042560 | 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560) |
0.2 | 2.9 | GO:0030574 | collagen catabolic process(GO:0030574) |
0.2 | 1.5 | GO:0000055 | ribosomal large subunit export from nucleus(GO:0000055) |
0.2 | 0.8 | GO:0002339 | B cell selection(GO:0002339) |
0.2 | 1.0 | GO:0048254 | snoRNA localization(GO:0048254) |
0.2 | 1.4 | GO:0071420 | cellular response to histamine(GO:0071420) |
0.1 | 6.1 | GO:0010614 | negative regulation of cardiac muscle hypertrophy(GO:0010614) |
0.1 | 1.0 | GO:0019532 | oxalate transport(GO:0019532) |
0.1 | 0.4 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
0.1 | 1.4 | GO:0033152 | immunoglobulin V(D)J recombination(GO:0033152) |
0.1 | 0.4 | GO:2000501 | natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501) |
0.1 | 0.6 | GO:2000298 | regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298) |
0.1 | 0.6 | GO:1903378 | positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
0.1 | 0.5 | GO:0001692 | histamine metabolic process(GO:0001692) imidazole-containing compound catabolic process(GO:0052805) |
0.1 | 0.6 | GO:0046654 | tetrahydrofolate biosynthetic process(GO:0046654) |
0.1 | 0.3 | GO:1903048 | regulation of acetylcholine-gated cation channel activity(GO:1903048) |
0.1 | 0.7 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) phosphate ion transmembrane transport(GO:0035435) cellular trivalent inorganic anion homeostasis(GO:0072502) |
0.1 | 2.8 | GO:0010763 | positive regulation of fibroblast migration(GO:0010763) |
0.1 | 0.5 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
0.1 | 0.3 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
0.1 | 0.6 | GO:1902998 | macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998) |
0.1 | 1.4 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
0.1 | 1.0 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
0.1 | 0.5 | GO:0032237 | activation of store-operated calcium channel activity(GO:0032237) |
0.1 | 0.4 | GO:0040010 | positive regulation of growth rate(GO:0040010) |
0.1 | 0.3 | GO:1900365 | cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248) positive regulation of mRNA polyadenylation(GO:1900365) |
0.1 | 0.6 | GO:0046549 | retinal cone cell development(GO:0046549) |
0.1 | 0.6 | GO:0007258 | JUN phosphorylation(GO:0007258) |
0.1 | 0.1 | GO:1900377 | negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377) |
0.1 | 0.6 | GO:1990416 | cellular response to brain-derived neurotrophic factor stimulus(GO:1990416) |
0.1 | 0.6 | GO:0030718 | germ-line stem cell population maintenance(GO:0030718) |
0.1 | 0.3 | GO:0033087 | negative regulation of immature T cell proliferation(GO:0033087) |
0.1 | 0.5 | GO:0044791 | modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) |
0.1 | 0.3 | GO:0035521 | monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) histone H2A K63-linked deubiquitination(GO:0070537) |
0.1 | 0.3 | GO:1902774 | late endosome to lysosome transport(GO:1902774) |
0.1 | 0.2 | GO:0071873 | response to norepinephrine(GO:0071873) |
0.1 | 7.9 | GO:0006413 | translational initiation(GO:0006413) |
0.1 | 0.5 | GO:0035372 | protein localization to microtubule(GO:0035372) |
0.1 | 0.8 | GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) |
0.1 | 0.2 | GO:2000569 | T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570) |
0.1 | 0.2 | GO:2001160 | regulation of histone H3-K79 methylation(GO:2001160) |
0.1 | 0.7 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
0.1 | 0.5 | GO:0060136 | embryonic process involved in female pregnancy(GO:0060136) |
0.1 | 0.4 | GO:1900113 | negative regulation of histone H3-K9 trimethylation(GO:1900113) |
0.1 | 0.3 | GO:2000346 | negative regulation of hepatocyte proliferation(GO:2000346) |
0.1 | 0.4 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
0.1 | 0.2 | GO:0097360 | chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382) |
0.0 | 0.3 | GO:0045919 | complement activation, alternative pathway(GO:0006957) positive regulation of cytolysis(GO:0045919) |
0.0 | 0.4 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
0.0 | 0.0 | GO:0015747 | urate transport(GO:0015747) |
0.0 | 0.3 | GO:0072656 | NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718) maintenance of protein location in mitochondrion(GO:0072656) |
0.0 | 0.9 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
0.0 | 0.1 | GO:0036228 | protein targeting to nuclear inner membrane(GO:0036228) |
0.0 | 0.1 | GO:2000612 | pronephric field specification(GO:0039003) pattern specification involved in pronephros development(GO:0039017) kidney rudiment formation(GO:0072003) kidney field specification(GO:0072004) positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0072108) regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072304) negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072305) mesenchymal cell apoptotic process involved in metanephros development(GO:1900200) apoptotic process involved in metanephric collecting duct development(GO:1900204) apoptotic process involved in metanephric nephron tubule development(GO:1900205) regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900211) negative regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900212) regulation of apoptotic process involved in metanephric collecting duct development(GO:1900214) negative regulation of apoptotic process involved in metanephric collecting duct development(GO:1900215) regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900217) negative regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900218) mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:1901147) regulation of metanephric DCT cell differentiation(GO:2000592) positive regulation of metanephric DCT cell differentiation(GO:2000594) regulation of thyroid-stimulating hormone secretion(GO:2000612) |
0.0 | 0.1 | GO:1903225 | regulation of endodermal cell fate specification(GO:0042663) negative regulation of endodermal cell differentiation(GO:1903225) |
0.0 | 0.1 | GO:0044837 | assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) |
0.0 | 0.3 | GO:1901525 | negative regulation of macromitophagy(GO:1901525) negative regulation of mitophagy(GO:1903147) |
0.0 | 0.6 | GO:0010818 | T cell chemotaxis(GO:0010818) |
0.0 | 0.1 | GO:0042938 | dipeptide transport(GO:0042938) |
0.0 | 0.2 | GO:0010792 | DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) |
0.0 | 0.3 | GO:0016114 | terpenoid biosynthetic process(GO:0016114) |
0.0 | 0.2 | GO:0008272 | sulfate transport(GO:0008272) |
0.0 | 0.9 | GO:0007097 | nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023) |
0.0 | 0.2 | GO:1990564 | protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
0.0 | 0.4 | GO:1901898 | regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.0 | 0.1 | GO:0008594 | photoreceptor cell morphogenesis(GO:0008594) |
0.0 | 0.3 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
0.0 | 0.2 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207) |
0.0 | 0.9 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
0.0 | 0.3 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
0.0 | 0.2 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
0.0 | 0.2 | GO:0046826 | negative regulation of protein export from nucleus(GO:0046826) |
0.0 | 0.4 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
0.0 | 0.1 | GO:0046689 | response to mercury ion(GO:0046689) |
0.0 | 0.5 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
0.0 | 0.1 | GO:0046415 | urate metabolic process(GO:0046415) |
0.0 | 0.2 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
0.0 | 0.3 | GO:0035721 | intraciliary retrograde transport(GO:0035721) |
0.0 | 0.7 | GO:0030325 | adrenal gland development(GO:0030325) |
0.0 | 0.1 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
0.0 | 0.1 | GO:2001271 | negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271) |
0.0 | 0.4 | GO:0016558 | protein import into peroxisome matrix(GO:0016558) |
0.0 | 1.5 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
0.0 | 0.0 | GO:0051599 | response to hydrostatic pressure(GO:0051599) |
0.0 | 0.4 | GO:0051491 | positive regulation of filopodium assembly(GO:0051491) |
0.0 | 0.2 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
0.0 | 0.0 | GO:0070560 | protein secretion by platelet(GO:0070560) |
0.0 | 3.2 | GO:0031032 | actomyosin structure organization(GO:0031032) |
0.0 | 0.3 | GO:0002031 | G-protein coupled receptor internalization(GO:0002031) |
0.0 | 0.3 | GO:0032933 | response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) negative regulation of fatty acid biosynthetic process(GO:0045717) cellular response to sterol depletion(GO:0071501) |
0.0 | 0.1 | GO:1990009 | retinal cell apoptotic process(GO:1990009) |
0.0 | 0.5 | GO:0007193 | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193) |
0.0 | 0.2 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
0.0 | 0.5 | GO:0021591 | ventricular system development(GO:0021591) |
0.0 | 0.1 | GO:0035457 | cellular response to interferon-alpha(GO:0035457) |
0.0 | 0.4 | GO:0007608 | sensory perception of smell(GO:0007608) |
0.0 | 0.0 | GO:0045922 | negative regulation of fatty acid metabolic process(GO:0045922) |
0.0 | 0.2 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
0.0 | 1.5 | GO:0007286 | spermatid development(GO:0007286) |
0.0 | 0.2 | GO:0070995 | NADPH oxidation(GO:0070995) |
0.0 | 0.2 | GO:0006353 | DNA-templated transcription, termination(GO:0006353) |
0.0 | 0.2 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
0.0 | 0.1 | GO:0006983 | ER overload response(GO:0006983) |
0.0 | 0.3 | GO:0099612 | protein localization to axon(GO:0099612) |
0.0 | 0.5 | GO:0001825 | blastocyst formation(GO:0001825) |
0.0 | 0.1 | GO:0036112 | medium-chain fatty-acyl-CoA metabolic process(GO:0036112) |
0.0 | 0.2 | GO:0006198 | cAMP catabolic process(GO:0006198) |
0.0 | 0.2 | GO:0016578 | histone deubiquitination(GO:0016578) |
0.0 | 0.2 | GO:0051451 | myoblast migration(GO:0051451) |
0.0 | 0.6 | GO:0000380 | alternative mRNA splicing, via spliceosome(GO:0000380) |
0.0 | 0.0 | GO:1901642 | purine nucleoside transmembrane transport(GO:0015860) nucleoside transmembrane transport(GO:1901642) |
0.0 | 0.7 | GO:0035249 | synaptic transmission, glutamatergic(GO:0035249) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 1.4 | GO:0005958 | DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) |
0.2 | 2.6 | GO:0097418 | neurofibrillary tangle(GO:0097418) |
0.2 | 0.8 | GO:0019815 | B cell receptor complex(GO:0019815) |
0.2 | 1.6 | GO:0002177 | manchette(GO:0002177) |
0.2 | 0.6 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
0.2 | 1.3 | GO:0060091 | kinocilium(GO:0060091) |
0.2 | 0.6 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
0.1 | 0.7 | GO:1990761 | growth cone lamellipodium(GO:1990761) |
0.1 | 0.5 | GO:0032585 | multivesicular body membrane(GO:0032585) |
0.1 | 0.4 | GO:1990415 | Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429) |
0.1 | 1.4 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
0.1 | 1.0 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
0.1 | 1.0 | GO:0070761 | pre-snoRNP complex(GO:0070761) |
0.1 | 0.4 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
0.1 | 1.0 | GO:0016442 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
0.1 | 0.7 | GO:0005642 | annulate lamellae(GO:0005642) |
0.1 | 0.3 | GO:1990769 | proximal neuron projection(GO:1990769) |
0.1 | 6.7 | GO:0016605 | PML body(GO:0016605) |
0.0 | 2.4 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.0 | 0.3 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
0.0 | 0.3 | GO:0033263 | CORVET complex(GO:0033263) |
0.0 | 1.8 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
0.0 | 0.7 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
0.0 | 0.3 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
0.0 | 0.7 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
0.0 | 0.2 | GO:1990745 | EARP complex(GO:1990745) |
0.0 | 0.3 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
0.0 | 0.4 | GO:0034464 | BBSome(GO:0034464) |
0.0 | 0.2 | GO:0070531 | BRCA1-A complex(GO:0070531) |
0.0 | 0.1 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
0.0 | 0.1 | GO:0044613 | nuclear pore central transport channel(GO:0044613) |
0.0 | 0.4 | GO:0071004 | U2 snRNP(GO:0005686) U2-type prespliceosome(GO:0071004) |
0.0 | 0.6 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
0.0 | 0.1 | GO:0005903 | brush border(GO:0005903) |
0.0 | 0.1 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
0.0 | 0.2 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
0.0 | 0.2 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
0.0 | 0.9 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
0.0 | 0.2 | GO:0016342 | catenin complex(GO:0016342) |
0.0 | 1.0 | GO:0045211 | postsynaptic membrane(GO:0045211) |
0.0 | 0.2 | GO:0000124 | SAGA complex(GO:0000124) |
0.0 | 0.6 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
0.0 | 0.1 | GO:0001520 | outer dense fiber(GO:0001520) |
0.0 | 0.1 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
0.0 | 0.3 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
0.0 | 0.2 | GO:0097539 | ciliary transition fiber(GO:0097539) |
0.0 | 0.2 | GO:0036038 | MKS complex(GO:0036038) |
0.0 | 0.1 | GO:0071986 | Ragulator complex(GO:0071986) |
0.0 | 0.1 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
0.0 | 0.7 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.0 | 0.2 | GO:0098984 | asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984) |
0.0 | 0.2 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 2.8 | GO:0017095 | heparan sulfate 6-O-sulfotransferase activity(GO:0017095) |
0.3 | 1.0 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
0.3 | 2.0 | GO:0099609 | microtubule lateral binding(GO:0099609) |
0.2 | 1.4 | GO:0022851 | GABA-gated chloride ion channel activity(GO:0022851) |
0.2 | 0.7 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
0.2 | 1.3 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
0.2 | 0.6 | GO:0008502 | melatonin receptor activity(GO:0008502) |
0.2 | 0.6 | GO:0016155 | formyltetrahydrofolate dehydrogenase activity(GO:0016155) |
0.2 | 1.0 | GO:1990599 | 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599) |
0.1 | 0.6 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
0.1 | 0.8 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
0.1 | 2.8 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
0.1 | 8.5 | GO:0003743 | translation initiation factor activity(GO:0003743) |
0.1 | 0.6 | GO:0050816 | phosphothreonine binding(GO:0050816) |
0.1 | 0.4 | GO:0004677 | DNA-dependent protein kinase activity(GO:0004677) |
0.1 | 0.6 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
0.1 | 0.4 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
0.1 | 0.4 | GO:0004111 | creatine kinase activity(GO:0004111) |
0.1 | 2.9 | GO:0001968 | fibronectin binding(GO:0001968) |
0.1 | 1.9 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
0.1 | 1.4 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
0.1 | 1.0 | GO:0019531 | secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531) |
0.1 | 0.7 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
0.1 | 0.3 | GO:0019808 | polyamine binding(GO:0019808) |
0.1 | 1.4 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
0.1 | 0.3 | GO:0004703 | G-protein coupled receptor kinase activity(GO:0004703) |
0.1 | 0.7 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
0.1 | 0.5 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
0.1 | 0.7 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
0.1 | 0.3 | GO:0001851 | complement component C3b binding(GO:0001851) |
0.1 | 0.3 | GO:0008865 | fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
0.1 | 2.4 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
0.1 | 0.2 | GO:0071568 | UFM1 transferase activity(GO:0071568) |
0.1 | 0.4 | GO:0004984 | olfactory receptor activity(GO:0004984) |
0.1 | 0.6 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
0.1 | 1.3 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
0.1 | 1.0 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
0.0 | 0.8 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
0.0 | 0.1 | GO:0035673 | oligopeptide transmembrane transporter activity(GO:0035673) dipeptide transporter activity(GO:0042936) |
0.0 | 0.3 | GO:0004311 | farnesyltranstransferase activity(GO:0004311) |
0.0 | 0.9 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
0.0 | 0.2 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
0.0 | 0.2 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
0.0 | 5.8 | GO:0001191 | transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191) |
0.0 | 0.4 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
0.0 | 3.4 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.0 | 0.1 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
0.0 | 0.9 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.0 | 0.2 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
0.0 | 0.3 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
0.0 | 0.1 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
0.0 | 0.3 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
0.0 | 1.0 | GO:0008009 | chemokine activity(GO:0008009) |
0.0 | 0.2 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
0.0 | 0.1 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
0.0 | 0.2 | GO:0004118 | cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) |
0.0 | 0.5 | GO:0031489 | myosin V binding(GO:0031489) |
0.0 | 1.7 | GO:0019894 | kinesin binding(GO:0019894) |
0.0 | 0.1 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
0.0 | 1.2 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
0.0 | 0.1 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
0.0 | 0.3 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
0.0 | 1.2 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
0.0 | 0.9 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
0.0 | 0.3 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
0.0 | 0.2 | GO:0045294 | alpha-catenin binding(GO:0045294) |
0.0 | 0.2 | GO:0008235 | metalloexopeptidase activity(GO:0008235) |
0.0 | 0.1 | GO:0003996 | acyl-CoA ligase activity(GO:0003996) |
0.0 | 0.1 | GO:0008392 | arachidonic acid epoxygenase activity(GO:0008392) |
0.0 | 0.3 | GO:0008097 | 5S rRNA binding(GO:0008097) |
0.0 | 0.1 | GO:0004768 | stearoyl-CoA 9-desaturase activity(GO:0004768) |
0.0 | 0.1 | GO:0043515 | kinetochore binding(GO:0043515) |
0.0 | 0.3 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
0.0 | 0.1 | GO:1990405 | protein antigen binding(GO:1990405) |
0.0 | 0.2 | GO:0031005 | filamin binding(GO:0031005) |
0.0 | 0.7 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.0 | 0.0 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
0.0 | 0.0 | GO:0015038 | glutathione disulfide oxidoreductase activity(GO:0015038) |
0.0 | 0.4 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.0 | 0.3 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
0.0 | 0.2 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 2.4 | PID_THROMBIN_PAR4_PATHWAY | PAR4-mediated thrombin signaling events |
0.1 | 1.9 | PID_P38_GAMMA_DELTA_PATHWAY | Signaling mediated by p38-gamma and p38-delta |
0.1 | 2.2 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
0.0 | 0.5 | PID_S1P_S1P4_PATHWAY | S1P4 pathway |
0.0 | 0.8 | PID_AR_NONGENOMIC_PATHWAY | Nongenotropic Androgen signaling |
0.0 | 0.7 | SA_PTEN_PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
0.0 | 1.9 | PID_HEDGEHOG_GLI_PATHWAY | Hedgehog signaling events mediated by Gli proteins |
0.0 | 1.1 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
0.0 | 0.2 | PID_BARD1_PATHWAY | BARD1 signaling events |
0.0 | 0.7 | PID_MYC_PATHWAY | C-MYC pathway |
0.0 | 0.8 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
0.0 | 0.9 | PID_ERBB1_INTERNALIZATION_PATHWAY | Internalization of ErbB1 |
0.0 | 1.3 | PID_CDC42_PATHWAY | CDC42 signaling events |
0.0 | 0.6 | ST_ADRENERGIC | Adrenergic Pathway |
0.0 | 3.0 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.0 | 0.8 | PID_KIT_PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
0.0 | 0.7 | PID_TRKR_PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
0.0 | 0.2 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
0.0 | 0.4 | PID_DNA_PK_PATHWAY | DNA-PK pathway in nonhomologous end joining |
0.0 | 0.6 | PID_MYC_REPRESS_PATHWAY | Validated targets of C-MYC transcriptional repression |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 2.9 | REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
0.1 | 0.3 | REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS | Genes involved in Hormone ligand-binding receptors |
0.1 | 2.0 | REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
0.1 | 1.4 | REACTOME_GABA_A_RECEPTOR_ACTIVATION | Genes involved in GABA A receptor activation |
0.1 | 2.9 | REACTOME_G_PROTEIN_ACTIVATION | Genes involved in G-protein activation |
0.1 | 2.7 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
0.1 | 0.6 | REACTOME_GAP_JUNCTION_DEGRADATION | Genes involved in Gap junction degradation |
0.1 | 0.3 | REACTOME_REGULATION_OF_COMPLEMENT_CASCADE | Genes involved in Regulation of Complement cascade |
0.1 | 1.0 | REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP | Genes involved in Destabilization of mRNA by Tristetraprolin (TTP) |
0.1 | 1.0 | REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
0.0 | 0.3 | REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
0.0 | 0.7 | REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
0.0 | 0.6 | REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
0.0 | 1.0 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
0.0 | 0.7 | REACTOME_SIGNAL_ATTENUATION | Genes involved in Signal attenuation |
0.0 | 1.8 | REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
0.0 | 0.3 | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
0.0 | 0.7 | REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
0.0 | 0.4 | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | Genes involved in CRMPs in Sema3A signaling |
0.0 | 0.7 | REACTOME_MRNA_3_END_PROCESSING | Genes involved in mRNA 3'-end processing |
0.0 | 0.5 | REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
0.0 | 0.4 | REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
0.0 | 0.4 | REACTOME_DEADENYLATION_OF_MRNA | Genes involved in Deadenylation of mRNA |
0.0 | 0.4 | REACTOME_DOUBLE_STRAND_BREAK_REPAIR | Genes involved in Double-Strand Break Repair |
0.0 | 0.3 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
0.0 | 0.1 | REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
0.0 | 0.4 | REACTOME_MRNA_SPLICING_MINOR_PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |